#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9H840 uniprotkb:Q8WXD5 intact:EBI-715455|uniprotkb:Q6IA34|ensembl:ENSP00000375813|ensembl:ENSP00000465704|ensembl:ENSP00000466342|ensembl:ENSP00000270257 intact:EBI-752301|uniprotkb:Q53SI5|uniprotkb:Q8WVB4|uniprotkb:Q9H5G6|uniprotkb:B2RDP8|ensembl:ENSP00000281950 psi-mi:gemi7_human(display_long)|uniprotkb:SIP3(gene name synonym)|uniprotkb:GEMIN7(gene name)|psi-mi:GEMIN7(display_short) psi-mi:gemi6_human(display_long)|uniprotkb:SIP2(gene name synonym)|uniprotkb:GEMIN6(gene name)|psi-mi:GEMIN6(display_short) psi-mi:"MI:0114"(x-ray crystallography) Ma et al. (2005) pubmed:15939020|doi:10.1016/j.str.2005.03.014|imex:IM-14201 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15552897|imex:IM-14201-1|dip:DIP-71041E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_005259319.1|refseq:XP_005259320.1|refseq:NP_001007270.1|refseq:NP_001007271.1|refseq:NP_078983.1|ensembl:ENSG00000142252(gene)|ensembl:ENST00000270257(transcript)|ensembl:ENST00000391951(transcript)|ensembl:ENST00000591607(transcript)|ensembl:ENST00000591747(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|go:"GO:0032797"(SMN complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0097504"(Gemini of coiled bodies)|go:"GO:0120114"(Sm-like protein family complex)|interpro:IPR020338|interpro:IPR024642|mint:Q9H840|rcsb pdb:1Y96|rcsb pdb:7BBL|reactome:R-HSA-191859|refseq:NP_001305983.1|refseq:NP_001305984.1|refseq:XP_016882801.1|dip:DIP-41750N refseq:NP_079051.9|dip:DIP-41331N|ensembl:ENSG00000152147(gene)|ensembl:ENST00000281950(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|go:"GO:0032797"(SMN complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0097504"(Gemini of coiled bodies)|interpro:IPR009422(Gemin6)|mint:Q8WXD5|rcsb pdb:1Y96|rcsb pdb:7BBL|reactome:R-HSA-191859 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/04 2017/08/10 rogid:jnNKbzuQxiIWKDmv7+je9B5U81Q9606 rogid:AaQyOsKgOMpkny7dYKmgwu0/c1g9606 rigid:LYSL0nwZ0RHQjHdRej0FHExESss false binding-associated region:31-131 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P62308 uniprotkb:Q8WXD5 intact:EBI-624585|uniprotkb:Q15357|uniprotkb:Q6IB86|ensembl:ENSP00000272348|intact:EBI-1056206|uniprotkb:D6W5G6 intact:EBI-752301|uniprotkb:Q53SI5|uniprotkb:Q8WVB4|uniprotkb:Q9H5G6|uniprotkb:B2RDP8|ensembl:ENSP00000281950 psi-mi:ruxg_human(display_long)|uniprotkb:SNRPG(gene name)|psi-mi:SNRPG(display_short)|uniprotkb:PBSCG(gene name synonym)|uniprotkb:Sm protein G(gene name synonym) psi-mi:gemi6_human(display_long)|uniprotkb:SIP2(gene name synonym)|uniprotkb:GEMIN6(gene name)|psi-mi:GEMIN6(display_short) psi-mi:"MI:0096"(pull down) Ma et al. (2005) pubmed:15939020|doi:10.1016/j.str.2005.03.014|imex:IM-14201 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15552939|imex:IM-14201-3|dip:DIP-102913E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0097526"(spliceosomal tri-snRNP complex)|ensembl:ENSG00000143977(gene)|ensembl:ENST00000272348(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005683"(U7 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0008380"(RNA splicing)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0034709"(methylosome)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0043186"(P granule)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|rcsb