#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9VJY9 uniprotkb:Q9VCU9 intact:EBI-638074|ensemblmetazoa:FBpp0080076|uniprotkb:Q8SZ74 intact:EBI-112170|uniprotkb:Q961S7|ensemblmetazoa:FBpp0083717 psi-mi:q9vjy9_drome(display_long)|uniprotkb:loqs(gene name)|psi-mi:loqs(display_short)|uniprotkb:Loqs-PD(gene name synonym)|uniprotkb:LqPD(gene name synonym)|uniprotkb:Dmel\CG6866(gene name synonym)|uniprotkb:LOQS(gene name synonym)|uniprotkb:Loqs(gene name synonym)|uniprotkb:R3D1(gene name synonym)|uniprotkb:R3D1-L(gene name synonym)|uniprotkb:R3D1-S(gene name synonym)|uniprotkb:TRBP(gene name synonym)|uniprotkb:dRax(gene name synonym)|uniprotkb:loq(gene name synonym)|uniprotkb:r3d1(gene name synonym)|uniprotkb:Dmel_CG6866(orf name)|uniprotkb:cg6866(gene name synonym)|uniprotkb:CG6866(orf name) psi-mi:dcr1_drome(display_long)|uniprotkb:Dcr-1(gene name)|psi-mi:Dcr-1(display_short)|uniprotkb:CG4792(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Förstemann et al. (2005) pubmed:15918770|doi:10.1371/journal.pbio.0030236|imex:IM-9330 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15552660|imex:IM-9330-1|dip:DIP-87846E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0032515(gene)|ensemblmetazoa:FBtr0080498(transcript)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007417"(central nervous system development)|go:"GO:0009047"(dosage compensation by hyperactivation of X chromosome)|go:"GO:0010586"(miRNA metabolic process)|go:"GO:0030422"(production of siRNA involved in RNA interference)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0035087"(siRNA loading onto RISC involved in RNA interference)|go:"GO:0035197"(siRNA binding)|go:"GO:0048132"(female germ-line stem cell asymmetric division)|refseq:NP_609646.1|flybase:FBgn0032515|go:"GO:0070578"(RISC-loading complex)|go:"GO:0070877"(microprocessor complex)|go:"GO:0070918"(primary sncRNA processing)|go:"GO:0070920"(regulation of production of small RNA involved in gene silencing by RNA)|go:"GO:1905172"(RISC complex binding)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR032478|rcsb pdb:4X8W|reactome:R-DME-203927|reactome:R-DME-426486|dip:DIP-18138N refseq:NP_524453.1|flybase:FBgn0039016|dip:DIP-23028N|ensemblmetazoa:FBgn0039016(gene)|ensemblmetazoa:FBtr0084324(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0004525"(ribonuclease III activity)|go:"GO:0004530"(deoxyribonuclease I activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006309"(apoptotic DNA fragmentation)|go:"GO:0007279"(pole cell formation)|go:"GO:0007294"(germarium-derived oocyte fate determination)|go:"GO:0007367"(segment polarity determination)|go:"GO:0016246"(RNA interference)|go:"GO:0016442"(RISC complex)|go:"GO:0016443"(bidentate ribonuclease III activity)|go:"GO:0030422"(production of siRNA involved in RNA interference)|go:"GO:0030727"(germarium-derived female germ-line cyst formation)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0033227"(dsRNA transport)|go:"GO:0035087"(siRNA loading onto RISC involved in RNA interference)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0042078"(germ-line stem cell division)|go:"GO:0042594"(response to starvation)|go:"GO:0045448"(mitotic cell cycle, embryonic)|go:"GO:0046872"(metal ion binding)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0070578"(RISC-loading complex)|go:"GO:0070883"(pre-miRNA binding)|go:"GO:0090501"(RNA phosphodiester bond hydrolysis)|interpro:IPR000999(Ribonuclease III)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR003100(Argonaute and Dicer protein, PAZ)|interpro:IPR005034(Protein of unknown function DUF283)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR027417|interpro:IPR036085|interpro:IPR036389|interpro:IPR038248|interpro:IPR044441|reactome:R-DME-203927|reactome:R-DME-426486 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2017/08/04 2017/08/10 rogid:b4hUTrpZAKdYrKrNXyii52Zz43Y7227 rogid:qQiK00k/1UZST/JWnD/HUdltS9w7227 rigid:DKU5emuACycx/C4Gj4aiayOiBu8 false myc tag:n-n - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9VCU9 uniprotkb:Q9VJY9 intact:EBI-112170|uniprotkb:Q961S7|ensemblmetazoa:FBpp0083717 intact:EBI-638074|ensemblmetazoa:FBpp0080076|uniprotkb:Q8SZ74 psi-mi:dcr1_drome(display_long)|uniprotkb:Dcr-1(gene name)|psi-mi:Dcr-1(display_short)|uniprotkb:CG4792(orf name) psi-mi:q9vjy9_drome(display_long)|uniprotkb:loqs(gene name)|psi-mi:loqs(display_short)|uniprotkb:Loqs-PD(gene name synonym)|uniprotkb:LqPD(gene name synonym)|uniprotkb:Dmel\CG6866(gene name synonym)|uniprotkb:LOQS(gene name synonym)|uniprotkb:Loqs(gene name synonym)|uniprotkb:R3D1(gene name synonym)|uniprotkb:R3D1-L(gene name synonym)|uniprotkb:R3D1-S(gene name synonym)|uniprotkb:TRBP(gene name synonym)|uniprotkb:dRax(gene name synonym)|uniprotkb:loq(gene name synonym)|uniprotkb:r3d1(gene name synonym)|uniprotkb:Dmel_CG6866(orf