#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P32841	uniprotkb:P29467	intact:EBI-14447|uniprotkb:D6VZV6|ensemblfungi:YMR133W	intact:EBI-2566907|uniprotkb:P87265|uniprotkb:D3DLU5|ensemblfungi:YER044C-A	psi-mi:re114_yeast(display_long)|uniprotkb:YM9375.02(orf name)|uniprotkb:YMR133W(locus name)|uniprotkb:REC114(gene name)|psi-mi:REC114(display_short)	psi-mi:mei4_yeast(display_long)|uniprotkb:MEI4(gene name)|psi-mi:MEI4(display_short)|uniprotkb:YER044BC(orf name)|uniprotkb:YER044C-A(locus name)	psi-mi:"MI:0018"(two hybrid)	Arora et al. (2004)	imex:IM-26321|pubmed:14992724	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16715194|imex:IM-26321-41	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YMR133W(gene)|ensemblfungi:YMR133W_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0042138"(meiotic DNA double-strand break formation)|interpro:IPR004354(Meiotic recombination protein rec114)|refseq:NP_013852.1|sgd:S000004740|dip:DIP-4006N	sgd:S000001954|refseq:NP_010963.1|ensemblfungi:YER044C-A(gene)|ensemblfungi:YER044C-A_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0006310"(DNA recombination)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0042138"(meiotic DNA double-strand break formation)|interpro:IPR025888	-	-	-	figure legend:Supplementary table 1-1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/11/17	2017/12/21	rogid:Ct+5dpxGmczgKzWhEhiHiRuxPG4559292	rogid:A9neKqDQ4o5xP4QUOSRJQvJetnY559292	rigid:RT73VRxm81OWfXqTuP++oaHYEp4	false	gal4 activation domain:c-c	lexa dna binding domain:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32841	uniprotkb:P29467	intact:EBI-14447|uniprotkb:D6VZV6|ensemblfungi:YMR133W	intact:EBI-2566907|uniprotkb:P87265|uniprotkb:D3DLU5|ensemblfungi:YER044C-A	psi-mi:re114_yeast(display_long)|uniprotkb:YM9375.02(orf name)|uniprotkb:YMR133W(locus name)|uniprotkb:REC114(gene name)|psi-mi:REC114(display_short)	psi-mi:mei4_yeast(display_long)|uniprotkb:MEI4(gene name)|psi-mi:MEI4(display_short)|uniprotkb:YER044BC(orf name)|uniprotkb:YER044C-A(locus name)	psi-mi:"MI:0018"(two hybrid)	Arora et al. (2004)	imex:IM-26321|pubmed:14992724	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16715228|imex:IM-26321-43	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YMR133W(gene)|ensemblfungi:YMR133W_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0042138"(meiotic DNA double-strand break formation)|interpro:IPR004354(Meiotic recombination protein rec114)|refseq:NP_013852.1|sgd:S000004740|dip:DIP-4006N	sgd:S000001954|refseq:NP_010963.1|ensemblfungi:YER044C-A(gene)|ensemblfungi:YER044C-A_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0006310"(DNA recombination)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0042138"(meiotic DNA double-strand break formation)|interpro:IPR025888	-	-	-	figure legend:Supplementary table 1-2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/11/17	2017/12/21	rogid:Ct+5dpxGmczgKzWhEhiHiRuxPG4559292	rogid:A9neKqDQ4o5xP4QUOSRJQvJetnY559292	rigid:RT73VRxm81OWfXqTuP++oaHYEp4	false	gal4 activation domain:c-c	lexa dna binding domain:c-c	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P21651	uniprotkb:P29467	intact:EBI-10742|ensemblfungi:YJR021C|uniprotkb:D6VWJ5	intact:EBI-2566907|uniprotkb:P87265|uniprotkb:D3DLU5|ensemblfungi:YER044C-A	psi-mi:re107_yeast(display_long)|uniprotkb:MER2(gene name synonym)|uniprotkb:J1462(orf name)|uniprotkb:YJR021C(locus name)|uniprotkb:REC107(gene name)|psi-mi:REC107(display_short)|uniprotkb:Meiotic recombination protein 2(gene name synonym)	psi-mi:mei4_yeast(display_long)|uniprotkb:MEI4(gene name)|psi-mi:MEI4(display_short)|uniprotkb:YER044BC(orf name)|uniprotkb:YER044C-A(locus name)	psi-mi:"MI:0018"(two hybrid)	Arora et al. (2004)	imex:IM-26321|pubmed:14992724	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16715332|imex:IM-26321-61	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YJR021C(gene)|ensemblfungi:YJR021C_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0042802"(identical protein binding)|interpro:IPR015159(Mer2)|sgd:S000003782|refseq:NP_012555.1|dip:DIP-5265N	sgd:S000001954|refseq:NP_010963.1|ensemblfungi:YER044C-A(gene)|ensemblfungi:YER044C-A_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0006310"(DNA recombination)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0042138"(meiotic DNA double-strand break formation)|interpro:IPR025888	-	crc64:46F426AC0DFDFAD0	-	figure legend:Supplementary table 1-3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/11/17	2017/12/21	rogid:v9kR3rBIptwb/cZE7B5IMAkYWKc559292	rogid:A9neKqDQ4o5xP4QUOSRJQvJetnY559292	rigid:Ii2VK1iJH9buRC7a83Fg8a47yv0	false	gal4 activation domain:c-c	lexa dna binding domain:c-c	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P21651	uniprotkb:P29467	intact:EBI-10742|ensemblfungi:YJR021C|uniprotkb:D6VWJ5	intact:EBI-2566907|uniprotkb:P87265|uniprotkb:D3DLU5|ensemblfungi:YER044C-A	psi-mi:re107_yeast(display_long)|uniprotkb:MER2(gene name synonym)|uniprotkb:J1462(orf name)|uniprotkb:YJR021C(locus name)|uniprotkb:REC107(gene name)|psi-mi:REC107(display_short)|uniprotkb:Meiotic recombination protein 2(gene name synonym)	psi-mi:mei4_yeast(display_long)|uniprotkb:MEI4(gene name)|psi-mi:MEI4(display_short)|uniprotkb:YER044BC(orf name)|uniprotkb:YER044C-A(locus name)	psi-mi:"MI:0018"(two hybrid)	Arora et al. (2004)	imex:IM-26321|pubmed:14992724	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16715340|imex:IM-26321-45	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YJR021C(gene)|ensemblfungi:YJR021C_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0042802"(identical protein binding)|interpro:IPR015159(Mer2)|sgd:S000003782|refseq:NP_012555.1|dip:DIP-5265N	sgd:S000001954|refseq:NP_010963.1|ensemblfungi:YER044C-A(gene)|ensemblfungi:YER044C-A_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0006310"(DNA recombination)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0042138"(meiotic DNA double-strand break formation)|interpro:IPR025888	-	crc64:46F426AC0DFDFAD0	-	figure legend:Supplementary table 1-4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/11/17	2017/12/21	rogid:v9kR3rBIptwb/cZE7B5IMAkYWKc559292	rogid:A9neKqDQ4o5xP4QUOSRJQvJetnY559292	rigid:Ii2VK1iJH9buRC7a83Fg8a47yv0	false	gal4 activation domain:n-n	lexa dna binding domain:c-c	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P12753	uniprotkb:P32829	intact:EBI-14700|uniprotkb:D6W0U3|ensemblfungi:YNL250W	intact:EBI-11255|uniprotkb:P87289|uniprotkb:Q07173|uniprotkb:D6W049|ensemblfungi:YMR224C	psi-mi:rad50_yeast(display_long)|uniprotkb:RAD50(gene name)|psi-mi:RAD50(display_short)|uniprotkb:YNL250W(locus name)|uniprotkb:N0872(orf name)|uniprotkb:153 kDa protein(gene name synonym)	psi-mi:mre11_yeast(display_long)|uniprotkb:YM9959.06C(orf name)|uniprotkb:YMR224C(locus name)|uniprotkb:MRE11(gene name)|psi-mi:MRE11(display_short)	psi-mi:"MI:0018"(two hybrid)	Arora et al. (2004)	imex:IM-26321|pubmed:14992724	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16715394|imex:IM-26321-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014149.1|sgd:S000005194|ensemblfungi:YNL250W(gene)|ensemblfungi:YNL250W_mRNA(transcript)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0004017"(adenylate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006284"(base-excision repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0016787"(hydrolase activity)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030870"(Mre11 complex)|go:"GO:0032078"(negative regulation of endodeoxyribonuclease activity)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0035753"(maintenance of DNA trinucleotide repeats)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0043047"(single-stranded telomeric DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051880"(G-quadruplex DNA binding)|go:"GO:0070192"(chromosome organization involved in meiotic cell cycle)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|go:"GO:0097552"(mitochondrial double-strand break repair via homologous recombination)|interpro:IPR004584(Recombination/repair protein Rad50)|interpro:IPR013134(Zinc hook, Rad50)|interpro:IPR027417|interpro:IPR038729|reactome:R-SCE-5693548|go:"GO:0007129"(homologous chromosome pairing at meiosis)|dip:DIP-2419N|mint:P12753	go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0008296"(3'-5'-exodeoxyribonuclease activity)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0010780"(meiotic DNA double-strand break formation involved in reciprocal meiotic recombination)|go:"GO:0010791"(DNA double-strand break processing involved in repair via synthesis-dependent strand annealing)|go:"GO:0030145"(manganese ion binding)|go:"GO:0030437"(ascospore formation)|go:"GO:0030870"(Mre11 complex)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0035753"(maintenance of DNA trinucleotide repeats)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0043047"(single-stranded telomeric DNA binding)|go:"GO:0046940"(nucleoside monophosphate phosphorylation)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0051037"(regulation of transcription involved in meiotic cell cycle)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0097552"(mitochondrial double-strand break repair via homologous recombination)|interpro:IPR003701(DNA repair exonuclease)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR007281(Mre11, DNA-binding)|interpro:IPR029052|interpro:IPR038487|interpro:IPR041796|reactome:R-SCE-1834949|reactome:R-SCE-5693548|go:"GO:0051880"(G-quadruplex DNA binding)|ensemblfungi:YMR224C(gene)|ensemblfungi:YMR224C_mRNA(transcript)|go:"GO:0000014"(single-stranded DNA endodeoxyribonuclease activity)|go:"GO:0000706"(meiotic DNA double-strand break processing)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0004520"(endodeoxyribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006281"(DNA repair)|go:"GO:0006284"(base-excision repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|refseq:NP_013951.1|sgd:S000004837|mint:P32829|dip:DIP-1313N	-	crc64:58A0AA173AC5677E	crc64:D58433E32E852B73	figure legend:Supplementary table 1-6|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/11/17	2017/12/21	rogid:5Fc4FL8mWNa6ZVO7CVaEwv5ccuk559292	rogid:q3Y06P4MqnJ1vjF7TFYmEzYB9zI559292	rigid:vJK543uqRq1hmrItqlQd9FtIePA	false	gal4 activation domain:n-n	lexa dna binding domain:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P12753	uniprotkb:P32829	intact:EBI-14700|uniprotkb:D6W0U3|ensemblfungi:YNL250W	intact:EBI-11255|uniprotkb:P87289|uniprotkb:Q07173|uniprotkb:D6W049|ensemblfungi:YMR224C	psi-mi:rad50_yeast(display_long)|uniprotkb:RAD50(gene name)|psi-mi:RAD50(display_short)|uniprotkb:YNL250W(locus name)|uniprotkb:N0872(orf name)|uniprotkb:153 kDa protein(gene