pdb:6QDV|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:6V4X|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7A5P|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7B0Y|rcsb pdb:7DVQ|reactome:R-HSA-111367|reactome:R-HSA-191859|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-73856|reactome:R-HSA-77588|go:"GO:1990446"(U1 snRNP binding)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR034098|interpro:IPR044641|mint:P62308|rcsb pdb:3CW1|rcsb pdb:3JCR|rcsb pdb:3PGW|rcsb pdb:4F7U|rcsb pdb:4PJO|rcsb pdb:4V98|rcsb pdb:4WZJ|rcsb pdb:5MQF|rcsb pdb:5O9Z|rcsb pdb:5XJC|rcsb pdb:5XJL|rcsb pdb:5XJQ|rcsb pdb:5XJR|rcsb pdb:5XJT|rcsb pdb:5XJU|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|go:"GO:1990904"(ribonucleoprotein complex)|rcsb pdb:6AHD|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|refseq:NP_003087.1|dip:DIP-34627N refseq:NP_079051.9|dip:DIP-41331N|ensembl:ENSG00000152147(gene)|ensembl:ENST00000281950(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|go:"GO:0032797"(SMN complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0097504"(Gemini of coiled bodies)|interpro:IPR009422(Gemin6)|mint:Q8WXD5|rcsb pdb:1Y96|rcsb pdb:7BBL|reactome:R-HSA-191859 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/04 2017/08/10 rogid:bwbnMaq7QstuUpgUyJtFqzF5J/I9606 rogid:AaQyOsKgOMpkny7dYKmgwu0/c1g9606 rigid:UBzGR/xQg9oLoGVTveJGk2xGWUU false - glutathione s tranferase tag:n-n - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:Q9H840 uniprotkb:Q8WXD5 intact:EBI-715455|uniprotkb:Q6IA34|ensembl:ENSP00000375813|ensembl:ENSP00000465704|ensembl:ENSP00000466342|ensembl:ENSP00000270257 intact:EBI-752301|uniprotkb:Q53SI5|uniprotkb:Q8WVB4|uniprotkb:Q9H5G6|uniprotkb:B2RDP8|ensembl:ENSP00000281950 psi-mi:gemi7_human(display_long)|uniprotkb:SIP3(gene name synonym)|uniprotkb:GEMIN7(gene name)|psi-mi:GEMIN7(display_short) psi-mi:gemi6_human(display_long)|uniprotkb:SIP2(gene name synonym)|uniprotkb:GEMIN6(gene name)|psi-mi:GEMIN6(display_short) psi-mi:"MI:0096"(pull down) Ma et al. (2005) pubmed:15939020|doi:10.1016/j.str.2005.03.014|imex:IM-14201 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15552916|imex:IM-14201-2|dip:DIP-71041E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_005259319.1|refseq:XP_005259320.1|refseq:NP_001007270.1|refseq:NP_001007271.1|refseq:NP_078983.1|ensembl:ENSG00000142252(gene)|ensembl:ENST00000270257(transcript)|ensembl:ENST00000391951(transcript)|ensembl:ENST00000591607(transcript)|ensembl:ENST00000591747(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|go:"GO:0032797"(SMN complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0097504"(Gemini of coiled bodies)|go:"GO:0120114"(Sm-like protein family complex)|interpro:IPR020338|interpro:IPR024642|mint:Q9H840|rcsb pdb:1Y96|rcsb pdb:7BBL|reactome:R-HSA-191859|refseq:NP_001305983.1|refseq:NP_001305984.1|refseq:XP_016882801.1|dip:DIP-41750N refseq:NP_079051.9|dip:DIP-41331N|ensembl:ENSG00000152147(gene)|ensembl:ENST00000281950(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|go:"GO:0032797"(SMN complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0097504"(Gemini of coiled bodies)|interpro:IPR009422(Gemin6)|mint:Q8WXD5|rcsb pdb:1Y96|rcsb pdb:7BBL|reactome:R-HSA-191859 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/04 2017/08/10 rogid:jnNKbzuQxiIWKDmv7+je9B5U81Q9606 rogid:AaQyOsKgOMpkny7dYKmgwu0/c1g9606 rigid:LYSL0nwZ0RHQjHdRej0FHExESss false