name)|uniprotkb:cg6866(gene name synonym)|uniprotkb:CG6866(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Förstemann et al. (2005) pubmed:15918770|doi:10.1371/journal.pbio.0030236|imex:IM-9330 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15552679|imex:IM-9330-4|dip:DIP-87844E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524453.1|flybase:FBgn0039016|dip:DIP-23028N|ensemblmetazoa:FBgn0039016(gene)|ensemblmetazoa:FBtr0084324(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0004525"(ribonuclease III activity)|go:"GO:0004530"(deoxyribonuclease I activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006309"(apoptotic DNA fragmentation)|go:"GO:0007279"(pole cell formation)|go:"GO:0007294"(germarium-derived oocyte fate determination)|go:"GO:0007367"(segment polarity determination)|go:"GO:0016246"(RNA interference)|go:"GO:0016442"(RISC complex)|go:"GO:0016443"(bidentate ribonuclease III activity)|go:"GO:0030422"(production of siRNA involved in RNA interference)|go:"GO:0030727"(germarium-derived female germ-line cyst formation)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0033227"(dsRNA transport)|go:"GO:0035087"(siRNA loading onto RISC involved in RNA interference)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0042078"(germ-line stem cell division)|go:"GO:0042594"(response to starvation)|go:"GO:0045448"(mitotic cell cycle, embryonic)|go:"GO:0046872"(metal ion binding)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0070578"(RISC-loading complex)|go:"GO:0070883"(pre-miRNA binding)|go:"GO:0090501"(RNA phosphodiester bond hydrolysis)|interpro:IPR000999(Ribonuclease III)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR003100(Argonaute and Dicer protein, PAZ)|interpro:IPR005034(Protein of unknown function DUF283)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR027417|interpro:IPR036085|interpro:IPR036389|interpro:IPR038248|interpro:IPR044441|reactome:R-DME-203927|reactome:R-DME-426486 ensemblmetazoa:FBgn0032515(gene)|ensemblmetazoa:FBtr0080498(transcript)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007417"(central nervous system development)|go:"GO:0009047"(dosage compensation by hyperactivation of X chromosome)|go:"GO:0010586"(miRNA metabolic process)|go:"GO:0030422"(production of siRNA involved in RNA interference)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0035087"(siRNA loading onto RISC involved in RNA interference)|go:"GO:0035197"(siRNA binding)|go:"GO:0048132"(female germ-line stem cell asymmetric division)|refseq:NP_609646.1|flybase:FBgn0032515|go:"GO:0070578"(RISC-loading complex)|go:"GO:0070877"(microprocessor complex)|go:"GO:0070918"(primary sncRNA processing)|go:"GO:0070920"(regulation of production of small RNA involved in gene silencing by RNA)|go:"GO:1905172"(RISC complex binding)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR032478|rcsb pdb:4X8W|reactome:R-DME-203927|reactome:R-DME-426486|dip:DIP-18138N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2017/08/04 2017/08/10 rogid:qQiK00k/1UZST/JWnD/HUdltS9w7227 rogid:b4hUTrpZAKdYrKrNXyii52Zz43Y7227 rigid:qWs2vyCMbzgK9Gz7wX7iza0sKRM false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9VCU9 uniprotkb:Q8IP72 intact:EBI-112170|uniprotkb:Q961S7|ensemblmetazoa:FBpp0083717 intact:EBI-162836|ensemblmetazoa:FBpp0080075 psi-mi:dcr1_drome(display_long)|uniprotkb:Dcr-1(gene name)|psi-mi:Dcr-1(display_short)|uniprotkb:CG4792(orf name) psi-mi:q8ip72_drome(display_long)|uniprotkb:loqs(gene name)|psi-mi:loqs(display_short)|uniprotkb:Dmel\CG6866(gene name synonym)|uniprotkb:LOQS(gene name synonym)|uniprotkb:Loqs(gene name synonym)|uniprotkb:R3D1(gene name synonym)|uniprotkb:R3D1-L(gene name synonym)|uniprotkb:R3D1-S(gene name synonym)|uniprotkb:TRBP(gene name synonym)|uniprotkb:dRax(gene name synonym)|uniprotkb:loq(gene name synonym)|uniprotkb:r3d1(gene name synonym)|uniprotkb:Dmel_CG6866(orf name)|uniprotkb:CG6866(orf name)|uniprotkb:cg6866(gene name synonym)|uniprotkb:Loqs-PD(gene name synonym)|uniprotkb:LqPD(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Förstemann et al. (2005) pubmed:15918770|doi:10.1371/journal.pbio.0030236|imex:IM-9330 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15552679|imex:IM-9330-4|dip:DIP-87844E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524453.1|flybase:FBgn0039016|dip:DIP-23028N|ensemblmetazoa:FBgn0039016(gene)|ensemblmetazoa:FBtr0084324(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0004525"(ribonuclease III activity)|go:"GO:0004530"(deoxyribonuclease I activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006309"(apoptotic DNA fragmentation)|go:"GO:0007279"(pole cell formation)|go:"GO:0007294"(germarium-derived oocyte fate determination)|go:"GO:0007367"(segment polarity determination)|go:"GO:0016246"(RNA interference)|go:"GO:0016442"(RISC