#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q8WSF8 uniprotkb:Q8WSF8 intact:EBI-7179765|intact:MINT-7300724 intact:EBI-7179765|intact:MINT-7300724 psi-mi:q8wsf8_aplca(display_long) psi-mi:q8wsf8_aplca(display_long) psi-mi:"MI:0114"(x-ray crystallography) Celie et al. (2005) pubmed:15951818|doi:10.1038/nsmb951|imex:IM-21594 taxid:6500(aplca)|taxid:6500("Aplysia californica (California sea hare)") taxid:6500(aplca)|taxid:6500("Aplysia californica (California sea hare)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15553582|imex:IM-21594-1|dip:DIP-87878E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q8WSF8|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005230"(extracellular ligand-gated ion channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR036734|rcsb pdb:2BR7|rcsb pdb:2BR8|rcsb pdb:2BYN|rcsb pdb:2BYP|rcsb pdb:2BYQ|rcsb pdb:2BYR|rcsb pdb:2BYS|rcsb pdb:2C9T|rcsb pdb:2PGZ|rcsb pdb:2PH9|rcsb pdb:2UZ6|rcsb pdb:2W8F|rcsb pdb:2W8G|rcsb pdb:2WN9|rcsb pdb:2WNC|rcsb pdb:2WNJ|rcsb pdb:2WNL|rcsb pdb:2WZY|rcsb pdb:2X00|rcsb pdb:2XNT|rcsb pdb:2XNU|rcsb pdb:2XNV|rcsb pdb:2XYS|rcsb pdb:2XYT|rcsb pdb:2XZ5|rcsb pdb:2XZ6|rcsb pdb:2Y54|rcsb pdb:2Y56|rcsb pdb:2Y57|rcsb pdb:2Y58|rcsb pdb:2Y7Y|rcsb pdb:2YMD|rcsb pdb:2YME|rcsb pdb:3C79|rcsb pdb:3C84|rcsb pdb:3GUA|rcsb pdb:3PEO|rcsb pdb:3PMZ|rcsb pdb:3SH1|rcsb pdb:3SIO|rcsb pdb:3T4M|rcsb pdb:4AFT|rcsb pdb:4BFQ|rcsb pdb:4BQT|rcsb pdb:4DBM|rcsb pdb:4EZ1|rcsb pdb:4FRR|rcsb pdb:4WV9|rcsb pdb:4XHE|rcsb pdb:4XK9|rcsb pdb:4ZJS|rcsb pdb:4ZK4|rcsb pdb:5AIN|rcsb pdb:5BRX|rcsb pdb:5BW2|rcsb pdb:5CO5|rcsb pdb:5JME|rcsb pdb:5KE4|rcsb pdb:5KZU|rcsb pdb:5LXB|rcsb pdb:5O87|rcsb pdb:5O8T|rcsb pdb:5OA0|rcsb pdb:5OAD|rcsb pdb:5OAJ|rcsb pdb:5OAL|rcsb pdb:5OAN|rcsb pdb:5OBG|rcsb pdb:5OBH|rcsb pdb:5SYO|rcsb pdb:5TSF|rcsb pdb:5TVC|rcsb pdb:5TVH|rcsb pdb:5XGL|rcsb pdb:6M4X|rcsb pdb:6M4Z|rcsb pdb:6QKK|rcsb pdb:6QQO|rcsb pdb:6QQP|rcsb pdb:6SGV|rcsb pdb:6SH0|rcsb pdb:6T9R|refseq:NP_001191488.1|dip:DIP-46103N mint:Q8WSF8|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005230"(extracellular ligand-gated ion channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR036734|rcsb pdb:2BR7|rcsb pdb:2BR8|rcsb pdb:2BYN|rcsb pdb:2BYP|rcsb pdb:2BYQ|rcsb pdb:2BYR|rcsb pdb:2BYS|rcsb pdb:2C9T|rcsb pdb:2PGZ|rcsb pdb:2PH9|rcsb pdb:2UZ6|rcsb pdb:2W8F|rcsb pdb:2W8G|rcsb pdb:2WN9|rcsb pdb:2WNC|rcsb pdb:2WNJ|rcsb pdb:2WNL|rcsb pdb:2WZY|rcsb pdb:2X00|rcsb pdb:2XNT|rcsb pdb:2XNU|rcsb pdb:2XNV|rcsb pdb:2XYS|rcsb pdb:2XYT|rcsb pdb:2XZ5|rcsb pdb:2XZ6|rcsb pdb:2Y54|rcsb pdb:2Y56|rcsb pdb:2Y57|rcsb pdb:2Y58|rcsb pdb:2Y7Y|rcsb pdb:2YMD|rcsb