binding-associated region:31-131|his tag:n-n glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P62314 uniprotkb:Q8WXD5 intact:EBI-372177|uniprotkb:P13641|uniprotkb:B5BTZ1|ensembl:ENSP00000300413 intact:EBI-752301|uniprotkb:Q53SI5|uniprotkb:Q8WVB4|uniprotkb:Q9H5G6|uniprotkb:B2RDP8|ensembl:ENSP00000281950 psi-mi:smd1_human(display_long)|uniprotkb:SNRPD1(gene name)|psi-mi:SNRPD1(display_short)|uniprotkb:snRNP core protein D1(gene name synonym)|uniprotkb:Sm-D autoantigen(gene name synonym) psi-mi:gemi6_human(display_long)|uniprotkb:SIP2(gene name synonym)|uniprotkb:GEMIN6(gene name)|psi-mi:GEMIN6(display_short) psi-mi:"MI:0096"(pull down) Ma et al. (2005) pubmed:15939020|doi:10.1016/j.str.2005.03.014|imex:IM-14201 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15552958|imex:IM-14201-4|dip:DIP-102911E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001278845.1|refseq:NP_008869.1|ensembl:ENSG00000167088(gene)|ensembl:ENST00000300413(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0008380"(RNA splicing)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0034709"(methylosome)|go:"GO:0034715"(pICln-Sm protein complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0097526"(spliceosomal tri-snRNP complex)|go:"GO:1990446"(U1 snRNP binding)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|go:"GO:0000243"(commitment complex)|interpro:IPR027141|interpro:IPR034102|mint:P62314|rcsb pdb:1B34|rcsb pdb:3CW1|rcsb pdb:3JCR|rcsb pdb:3PGW|rcsb pdb:4F7U|rcsb pdb:4PJO|go:"GO:0000245"(spliceosomal complex assembly)|rcsb pdb:4V98|rcsb pdb:4WZJ|rcsb pdb:5MQF|rcsb pdb:5O9Z|rcsb pdb:5XJC|rcsb pdb:5XJL|rcsb pdb:5XJQ|go:"GO:0000387"(spliceosomal snRNP assembly)|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7A5P|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7B0Y|rcsb pdb:7DVQ|reactome:R-HSA-191859|reactome:R-HSA-72163|reactome:R-HSA-72165|dip:DIP-31207N refseq:NP_079051.9|dip:DIP-41331N|ensembl:ENSG00000152147(gene)|ensembl:ENST00000281950(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|go:"GO:0032797"(SMN complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0097504"(Gemini of coiled bodies)|interpro:IPR009422(Gemin6)|mint:Q8WXD5|rcsb pdb:1Y96|rcsb pdb:7BBL|reactome:R-HSA-191859 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/04 2017/08/10 rogid:bfXwsV+IOjDPCoOJOoMQgECyiII9606 rogid:AaQyOsKgOMpkny7dYKmgwu0/c1g9606 rigid:0xfbKZTP/u+Fs/zurGzabfYHMFs false - glutathione s tranferase tag:n-n - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:P62318 uniprotkb:Q8WXD5 intact:EBI-372789|uniprotkb:P43331|uniprotkb:B5BU13|uniprotkb:B4DJP7|ensembl:ENSP00000215829|intact:EBI-10981086 intact:EBI-752301|uniprotkb:Q53SI5|uniprotkb:Q8WVB4|uniprotkb:Q9H5G6|uniprotkb:B2RDP8|ensembl:ENSP00000281950 psi-mi:smd3_human(display_long)|uniprotkb:SNRPD3(gene name)|psi-mi:SNRPD3(display_short)|uniprotkb:snRNP core protein D3(gene name synonym) psi-mi:gemi6_human(display_long)|uniprotkb:SIP2(gene name synonym)|uniprotkb:GEMIN6(gene name)|psi-mi:GEMIN6(display_short) psi-mi:"MI:0096"(pull down) Ma et al. (2005) pubmed:15939020|doi:10.1016/j.str.2005.03.014|imex:IM-14201 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15552977|imex:IM-14201-5|dip:DIP-70159E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004166.1|refseq:NP_001265585.1|ensembl:ENSG00000100028(gene)|ensembl:ENST00000215829(transcript)|go:"GO:0000243"(commitment