#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B intact:EBI-7355238 uniprotkb:P63000-1 intact:MINT-1206864 intact:EBI-7212896|uniprotkb:P15154-1|intact:MINT-124079|ensembl:ENSP00000258737 psi-mi:q85737_9hiv1(display_short)|psi-mi:EBI-7355238(display_long) psi-mi:p63000-1(display_long)|uniprotkb:RAC1(gene name)|psi-mi:RAC1(display_short)|uniprotkb:Cell migration-inducing gene 5 protein(gene name synonym)|uniprotkb:Ras-like protein TC25(gene name synonym)|uniprotkb:TC25(gene name synonym)|uniprotkb:p21-Rac1(gene name synonym)|uniprotkb:MIG5(orf name)|uniprotkb:Rac1A(isoform synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Janardhan et al. (2004) pubmed:14737186|doi:10.1371/journal.pbio.0020006|imex:IM-13619 taxid:11676(9hiv1)|taxid:11676(Human immunodeficiency virus 1) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16216852|imex:IM-13619-1|dip:DIP-102607E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q85737(uniprot-removed-ac) intact:EBI-413628(isoform-parent)|ensembl:ENSG00000136238(gene)|ensembl:ENST00000348035(transcript) psi-mi:"MI:0465"(dip) no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.|caution:This sequence has been withdrawn from Uniprot.|no-uniprot-update:|comment:mint comment:mint full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/09 2017/08/10 rogid:T1QrlTN0bSeFp4VLvOxCyFReA2E11676 rogid:8rkYyZSFL5tIfbRNKZgP/UDxD+A9606 rigid:H1NvPvncIcIqJ8ER52FDroTBL9Y false flag tag:0-0 myc tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) intact:EBI-7355238 uniprotkb:Q92556-1 intact:MINT-1206864 intact:EBI-15668002|ensembl:ENSP00000312185|ensembl:ENSP00000394458|ensembl:ENSP00000406952 psi-mi:q85737_9hiv1(display_short)|psi-mi:EBI-7355238(display_long) psi-mi:q92556-1(display_long)|uniprotkb:ELMO1(gene name)|psi-mi:ELMO1(display_short)|uniprotkb:KIAA0281(gene name synonym)|uniprotkb:Protein ced-12 homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Janardhan et al. (2004) pubmed:14737186|doi:10.1371/journal.pbio.0020006|imex:IM-13619 taxid:11676(9hiv1)|taxid:11676(Human immunodeficiency virus 1) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16216852|imex:IM-13619-1|dip:DIP-102607E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q85737(uniprot-removed-ac) intact:EBI-346417(isoform-parent)|ensembl:ENSG00000155849(gene)|ensembl:ENST00000310758(transcript)|ensembl:ENST00000442504(transcript)|ensembl:ENST00000448602(transcript) psi-mi:"MI:0465"(dip) no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.|caution:This sequence has been withdrawn from Uniprot.|no-uniprot-update:|comment:mint - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/09 2017/08/10 rogid:T1QrlTN0bSeFp4VLvOxCyFReA2E11676 rogid:sW9Vj+Vej/oJb9qQxkbtIipDYXI9606 rigid:H1NvPvncIcIqJ8ER52FDroTBL9Y false flag tag:0-0 myc tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) intact:EBI-7355238 uniprotkb:Q92608 intact:MINT-1206864 intact:EBI-448771|uniprotkb:Q2M3I0|uniprotkb:Q96AK7|ensembl:ENSP00000429283 psi-mi:q85737_9hiv1(display_short)|psi-mi:EBI-7355238(display_long) psi-mi:dock2_human(display_long)|uniprotkb:DOCK2(gene name)|psi-mi:DOCK2(display_short)|uniprotkb:KIAA0209(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Janardhan et al. (2004) pubmed:14737186|doi:10.1371/journal.pbio.0020006|imex:IM-13619 taxid:11676(9hiv1)|taxid:11676(Human immunodeficiency virus 1) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16216852|imex:IM-13619-1|dip:DIP-102607E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q85737(uniprot-removed-ac) refseq:NP_004937.1|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001452(Src homology-3)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026791|interpro:IPR026799|interpro:IPR027007|interpro:IPR027357|interpro:IPR032376|interpro:IPR035892|interpro:IPR036028|interpro:IPR042455|interpro:IPR043161|interpro:IPR043162|go:"GO:0046633"(alpha-beta T cell proliferation)|mint:Q92608|rcsb pdb:2RQR|rcsb pdb:2YIN|rcsb pdb:3A98|rcsb pdb:3B13|rcsb pdb:6TGB|rcsb pdb:6TGC|reactome:R-HSA-164944|reactome:R-HSA-6798695|reactome:R-HSA-8980692|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-983231|ensembl:ENSG00000134516(gene)|go:"GO:0001766"(membrane raft polarization)|go:"GO:0001768"(establishment of T cell polarity)|go:"GO:0001771"(immunological synapse formation)|go:"GO:0002277"(myeloid dendritic cell activation involved in immune response)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006935"(chemotaxis)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0035580"(specific granule lumen)|go:"GO:0042608"(T cell receptor binding)|go:"GO:0044351"(macropinocytosis)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|ensembl:ENST00000520908(transcript)|dip:DIP-31791N psi-mi:"MI:0465"(dip) no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.|caution:This sequence has been withdrawn from Uniprot.