pdb:2YME|rcsb pdb:3C79|rcsb pdb:3C84|rcsb pdb:3GUA|rcsb pdb:3PEO|rcsb pdb:3PMZ|rcsb pdb:3SH1|rcsb pdb:3SIO|rcsb pdb:3T4M|rcsb pdb:4AFT|rcsb pdb:4BFQ|rcsb pdb:4BQT|rcsb pdb:4DBM|rcsb pdb:4EZ1|rcsb pdb:4FRR|rcsb pdb:4WV9|rcsb pdb:4XHE|rcsb pdb:4XK9|rcsb pdb:4ZJS|rcsb pdb:4ZK4|rcsb pdb:5AIN|rcsb pdb:5BRX|rcsb pdb:5BW2|rcsb pdb:5CO5|rcsb pdb:5JME|rcsb pdb:5KE4|rcsb pdb:5KZU|rcsb pdb:5LXB|rcsb pdb:5O87|rcsb pdb:5O8T|rcsb pdb:5OA0|rcsb pdb:5OAD|rcsb pdb:5OAJ|rcsb pdb:5OAL|rcsb pdb:5OAN|rcsb pdb:5OBG|rcsb pdb:5OBH|rcsb pdb:5SYO|rcsb pdb:5TSF|rcsb pdb:5TVC|rcsb pdb:5TVH|rcsb pdb:5XGL|rcsb pdb:6M4X|rcsb pdb:6M4Z|rcsb pdb:6QKK|rcsb pdb:6QQO|rcsb pdb:6QQP|rcsb pdb:6SGV|rcsb pdb:6SH0|rcsb pdb:6T9R|refseq:NP_001191488.1|dip:DIP-46103N psi-mi:"MI:0465"(dip) comment:mint comment:mint full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr)|taxid:7108("Spodoptera frugiperda (Fall armyworm)") - 2017/08/04 2017/08/10 rogid:piXc6U3EgPUlWwmm/Npyntm1XbQ6500 rogid:piXc6U3EgPUlWwmm/Npyntm1XbQ6500 rigid:diREEoQ79yzPQ8BWHgNrXiYdowQ false - - - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P58154 uniprotkb:P50984 intact:EBI-7516292|intact:MINT-5223682 intact:EBI-15553601 psi-mi:achp_lymst(display_long) psi-mi:ca1a_conpe(display_long) psi-mi:"MI:0065"(isothermal titration calorimetry) Celie et al. (2005) pubmed:15951818|doi:10.1038/nsmb951|imex:IM-21594 taxid:6523(lymst)|taxid:6523(Lymnaea stagnalis) taxid:37335(conpe)|taxid:37335(Conus pennaceus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15553611|imex:IM-21594-2|dip:DIP-192006E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P58154|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005230"(extracellular ligand-gated ion channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043083"(synaptic cleft)|go:"GO:0045202"(synapse)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR036734|rcsb pdb:1I9B|rcsb pdb:1UV6|rcsb pdb:1UW6|rcsb pdb:1UX2|rcsb pdb:1YI5|rcsb pdb:2ZJU|rcsb pdb:2ZJV|rcsb pdb:3U8J|rcsb pdb:3U8K|rcsb pdb:3U8L|rcsb pdb:3U8M|rcsb pdb:3U8N|rcsb pdb:3WIP|rcsb pdb:3WTH|rcsb pdb:3WTI|rcsb pdb:3WTJ|rcsb pdb:3WTK|rcsb pdb:3WTL|rcsb pdb:3WTM|rcsb pdb:3WTN|rcsb pdb:3WTO|rcsb pdb:3ZDG|rcsb pdb:3ZDH|rcsb pdb:4ALX|rcsb pdb:4HQP|rcsb pdb:4NZB|rcsb pdb:4QAA|rcsb pdb:4QAB|rcsb pdb:4QAC|rcsb pdb:4UM1|rcsb pdb:4UM3|rcsb pdb:4ZJT|rcsb pdb:4ZK1|rcsb pdb:4ZR6|rcsb pdb:4ZRU|rcsb pdb:5AFH|rcsb pdb:5AFJ|rcsb pdb:5AFK|rcsb pdb:5AFL|rcsb pdb:5AFN|rcsb pdb:5BP0|rcsb pdb:5J5F|rcsb pdb:5J5G|rcsb pdb:5J5H|rcsb pdb:5J5I|rcsb pdb:5T90|rcsb pdb:5Y2Q|rcsb pdb:7NDP|rcsb pdb:7NDV|rcsb pdb:5AFM|dip:DIP-43985N go:"GO:0005576"(extracellular