complex)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005683"(U7 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005829"(cytosol)|go:"GO:0006479"(protein methylation)|go:"GO:0008380"(RNA splicing)|go:"GO:0016604"(nuclear body)|go:"GO:0019899"(enzyme binding)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0034709"(methylosome)|go:"GO:0034715"(pICln-Sm protein complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071208"(histone pre-mRNA DCP binding)|go:"GO:0071209"(U7 snRNA binding)|go:"GO:0097526"(spliceosomal tri-snRNP complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027141|interpro:IPR034099|mint:P62318|rcsb pdb:1D3B|rcsb pdb:3CW1|rcsb pdb:3JCR|rcsb pdb:7ABI|rcsb pdb:7B0Y|rcsb pdb:7DVQ|reactome:R-HSA-111367|reactome:R-HSA-191859|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-73856|reactome:R-HSA-77588|rcsb pdb:7ABG|rcsb pdb:3VRI|rcsb pdb:4PJO|rcsb pdb:4WZJ|rcsb pdb:5MQF|rcsb pdb:5O9Z|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF7|rcsb pdb:3PGW|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:6V4X|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7A5P|dip:DIP-31216N refseq:NP_079051.9|dip:DIP-41331N|ensembl:ENSG00000152147(gene)|ensembl:ENST00000281950(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|go:"GO:0032797"(SMN complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0097504"(Gemini of coiled bodies)|interpro:IPR009422(Gemin6)|mint:Q8WXD5|rcsb pdb:1Y96|rcsb pdb:7BBL|reactome:R-HSA-191859 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/04 2017/08/10 rogid:WkrSZVfVmSQrJYfy7mwp48xjsVA9606 rogid:AaQyOsKgOMpkny7dYKmgwu0/c1g9606 rigid:VljF/hZC9XtEvjrTvRgu3YcnZt8 false - glutathione s tranferase tag:n-n - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:P62304 uniprotkb:Q8WXD5 intact:EBI-348082|ensembl:ENSP00000400591|uniprotkb:P08578|uniprotkb:Q15498|uniprotkb:Q5BKT2|uniprotkb:B2R5B9 intact:EBI-752301|uniprotkb:Q53SI5|uniprotkb:Q8WVB4|uniprotkb:Q9H5G6|uniprotkb:B2RDP8|ensembl:ENSP00000281950 psi-mi:ruxe_human(display_long)|uniprotkb:SNRPE(gene name)|psi-mi:SNRPE(display_short)|uniprotkb:Sm protein E(gene name synonym) psi-mi:gemi6_human(display_long)|uniprotkb:SIP2(gene name synonym)|uniprotkb:GEMIN6(gene name)|psi-mi:GEMIN6(display_short) psi-mi:"MI:0096"(pull down) Ma et al. (2005) pubmed:15939020|doi:10.1016/j.str.2005.03.014|imex:IM-14201 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15552996|imex:IM-14201-6|dip:DIP-70160E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000182004(gene)|ensembl:ENST00000414487(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005683"(U7 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005829"(cytosol)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0034709"(methylosome)|go:"GO:0034715"(pICln-Sm protein complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0042633"(hair cycle)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027078|mint:P62304|rcsb pdb:3CW1|rcsb pdb:3JCR|rcsb pdb:3PGW|rcsb pdb:4F7U|rcsb pdb:4PJO|rcsb pdb:4V98|rcsb pdb:4WZJ|rcsb pdb:5MQF|rcsb pdb:5O9Z|rcsb pdb:5XJC|rcsb pdb:5XJL|rcsb pdb:5XJQ|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:6V4X|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7A5P|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7B0Y|rcsb