#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P04387 uniprotkb:P13045 intact:EBI-2061197|uniprotkb:D6VZC4|ensemblfungi:YML051W intact:EBI-7282|uniprotkb:D6VRZ6|ensemblfungi:YDR009W psi-mi:gal80_yeast(display_long)|uniprotkb:GAL80(gene name)|psi-mi:GAL80(display_short)|uniprotkb:YM9958.12(orf name)|uniprotkb:YM9827.01(orf name)|uniprotkb:YML051W(locus name) psi-mi:gal3_yeast(display_long)|uniprotkb:YD8119.14(orf name)|uniprotkb:YDR009W(locus name)|uniprotkb:GAL3(gene name)|psi-mi:GAL3(display_short) psi-mi:"MI:0605"(enzymatic footprinting) Timson et al. (2002) pubmed:11964151|imex:IM-25692 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-13916562|imex:IM-25692-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013661.1|sgd:S000004515|dip:DIP-594N|mint:P04387|ensemblfungi:YML051W(gene)|ensemblfungi:YML051W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006012"(galactose metabolic process)|go:"GO:0019210"(kinase inhibitor activity)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR000683(Oxidoreductase, N-terminal)|interpro:IPR036291|rcsb pdb:3BTS|rcsb pdb:3BTU|rcsb pdb:3BTV|rcsb pdb:3V2U refseq:NP_010292.1|sgd:S000002416|mint:P13045|dip:DIP-5725N|ensemblfungi:YDR009W(gene)|ensemblfungi:YDR009W_mRNA(transcript)|go:"GO:0000435"(positive regulation of transcription from RNA polymerase II promoter by galactose)|go:"GO:0004335"(galactokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006012"(galactose metabolic process)|go:"GO:0045185"(maintenance of protein location)|interpro:IPR000705(Galactokinase)|interpro:IPR006204(GHMP kinase)|interpro:IPR006206(Mevalonate and galactokinase)|interpro:IPR013750(GHMP kinase, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR019539|interpro:IPR019741|interpro:IPR020568|interpro:IPR036554|rcsb pdb:3V2U|rcsb pdb:3V5R - crc64:1492473684F3894C crc64:5852028EBDDC0F3B comment:Interaction requires the presence of galactose and ATP or ADP|figure legend:Fig. 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/02/17 2017/02/17 rogid:6ryfff/vlV8NQ3Fk1U8RWaUWkxE559292 rogid:EtOtuZODEOlw/PgA2I0MimDXYsU559292 rigid:RPqavQmBFQNeKET25pY1c3p+S2A false his tag:?-? his tag:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P04387 uniprotkb:P04385 intact:EBI-2061197|uniprotkb:D6VZC4|ensemblfungi:YML051W intact:EBI-7272|uniprotkb:D6VQ22|ensemblfungi:YBR020W psi-mi:gal80_yeast(display_long)|uniprotkb:GAL80(gene name)|psi-mi:GAL80(display_short)|uniprotkb:YM9958.12(orf name)|uniprotkb:YM9827.01(orf name)|uniprotkb:YML051W(locus name) psi-mi:gal1_yeast(display_long)|uniprotkb:GAL1(gene name)|psi-mi:GAL1(display_short)|uniprotkb:YBR020W(locus name)|uniprotkb:YBR0302(orf name)|uniprotkb:Galactose kinase(gene name synonym) psi-mi:"MI:0605"(enzymatic footprinting) Timson et al. (2002) pubmed:11964151|imex:IM-25692 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-13916571|imex:IM-25692-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013661.1|sgd:S000004515|dip:DIP-594N|mint:P04387|ensemblfungi:YML051W(gene)|ensemblfungi:YML051W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006012"(galactose metabolic process)|go:"GO:0019210"(kinase inhibitor activity)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR000683(Oxidoreductase, N-terminal)|interpro:IPR036291|rcsb pdb:3BTS|rcsb pdb:3BTU|rcsb pdb:3BTV|rcsb pdb:3V2U refseq:NP_009576.1|sgd:S000000224|dip:DIP-2333N|ensemblfungi:YBR020W(gene)|ensemblfungi:YBR020W_mRNA(transcript)|go:"GO:0000411"(positive regulation of transcription by galactose)|go:"GO:0004335"(galactokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006012"(galactose metabolic process)|go:"GO:0033499"(galactose catabolic process via