#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:F1PLD0 uniprotkb:Q9MZF4 intact:EBI-12740728|ensembl:ENSCAFP00000027874 intact:EBI-12740747|ensembl:ENSCAFP00000020209 psi-mi:f1pld0_canlf(display_long)|uniprotkb:TXNDC11(gene name)|psi-mi:TXNDC11(display_short) psi-mi:duox1_canlf(display_long)|uniprotkb:DUOX1(gene name)|psi-mi:DUOX1(display_short)|uniprotkb:THOX1(gene name synonym)|uniprotkb:NADPH thyroid oxidase 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Wang et al. (2005) pubmed:15561711|imex:IM-25649 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-12740742|imex:IM-25649-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000018890(gene)|ensembl:ENSCAFT00000029994(transcript)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR036249|refseq:XP_005621591.1 ensembl:ENSCAFG00000013715(gene)|ensembl:ENSCAFT00000021757(transcript)|go:"GO:0004601"(peroxidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006590"(thyroid hormone generation)|go:"GO:0006952"(defense response)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0009986"(cell surface)|go:"GO:0016174"("NAD(P)H oxidase H2O2-forming activity")|go:"GO:0016175"("superoxide-generating NAD(P)H oxidase activity")|go:"GO:0050661"(NADP binding)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0050665"(hydrogen peroxide biosynthetic process)|go:"GO:0051591"(response to cAMP)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0106293"(NADH oxidase H202-forming activity)|go:"GO:0106294"(NADPH oxidase H202-forming activity)|go:"GO:2000147"(positive regulation of cell motility)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR010255(Haem peroxidase)|interpro:IPR011992(EF-Hand type)|interpro:IPR013112(FAD-binding 8)|interpro:IPR013121(Ferric reductase, NAD binding)|interpro:IPR013130(Ferric reductase-like transmembrane component, N-terminal)|interpro:IPR017927|interpro:IPR017938|interpro:IPR018247|interpro:IPR019791|interpro:IPR029595|interpro:IPR034821|interpro:IPR037120|interpro:IPR039261|reactome:R-CFA-209968|go:"GO:0020037"(heme binding)|go:"GO:0031252"(cell leading edge)|go:"GO:0042335"(cuticle development)|go:"GO:0042446"(hormone biosynthetic process)|go:"GO:0042554"(superoxide anion generation)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0043020"(NADPH oxidase complex)|refseq:NP_001003122.1|refseq:XP_005638229.1|refseq:XP_005638230.1|refseq:XP_013964813.1 - - - figure legend:no figure|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/19 2020/01/08 rogid:j2a4+ZCC6ko4WJcrQAHw1WUax4s9615 rogid:yHsXZxXIQVB8UjMw26SrvkumUz09615 rigid:1Kul3XI0a1pA3774jyX5RAl2Tv8 false sufficient binding region:681-811 sufficient binding region:616-1043 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:F1PLD0 uniprotkb:Q9MZF4 intact:EBI-12740728|ensembl:ENSCAFP00000027874 intact:EBI-12740747|ensembl:ENSCAFP00000020209 psi-mi:f1pld0_canlf(display_long)|uniprotkb:TXNDC11(gene name)|psi-mi:TXNDC11(display_short) psi-mi:duox1_canlf(display_long)|uniprotkb:DUOX1(gene name)|psi-mi:DUOX1(display_short)|uniprotkb:THOX1(gene name synonym)|uniprotkb:NADPH thyroid oxidase 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Wang et al. (2005) pubmed:15561711|imex:IM-25649 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-12740801|imex:IM-25649-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000018890(gene)|ensembl:ENSCAFT00000029994(transcript)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR036249|refseq:XP_005621591.1 ensembl:ENSCAFG00000013715(gene)|ensembl:ENSCAFT00000021757(transcript)|go:"GO:0004601"(peroxidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006590"(thyroid hormone