region)|go:"GO:0035792"(host cell postsynaptic membrane)|go:"GO:0090729"(toxin activity)|interpro:IPR018072|rcsb pdb:1PEN|rcsb pdb:2BR8|dip:DIP-60493N psi-mi:"MI:0465"(dip) comment:mint|function:Binds to acetylcholine. Modulates neuronal synaptic transmission - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/04 2017/08/10 rogid:tKf2LBq8RrKU2a89gKKrF4oWBzo6523 rogid:CeXUI+yShm9v6+fAaKmgkrDty9437335 rigid:J0awaBft6J+7/zPJrshI3eN+DcY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8WSF8 uniprotkb:P50984 intact:EBI-7179765|intact:MINT-7300724 intact:EBI-15553601 psi-mi:q8wsf8_aplca(display_long) psi-mi:ca1a_conpe(display_long) psi-mi:"MI:0114"(x-ray crystallography) Celie et al. (2005) pubmed:15951818|doi:10.1038/nsmb951|imex:IM-21594 taxid:6500(aplca)|taxid:6500("Aplysia californica (California sea hare)") taxid:37335(conpe)|taxid:37335(Conus pennaceus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15553629|imex:IM-21594-3|dip:DIP-192005E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q8WSF8|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005230"(extracellular ligand-gated ion channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR036734|rcsb pdb:2BR7|rcsb pdb:2BR8|rcsb pdb:2BYN|rcsb pdb:2BYP|rcsb pdb:2BYQ|rcsb pdb:2BYR|rcsb pdb:2BYS|rcsb pdb:2C9T|rcsb pdb:2PGZ|rcsb pdb:2PH9|rcsb pdb:2UZ6|rcsb pdb:2W8F|rcsb pdb:2W8G|rcsb pdb:2WN9|rcsb pdb:2WNC|rcsb pdb:2WNJ|rcsb pdb:2WNL|rcsb pdb:2WZY|rcsb pdb:2X00|rcsb pdb:2XNT|rcsb pdb:2XNU|rcsb pdb:2XNV|rcsb pdb:2XYS|rcsb pdb:2XYT|rcsb pdb:2XZ5|rcsb pdb:2XZ6|rcsb pdb:2Y54|rcsb pdb:2Y56|rcsb pdb:2Y57|rcsb pdb:2Y58|rcsb pdb:2Y7Y|rcsb pdb:2YMD|rcsb pdb:2YME|rcsb pdb:3C79|rcsb pdb:3C84|rcsb pdb:3GUA|rcsb pdb:3PEO|rcsb pdb:3PMZ|rcsb pdb:3SH1|rcsb pdb:3SIO|rcsb pdb:3T4M|rcsb pdb:4AFT|rcsb pdb:4BFQ|rcsb pdb:4BQT|rcsb pdb:4DBM|rcsb pdb:4EZ1|rcsb pdb:4FRR|rcsb pdb:4WV9|rcsb pdb:4XHE|rcsb pdb:4XK9|rcsb pdb:4ZJS|rcsb pdb:4ZK4|rcsb pdb:5AIN|rcsb pdb:5BRX|rcsb pdb:5BW2|rcsb pdb:5CO5|rcsb pdb:5JME|rcsb pdb:5KE4|rcsb pdb:5KZU|rcsb pdb:5LXB|rcsb pdb:5O87|rcsb pdb:5O8T|rcsb pdb:5OA0|rcsb pdb:5OAD|rcsb pdb:5OAJ|rcsb pdb:5OAL|rcsb pdb:5OAN|rcsb pdb:5OBG|rcsb pdb:5OBH|rcsb pdb:5SYO|rcsb pdb:5TSF|rcsb pdb:5TVC|rcsb pdb:5TVH|rcsb pdb:5XGL|rcsb pdb:6M4X|rcsb pdb:6M4Z|rcsb pdb:6QKK|rcsb pdb:6QQO|rcsb pdb:6QQP|rcsb pdb:6SGV|rcsb pdb:6SH0|rcsb pdb:6T9R|refseq:NP_001191488.1|dip:DIP-46103N go:"GO:0005576"(extracellular region)|go:"GO:0035792"(host cell postsynaptic membrane)|go:"GO:0090729"(toxin activity)|interpro:IPR018072|rcsb pdb:1PEN|rcsb pdb:2BR8|dip:DIP-60493N psi-mi:"MI:0465"(dip) comment:mint - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/04 2017/08/10 rogid:piXc6U3EgPUlWwmm/Npyntm1XbQ6500 rogid:CeXUI+yShm9v6+fAaKmgkrDty9437335 rigid:yQZcW2mtj1h7gusmij9q4AdV2gw false - mutation:14-14,10-10 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8WSF8 uniprotkb:P50984 intact:EBI-7179765|intact:MINT-7300724 intact:EBI-15553601 psi-mi:q8wsf8_aplca(display_long) psi-mi:ca1a_conpe(display_long) psi-mi:"MI:0065"(isothermal titration calorimetry) Celie et al. (2005) pubmed:15951818|doi:10.1038/nsmb951|imex:IM-21594 taxid:6500(aplca)|taxid:6500("Aplysia californica (California sea hare)") taxid:37335(conpe)|taxid:37335(Conus pennaceus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15553650|imex:IM-21594-4|dip:DIP-192005E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q8WSF8|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005230"(extracellular ligand-gated ion channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR036734|rcsb pdb:2BR7|rcsb pdb:2BR8|rcsb pdb:2BYN|rcsb pdb:2BYP|rcsb pdb:2BYQ|rcsb pdb:2BYR|rcsb pdb:2BYS|rcsb pdb:2C9T|rcsb pdb:2PGZ|rcsb pdb:2PH9|rcsb pdb:2UZ6|rcsb pdb:2W8F|rcsb pdb:2W8G|rcsb pdb:2WN9|rcsb pdb:2WNC|rcsb pdb:2WNJ|rcsb pdb:2WNL|rcsb pdb:2WZY|rcsb pdb:2X00|rcsb pdb:2XNT|rcsb pdb:2XNU|rcsb pdb:2XNV|rcsb pdb:2XYS|rcsb pdb:2XYT|rcsb pdb:2XZ5|rcsb pdb:2XZ6|rcsb pdb:2Y54|rcsb pdb:2Y56|rcsb pdb:2Y57|rcsb pdb:2Y58|rcsb pdb:2Y7Y|rcsb pdb:2YMD|rcsb pdb:2YME|rcsb pdb:3C79|rcsb pdb:3C84|rcsb pdb:3GUA|rcsb pdb:3PEO|rcsb pdb:3PMZ|rcsb pdb:3SH1|rcsb pdb:3SIO|rcsb pdb:3T4M|rcsb pdb:4AFT|rcsb pdb:4BFQ|rcsb pdb:4BQT|rcsb pdb:4DBM|rcsb pdb:4EZ1|rcsb pdb:4FRR|rcsb pdb:4WV9|rcsb pdb:4XHE|rcsb pdb:4XK9|rcsb pdb:4ZJS|rcsb pdb:4ZK4|rcsb pdb:5AIN|rcsb pdb:5BRX|rcsb pdb:5BW2|rcsb pdb:5CO5|rcsb pdb:5JME|rcsb pdb:5KE4|rcsb pdb:5KZU|rcsb pdb:5LXB|rcsb pdb:5O87|rcsb pdb:5O8T|rcsb pdb:5OA0|rcsb pdb:5OAD|rcsb pdb:5OAJ|rcsb pdb:5OAL|rcsb pdb:5OAN|rcsb pdb:5OBG|rcsb pdb:5OBH|rcsb pdb:5SYO|rcsb pdb:5TSF|rcsb pdb:5TVC|rcsb pdb:5TVH|rcsb pdb:5XGL|rcsb pdb:6M4X|rcsb pdb:6M4Z|rcsb pdb:6QKK|rcsb pdb:6QQO|rcsb pdb:6QQP|rcsb pdb:6SGV|rcsb pdb:6SH0|rcsb pdb:6T9R|refseq:NP_001191488.1|dip:DIP-46103N go:"GO:0005576"(extracellular region)|go:"GO:0035792"(host cell postsynaptic membrane)|go:"GO:0090729"(toxin activity)|interpro:IPR018072|rcsb pdb:1PEN|rcsb pdb:2BR8|dip:DIP-60493N psi-mi:"MI:0465"(dip) comment:mint - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/04 2017/08/10 rogid:piXc6U3EgPUlWwmm/Npyntm1XbQ6500 rogid:CeXUI+yShm9v6+fAaKmgkrDty9437335 rigid:yQZcW2mtj1h7gusmij9q4AdV2gw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)