#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q99972	uniprotkb:P10916	intact:EBI-11692272|uniprotkb:B2RD84|uniprotkb:O00620|uniprotkb:Q7Z6Q9|ensembl:ENSP00000037502	intact:EBI-725770|uniprotkb:Q16123|ensembl:ENSP00000228841	psi-mi:myoc_human(display_long)|uniprotkb:Myocilin 55 kDa subunit(gene name synonym)|uniprotkb:Trabecular meshwork-induced glucocorticoid response protein(gene name synonym)|uniprotkb:MYOC(gene name)|psi-mi:MYOC(display_short)|uniprotkb:GLC1A(gene name synonym)|uniprotkb:TIGR(gene name synonym)	psi-mi:mlrv_human(display_long)|uniprotkb:MYL2(gene name)|psi-mi:MYL2(display_short)|uniprotkb:Cardiac myosin light chain 2(gene name synonym)|uniprotkb:MLC2(gene name synonym)|uniprotkb:Myosin light chain 2, slow skeletal/ventricular muscle isoform(gene name synonym)|uniprotkb:Ventricular myosin light chain 2(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Wentz-Hunter et al. (2002)	pubmed:11773029|imex:IM-25654	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-13635625|imex:IM-25654-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000252.1|ensembl:ENSG00000034971(gene)|ensembl:ENST00000037502(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0001968"(fibronectin binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005929"(cilium)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014734"(skeletal muscle hypertrophy)|go:"GO:0022011"(myelination in peripheral nervous system)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031175"(neuron projection development)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032027"(myosin light chain binding)|go:"GO:0033268"(node of Ranvier)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0038031"(non-canonical Wnt signaling pathway via JNK cascade)|go:"GO:0038133"(ERBB2-ERBB3 signaling pathway)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0045162"(clustering of voltage-gated sodium channels)|go:"GO:0046872"(metal ion binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051901"(positive regulation of mitochondrial depolarization)|go:"GO:0060348"(bone development)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|interpro:IPR003112(Olfactomedin-like)|interpro:IPR031213|rcsb pdb:4WXQ|rcsb pdb:4WXS|rcsb pdb:4WXU|rcsb pdb:6OU0|rcsb pdb:6OU1|rcsb pdb:6OU2|rcsb pdb:6OU3|rcsb pdb:6PKD|rcsb pdb:6PKE|rcsb pdb:6PKF	refseq:NP_000423.2|ensembl:ENSG00000111245(gene)|ensembl:ENST00000228841(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006942"(regulation of striated muscle contraction)|go:"GO:0007507"(heart development)|go:"GO:0016459"(myosin complex)|go:"GO:0030016"(myofibril)|go:"GO:0030017"(sarcomere)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031672"(A band)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060047"(heart contraction)|go:"GO:0097512"(cardiac myofibril)|go:"GO:0098735"(positive regulation of the force of heart contraction)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|rcsb pdb:5TBY|reactome:R-HSA-390522|go:"GO:0008307"(structural constituent of muscle)	-	comment:Full length MYOC as bait did not give interacting clones	-	figure legend:no figure|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/01/23	2017/01/23	rogid:pku0+OsoErOjbVJK0Q+k6ToyDfw9606	rogid:n2YsPUkQrzvaH0/De4h+/K5Q8rE9606	rigid:JAZMQv1eExApUcIbn4q3wW0QJZo	false	sufficient binding region:64-504	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q99972	uniprotkb:Q99972	intact:EBI-11692272|uniprotkb:B2RD84|uniprotkb:O00620|uniprotkb:Q7Z6Q9|ensembl:ENSP00000037502	intact:EBI-11692272|uniprotkb:B2RD84|uniprotkb:O00620|uniprotkb:Q7Z6Q9|ensembl:ENSP00000037502	psi-mi:myoc_human(display_long)|uniprotkb:Myocilin 55 kDa subunit(gene name synonym)|uniprotkb:Trabecular meshwork-induced glucocorticoid response protein(gene name synonym)|uniprotkb:MYOC(gene name)|psi-mi:MYOC(display_short)|uniprotkb:GLC1A(gene name synonym)|uniprotkb:TIGR(gene name synonym)	psi-mi:myoc_human(display_long)|uniprotkb:Myocilin 55 kDa subunit(gene name synonym)|uniprotkb:Trabecular meshwork-induced glucocorticoid response protein(gene name synonym)|uniprotkb:MYOC(gene name)|psi-mi:MYOC(display_short)|uniprotkb:GLC1A(gene name synonym)|uniprotkb:TIGR(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Wentz-Hunter et al. (2002)	pubmed:11773029|imex:IM-25654	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-13635632|imex:IM-25654-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000252.1|ensembl:ENSG00000034971(gene)|ensembl:ENST00000037502(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0001968"(fibronectin binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005929"(cilium)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014734"(skeletal muscle hypertrophy)|go:"GO:0022011"(myelination in peripheral nervous system)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031175"(neuron projection development)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032027"(myosin light chain binding)|go:"GO:0033268"(node