#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:O05207	uniprotkb:O05207	intact:EBI-9026762	intact:EBI-9026762	psi-mi:top6b_sacsh(display_long)|uniprotkb:top6B(gene name)|psi-mi:top6B(display_short)|uniprotkb:Type II DNA topoisomerase VI subunit B(gene name synonym)	psi-mi:top6b_sacsh(display_long)|uniprotkb:top6B(gene name)|psi-mi:top6B(display_short)|uniprotkb:Type II DNA topoisomerase VI subunit B(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Corbett et al. (2005)	pubmed:15939019|doi:10.1016/j.str.2005.03.013|imex:IM-14200	taxid:2286(sulsh)|taxid:2286(Sulfolobus shibatae)	taxid:2286(sulsh)|taxid:2286(Sulfolobus shibatae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15552849|imex:IM-14200-1|dip:DIP-58786E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-29416N|go:"GO:0003677"(DNA binding)|go:"GO:0003918"("DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0006265"(DNA topological change)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0009330"("DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex")|go:"GO:0042802"(identical protein binding)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR005734(DNA topoisomerase VI, subunit B)|interpro:IPR010979(Ribosomal protein S13-like, H2TH)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR015320(DNA topoisomerase VI, subunit B, transducer)|interpro:IPR020568|interpro:IPR036890|rcsb pdb:1MU5|rcsb pdb:1MX0|rcsb pdb:1Z59|rcsb pdb:1Z5A|rcsb pdb:1Z5B|rcsb pdb:1Z5C|rcsb pdb:2HKJ|rcsb pdb:2ZBK	dip:DIP-29416N|go:"GO:0003677"(DNA binding)|go:"GO:0003918"("DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0006265"(DNA topological change)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0009330"("DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex")|go:"GO:0042802"(identical protein binding)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR005734(DNA topoisomerase VI, subunit B)|interpro:IPR010979(Ribosomal protein S13-like, H2TH)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR015320(DNA topoisomerase VI, subunit B, transducer)|interpro:IPR020568|interpro:IPR036890|rcsb pdb:1MU5|rcsb pdb:1MX0|rcsb pdb:1Z59|rcsb pdb:1Z5A|rcsb pdb:1Z5B|rcsb pdb:1Z5C|rcsb pdb:2HKJ|rcsb pdb:2ZBK	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/04	2017/08/10	rogid:bxfNiocOEI1pthPZNOM5aPKToko2286	rogid:bxfNiocOEI1pthPZNOM5aPKToko2286	rigid:z/4ne13M5GqFMDwi2xUI1FxTG5o	false	binding-associated region:2-470	binding-associated region:2-470	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O05207	uniprotkb:O05207	intact:EBI-9026762	intact:EBI-9026762	psi-mi:top6b_sacsh(display_long)|uniprotkb:top6B(gene name)|psi-mi:top6B(display_short)|uniprotkb:Type II DNA topoisomerase VI subunit B(gene name synonym)	psi-mi:top6b_sacsh(display_long)|uniprotkb:top6B(gene name)|psi-mi:top6B(display_short)|uniprotkb:Type II DNA topoisomerase VI subunit B(gene name synonym)	psi-mi:"MI:0030"(cross-linking study)	Corbett et al. (2005)	pubmed:15939019|doi:10.1016/j.str.2005.03.013|imex:IM-14200	taxid:2286(sulsh)|taxid:2286(Sulfolobus shibatae)	taxid:2286(sulsh)|taxid:2286(Sulfolobus shibatae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15552867|imex:IM-14200-2|dip:DIP-58786E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-29416N|go:"GO:0003677"(DNA binding)|go:"GO:0003918"("DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0006265"(DNA topological change)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0009330"("DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex")|go:"GO:0042802"(identical protein binding)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR005734(DNA topoisomerase VI, subunit B)|interpro:IPR010979(Ribosomal protein S13-like, H2TH)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR015320(DNA topoisomerase VI, subunit B, transducer)|interpro:IPR020568|interpro:IPR036890|rcsb pdb:1MU5|rcsb pdb:1MX0|rcsb pdb:1Z59|rcsb pdb:1Z5A|rcsb pdb:1Z5B|rcsb pdb:1Z5C|rcsb pdb:2HKJ|rcsb pdb:2ZBK	dip:DIP-29416N|go:"GO:0003677"(DNA binding)|go:"GO:0003918"("DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0006265"(DNA topological change)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0009330"("DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex")|go:"GO:0042802"(identical protein binding)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR005734(DNA topoisomerase VI, subunit B)|interpro:IPR010979(Ribosomal protein S13-like, H2TH)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR015320(DNA topoisomerase VI, subunit B, transducer)|interpro:IPR020568|interpro:IPR036890|rcsb pdb:1MU5|rcsb pdb:1MX0|rcsb pdb:1Z59|rcsb pdb:1Z5A|rcsb pdb:1Z5B|rcsb pdb:1Z5C|rcsb pdb:2HKJ|rcsb pdb:2ZBK	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/04	2017/08/10	rogid:bxfNiocOEI1pthPZNOM5aPKToko2286	rogid:bxfNiocOEI1pthPZNOM5aPKToko2286	rigid:z/4ne13M5GqFMDwi2xUI1FxTG5o	false	binding-associated region:2-470	binding-associated region:2-470	-	0	psi-mi:"MI:0816"(molecular weight estimation by staining)	psi-mi:"MI:0816"(molecular weight estimation by staining)