#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P25453 uniprotkb:P32489 intact:EBI-5955|uniprotkb:D3DM88|ensemblfungi:YER179W intact:EBI-10685|uniprotkb:Q02946|ensemblfungi:YPL121C|uniprotkb:D6W3P6 psi-mi:dmc1_yeast(display_long)|uniprotkb:YER179W(locus name)|uniprotkb:DMC1(gene name)|psi-mi:DMC1(display_short)|uniprotkb:ISC2(gene name synonym) psi-mi:mei5_yeast(display_long)|uniprotkb:LPH6C(orf name)|uniprotkb:YPL121C(locus name)|uniprotkb:MEI5(gene name)|psi-mi:MEI5(display_short) psi-mi:"MI:0416"(fluorescence microscopy) Cho et al. (2016) pubmed:15620352|imex:IM-26190 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-16412463|imex:IM-26190-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011106.1|sgd:S000000981|dip:DIP-110N|mint:P25453|ensemblfungi:YER179W(gene)|ensemblfungi:YER179W_mRNA(transcript)|go:"GO:0000150"(DNA strand exchange activity)|go:"GO:0000709"(meiotic joint molecule formation)|go:"GO:0000730"(DNA recombinase assembly)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006312"(mitotic recombination)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0042030"(ATPase inhibitor activity)|go:"GO:0042148"(strand invasion)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070192"(chromosome organization involved in meiotic cell cycle)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010995(DNA repair Rad51/transcription factor NusA, alpha-helical)|interpro:IPR011940(Meiotic recombinase Dmc1)|interpro:IPR013632(Rad51, C-terminal)|interpro:IPR016467(DNA repair and recombination, RecA-like)|interpro:IPR020587|interpro:IPR020588|interpro:IPR027417|interpro:IPR033925 sgd:S000006042|refseq:NP_015204.1|ensemblfungi:YPL121C_mRNA(transcript)|go:"GO:0000707"(meiotic DNA recombinase assembly)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0007131"(reciprocal meiotic recombination)|ensemblfungi:YPL121C(gene)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|interpro:IPR018468|dip:DIP-2964N go:"GO:0000228"(nuclear chromosome) crc64:00B0503D7FAF5CB3 - figure legend:Fig. 3B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/09/06 2017/09/06 rogid:tbn7/STS08gIJBzfUmIz/yPmBJ8559292 rogid:cfOJ3UpLUhyxWrmLUJxFmWiKZZM559292 rigid:NsjtvrJBHrPu8UCoy22kAZmNdJU false - flag tag:c-c - - psi-mi:"MI:1200"(immunocytochemistry) psi-mi:"MI:1200"(immunocytochemistry) uniprotkb:P89114 uniprotkb:P32489 intact:EBI-16412526|ensemblfungi:YHR079C-A|uniprotkb:D3DL30 intact:EBI-10685|uniprotkb:Q02946|ensemblfungi:YPL121C|uniprotkb:D6W3P6 psi-mi:sae3_yeast(display_long)|uniprotkb:SAE3(gene name)|psi-mi:SAE3(display_short)|uniprotkb:Sporulation in the absence of SPO11 protein 3(gene name synonym)|uniprotkb:YHR079C-A(locus name) psi-mi:mei5_yeast(display_long)|uniprotkb:LPH6C(orf name)|uniprotkb:YPL121C(locus name)|uniprotkb:MEI5(gene name)|psi-mi:MEI5(display_short) psi-mi:"MI:0416"(fluorescence microscopy) Cho et al. (2016) pubmed:15620352|imex:IM-26190 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-16412548|imex:IM-26190-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YHR079C-A(gene)|ensemblfungi:YHR079C-A_mRNA(transcript)|go:"GO:0000707"(meiotic DNA recombinase assembly)|go:"GO:0000709"(meiotic joint molecule formation)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0010772"(meiotic DNA recombinase assembly involved in reciprocal meiotic recombination)|go:"GO:0032798"(Swi5-Sfr1 complex)|go:"GO:0034974"(Swi5-Swi2 complex)|interpro:IPR010760(Protein of unknown function DUF1337)|dip:DIP-5100N|refseq:NP_011947.2|sgd:S000001957 sgd:S000006042|refseq:NP_015204.1|ensemblfungi:YPL121C_mRNA(transcript)|go:"GO:0000707"(meiotic DNA recombinase assembly)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0007131"(reciprocal meiotic