generation)|go:"GO:0006952"(defense response)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0009986"(cell surface)|go:"GO:0016174"("NAD(P)H oxidase H2O2-forming activity")|go:"GO:0016175"("superoxide-generating NAD(P)H oxidase activity")|go:"GO:0050661"(NADP binding)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0050665"(hydrogen peroxide biosynthetic process)|go:"GO:0051591"(response to cAMP)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0106293"(NADH oxidase H202-forming activity)|go:"GO:0106294"(NADPH oxidase H202-forming activity)|go:"GO:2000147"(positive regulation of cell motility)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR010255(Haem peroxidase)|interpro:IPR011992(EF-Hand type)|interpro:IPR013112(FAD-binding 8)|interpro:IPR013121(Ferric reductase, NAD binding)|interpro:IPR013130(Ferric reductase-like transmembrane component, N-terminal)|interpro:IPR017927|interpro:IPR017938|interpro:IPR018247|interpro:IPR019791|interpro:IPR029595|interpro:IPR034821|interpro:IPR037120|interpro:IPR039261|reactome:R-CFA-209968|go:"GO:0020037"(heme binding)|go:"GO:0031252"(cell leading edge)|go:"GO:0042335"(cuticle development)|go:"GO:0042446"(hormone biosynthetic process)|go:"GO:0042554"(superoxide anion generation)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0043020"(NADPH oxidase complex)|refseq:NP_001003122.1|refseq:XP_005638229.1|refseq:XP_005638230.1|refseq:XP_013964813.1 - - - figure legend:1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/19 2020/01/08 rogid:j2a4+ZCC6ko4WJcrQAHw1WUax4s9615 rogid:yHsXZxXIQVB8UjMw26SrvkumUz09615 rigid:1Kul3XI0a1pA3774jyX5RAl2Tv8 false sufficient binding region:681-811 sufficient binding region:616-1043 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:F1PLD0 uniprotkb:Q9NRD9 intact:EBI-12740728|ensembl:ENSCAFP00000027874 intact:EBI-6677285|ensembl:ENSP00000317997|ensembl:ENSP00000373689|uniprotkb:A6NH28|uniprotkb:Q14C94|uniprotkb:Q6ZMB3|uniprotkb:Q6ZR09|uniprotkb:Q9NZC1 psi-mi:f1pld0_canlf(display_long)|uniprotkb:TXNDC11(gene name)|psi-mi:TXNDC11(display_short) psi-mi:duox1_human(display_long)|uniprotkb:DUOX1(gene name)|psi-mi:DUOX1(display_short)|uniprotkb:DUOX(gene name synonym)|uniprotkb:LNOX1(gene name synonym)|uniprotkb:THOX1(gene name synonym)|uniprotkb:Large NOX 1(gene name synonym)|uniprotkb:Long NOX 1(gene name synonym)|uniprotkb:NADPH thyroid oxidase 1(gene name synonym)|uniprotkb:Thyroid oxidase 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Wang et al. (2005) pubmed:15561711|imex:IM-25649 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-12740832|imex:IM-25649-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000018890(gene)|ensembl:ENSCAFT00000029994(transcript)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR036249|refseq:XP_005621591.1 ensembl:ENSG00000137857(gene)|ensembl:ENST00000321429(transcript)|ensembl:ENST00000389037(transcript)|go:"GO:0004601"(peroxidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006590"(thyroid hormone generation)|go:"GO:0006952"(defense response)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0009986"(cell surface)|go:"GO:0016174"("NAD(P)H oxidase H2O2-forming activity")|go:"GO:0016175"("superoxide-generating NAD(P)H oxidase activity")|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0020037"(heme binding)|go:"GO:0031252"(cell leading edge)|go:"GO:0042335"(cuticle development)|go:"GO:0042446"(hormone biosynthetic process)|go:"GO:0042554"(superoxide anion generation)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0043020"(NADPH oxidase complex)|go:"GO:0050661"(NADP binding)|go:"GO:0050665"(hydrogen peroxide biosynthetic