pdb:7DVQ|reactome:R-HSA-111367|reactome:R-HSA-191859|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-73856|reactome:R-HSA-77588|refseq:NP_003085.1|refseq:NP_001291393.1|refseq:NP_001315566.1|refseq:NP_001315567.1|dip:DIP-31220N refseq:NP_079051.9|dip:DIP-41331N|ensembl:ENSG00000152147(gene)|ensembl:ENST00000281950(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|go:"GO:0032797"(SMN complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0097504"(Gemini of coiled bodies)|interpro:IPR009422(Gemin6)|mint:Q8WXD5|rcsb pdb:1Y96|rcsb pdb:7BBL|reactome:R-HSA-191859 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/04 2017/08/10 rogid:QZ2/v8M+4+8AfWLPYNQO81/IeN09606 rogid:AaQyOsKgOMpkny7dYKmgwu0/c1g9606 rigid:EwUshFyoGNNurljRnCY/p96KJFE false - glutathione s tranferase tag:n-n - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:Q9H840 uniprotkb:Q8WXD5 intact:EBI-715455|uniprotkb:Q6IA34|ensembl:ENSP00000375813|ensembl:ENSP00000465704|ensembl:ENSP00000466342|ensembl:ENSP00000270257 intact:EBI-752301|uniprotkb:Q53SI5|uniprotkb:Q8WVB4|uniprotkb:Q9H5G6|uniprotkb:B2RDP8|ensembl:ENSP00000281950 psi-mi:gemi7_human(display_long)|uniprotkb:SIP3(gene name synonym)|uniprotkb:GEMIN7(gene name)|psi-mi:GEMIN7(display_short) psi-mi:gemi6_human(display_long)|uniprotkb:SIP2(gene name synonym)|uniprotkb:GEMIN6(gene name)|psi-mi:GEMIN6(display_short) psi-mi:"MI:0028"(cosedimentation in solution) Ma et al. (2005) pubmed:15939020|doi:10.1016/j.str.2005.03.014|imex:IM-14201 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15553015|imex:IM-14201-7|dip:DIP-71041E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_005259319.1|refseq:XP_005259320.1|refseq:NP_001007270.1|refseq:NP_001007271.1|refseq:NP_078983.1|ensembl:ENSG00000142252(gene)|ensembl:ENST00000270257(transcript)|ensembl:ENST00000391951(transcript)|ensembl:ENST00000591607(transcript)|ensembl:ENST00000591747(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|go:"GO:0032797"(SMN complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0097504"(Gemini of coiled bodies)|go:"GO:0120114"(Sm-like protein family complex)|interpro:IPR020338|interpro:IPR024642|mint:Q9H840|rcsb pdb:1Y96|rcsb pdb:7BBL|reactome:R-HSA-191859|refseq:NP_001305983.1|refseq:NP_001305984.1|refseq:XP_016882801.1|dip:DIP-41750N refseq:NP_079051.9|dip:DIP-41331N|ensembl:ENSG00000152147(gene)|ensembl:ENST00000281950(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|go:"GO:0032797"(SMN complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0097504"(Gemini of coiled bodies)|interpro:IPR009422(Gemin6)|mint:Q8WXD5|rcsb pdb:1Y96|rcsb pdb:7BBL|reactome:R-HSA-191859 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/04 2017/08/10 rogid:jnNKbzuQxiIWKDmv7+je9B5U81Q9606 rogid:AaQyOsKgOMpkny7dYKmgwu0/c1g9606 rigid:LYSL0nwZ0RHQjHdRej0FHExESss false binding-associated region:31-131 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H840 uniprotkb:Q8WXD5 intact:EBI-715455|uniprotkb:Q6IA34|ensembl:ENSP00000375813|ensembl:ENSP00000465704|ensembl:ENSP00000466342|ensembl:ENSP00000270257 intact:EBI-752301|uniprotkb:Q53SI5|uniprotkb:Q8WVB4|uniprotkb:Q9H5G6|uniprotkb:B2RDP8|ensembl:ENSP00000281950 psi-mi:gemi7_human(display_long)|uniprotkb:SIP3(gene name synonym)|uniprotkb:GEMIN7(gene name)|psi-mi:GEMIN7(display_short) psi-mi:gemi6_human(display_long)|uniprotkb:SIP2(gene name synonym)|uniprotkb:GEMIN6(gene name)|psi-mi:GEMIN6(display_short) psi-mi:"MI:0071"(molecular