recombination)|ensemblfungi:YPL121C(gene)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|interpro:IPR018468|dip:DIP-2964N go:"GO:0000228"(nuclear chromosome) - - figure legend:Fig. 5D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/09/06 2017/09/06 rogid:hPxccktemX46/HLbUVWLFlsmAkM559292 rogid:cfOJ3UpLUhyxWrmLUJxFmWiKZZM559292 rigid:vNPNnkH2YVq6jAEtwEl6jv0j4p0 false flag tag:c-c - - - psi-mi:"MI:1200"(immunocytochemistry) psi-mi:"MI:1200"(immunocytochemistry) uniprotkb:P89114 uniprotkb:P25453 intact:EBI-16412526|ensemblfungi:YHR079C-A|uniprotkb:D3DL30 intact:EBI-5955|uniprotkb:D3DM88|ensemblfungi:YER179W psi-mi:sae3_yeast(display_long)|uniprotkb:SAE3(gene name)|psi-mi:SAE3(display_short)|uniprotkb:Sporulation in the absence of SPO11 protein 3(gene name synonym)|uniprotkb:YHR079C-A(locus name) psi-mi:dmc1_yeast(display_long)|uniprotkb:YER179W(locus name)|uniprotkb:DMC1(gene name)|psi-mi:DMC1(display_short)|uniprotkb:ISC2(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Cho et al. (2016) pubmed:15620352|imex:IM-26190 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-16420061|imex:IM-26190-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YHR079C-A(gene)|ensemblfungi:YHR079C-A_mRNA(transcript)|go:"GO:0000707"(meiotic DNA recombinase assembly)|go:"GO:0000709"(meiotic joint molecule formation)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0010772"(meiotic DNA recombinase assembly involved in reciprocal meiotic recombination)|go:"GO:0032798"(Swi5-Sfr1 complex)|go:"GO:0034974"(Swi5-Swi2 complex)|interpro:IPR010760(Protein of unknown function DUF1337)|dip:DIP-5100N|refseq:NP_011947.2|sgd:S000001957 refseq:NP_011106.1|sgd:S000000981|dip:DIP-110N|mint:P25453|ensemblfungi:YER179W(gene)|ensemblfungi:YER179W_mRNA(transcript)|go:"GO:0000150"(DNA strand exchange activity)|go:"GO:0000709"(meiotic joint molecule formation)|go:"GO:0000730"(DNA recombinase assembly)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006312"(mitotic recombination)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0042030"(ATPase inhibitor activity)|go:"GO:0042148"(strand invasion)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070192"(chromosome organization involved in meiotic cell cycle)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010995(DNA repair Rad51/transcription factor NusA, alpha-helical)|interpro:IPR011940(Meiotic recombinase Dmc1)|interpro:IPR013632(Rad51, C-terminal)|interpro:IPR016467(DNA repair and recombination, RecA-like)|interpro:IPR020587|interpro:IPR020588|interpro:IPR027417|interpro:IPR033925 go:"GO:0000228"(nuclear chromosome) - crc64:00B0503D7FAF5CB3 figure legend:Fig. 5Di|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/09/06 2017/09/25 rogid:hPxccktemX46/HLbUVWLFlsmAkM559292 rogid:tbn7/STS08gIJBzfUmIz/yPmBJ8559292 rigid:zE8zk66ceX0jxZ5wEgZq6KE4Pas false flag tag:c-c - - - psi-mi:"MI:1200"(immunocytochemistry) psi-mi:"MI:1200"(immunocytochemistry) uniprotkb:P25453 uniprotkb:P32489 intact:EBI-5955|uniprotkb:D3DM88|ensemblfungi:YER179W intact:EBI-10685|uniprotkb:Q02946|ensemblfungi:YPL121C|uniprotkb:D6W3P6 psi-mi:dmc1_yeast(display_long)|uniprotkb:YER179W(locus name)|uniprotkb:DMC1(gene name)|psi-mi:DMC1(display_short)|uniprotkb:ISC2(gene name synonym) psi-mi:mei5_yeast(display_long)|uniprotkb:LPH6C(orf name)|uniprotkb:YPL121C(locus name)|uniprotkb:MEI5(gene name)|psi-mi:MEI5(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Cho et al. (2016) pubmed:15620352|imex:IM-26190 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-16412475|imex:IM-26190-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011106.1|sgd:S000000981|dip:DIP-110N|mint:P25453|ensemblfungi:YER179W(gene)|ensemblfungi:YER179W_mRNA(transcript)|go:"GO:0000150"(DNA strand exchange activity)|go:"GO:0000709"(meiotic joint molecule formation)|go:"GO:0000730"(DNA