|no-uniprot-update:|comment:mint - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/09 2017/08/10 rogid:T1QrlTN0bSeFp4VLvOxCyFReA2E11676 rogid:0GZlR6TI1N3mi2VBXsq3M6DJGpQ9606 rigid:H1NvPvncIcIqJ8ER52FDroTBL9Y false flag tag:0-0 his tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q02840 uniprotkb:P15153 intact:EBI-16216903 intact:EBI-489652|ensembl:ENSP00000249071|uniprotkb:Q9UDJ4 psi-mi:nef_sivg1(display_long)|uniprotkb:nef(gene name)|psi-mi:nef(display_short)|uniprotkb:3'ORF(gene name synonym)|uniprotkb:Negative factor(gene name synonym) psi-mi:rac2_human(display_long)|uniprotkb:p21-Rac2(gene name synonym)|uniprotkb:Small G protein(gene name synonym)|uniprotkb:GX(gene name synonym)|uniprotkb:RAC2(gene name)|psi-mi:RAC2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Janardhan et al. (2004) pubmed:14737186|doi:10.1371/journal.pbio.0020006|imex:IM-13619 taxid:31684(sivg1)|taxid:31684(sivg1) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16216918|imex:IM-13619-3|dip:DIP-102608E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005525"(GTP binding)|go:"GO:0016020"(membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|interpro:IPR001558(HIV negative factor Nef)|interpro:IPR027481|refseq:NP_054373.1 go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0045453"(bone resorption)|go:"GO:0060263"(regulation of respiratory burst)|go:"GO:0060753"(regulation of mast cell chemotaxis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071593"(lymphocyte aggregation)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902622"(regulation of neutrophil migration)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P15153|rcsb pdb:1DS6|rcsb pdb:2W2T|rcsb pdb:2W2V|rcsb pdb:2W2X|reactome:R-HSA-114604|reactome:R-HSA-1222556|go:"GO:0043304"(regulation of mast cell degranulation)|ensembl:ENSG00000128340(gene)|ensembl:ENST00000249071(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007165"(signal transduction)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010310"(regulation of hydrogen peroxide metabolic process)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010810"(regulation of cell-substrate adhesion)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0005925"(focal adhesion)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0042129"(regulation of T cell proliferation)|go:"GO:0042995"(cell projection)|go:"GO:0043231"(intracellular membrane-bounded organelle)|reactome:R-HSA-1257604|refseq:NP_002863.1|reactome:R-HSA-2219530|reactome:R-HSA-4086400|reactome:R-HSA-5668599|reactome:R-HSA-6811558|reactome:R-HSA-9013404|dip:DIP-34291N psi-mi:"MI:0465"(dip) crc64:80E7B0175C5923FD - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/09 2017/08/10 rogid:IcRlbKWJyE56bNH9nNHrrxt/TZU31684 rogid:NYkPt/WNmKM3qAhhaufLCPkc/io9606 rigid:X1Ex9pZpLMaeiGgvH8NbRXnB/So false flag tag:c-c myc tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q02840 uniprotkb:Q92556-1 intact:EBI-16216903 intact:EBI-15668002|ensembl:ENSP00000312185|ensembl:ENSP00000394458|ensembl:ENSP00000406952 psi-mi:nef_sivg1(display_long)|uniprotkb:nef(gene name)|psi-mi:nef(display_short)|uniprotkb:3'ORF(gene name synonym)|uniprotkb:Negative factor(gene name synonym) psi-mi:q92556-1(display_long)|uniprotkb:ELMO1(gene name)|psi-mi:ELMO1(display_short)|uniprotkb:KIAA0281(gene name synonym)|uniprotkb:Protein ced-12 homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Janardhan et al. (2004) pubmed:14737186|doi:10.1371/journal.pbio.0020006|imex:IM-13619 taxid:31684(sivg1)|taxid:31684(sivg1) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16216918|imex:IM-13619-3|dip:DIP-102608E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005525"(GTP binding)|go:"GO:0016020"(membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|interpro:IPR001558(HIV negative factor Nef)|interpro:IPR027481|refseq:NP_054373.1 intact:EBI-346417(isoform-parent)|ensembl:ENSG00000155849(gene)|ensembl:ENST00000310758(transcript)|ensembl:ENST00000442504(transcript)|ensembl:ENST00000448602(transcript) psi-mi:"MI:0465"(dip) crc64:80E7B0175C5923FD - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/09 2017/08/10 rogid:IcRlbKWJyE56bNH9nNHrrxt/TZU31684 rogid:sW9Vj+Vej/oJb9qQxkbtIipDYXI9606 rigid:X1Ex9pZpLMaeiGgvH8NbRXnB/So false flag tag:c-c myc tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q02840 uniprotkb:Q92608 intact:EBI-16216903 intact:EBI-448771|uniprotkb:Q2M3I0|uniprotkb:Q96AK7|ensembl:ENSP00000429283 psi-mi:nef_sivg1(display_long)|uniprotkb:nef(gene name)|psi-mi:nef(display_short)|uniprotkb:3'ORF(gene name synonym)|uniprotkb:Negative factor(gene name synonym) psi-mi:dock2_human(display_long)|uniprotkb:DOCK2(gene name)|psi-mi:DOCK2(display_short)|uniprotkb:KIAA0209(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Janardhan et al. (2004) pubmed:14737186|doi:10.1371/journal.pbio.0020006|imex:IM-13619 taxid:31684(sivg1)|taxid:31684(sivg1) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16216918|imex:IM-13619-3|dip:DIP-102608E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005525"(GTP binding)|go:"GO:0016020"(membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|interpro:IPR001558(HIV negative factor Nef)|interpro:IPR027481|refseq:NP_054373.1 