complex)|go:"GO:0016443"(bidentate ribonuclease III activity)|go:"GO:0030422"(production of siRNA involved in RNA interference)|go:"GO:0030727"(germarium-derived female germ-line cyst formation)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0033227"(dsRNA transport)|go:"GO:0035087"(siRNA loading onto RISC involved in RNA interference)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0042078"(germ-line stem cell division)|go:"GO:0042594"(response to starvation)|go:"GO:0045448"(mitotic cell cycle, embryonic)|go:"GO:0046872"(metal ion binding)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0070578"(RISC-loading complex)|go:"GO:0070883"(pre-miRNA binding)|go:"GO:0090501"(RNA phosphodiester bond hydrolysis)|interpro:IPR000999(Ribonuclease III)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR003100(Argonaute and Dicer protein, PAZ)|interpro:IPR005034(Protein of unknown function DUF283)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR027417|interpro:IPR036085|interpro:IPR036389|interpro:IPR038248|interpro:IPR044441|reactome:R-DME-203927|reactome:R-DME-426486 refseq:NP_723813.1|flybase:FBgn0032515|ensemblmetazoa:FBgn0032515(gene)|ensemblmetazoa:FBtr0080497(transcript)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007417"(central nervous system development)|go:"GO:0009047"(dosage compensation by hyperactivation of X chromosome)|go:"GO:0010586"(miRNA metabolic process)|go:"GO:0030422"(production of siRNA involved in RNA interference)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0048132"(female germ-line stem cell asymmetric division)|go:"GO:0070918"(primary sncRNA processing)|go:"GO:0070920"(regulation of production of small RNA involved in gene silencing by RNA)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR032478|dip:DIP-46082N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2017/08/04 2017/08/10 rogid:qQiK00k/1UZST/JWnD/HUdltS9w7227 rogid:sK/JdnkQDPAuc6wJ1a0qlMg+LLQ7227 rigid:qWs2vyCMbzgK9Gz7wX7iza0sKRM false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9VJY9 uniprotkb:Q9VCU9 intact:EBI-638074|ensemblmetazoa:FBpp0080076|uniprotkb:Q8SZ74 intact:EBI-112170|uniprotkb:Q961S7|ensemblmetazoa:FBpp0083717 psi-mi:q9vjy9_drome(display_long)|uniprotkb:loqs(gene name)|psi-mi:loqs(display_short)|uniprotkb:Loqs-PD(gene name synonym)|uniprotkb:LqPD(gene name synonym)|uniprotkb:Dmel\CG6866(gene name synonym)|uniprotkb:LOQS(gene name synonym)|uniprotkb:Loqs(gene name synonym)|uniprotkb:R3D1(gene name synonym)|uniprotkb:R3D1-L(gene name synonym)|uniprotkb:R3D1-S(gene name synonym)|uniprotkb:TRBP(gene name synonym)|uniprotkb:dRax(gene name synonym)|uniprotkb:loq(gene name synonym)|uniprotkb:r3d1(gene name synonym)|uniprotkb:Dmel_CG6866(orf name)|uniprotkb:cg6866(gene name synonym)|uniprotkb:CG6866(orf name) psi-mi:dcr1_drome(display_long)|uniprotkb:Dcr-1(gene name)|psi-mi:Dcr-1(display_short)|uniprotkb:CG4792(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Förstemann et al. (2005) pubmed:15918770|doi:10.1371/journal.pbio.0030236|imex:IM-9330 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15552734|imex:IM-9330-2|dip:DIP-87846E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0032515(gene)|ensemblmetazoa:FBtr0080498(transcript)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007417"(central nervous system development)|go:"GO:0009047"(dosage compensation by hyperactivation of X chromosome)|go:"GO:0010586"(miRNA metabolic process)|go:"GO:0030422"(production of siRNA involved in RNA interference)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0035087"(siRNA loading onto RISC involved in RNA interference)|go:"GO:0035197"(siRNA binding)|go:"GO:0048132"(female germ-line stem cell asymmetric division)|refseq:NP_609646.1|flybase:FBgn0032515|go:"GO:0070578"(RISC-loading complex)|go:"GO:0070877"(microprocessor complex)|go:"GO:0070918"(primary sncRNA processing)|go:"GO:0070920"(regulation of production of small RNA involved in gene silencing by RNA)|go:"GO:1905172"(RISC complex binding)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR032478|rcsb pdb:4X8W|reactome:R-DME-203927|reactome:R-DME-426486|dip:DIP-18138N refseq:NP_524453.1|flybase:FBgn0039016|dip:DIP-23028N|ensemblmetazoa:FBgn0039016(gene)|ensemblmetazoa:FBtr0084324(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0004525"(ribonuclease III activity)|go:"GO:0004530"(deoxyribonuclease I activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006309"(apoptotic DNA fragmentation)|go:"GO:0007279"(pole cell formation)|go:"GO:0007294"(germarium-derived oocyte fate determination)|go:"GO:0007367"(segment polarity determination)|go:"GO:0016246"(RNA interference)|go:"GO:0016442"(RISC complex)|go:"GO:0016443"(bidentate ribonuclease III activity)|go:"GO:0030422"(production of siRNA involved in RNA interference)|go:"GO:0030727"(germarium-derived