recombinase assembly)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006312"(mitotic recombination)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0042030"(ATPase inhibitor activity)|go:"GO:0042148"(strand invasion)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070192"(chromosome organization involved in meiotic cell cycle)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010995(DNA repair Rad51/transcription factor NusA, alpha-helical)|interpro:IPR011940(Meiotic recombinase Dmc1)|interpro:IPR013632(Rad51, C-terminal)|interpro:IPR016467(DNA repair and recombination, RecA-like)|interpro:IPR020587|interpro:IPR020588|interpro:IPR027417|interpro:IPR033925 sgd:S000006042|refseq:NP_015204.1|ensemblfungi:YPL121C_mRNA(transcript)|go:"GO:0000707"(meiotic DNA recombinase assembly)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0007131"(reciprocal meiotic recombination)|ensemblfungi:YPL121C(gene)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|interpro:IPR018468|dip:DIP-2964N go:"GO:0051321"(meiotic cell cycle) crc64:00B0503D7FAF5CB3 - figure legend:Fig.4B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/09/06 2017/09/06 rogid:tbn7/STS08gIJBzfUmIz/yPmBJ8559292 rogid:cfOJ3UpLUhyxWrmLUJxFmWiKZZM559292 rigid:NsjtvrJBHrPu8UCoy22kAZmNdJU false - flag tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P89114 uniprotkb:P32489 intact:EBI-16412526|ensemblfungi:YHR079C-A|uniprotkb:D3DL30 intact:EBI-10685|uniprotkb:Q02946|ensemblfungi:YPL121C|uniprotkb:D6W3P6 psi-mi:sae3_yeast(display_long)|uniprotkb:SAE3(gene name)|psi-mi:SAE3(display_short)|uniprotkb:Sporulation in the absence of SPO11 protein 3(gene name synonym)|uniprotkb:YHR079C-A(locus name) psi-mi:mei5_yeast(display_long)|uniprotkb:LPH6C(orf name)|uniprotkb:YPL121C(locus name)|uniprotkb:MEI5(gene name)|psi-mi:MEI5(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Cho et al. (2016) pubmed:15620352|imex:IM-26190 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-16412531|imex:IM-26190-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YHR079C-A(gene)|ensemblfungi:YHR079C-A_mRNA(transcript)|go:"GO:0000707"(meiotic DNA recombinase assembly)|go:"GO:0000709"(meiotic joint molecule formation)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0010772"(meiotic DNA recombinase assembly involved in reciprocal meiotic recombination)|go:"GO:0032798"(Swi5-Sfr1 complex)|go:"GO:0034974"(Swi5-Swi2 complex)|interpro:IPR010760(Protein of unknown function DUF1337)|dip:DIP-5100N|refseq:NP_011947.2|sgd:S000001957 sgd:S000006042|refseq:NP_015204.1|ensemblfungi:YPL121C_mRNA(transcript)|go:"GO:0000707"(meiotic DNA recombinase assembly)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0007131"(reciprocal meiotic recombination)|ensemblfungi:YPL121C(gene)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|interpro:IPR018468|dip:DIP-2964N go:"GO:0000228"(nuclear chromosome) - - figure legend:Fig. 6A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/09/06 2017/09/06 rogid:hPxccktemX46/HLbUVWLFlsmAkM559292 rogid:cfOJ3UpLUhyxWrmLUJxFmWiKZZM559292 rigid:vNPNnkH2YVq6jAEtwEl6jv0j4p0 false flag tag:c-c - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P25453 uniprotkb:P32489 intact:EBI-5955|uniprotkb:D3DM88|ensemblfungi:YER179W intact:EBI-10685|uniprotkb:Q02946|ensemblfungi:YPL121C|uniprotkb:D6W3P6 psi-mi:dmc1_yeast(display_long)|uniprotkb:YER179W(locus name)|uniprotkb:DMC1(gene name)|psi-mi:DMC1(display_short)|uniprotkb:ISC2(gene name synonym) psi-mi:mei5_yeast(display_long)|uniprotkb:LPH6C(orf name)|uniprotkb:YPL121C(locus name)|uniprotkb:MEI5(gene name)|psi-mi:MEI5(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cho et al. (2016) pubmed:15620352|imex:IM-26190 