#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P69723 uniprotkb:Q9HC16 intact:EBI-15528966|uniprotkb:P03401 intact:EBI-717839|uniprotkb:Q45F02|uniprotkb:Q5TF77|uniprotkb:Q7Z2N1|uniprotkb:Q7Z2N4|uniprotkb:Q9H9H8|uniprotkb:B2RDR9|ensembl:ENSP00000385057 psi-mi:vif_hv1h2(display_long)|uniprotkb:SOR protein(gene name synonym)|uniprotkb:vif(gene name)|psi-mi:vif(display_short) psi-mi:abc3g_human(display_long)|uniprotkb:APOBEC-related cytidine deaminase(gene name synonym)|uniprotkb:APOBEC-related protein 9(gene name synonym)|uniprotkb:CEM-15(gene name synonym)|uniprotkb:APOBEC3G(gene name)|psi-mi:APOBEC3G(display_short)|uniprotkb:Deoxycytidine deaminase(gene name synonym)|uniprotkb:MDS019(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Marin et al. (2003) pubmed:14528301|doi:10.1038/nm946|imex:IM-24792 taxid:11706(hv1h2)|taxid:11706("Human immunodeficiency virus type 1 group M subtype B (isolate HXB2) (HIV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15529007|imex:IM-24792-1|dip:DIP-199723E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0016020"(membrane)|go:"GO:0019058"(viral life cycle)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0042802"(identical protein binding)|interpro:IPR000475("Retroviral Vif (Viral infectivity) protein")|refseq:NP_057851.1|reactome:R-HSA-162585|reactome:R-HSA-162588|reactome:R-HSA-162592|reactome:R-HSA-162594|reactome:R-HSA-164516|reactome:R-HSA-164525|reactome:R-HSA-164843|reactome:R-HSA-173107|reactome:R-HSA-175474|reactome:R-HSA-175567|reactome:R-HSA-177539|reactome:R-HSA-180585|reactome:R-HSA-180689|reactome:R-HSA-180910|dip:DIP-61318N refseq:NP_068594.1|ensembl:ENSG00000239713(gene)|ensembl:ENST00000407997(transcript)|go:"GO:0000932"(P-body)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003723"(RNA binding)|go:"GO:0004126"(cytidine deaminase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008829"(dCTP deaminase activity)|go:"GO:0009972"(cytidine deamination)|go:"GO:0010529"(negative regulation of transposition)|go:"GO:0016553"(base conversion or substitution editing)|go:"GO:0016554"(cytidine to uridine editing)|go:"GO:0030895"(apolipoprotein B mRNA editing enzyme complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0047844"(deoxycytidine deaminase activity)|go:"GO:0048525"(negative regulation of viral process)|go:"GO:0051607"(defense response to virus)|go:"GO:0070383"(DNA cytosine deamination)|go:"GO:0080111"(DNA demethylation)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR002125(CMP/dCMP deaminase, zinc-binding)|interpro:IPR016192(APOBEC/CMP deaminase, zinc-binding)|interpro:IPR016193(Cytidine deaminase-like)|interpro:IPR040551|rcsb pdb:2KBO|rcsb pdb:2KEM|rcsb pdb:3E1U|rcsb pdb:3IQS|rcsb pdb:3IR2|rcsb pdb:3V4J|rcsb pdb:3V4K|rcsb pdb:4ROV|rcsb pdb:4ROW|rcsb pdb:5ZVA|rcsb pdb:5ZVB|rcsb pdb:6BUX|rcsb pdb:6BWY|rcsb pdb:6K3J|rcsb pdb:6K3K|reactome:R-HSA-180585|reactome:R-HSA-180689|rcsb pdb:2JYW|dip:DIP-37519N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/04 2017/08/10 rogid:zZCNRTNfMY5QKW+P8XLzdnYg3EA11706 rogid:o6JWyu1Is1J9e0CiLKAudHeFC4Y9606 rigid:wlMsxE6vTbdaLpT6BA0ey8xhwU8 false necessary binding region:12-23|necessary binding region:43-59|necessary binding region:73-87|necessary binding