female germ-line cyst formation)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0033227"(dsRNA transport)|go:"GO:0035087"(siRNA loading onto RISC involved in RNA interference)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0042078"(germ-line stem cell division)|go:"GO:0042594"(response to starvation)|go:"GO:0045448"(mitotic cell cycle, embryonic)|go:"GO:0046872"(metal ion binding)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0070578"(RISC-loading complex)|go:"GO:0070883"(pre-miRNA binding)|go:"GO:0090501"(RNA phosphodiester bond hydrolysis)|interpro:IPR000999(Ribonuclease III)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR003100(Argonaute and Dicer protein, PAZ)|interpro:IPR005034(Protein of unknown function DUF283)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR027417|interpro:IPR036085|interpro:IPR036389|interpro:IPR038248|interpro:IPR044441|reactome:R-DME-203927|reactome:R-DME-426486 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2017/08/04 2017/08/10 rogid:b4hUTrpZAKdYrKrNXyii52Zz43Y7227 rogid:qQiK00k/1UZST/JWnD/HUdltS9w7227 rigid:DKU5emuACycx/C4Gj4aiayOiBu8 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9VJY9 uniprotkb:Q9VCU9 intact:EBI-638074|ensemblmetazoa:FBpp0080076|uniprotkb:Q8SZ74 intact:EBI-112170|uniprotkb:Q961S7|ensemblmetazoa:FBpp0083717 psi-mi:q9vjy9_drome(display_long)|uniprotkb:loqs(gene name)|psi-mi:loqs(display_short)|uniprotkb:Loqs-PD(gene name synonym)|uniprotkb:LqPD(gene name synonym)|uniprotkb:Dmel\CG6866(gene name synonym)|uniprotkb:LOQS(gene name synonym)|uniprotkb:Loqs(gene name synonym)|uniprotkb:R3D1(gene name synonym)|uniprotkb:R3D1-L(gene name synonym)|uniprotkb:R3D1-S(gene name synonym)|uniprotkb:TRBP(gene name synonym)|uniprotkb:dRax(gene name synonym)|uniprotkb:loq(gene name synonym)|uniprotkb:r3d1(gene name synonym)|uniprotkb:Dmel_CG6866(orf name)|uniprotkb:cg6866(gene name synonym)|uniprotkb:CG6866(orf name) psi-mi:dcr1_drome(display_long)|uniprotkb:Dcr-1(gene name)|psi-mi:Dcr-1(display_short)|uniprotkb:CG4792(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Förstemann et al. (2005) pubmed:15918770|doi:10.1371/journal.pbio.0030236|imex:IM-9330 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15552751|imex:IM-9330-7|dip:DIP-87846E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0032515(gene)|ensemblmetazoa:FBtr0080498(transcript)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007417"(central nervous system development)|go:"GO:0009047"(dosage compensation by hyperactivation of X chromosome)|go:"GO:0010586"(miRNA metabolic process)|go:"GO:0030422"(production of siRNA involved in RNA interference)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0035087"(siRNA loading onto RISC involved in RNA interference)|go:"GO:0035197"(siRNA binding)|go:"GO:0048132"(female germ-line stem cell asymmetric division)|refseq:NP_609646.1|flybase:FBgn0032515|go:"GO:0070578"(RISC-loading complex)|go:"GO:0070877"(microprocessor complex)|go:"GO:0070918"(primary sncRNA processing)|go:"GO:0070920"(regulation of production of small RNA involved in gene silencing by RNA)|go:"GO:1905172"(RISC complex binding)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR032478|rcsb pdb:4X8W|reactome:R-DME-203927|reactome:R-DME-426486|dip:DIP-18138N refseq:NP_524453.1|flybase:FBgn0039016|dip:DIP-23028N|ensemblmetazoa:FBgn0039016(gene)|ensemblmetazoa:FBtr0084324(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0004525"(ribonuclease III activity)|go:"GO:0004530"(deoxyribonuclease I activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006309"(apoptotic DNA fragmentation)|go:"GO:0007279"(pole cell formation)|go:"GO:0007294"(germarium-derived oocyte fate determination)|go:"GO:0007367"(segment polarity determination)|go:"GO:0016246"(RNA interference)|go:"GO:0016442"(RISC complex)|go:"GO:0016443"(bidentate ribonuclease III activity)|go:"GO:0030422"(production of siRNA involved in RNA interference)|go:"GO:0030727"(germarium-derived female germ-line cyst formation)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0033227"(dsRNA transport)|go:"GO:0035087"(siRNA loading onto RISC involved in RNA interference)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0042078"(germ-line stem cell division)|go:"GO:0042594"(response to starvation)|go:"GO:0045448"(mitotic cell cycle, embryonic)|go:"GO:0046872"(metal ion binding)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0070578"(RISC-loading complex)|go:"GO:0070883"(pre-miRNA binding)|go:"GO:0090501"(RNA phosphodiester bond hydrolysis)|interpro:IPR000999(Ribonuclease III)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR003100(Argonaute and Dicer protein, PAZ)|interpro:IPR005034(Protein of unknown function DUF283)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR027417|interpro:IPR036085|interpro:IPR036389|interpro:IPR038248|interpro:IPR044441|reactome:R-DME-203927|reactome:R-DME-426486 