sieving) Ma et al. (2005) pubmed:15939020|doi:10.1016/j.str.2005.03.014|imex:IM-14201 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15553034|imex:IM-14201-8|dip:DIP-71041E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_005259319.1|refseq:XP_005259320.1|refseq:NP_001007270.1|refseq:NP_001007271.1|refseq:NP_078983.1|ensembl:ENSG00000142252(gene)|ensembl:ENST00000270257(transcript)|ensembl:ENST00000391951(transcript)|ensembl:ENST00000591607(transcript)|ensembl:ENST00000591747(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|go:"GO:0032797"(SMN complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0097504"(Gemini of coiled bodies)|go:"GO:0120114"(Sm-like protein family complex)|interpro:IPR020338|interpro:IPR024642|mint:Q9H840|rcsb pdb:1Y96|rcsb pdb:7BBL|reactome:R-HSA-191859|refseq:NP_001305983.1|refseq:NP_001305984.1|refseq:XP_016882801.1|dip:DIP-41750N refseq:NP_079051.9|dip:DIP-41331N|ensembl:ENSG00000152147(gene)|ensembl:ENST00000281950(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|go:"GO:0032797"(SMN complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0097504"(Gemini of coiled bodies)|interpro:IPR009422(Gemin6)|mint:Q8WXD5|rcsb pdb:1Y96|rcsb pdb:7BBL|reactome:R-HSA-191859 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/04 2017/08/10 rogid:jnNKbzuQxiIWKDmv7+je9B5U81Q9606 rogid:AaQyOsKgOMpkny7dYKmgwu0/c1g9606 rigid:LYSL0nwZ0RHQjHdRej0FHExESss false binding-associated region:31-131 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P62306 uniprotkb:Q8WXD5 intact:EBI-356900|uniprotkb:A2VCR2|uniprotkb:Q15356|uniprotkb:Q6IBQ1|uniprotkb:Q6P4I0|uniprotkb:B2R498|ensembl:ENSP00000266735 intact:EBI-752301|uniprotkb:Q53SI5|uniprotkb:Q8WVB4|uniprotkb:Q9H5G6|uniprotkb:B2RDP8|ensembl:ENSP00000281950 psi-mi:ruxf_human(display_long)|uniprotkb:SNRPF(gene name)|psi-mi:SNRPF(display_short)|uniprotkb:PBSCF(gene name synonym)|uniprotkb:Sm protein F(gene name synonym) psi-mi:gemi6_human(display_long)|uniprotkb:SIP2(gene name synonym)|uniprotkb:GEMIN6(gene name)|psi-mi:GEMIN6(display_short) psi-mi:"MI:0096"(pull down) Ma et al. (2005) pubmed:15939020|doi:10.1016/j.str.2005.03.014|imex:IM-14201 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15553093|imex:IM-14201-11|dip:DIP-102912E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003086.1|ensembl:ENSG00000139343(gene)|ensembl:ENST00000266735(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005683"(U7 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0008380"(RNA splicing)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0034709"(methylosome)|go:"GO:0034715"(pICln-Sm protein complex)|go:"GO:0034719"(SMN-Sm protein complex)|dip:DIP-31221N|rcsb pdb:5XJL|rcsb pdb:5XJQ|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:6V4X|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7A5P|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7B0Y|rcsb pdb:7DVQ|reactome:R-HSA-111367|reactome:R-HSA-191859|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-73856|reactome:R-HSA-77588|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR016487(Small nuclear ribonucleoprotein SmF)|interpro:IPR034100|mint:P62306|rcsb pdb:3CW1|rcsb pdb:3JCR|rcsb pdb:3PGW|rcsb pdb:4F7U|rcsb pdb:4PJO|rcsb pdb:4V98|rcsb pdb:4WZJ|rcsb pdb:5MQF|rcsb pdb:5O9Z|rcsb pdb:5XJC