#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
matrixdb:MULT_2_mouse	matrixdb:MULT_45_human	intact:EBI-16411794	intact:EBI-2528731	psi-mi:lam111-nid1_mouse(display_short)|psi-mi:MULT_2_mouse(display_long)|intact:"Lama1:Lamb1:Lamc1:Nid1"(complex systematic name)|intact:Laminin111-nidogen complex (complex recommended name)|intact:Laminin-entactin complex(complex synonym)|intact:Laminin111-nidogen1 complex(complex synonym)|intact:Laminin-nidogen complex(complex synonym)	psi-mi:collagen_xvii_human(display_short)|psi-mi:MULT_45_human(display_long)|intact:Collagen type XVII trimer(complex recommended name)|intact:Type XVII collagen(complex synonym)|intact:COL17A1 trimer(complex systematic name)	psi-mi:"MI:0892"(solid phase assay)	Tasanen et al. (2004)	pubmed:15161638|imex:IM-26142	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-16418305|imex:IM-26142-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:1302"(stable complex)	psi-mi:"MI:1302"(stable complex)	wwpdb:1NPE(subset)|go:"GO:0110011"(regulation of basement membrane organization)|go:"GO:0005509"(calcium ion binding)|pubmed:25387007(see-also)|pubmed:7556571(see-also)|pubmed:24727304(see-also)|pubmed:1350783(see-also)|go:"GO:0098637"(protein complex involved in cell-matrix adhesion)|pubmed:3109910(see-also)|go:"GO:0005604"(basement membrane)|go:"GO:0051149"(positive regulation of muscle cell differentiation)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:2001046"(positive regulation of integrin-mediated signaling pathway)|go:"GO:0005518"(collagen binding)|go:"GO:0005178"(integrin binding)|complex portal:CPX-1281(complex-primary)|go:"GO:0005201"(extracellular matrix structural constituent)|evidence ontology:"ECO:0005547"	pubmed:1916105(see-also)|pubmed:17876790(see-also)|go:"GO:0005198"(structural molecule activity)|evidence ontology:"ECO:0005547"|go:"GO:0030937"(collagen type XVII trimer)|complex portal:CPX-1758(complex-primary)	-	curated-complex:"An extracellular matrix complex responsible for basement membrane stabilization and cell-matrix adhesion. Crosslinking of the nidogen subunit from one complex to a laminin arm of a second by tissue transglutaminases forms large assemblies. Facilitates cell adhesion by binding collagens (e.g. collagen type I, CPX-2956 or collagen type IV, CPX-2959) and integrins (e.g. alpha3beta1, CPX-3117 or alphavbeta3, CPX-3035). May modify type I collagen scaffolds and thereby enhance myotube formation."|complex-properties:"Nidogen binds laminin epidermal-growth-factor-like (LE) modules via its six-bladed beta-propeller domain. Laminin-gamma1 Asn-835 is crucial for this interaction. The complex binds cell membrane proteins (e.g. integrins) via the nidogen subunit and the long arm of the laminin complex."|complex-assembly:Heterotetramer|curation request:Sylvie Ricard-Blum, MatrixDB	curated-complex:Nonfibrillar collagen that is a transmembrane protein. Collagen XVII is a structural component of hemidesmosomes, multiprotein complexes at the dermal-epidermal basement membrane zone that mediate adhesion of keratinocytes to the underlying membrane.|complex-assembly:Homotrimer.|complex-properties:Triple-helices consisting of about 1000 amino acids per chain forming a coiled coil structure. Each polypeptide forms a left-handed helix in which every third residue, glycine, comes into the centre of the superhelix.	figure legend:12A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/09/19	2017/09/19	-	-	-	false	-	sufficient binding region:1175-1497	-	-	psi-mi:"MI:0411"(enzyme linked immunosorbent assay)	psi-mi:"MI:0411"(enzyme linked immunosorbent assay)
matrixdb:MULT_45_human	matrixdb:MULT_30_VARA_human	intact:EBI-2528731	intact:EBI-2529819|reactome:R-HSA-216001|protein ontology:"PR:000027395"|reactome:R-HSA-2533911	psi-mi:collagen_xvii_human(display_short)|psi-mi:MULT_45_human(display_long)|intact:Collagen type XVII trimer(complex recommended name)|intact:Type XVII collagen(complex synonym)|intact:COL17A1 trimer(complex systematic name)	psi-mi:lm-332_human-a(display_short)|psi-mi:MULT_30_VARA_human(display_long)|intact:LM-5A(complex synonym)|intact:LM-3A32(complex synonym)|intact:Laminin-332 complex variant A(complex recommended name)|intact:LM-332(complex synonym)|intact:Laminin-5 complex(complex synonym)|intact:epiligrin(complex synonym)|intact:kalinin(complex synonym)|intact:nicein(complex synonym)|intact:"LAMA3:LAMB3:LAMC2"(complex systematic name)|intact:ladsin(complex synonym)	psi-mi:"MI:0892"(solid phase assay)	Tasanen et al. (2004)	pubmed:15161638|imex:IM-26142	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-16418311|imex:IM-26142-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:1302"(stable complex)	psi-mi:"MI:1302"(stable complex)	pubmed:1916105(see-also)|pubmed:17876790(see-also)|go:"GO:0005198"(structural molecule activity)|evidence ontology:"ECO:0005547"|go:"GO:0030937"(collagen type XVII trimer)|complex portal:CPX-1758(complex-primary)	pubmed:17453709(see-also)|go:"GO:0005610"(laminin-5 complex)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0030155"(regulation of cell adhesion)|evidence ontology:"ECO:0005547"|complex portal:CPX-1774(complex-primary)	-	curated-complex:Nonfibrillar collagen that is a transmembrane protein. Collagen XVII is a structural component of hemidesmosomes, multiprotein complexes at the dermal-epidermal basement membrane zone that mediate adhesion of keratinocytes to the underlying membrane.|complex-assembly:Homotrimer.|complex-properties:Triple-helices consisting of about 1000 amino acids per chain forming a coiled coil structure. Each polypeptide forms a left-handed helix in which every third residue, glycine, comes into the centre of the superhelix.	complex-properties:"Complex glycoprotein, consisting of three different polypeptide chains (alpha, beta, gamma), which are bound to each other by disulfide bonds into a cross-shaped molecule comprising one long and three short arms with globules at each end.     Laminin-332 variant B (CPX-3165) only differs from this complex by the length of the alpha chain isoform."|curated-complex:Major component of basment membranes which binds to cells via a high affinity, cell-surface receptor. Role in the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Laminin-5 is thought to be involved in cell adhesion via integrin alpha-3/beta-1 in focal adhesion and integrin alpha-6/beta-4 in hemidesmosomes, signal transduction via tyrosine phosphorylation of pp125-FAK and p80, differentiation of keratinocytes.|complex-assembly:Heterotrimer.	figure legend:12A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/09/19	2017/09/19	-	-	-	false	sufficient binding region:1175-1497	-	-	-	psi-mi:"MI:0411"(enzyme linked immunosorbent assay)	psi-mi:"MI:0411"(enzyme linked immunosorbent assay)