#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P09546 uniprotkb:P09546 intact:EBI-369718|uniprotkb:P78296|ensemblbacteria:AAC74099|ensemblbacteria:BAA35791 intact:EBI-369718|uniprotkb:P78296|ensemblbacteria:AAC74099|ensemblbacteria:BAA35791 psi-mi:puta_ecoli(display_long)|uniprotkb:putA(gene name)|psi-mi:putA(display_short)|uniprotkb:poaA(gene name synonym)|uniprotkb:b1014(locus name)|uniprotkb:JW0999(locus name) psi-mi:puta_ecoli(display_long)|uniprotkb:putA(gene name)|psi-mi:putA(display_short)|uniprotkb:poaA(gene name synonym)|uniprotkb:b1014(locus name)|uniprotkb:JW0999(locus name) psi-mi:"MI:0114"(x-ray crystallography) Lee et al. (2003) pubmed:12514740|doi:10.1038/nsb885|imex:IM-23313 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15528837|imex:IM-23313-1|dip:DIP-18600E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4O8A|refseq:WP_001326840.1|ensemblbacteria:AAC74099(transcript)|ensemblbacteria:b1014(gene)|ensemblbacteria:BAA35791(gene)|ensemblbacteria:BAA35791(transcript)|go:"GO:0000986"|go:"GO:0001217"(DNA-binding transcription repressor activity)|go:"GO:0003677"(DNA binding)|go:"GO:0003842"(1-pyrroline-5-carboxylate dehydrogenase activity)|go:"GO:0004657"(proline dehydrogenase activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006561"(proline biosynthetic process)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010133"(proline catabolic process to glutamate)|refseq:NP_415534.1|interpro:IPR013321(Arc-type ribbon-helix-helix)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR016160(Aldehyde dehydrogenase, conserved site)|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|interpro:IPR024082|interpro:IPR024089|interpro:IPR024090|interpro:IPR025703|interpro:IPR029041|interpro:IPR029510|interpro:IPR041349|rcsb pdb:1TIW|rcsb pdb:1TJ0|rcsb pdb:1TJ1|rcsb pdb:1TJ2|rcsb pdb:2AY0|rcsb pdb:2FZM|rcsb pdb:2FZN|rcsb pdb:2GPE|rcsb pdb:2RBF|rcsb pdb:3E2Q|rcsb pdb:3E2R|rcsb pdb:3E2S|rcsb pdb:3ITG|rcsb pdb:4JNY|rcsb pdb:4JNZ|go:"GO:0016620"(oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR002872(Proline dehydrogenase)|interpro:IPR005933(Delta-1-pyrroline-5-carboxylate dehydrogenase 3)|interpro:IPR010985(Ribbon-helix-helix)|mint:P09546|dip:DIP-10620N rcsb pdb:4O8A|refseq:WP_001326840.1|ensemblbacteria:AAC74099(transcript)|ensemblbacteria:b1014(gene)|ensemblbacteria:BAA35791(gene)|ensemblbacteria:BAA35791(transcript)|go:"GO:0000986"|go:"GO:0001217"(DNA-binding transcription repressor activity)|go:"GO:0003677"(DNA binding)|go:"GO:0003842"(1-pyrroline-5-carboxylate dehydrogenase activity)|go:"GO:0004657"(proline dehydrogenase activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006561"(proline biosynthetic process)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010133"(proline catabolic process to glutamate)|refseq:NP_415534.1|interpro:IPR013321(Arc-type ribbon-helix-helix)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR016160(Aldehyde dehydrogenase, conserved site)|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|interpro:IPR024082|interpro:IPR024089|interpro:IPR024090|interpro:IPR025703|interpro:IPR029041|interpro:IPR029510|interpro:IPR041349|rcsb pdb:1TIW|rcsb pdb:1TJ0|rcsb pdb:1TJ1|rcsb pdb:1TJ2|rcsb pdb:2AY0|rcsb pdb:2FZM|rcsb pdb:2FZN|rcsb pdb:2GPE|rcsb pdb:2RBF|rcsb pdb:3E2Q|rcsb pdb:3E2R|rcsb pdb:3E2S|rcsb pdb:3ITG|rcsb pdb:4JNY|rcsb pdb:4JNZ|go:"GO:0016620"(oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR002872(Proline dehydrogenase)|interpro:IPR005933(Delta-1-pyrroline-5-carboxylate dehydrogenase 3)|interpro:IPR010985(Ribbon-helix-helix)|mint:P09546|dip:DIP-10620N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/04 2017/08/10 rogid:0NuRAppRwkFU+FZWfeXx7OlC2BU83333 rogid:0NuRAppRwkFU+FZWfeXx7OlC2BU83333 rigid:r2qVFrrYV/AgkqmYNJAdBxQBvU4 false sufficient binding region:1-669 sufficient binding region:1-669 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)