refseq:NP_004937.1|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001452(Src homology-3)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026791|interpro:IPR026799|interpro:IPR027007|interpro:IPR027357|interpro:IPR032376|interpro:IPR035892|interpro:IPR036028|interpro:IPR042455|interpro:IPR043161|interpro:IPR043162|go:"GO:0046633"(alpha-beta T cell proliferation)|mint:Q92608|rcsb pdb:2RQR|rcsb pdb:2YIN|rcsb pdb:3A98|rcsb pdb:3B13|rcsb pdb:6TGB|rcsb pdb:6TGC|reactome:R-HSA-164944|reactome:R-HSA-6798695|reactome:R-HSA-8980692|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-983231|ensembl:ENSG00000134516(gene)|go:"GO:0001766"(membrane raft polarization)|go:"GO:0001768"(establishment of T cell polarity)|go:"GO:0001771"(immunological synapse formation)|go:"GO:0002277"(myeloid dendritic cell activation involved in immune response)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006935"(chemotaxis)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0035580"(specific granule lumen)|go:"GO:0042608"(T cell receptor binding)|go:"GO:0044351"(macropinocytosis)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|ensembl:ENST00000520908(transcript)|dip:DIP-31791N psi-mi:"MI:0465"(dip) crc64:80E7B0175C5923FD - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/09 2017/08/10 rogid:IcRlbKWJyE56bNH9nNHrrxt/TZU31684 rogid:0GZlR6TI1N3mi2VBXsq3M6DJGpQ9606 rigid:X1Ex9pZpLMaeiGgvH8NbRXnB/So false flag tag:c-c his tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q92608 uniprotkb:P15153 intact:EBI-448771|uniprotkb:Q2M3I0|uniprotkb:Q96AK7|ensembl:ENSP00000429283 intact:EBI-489652|ensembl:ENSP00000249071|uniprotkb:Q9UDJ4 psi-mi:dock2_human(display_long)|uniprotkb:DOCK2(gene name)|psi-mi:DOCK2(display_short)|uniprotkb:KIAA0209(gene name synonym) psi-mi:rac2_human(display_long)|uniprotkb:p21-Rac2(gene name synonym)|uniprotkb:Small G protein(gene name synonym)|uniprotkb:GX(gene name synonym)|uniprotkb:RAC2(gene name)|psi-mi:RAC2(display_short) psi-mi:"MI:0096"(pull down) Janardhan et al. (2004) pubmed:14737186|doi:10.1371/journal.pbio.0020006|imex:IM-13619 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16216945|imex:IM-13619-4|dip:DIP-102606E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004937.1|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001452(Src homology-3)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026791|interpro:IPR026799|interpro:IPR027007|interpro:IPR027357|interpro:IPR032376|interpro:IPR035892|interpro:IPR036028|interpro:IPR042455|interpro:IPR043161|interpro:IPR043162|go:"GO:0046633"(alpha-beta T cell proliferation)|mint:Q92608|rcsb pdb:2RQR|rcsb pdb:2YIN|rcsb pdb:3A98|rcsb pdb:3B13|rcsb pdb:6TGB|rcsb pdb:6TGC|reactome:R-HSA-164944|reactome:R-HSA-6798695|reactome:R-HSA-8980692|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-983231|ensembl:ENSG00000134516(gene)|go:"GO:0001766"(membrane raft polarization)|go:"GO:0001768"(establishment of T cell polarity)|go:"GO:0001771"(immunological synapse formation)|go:"GO:0002277"(myeloid dendritic cell activation involved in immune response)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006935"(chemotaxis)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0035580"(specific granule lumen)|go:"GO:0042608"(T cell receptor binding)|go:"GO:0044351"(macropinocytosis)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|ensembl:ENST00000520908(transcript)|dip:DIP-31791N go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0045453"(bone resorption)|go:"GO:0060263"(regulation of respiratory burst)|go:"GO:0060753"(regulation of mast cell chemotaxis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071593"(lymphocyte aggregation)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902622"(regulation of neutrophil migration)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P15153|rcsb pdb:1DS6|rcsb pdb:2W2T|rcsb pdb:2W2V|rcsb pdb:2W2X|reactome:R-HSA-114604|reactome:R-HSA-1222556|go:"GO:0043304"(regulation of mast cell degranulation)|ensembl:ENSG00000128340(gene)|ensembl:ENST00000249071(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007165"(signal transduction)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010310"(regulation of hydrogen peroxide metabolic process)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010810"(regulation of cell-substrate adhesion)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0005925"(focal adhesion)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0042129"(regulation of T cell proliferation)|go:"GO:0042995"(cell projection)|go:"GO:0043231"(intracellular membrane-bounded organelle)|reactome:R-HSA-1257604|refseq:NP_002863.1|reactome:R-HSA-2219530|reactome:R-HSA-4086400|reactome:R-HSA-5668599|reactome:R-HSA-6811558|reactome:R-HSA-9013404|dip:DIP-34291N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/09 2017/08/10 rogid:0GZlR6TI1N3mi2VBXsq3M6DJGpQ9606 rogid:NYkPt/WNmKM3qAhhaufLCPkc/io9606 rigid:i1gJACYE2rcW1IhMGjd0vtEGGsM false his tag:n-n myc tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q92608 uniprotkb:Q92556-1 