process)|go:"GO:0051591"(response to cAMP)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0106293"(NADH oxidase H202-forming activity)|go:"GO:0106294"(NADPH oxidase H202-forming activity)|go:"GO:2000147"(positive regulation of cell motility)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR010255(Haem peroxidase)|interpro:IPR011992(EF-Hand type)|interpro:IPR013112(FAD-binding 8)|interpro:IPR013121(Ferric reductase, NAD binding)|interpro:IPR013130(Ferric reductase-like transmembrane component, N-terminal)|interpro:IPR017927|interpro:IPR017938|interpro:IPR018247|interpro:IPR019791|interpro:IPR029595|interpro:IPR034821|interpro:IPR037120|interpro:IPR039261|rcsb pdb:7D3E|rcsb pdb:7D3F|reactome:R-HSA-209968|refseq:XP_011519984.1|refseq:NP_059130.2|refseq:NP_787954.1 - - - figure legend:1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/01/19 2020/01/08 rogid:j2a4+ZCC6ko4WJcrQAHw1WUax4s9615 rogid:8kuQuOkttH16Rfv0TzxsVLGZQSk9606 rigid:rKpRFuf9zy0vs4azAvWCZiocSFo false sufficient binding region:681-811 sufficient binding region:616-1043 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6PKC3 uniprotkb:Q9NRD9 intact:EBI-749812|uniprotkb:O95887|uniprotkb:Q6PJA6|uniprotkb:Q8N2Q4|uniprotkb:Q96K45|uniprotkb:Q96K53|ensembl:ENSP00000349439 intact:EBI-6677285|ensembl:ENSP00000317997|ensembl:ENSP00000373689|uniprotkb:A6NH28|uniprotkb:Q14C94|uniprotkb:Q6ZMB3|uniprotkb:Q6ZR09|uniprotkb:Q9NZC1 psi-mi:txd11_human(display_long)|uniprotkb:EF-hand-binding protein 1(gene name synonym)|uniprotkb:TXNDC11(gene name)|psi-mi:TXNDC11(display_short)|uniprotkb:EFP1(gene name synonym) psi-mi:duox1_human(display_long)|uniprotkb:DUOX1(gene name)|psi-mi:DUOX1(display_short)|uniprotkb:DUOX(gene name synonym)|uniprotkb:LNOX1(gene name synonym)|uniprotkb:THOX1(gene name synonym)|uniprotkb:Large NOX 1(gene name synonym)|uniprotkb:Long NOX 1(gene name synonym)|uniprotkb:NADPH thyroid oxidase 1(gene name synonym)|uniprotkb:Thyroid oxidase 1(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) Wang et al. (2005) pubmed:15561711|imex:IM-25649 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-12740852|imex:IM-25649-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056998.4|refseq:NP_001290376.1|refseq:NP_001310953.1|refseq:NP_001310954.1|ensembl:ENSG00000153066(gene)|ensembl:ENST00000356957(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR036249 ensembl:ENSG00000137857(gene)|ensembl:ENST00000321429(transcript)|ensembl:ENST00000389037(transcript)|go:"GO:0004601"(peroxidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006590"(thyroid hormone generation)|go:"GO:0006952"(defense response)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0009986"(cell surface)|go:"GO:0016174"("NAD(P)H oxidase H2O2-forming activity")|go:"GO:0016175"("superoxide-generating NAD(P)H oxidase activity")|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0020037"(heme binding)|go:"GO:0031252"(cell leading edge)|go:"GO:0042335"(cuticle development)|go:"GO:0042446"(hormone biosynthetic process)|go:"GO:0042554"(superoxide anion generation)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0043020"(NADPH oxidase complex)|go:"GO:0050661"(NADP binding)|go:"GO:0050665"(hydrogen peroxide biosynthetic process)|go:"GO:0051591"(response to cAMP)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0106293"(NADH oxidase H202-forming activity)|go:"GO:0106294"(NADPH oxidase H202-forming activity)|go:"GO:2000147"(positive regulation of cell motility)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR010255(Haem peroxidase)|interpro:IPR011992(EF-Hand type)|interpro:IPR013112(FAD-binding 8)|interpro:IPR013121(Ferric