of Ranvier)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0038031"(non-canonical Wnt signaling pathway via JNK cascade)|go:"GO:0038133"(ERBB2-ERBB3 signaling pathway)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0045162"(clustering of voltage-gated sodium channels)|go:"GO:0046872"(metal ion binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051901"(positive regulation of mitochondrial depolarization)|go:"GO:0060348"(bone development)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|interpro:IPR003112(Olfactomedin-like)|interpro:IPR031213|rcsb pdb:4WXQ|rcsb pdb:4WXS|rcsb pdb:4WXU|rcsb pdb:6OU0|rcsb pdb:6OU1|rcsb pdb:6OU2|rcsb pdb:6OU3|rcsb pdb:6PKD|rcsb pdb:6PKE|rcsb pdb:6PKF	refseq:NP_000252.1|ensembl:ENSG00000034971(gene)|ensembl:ENST00000037502(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0001968"(fibronectin binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005929"(cilium)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014734"(skeletal muscle hypertrophy)|go:"GO:0022011"(myelination in peripheral nervous system)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031175"(neuron projection development)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032027"(myosin light chain binding)|go:"GO:0033268"(node of Ranvier)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0038031"(non-canonical Wnt signaling pathway via JNK cascade)|go:"GO:0038133"(ERBB2-ERBB3 signaling pathway)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0045162"(clustering of voltage-gated sodium channels)|go:"GO:0046872"(metal ion binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051901"(positive regulation of mitochondrial depolarization)|go:"GO:0060348"(bone development)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|interpro:IPR003112(Olfactomedin-like)|interpro:IPR031213|rcsb pdb:4WXQ|rcsb pdb:4WXS|rcsb pdb:4WXU|rcsb pdb:6OU0|rcsb pdb:6OU1|rcsb pdb:6OU2|rcsb pdb:6OU3|rcsb pdb:6PKD|rcsb pdb:6PKE|rcsb pdb:6PKF	-	-	comment:Full length MYOC as bait did not give interacting clones	figure legend:no figure|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/01/23	2017/01/23	rogid:pku0+OsoErOjbVJK0Q+k6ToyDfw9606	rogid:pku0+OsoErOjbVJK0Q+k6ToyDfw9606	rigid:66S8Yfv+VBVMzYSr1z3zfM+iArU	false	sufficient binding region:64-268	sufficient binding region:64-504	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q99972	uniprotkb:P10916	intact:EBI-11692272|uniprotkb:B2RD84|uniprotkb:O00620|uniprotkb:Q7Z6Q9|ensembl:ENSP00000037502	intact:EBI-725770|uniprotkb:Q16123|ensembl:ENSP00000228841	psi-mi:myoc_human(display_long)|uniprotkb:Myocilin 55 kDa subunit(gene name synonym)|uniprotkb:Trabecular meshwork-induced glucocorticoid response protein(gene name synonym)|uniprotkb:MYOC(gene name)|psi-mi:MYOC(display_short)|uniprotkb:GLC1A(gene name synonym)|uniprotkb:TIGR(gene name synonym)	psi-mi:mlrv_human(display_long)|uniprotkb:MYL2(gene name)|psi-mi:MYL2(display_short)|uniprotkb:Cardiac myosin light chain 2(gene name synonym)|uniprotkb:MLC2(gene name synonym)|uniprotkb:Myosin light chain 2, slow skeletal/ventricular muscle isoform(gene name synonym)|uniprotkb:Ventricular myosin light chain 2(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Wentz-Hunter et al. (2002)	pubmed:11773029|imex:IM-25654	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-13635648|imex:IM-25654-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000252.1|ensembl:ENSG00000034971(gene)|ensembl:ENST00000037502(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0001968"(fibronectin binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005929"(cilium)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014734"(skeletal muscle hypertrophy)|go:"GO:0022011"(myelination in peripheral nervous system)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031175"(neuron projection development)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032027"(myosin light chain binding)|go:"GO:0033268"(node of Ranvier)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0038031"(non-canonical Wnt signaling pathway via JNK cascade)|go:"GO:0038133"(ERBB2-ERBB3 signaling pathway)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0045162"(clustering of voltage-gated sodium channels)|go:"GO:0046872"(metal ion binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051901"(positive regulation of mitochondrial depolarization)|go:"GO:0060348"(bone development)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|interpro:IPR003112(Olfactomedin-like)|interpro:IPR031213|rcsb pdb:4WXQ|rcsb pdb:4WXS|rcsb pdb:4WXU|rcsb pdb:6OU0|rcsb pdb:6OU1|rcsb pdb:6OU2|rcsb pdb:6OU3|rcsb pdb:6PKD|rcsb pdb:6PKE|rcsb pdb:6PKF	refseq:NP_000423.2|ensembl:ENSG00000111245(gene)|ensembl:ENST00000228841(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006942"(regulation of striated muscle contraction)|go:"GO:0007507"(heart development)|go:"GO:0016459"(myosin complex)|go:"GO:0030016"(myofibril)|go:"GO:0030017"(sarcomere)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031672"(A