intact:EBI-448771|uniprotkb:Q2M3I0|uniprotkb:Q96AK7|ensembl:ENSP00000429283 intact:EBI-15668002|ensembl:ENSP00000312185|ensembl:ENSP00000394458|ensembl:ENSP00000406952 psi-mi:dock2_human(display_long)|uniprotkb:DOCK2(gene name)|psi-mi:DOCK2(display_short)|uniprotkb:KIAA0209(gene name synonym) psi-mi:q92556-1(display_long)|uniprotkb:ELMO1(gene name)|psi-mi:ELMO1(display_short)|uniprotkb:KIAA0281(gene name synonym)|uniprotkb:Protein ced-12 homolog(gene name synonym) psi-mi:"MI:0096"(pull down) Janardhan et al. (2004) pubmed:14737186|doi:10.1371/journal.pbio.0020006|imex:IM-13619 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16216945|imex:IM-13619-4|dip:DIP-102606E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004937.1|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001452(Src homology-3)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026791|interpro:IPR026799|interpro:IPR027007|interpro:IPR027357|interpro:IPR032376|interpro:IPR035892|interpro:IPR036028|interpro:IPR042455|interpro:IPR043161|interpro:IPR043162|go:"GO:0046633"(alpha-beta T cell proliferation)|mint:Q92608|rcsb pdb:2RQR|rcsb pdb:2YIN|rcsb pdb:3A98|rcsb pdb:3B13|rcsb pdb:6TGB|rcsb pdb:6TGC|reactome:R-HSA-164944|reactome:R-HSA-6798695|reactome:R-HSA-8980692|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-983231|ensembl:ENSG00000134516(gene)|go:"GO:0001766"(membrane raft polarization)|go:"GO:0001768"(establishment of T cell polarity)|go:"GO:0001771"(immunological synapse formation)|go:"GO:0002277"(myeloid dendritic cell activation involved in immune response)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006935"(chemotaxis)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0035580"(specific granule lumen)|go:"GO:0042608"(T cell receptor binding)|go:"GO:0044351"(macropinocytosis)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|ensembl:ENST00000520908(transcript)|dip:DIP-31791N intact:EBI-346417(isoform-parent)|ensembl:ENSG00000155849(gene)|ensembl:ENST00000310758(transcript)|ensembl:ENST00000442504(transcript)|ensembl:ENST00000448602(transcript) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/09 2017/08/10 rogid:0GZlR6TI1N3mi2VBXsq3M6DJGpQ9606 rogid:sW9Vj+Vej/oJb9qQxkbtIipDYXI9606 rigid:i1gJACYE2rcW1IhMGjd0vtEGGsM false his tag:n-n myc tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) intact:EBI-7355238 uniprotkb:Q92608 intact:MINT-1206864 intact:EBI-448771|uniprotkb:Q2M3I0|uniprotkb:Q96AK7|ensembl:ENSP00000429283 psi-mi:q85737_9hiv1(display_short)|psi-mi:EBI-7355238(display_long) psi-mi:dock2_human(display_long)|uniprotkb:DOCK2(gene name)|psi-mi:DOCK2(display_short)|uniprotkb:KIAA0209(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Janardhan et al. (2004) pubmed:14737186|doi:10.1371/journal.pbio.0020006|imex:IM-13619 taxid:11676(9hiv1)|taxid:11676(Human immunodeficiency virus 1) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16216969|imex:IM-13619-5|dip:DIP-102609E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q85737(uniprot-removed-ac) refseq:NP_004937.1|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001452(Src homology-3)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026791|interpro:IPR026799|interpro:IPR027007|interpro:IPR027357|interpro:IPR032376|interpro:IPR035892|interpro:IPR036028|interpro:IPR042455|interpro:IPR043161|interpro:IPR043162|go:"GO:0046633"(alpha-beta T cell proliferation)|mint:Q92608|rcsb pdb:2RQR|rcsb pdb:2YIN|rcsb pdb:3A98|rcsb pdb:3B13|rcsb pdb:6TGB|rcsb pdb:6TGC|reactome:R-HSA-164944|reactome:R-HSA-6798695|reactome:R-HSA-8980692|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-983231|ensembl:ENSG00000134516(gene)|go:"GO:0001766"(membrane raft polarization)|go:"GO:0001768"(establishment of T cell polarity)|go:"GO:0001771"(immunological synapse formation)|go:"GO:0002277"(myeloid dendritic cell activation involved in immune response)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006935"(chemotaxis)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0035580"(specific granule lumen)|go:"GO:0042608"(T cell receptor binding)|go:"GO:0044351"(macropinocytosis)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|ensembl:ENST00000520908(transcript)|dip:DIP-31791N psi-mi:"MI:0465"(dip) no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.|caution:This sequence has been withdrawn from Uniprot.