reductase, NAD binding)|interpro:IPR013130(Ferric reductase-like transmembrane component, N-terminal)|interpro:IPR017927|interpro:IPR017938|interpro:IPR018247|interpro:IPR019791|interpro:IPR029595|interpro:IPR034821|interpro:IPR037120|interpro:IPR039261|rcsb pdb:7D3E|rcsb pdb:7D3F|reactome:R-HSA-209968|refseq:XP_011519984.1|refseq:NP_059130.2|refseq:NP_787954.1 - - - figure legend:5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos)|taxid:9534(Chlorocebus aethiops) - 2017/01/19 2017/01/19 rogid:IQd9IIZUolw+gL+g/pwwTZaqtf49606 rogid:8kuQuOkttH16Rfv0TzxsVLGZQSk9606 rigid:3ozL2JEmZZwQGrB77SuXku5QuBE false his tag:?-? - - - psi-mi:"MI:0707"(anti tag immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q6PKC3 uniprotkb:Q9NRD9 intact:EBI-749812|uniprotkb:O95887|uniprotkb:Q6PJA6|uniprotkb:Q8N2Q4|uniprotkb:Q96K45|uniprotkb:Q96K53|ensembl:ENSP00000349439 intact:EBI-6677285|ensembl:ENSP00000317997|ensembl:ENSP00000373689|uniprotkb:A6NH28|uniprotkb:Q14C94|uniprotkb:Q6ZMB3|uniprotkb:Q6ZR09|uniprotkb:Q9NZC1 psi-mi:txd11_human(display_long)|uniprotkb:EF-hand-binding protein 1(gene name synonym)|uniprotkb:TXNDC11(gene name)|psi-mi:TXNDC11(display_short)|uniprotkb:EFP1(gene name synonym) psi-mi:duox1_human(display_long)|uniprotkb:DUOX1(gene name)|psi-mi:DUOX1(display_short)|uniprotkb:DUOX(gene name synonym)|uniprotkb:LNOX1(gene name synonym)|uniprotkb:THOX1(gene name synonym)|uniprotkb:Large NOX 1(gene name synonym)|uniprotkb:Long NOX 1(gene name synonym)|uniprotkb:NADPH thyroid oxidase 1(gene name synonym)|uniprotkb:Thyroid oxidase 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Wang et al. (2005) pubmed:15561711|imex:IM-25649 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-12740871|imex:IM-25649-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056998.4|refseq:NP_001290376.1|refseq:NP_001310953.1|refseq:NP_001310954.1|ensembl:ENSG00000153066(gene)|ensembl:ENST00000356957(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR036249 ensembl:ENSG00000137857(gene)|ensembl:ENST00000321429(transcript)|ensembl:ENST00000389037(transcript)|go:"GO:0004601"(peroxidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006590"(thyroid hormone generation)|go:"GO:0006952"(defense response)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0009986"(cell surface)|go:"GO:0016174"("NAD(P)H oxidase H2O2-forming activity")|go:"GO:0016175"("superoxide-generating NAD(P)H oxidase activity")|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0020037"(heme binding)|go:"GO:0031252"(cell leading edge)|go:"GO:0042335"(cuticle development)|go:"GO:0042446"(hormone biosynthetic process)|go:"GO:0042554"(superoxide anion generation)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0043020"(NADPH oxidase complex)|go:"GO:0050661"(NADP binding)|go:"GO:0050665"(hydrogen peroxide biosynthetic process)|go:"GO:0051591"(response to cAMP)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0106293"(NADH oxidase H202-forming activity)|go:"GO:0106294"(NADPH oxidase H202-forming activity)|go:"GO:2000147"(positive regulation of cell motility)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR010255(Haem peroxidase)|interpro:IPR011992(EF-Hand type)|interpro:IPR013112(FAD-binding 8)|interpro:IPR013121(Ferric reductase, NAD binding)|interpro:IPR013130(Ferric reductase-like transmembrane component, N-terminal)|interpro:IPR017927|interpro:IPR017938|interpro:IPR018247|interpro:IPR019791|interpro:IPR029595|interpro:IPR034821|interpro:IPR037120|interpro:IPR039261|rcsb pdb:7D3E|rcsb pdb:7D3F|reactome:R-HSA-209968|refseq:XP_011519984.1|refseq:NP_059130.2|refseq:NP_787954.1 - - - figure legend:6B abd C|comment:"Presence of EGTA or Ca(2+) or both does not affect association"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos)|taxid:9534(Chlorocebus aethiops) - 2017/01/19 2020/04/27 rogid:IQd9IIZUolw+gL+g/pwwTZaqtf49606 rogid:8kuQuOkttH16Rfv0TzxsVLGZQSk9606 rigid:3ozL2JEmZZwQGrB77SuXku5QuBE false his tag:?