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2017/08/04 2017/08/10 rogid:b4hUTrpZAKdYrKrNXyii52Zz43Y7227 rogid:qQiK00k/1UZST/JWnD/HUdltS9w7227 rigid:DKU5emuACycx/C4Gj4aiayOiBu8 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9VCU9 uniprotkb:Q8IP72 intact:EBI-112170|uniprotkb:Q961S7|ensemblmetazoa:FBpp0083717 intact:EBI-162836|ensemblmetazoa:FBpp0080075 psi-mi:dcr1_drome(display_long)|uniprotkb:Dcr-1(gene name)|psi-mi:Dcr-1(display_short)|uniprotkb:CG4792(orf name) psi-mi:q8ip72_drome(display_long)|uniprotkb:loqs(gene name)|psi-mi:loqs(display_short)|uniprotkb:Dmel\CG6866(gene name synonym)|uniprotkb:LOQS(gene name synonym)|uniprotkb:Loqs(gene name synonym)|uniprotkb:R3D1(gene name synonym)|uniprotkb:R3D1-L(gene name synonym)|uniprotkb:R3D1-S(gene name synonym)|uniprotkb:TRBP(gene name synonym)|uniprotkb:dRax(gene name synonym)|uniprotkb:loq(gene name synonym)|uniprotkb:r3d1(gene name synonym)|uniprotkb:Dmel_CG6866(orf name)|uniprotkb:CG6866(orf name)|uniprotkb:cg6866(gene name synonym)|uniprotkb:Loqs-PD(gene name synonym)|uniprotkb:LqPD(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Förstemann et al. (2005) pubmed:15918770|doi:10.1371/journal.pbio.0030236|imex:IM-9330 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15552768|imex:IM-9330-3|dip:DIP-87845E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524453.1|flybase:FBgn0039016|dip:DIP-23028N|ensemblmetazoa:FBgn0039016(gene)|ensemblmetazoa:FBtr0084324(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0004525"(ribonuclease III activity)|go:"GO:0004530"(deoxyribonuclease I activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006309"(apoptotic DNA fragmentation)|go:"GO:0007279"(pole cell formation)|go:"GO:0007294"(germarium-derived oocyte fate determination)|go:"GO:0007367"(segment polarity determination)|go:"GO:0016246"(RNA interference)|go:"GO:0016442"(RISC complex)|go:"GO:0016443"(bidentate ribonuclease III activity)|go:"GO:0030422"(production of siRNA involved in RNA interference)|go:"GO:0030727"(germarium-derived female germ-line cyst formation)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0033227"(dsRNA transport)|go:"GO:0035087"(siRNA loading onto RISC involved in RNA interference)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0042078"(germ-line stem cell division)|go:"GO:0042594"(response to starvation)|go:"GO:0045448"(mitotic cell cycle, embryonic)|go:"GO:0046872"(metal ion binding)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0070578"(RISC-loading complex)|go:"GO:0070883"(pre-miRNA binding)|go:"GO:0090501"(RNA phosphodiester bond hydrolysis)|interpro:IPR000999(Ribonuclease III)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR003100(Argonaute and Dicer protein, PAZ)|interpro:IPR005034(Protein of unknown function DUF283)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR027417|interpro:IPR036085|interpro:IPR036389|interpro:IPR038248|interpro:IPR044441|reactome:R-DME-203927|reactome:R-DME-426486 refseq:NP_723813.1|flybase:FBgn0032515|ensemblmetazoa:FBgn0032515(gene)|ensemblmetazoa:FBtr0080497(transcript)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007417"(central nervous system development)|go:"GO:0009047"(dosage compensation by hyperactivation of X chromosome)|go:"GO:0010586"(miRNA metabolic process)|go:"GO:0030422"(production of siRNA involved in RNA interference)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0048132"(female germ-line stem cell asymmetric division)|go:"GO:0070918"(primary sncRNA processing)|go:"GO:0070920"(regulation of production of small RNA involved in gene silencing by RNA)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR032478|dip:DIP-46082N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2017/08/04 2017/08/10 rogid:qQiK00k/1UZST/JWnD/HUdltS9w7227 rogid:sK/JdnkQDPAuc6wJ1a0qlMg+LLQ7227 rigid:40zh7h7xBAvCBbKYJ7dRbVmUoeU false - myc tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9VCU9 uniprotkb:Q8IP72 intact:EBI-112170|uniprotkb:Q961S7|ensemblmetazoa:FBpp0083717 intact:EBI-162836|ensemblmetazoa:FBpp0080075 psi-mi:dcr1_drome(display_long)|uniprotkb:Dcr-1(gene name)|psi-mi:Dcr-1(display_short)|uniprotkb:CG4792(orf name) psi-mi:q8ip72_drome(display_long)|uniprotkb:loqs(gene name)|psi-mi:loqs(display_short)|uniprotkb:Dmel\CG6866(gene name synonym)|uniprotkb:LOQS(gene name synonym)|uniprotkb:Loqs(gene name synonym)|uniprotkb:R3D1(gene name synonym)|uniprotkb:R3D1-L(gene name synonym)|uniprotkb:R3D1-S(gene name synonym)|uniprotkb:TRBP(gene name synonym)|uniprotkb:dRax(gene name synonym)|uniprotkb:loq(gene name synonym)|uniprotkb:r3d1(gene name synonym)|uniprotkb:Dmel_CG6866(orf name)|uniprotkb:CG6866(orf name)|uniprotkb:cg6866(gene name synonym)|uniprotkb:Loqs-PD(gene name