|no-uniprot-update:|comment:mint - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/09 2017/08/10 rogid:T1QrlTN0bSeFp4VLvOxCyFReA2E11676 rogid:0GZlR6TI1N3mi2VBXsq3M6DJGpQ9606 rigid:SEIKtb5MJD6LjujNxGC2Kto+xPs false flag tag:0-0 his tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q92608 intact:EBI-7355238 intact:EBI-448771|uniprotkb:Q2M3I0|uniprotkb:Q96AK7|ensembl:ENSP00000429283 intact:MINT-1206864 psi-mi:dock2_human(display_long)|uniprotkb:DOCK2(gene name)|psi-mi:DOCK2(display_short)|uniprotkb:KIAA0209(gene name synonym) psi-mi:q85737_9hiv1(display_short)|psi-mi:EBI-7355238(display_long) psi-mi:"MI:0096"(pull down) Janardhan et al. (2004) pubmed:14737186|doi:10.1371/journal.pbio.0020006|imex:IM-13619 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:11676(9hiv1)|taxid:11676(Human immunodeficiency virus 1) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16216990|imex:IM-13619-6|dip:DIP-102605E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004937.1|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001452(Src homology-3)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026791|interpro:IPR026799|interpro:IPR027007|interpro:IPR027357|interpro:IPR032376|interpro:IPR035892|interpro:IPR036028|interpro:IPR042455|interpro:IPR043161|interpro:IPR043162|go:"GO:0046633"(alpha-beta T cell proliferation)|mint:Q92608|rcsb pdb:2RQR|rcsb pdb:2YIN|rcsb pdb:3A98|rcsb pdb:3B13|rcsb pdb:6TGB|rcsb pdb:6TGC|reactome:R-HSA-164944|reactome:R-HSA-6798695|reactome:R-HSA-8980692|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-983231|ensembl:ENSG00000134516(gene)|go:"GO:0001766"(membrane raft polarization)|go:"GO:0001768"(establishment of T cell polarity)|go:"GO:0001771"(immunological synapse formation)|go:"GO:0002277"(myeloid dendritic cell activation involved in immune response)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006935"(chemotaxis)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0035580"(specific granule lumen)|go:"GO:0042608"(T cell receptor binding)|go:"GO:0044351"(macropinocytosis)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|ensembl:ENST00000520908(transcript)|dip:DIP-31791N uniprotkb:Q85737(uniprot-removed-ac) psi-mi:"MI:0465"(dip) - no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.|caution:This sequence has been withdrawn from Uniprot.|no-uniprot-update:|comment:mint full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/09 2017/08/10 rogid:0GZlR6TI1N3mi2VBXsq3M6DJGpQ9606 rogid:T1QrlTN0bSeFp4VLvOxCyFReA2E11676 rigid:dx107ro7EvNRDvKXgeaO9PiQfwQ false his tag:n-n flag tag:0-0 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q92608 uniprotkb:P15153 intact:EBI-448771|uniprotkb:Q2M3I0|uniprotkb:Q96AK7|ensembl:ENSP00000429283 intact:EBI-489652|ensembl:ENSP00000249071|uniprotkb:Q9UDJ4 psi-mi:dock2_human(display_long)|uniprotkb:DOCK2(gene name)|psi-mi:DOCK2(display_short)|uniprotkb:KIAA0209(gene name synonym) psi-mi:rac2_human(display_long)|uniprotkb:p21-Rac2(gene name synonym)|uniprotkb:Small G protein(gene name synonym)|uniprotkb:GX(gene name synonym)|uniprotkb:RAC2(gene name)|psi-mi:RAC2(display_short) psi-mi:"MI:0096"(pull down) Janardhan et al. (2004) pubmed:14737186|doi:10.1371/journal.pbio.0020006|imex:IM-13619 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16216990|imex:IM-13619-6|dip:DIP-102605E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004937.1|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001452(Src homology-3)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026791|interpro:IPR026799|interpro:IPR027007|interpro:IPR027357|interpro:IPR032376|interpro:IPR035892|interpro:IPR036028|interpro:IPR042455|interpro:IPR043161|interpro:IPR043162|go:"GO:0046633"(alpha-beta T cell proliferation)|mint:Q92608|rcsb pdb:2RQR|rcsb pdb:2YIN|rcsb pdb:3A98|rcsb pdb:3B13|rcsb pdb:6TGB|rcsb pdb:6TGC|reactome:R-HSA-164944|reactome:R-HSA-6798695|reactome:R-HSA-8980692|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-983231|ensembl:ENSG00000134516(gene)|go:"GO:0001766"(membrane raft polarization)|go:"GO:0001768"(establishment of T cell polarity)|go:"GO:0001771"(immunological synapse formation)|go:"GO:0002277"(myeloid dendritic cell activation involved in immune response)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006935"(chemotaxis)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0035580"(specific granule lumen)|go:"GO:0042608"(T cell receptor binding)|go:"GO:0044351"(macropinocytosis)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|ensembl:ENST00000520908(transcript)|dip:DIP-31791N go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0045453"(bone resorption)|go:"GO:0060263"(regulation of respiratory burst)|go:"GO:0060753"(regulation of mast cell chemotaxis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071593"(lymphocyte aggregation)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902622"(regulation of neutrophil migration)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P15153|rcsb pdb:1DS6|rcsb pdb:2W2T|rcsb pdb:2W2V|rcsb pdb:2W2X|reactome:R-HSA-114604|reactome:R-HSA-1222556|go:"GO:0043304"(regulation of mast cell degranulation)|ensembl:ENSG00000128340(gene)|ensembl:ENST00000249071(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007165"(signal transduction)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010310"(regulation of hydrogen peroxide metabolic process)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010810"(regulation of cell-substrate adhesion)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0005925"(focal adhesion)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0042129"(regulation of T cell proliferation)|go:"GO:0042995"(cell projection)|go:"GO:0043231"(intracellular membrane-bounded