-? - - - psi-mi:"MI:0707"(anti tag immunostaining) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9NRD8 uniprotkb:Q6PKC3 intact:EBI-12740885|ensembl:ENSP00000475084|uniprotkb:A8MQ13|uniprotkb:D2XI64|uniprotkb:Q9NR02|uniprotkb:Q9UHF9 intact:EBI-749812|uniprotkb:O95887|uniprotkb:Q6PJA6|uniprotkb:Q8N2Q4|uniprotkb:Q96K45|uniprotkb:Q96K53|ensembl:ENSP00000349439 psi-mi:duox2_human(display_long)|uniprotkb:DUOX2(gene name)|psi-mi:DUOX2(display_short)|uniprotkb:LNOX2(gene name synonym)|uniprotkb:THOX2(gene name synonym)|uniprotkb:Large NOX 2(gene name synonym)|uniprotkb:Long NOX 2(gene name synonym)|uniprotkb:NADH/NADPH thyroid oxidase p138-tox(gene name synonym)|uniprotkb:NADPH oxidase/peroxidase DUOX2(gene name synonym)|uniprotkb:NADPH thyroid oxidase 2(gene name synonym)|uniprotkb:Thyroid oxidase 2(gene name synonym)|uniprotkb:p138 thyroid oxidase(gene name synonym) psi-mi:txd11_human(display_long)|uniprotkb:EF-hand-binding protein 1(gene name synonym)|uniprotkb:TXNDC11(gene name)|psi-mi:TXNDC11(display_short)|uniprotkb:EFP1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Wang et al. (2005) pubmed:15561711|imex:IM-25649 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-12740878|imex:IM-25649-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000140279(gene)|ensembl:ENST00000603300(transcript)|go:"GO:0004601"(peroxidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006590"(thyroid hormone generation)|go:"GO:0006952"(defense response)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0016174"("NAD(P)H oxidase H2O2-forming activity")|go:"GO:0016175"("superoxide-generating NAD(P)H oxidase activity")|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0020037"(heme binding)|go:"GO:0030054"(cell junction)|go:"GO:0031252"(cell leading edge)|go:"GO:0042335"(cuticle development)|go:"GO:0042446"(hormone biosynthetic process)|go:"GO:0042554"(superoxide anion generation)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0043020"(NADPH oxidase complex)|go:"GO:0045177"(apical part of cell)|go:"GO:0050665"(hydrogen peroxide biosynthetic process)|go:"GO:0051591"(response to cAMP)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0106293"(NADH oxidase H202-forming activity)|go:"GO:0106294"(NADPH oxidase H202-forming activity)|go:"GO:2000147"(positive regulation of cell motility)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR010255(Haem peroxidase)|interpro:IPR011992(EF-Hand type)|interpro:IPR013112(FAD-binding 8)|interpro:IPR013121(Ferric reductase, NAD binding)|interpro:IPR013130(Ferric reductase-like transmembrane component, N-terminal)|interpro:IPR017927|interpro:IPR017938|interpro:IPR018247|interpro:IPR019791|interpro:IPR034818|interpro:IPR034821|interpro:IPR037120|interpro:IPR039261|reactome:R-HSA-209968|refseq:NP_054799.4 refseq:NP_056998.4|refseq:NP_001290376.1|refseq:NP_001310953.1|refseq:NP_001310954.1|ensembl:ENSG00000153066(gene)|ensembl:ENST00000356957(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR036249 - - - figure legend:6B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos)|taxid:9534(Chlorocebus aethiops) - 2017/01/19 2020/04/27 rogid:CxjD4JIZ06U8HhY1yDN66mgp8T89606 rogid:IQd9IIZUolw+gL+g/pwwTZaqtf49606 rigid:LtI8G/VTYsQxpsg4f66wTgQ3W/Y false - his tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0707"(anti tag immunostaining)