name synonym)	psi-mi:mre11_yeast(display_long)|uniprotkb:YM9959.06C(orf name)|uniprotkb:YMR224C(locus name)|uniprotkb:MRE11(gene name)|psi-mi:MRE11(display_short)	psi-mi:"MI:0018"(two hybrid)	Arora et al. (2004)	imex:IM-26321|pubmed:14992724	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16715432|imex:IM-26321-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014149.1|sgd:S000005194|ensemblfungi:YNL250W(gene)|ensemblfungi:YNL250W_mRNA(transcript)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0004017"(adenylate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006284"(base-excision repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0016787"(hydrolase activity)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030870"(Mre11 complex)|go:"GO:0032078"(negative regulation of endodeoxyribonuclease activity)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0035753"(maintenance of DNA trinucleotide repeats)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0043047"(single-stranded telomeric DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051880"(G-quadruplex DNA binding)|go:"GO:0070192"(chromosome organization involved in meiotic cell cycle)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|go:"GO:0097552"(mitochondrial double-strand break repair via homologous recombination)|interpro:IPR004584(Recombination/repair protein Rad50)|interpro:IPR013134(Zinc hook, Rad50)|interpro:IPR027417|interpro:IPR038729|reactome:R-SCE-5693548|go:"GO:0007129"(homologous chromosome pairing at meiosis)|dip:DIP-2419N|mint:P12753	go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0008296"(3'-5'-exodeoxyribonuclease activity)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0010780"(meiotic DNA double-strand break formation involved in reciprocal meiotic recombination)|go:"GO:0010791"(DNA double-strand break processing involved in repair via synthesis-dependent strand annealing)|go:"GO:0030145"(manganese ion binding)|go:"GO:0030437"(ascospore formation)|go:"GO:0030870"(Mre11 complex)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0035753"(maintenance of DNA trinucleotide repeats)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0043047"(single-stranded telomeric DNA binding)|go:"GO:0046940"(nucleoside monophosphate phosphorylation)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0051037"(regulation of transcription involved in meiotic cell cycle)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0097552"(mitochondrial double-strand break repair via homologous recombination)|interpro:IPR003701(DNA repair exonuclease)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR007281(Mre11, DNA-binding)|interpro:IPR029052|interpro:IPR038487|interpro:IPR041796|reactome:R-SCE-1834949|reactome:R-SCE-5693548|go:"GO:0051880"(G-quadruplex DNA binding)|ensemblfungi:YMR224C(gene)|ensemblfungi:YMR224C_mRNA(transcript)|go:"GO:0000014"(single-stranded DNA endodeoxyribonuclease activity)|go:"GO:0000706"(meiotic DNA double-strand break processing)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0004520"(endodeoxyribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006281"(DNA repair)|go:"GO:0006284"(base-excision repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|refseq:NP_013951.1|sgd:S000004837|mint:P32829|dip:DIP-1313N	-	crc64:58A0AA173AC5677E	crc64:D58433E32E852B73	figure legend:Supplementary table 1-7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/11/17	2017/12/21	rogid:5Fc4FL8mWNa6ZVO7CVaEwv5ccuk559292	rogid:q3Y06P4MqnJ1vjF7TFYmEzYB9zI559292	rigid:vJK543uqRq1hmrItqlQd9FtIePA	false	gal4 activation domain:n-n	lexa dna binding domain:c-c	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P33301	uniprotkb:P32829	intact:EBI-20599|uniprotkb:D6VT00|ensemblfungi:YDR369C	intact:EBI-11255|uniprotkb:P87289|uniprotkb:Q07173|uniprotkb:D6W049|ensemblfungi:YMR224C	psi-mi:xrs2_yeast(display_long)|uniprotkb:XRS2(gene name)|psi-mi:XRS2(display_short)|uniprotkb:D9481.13(orf name)|uniprotkb:YDR369C(locus name)	psi-mi:mre11_yeast(display_long)|uniprotkb:YM9959.06C(orf name)|uniprotkb:YMR224C(locus name)|uniprotkb:MRE11(gene name)|psi-mi:MRE11(display_short)	psi-mi:"MI:0018"(two hybrid)	Arora et al. (2004)	imex:IM-26321|pubmed:14992724	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16715440|imex:IM-26321-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002777|refseq:NP_010657.3|ensemblfungi:YDR369C(gene)|ensemblfungi:YDR369C_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0003677"(DNA binding)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006284"(base-excision repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030870"(Mre11 complex)|go:"GO:0035753"(maintenance of DNA trinucleotide repeats)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0043047"(single-stranded telomeric DNA binding)|go:"GO:0051880"(G-quadruplex DNA binding)|go:"GO:0097552"(mitochondrial double-strand break repair via homologous recombination)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|dip:DIP-2420N|mint:P33301	go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0008296"(3'-5'-exodeoxyribonuclease activity)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0010780"(meiotic DNA double-strand break formation involved in reciprocal meiotic recombination)|go:"GO:0010791"(DNA double-strand break processing involved in repair via synthesis-dependent strand annealing)|go:"GO:0030145"(manganese ion binding)|go:"GO:0030437"(ascospore formation)|go:"GO:0030870"(Mre11 complex)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0035753"(maintenance of DNA trinucleotide repeats)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0043047"(single-stranded telomeric DNA binding)|go:"GO:0046940"(nucleoside monophosphate phosphorylation)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0051037"(regulation of transcription involved in meiotic cell cycle)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0097552"(mitochondrial double-strand break repair via homologous recombination)|interpro:IPR003701(DNA repair exonuclease)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR007281(Mre11, DNA-binding)|interpro:IPR029052|interpro:IPR038487|interpro:IPR041796|reactome:R-SCE-1834949|reactome:R-SCE-5693548|go:"GO:0051880"(G-quadruplex DNA binding)|ensemblfungi:YMR224C(gene)|ensemblfungi:YMR224C_mRNA(transcript)|go:"GO:0000014"(single-stranded DNA endodeoxyribonuclease activity)|go:"GO:0000706"(meiotic DNA double-strand break processing)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0004520"(endodeoxyribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006281"(DNA repair)|go:"GO:0006284"(base-excision repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|refseq:NP_013951.1|sgd:S000004837|mint:P32829|dip:DIP-1313N	-	crc64:833DAD6D20F6693E	crc64:D58433E32E852B73	figure legend:Supplementary table 1-8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/11/17	2017/12/21	rogid:o505mxGL67ZY1mBUls7e15A4JTY559292	rogid:q3Y06P4MqnJ1vjF7TFYmEzYB9zI559292	rigid:W5fZhoFxd2KhSRYKUjeDENmKYCk	false	gal4 activation domain:n-n	lexa dna binding domain:c-c	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P21651	uniprotkb:P21651	intact:EBI-10742|ensemblfungi:YJR021C|uniprotkb:D6VWJ5	intact:EBI-10742|ensemblfungi:YJR021C|uniprotkb:D6VWJ5	psi-mi:re107_yeast(display_long)|uniprotkb:MER2(gene name synonym)|uniprotkb:J1462(orf name)|uniprotkb:YJR021C(locus name)|uniprotkb:REC107(gene name)|psi-mi:REC107(display_short)|uniprotkb:Meiotic recombination protein 2(gene name synonym)	psi-mi:re107_yeast(display_long)|uniprotkb:MER2(gene name synonym)|uniprotkb:J1462(orf name)|uniprotkb:YJR021C(locus name)|uniprotkb:REC107(gene name)|psi-mi:REC107(display_short)|uniprotkb:Meiotic recombination protein 2(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Arora et al. (2004)	imex:IM-26321|pubmed:14992724	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16715449|imex:IM-26321-21	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YJR021C(gene)|ensemblfungi:YJR021C_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0042802"(identical protein binding)|interpro:IPR015159(Mer2)|sgd:S000003782|refseq:NP_012555.1|dip:DIP-5265N	ensemblfungi:YJR021C(gene)|ensemblfungi:YJR021C_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0042802"(identical protein binding)|interpro:IPR015159(Mer2)|sgd:S000003782|refseq:NP_012555.1|dip:DIP-5265N	-	crc64:46F426AC0DFDFAD0	crc64:46F426AC0DFDFAD0	figure legend:Supplementary table 1-9|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/11/17	2017/12/21	rogid:v9kR3rBIptwb/cZE7B5IMAkYWKc559292	rogid:v9kR3rBIptwb/cZE7B5IMAkYWKc559292	rigid:g9F096gZXhiXDsPNkGW3UmU9xEU	false	gal4 activation domain:c-c	lexa dna binding domain:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P21651	uniprotkb:P21651	intact:EBI-10742|ensemblfungi:YJR021C|uniprotkb:D6VWJ5	intact:EBI-10742|ensemblfungi:YJR021C|uniprotkb:D6VWJ5	psi-mi:re107_yeast(display_long)|uniprotkb:MER2(gene name synonym)|uniprotkb:J1462(orf name)|uniprotkb:YJR021C(locus name)|uniprotkb:REC107(gene name)|psi-mi:REC107(display_short)|uniprotkb:Meiotic recombination protein 2(gene name synonym)	psi-mi:re107_yeast(display_long)|uniprotkb:MER2(gene name synonym)|uniprotkb:J1462(orf name)|uniprotkb:YJR021C(locus name)|uniprotkb:REC107(gene name)|psi-mi:REC107(display_short)|uniprotkb:Meiotic recombination protein 2(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Arora et al. (2004)	imex:IM-26321|pubmed:14992724	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16715457|imex:IM-26321-47	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YJR021C(gene)|ensemblfungi:YJR021C_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0042802"(identical protein binding)|interpro:IPR015159(Mer2)|sgd:S000003782|refseq:NP_012555.1|dip:DIP-5265N	ensemblfungi:YJR021C(gene)|ensemblfungi:YJR021C_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0042802"(identical protein binding)|interpro:IPR015159(Mer2)|sgd:S000003782|refseq:NP_012555.1|dip:DIP-5265N	-	crc64:46F426AC0DFDFAD0	crc64:46F426AC0DFDFAD0	figure legend:Supplementary table 1-10|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/11/17	2017/12/21	rogid:v9kR3rBIptwb/cZE7B5IMAkYWKc559292	rogid:v9kR3rBIptwb/cZE7B5IMAkYWKc559292	rigid:g9F096gZXhiXDsPNkGW3UmU9xEU	false	gal4 activation domain:n-n	lexa dna binding domain:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P21651	uniprotkb:P21651	intact:EBI-10742|ensemblfungi:YJR021C|uniprotkb:D6VWJ5	intact:EBI-10742|ensemblfungi:YJR021C|uniprotkb:D6VWJ5	psi-mi:re107_yeast(display_long)|uniprotkb:MER2(gene name synonym)|uniprotkb:J1462(orf name)|uniprotkb:YJR021C(locus name)|uniprotkb:REC107(gene name)|psi-mi:REC107(display_short)|uniprotkb:Meiotic