organelle)|reactome:R-HSA-1257604|refseq:NP_002863.1|reactome:R-HSA-2219530|reactome:R-HSA-4086400|reactome:R-HSA-5668599|reactome:R-HSA-6811558|reactome:R-HSA-9013404|dip:DIP-34291N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/09 2017/08/10 rogid:0GZlR6TI1N3mi2VBXsq3M6DJGpQ9606 rogid:NYkPt/WNmKM3qAhhaufLCPkc/io9606 rigid:dx107ro7EvNRDvKXgeaO9PiQfwQ false his tag:n-n myc tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q92608 uniprotkb:Q92556-1 intact:EBI-448771|uniprotkb:Q2M3I0|uniprotkb:Q96AK7|ensembl:ENSP00000429283 intact:EBI-15668002|ensembl:ENSP00000312185|ensembl:ENSP00000394458|ensembl:ENSP00000406952 psi-mi:dock2_human(display_long)|uniprotkb:DOCK2(gene name)|psi-mi:DOCK2(display_short)|uniprotkb:KIAA0209(gene name synonym) psi-mi:q92556-1(display_long)|uniprotkb:ELMO1(gene name)|psi-mi:ELMO1(display_short)|uniprotkb:KIAA0281(gene name synonym)|uniprotkb:Protein ced-12 homolog(gene name synonym) psi-mi:"MI:0096"(pull down) Janardhan et al. (2004) pubmed:14737186|doi:10.1371/journal.pbio.0020006|imex:IM-13619 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16216990|imex:IM-13619-6|dip:DIP-102605E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004937.1|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001452(Src homology-3)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026791|interpro:IPR026799|interpro:IPR027007|interpro:IPR027357|interpro:IPR032376|interpro:IPR035892|interpro:IPR036028|interpro:IPR042455|interpro:IPR043161|interpro:IPR043162|go:"GO:0046633"(alpha-beta T cell proliferation)|mint:Q92608|rcsb pdb:2RQR|rcsb pdb:2YIN|rcsb pdb:3A98|rcsb pdb:3B13|rcsb pdb:6TGB|rcsb pdb:6TGC|reactome:R-HSA-164944|reactome:R-HSA-6798695|reactome:R-HSA-8980692|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-983231|ensembl:ENSG00000134516(gene)|go:"GO:0001766"(membrane raft polarization)|go:"GO:0001768"(establishment of T cell polarity)|go:"GO:0001771"(immunological synapse formation)|go:"GO:0002277"(myeloid dendritic cell activation involved in immune response)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006935"(chemotaxis)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0035580"(specific granule lumen)|go:"GO:0042608"(T cell receptor binding)|go:"GO:0044351"(macropinocytosis)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|ensembl:ENST00000520908(transcript)|dip:DIP-31791N intact:EBI-346417(isoform-parent)|ensembl:ENSG00000155849(gene)|ensembl:ENST00000310758(transcript)|ensembl:ENST00000442504(transcript)|ensembl:ENST00000448602(transcript) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/09 2017/08/10 rogid:0GZlR6TI1N3mi2VBXsq3M6DJGpQ9606 rogid:sW9Vj+Vej/oJb9qQxkbtIipDYXI9606 rigid:dx107ro7EvNRDvKXgeaO9PiQfwQ false his tag:n-n myc tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) intact:EBI-7355238 uniprotkb:P15153 intact:MINT-1206864 intact:EBI-489652|ensembl:ENSP00000249071|uniprotkb:Q9UDJ4 psi-mi:q85737_9hiv1(display_short)|psi-mi:EBI-7355238(display_long) psi-mi:rac2_human(display_long)|uniprotkb:p21-Rac2(gene name synonym)|uniprotkb:Small G protein(gene name synonym)|uniprotkb:GX(gene name synonym)|uniprotkb:RAC2(gene name)|psi-mi:RAC2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Janardhan et al. (2004) pubmed:14737186|doi:10.1371/journal.pbio.0020006|imex:IM-13619 taxid:11676(9hiv1)|taxid:11676(Human immunodeficiency virus 1) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16216879|imex:IM-13619-2|dip:DIP-102605E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q85737(uniprot-removed-ac) go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0045453"(bone resorption)|go:"GO:0060263"(regulation of respiratory burst)|go:"GO:0060753"(regulation of mast cell chemotaxis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071593"(lymphocyte aggregation)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902622"(regulation of neutrophil migration)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P15153|rcsb pdb:1DS6|rcsb pdb:2W2T|rcsb pdb:2W2V|rcsb pdb:2W2X|reactome:R-HSA-114604|reactome:R-HSA-1222556|go:"GO:0043304"(regulation of mast cell degranulation)|ensembl:ENSG00000128340(gene)|ensembl:ENST00000249071(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007165"(signal transduction)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010310"(regulation of hydrogen peroxide metabolic process)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010810"(regulation of cell-substrate adhesion)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0005925"(focal adhesion)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0042129"(regulation of T cell proliferation)|go:"GO:0042995"(cell projection)|go:"GO:0043231"(intracellular membrane-bounded organelle)|reactome:R-HSA-1257604|refseq:NP_002863.1|reactome:R-HSA-2219530|reactome:R-HSA-4086400|reactome:R-HSA-5668599|reactome:R-HSA-6811558|reactome:R-HSA-9013404|dip:DIP-34291N psi-mi:"MI:0465"(dip) no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.|caution:This sequence has been withdrawn from Uniprot.