UDP-galactose)|go:"GO:0046835"(carbohydrate phosphorylation)|interpro:IPR000705(Galactokinase)|interpro:IPR006203(GHMP kinase, ATP-binding, conserved site)|interpro:IPR006204(GHMP kinase)|interpro:IPR006206(Mevalonate and galactokinase)|interpro:IPR013750(GHMP kinase, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR019539|interpro:IPR019741|interpro:IPR020568|interpro:IPR036554|rcsb pdb:2AJ4 - crc64:1492473684F3894C crc64:1DA31A1915C19107 comment:Interaction requires the presence of galactose and ATP|figure legend:Fig. 4A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/02/17 2017/02/17 rogid:6ryfff/vlV8NQ3Fk1U8RWaUWkxE559292 rogid:4xdu9k+Ox0Nd0VymlexeGa6GDIQ559292 rigid:sYZksnvPVGbNUxoTE6Wi9+rb28k false his tag:?-? his tag:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P04387 uniprotkb:P04385 intact:EBI-2061197|uniprotkb:D6VZC4|ensemblfungi:YML051W intact:EBI-7272|uniprotkb:D6VQ22|ensemblfungi:YBR020W psi-mi:gal80_yeast(display_long)|uniprotkb:GAL80(gene name)|psi-mi:GAL80(display_short)|uniprotkb:YM9958.12(orf name)|uniprotkb:YM9827.01(orf name)|uniprotkb:YML051W(locus name) psi-mi:gal1_yeast(display_long)|uniprotkb:GAL1(gene name)|psi-mi:GAL1(display_short)|uniprotkb:YBR020W(locus name)|uniprotkb:YBR0302(orf name)|uniprotkb:Galactose kinase(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Timson et al. (2002) pubmed:11964151|imex:IM-25692 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-13916594|imex:IM-25692-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013661.1|sgd:S000004515|dip:DIP-594N|mint:P04387|ensemblfungi:YML051W(gene)|ensemblfungi:YML051W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006012"(galactose metabolic process)|go:"GO:0019210"(kinase inhibitor activity)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR000683(Oxidoreductase, N-terminal)|interpro:IPR036291|rcsb pdb:3BTS|rcsb pdb:3BTU|rcsb pdb:3BTV|rcsb pdb:3V2U refseq:NP_009576.1|sgd:S000000224|dip:DIP-2333N|ensemblfungi:YBR020W(gene)|ensemblfungi:YBR020W_mRNA(transcript)|go:"GO:0000411"(positive regulation of transcription by galactose)|go:"GO:0004335"(galactokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006012"(galactose metabolic process)|go:"GO:0033499"(galactose catabolic process via UDP-galactose)|go:"GO:0046835"(carbohydrate phosphorylation)|interpro:IPR000705(Galactokinase)|interpro:IPR006203(GHMP kinase, ATP-binding, conserved site)|interpro:IPR006204(GHMP kinase)|interpro:IPR006206(Mevalonate and galactokinase)|interpro:IPR013750(GHMP kinase, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR019539|interpro:IPR019741|interpro:IPR020568|interpro:IPR036554|rcsb pdb:2AJ4 - crc64:1492473684F3894C crc64:1DA31A1915C19107 comment:Interaction requires the presence of galactose and ATP|figure legend:Fig. 4B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/02/17 2017/02/17 rogid:6ryfff/vlV8NQ3Fk1U8RWaUWkxE559292 rogid:4xdu9k+Ox0Nd0VymlexeGa6GDIQ559292 rigid:sYZksnvPVGbNUxoTE6Wi9+rb28k false his tag:?-? his tag:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P04387 uniprotkb:P13045 intact:EBI-2061197|uniprotkb:D6VZC4|ensemblfungi:YML051W intact:EBI-7282|uniprotkb:D6VRZ6|ensemblfungi:YDR009W psi-mi:gal80_yeast(display_long)|uniprotkb:GAL80(gene name)|psi-mi:GAL80(display_short)|uniprotkb:YM9958.12(orf name)|uniprotkb:YM9827.01(orf name)|uniprotkb:YML051W(locus name) psi-mi:gal3_yeast(display_long)|uniprotkb:YD8119.14(orf name)|uniprotkb:YDR009W(locus name)|uniprotkb:GAL3(gene name)|psi-mi:GAL3(display_short) psi-mi:"MI:0071"(molecular sieving) Timson et al. (2002) pubmed:11964151|imex:IM-25692 