recombination protein 2(gene name synonym)	psi-mi:re107_yeast(display_long)|uniprotkb:MER2(gene name synonym)|uniprotkb:J1462(orf name)|uniprotkb:YJR021C(locus name)|uniprotkb:REC107(gene name)|psi-mi:REC107(display_short)|uniprotkb:Meiotic recombination protein 2(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Arora et al. (2004)	imex:IM-26321|pubmed:14992724	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16715465|imex:IM-26321-49	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YJR021C(gene)|ensemblfungi:YJR021C_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0042802"(identical protein binding)|interpro:IPR015159(Mer2)|sgd:S000003782|refseq:NP_012555.1|dip:DIP-5265N	ensemblfungi:YJR021C(gene)|ensemblfungi:YJR021C_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0042802"(identical protein binding)|interpro:IPR015159(Mer2)|sgd:S000003782|refseq:NP_012555.1|dip:DIP-5265N	-	crc64:46F426AC0DFDFAD0	crc64:46F426AC0DFDFAD0	figure legend:Supplementary table 1-12|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/11/17	2017/12/21	rogid:v9kR3rBIptwb/cZE7B5IMAkYWKc559292	rogid:v9kR3rBIptwb/cZE7B5IMAkYWKc559292	rigid:g9F096gZXhiXDsPNkGW3UmU9xEU	false	gal4 activation domain:n-n	lexa dna binding domain:c-c	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P21651	uniprotkb:P21651	intact:EBI-10742|ensemblfungi:YJR021C|uniprotkb:D6VWJ5	intact:EBI-10742|ensemblfungi:YJR021C|uniprotkb:D6VWJ5	psi-mi:re107_yeast(display_long)|uniprotkb:MER2(gene name synonym)|uniprotkb:J1462(orf name)|uniprotkb:YJR021C(locus name)|uniprotkb:REC107(gene name)|psi-mi:REC107(display_short)|uniprotkb:Meiotic recombination protein 2(gene name synonym)	psi-mi:re107_yeast(display_long)|uniprotkb:MER2(gene name synonym)|uniprotkb:J1462(orf name)|uniprotkb:YJR021C(locus name)|uniprotkb:REC107(gene name)|psi-mi:REC107(display_short)|uniprotkb:Meiotic recombination protein 2(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Arora et al. (2004)	imex:IM-26321|pubmed:14992724	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16715473|imex:IM-26321-63	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YJR021C(gene)|ensemblfungi:YJR021C_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0042802"(identical protein binding)|interpro:IPR015159(Mer2)|sgd:S000003782|refseq:NP_012555.1|dip:DIP-5265N	ensemblfungi:YJR021C(gene)|ensemblfungi:YJR021C_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0042802"(identical protein binding)|interpro:IPR015159(Mer2)|sgd:S000003782|refseq:NP_012555.1|dip:DIP-5265N	-	crc64:46F426AC0DFDFAD0	crc64:46F426AC0DFDFAD0	figure legend:Supplementary table 1-11|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/11/17	2017/12/21	rogid:v9kR3rBIptwb/cZE7B5IMAkYWKc559292	rogid:v9kR3rBIptwb/cZE7B5IMAkYWKc559292	rigid:g9F096gZXhiXDsPNkGW3UmU9xEU	false	gal4 activation domain:c-c	lexa dna binding domain:c-c	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32841	uniprotkb:P33323	intact:EBI-14447|uniprotkb:D6VZV6|ensemblfungi:YMR133W	intact:EBI-16412992|ensemblfungi:YHR157W|uniprotkb:D3DLA6	psi-mi:re114_yeast(display_long)|uniprotkb:YM9375.02(orf name)|uniprotkb:YMR133W(locus name)|uniprotkb:REC114(gene name)|psi-mi:REC114(display_short)	psi-mi:re104_yeast(display_long)|uniprotkb:REC104(gene name)|psi-mi:REC104(display_short)|uniprotkb:YHR157W(locus name)	psi-mi:"MI:0018"(two hybrid)	Arora et al. (2004)	imex:IM-26321|pubmed:14992724	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16715481|imex:IM-26321-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YMR133W(gene)|ensemblfungi:YMR133W_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0042138"(meiotic DNA double-strand break formation)|interpro:IPR004354(Meiotic recombination protein rec114)|refseq:NP_013852.1|sgd:S000004740|dip:DIP-4006N	ensemblfungi:YHR157W(gene)|ensemblfungi:YHR157W_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0042138"(meiotic DNA double-strand break formation)|interpro:IPR035349|dip:DIP-7960N|refseq:NP_012027.1|sgd:S000001200	-	-	-	figure legend:Supplementary table 1-13|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/11/17	2017/12/21	rogid:Ct+5dpxGmczgKzWhEhiHiRuxPG4559292	rogid:izd4XKs93wK7fXBQxDnwyI172/w559292	rigid:HFhOZAlWUqq+fR5DpKynvSn0hwg	false	gal4 activation domain:c-c	lexa dna binding domain:c-c	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32841	uniprotkb:P32841	intact:EBI-14447|uniprotkb:D6VZV6|ensemblfungi:YMR133W	intact:EBI-14447|uniprotkb:D6VZV6|ensemblfungi:YMR133W	psi-mi:re114_yeast(display_long)|uniprotkb:YM9375.02(orf name)|uniprotkb:YMR133W(locus name)|uniprotkb:REC114(gene name)|psi-mi:REC114(display_short)	psi-mi:re114_yeast(display_long)|uniprotkb:YM9375.02(orf name)|uniprotkb:YMR133W(locus name)|uniprotkb:REC114(gene name)|psi-mi:REC114(display_short)	psi-mi:"MI:0018"(two hybrid)	Arora et al. (2004)	imex:IM-26321|pubmed:14992724	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16715489|imex:IM-26321-51	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YMR133W(gene)|ensemblfungi:YMR133W_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0042138"(meiotic DNA double-strand break formation)|interpro:IPR004354(Meiotic recombination protein rec114)|refseq:NP_013852.1|sgd:S000004740|dip:DIP-4006N	ensemblfungi:YMR133W(gene)|ensemblfungi:YMR133W_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0042138"(meiotic DNA double-strand break formation)|interpro:IPR004354(Meiotic recombination protein rec114)|refseq:NP_013852.1|sgd:S000004740|dip:DIP-4006N	-	-	-	figure legend:Supplementary table 1-14|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/11/17	2017/12/21	rogid:Ct+5dpxGmczgKzWhEhiHiRuxPG4559292	rogid:Ct+5dpxGmczgKzWhEhiHiRuxPG4559292	rigid:yr93wfg8csvohr+A8zOj9TU8woY	false	gal4 activation domain:c-c	lexa dna binding domain:c-c	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P23179	uniprotkb:Q02793	intact:EBI-17705|uniprotkb:D3DKP3|ensemblfungi:YHL022C	intact:EBI-17260|uniprotkb:D6VTU2|ensemblfungi:YGL213C	psi-mi:spo11_yeast(display_long)|uniprotkb:SPO11(gene name)|psi-mi:SPO11(display_short)|uniprotkb:Sporulation-specific protein 11(gene name synonym)|uniprotkb:YHL022C(locus name)	psi-mi:ski8_yeast(display_long)|uniprotkb:YGL213C(locus name)|uniprotkb:SKI8(gene name)|psi-mi:SKI8(display_short)|uniprotkb:REC103(gene name synonym)|uniprotkb:Superkiller protein 8(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Arora et al. (2004)	imex:IM-26321|pubmed:14992724	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16715497|imex:IM-26321-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011841.1|sgd:S000001014|ensemblfungi:YHL022C_mRNA(transcript)|go:"GO:0000228"(nuclear chromosome)|ensemblfungi:YHL022C(gene)|go:"GO:0000706"(meiotic DNA double-strand break processing)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003918"("DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0016889"(endodeoxyribonuclease activity, producing 3'-phosphomonoesters)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0045027"(DNA end binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR002815(Spo11/DNA topoisomerase VI, subunit A)|interpro:IPR013049(Spo11/DNA topoisomerase VI, subunit A, N-terminal)|interpro:IPR034136|interpro:IPR036078|interpro:IPR036388|dip:DIP-1652N	refseq:NP_011302.1|sgd:S000003181|ensemblfungi:YGL213C(gene)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034622"|go:"GO:0051607"(defense response to virus)|go:"GO:0055087"(Ski complex)|go:"GO:0065004"(protein-DNA complex assembly)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|rcsb pdb:1S4U|rcsb pdb:1SQ9|rcsb pdb:4BUJ|rcsb pdb:5MC6|reactome:R-SCE-429958|reactome:R-SCE-674695|reactome:R-SCE-75955|ensemblfungi:YGL213C_mRNA(transcript)|dip:DIP-1653N|mint:Q02793	-	-	crc64:C5E7B9D2268F9727	figure legend:Supplementary table 1-15|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/11/17	2017/12/21	rogid:EYHgcIj0CpPlo8u5DQTW1uK30M4559292	rogid:6K6FJYcctdlT1321Nv6pOnQPwq8559292	rigid:o48vx/gYxs5vr44+ahTeiLwG3wY	false	gal4 activation domain:n-n	lexa dna binding domain:c-c	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P21651	uniprotkb:P33301	intact:EBI-10742|ensemblfungi:YJR021C|uniprotkb:D6VWJ5	intact:EBI-20599|uniprotkb:D6VT00|ensemblfungi:YDR369C	psi-mi:re107_yeast(display_long)|uniprotkb:MER2(gene name synonym)|uniprotkb:J1462(orf name)|uniprotkb:YJR021C(locus name)|uniprotkb:REC107(gene name)|psi-mi:REC107(display_short)|uniprotkb:Meiotic recombination protein 2(gene name synonym)	psi-mi:xrs2_yeast(display_long)|uniprotkb:XRS2(gene name)|psi-mi:XRS2(display_short)|uniprotkb:D9481.13(orf name)|uniprotkb:YDR369C(locus name)	psi-mi:"MI:0018"(two hybrid)	Arora et al. (2004)	imex:IM-26321|pubmed:14992724	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16715507|imex:IM-26321-23	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YJR021C(gene)|ensemblfungi:YJR021C_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0042802"(identical protein binding)|interpro:IPR015159(Mer2)|sgd:S000003782|refseq:NP_012555.1|dip:DIP-5265N	sgd:S000002777|refseq:NP_010657.3|ensemblfungi:YDR369C(gene)|ensemblfungi:YDR369C_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0003677"(DNA binding)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006284"(base-excision repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030870"(Mre11 complex)|go:"GO:0035753"(maintenance of DNA trinucleotide repeats)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0043047"(single-stranded telomeric DNA binding)|go:"GO:0051880"(G-quadruplex DNA binding)|go:"GO:0097552"(mitochondrial double-strand break repair via homologous recombination)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|dip:DIP-2420N|mint:P33301	-	crc64:46F426AC0DFDFAD0	crc64:833DAD6D20F6693E	figure legend:Supplementary table 1-16|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/11/17	2017/12/21	rogid:v9kR3rBIptwb/cZE7B5IMAkYWKc559292	rogid:o505mxGL67ZY1mBUls7e15A4JTY559292	rigid:aGQTlAZfNc+OHtwAp0DYUkYnfTw	false	gal4 activation domain:n-n	lexa dna binding domain:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P23179	uniprotkb:Q02793	intact:EBI-17705|uniprotkb:D3DKP3|ensemblfungi:YHL022C	intact:EBI-17260|uniprotkb:D6VTU2|ensemblfungi:YGL213C	psi-mi:spo11_yeast(display_long)|uniprotkb:SPO11(gene name)|psi-mi:SPO11(display_short)|uniprotkb:Sporulation-specific protein 11(gene name synonym)|uniprotkb:YHL022C(locus name)	psi-mi:ski8_yeast(display_long)|uniprotkb:YGL213C(locus name)|uniprotkb:SKI8(gene name)|psi-mi:SKI8(display_short)|uniprotkb:REC103(gene name synonym)|uniprotkb:Superkiller protein 8(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Arora et al. (2004)	imex:IM-26321|pubmed:14992724	