region:97-112|necessary binding region:111-128 myc tag:c-c - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P69723 uniprotkb:Q9HC16 intact:EBI-15528966|uniprotkb:P03401 intact:EBI-717839|uniprotkb:Q45F02|uniprotkb:Q5TF77|uniprotkb:Q7Z2N1|uniprotkb:Q7Z2N4|uniprotkb:Q9H9H8|uniprotkb:B2RDR9|ensembl:ENSP00000385057 psi-mi:vif_hv1h2(display_long)|uniprotkb:SOR protein(gene name synonym)|uniprotkb:vif(gene name)|psi-mi:vif(display_short) psi-mi:abc3g_human(display_long)|uniprotkb:APOBEC-related cytidine deaminase(gene name synonym)|uniprotkb:APOBEC-related protein 9(gene name synonym)|uniprotkb:CEM-15(gene name synonym)|uniprotkb:APOBEC3G(gene name)|psi-mi:APOBEC3G(display_short)|uniprotkb:Deoxycytidine deaminase(gene name synonym)|uniprotkb:MDS019(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Marin et al. (2003) pubmed:14528301|doi:10.1038/nm946|imex:IM-24792 taxid:11706(hv1h2)|taxid:11706("Human immunodeficiency virus type 1 group M subtype B (isolate HXB2) (HIV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15529036|imex:IM-24792-2|dip:DIP-199723E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0016020"(membrane)|go:"GO:0019058"(viral life cycle)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0042802"(identical protein binding)|interpro:IPR000475("Retroviral Vif (Viral infectivity) protein")|refseq:NP_057851.1|reactome:R-HSA-162585|reactome:R-HSA-162588|reactome:R-HSA-162592|reactome:R-HSA-162594|reactome:R-HSA-164516|reactome:R-HSA-164525|reactome:R-HSA-164843|reactome:R-HSA-173107|reactome:R-HSA-175474|reactome:R-HSA-175567|reactome:R-HSA-177539|reactome:R-HSA-180585|reactome:R-HSA-180689|reactome:R-HSA-180910|dip:DIP-61318N refseq:NP_068594.1|ensembl:ENSG00000239713(gene)|ensembl:ENST00000407997(transcript)|go:"GO:0000932"(P-body)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003723"(RNA binding)|go:"GO:0004126"(cytidine deaminase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008829"(dCTP deaminase activity)|go:"GO:0009972"(cytidine deamination)|go:"GO:0010529"(negative regulation of transposition)|go:"GO:0016553"(base conversion or substitution editing)|go:"GO:0016554"(cytidine to uridine editing)|go:"GO:0030895"(apolipoprotein B mRNA editing enzyme complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0047844"(deoxycytidine deaminase activity)|go:"GO:0048525"(negative regulation of viral process)|go:"GO:0051607"(defense response to virus)|go:"GO:0070383"(DNA cytosine deamination)|go:"GO:0080111"(DNA demethylation)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR002125(CMP/dCMP deaminase, zinc-binding)|interpro:IPR016192(APOBEC/CMP deaminase, zinc-binding)|interpro:IPR016193(Cytidine deaminase-like)|interpro:IPR040551|rcsb pdb:2KBO|rcsb pdb:2KEM|rcsb pdb:3E1U|rcsb pdb:3IQS|rcsb pdb:3IR2|rcsb pdb:3V4J|rcsb pdb:3V4K|rcsb pdb:4ROV|rcsb pdb:4ROW|rcsb pdb:5ZVA|rcsb pdb:5ZVB|rcsb pdb:6BUX|rcsb pdb:6BWY|rcsb pdb:6K3J|rcsb pdb:6K3K|reactome:R-HSA-180585|reactome:R-HSA-180689|rcsb pdb:2JYW|dip:DIP-37519N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/04 2017/08/10 rogid:zZCNRTNfMY5QKW+P8XLzdnYg3EA11706 rogid:o6JWyu1Is1J9e0CiLKAudHeFC4Y9606 rigid:wlMsxE6vTbdaLpT6BA0ey8xhwU8 false - myc tag:c-c - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)