#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9UQE7	uniprotkb:Q8N3U4	intact:EBI-80718|ensembl:ENSP00000354720|uniprotkb:O60464|uniprotkb:Q5T482|uniprotkb:A8K156	intact:EBI-1057252|uniprotkb:O00540|uniprotkb:Q5JTI6|uniprotkb:Q9H1N8|uniprotkb:D3DTF5|intact:EBI-2559208|uniprotkb:B1AMT5|uniprotkb:Q68DE9|ensembl:ENSP00000360186|ensembl:ENSP00000360199|ensembl:ENSP00000360202	psi-mi:smc3_human(display_long)|uniprotkb:SMC3(gene name)|psi-mi:SMC3(display_short)|uniprotkb:BAM(gene name synonym)|uniprotkb:SMC3L1(gene name synonym)|uniprotkb:Chondroitin sulfate proteoglycan 6(gene name synonym)|uniprotkb:Chromosome-associated polypeptide(gene name synonym)|uniprotkb:Basement membrane-associated chondroitin proteoglycan(gene name synonym)|uniprotkb:BMH(gene name synonym)|uniprotkb:CSPG6(gene name synonym)	psi-mi:stag2_human(display_long)|uniprotkb:STAG2(gene name)|psi-mi:STAG2(display_short)|uniprotkb:SA2(gene name synonym)|uniprotkb:Stromal antigen 2(gene name synonym)|uniprotkb:SCC3 homolog 2(gene name synonym)	psi-mi:"MI:0029"(cosedimentation through density gradient)	Hauf et al. (2005)	pubmed:15737063|doi:10.1371/journal.pbio.0030069|imex:IM-9328	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15551562|imex:IM-9328-1|dip:DIP-67090E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR036277|interpro:IPR041741|mint:Q9UQE7|rcsb pdb:6WG3|rcsb pdb:6WG4|rcsb pdb:6WG6|rcsb pdb:6WGE|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|go:"GO:0070840"(dynein complex binding)|ensembl:ENSG00000108055(gene)|ensembl:ENST00000361804(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000800"(lateral element)|go:"GO:0003682"(chromatin binding)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030893"(meiotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0036033"(mediator complex binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|refseq:NP_005436.1|dip:DIP-29200N	refseq:NP_001036214.1|refseq:NP_001036215.1|refseq:NP_001036216.1|refseq:XP_011529555.1|refseq:NP_006594.3|refseq:NP_001269347.1|refseq:XP_005262414.1|refseq:XP_005262415.1|refseq:XP_005262416.1|refseq:XP_005262417.1|refseq:XP_005262418.1|refseq:XP_006724790.1|ensembl:ENSG00000101972(gene)|ensembl:ENST00000371144(transcript)|ensembl:ENST00000371157(transcript)|ensembl:ENST00000371160(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR013721(STAG)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR020839|interpro:IPR039662|mint:Q8N3U4|rcsb pdb:4PJU|rcsb pdb:4PJW|rcsb pdb:4PK7|rcsb pdb:6QNX|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|go:"GO:0005829"(cytosol)|refseq:XP_016884721.1|refseq:XP_016884722.1|refseq:XP_016884723.1|dip:DIP-35418N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/04	2017/08/10	rogid:pUxr+sTtttRzGlqCRz/25woNtrg9606	rogid:sJ813DVkungq+1f1rgugDN2gsn09606	rigid:w/sZEFE8cn/txVq+PzOizMOJHYE	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9UQE7	uniprotkb:Q8N3U4	intact:EBI-80718|ensembl:ENSP00000354720|uniprotkb:O60464|uniprotkb:Q5T482|uniprotkb:A8K156	intact:EBI-1057252|uniprotkb:O00540|uniprotkb:Q5JTI6|uniprotkb:Q9H1N8|uniprotkb:D3DTF5|intact:EBI-2559208|uniprotkb:B1AMT5|uniprotkb:Q68DE9|ensembl:ENSP00000360186|ensembl:ENSP00000360199|ensembl:ENSP00000360202	psi-mi:smc3_human(display_long)|uniprotkb:SMC3(gene name)|psi-mi:SMC3(display_short)|uniprotkb:BAM(gene name synonym)|uniprotkb:SMC3L1(gene name synonym)|uniprotkb:Chondroitin sulfate proteoglycan 6(gene name synonym)|uniprotkb:Chromosome-associated polypeptide(gene name synonym)|uniprotkb:Basement membrane-associated chondroitin proteoglycan(gene name synonym)|uniprotkb:BMH(gene name synonym)|uniprotkb:CSPG6(gene name synonym)	psi-mi:stag2_human(display_long)|uniprotkb:STAG2(gene name)|psi-mi:STAG2(display_short)|uniprotkb:SA2(gene name synonym)|uniprotkb:Stromal antigen 2(gene name synonym)|uniprotkb:SCC3 homolog 2(gene name synonym)	psi-mi:"MI:0029"(cosedimentation through density gradient)	Hauf et al. (2005)	pubmed:15737063|doi:10.1371/journal.pbio.0030069|imex:IM-9328	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15551562|imex:IM-9328-1|dip:DIP-67090E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR036277|interpro:IPR041741|mint:Q9UQE7|rcsb pdb:6WG3|rcsb pdb:6WG4|rcsb pdb:6WG6|rcsb pdb:6WGE|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|go:"GO:0070840"(dynein complex binding)|ensembl:ENSG00000108055(gene)|ensembl:ENST00000361804(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000800"(lateral element)|go:"GO:0003682"(chromatin binding)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030893"(meiotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0036033"(mediator complex binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|refseq:NP_005436.1|dip:DIP-29200N	refseq:NP_001036214.1|refseq:NP_001036215.1|refseq:NP_001036216.1|refseq:XP_011529555.1|refseq:NP_006594.3|refseq:NP_001269347.1|refseq:XP_005262414.1|refseq:XP_005262415.1|refseq:XP_005262416.1|refseq:XP_005262417.1|refseq:XP_005262418.1|refseq:XP_006724790.1|ensembl:ENSG00000101972(gene)|ensembl:ENST00000371144(transcript)|ensembl:ENST00000371157(transcript)|ensembl:ENST00000371160(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR013721(STAG)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR020839|interpro:IPR039662|mint:Q8N3U4|rcsb pdb:4PJU|rcsb pdb:4PJW|rcsb pdb:4PK7|rcsb pdb:6QNX|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|go:"GO:0005829"(cytosol)|refseq:XP_016884721.1|refseq:XP_016884722.1|refseq:XP_016884723.1|dip:DIP-35418N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/04	2017/08/10	rogid:pUxr+sTtttRzGlqCRz/25woNtrg9606	rogid:sJ813DVkungq+1f1rgugDN2gsn09606	rigid:w/sZEFE8cn/txVq+PzOizMOJHYE	false	-	myc tag:c-c	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O60216	uniprotkb:Q14674	intact:EBI-80739|ensembl:ENSP00000297338|uniprotkb:Q15001|uniprotkb:Q99568|uniprotkb:A8K0E0	intact:EBI-2554882|intact:EBI-28978215|ensembl:ENSP00000257934	psi-mi:rad21_human(display_long)|uniprotkb:RAD21(gene name)|psi-mi:RAD21(display_short)|uniprotkb:HR21(gene name synonym)|uniprotkb:KIAA0078(gene name synonym)|uniprotkb:Nuclear matrix protein 1(gene name synonym)|uniprotkb:SCC1 homolog(gene name synonym)|uniprotkb:NXP1(gene name synonym)|uniprotkb:SCC1(gene name synonym)	psi-mi:espl1_human(display_long)|uniprotkb:ESP1(gene name synonym)|uniprotkb:KIAA0165(gene name synonym)|uniprotkb:Separase(gene name synonym)|uniprotkb:Caspase-like protein ESPL1(gene name synonym)|uniprotkb:Extra spindle poles-like 1 protein(gene name synonym)|uniprotkb:ESPL1(gene name)|psi-mi:ESPL1(display_short)	psi-mi:"MI:0435"(protease assay)	Hauf et al. (2005)	pubmed:15737063|doi:10.1371/journal.pbio.0030069|imex:IM-9328	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15551582|imex:IM-9328-2|dip:DIP-87842E	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000164754(gene)|ensembl:ENST00000297338(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000922"(spindle pole)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0008278"(cohesin complex)|go:"GO:0010972"(negative regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0045841"(negative regulation of mitotic metaphase/anaphase transition)|go:"GO:0045876"(positive regulation of sister chromatid cohesion)|go:"GO:0051301"(cell division)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR006909(Rad21/Rec8 like protein, C-terminal)|interpro:IPR006910(Rad21/Rec8 like protein, N-terminal)|interpro:IPR023093|interpro:IPR036390|interpro:IPR039781|mint:O60216|rcsb pdb:4PJU|rcsb pdb:6WGE|reactome:R-HSA-1221632|reactome:R-HSA-2467813|rcsb pdb:4PJW|rcsb pdb:4PK7|rcsb pdb:6QNX|rcsb pdb:6RRC|reactome:R-HSA-2468052|rcsb pdb:6RRK|reactome:R-HSA-2470946|rcsb pdb:6WG3|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|refseq:NP_006256.1|dip:DIP-29201N	refseq:NP_036423.4|refseq:XP_011537326.1|ensembl:ENSP00000257934|refseq:XP_006719768.1|refseq:XP_016875742.1|dip:DIP-46079N|ensembl:ENST00000257934(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000212"(meiotic spindle organization)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0003824"(catalytic activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0045875"(negative regulation of sister chromatid cohesion)|go:"GO:0051307"(meiotic chromosome separation)|go:"GO:0072686"(mitotic spindle)|interpro:IPR005314(Peptidase C50, separase)|interpro:IPR030397|reactome:R-HSA-2467813|ensembl:ENSG00000135476(gene)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/04	2017/08/10	rogid:9H+Fipb91zQo7ie3YHCL7Ardveo9606	rogid:oK4Wg46DenILU6xADFkxkybkOcI9606	rigid:XPYrg1Oew1AV0vpqGPjTq/etqgc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)