|no-uniprot-update:|comment:mint - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/09 2017/08/10 rogid:T1QrlTN0bSeFp4VLvOxCyFReA2E11676 rogid:NYkPt/WNmKM3qAhhaufLCPkc/io9606 rigid:dx107ro7EvNRDvKXgeaO9PiQfwQ false flag tag:0-0 - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) intact:EBI-7355238 uniprotkb:Q92556-1 intact:MINT-1206864 intact:EBI-15668002|ensembl:ENSP00000312185|ensembl:ENSP00000394458|ensembl:ENSP00000406952 psi-mi:q85737_9hiv1(display_short)|psi-mi:EBI-7355238(display_long) psi-mi:q92556-1(display_long)|uniprotkb:ELMO1(gene name)|psi-mi:ELMO1(display_short)|uniprotkb:KIAA0281(gene name synonym)|uniprotkb:Protein ced-12 homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Janardhan et al. (2004) pubmed:14737186|doi:10.1371/journal.pbio.0020006|imex:IM-13619 taxid:11676(9hiv1)|taxid:11676(Human immunodeficiency virus 1) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16216879|imex:IM-13619-2|dip:DIP-102605E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q85737(uniprot-removed-ac) intact:EBI-346417(isoform-parent)|ensembl:ENSG00000155849(gene)|ensembl:ENST00000310758(transcript)|ensembl:ENST00000442504(transcript)|ensembl:ENST00000448602(transcript) psi-mi:"MI:0465"(dip) no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.|caution:This sequence has been withdrawn from Uniprot.|no-uniprot-update:|comment:mint - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/09 2017/08/10 rogid:T1QrlTN0bSeFp4VLvOxCyFReA2E11676 rogid:sW9Vj+Vej/oJb9qQxkbtIipDYXI9606 rigid:dx107ro7EvNRDvKXgeaO9PiQfwQ false flag tag:0-0 - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) intact:EBI-7355238 uniprotkb:Q92608 intact:MINT-1206864 intact:EBI-448771|uniprotkb:Q2M3I0|uniprotkb:Q96AK7|ensembl:ENSP00000429283 psi-mi:q85737_9hiv1(display_short)|psi-mi:EBI-7355238(display_long) psi-mi:dock2_human(display_long)|uniprotkb:DOCK2(gene name)|psi-mi:DOCK2(display_short)|uniprotkb:KIAA0209(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Janardhan et al. (2004) pubmed:14737186|doi:10.1371/journal.pbio.0020006|imex:IM-13619 taxid:11676(9hiv1)|taxid:11676(Human immunodeficiency virus 1) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16216879|imex:IM-13619-2|dip:DIP-102605E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q85737(uniprot-removed-ac) refseq:NP_004937.1|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001452(Src homology-3)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026791|interpro:IPR026799|interpro:IPR027007|interpro:IPR027357|interpro:IPR032376|interpro:IPR035892|interpro:IPR036028|interpro:IPR042455|interpro:IPR043161|interpro:IPR043162|go:"GO:0046633"(alpha-beta T cell proliferation)|mint:Q92608|rcsb pdb:2RQR|rcsb pdb:2YIN|rcsb pdb:3A98|rcsb pdb:3B13|rcsb pdb:6TGB|rcsb pdb:6TGC|reactome:R-HSA-164944|reactome:R-HSA-6798695|reactome:R-HSA-8980692|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-983231|ensembl:ENSG00000134516(gene)|go:"GO:0001766"(membrane raft polarization)|go:"GO:0001768"(establishment of T cell polarity)|go:"GO:0001771"(immunological synapse formation)|go:"GO:0002277"(myeloid dendritic cell activation involved in immune response)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006935"(chemotaxis)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0035580"(specific granule lumen)|go:"GO:0042608"(T cell receptor binding)|go:"GO:0044351"(macropinocytosis)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|ensembl:ENST00000520908(transcript)|dip:DIP-31791N psi-mi:"MI:0465"(dip) no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.|caution:This sequence has been withdrawn from Uniprot.|no-uniprot-update:|comment:mint - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/09 2017/08/10 rogid:T1QrlTN0bSeFp4VLvOxCyFReA2E11676 rogid:0GZlR6TI1N3mi2VBXsq3M6DJGpQ9606 rigid:dx107ro7EvNRDvKXgeaO9PiQfwQ false flag tag:0-0 - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) intact:EBI-7355238 uniprotkb:P15153 intact:MINT-1206864 intact:EBI-489652|ensembl:ENSP00000249071|uniprotkb:Q9UDJ4 psi-mi:q85737_9hiv1(display_short)|psi-mi:EBI-7355238(display_long) psi-mi:rac2_human(display_long)|uniprotkb:p21-Rac2(gene name synonym)|uniprotkb:Small G protein(gene name synonym)|uniprotkb:GX(gene name synonym)|uniprotkb:RAC2(gene name)|psi-mi:RAC2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Janardhan et al. (2004) pubmed:14737186|doi:10.1371/journal.pbio.0020006|imex:IM-13619 taxid:11676(9hiv1)|taxid:11676(Human immunodeficiency virus 1) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16217017|imex:IM-13619-7|dip:DIP-102605E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q85737(uniprot-removed-ac) go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0045453"(bone resorption)|go:"GO:0060263"(regulation of respiratory burst)|go:"GO:0060753"(regulation of mast cell chemotaxis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071593"(lymphocyte aggregation)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902622"(regulation of neutrophil