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16715598|imex:IM-26321-15	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011841.1|sgd:S000001014|ensemblfungi:YHL022C_mRNA(transcript)|go:"GO:0000228"(nuclear chromosome)|ensemblfungi:YHL022C(gene)|go:"GO:0000706"(meiotic DNA double-strand break processing)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003918"("DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0016889"(endodeoxyribonuclease activity, producing 3'-phosphomonoesters)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0045027"(DNA end binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR002815(Spo11/DNA topoisomerase VI, subunit A)|interpro:IPR013049(Spo11/DNA topoisomerase VI, subunit A, N-terminal)|interpro:IPR034136|interpro:IPR036078|interpro:IPR036388|dip:DIP-1652N	refseq:NP_011302.1|sgd:S000003181|ensemblfungi:YGL213C(gene)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034622"|go:"GO:0051607"(defense response to virus)|go:"GO:0055087"(Ski complex)|go:"GO:0065004"(protein-DNA complex assembly)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|rcsb pdb:1S4U|rcsb pdb:1SQ9|rcsb pdb:4BUJ|rcsb pdb:5MC6|reactome:R-SCE-429958|reactome:R-SCE-674695|reactome:R-SCE-75955|ensemblfungi:YGL213C_mRNA(transcript)|dip:DIP-1653N|mint:Q02793	-	-	crc64:C5E7B9D2268F9727	figure legend:Figure 6B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/11/17	2017/12/21	rogid:EYHgcIj0CpPlo8u5DQTW1uK30M4559292	rogid:6K6FJYcctdlT1321Nv6pOnQPwq8559292	rigid:o48vx/gYxs5vr44+ahTeiLwG3wY	false	gal4 activation domain:n-n|mutation disrupting interaction strength:376-376|mutation disrupting interaction strength:377-378	lexa dna binding domain:c-c	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q02793	uniprotkb:P23179	intact:EBI-17260|uniprotkb:D6VTU2|ensemblfungi:YGL213C	intact:EBI-17705|uniprotkb:D3DKP3|ensemblfungi:YHL022C	psi-mi:ski8_yeast(display_long)|uniprotkb:YGL213C(locus name)|uniprotkb:SKI8(gene name)|psi-mi:SKI8(display_short)|uniprotkb:REC103(gene name synonym)|uniprotkb:Superkiller protein 8(gene name synonym)	psi-mi:spo11_yeast(display_long)|uniprotkb:SPO11(gene name)|psi-mi:SPO11(display_short)|uniprotkb:Sporulation-specific protein 11(gene name synonym)|uniprotkb:YHL022C(locus name)	psi-mi:"MI:0018"(two hybrid)	Arora et al. (2004)	imex:IM-26321|pubmed:14992724	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16715612|imex:IM-26321-67	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011302.1|sgd:S000003181|ensemblfungi:YGL213C(gene)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034622"|go:"GO:0051607"(defense response to virus)|go:"GO:0055087"(Ski complex)|go:"GO:0065004"(protein-DNA complex assembly)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|rcsb pdb:1S4U|rcsb pdb:1SQ9|rcsb pdb:4BUJ|rcsb pdb:5MC6|reactome:R-SCE-429958|reactome:R-SCE-674695|reactome:R-SCE-75955|ensemblfungi:YGL213C_mRNA(transcript)|dip:DIP-1653N|mint:Q02793	refseq:NP_011841.1|sgd:S000001014|ensemblfungi:YHL022C_mRNA(transcript)|go:"GO:0000228"(nuclear chromosome)|ensemblfungi:YHL022C(gene)|go:"GO:0000706"(meiotic DNA double-strand break processing)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003918"("DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0016889"(endodeoxyribonuclease activity, producing 3'-phosphomonoesters)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0045027"(DNA end binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR002815(Spo11/DNA topoisomerase VI, subunit A)|interpro:IPR013049(Spo11/DNA topoisomerase VI, subunit A, N-terminal)|interpro:IPR034136|interpro:IPR036078|interpro:IPR036388|dip:DIP-1652N	-	crc64:C5E7B9D2268F9727	-	figure legend:Supplementary table 1-5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/11/17	2017/12/21	rogid:6K6FJYcctdlT1321Nv6pOnQPwq8559292	rogid:EYHgcIj0CpPlo8u5DQTW1uK30M4559292	rigid:o48vx/gYxs5vr44+ahTeiLwG3wY	false	gal4 activation domain:c-c	lexa dna binding domain:c-c	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P21651	uniprotkb:P32829	intact:EBI-10742|ensemblfungi:YJR021C|uniprotkb:D6VWJ5	intact:EBI-11255|uniprotkb:P87289|uniprotkb:Q07173|uniprotkb:D6W049|ensemblfungi:YMR224C	psi-mi:re107_yeast(display_long)|uniprotkb:MER2(gene name synonym)|uniprotkb:J1462(orf name)|uniprotkb:YJR021C(locus name)|uniprotkb:REC107(gene name)|psi-mi:REC107(display_short)|uniprotkb:Meiotic recombination protein 2(gene name synonym)	psi-mi:mre11_yeast(display_long)|uniprotkb:YM9959.06C(orf name)|uniprotkb:YMR224C(locus name)|uniprotkb:MRE11(gene name)|psi-mi:MRE11(display_short)	psi-mi:"MI:0018"(two hybrid)	Arora et al. (2004)	imex:IM-26321|pubmed:14992724	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16715678|imex:IM-26321-55	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YJR021C(gene)|ensemblfungi:YJR021C_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0042802"(identical protein binding)|interpro:IPR015159(Mer2)|sgd:S000003782|refseq:NP_012555.1|dip:DIP-5265N	go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0008296"(3'-5'-exodeoxyribonuclease activity)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0010780"(meiotic DNA double-strand break formation involved in reciprocal meiotic recombination)|go:"GO:0010791"(DNA double-strand break processing involved in repair via synthesis-dependent strand annealing)|go:"GO:0030145"(manganese ion binding)|go:"GO:0030437"(ascospore formation)|go:"GO:0030870"(Mre11 complex)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0035753"(maintenance of DNA trinucleotide repeats)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0043047"(single-stranded telomeric DNA binding)|go:"GO:0046940"(nucleoside monophosphate phosphorylation)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0051037"(regulation of transcription involved in meiotic cell cycle)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0097552"(mitochondrial double-strand break repair via homologous recombination)|interpro:IPR003701(DNA repair exonuclease)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR007281(Mre11, DNA-binding)|interpro:IPR029052|interpro:IPR038487|interpro:IPR041796|reactome:R-SCE-1834949|reactome:R-SCE-5693548|go:"GO:0051880"(G-quadruplex DNA binding)|ensemblfungi:YMR224C(gene)|ensemblfungi:YMR224C_mRNA(transcript)|go:"GO:0000014"(single-stranded DNA endodeoxyribonuclease activity)|go:"GO:0000706"(meiotic DNA double-strand break processing)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0004520"(endodeoxyribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006281"(DNA repair)|go:"GO:0006284"(base-excision repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|refseq:NP_013951.1|sgd:S000004837|mint:P32829|dip:DIP-1313N	-	crc64:46F426AC0DFDFAD0	crc64:D58433E32E852B73	figure legend:Figure 1B-1|comment:weak interaction|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/11/17	2017/12/21	rogid:v9kR3rBIptwb/cZE7B5IMAkYWKc559292	rogid:q3Y06P4MqnJ1vjF7TFYmEzYB9zI559292	rigid:5AtTA80qFX6+8LnpYxzDvFOJ3vg	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P33323	uniprotkb:P32829	intact:EBI-16412992|ensemblfungi:YHR157W|uniprotkb:D3DLA6	intact:EBI-11255|uniprotkb:P87289|uniprotkb:Q07173|uniprotkb:D6W049|ensemblfungi:YMR224C	psi-mi:re104_yeast(display_long)|uniprotkb:REC104(gene name)|psi-mi:REC104(display_short)|uniprotkb:YHR157W(locus name)	psi-mi:mre11_yeast(display_long)|uniprotkb:YM9959.06C(orf name)|uniprotkb:YMR224C(locus name)|uniprotkb:MRE11(gene name)|psi-mi:MRE11(display_short)	psi-mi:"MI:0018"(two hybrid)	Arora et al. (2004)	imex:IM-26321|pubmed:14992724	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16715687|imex:IM-26321-35	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YHR157W(gene)|ensemblfungi:YHR157W_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0042138"(meiotic DNA double-strand break formation)|interpro:IPR035349|dip:DIP-7960N|refseq:NP_012027.1|sgd:S000001200	go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0008296"(3'-5'-exodeoxyribonuclease activity)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0010780"(meiotic DNA double-strand break formation involved in reciprocal meiotic recombination)|go:"GO:0010791"(DNA double-strand break processing involved in repair via synthesis-dependent strand annealing)|go:"GO:0030145"(manganese ion binding)|go:"GO:0030437"(ascospore formation)|go:"GO:0030870"(Mre11 complex)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0035753"(maintenance of DNA trinucleotide repeats)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0043047"(single-stranded telomeric DNA binding)|go:"GO:0046940"(nucleoside monophosphate phosphorylation)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0051037"(regulation of transcription involved in meiotic cell cycle)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0097552"(mitochondrial double-strand break repair via homologous recombination)|interpro:IPR003701(DNA repair exonuclease)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR007281(Mre11, DNA-binding)|interpro:IPR029052|interpro:IPR038487|interpro:IPR041796|reactome:R-SCE-1834949|reactome:R-SCE-5693548|go:"GO:0051880"(G-quadruplex DNA binding)|ensemblfungi:YMR224C(gene)|ensemblfungi:YMR224C_mRNA(transcript)|go:"GO:0000014"(single-stranded DNA endodeoxyribonuclease activity)|go:"GO:0000706"(meiotic DNA double-strand break processing)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0004520"(endodeoxyribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006281"(DNA repair)|go:"GO:0006284"(base-excision repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|refseq:NP_013951.1|sgd:S000004837|mint:P32829|dip:DIP-1313N	-	-	crc64:D58433E32E852B73	figure legend:Figure 1B-2|comment:weak interaction|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/11/17	2017/12/21	rogid:izd4XKs93wK7fXBQxDnwyI172/w559292	rogid:q3Y06P4MqnJ1vjF7TFYmEzYB9zI559292	rigid:p0kLAeNX8kgQCFcJBf8glADQsK0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32841	uniprotkb:Q02721	intact:EBI-14447|uniprotkb:D6VZV6|ensemblfungi:YMR133W	intact:EBI-14432|ensemblfungi:YLR329W|uniprotkb:D6VYX1	psi-mi:re114_yeast(display_long)|uniprotkb:YM9375.02(orf name)|uniprotkb:YMR133W(locus name)|uniprotkb:REC114(gene name)|psi-mi:REC114(display_short)	psi-mi:to6bl_yeast(display_long)|uniprotkb:L8543.17(orf name)|uniprotkb:YLR329W(locus name)|uniprotkb:REC102(gene name)|psi-mi:REC102(display_short)	psi-mi:"MI:0018"(two hybrid)	Arora et al. (2004)	imex:IM-26321|pubmed:14992724	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16715692|imex:IM-26321-71	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YMR133W(gene)|ensemblfungi:YMR133W_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0042138"(meiotic DNA