synonym)|uniprotkb:LqPD(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Förstemann et al. (2005) pubmed:15918770|doi:10.1371/journal.pbio.0030236|imex:IM-9330 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15552715|imex:IM-9330-6|dip:DIP-87845E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524453.1|flybase:FBgn0039016|dip:DIP-23028N|ensemblmetazoa:FBgn0039016(gene)|ensemblmetazoa:FBtr0084324(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0004525"(ribonuclease III activity)|go:"GO:0004530"(deoxyribonuclease I activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006309"(apoptotic DNA fragmentation)|go:"GO:0007279"(pole cell formation)|go:"GO:0007294"(germarium-derived oocyte fate determination)|go:"GO:0007367"(segment polarity determination)|go:"GO:0016246"(RNA interference)|go:"GO:0016442"(RISC complex)|go:"GO:0016443"(bidentate ribonuclease III activity)|go:"GO:0030422"(production of siRNA involved in RNA interference)|go:"GO:0030727"(germarium-derived female germ-line cyst formation)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0033227"(dsRNA transport)|go:"GO:0035087"(siRNA loading onto RISC involved in RNA interference)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0042078"(germ-line stem cell division)|go:"GO:0042594"(response to starvation)|go:"GO:0045448"(mitotic cell cycle, embryonic)|go:"GO:0046872"(metal ion binding)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0070578"(RISC-loading complex)|go:"GO:0070883"(pre-miRNA binding)|go:"GO:0090501"(RNA phosphodiester bond hydrolysis)|interpro:IPR000999(Ribonuclease III)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR003100(Argonaute and Dicer protein, PAZ)|interpro:IPR005034(Protein of unknown function DUF283)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR027417|interpro:IPR036085|interpro:IPR036389|interpro:IPR038248|interpro:IPR044441|reactome:R-DME-203927|reactome:R-DME-426486 refseq:NP_723813.1|flybase:FBgn0032515|ensemblmetazoa:FBgn0032515(gene)|ensemblmetazoa:FBtr0080497(transcript)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007417"(central nervous system development)|go:"GO:0009047"(dosage compensation by hyperactivation of X chromosome)|go:"GO:0010586"(miRNA metabolic process)|go:"GO:0030422"(production of siRNA involved in RNA interference)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0048132"(female germ-line stem cell asymmetric division)|go:"GO:0070918"(primary sncRNA processing)|go:"GO:0070920"(regulation of production of small RNA involved in gene silencing by RNA)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR032478|dip:DIP-46082N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2017/08/04 2017/08/10 rogid:qQiK00k/1UZST/JWnD/HUdltS9w7227 rogid:sK/JdnkQDPAuc6wJ1a0qlMg+LLQ7227 rigid:40zh7h7xBAvCBbKYJ7dRbVmUoeU false - myc tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9VCU9 uniprotkb:Q8IP72 intact:EBI-112170|uniprotkb:Q961S7|ensemblmetazoa:FBpp0083717 intact:EBI-162836|ensemblmetazoa:FBpp0080075 psi-mi:dcr1_drome(display_long)|uniprotkb:Dcr-1(gene name)|psi-mi:Dcr-1(display_short)|uniprotkb:CG4792(orf name) psi-mi:q8ip72_drome(display_long)|uniprotkb:loqs(gene name)|psi-mi:loqs(display_short)|uniprotkb:Dmel\CG6866(gene name synonym)|uniprotkb:LOQS(gene name synonym)|uniprotkb:Loqs(gene name synonym)|uniprotkb:R3D1(gene name synonym)|uniprotkb:R3D1-L(gene name synonym)|uniprotkb:R3D1-S(gene name synonym)|uniprotkb:TRBP(gene name synonym)|uniprotkb:dRax(gene name synonym)|uniprotkb:loq(gene name synonym)|uniprotkb:r3d1(gene name synonym)|uniprotkb:Dmel_CG6866(orf name)|uniprotkb:CG6866(orf name)|uniprotkb:cg6866(gene name synonym)|uniprotkb:Loqs-PD(gene name synonym)|uniprotkb:LqPD(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Förstemann et al. (2005) pubmed:15918770|doi:10.1371/journal.pbio.0030236|imex:IM-9330 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15552697|imex:IM-9330-5|dip:DIP-87844E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524453.1|flybase:FBgn0039016|dip:DIP-23028N|ensemblmetazoa:FBgn0039016(gene)|ensemblmetazoa:FBtr0084324(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0004525"(ribonuclease III activity)|go:"GO:0004530"(deoxyribonuclease I activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006309"(apoptotic DNA fragmentation)|go:"GO:0007279"(pole cell formation)|go:"GO:0007294"(germarium-derived oocyte fate determination)|go:"GO:0007367"(segment polarity determination)|go:"GO:0016246"(RNA interference)|go:"GO:0016442"(RISC complex)|go:"GO:0016443"(bidentate ribonuclease III activity)|go:"GO:0030422"(production of siRNA involved in RNA interference)|go:"GO:0030727"(germarium-derived female germ-line cyst formation)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0033227"(dsRNA transport)|go:"GO:0035087"(siRNA loading onto RISC involved in RNA