migration)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P15153|rcsb pdb:1DS6|rcsb pdb:2W2T|rcsb pdb:2W2V|rcsb pdb:2W2X|reactome:R-HSA-114604|reactome:R-HSA-1222556|go:"GO:0043304"(regulation of mast cell degranulation)|ensembl:ENSG00000128340(gene)|ensembl:ENST00000249071(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007165"(signal transduction)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010310"(regulation of hydrogen peroxide metabolic process)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010810"(regulation of cell-substrate adhesion)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0005925"(focal adhesion)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0042129"(regulation of T cell proliferation)|go:"GO:0042995"(cell projection)|go:"GO:0043231"(intracellular membrane-bounded organelle)|reactome:R-HSA-1257604|refseq:NP_002863.1|reactome:R-HSA-2219530|reactome:R-HSA-4086400|reactome:R-HSA-5668599|reactome:R-HSA-6811558|reactome:R-HSA-9013404|dip:DIP-34291N psi-mi:"MI:0465"(dip) no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.|caution:This sequence has been withdrawn from Uniprot.|no-uniprot-update:|comment:mint - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/09 2017/08/10 rogid:T1QrlTN0bSeFp4VLvOxCyFReA2E11676 rogid:NYkPt/WNmKM3qAhhaufLCPkc/io9606 rigid:dx107ro7EvNRDvKXgeaO9PiQfwQ false flag tag:0-0 myc tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) intact:EBI-7355238 uniprotkb:Q92556-1 intact:MINT-1206864 intact:EBI-15668002|ensembl:ENSP00000312185|ensembl:ENSP00000394458|ensembl:ENSP00000406952 psi-mi:q85737_9hiv1(display_short)|psi-mi:EBI-7355238(display_long) psi-mi:q92556-1(display_long)|uniprotkb:ELMO1(gene name)|psi-mi:ELMO1(display_short)|uniprotkb:KIAA0281(gene name synonym)|uniprotkb:Protein ced-12 homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Janardhan et al. (2004) pubmed:14737186|doi:10.1371/journal.pbio.0020006|imex:IM-13619 taxid:11676(9hiv1)|taxid:11676(Human immunodeficiency virus 1) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16217017|imex:IM-13619-7|dip:DIP-102605E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q85737(uniprot-removed-ac) intact:EBI-346417(isoform-parent)|ensembl:ENSG00000155849(gene)|ensembl:ENST00000310758(transcript)|ensembl:ENST00000442504(transcript)|ensembl:ENST00000448602(transcript) psi-mi:"MI:0465"(dip) no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.|caution:This sequence has been withdrawn from Uniprot.|no-uniprot-update:|comment:mint - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/09 2017/08/10 rogid:T1QrlTN0bSeFp4VLvOxCyFReA2E11676 rogid:sW9Vj+Vej/oJb9qQxkbtIipDYXI9606 rigid:dx107ro7EvNRDvKXgeaO9PiQfwQ false flag tag:0-0 myc tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) intact:EBI-7355238 uniprotkb:Q92608 intact:MINT-1206864 intact:EBI-448771|uniprotkb:Q2M3I0|uniprotkb:Q96AK7|ensembl:ENSP00000429283 psi-mi:q85737_9hiv1(display_short)|psi-mi:EBI-7355238(display_long) psi-mi:dock2_human(display_long)|uniprotkb:DOCK2(gene name)|psi-mi:DOCK2(display_short)|uniprotkb:KIAA0209(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Janardhan et al. (2004) pubmed:14737186|doi:10.1371/journal.pbio.0020006|imex:IM-13619 taxid:11676(9hiv1)|taxid:11676(Human immunodeficiency virus 1) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16217017|imex:IM-13619-7|dip:DIP-102605E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q85737(uniprot-removed-ac) refseq:NP_004937.1|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001452(Src homology-3)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026791|interpro:IPR026799|interpro:IPR027007|interpro:IPR027357|interpro:IPR032376|interpro:IPR035892|interpro:IPR036028|interpro:IPR042455|interpro:IPR043161|interpro:IPR043162|go:"GO:0046633"(alpha-beta T cell proliferation)|mint:Q92608|rcsb pdb:2RQR|rcsb pdb:2YIN|rcsb pdb:3A98|rcsb pdb:3B13|rcsb pdb:6TGB|rcsb pdb:6TGC|reactome:R-HSA-164944|reactome:R-HSA-6798695|reactome:R-HSA-8980692|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-983231|ensembl:ENSG00000134516(gene)|go:"GO:0001766"(membrane raft polarization)|go:"GO:0001768"(establishment of T cell polarity)|go:"GO:0001771"(immunological synapse formation)|go:"GO:0002277"(myeloid dendritic cell activation involved in immune response)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006935"(chemotaxis)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0035580"(specific granule lumen)|go:"GO:0042608"(T cell receptor binding)|go:"GO:0044351"(macropinocytosis)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|ensembl:ENST00000520908(transcript)|dip:DIP-31791N psi-mi:"MI:0465"(dip) no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.|caution:This sequence has been withdrawn from Uniprot.|no-uniprot-update:|comment:mint - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/09 2017/08/10 rogid:T1QrlTN0bSeFp4VLvOxCyFReA2E11676 rogid:0GZlR6TI1N3mi2VBXsq3M6DJGpQ9606 rigid:dx107ro7EvNRDvKXgeaO9PiQfwQ false flag tag:0-0 his tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)