double-strand break formation)|interpro:IPR004354(Meiotic recombination protein rec114)|refseq:NP_013852.1|sgd:S000004740|dip:DIP-4006N	sgd:S000004321|ensemblfungi:YLR329W(gene)|ensemblfungi:YLR329W_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0042138"(meiotic DNA double-strand break formation)|refseq:NP_013433.2|dip:DIP-4675N	-	-	-	figure legend:Figure 1B-3|comment:weak interaction|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/11/17	2017/12/21	rogid:Ct+5dpxGmczgKzWhEhiHiRuxPG4559292	rogid:VmAThA+J0AAeMMGfpZCGNMxEcY8559292	rigid:F48AcI6av0i6hrqimD1y4XWmEjY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P33323	uniprotkb:Q02721	intact:EBI-16412992|ensemblfungi:YHR157W|uniprotkb:D3DLA6	intact:EBI-14432|ensemblfungi:YLR329W|uniprotkb:D6VYX1	psi-mi:re104_yeast(display_long)|uniprotkb:REC104(gene name)|psi-mi:REC104(display_short)|uniprotkb:YHR157W(locus name)	psi-mi:to6bl_yeast(display_long)|uniprotkb:L8543.17(orf name)|uniprotkb:YLR329W(locus name)|uniprotkb:REC102(gene name)|psi-mi:REC102(display_short)	psi-mi:"MI:0018"(two hybrid)	Arora et al. (2004)	imex:IM-26321|pubmed:14992724	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16715697|imex:IM-26321-73	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YHR157W(gene)|ensemblfungi:YHR157W_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0042138"(meiotic DNA double-strand break formation)|interpro:IPR035349|dip:DIP-7960N|refseq:NP_012027.1|sgd:S000001200	sgd:S000004321|ensemblfungi:YLR329W(gene)|ensemblfungi:YLR329W_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0042138"(meiotic DNA double-strand break formation)|refseq:NP_013433.2|dip:DIP-4675N	-	-	-	figure legend:Figure 1B-5|comment:weak interaction|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/11/17	2017/12/21	rogid:izd4XKs93wK7fXBQxDnwyI172/w559292	rogid:VmAThA+J0AAeMMGfpZCGNMxEcY8559292	rigid:EIMHvmxY+HDMmz/hfBXxVfvN6RA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P33323	uniprotkb:P33323	intact:EBI-16412992|ensemblfungi:YHR157W|uniprotkb:D3DLA6	intact:EBI-16412992|ensemblfungi:YHR157W|uniprotkb:D3DLA6	psi-mi:re104_yeast(display_long)|uniprotkb:REC104(gene name)|psi-mi:REC104(display_short)|uniprotkb:YHR157W(locus name)	psi-mi:re104_yeast(display_long)|uniprotkb:REC104(gene name)|psi-mi:REC104(display_short)|uniprotkb:YHR157W(locus name)	psi-mi:"MI:0018"(two hybrid)	Arora et al. (2004)	imex:IM-26321|pubmed:14992724	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16715702|imex:IM-26321-57	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YHR157W(gene)|ensemblfungi:YHR157W_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0042138"(meiotic DNA double-strand break formation)|interpro:IPR035349|dip:DIP-7960N|refseq:NP_012027.1|sgd:S000001200	ensemblfungi:YHR157W(gene)|ensemblfungi:YHR157W_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0042138"(meiotic DNA double-strand break formation)|interpro:IPR035349|dip:DIP-7960N|refseq:NP_012027.1|sgd:S000001200	-	-	-	figure legend:Figure 1B-4|comment:weak interaction|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/11/17	2017/12/21	rogid:izd4XKs93wK7fXBQxDnwyI172/w559292	rogid:izd4XKs93wK7fXBQxDnwyI172/w559292	rigid:TKLl6SxhtykHs1/pcFlWUsfi/h8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P21651	uniprotkb:Q02793	intact:EBI-10742|ensemblfungi:YJR021C|uniprotkb:D6VWJ5	intact:EBI-17260|uniprotkb:D6VTU2|ensemblfungi:YGL213C	psi-mi:re107_yeast(display_long)|uniprotkb:MER2(gene name synonym)|uniprotkb:J1462(orf name)|uniprotkb:YJR021C(locus name)|uniprotkb:REC107(gene name)|psi-mi:REC107(display_short)|uniprotkb:Meiotic recombination protein 2(gene name synonym)	psi-mi:ski8_yeast(display_long)|uniprotkb:YGL213C(locus name)|uniprotkb:SKI8(gene name)|psi-mi:SKI8(display_short)|uniprotkb:REC103(gene name synonym)|uniprotkb:Superkiller protein 8(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Arora et al. (2004)	imex:IM-26321|pubmed:14992724	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16715707|imex:IM-26321-59	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YJR021C(gene)|ensemblfungi:YJR021C_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0042802"(identical protein binding)|interpro:IPR015159(Mer2)|sgd:S000003782|refseq:NP_012555.1|dip:DIP-5265N	refseq:NP_011302.1|sgd:S000003181|ensemblfungi:YGL213C(gene)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034622"|go:"GO:0051607"(defense response to virus)|go:"GO:0055087"(Ski complex)|go:"GO:0065004"(protein-DNA complex assembly)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|rcsb pdb:1S4U|rcsb pdb:1SQ9|rcsb pdb:4BUJ|rcsb pdb:5MC6|reactome:R-SCE-429958|reactome:R-SCE-674695|reactome:R-SCE-75955|ensemblfungi:YGL213C_mRNA(transcript)|dip:DIP-1653N|mint:Q02793	-	crc64:46F426AC0DFDFAD0	crc64:C5E7B9D2268F9727	figure legend:Figure 1B-6|comment:weak interaction|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/11/17	2017/12/21	rogid:v9kR3rBIptwb/cZE7B5IMAkYWKc559292	rogid:6K6FJYcctdlT1321Nv6pOnQPwq8559292	rigid:zV13Lj7OFI/YQhdhl7Qdb+qFyRE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32841	uniprotkb:Q02793	intact:EBI-14447|uniprotkb:D6VZV6|ensemblfungi:YMR133W	intact:EBI-17260|uniprotkb:D6VTU2|ensemblfungi:YGL213C	psi-mi:re114_yeast(display_long)|uniprotkb:YM9375.02(orf name)|uniprotkb:YMR133W(locus name)|uniprotkb:REC114(gene name)|psi-mi:REC114(display_short)	psi-mi:ski8_yeast(display_long)|uniprotkb:YGL213C(locus name)|uniprotkb:SKI8(gene name)|psi-mi:SKI8(display_short)|uniprotkb:REC103(gene name synonym)|uniprotkb:Superkiller protein 8(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Arora et al. (2004)	imex:IM-26321|pubmed:14992724	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16715712|imex:IM-26321-19	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YMR133W(gene)|ensemblfungi:YMR133W_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0042138"(meiotic DNA double-strand break formation)|interpro:IPR004354(Meiotic recombination protein rec114)|refseq:NP_013852.1|sgd:S000004740|dip:DIP-4006N	refseq:NP_011302.1|sgd:S000003181|ensemblfungi:YGL213C(gene)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034622"|go:"GO:0051607"(defense response to virus)|go:"GO:0055087"(Ski complex)|go:"GO:0065004"(protein-DNA complex assembly)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|rcsb pdb:1S4U|rcsb pdb:1SQ9|rcsb pdb:4BUJ|rcsb pdb:5MC6|reactome:R-SCE-429958|reactome:R-SCE-674695|reactome:R-SCE-75955|ensemblfungi:YGL213C_mRNA(transcript)|dip:DIP-1653N|mint:Q02793	-	-	crc64:C5E7B9D2268F9727	figure legend:Figure 1B-7|comment:weak interaction|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/11/17	2017/12/21	rogid:Ct+5dpxGmczgKzWhEhiHiRuxPG4559292	rogid:6K6FJYcctdlT1321Nv6pOnQPwq8559292	rigid:tcoowin3xH4z/MYI1ecX526z+tI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P21651	uniprotkb:P33323	intact:EBI-10742|ensemblfungi:YJR021C|uniprotkb:D6VWJ5	intact:EBI-16412992|ensemblfungi:YHR157W|uniprotkb:D3DLA6	psi-mi:re107_yeast(display_long)|uniprotkb:MER2(gene name synonym)|uniprotkb:J1462(orf name)|uniprotkb:YJR021C(locus name)|uniprotkb:REC107(gene name)|psi-mi:REC107(display_short)|uniprotkb:Meiotic recombination protein 2(gene name synonym)	psi-mi:re104_yeast(display_long)|uniprotkb:REC104(gene name)|psi-mi:REC104(display_short)|uniprotkb:YHR157W(locus name)	psi-mi:"MI:0018"(two hybrid)	Arora et al. (2004)	imex:IM-26321|pubmed:14992724	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16715717|imex:IM-26321-37	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YJR021C(gene)|ensemblfungi:YJR021C_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0042802"(identical protein binding)|interpro:IPR015159(Mer2)|sgd:S000003782|refseq:NP_012555.1|dip:DIP-5265N	ensemblfungi:YHR157W(gene)|ensemblfungi:YHR157W_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0042138"(meiotic DNA double-strand break formation)|interpro:IPR035349|dip:DIP-7960N|refseq:NP_012027.1|sgd:S000001200	-	crc64:46F426AC0DFDFAD0	-	figure legend:Figure 1B-8|comment:weak interaction|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/11/17	2017/12/21	rogid:v9kR3rBIptwb/cZE7B5IMAkYWKc559292	rogid:izd4XKs93wK7fXBQxDnwyI172/w559292	rigid:JUzOQ6w7d1yFESaSEU+IJ2A3nks	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q02721	uniprotkb:P33323	intact:EBI-14432|ensemblfungi:YLR329W|uniprotkb:D6VYX1	intact:EBI-16412992|ensemblfungi:YHR157W|uniprotkb:D3DLA6	psi-mi:to6bl_yeast(display_long)|uniprotkb:L8543.17(orf name)|uniprotkb:YLR329W(locus name)|uniprotkb:REC102(gene name)|psi-mi:REC102(display_short)	psi-mi:re104_yeast(display_long)|uniprotkb:REC104(gene name)|psi-mi:REC104(display_short)|uniprotkb:YHR157W(locus name)	psi-mi:"MI:0018"(two hybrid)	Arora et al. (2004)	imex:IM-26321|pubmed:14992724	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16715722|imex:IM-26321-75	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000004321|ensemblfungi:YLR329W(gene)|ensemblfungi:YLR329W_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0042138"(meiotic DNA double-strand break formation)|refseq:NP_013433.2|dip:DIP-4675N	ensemblfungi:YHR157W(gene)|ensemblfungi:YHR157W_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0042138"(meiotic DNA double-strand break formation)|interpro:IPR035349|dip:DIP-7960N|refseq:NP_012027.1|sgd:S000001200	-	-	-	figure legend:Figure 1B-9|comment:weak interaction|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/11/17	2017/12/21	rogid:VmAThA+J0AAeMMGfpZCGNMxEcY8559292	rogid:izd4XKs93wK7fXBQxDnwyI172/w559292	rigid:EIMHvmxY+HDMmz/hfBXxVfvN6RA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32841	uniprotkb:P21651	intact:EBI-14447|uniprotkb:D6VZV6|ensemblfungi:YMR133W	intact:EBI-10742|ensemblfungi:YJR021C|uniprotkb:D6VWJ5	psi-mi:re114_yeast(display_long)|uniprotkb:YM9375.02(orf name)|uniprotkb:YMR133W(locus name)|uniprotkb:REC114(gene name)|psi-mi:REC114(display_short)	psi-mi:re107_yeast(display_long)|uniprotkb:MER2(gene name synonym)|uniprotkb:J1462(orf name)|uniprotkb:YJR021C(locus name)|uniprotkb:REC107(gene name)|psi-mi:REC107(display_short)|uniprotkb:Meiotic recombination protein 2(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Arora et al. (2004)	imex:IM-26321|pubmed:14992724	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16715545|imex:IM-26321-25	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YMR133W(gene)|ensemblfungi:YMR133W_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0042138"(meiotic DNA double-strand break formation)|interpro:IPR004354(Meiotic recombination protein rec114)|refseq:NP_013852.1|sgd:S000004740|dip:DIP-4006N	ensemblfungi:YJR021C(gene)|ensemblfungi:YJR021C_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0042802"(identical protein