interference)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0042078"(germ-line stem cell division)|go:"GO:0042594"(response to starvation)|go:"GO:0045448"(mitotic cell cycle, embryonic)|go:"GO:0046872"(metal ion binding)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0070578"(RISC-loading complex)|go:"GO:0070883"(pre-miRNA binding)|go:"GO:0090501"(RNA phosphodiester bond hydrolysis)|interpro:IPR000999(Ribonuclease III)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR003100(Argonaute and Dicer protein, PAZ)|interpro:IPR005034(Protein of unknown function DUF283)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR027417|interpro:IPR036085|interpro:IPR036389|interpro:IPR038248|interpro:IPR044441|reactome:R-DME-203927|reactome:R-DME-426486 refseq:NP_723813.1|flybase:FBgn0032515|ensemblmetazoa:FBgn0032515(gene)|ensemblmetazoa:FBtr0080497(transcript)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007417"(central nervous system development)|go:"GO:0009047"(dosage compensation by hyperactivation of X chromosome)|go:"GO:0010586"(miRNA metabolic process)|go:"GO:0030422"(production of siRNA involved in RNA interference)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0048132"(female germ-line stem cell asymmetric division)|go:"GO:0070918"(primary sncRNA processing)|go:"GO:0070920"(regulation of production of small RNA involved in gene silencing by RNA)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR032478|dip:DIP-46082N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2017/08/04 2017/08/10 rogid:qQiK00k/1UZST/JWnD/HUdltS9w7227 rogid:sK/JdnkQDPAuc6wJ1a0qlMg+LLQ7227 rigid:qWs2vyCMbzgK9Gz7wX7iza0sKRM false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9VCU9 uniprotkb:Q9VJY9 intact:EBI-112170|uniprotkb:Q961S7|ensemblmetazoa:FBpp0083717 intact:EBI-638074|ensemblmetazoa:FBpp0080076|uniprotkb:Q8SZ74 psi-mi:dcr1_drome(display_long)|uniprotkb:Dcr-1(gene name)|psi-mi:Dcr-1(display_short)|uniprotkb:CG4792(orf name) psi-mi:q9vjy9_drome(display_long)|uniprotkb:loqs(gene name)|psi-mi:loqs(display_short)|uniprotkb:Loqs-PD(gene name synonym)|uniprotkb:LqPD(gene name synonym)|uniprotkb:Dmel\CG6866(gene name synonym)|uniprotkb:LOQS(gene name synonym)|uniprotkb:Loqs(gene name synonym)|uniprotkb:R3D1(gene name synonym)|uniprotkb:R3D1-L(gene name synonym)|uniprotkb:R3D1-S(gene name synonym)|uniprotkb:TRBP(gene name synonym)|uniprotkb:dRax(gene name synonym)|uniprotkb:loq(gene name synonym)|uniprotkb:r3d1(gene name synonym)|uniprotkb:Dmel_CG6866(orf name)|uniprotkb:cg6866(gene name synonym)|uniprotkb:CG6866(orf name) psi-mi:"MI:0071"(molecular sieving) Förstemann et al. (2005) pubmed:15918770|doi:10.1371/journal.pbio.0030236|imex:IM-9330 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15552697|imex:IM-9330-5|dip:DIP-87844E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524453.1|flybase:FBgn0039016|dip:DIP-23028N|ensemblmetazoa:FBgn0039016(gene)|ensemblmetazoa:FBtr0084324(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0004525"(ribonuclease III activity)|go:"GO:0004530"(deoxyribonuclease I activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006309"(apoptotic DNA fragmentation)|go:"GO:0007279"(pole cell formation)|go:"GO:0007294"(germarium-derived oocyte fate determination)|go:"GO:0007367"(segment polarity determination)|go:"GO:0016246"(RNA interference)|go:"GO:0016442"(RISC complex)|go:"GO:0016443"(bidentate ribonuclease III activity)|go:"GO:0030422"(production of siRNA involved in RNA interference)|go:"GO:0030727"(germarium-derived female germ-line cyst formation)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0033227"(dsRNA transport)|go:"GO:0035087"(siRNA loading onto RISC involved in RNA interference)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0042078"(germ-line stem cell division)|go:"GO:0042594"(response to starvation)|go:"GO:0045448"(mitotic cell cycle, embryonic)|go:"GO:0046872"(metal ion binding)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0070578"(RISC-loading complex)|go:"GO:0070883"(pre-miRNA binding)|go:"GO:0090501"(RNA phosphodiester bond hydrolysis)|interpro:IPR000999(Ribonuclease III)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR003100(Argonaute and Dicer protein, PAZ)|interpro:IPR005034(Protein of unknown function DUF283)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR027417|interpro:IPR036085|interpro:IPR036389|interpro:IPR038248|interpro:IPR044441|reactome:R-DME-203927|reactome:R-DME-426486 ensemblmetazoa:FBgn0032515(gene)|ensemblmetazoa:FBtr0080498(transcript)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007417"(central nervous system development)|go:"GO:0009047"(dosage compensation by hyperactivation of X chromosome)|go:"GO:0010586"(miRNA metabolic process)|go:"GO:0030422"(production of siRNA involved in RNA interference)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0035087"(siRNA loading onto RISC involved in RNA interference)|go:"GO:0035197"(siRNA binding)|go:"GO:0048132"(female germ-line stem cell asymmetric division)|refseq:NP_609646.1|flybase:FBgn0032515|go:"GO:0070578"(RISC-loading complex)|go:"GO:0070877"(microprocessor complex)|go:"GO:0070918"(primary sncRNA processing)|go:"GO:0070920"(regulation of production of small RNA involved in gene silencing by RNA)|go:"GO:1905172"(RISC complex binding)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR032478|rcsb pdb:4X8W|reactome:R-DME-203927|reactome:R-DME-426486|dip:DIP-18138N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2017/08/04 2017/08/10 rogid:qQiK00k/1UZST/JWnD/HUdltS9w7227 rogid:b4hUTrpZAKdYrKrNXyii52Zz43Y7227 rigid:qWs2vyCMbzgK9Gz7wX7iza0sKRM false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9VJY9 uniprotkb:Q9VCU9 intact:EBI-638074|ensemblmetazoa:FBpp0080076|uniprotkb:Q8SZ74 intact:EBI-112170|uniprotkb:Q961S7|ensemblmetazoa:FBpp0083717 psi-mi:q9vjy9_drome(display_long)|uniprotkb:loqs(gene name)|psi-mi:loqs(display_short)|uniprotkb:Loqs-PD(gene name synonym)|uniprotkb:LqPD(gene name synonym)|uniprotkb:Dmel\CG6866(gene name synonym)|uniprotkb:LOQS(gene name synonym)|uniprotkb:Loqs(gene name synonym)|uniprotkb:R3D1(gene name synonym)|uniprotkb:R3D1-L(gene name synonym)|uniprotkb:R3D1-S(gene name synonym)|uniprotkb:TRBP(gene name synonym)|uniprotkb:dRax(gene name synonym)|uniprotkb:loq(gene name synonym)|uniprotkb:r3d1(gene name synonym)|uniprotkb:Dmel_CG6866(orf name)|uniprotkb:cg6866(gene name synonym)|uniprotkb:CG6866(orf name) psi-mi:dcr1_drome(display_long)|uniprotkb:Dcr-1(gene name)|psi-mi:Dcr-1(display_short)|uniprotkb:CG4792(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Förstemann et al. (2005) pubmed:15918770|doi:10.1371/journal.pbio.0030236|imex:IM-9330 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15552787|imex:IM-9330-8|dip:DIP-87846E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0032515(gene)|ensemblmetazoa:FBtr0080498(transcript)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007417"(central nervous system development)|go:"GO:0009047"(dosage compensation by hyperactivation of X chromosome)|go:"GO:0010586"(miRNA metabolic process)|go:"GO:0030422"(production of siRNA involved in RNA interference)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0035087"(siRNA loading onto RISC involved in RNA interference)|go:"GO:0035197"(siRNA binding)|go:"GO:0048132"(female germ-line stem cell asymmetric division)|refseq:NP_609646.1|flybase:FBgn0032515|go:"GO:0070578"(RISC-loading complex)|go:"GO:0070877"(microprocessor complex)|go:"GO:0070918"(primary sncRNA processing)|go:"GO:0070920"(regulation of production of small RNA involved in gene silencing by RNA)|go:"GO:1905172"(RISC complex binding)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR032478|rcsb pdb:4X8W|reactome:R-DME-203927|reactome:R-DME-426486|dip:DIP-18138N refseq:NP_524453.1|flybase:FBgn0039016|dip:DIP-23028N|ensemblmetazoa:FBgn0039016(gene)|ensemblmetazoa:FBtr0084324(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0004525"(ribonuclease III activity)|go:"GO:0004530"(deoxyribonuclease I activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006309"(apoptotic DNA fragmentation)|go:"GO:0007279"(pole cell formation)|go:"GO:0007294"(germarium-derived oocyte fate determination)|go:"GO:0007367"(segment polarity determination)|go:"GO:0016246"(RNA interference)|go:"GO:0016442"(RISC complex)|go:"GO:0016443"(bidentate ribonuclease III activity)|go:"GO:0030422"(production of siRNA involved in RNA interference)|go:"GO:0030727"(germarium-derived female germ-line cyst formation)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0033227"(dsRNA transport)|go:"GO:0035087"(siRNA loading onto RISC involved in RNA interference)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0042078"(germ-line stem cell division)|go:"GO:0042594"(response to starvation)|go:"GO:0045448"(mitotic cell cycle, embryonic)|go:"GO:0046872"(metal ion binding)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0070578"(RISC-loading complex)|go:"GO:0070883"(pre-miRNA binding)|go:"GO:0090501"(RNA phosphodiester bond hydrolysis)|interpro:IPR000999(Ribonuclease III)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR003100(Argonaute and Dicer protein, PAZ)|interpro:IPR005034(Protein of unknown function DUF283)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR027417|interpro:IPR036085|interpro:IPR036389|interpro:IPR038248|interpro:IPR044441|reactome:R-DME-203927|reactome:R-DME-426486 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2017/08/04 2017/08/10 rogid:b4hUTrpZAKdYrKrNXyii52Zz43Y7227 rogid:qQiK00k/1UZST/JWnD/HUdltS9w7227 rigid:DKU5emuACycx/C4Gj4aiayOiBu8 false myc tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)