refseq:NP_079051.9|dip:DIP-41331N|ensembl:ENSG00000152147(gene)|ensembl:ENST00000281950(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|go:"GO:0032797"(SMN complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0097504"(Gemini of coiled bodies)|interpro:IPR009422(Gemin6)|mint:Q8WXD5|rcsb pdb:1Y96|rcsb pdb:7BBL|reactome:R-HSA-191859 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/04 2017/08/10 rogid:2RggXu+kFj6wG7gTmxRHOIRvXiM9606 rogid:AaQyOsKgOMpkny7dYKmgwu0/c1g9606 rigid:qwG8wyDzQ+CBlkvXivyTKT+AFJc false - glutathione s tranferase tag:n-n - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:P62314 uniprotkb:Q8WXD5 intact:EBI-372177|uniprotkb:P13641|uniprotkb:B5BTZ1|ensembl:ENSP00000300413 intact:EBI-752301|uniprotkb:Q53SI5|uniprotkb:Q8WVB4|uniprotkb:Q9H5G6|uniprotkb:B2RDP8|ensembl:ENSP00000281950 psi-mi:smd1_human(display_long)|uniprotkb:SNRPD1(gene name)|psi-mi:SNRPD1(display_short)|uniprotkb:snRNP core protein D1(gene name synonym)|uniprotkb:Sm-D autoantigen(gene name synonym) psi-mi:gemi6_human(display_long)|uniprotkb:SIP2(gene name synonym)|uniprotkb:GEMIN6(gene name)|psi-mi:GEMIN6(display_short) psi-mi:"MI:0096"(pull down) Ma et al. (2005) pubmed:15939020|doi:10.1016/j.str.2005.03.014|imex:IM-14201 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15553072|imex:IM-14201-10|dip:DIP-102911E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001278845.1|refseq:NP_008869.1|ensembl:ENSG00000167088(gene)|ensembl:ENST00000300413(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0008380"(RNA splicing)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0034709"(methylosome)|go:"GO:0034715"(pICln-Sm protein complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0097526"(spliceosomal tri-snRNP complex)|go:"GO:1990446"(U1 snRNP binding)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|go:"GO:0000243"(commitment complex)|interpro:IPR027141|interpro:IPR034102|mint:P62314|rcsb pdb:1B34|rcsb pdb:3CW1|rcsb pdb:3JCR|rcsb pdb:3PGW|rcsb pdb:4F7U|rcsb pdb:4PJO|go:"GO:0000245"(spliceosomal complex assembly)|rcsb pdb:4V98|rcsb pdb:4WZJ|rcsb pdb:5MQF|rcsb pdb:5O9Z|rcsb pdb:5XJC|rcsb pdb:5XJL|rcsb pdb:5XJQ|go:"GO:0000387"(spliceosomal snRNP assembly)|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7A5P|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7B0Y|rcsb pdb:7DVQ|reactome:R-HSA-191859|reactome:R-HSA-72163|reactome:R-HSA-72165|dip:DIP-31207N refseq:NP_079051.9|dip:DIP-41331N|ensembl:ENSG00000152147(gene)|ensembl:ENST00000281950(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|go:"GO:0032797"(SMN complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0097504"(Gemini of coiled bodies)|interpro:IPR009422(Gemin6)|mint:Q8WXD5|rcsb pdb:1Y96|rcsb pdb:7BBL|reactome:R-HSA-191859 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/04 2017/08/10 rogid:bfXwsV+IOjDPCoOJOoMQgECyiII9606 rogid:AaQyOsKgOMpkny7dYKmgwu0/c1g9606 rigid:0xfbKZTP/u+Fs/zurGzabfYHMFs false his tag:n-n glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P62316 uniprotkb:Q8WXD5 intact:EBI-297993|uniprotkb:P43330|ensembl:ENSP00000342374|ensembl:ENSP00000465216|uniprotkb:A8K797|uniprotkb:J3KPM5 intact:EBI-752301|uniprotkb:Q53SI5|uniprotkb:Q8WVB4|uniprotkb:Q9H5G6|uniprotkb:B2RDP8|ensembl:ENSP00000281950 psi-mi:smd2_human(display_long)|uniprotkb:SNRPD2(gene name)|psi-mi:SNRPD2(display_short)|uniprotkb:snRNP core protein D2(gene name synonym)|uniprotkb:SNRPD1(gene name