binding)|interpro:IPR015159(Mer2)|sgd:S000003782|refseq:NP_012555.1|dip:DIP-5265N	-	-	crc64:46F426AC0DFDFAD0	figure legend:Supplementary table 2-1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/11/17	2017/12/21	rogid:Ct+5dpxGmczgKzWhEhiHiRuxPG4559292	rogid:v9kR3rBIptwb/cZE7B5IMAkYWKc559292	rigid:Cui17e+My6MeQtHvT7DhE6M2/6w	false	gal4 activation domain:c-c	lexa dna binding domain:c-c	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P33323	uniprotkb:P23179	intact:EBI-16412992|ensemblfungi:YHR157W|uniprotkb:D3DLA6	intact:EBI-17705|uniprotkb:D3DKP3|ensemblfungi:YHL022C	psi-mi:re104_yeast(display_long)|uniprotkb:REC104(gene name)|psi-mi:REC104(display_short)|uniprotkb:YHR157W(locus name)	psi-mi:spo11_yeast(display_long)|uniprotkb:SPO11(gene name)|psi-mi:SPO11(display_short)|uniprotkb:Sporulation-specific protein 11(gene name synonym)|uniprotkb:YHL022C(locus name)	psi-mi:"MI:0018"(two hybrid)	Arora et al. (2004)	imex:IM-26321|pubmed:14992724	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16715553|imex:IM-26321-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YHR157W(gene)|ensemblfungi:YHR157W_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0042138"(meiotic DNA double-strand break formation)|interpro:IPR035349|dip:DIP-7960N|refseq:NP_012027.1|sgd:S000001200	refseq:NP_011841.1|sgd:S000001014|ensemblfungi:YHL022C_mRNA(transcript)|go:"GO:0000228"(nuclear chromosome)|ensemblfungi:YHL022C(gene)|go:"GO:0000706"(meiotic DNA double-strand break processing)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003918"("DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0016889"(endodeoxyribonuclease activity, producing 3'-phosphomonoesters)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0045027"(DNA end binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR002815(Spo11/DNA topoisomerase VI, subunit A)|interpro:IPR013049(Spo11/DNA topoisomerase VI, subunit A, N-terminal)|interpro:IPR034136|interpro:IPR036078|interpro:IPR036388|dip:DIP-1652N	-	-	-	figure legend:Supplementary table 2-2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/11/17	2017/12/21	rogid:izd4XKs93wK7fXBQxDnwyI172/w559292	rogid:EYHgcIj0CpPlo8u5DQTW1uK30M4559292	rigid:E83lMfOe9S+gVZYkyXDHd+98k0Y	false	gal4 activation domain:c-c	lexa dna binding domain:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P33323	uniprotkb:P23179	intact:EBI-16412992|ensemblfungi:YHR157W|uniprotkb:D3DLA6	intact:EBI-17705|uniprotkb:D3DKP3|ensemblfungi:YHL022C	psi-mi:re104_yeast(display_long)|uniprotkb:REC104(gene name)|psi-mi:REC104(display_short)|uniprotkb:YHR157W(locus name)	psi-mi:spo11_yeast(display_long)|uniprotkb:SPO11(gene name)|psi-mi:SPO11(display_short)|uniprotkb:Sporulation-specific protein 11(gene name synonym)|uniprotkb:YHL022C(locus name)	psi-mi:"MI:0018"(two hybrid)	Arora et al. (2004)	imex:IM-26321|pubmed:14992724	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16715563|imex:IM-26321-27	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YHR157W(gene)|ensemblfungi:YHR157W_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0042138"(meiotic DNA double-strand break formation)|interpro:IPR035349|dip:DIP-7960N|refseq:NP_012027.1|sgd:S000001200	refseq:NP_011841.1|sgd:S000001014|ensemblfungi:YHL022C_mRNA(transcript)|go:"GO:0000228"(nuclear chromosome)|ensemblfungi:YHL022C(gene)|go:"GO:0000706"(meiotic DNA double-strand break processing)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003918"("DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0016889"(endodeoxyribonuclease activity, producing 3'-phosphomonoesters)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0045027"(DNA end binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR002815(Spo11/DNA topoisomerase VI, subunit A)|interpro:IPR013049(Spo11/DNA topoisomerase VI, subunit A, N-terminal)|interpro:IPR034136|interpro:IPR036078|interpro:IPR036388|dip:DIP-1652N	-	-	-	figure legend:Supplementary table 2-4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/11/17	2017/12/21	rogid:izd4XKs93wK7fXBQxDnwyI172/w559292	rogid:EYHgcIj0CpPlo8u5DQTW1uK30M4559292	rigid:E83lMfOe9S+gVZYkyXDHd+98k0Y	false	gal4 activation domain:n-n	lexa dna binding domain:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q02793	uniprotkb:P23179	intact:EBI-17260|uniprotkb:D6VTU2|ensemblfungi:YGL213C	intact:EBI-17705|uniprotkb:D3DKP3|ensemblfungi:YHL022C	psi-mi:ski8_yeast(display_long)|uniprotkb:YGL213C(locus name)|uniprotkb:SKI8(gene name)|psi-mi:SKI8(display_short)|uniprotkb:REC103(gene name synonym)|uniprotkb:Superkiller protein 8(gene name synonym)	psi-mi:spo11_yeast(display_long)|uniprotkb:SPO11(gene name)|psi-mi:SPO11(display_short)|uniprotkb:Sporulation-specific protein 11(gene name synonym)|uniprotkb:YHL022C(locus name)	psi-mi:"MI:0018"(two hybrid)	Arora et al. (2004)	imex:IM-26321|pubmed:14992724	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16715575|imex:IM-26321-65	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011302.1|sgd:S000003181|ensemblfungi:YGL213C(gene)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034622"|go:"GO:0051607"(defense response to virus)|go:"GO:0055087"(Ski complex)|go:"GO:0065004"(protein-DNA complex assembly)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|rcsb pdb:1S4U|rcsb pdb:1SQ9|rcsb pdb:4BUJ|rcsb pdb:5MC6|reactome:R-SCE-429958|reactome:R-SCE-674695|reactome:R-SCE-75955|ensemblfungi:YGL213C_mRNA(transcript)|dip:DIP-1653N|mint:Q02793	refseq:NP_011841.1|sgd:S000001014|ensemblfungi:YHL022C_mRNA(transcript)|go:"GO:0000228"(nuclear chromosome)|ensemblfungi:YHL022C(gene)|go:"GO:0000706"(meiotic DNA double-strand break processing)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003918"("DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0016889"(endodeoxyribonuclease activity, producing 3'-phosphomonoesters)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0045027"(DNA end binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR002815(Spo11/DNA topoisomerase VI, subunit A)|interpro:IPR013049(Spo11/DNA topoisomerase VI, subunit A, N-terminal)|interpro:IPR034136|interpro:IPR036078|interpro:IPR036388|dip:DIP-1652N	-	crc64:C5E7B9D2268F9727	-	figure legend:Supplementary table 2-3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/11/17	2017/12/21	rogid:6K6FJYcctdlT1321Nv6pOnQPwq8559292	rogid:EYHgcIj0CpPlo8u5DQTW1uK30M4559292	rigid:o48vx/gYxs5vr44+ahTeiLwG3wY	false	gal4 activation domain:c-c	lexa dna binding domain:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P23179	uniprotkb:P33323	intact:EBI-17705|uniprotkb:D3DKP3|ensemblfungi:YHL022C	intact:EBI-16412992|ensemblfungi:YHR157W|uniprotkb:D3DLA6	psi-mi:spo11_yeast(display_long)|uniprotkb:SPO11(gene name)|psi-mi:SPO11(display_short)|uniprotkb:Sporulation-specific protein 11(gene name synonym)|uniprotkb:YHL022C(locus name)	psi-mi:re104_yeast(display_long)|uniprotkb:REC104(gene name)|psi-mi:REC104(display_short)|uniprotkb:YHR157W(locus name)	psi-mi:"MI:0018"(two hybrid)	Arora et al. (2004)	imex:IM-26321|pubmed:14992724	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16715585|imex:IM-26321-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011841.1|sgd:S000001014|ensemblfungi:YHL022C_mRNA(transcript)|go:"GO:0000228"(nuclear chromosome)|ensemblfungi:YHL022C(gene)|go:"GO:0000706"(meiotic DNA double-strand break processing)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003918"("DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0016889"(endodeoxyribonuclease activity, producing 3'-phosphomonoesters)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0045027"(DNA end binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR002815(Spo11/DNA topoisomerase VI, subunit A)|interpro:IPR013049(Spo11/DNA topoisomerase VI, subunit A, N-terminal)|interpro:IPR034136|interpro:IPR036078|interpro:IPR036388|dip:DIP-1652N	ensemblfungi:YHR157W(gene)|ensemblfungi:YHR157W_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0042138"(meiotic DNA double-strand break formation)|interpro:IPR035349|dip:DIP-7960N|refseq:NP_012027.1|sgd:S000001200	-	-	-	figure legend:Supplementary table 2-5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/11/17	2017/12/21	rogid:EYHgcIj0CpPlo8u5DQTW1uK30M4559292	rogid:izd4XKs93wK7fXBQxDnwyI172/w559292	rigid:E83lMfOe9S+gVZYkyXDHd+98k0Y	false	gal4 activation domain:n-n	lexa dna binding domain:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P23179	uniprotkb:P33323	intact:EBI-17705|uniprotkb:D3DKP3|ensemblfungi:YHL022C	intact:EBI-16412992|ensemblfungi:YHR157W|uniprotkb:D3DLA6	psi-mi:spo11_yeast(display_long)|uniprotkb:SPO11(gene name)|psi-mi:SPO11(display_short)|uniprotkb:Sporulation-specific protein 11(gene name synonym)|uniprotkb:YHL022C(locus name)	psi-mi:re104_yeast(display_long)|uniprotkb:REC104(gene name)|psi-mi:REC104(display_short)|uniprotkb:YHR157W(locus name)	psi-mi:"MI:0018"(two hybrid)	Arora et al. (2004)	imex:IM-26321|pubmed:14992724	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16715622|imex:IM-26321-53	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011841.1|sgd:S000001014|ensemblfungi:YHL022C_mRNA(transcript)|go:"GO:0000228"(nuclear chromosome)|ensemblfungi:YHL022C(gene)|go:"GO:0000706"(meiotic DNA double-strand break processing)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003918"("DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0016889"(endodeoxyribonuclease activity, producing 3'-phosphomonoesters)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0045027"(DNA end binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR002815(Spo11/DNA topoisomerase VI, subunit A)|interpro:IPR013049(Spo11/DNA topoisomerase VI, subunit A, N-terminal)|interpro:IPR034136|interpro:IPR036078|interpro:IPR036388|dip:DIP-1652N	ensemblfungi:YHR157W(gene)|ensemblfungi:YHR157W_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0042138"(meiotic DNA double-strand break formation)|interpro:IPR035349|dip:DIP-7960N|refseq:NP_012027.1|sgd:S000001200	-	-	-	figure legend:Figure 7B-1|comment:The GAL4-AD fusion could be N or C terminal- not stated.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/11/17	2017/12/21	rogid:EYHgcIj0CpPlo8u5DQTW1uK30M4559292	rogid:izd4XKs93wK7fXBQxDnwyI172/w559292	rigid:o1Y/mH4Tj235NDpnPPf51wAQovE	false	lexa dna binding domain:n-n	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P23179	uniprotkb:Q02793	intact:EBI-17705|uniprotkb:D3DKP3|ensemblfungi:YHL022C	intact:EBI-17260|uniprotkb:D6VTU2|ensemblfungi:YGL213C	psi-mi:spo11_yeast(display_long)|uniprotkb:SPO11(gene name)|psi-mi:SPO11(display_short)|uniprotkb:Sporulation-specific protein 11(gene name synonym)|uniprotkb:YHL022C(locus name)	psi-mi:ski8_yeast(display_long)|uniprotkb:YGL213C(locus name)|uniprotkb:SKI8(gene name)|psi-mi:SKI8(display_short)|uniprotkb:REC103(gene name synonym)|uniprotkb:Superkiller protein 8(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Arora et al. (2004)	imex:IM-26321|pubmed:14992724	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16715622|imex:IM-26321-53	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011841.1|sgd:S000001014|ensemblfungi:YHL022C_mRNA(transcript)|go:"GO:0000228"(nuclear chromosome)|ensemblfungi:YHL022C(gene)|go:"GO:0000706"(meiotic DNA double-strand break processing)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003918"("DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0016889"(endodeoxyribonuclease activity, producing 3'-phosphomonoesters)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0045027"(DNA end binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR002815(Spo11/DNA topoisomerase VI, subunit A)|interpro:IPR013049(Spo11/DNA topoisomerase VI, subunit A, N-terminal)|interpro:IPR034136|interpro:IPR036078|interpro:IPR036388|dip:DIP-1652N	refseq:NP_011302.1|sgd:S000003181|ensemblfungi:YGL213C(gene)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034622"|go:"GO:0051607"(defense response to virus)|go:"GO:0055087"(Ski complex)|go:"GO:0065004"(protein-DNA complex assembly)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|rcsb pdb:1S4U|rcsb pdb:1SQ9|rcsb pdb:4BUJ|rcsb pdb:5MC6|reactome:R-SCE-429958|reactome:R-SCE-674695|reactome:R-SCE-75955|ensemblfungi:YGL213C_mRNA(transcript)|dip:DIP-1653N|mint:Q02793	-	-	crc64:C5E7B9D2268F9727	figure legend:Figure 7B-1|comment:The GAL4-AD fusion could be N or C terminal- not stated.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/11/17	2017/12/21	rogid:EYHgcIj0CpPlo8u5DQTW1uK30M4559292	rogid:6K6FJYcctdlT1321Nv6pOnQPwq8559292	rigid:o1Y/mH4Tj235NDpnPPf51wAQovE	false	lexa dna binding domain:n-n	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P23179	uniprotkb:P33323	intact:EBI-17705|uniprotkb:D3DKP3|ensemblfungi:YHL022C	intact:EBI-16412992|ensemblfungi:YHR157W|uniprotkb:D3DLA6	psi-mi:spo11_yeast(display_long)|uniprotkb:SPO11(gene name)|psi-mi:SPO11(display_short)|uniprotkb:Sporulation-specific protein 11(gene name synonym)|uniprotkb:YHL022C(locus name)	psi-mi:re104_yeast(display_long)|uniprotkb:REC104(gene name)|psi-mi:REC104(display_short)|uniprotkb:YHR157W(locus name)	psi-mi:"MI:0018"(two hybrid)	Arora et al. (2004)	imex:IM-26321|pubmed:14992724	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16715632|imex:IM-26321-17	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011841.1|sgd:S000001014|ensemblfungi:YHL022C_mRNA(transcript)|go:"GO:0000228"(nuclear chromosome)|ensemblfungi:YHL022C(gene)|go:"GO:0000706"(meiotic DNA double-strand break processing)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003918"("DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0016889"(endodeoxyribonuclease activity, producing 3'-phosphomonoesters)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0045027"(DNA end binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR002815(Spo11/DNA topoisomerase VI, subunit A)|interpro:IPR013049(Spo11/DNA topoisomerase VI, subunit A, N-terminal)|interpro:IPR034136|interpro:IPR036078|interpro:IPR036388|dip:DIP-1652N	ensemblfungi:YHR157W(gene)|ensemblfungi:YHR157W_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0042138"(meiotic DNA double-strand break formation)|interpro:IPR035349|dip:DIP-7960N|refseq:NP_012027.1|sgd:S000001200	-	-	-	figure legend:Figure 7B-2|comment:The GAL4-AD fusion could be N or C terminal- not stated.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/11/17	2018/01/05	rogid:EYHgcIj0CpPlo8u5DQTW1uK30M4559292	rogid:izd4XKs93wK7fXBQxDnwyI172/w559292	rigid:dR7fHMq70U3A9Gbb5QpQ8lS0LcM	false	lexa dna binding domain:n-n	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P23179	uniprotkb:Q02721	intact:EBI-17705|uniprotkb:D3DKP3|ensemblfungi:YHL022C	intact:EBI-14432|ensemblfungi:YLR329W|uniprotkb:D6VYX1	psi-mi:spo11_yeast(display_long)|uniprotkb:SPO11(gene name)|psi-mi:SPO11(display_short)|uniprotkb:Sporulation-specific protein 11(gene name synonym)|uniprotkb:YHL022C(locus name)	psi-mi:to6bl_yeast(display_long)|uniprotkb:L8543.17(orf name)|uniprotkb:YLR329W(locus name)|uniprotkb:REC102(gene name)|psi-mi:REC102(display_short)	psi-mi:"MI:0018"(two hybrid)	Arora et al. (2004)	imex:IM-26321|pubmed:14992724	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16715632|imex:IM-26321-17	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011841.1|sgd:S000001014|ensemblfungi:YHL022C_mRNA(transcript)|go:"GO:0000228"(nuclear chromosome)|ensemblfungi:YHL022C(gene)|go:"GO:0000706"(meiotic DNA double-strand break processing)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003918"("DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0016889"(endodeoxyribonuclease activity, producing 3'-phosphomonoesters)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0045027"(DNA end binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR002815(Spo11/DNA topoisomerase VI, subunit A)|interpro:IPR013049(Spo11/DNA topoisomerase VI, subunit A, N-terminal)|interpro:IPR034136|interpro:IPR036078|interpro:IPR036388|dip:DIP-1652N	sgd:S000004321|ensemblfungi:YLR329W(gene)|ensemblfungi:YLR329W_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0042138"(meiotic DNA double-strand break formation)|refseq:NP_013433.2|dip:DIP-4675N	-	-	-	figure legend:Figure 7B-2|comment:The GAL4-AD fusion could be N or C terminal- not stated.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/11/17	2018/01/05	rogid:EYHgcIj0CpPlo8u5DQTW1uK30M4559292	rogid:VmAThA+J0AAeMMGfpZCGNMxEcY8559292	rigid:dR7fHMq70U3A9Gbb5QpQ8lS0LcM	false	lexa dna binding domain:n-n	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q02793	uniprotkb:P23179	intact:EBI-17260|uniprotkb:D6VTU2|ensemblfungi:YGL213C	intact:EBI-17705|uniprotkb:D3DKP3|ensemblfungi:YHL022C	psi-mi:ski8_yeast(display_long)|uniprotkb:YGL213C(locus name)|uniprotkb:SKI8(gene name)|psi-mi:SKI8(display_short)|uniprotkb:REC103(gene name synonym)|uniprotkb:Superkiller protein 8(gene name synonym)	psi-mi:spo11_yeast(display_long)|uniprotkb:SPO11(gene name)|psi-mi:SPO11(display_short)|uniprotkb:Sporulation-specific protein 11(gene name synonym)|uniprotkb:YHL022C(locus name)	psi-mi:"MI:0018"(two hybrid)	Arora et al. (2004)	imex:IM-26321|pubmed:14992724	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16715640|imex:IM-26321-69	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011302.1|sgd:S000003181|ensemblfungi:YGL213C(gene)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034622"|go:"GO:0051607"(defense response to virus)|go:"GO:0055087"(Ski complex)|go:"GO:0065004"(protein-DNA complex assembly)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|rcsb pdb:1S4U|rcsb pdb:1SQ9|rcsb pdb:4BUJ|rcsb pdb:5MC6|reactome:R-SCE-429958|reactome:R-SCE-674695|reactome:R-SCE-75955|ensemblfungi:YGL213C_mRNA(transcript)|dip:DIP-1653N|mint:Q02793	refseq:NP_011841.1|sgd:S000001014|ensemblfungi:YHL022C_mRNA(transcript)|go:"GO:0000228"(nuclear chromosome)|ensemblfungi:YHL022C(gene)|go:"GO:0000706"(meiotic DNA double-strand break processing)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003918"("DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0016889"(endodeoxyribonuclease activity, producing 3'-phosphomonoesters)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0045027"(DNA end binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR002815(Spo11/DNA topoisomerase VI, subunit A)|interpro:IPR013049(Spo11/DNA topoisomerase VI, subunit A, N-terminal)|interpro:IPR034136|interpro:IPR036078|interpro:IPR036388|dip:DIP-1652N	-	crc64:C5E7B9D2268F9727	-	figure legend:Supplementary table 2-weak, Figure 7C-1|comment:It is not possible to identify if fusions were N or C terminal.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/11/17	2017/12/21	rogid:6K6FJYcctdlT1321Nv6pOnQPwq8559292	rogid:EYHgcIj0CpPlo8u5DQTW1uK30M4559292	rigid:o1Y/mH4Tj235NDpnPPf51wAQovE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q02793	uniprotkb:P33323	intact:EBI-17260|uniprotkb:D6VTU2|ensemblfungi:YGL213C	intact:EBI-16412992|ensemblfungi:YHR157W|uniprotkb:D3DLA6	psi-mi:ski8_yeast(display_long)|uniprotkb:YGL213C(locus name)|uniprotkb:SKI8(gene name)|psi-mi:SKI8(display_short)|uniprotkb:REC103(gene name synonym)|uniprotkb:Superkiller protein 8(gene name synonym)	psi-mi:re104_yeast(display_long)|uniprotkb:REC104(gene name)|psi-mi:REC104(display_short)|uniprotkb:YHR157W(locus name)	psi-mi:"MI:0018"(two hybrid)	Arora et al. (2004)	imex:IM-26321|pubmed:14992724	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16715640|imex:IM-26321-69	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011302.1|sgd:S000003181|ensemblfungi:YGL213C(gene)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034622"|go:"GO:0051607"(defense response to virus)|go:"GO:0055087"(Ski complex)|go:"GO:0065004"(protein-DNA complex assembly)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|rcsb pdb:1S4U|rcsb pdb:1SQ9|rcsb pdb:4BUJ|rcsb pdb:5MC6|reactome:R-SCE-429958|reactome:R-SCE-674695|reactome:R-SCE-75955|ensemblfungi:YGL213C_mRNA(transcript)|dip:DIP-1653N|mint:Q02793	ensemblfungi:YHR157W(gene)|ensemblfungi:YHR157W_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0042138"(meiotic DNA double-strand break formation)|interpro:IPR035349|dip:DIP-7960N|refseq:NP_012027.1|sgd:S000001200	-	crc64:C5E7B9D2268F9727	-	figure legend:Supplementary table 2-weak, Figure 7C-1|comment:It is not possible to identify if fusions were N or C terminal.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/11/17	2017/12/21	rogid:6K6FJYcctdlT1321Nv6pOnQPwq8559292	rogid:izd4XKs93wK7fXBQxDnwyI172/w559292	rigid:o1Y/mH4Tj235NDpnPPf51wAQovE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q02793	uniprotkb:P23179	intact:EBI-17260|uniprotkb:D6VTU2|ensemblfungi:YGL213C	intact:EBI-17705|uniprotkb:D3DKP3|ensemblfungi:YHL022C	psi-mi:ski8_yeast(display_long)|uniprotkb:YGL213C(locus name)|uniprotkb:SKI8(gene name)|psi-mi:SKI8(display_short)|uniprotkb:REC103(gene name synonym)|uniprotkb:Superkiller protein 8(gene name synonym)	psi-mi:spo11_yeast(display_long)|uniprotkb:SPO11(gene name)|psi-mi:SPO11(display_short)|uniprotkb:Sporulation-specific protein 11(gene name synonym)|uniprotkb:YHL022C(locus name)	psi-mi:"MI:0018"(two hybrid)	Arora et al. (2004)	imex:IM-26321|pubmed:14992724	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16715650|imex:IM-26321-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011302.1|sgd:S000003181|ensemblfungi:YGL213C(gene)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034622"|go:"GO:0051607"(defense response to virus)|go:"GO:0055087"(Ski complex)|go:"GO:0065004"(protein-DNA complex assembly)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|rcsb pdb:1S4U|rcsb pdb:1SQ9|rcsb pdb:4BUJ|rcsb pdb:5MC6|reactome:R-SCE-429958|reactome:R-SCE-674695|reactome:R-SCE-75955|ensemblfungi:YGL213C_mRNA(transcript)|dip:DIP-1653N|mint:Q02793	refseq:NP_011841.1|sgd:S000001014|ensemblfungi:YHL022C_mRNA(transcript)|go:"GO:0000228"(nuclear chromosome)|ensemblfungi:YHL022C(gene)|go:"GO:0000706"(meiotic DNA double-strand break processing)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003918"("DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0016889"(endodeoxyribonuclease activity, producing 3'-phosphomonoesters)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0045027"(DNA end binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR002815(Spo11/DNA topoisomerase VI, subunit A)|interpro:IPR013049(Spo11/DNA topoisomerase VI, subunit A, N-terminal)|interpro:IPR034136|interpro:IPR036078|interpro:IPR036388|dip:DIP-1652N	-	crc64:C5E7B9D2268F9727	-	figure legend:Supplementary table 2-weak, Figure 7C-2|comment:It is not possible to identify if fusions were N or C terminal.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/11/17	2018/01/05	rogid:6K6FJYcctdlT1321Nv6pOnQPwq8559292	rogid:EYHgcIj0CpPlo8u5DQTW1uK30M4559292	rigid:o1Y/mH4Tj235NDpnPPf51wAQovE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q02793	uniprotkb:P33323	intact:EBI-17260|uniprotkb:D6VTU2|ensemblfungi:YGL213C	intact:EBI-16412992|ensemblfungi:YHR157W|uniprotkb:D3DLA6	psi-mi:ski8_yeast(display_long)|uniprotkb:YGL213C(locus name)|uniprotkb:SKI8(gene name)|psi-mi:SKI8(display_short)|uniprotkb:REC103(gene name synonym)|uniprotkb:Superkiller protein 8(gene name synonym)	psi-mi:re104_yeast(display_long)|uniprotkb:REC104(gene name)|psi-mi:REC104(display_short)|uniprotkb:YHR157W(locus name)	psi-mi:"MI:0018"(two hybrid)	Arora et al. (2004)	imex:IM-26321|pubmed:14992724	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16715650|imex:IM-26321-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011302.1|sgd:S000003181|ensemblfungi:YGL213C(gene)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034622"|go:"GO:0051607"(defense response to virus)|go:"GO:0055087"(Ski complex)|go:"GO:0065004"(protein-DNA complex assembly)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|rcsb pdb:1S4U|rcsb pdb:1SQ9|rcsb pdb:4BUJ|rcsb pdb:5MC6|reactome:R-SCE-429958|reactome:R-SCE-674695|reactome:R-SCE-75955|ensemblfungi:YGL213C_mRNA(transcript)|dip:DIP-1653N|mint:Q02793	ensemblfungi:YHR157W(gene)|ensemblfungi:YHR157W_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0042138"(meiotic DNA double-strand break formation)|interpro:IPR035349|dip:DIP-7960N|refseq:NP_012027.1|sgd:S000001200	-	crc64:C5E7B9D2268F9727	-	figure legend:Supplementary table 2-weak, Figure 7C-2|comment:It is not possible to identify if fusions were N or C terminal.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/11/17	2018/01/05	rogid:6K6FJYcctdlT1321Nv6pOnQPwq8559292	rogid:izd4XKs93wK7fXBQxDnwyI172/w559292	rigid:o1Y/mH4Tj235NDpnPPf51wAQovE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q02721	uniprotkb:P49959	intact:EBI-14432|ensemblfungi:YLR329W|uniprotkb:D6VYX1	intact:EBI-396513|uniprotkb:O43475|uniprotkb:B3KTC7|ensembl:ENSP00000325863	psi-mi:to6bl_yeast(display_long)|uniprotkb:L8543.17(orf name)|uniprotkb:YLR329W(locus name)|uniprotkb:REC102(gene name)|psi-mi:REC102(display_short)	psi-mi:mre11_human(display_long)|uniprotkb:MRE11(gene name)|psi-mi:MRE11(display_short)|uniprotkb:Double-strand break repair protein MRE11A(gene name synonym)|uniprotkb:HNGS1(gene name synonym)|uniprotkb:MRE11A(gene name synonym)|uniprotkb:Meiotic recombination 11 homolog 1(gene name synonym)|uniprotkb:Meiotic recombination 11 homolog A(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Arora et al. (2004)	imex:IM-26321|pubmed:14992724	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16715656|imex:IM-26321-31	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000004321|ensemblfungi:YLR329W(gene)|ensemblfungi:YLR329W_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0042138"(meiotic DNA double-strand break formation)|refseq:NP_013433.2|dip:DIP-4675N	refseq:NP_005581.2|refseq:NP_005582.1|refseq:XP_011541139.1|refseq:XP_016873261.1|dip:DIP-33238N|ensembl:ENSG00000020922(gene)|ensembl:ENST00000323929(transcript)|go:"GO:0000014"(single-stranded DNA endodeoxyribonuclease activity)|go:"GO:0000019"(regulation of mitotic recombination)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0004518"(nuclease activity)|go:"GO:0004520"(endodeoxyribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006310"(DNA recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008296"(3'-5'-exodeoxyribonuclease activity)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0008409"(5'-3' exonuclease activity)|go:"GO:0016605"(PML body)|go:"GO:0030145"(manganese ion binding)|go:"GO:0030870"(Mre11 complex)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0031860"(telomeric 3' overhang formation)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032206"(positive regulation of telomere maintenance)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045296"(cadherin binding)|go:"GO:0097552"(mitochondrial double-strand break repair via homologous recombination)|go:"GO:0110025"(DNA strand resection involved in replication fork processing)|interpro:IPR003701(DNA repair exonuclease)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR007281(Mre11, DNA-binding)|interpro:IPR029052|interpro:IPR038487|interpro:IPR041796|mint:P49959|rcsb pdb:3T1I|reactome:R-HSA-1834949|reactome:R-HSA-2559586|reactome:R-HSA-3270619|reactome:R-HSA-5685938|reactome:R-HSA-5685939|reactome:R-HSA-5685942|reactome:R-HSA-5693548|reactome:R-HSA-5693554|reactome:R-HSA-5693565|reactome:R-HSA-5693568|reactome:R-HSA-5693571|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|reactome:R-HSA-912446	-	-	-	figure legend:Figure 1B -weak1|comment:weak  interaction|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/11/17	2017/12/21	rogid:VmAThA+J0AAeMMGfpZCGNMxEcY8559292	rogid:fgwgA0BcNZ9phGBaOSYjkldDgeI9606	rigid:wTyztv5euO/ZpQ2Obr56R6vFy/c	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P49959	uniprotkb:P33323	intact:EBI-396513|uniprotkb:O43475|uniprotkb:B3KTC7|ensembl:ENSP00000325863	intact:EBI-16412992|ensemblfungi:YHR157W|uniprotkb:D3DLA6	psi-mi:mre11_human(display_long)|uniprotkb:MRE11(gene name)|psi-mi:MRE11(display_short)|uniprotkb:Double-strand break repair protein MRE11A(gene name synonym)|uniprotkb:HNGS1(gene name synonym)|uniprotkb:MRE11A(gene name synonym)|uniprotkb:Meiotic recombination 11 homolog 1(gene name synonym)|uniprotkb:Meiotic recombination 11 homolog A(gene name synonym)	psi-mi:re104_yeast(display_long)|uniprotkb:REC104(gene name)|psi-mi:REC104(display_short)|uniprotkb:YHR157W(locus name)	psi-mi:"MI:0018"(two hybrid)	Arora et al. (2004)	imex:IM-26321|pubmed:14992724	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16715662|imex:IM-26321-33	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005581.2|refseq:NP_005582.1|refseq:XP_011541139.1|refseq:XP_016873261.1|dip:DIP-33238N|ensembl:ENSG00000020922(gene)|ensembl:ENST00000323929(transcript)|go:"GO:0000014"(single-stranded DNA endodeoxyribonuclease activity)|go:"GO:0000019"(regulation of mitotic recombination)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0004518"(nuclease activity)|go:"GO:0004520"(endodeoxyribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006310"(DNA recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008296"(3'-5'-exodeoxyribonuclease activity)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0008409"(5'-3' exonuclease activity)|go:"GO:0016605"(PML body)|go:"GO:0030145"(manganese ion binding)|go:"GO:0030870"(Mre11 complex)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0031860"(telomeric 3' overhang formation)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032206"(positive regulation of telomere maintenance)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045296"(cadherin binding)|go:"GO:0097552"(mitochondrial double-strand break repair via homologous recombination)|go:"GO:0110025"(DNA strand resection involved in replication fork processing)|interpro:IPR003701(DNA repair exonuclease)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR007281(Mre11, DNA-binding)|interpro:IPR029052|interpro:IPR038487|interpro:IPR041796|mint:P49959|rcsb pdb:3T1I|reactome:R-HSA-1834949|reactome:R-HSA-2559586|reactome:R-HSA-3270619|reactome:R-HSA-5685938|reactome:R-HSA-5685939|reactome:R-HSA-5685942|reactome:R-HSA-5693548|reactome:R-HSA-5693554|reactome:R-HSA-5693565|reactome:R-HSA-5693568|reactome:R-HSA-5693571|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|reactome:R-HSA-912446	ensemblfungi:YHR157W(gene)|ensemblfungi:YHR157W_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0042138"(meiotic DNA double-strand break formation)|interpro:IPR035349|dip:DIP-7960N|refseq:NP_012027.1|sgd:S000001200	-	-	-	figure legend:Figure 1B -weak2|comment:weak interaction|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/11/17	2017/12/21	rogid:fgwgA0BcNZ9phGBaOSYjkldDgeI9606	rogid:izd4XKs93wK7fXBQxDnwyI172/w559292	rigid:iKIo7rM2jrDpEm3VEUaXsfCbNaA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P33323	uniprotkb:P29467	intact:EBI-16412992|ensemblfungi:YHR157W|uniprotkb:D3DLA6	intact:EBI-2566907|uniprotkb:P87265|uniprotkb:D3DLU5|ensemblfungi:YER044C-A	psi-mi:re104_yeast(display_long)|uniprotkb:REC104(gene name)|psi-mi:REC104(display_short)|uniprotkb:YHR157W(locus name)	psi-mi:mei4_yeast(display_long)|uniprotkb:MEI4(gene name)|psi-mi:MEI4(display_short)|uniprotkb:YER044BC(orf name)|uniprotkb:YER044C-A(locus name)	psi-mi:"MI:0018"(two hybrid)	Arora et al. (2004)	imex:IM-26321|pubmed:14992724	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16718456|imex:IM-26321-39	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YHR157W(gene)|ensemblfungi:YHR157W_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0042138"(meiotic DNA double-strand break formation)|interpro:IPR035349|dip:DIP-7960N|refseq:NP_012027.1|sgd:S000001200	sgd:S000001954|refseq:NP_010963.1|ensemblfungi:YER044C-A(gene)|ensemblfungi:YER044C-A_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0006310"(DNA recombination)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0042138"(meiotic DNA double-strand break formation)|interpro:IPR025888	-	-	-	figure legend:Figure 1B -weak|comment:weak  interaction|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/11/17	2018/01/08	rogid:izd4XKs93wK7fXBQxDnwyI172/w559292	rogid:A9neKqDQ4o5xP4QUOSRJQvJetnY559292	rigid:2MqFnqok+vSL3zFwgaG5QzeN6F0	false	gal4 activation domain:?-?	lexa dna binding domain:c-c	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)