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-16412488|imex:IM-26190-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011106.1|sgd:S000000981|dip:DIP-110N|mint:P25453|ensemblfungi:YER179W(gene)|ensemblfungi:YER179W_mRNA(transcript)|go:"GO:0000150"(DNA strand exchange activity)|go:"GO:0000709"(meiotic joint molecule formation)|go:"GO:0000730"(DNA recombinase assembly)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006312"(mitotic recombination)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0042030"(ATPase inhibitor activity)|go:"GO:0042148"(strand invasion)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070192"(chromosome organization involved in meiotic cell cycle)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010995(DNA repair Rad51/transcription factor NusA, alpha-helical)|interpro:IPR011940(Meiotic recombinase Dmc1)|interpro:IPR013632(Rad51, C-terminal)|interpro:IPR016467(DNA repair and recombination, RecA-like)|interpro:IPR020587|interpro:IPR020588|interpro:IPR027417|interpro:IPR033925 sgd:S000006042|refseq:NP_015204.1|ensemblfungi:YPL121C_mRNA(transcript)|go:"GO:0000707"(meiotic DNA recombinase assembly)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0007131"(reciprocal meiotic recombination)|ensemblfungi:YPL121C(gene)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|interpro:IPR018468|dip:DIP-2964N go:"GO:0051321"(meiotic cell cycle) crc64:00B0503D7FAF5CB3 - figure legend:Fig.4B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/09/06 2017/09/06 rogid:tbn7/STS08gIJBzfUmIz/yPmBJ8559292 rogid:cfOJ3UpLUhyxWrmLUJxFmWiKZZM559292 rigid:NsjtvrJBHrPu8UCoy22kAZmNdJU false - flag tag:c-c - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P25453 uniprotkb:P32489 intact:EBI-5955|uniprotkb:D3DM88|ensemblfungi:YER179W intact:EBI-10685|uniprotkb:Q02946|ensemblfungi:YPL121C|uniprotkb:D6W3P6 psi-mi:dmc1_yeast(display_long)|uniprotkb:YER179W(locus name)|uniprotkb:DMC1(gene name)|psi-mi:DMC1(display_short)|uniprotkb:ISC2(gene name synonym) psi-mi:mei5_yeast(display_long)|uniprotkb:LPH6C(orf name)|uniprotkb:YPL121C(locus name)|uniprotkb:MEI5(gene name)|psi-mi:MEI5(display_short) psi-mi:"MI:0018"(two hybrid) Cho et al. (2016) pubmed:15620352|imex:IM-26190 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-16412507|imex:IM-26190-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011106.1|sgd:S000000981|dip:DIP-110N|mint:P25453|ensemblfungi:YER179W(gene)|ensemblfungi:YER179W_mRNA(transcript)|go:"GO:0000150"(DNA strand exchange activity)|go:"GO:0000709"(meiotic joint molecule formation)|go:"GO:0000730"(DNA recombinase assembly)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006312"(mitotic recombination)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0042030"(ATPase inhibitor activity)|go:"GO:0042148"(strand invasion)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070192"(chromosome organization involved in meiotic cell cycle)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010995(DNA repair Rad51/transcription factor NusA, alpha-helical)|interpro:IPR011940(Meiotic recombinase Dmc1)|interpro:IPR013632(Rad51, C-terminal)|interpro:IPR016467(DNA repair and recombination, RecA-like)|interpro:IPR020587|interpro:IPR020588|interpro:IPR027417|interpro:IPR033925 sgd:S000006042|refseq:NP_015204.1|ensemblfungi:YPL121C_mRNA(transcript)|go:"GO:0000707"(meiotic DNA recombinase assembly)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0007131"(reciprocal meiotic recombination)|ensemblfungi:YPL121C(gene)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|interpro:IPR018468|dip:DIP-2964N go:"GO:0000228"(nuclear chromosome) crc64:00B0503D7FAF5CB3 - figure legend:Fig. 4C, 4D|comment:Full-length Mei5 protein did not interact with full-length Dmc1 in this assay|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/09/06 2017/09/06 rogid:tbn7/STS08gIJBzfUmIz/yPmBJ8559292 rogid:cfOJ3UpLUhyxWrmLUJxFmWiKZZM559292 rigid:NsjtvrJBHrPu8UCoy22kAZmNdJU false - sufficient binding region:1-123 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P89114 uniprotkb:P32489 intact:EBI-16412526|ensemblfungi:YHR079C-A|uniprotkb:D3DL30 intact:EBI-10685|uniprotkb:Q02946|ensemblfungi:YPL121C|uniprotkb:D6W3P6 psi-mi:sae3_yeast(display_long)|uniprotkb:SAE3(gene name)|psi-mi:SAE3(display_short)|uniprotkb:Sporulation in the absence of SPO11 protein 3(gene name synonym)|uniprotkb:YHR079C-A(locus name) psi-mi:mei5_yeast(display_long)|uniprotkb:LPH6C(orf name)|uniprotkb:YPL121C(locus name)|uniprotkb:MEI5(gene name)|psi-mi:MEI5(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Cho et al. (2016) pubmed:15620352|imex:IM-26190 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-16412524|imex:IM-26190-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YHR079C-A(gene)|ensemblfungi:YHR079C-A_mRNA(transcript)|go:"GO:0000707"(meiotic DNA recombinase assembly)|go:"GO:0000709"(meiotic joint molecule formation)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0010772"(meiotic DNA recombinase assembly involved in reciprocal meiotic recombination)|go:"GO:0032798"(Swi5-Sfr1 complex)|go:"GO:0034974"(Swi5-Swi2 complex)|interpro:IPR010760(Protein of unknown function DUF1337)|dip:DIP-5100N|refseq:NP_011947.2|sgd:S000001957 sgd:S000006042|refseq:NP_015204.1|ensemblfungi:YPL121C_mRNA(transcript)|go:"GO:0000707"(meiotic DNA recombinase assembly)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0007131"(reciprocal meiotic recombination)|ensemblfungi:YPL121C(gene)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|interpro:IPR018468|dip:DIP-2964N - - - figure legend:Fig. 6A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/09/06 2017/09/25 rogid:hPxccktemX46/HLbUVWLFlsmAkM559292 rogid:cfOJ3UpLUhyxWrmLUJxFmWiKZZM559292 rigid:vNPNnkH2YVq6jAEtwEl6jv0j4p0 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P89114 uniprotkb:P32489 intact:EBI-16412526|ensemblfungi:YHR079C-A|uniprotkb:D3DL30 intact:EBI-10685|uniprotkb:Q02946|ensemblfungi:YPL121C|uniprotkb:D6W3P6 psi-mi:sae3_yeast(display_long)|uniprotkb:SAE3(gene name)|psi-mi:SAE3(display_short)|uniprotkb:Sporulation in the absence of SPO11 protein 3(gene name synonym)|uniprotkb:YHR079C-A(locus name) psi-mi:mei5_yeast(display_long)|uniprotkb:LPH6C(orf name)|uniprotkb:YPL121C(locus name)|uniprotkb:MEI5(gene name)|psi-mi:MEI5(display_short) psi-mi:"MI:0226"(ion exchange chromatography) Cho et al. (2016) pubmed:15620352|imex:IM-26190 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-16420135|imex:IM-26190-17 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YHR079C-A(gene)|ensemblfungi:YHR079C-A_mRNA(transcript)|go:"GO:0000707"(meiotic DNA recombinase assembly)|go:"GO:0000709"(meiotic joint molecule formation)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0010772"(meiotic DNA recombinase assembly involved in reciprocal meiotic recombination)|go:"GO:0032798"(Swi5-Sfr1 complex)|go:"GO:0034974"(Swi5-Swi2 complex)|interpro:IPR010760(Protein of unknown function DUF1337)|dip:DIP-5100N|refseq:NP_011947.2|sgd:S000001957 sgd:S000006042|refseq:NP_015204.1|ensemblfungi:YPL121C_mRNA(transcript)|go:"GO:0000707"(meiotic DNA recombinase assembly)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0007131"(reciprocal meiotic recombination)|ensemblfungi:YPL121C(gene)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|interpro:IPR018468|dip:DIP-2964N - - - figure legend:Fig. 6B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2017/09/06 2017/09/26 rogid:hPxccktemX46/HLbUVWLFlsmAkM559292 rogid:cfOJ3UpLUhyxWrmLUJxFmWiKZZM559292 rigid:vNPNnkH2YVq6jAEtwEl6jv0j4p0 false - - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)