synonym) psi-mi:gemi6_human(display_long)|uniprotkb:SIP2(gene name synonym)|uniprotkb:GEMIN6(gene name)|psi-mi:GEMIN6(display_short) psi-mi:"MI:0096"(pull down) Ma et al. (2005) pubmed:15939020|doi:10.1016/j.str.2005.03.014|imex:IM-14201 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15553053|imex:IM-14201-9|dip:DIP-70158E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000125743(gene)|ensembl:ENST00000342669(transcript)|ensembl:ENST00000588301(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0008380"(RNA splicing)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0034709"(methylosome)|go:"GO:0034715"(pICln-Sm protein complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990446"(U1 snRNP binding)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027248|mint:P62316|rcsb pdb:1B34|rcsb pdb:3CW1|rcsb pdb:3JCR|rcsb pdb:3PGW|rcsb pdb:4F7U|rcsb pdb:4PJO|rcsb pdb:4V98|rcsb pdb:4WZJ|rcsb pdb:5MQF|rcsb pdb:5O9Z|rcsb pdb:5XJC|rcsb pdb:5XJL|rcsb pdb:5XJQ|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7A5P|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7B0Y|rcsb pdb:7DVQ|reactome:R-HSA-191859|reactome:R-HSA-72163|reactome:R-HSA-72165|refseq:NP_004588.1|refseq:NP_808210.2|dip:DIP-31219N refseq:NP_079051.9|dip:DIP-41331N|ensembl:ENSG00000152147(gene)|ensembl:ENST00000281950(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|go:"GO:0032797"(SMN complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0097504"(Gemini of coiled bodies)|interpro:IPR009422(Gemin6)|mint:Q8WXD5|rcsb pdb:1Y96|rcsb pdb:7BBL|reactome:R-HSA-191859 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/04 2017/08/10 rogid:4OshNPT6N4dOcWMVXrF5Fm8dcnI9606 rogid:AaQyOsKgOMpkny7dYKmgwu0/c1g9606 rigid:eX3w3pHvqcDROdFmgAf9u4gL/so false - glutathione s tranferase tag:n-n - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:P14678-2 uniprotkb:Q8WXD5 intact:EBI-372475|ensembl:ENSP00000370746|intact:EBI-7175726|intact:MINT-124911|intact:EBI-7176920 intact:EBI-752301|uniprotkb:Q53SI5|uniprotkb:Q8WVB4|uniprotkb:Q9H5G6|uniprotkb:B2RDP8|ensembl:ENSP00000281950 psi-mi:p14678-2(display_long)|uniprotkb:SNRPB(gene name)|psi-mi:SNRPB(display_short)|uniprotkb:COD(gene name synonym)|uniprotkb:SNRPB1(gene name synonym)|uniprotkb:Sm protein B/B'(gene name synonym) psi-mi:gemi6_human(display_long)|uniprotkb:SIP2(gene name synonym)|uniprotkb:GEMIN6(gene name)|psi-mi:GEMIN6(display_short) psi-mi:"MI:0096"(pull down) Ma et al. (2005) pubmed:15939020|doi:10.1016/j.str.2005.03.014|imex:IM-14201 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15553112|imex:IM-14201-12|dip:DIP-70157E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-372458(rsmb_human)|ensembl:ENSG00000125835(gene)|ensembl:ENST00000381342(transcript)|uniprotkb:P14678-2(isoform-parent) refseq:NP_079051.9|dip:DIP-41331N|ensembl:ENSG00000152147(gene)|ensembl:ENST00000281950(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|go:"GO:0032797"(SMN complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0097504"(Gemini of coiled bodies)|interpro:IPR009422(Gemin6)|mint:Q8WXD5|rcsb pdb:1Y96|rcsb pdb:7BBL|reactome:R-HSA-191859 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/04 2017/08/10 rogid:4YLKg8JREkaZmS2RL+o/Sxtl7rw9606 rogid:AaQyOsKgOMpkny7dYKmgwu0/c1g9606 rigid:1Wnn31PtSRChVkFQGs4/D5pn3fE false - glutathione s tranferase tag:n-n - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography)