#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B intact:EBI-15552169 uniprotkb:P35961 dip:DIP-48440N intact:EBI-15259527 psi-mi:cd4m33/f23(display_short)|psi-mi:EBI-15552169(display_long) psi-mi:env_hv1y2(display_long)|uniprotkb:env(gene name)|psi-mi:env(display_short)|uniprotkb:Env polyprotein(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Huang et al. (2005) pubmed:15893666|doi:10.1016/j.str.2005.03.006|imex:IM-14194 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:362651(hv1y2)|taxid:362651("Human immunodeficiency virus type 1 group M subtype B (isolate YU-2) (HIV-1)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15552172|imex:IM-14194-1|dip:DIP-102907E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0327"(peptide) psi-mi:"MI:0326"(protein) - go:"GO:0005198"(structural molecule activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019064"(fusion of virus membrane with host plasma membrane)|go:"GO:0019082"(viral protein processing)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0044175"(host cell endosome membrane)|go:"GO:0044423"(virion component)|go:"GO:0055036"(virion membrane)|go:"GO:0075512"(clathrin-dependent endocytosis of virus by host cell)|go:"GO:0090527"(actin filament reorganization)|go:"GO:1903905"(positive regulation of establishment of T cell polarity)|rcsb pdb:5A8H|rcsb pdb:5A7X|rcsb pdb:1G9N|rcsb pdb:1RZK|go:"GO:1903908"(positive regulation of plasma membrane raft polarization)|go:"GO:1903911"(positive regulation of receptor clustering)|rcsb pdb:1YYL|rcsb pdb:1YYM|interpro:IPR000328(Envelope Polyprotein GP41)|rcsb pdb:2I5Y|interpro:IPR000777(Envelope glycoprotein GP120)|interpro:IPR036377|interpro:IPR037527|rcsb pdb:2I60|rcsb pdb:2NY7|rcsb pdb:2QAD|rcsb pdb:3HI1|rcsb pdb:3TGQ|rcsb pdb:4DVR|rcsb pdb:4JO3|rcsb pdb:4JZW|rcsb pdb:4JZZ|rcsb pdb:4K0A|rcsb pdb:4KA2|rcsb pdb:4LAJ|rcsb pdb:4R4F|rcsb pdb:4RQS|rcsb pdb:4RWY|reactome:R-HSA-5621480|dip:DIP-48439N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/04 2017/08/10 rogid:HV9jV1LKmrzVoFU+MMglT8nvMd8-2 rogid:NEvHMSYvQtC6tHfdZ/NqCejVI+E362651 rigid:abGqikCYtlMNH88Hlkc2Ib1RB3s false - polyprotein fragment:82-479 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) intact:EBI-15552169 uniprotkb:P35961 dip:DIP-48440N intact:EBI-15259527 psi-mi:cd4m33/f23(display_short)|psi-mi:EBI-15552169(display_long) psi-mi:env_hv1y2(display_long)|uniprotkb:env(gene name)|psi-mi:env(display_short)|uniprotkb:Env polyprotein(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Huang et al. (2005) pubmed:15893666|doi:10.1016/j.str.2005.03.006|imex:IM-14194 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:362651(hv1y2)|taxid:362651("Human immunodeficiency virus type 1 group M subtype B (isolate YU-2) (HIV-1)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15552191|imex:IM-14194-2|dip:DIP-102907E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0327"(peptide) psi-mi:"MI:0326"(protein) - go:"GO:0005198"(structural molecule activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019064"(fusion of virus membrane with host plasma membrane)|go:"GO:0019082"(viral protein processing)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0044175"(host cell endosome membrane)|go:"GO:0044423"(virion component)|go:"GO:0055036"(virion membrane)|go:"GO:0075512"(clathrin-dependent endocytosis of virus by host cell)|go:"GO:0090527"(actin filament reorganization)|go:"GO:1903905"(positive regulation of establishment of T cell polarity)|rcsb pdb:5A8H|rcsb pdb:5A7X|rcsb pdb:1G9N|rcsb pdb:1RZK|go:"GO:1903908"(positive regulation of plasma membrane raft polarization)|go:"GO:1903911"(positive regulation of receptor clustering)|rcsb pdb:1YYL|rcsb pdb:1YYM|interpro:IPR000328(Envelope Polyprotein GP41)|rcsb pdb:2I5Y|interpro:IPR000777(Envelope glycoprotein GP120)|interpro:IPR036377|interpro:IPR037527|rcsb pdb:2I60|rcsb pdb:2NY7|rcsb pdb:2QAD|rcsb pdb:3HI1|rcsb pdb:3TGQ|rcsb pdb:4DVR|rcsb pdb:4JO3|rcsb pdb:4JZW|rcsb pdb:4JZZ|rcsb pdb:4K0A|rcsb pdb:4KA2|rcsb pdb:4LAJ|rcsb pdb:4R4F|rcsb pdb:4RQS|rcsb pdb:4RWY|reactome:R-HSA-5621480|dip:DIP-48439N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/04 2017/08/10 rogid:HV9jV1LKmrzVoFU+MMglT8nvMd8-2 rogid:NEvHMSYvQtC6tHfdZ/NqCejVI+E362651 rigid:abGqikCYtlMNH88Hlkc2Ib1RB3s false - polyprotein fragment:82-479 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)