#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P63104	uniprotkb:O43524	intact:EBI-347088|ensembl:ENSP00000309503|ensembl:ENSP00000379281|ensembl:ENSP00000379283|ensembl:ENSP00000379286|ensembl:ENSP00000379287|ensembl:ENSP00000379288|ensembl:ENSP00000395114|ensembl:ENSP00000398599|uniprotkb:P29213|uniprotkb:P29312|uniprotkb:Q32P43|uniprotkb:Q5XJ08|uniprotkb:Q6GPI2|uniprotkb:Q6IN74|uniprotkb:Q6NUR9|uniprotkb:Q6P3U9|uniprotkb:Q86V33|uniprotkb:A8K1N0|uniprotkb:B7Z465	intact:EBI-1644164|uniprotkb:Q9BZ04|uniprotkb:O15171|uniprotkb:Q5T2I7|uniprotkb:E1P5E6|uniprotkb:B4DVZ6|ensembl:ENSP00000339527|ensembl:ENSP00000385824	psi-mi:1433z_human(display_long)|uniprotkb:YWHAZ(gene name)|psi-mi:YWHAZ(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym)	psi-mi:foxo3_human(display_long)|uniprotkb:FOXO3(gene name)|psi-mi:FOXO3(display_short)|uniprotkb:FKHRL1(gene name synonym)|uniprotkb:FOXO3A(gene name synonym)|uniprotkb:Forkhead in rhabdomyosarcoma-like 1(gene name synonym)|uniprotkb:AF6q21 protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Brunet et al. (2002)	pubmed:11864996	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1264"(NTNU)	intact:EBI-15098123	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000164924(gene)|ensembl:ENST00000353245(transcript)|ensembl:ENST00000395951(transcript)|ensembl:ENST00000395953(transcript)|ensembl:ENST00000395956(transcript)|ensembl:ENST00000395957(transcript)|ensembl:ENST00000395958(transcript)|ensembl:ENST00000419477(transcript)|ensembl:ENST00000457309(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0003016"(respiratory system process)|go:"GO:0003723"(RNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006605"(protein targeting)|go:"GO:0007165"(signal transduction)|go:"GO:0008039"(synaptic target recognition)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030324"(lung development)|go:"GO:0031982"(vesicle)|go:"GO:0035148"(tube formation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0072562"(blood microparticle)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|rcsb pdb:1IB1|rcsb pdb:1QJA|rcsb pdb:1QJB|rcsb pdb:2C1J|rcsb pdb:2C1N|rcsb pdb:2O02|rcsb pdb:2WH0|rcsb pdb:3CU8|mint:P63104|rcsb pdb:3NKX|rcsb pdb:3RDH|rcsb pdb:4BG6|rcsb pdb:4FJ3|rcsb pdb:4HKC|rcsb pdb:4IHL|rcsb pdb:4N7G|rcsb pdb:4N7Y|rcsb pdb:4N84|rcsb pdb:4WRQ|rcsb pdb:4ZDR|rcsb pdb:5D2D|rcsb pdb:5D3F|rcsb pdb:5EWZ|rcsb pdb:5EXA|rcsb pdb:5JM4|rcsb pdb:5M35|rcsb pdb:5M36|rcsb pdb:5M37|rcsb pdb:5NAS|rcsb pdb:5ULO|rcsb pdb:5WXN|rcsb pdb:5XY9|rcsb pdb:6EF5|rcsb pdb:6EJL|rcsb pdb:6EWW|rcsb pdb:6F08|rcsb pdb:6F09|rcsb pdb:6FN9|rcsb pdb:5J31|rcsb pdb:6FNA|rcsb pdb:6FNB|rcsb pdb:6FNC|rcsb pdb:6Q0K|rcsb pdb:6RLZ|rcsb pdb:6U2H|rcsb pdb:6XAG|rcsb pdb:6YMO|rcsb pdb:6YO8|rcsb pdb:6ZFD|rcsb pdb:6ZFG|rcsb pdb:7D8H|rcsb pdb:7D8P|rcsb pdb:7D9V|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-3769402|reactome:R-HSA-392517|reactome:R-HSA-430116|reactome:R-HSA-450604|reactome:R-HSA-512988|reactome:R-HSA-5625740|rcsb pdb:6YOS|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-9013700|reactome:R-HSA-9604323|reactome:R-HSA-9614399|refseq:NP_001129171.1|refseq:NP_001129172.1|refseq:NP_001129173.1|refseq:NP_001129174.1|refseq:NP_003397.1|refseq:NP_663723.1|refseq:XP_005251118.1|refseq:XP_005251120.1|refseq:XP_016869299.1|refseq:XP_016869300.1|dip:DIP-563N	refseq:XP_011533930.1|refseq:XP_011533931.1|refseq:XP_005266925.1|refseq:NP_001446.1|refseq:NP_963853.1|refseq:XP_016866075.1|dip:DIP-29723N|ensembl:ENSG00000118689(gene)|ensembl:ENST00000343882(transcript)|ensembl:ENST00000406360(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001542"(ovulation from ovarian follicle)|go:"GO:0001544"(initiation of primordial ovarian follicle growth)|go:"GO:0001547"(antral ovarian follicle growth)|go:"GO:0001556"(oocyte maturation)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006390"(mitochondrial transcription)|go:"GO:0006417"(regulation of translation)|go:"GO:0007568"(aging)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0014737"(positive regulation of muscle atrophy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034246"(mitochondrial transcription factor activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042493"|go:"GO:0042594"(response to starvation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0070542"(response to fatty acid)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071386"(cellular response to corticosterone stimulus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071548"(response to dexamethasone)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:0097192"(extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:1901300"(positive regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903428"(positive regulation of reactive oxygen species biosynthetic process)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:1990785"(response to water-immersion restraint stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000177"(regulation of neural precursor cell proliferation)|go:"GO:2000353"(positive regulation of endothelial cell apoptotic process)|interpro:IPR001766(Fork head transcription factor)|interpro:IPR030456|interpro:IPR032067|interpro:IPR032068|interpro:IPR036388|interpro:IPR036390|rcsb pdb:2K86|rcsb pdb:2LQH|rcsb pdb:2LQI|rcsb pdb:2UZK|rcsb pdb:6MNL|reactome:R-HSA-1181150|reactome:R-HSA-198693|reactome:R-HSA-5674400|reactome:R-HSA-5687128|reactome:R-HSA-6785807|reactome:R-HSA-8862803|reactome:R-HSA-8952158|reactome:R-HSA-9607240|reactome:R-HSA-9614399|reactome:R-HSA-9614657|reactome:R-HSA-9615017|reactome:R-HSA-9617629|reactome:R-HSA-9617828|reactome:R-HSA-9634638	-	-	crc64:E5B4E830665A9982	figure legend:Figure 5E|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2017/06/05	2017/06/05	rogid:70ZqFn0J1A7ykybulqWg4Ll21+U9606	rogid:kzNUkcFagA9f+Zhr7tZokroPzQQ9606	rigid:4DAHgucsA193eQongfXSZOQ9yik	false	tag:?-?	mutation disrupting interaction:32-32,253-253,315-315|ha tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)