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-13916585|imex:IM-25692-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013661.1|sgd:S000004515|dip:DIP-594N|mint:P04387|ensemblfungi:YML051W(gene)|ensemblfungi:YML051W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006012"(galactose metabolic process)|go:"GO:0019210"(kinase inhibitor activity)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR000683(Oxidoreductase, N-terminal)|interpro:IPR036291|rcsb pdb:3BTS|rcsb pdb:3BTU|rcsb pdb:3BTV|rcsb pdb:3V2U refseq:NP_010292.1|sgd:S000002416|mint:P13045|dip:DIP-5725N|ensemblfungi:YDR009W(gene)|ensemblfungi:YDR009W_mRNA(transcript)|go:"GO:0000435"(positive regulation of transcription from RNA polymerase II promoter by galactose)|go:"GO:0004335"(galactokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006012"(galactose metabolic process)|go:"GO:0045185"(maintenance of protein location)|interpro:IPR000705(Galactokinase)|interpro:IPR006204(GHMP kinase)|interpro:IPR006206(Mevalonate and galactokinase)|interpro:IPR013750(GHMP kinase, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR019539|interpro:IPR019741|interpro:IPR020568|interpro:IPR036554|rcsb pdb:3V2U|rcsb pdb:3V5R - crc64:1492473684F3894C crc64:5852028EBDDC0F3B comment:Interaction requires the presence of galactose and ATP. Molecular weight 91 kDa,|figure legend:Fig. 2B, 3A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/02/17 2017/02/17 rogid:6ryfff/vlV8NQ3Fk1U8RWaUWkxE559292 rogid:EtOtuZODEOlw/PgA2I0MimDXYsU559292 rigid:RPqavQmBFQNeKET25pY1c3p+S2A false mutation decreasing interaction strength:351-351|his tag:?-? his tag:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P04387 uniprotkb:P04386 intact:EBI-2061197|uniprotkb:D6VZC4|ensemblfungi:YML051W intact:EBI-4407660|uniprotkb:D6W3C3|ensemblfungi:YPL248C psi-mi:gal80_yeast(display_long)|uniprotkb:GAL80(gene name)|psi-mi:GAL80(display_short)|uniprotkb:YM9958.12(orf name)|uniprotkb:YM9827.01(orf name)|uniprotkb:YML051W(locus name) psi-mi:gal4_yeast(display_long)|uniprotkb:GAL4(gene name)|psi-mi:GAL4(display_short)|uniprotkb:YPL248C(locus name) psi-mi:"MI:0030"(cross-linking study) Timson et al. (2002) pubmed:11964151|imex:IM-25692 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-13916649|imex:IM-25692-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013661.1|sgd:S000004515|dip:DIP-594N|mint:P04387|ensemblfungi:YML051W(gene)|ensemblfungi:YML051W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006012"(galactose metabolic process)|go:"GO:0019210"(kinase inhibitor activity)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR000683(Oxidoreductase, N-terminal)|interpro:IPR036291|rcsb pdb:3BTS|rcsb pdb:3BTU|rcsb pdb:3BTV|rcsb pdb:3V2U refseq:NP_015076.1|sgd:S000006169|mint:P04386|dip:DIP-593N|ensemblfungi:YPL248C(gene)|ensemblfungi:YPL248C_mRNA(transcript)|go:"GO:0000435"(positive regulation of transcription from RNA polymerase II promoter by galactose)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006012"(galactose metabolic process)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR001138(Fungal transcriptional regulatory protein, N-terminal)|interpro:IPR005600(Gal4-like dimerisation domain)|interpro:IPR007219(Fungal specific transcription factor)|interpro:IPR036864|rcsb pdb:1AW6|rcsb pdb:1D66|rcsb pdb:1HBW|rcsb pdb:3BTS|rcsb pdb:3COQ - crc64:1492473684F3894C crc64:29D7FF68B0B05880 comment:Interaction requires the presence of galactose and ATP|figure legend:Fig. 3B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/02/17 2017/02/17 rogid:6ryfff/vlV8NQ3Fk1U8RWaUWkxE559292 rogid:3bV9oJGeVBncvgN7655e/XjQzOo559292 rigid:o+uSJc/l2BmpuP3Ik6E353rv+F8 false his tag:?-?|mutation with no effect:351-351 his tag:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)