band)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060047"(heart contraction)|go:"GO:0097512"(cardiac myofibril)|go:"GO:0098735"(positive regulation of the force of heart contraction)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|rcsb pdb:5TBY|reactome:R-HSA-390522|go:"GO:0008307"(structural constituent of muscle)	-	comment:Full length MYOC as bait did not give interacting clones	-	figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9913(bovin-trabecular meshwork)|taxid:9913(bovin trabecular meshwork)	-	2017/01/23	2017/01/23	rogid:pku0+OsoErOjbVJK0Q+k6ToyDfw9606	rogid:n2YsPUkQrzvaH0/De4h+/K5Q8rE9606	rigid:JAZMQv1eExApUcIbn4q3wW0QJZo	false	sufficient binding region:64-504	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99972	uniprotkb:Q99972	intact:EBI-11692272|uniprotkb:B2RD84|uniprotkb:O00620|uniprotkb:Q7Z6Q9|ensembl:ENSP00000037502	intact:EBI-11692272|uniprotkb:B2RD84|uniprotkb:O00620|uniprotkb:Q7Z6Q9|ensembl:ENSP00000037502	psi-mi:myoc_human(display_long)|uniprotkb:Myocilin 55 kDa subunit(gene name synonym)|uniprotkb:Trabecular meshwork-induced glucocorticoid response protein(gene name synonym)|uniprotkb:MYOC(gene name)|psi-mi:MYOC(display_short)|uniprotkb:GLC1A(gene name synonym)|uniprotkb:TIGR(gene name synonym)	psi-mi:myoc_human(display_long)|uniprotkb:Myocilin 55 kDa subunit(gene name synonym)|uniprotkb:Trabecular meshwork-induced glucocorticoid response protein(gene name synonym)|uniprotkb:MYOC(gene name)|psi-mi:MYOC(display_short)|uniprotkb:GLC1A(gene name synonym)|uniprotkb:TIGR(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Wentz-Hunter et al. (2002)	pubmed:11773029|imex:IM-25654	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-13635655|imex:IM-25654-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000252.1|ensembl:ENSG00000034971(gene)|ensembl:ENST00000037502(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0001968"(fibronectin binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005929"(cilium)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014734"(skeletal muscle hypertrophy)|go:"GO:0022011"(myelination in peripheral nervous system)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031175"(neuron projection development)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032027"(myosin light chain binding)|go:"GO:0033268"(node of Ranvier)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0038031"(non-canonical Wnt signaling pathway via JNK cascade)|go:"GO:0038133"(ERBB2-ERBB3 signaling pathway)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0045162"(clustering of voltage-gated sodium channels)|go:"GO:0046872"(metal ion binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051901"(positive regulation of mitochondrial depolarization)|go:"GO:0060348"(bone development)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|interpro:IPR003112(Olfactomedin-like)|interpro:IPR031213|rcsb pdb:4WXQ|rcsb pdb:4WXS|rcsb pdb:4WXU|rcsb pdb:6OU0|rcsb pdb:6OU1|rcsb pdb:6OU2|rcsb pdb:6OU3|rcsb pdb:6PKD|rcsb pdb:6PKE|rcsb pdb:6PKF	refseq:NP_000252.1|ensembl:ENSG00000034971(gene)|ensembl:ENST00000037502(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0001968"(fibronectin binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005929"(cilium)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014734"(skeletal muscle hypertrophy)|go:"GO:0022011"(myelination in peripheral nervous system)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031175"(neuron projection development)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032027"(myosin light chain binding)|go:"GO:0033268"(node of Ranvier)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0038031"(non-canonical Wnt signaling pathway via JNK cascade)|go:"GO:0038133"(ERBB2-ERBB3 signaling pathway)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0045162"(clustering of voltage-gated sodium channels)|go:"GO:0046872"(metal ion binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051901"(positive regulation of mitochondrial depolarization)|go:"GO:0060348"(bone development)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|interpro:IPR003112(Olfactomedin-like)|interpro:IPR031213|rcsb pdb:4WXQ|rcsb pdb:4WXS|rcsb pdb:4WXU|rcsb pdb:6OU0|rcsb pdb:6OU1|rcsb pdb:6OU2|rcsb pdb:6OU3|rcsb pdb:6PKD|rcsb pdb:6PKE|rcsb pdb:6PKF	-	-	comment:Full length MYOC as bait did not give interacting clones	figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9913(bovin-trabecular meshwork)|taxid:9913(bovin trabecular meshwork)	-	2017/01/23	2017/01/23	rogid:pku0+OsoErOjbVJK0Q+k6ToyDfw9606	rogid:pku0+OsoErOjbVJK0Q+k6ToyDfw9606	rigid:66S8Yfv+VBVMzYSr1z3zfM+iArU	false	sufficient binding region:64-504	sufficient binding region:64-504	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P10916	uniprotkb:Q99972	intact:EBI-725770|uniprotkb:Q16123|ensembl:ENSP00000228841	intact:EBI-11692272|uniprotkb:B2RD84|uniprotkb:O00620|uniprotkb:Q7Z6Q9|ensembl:ENSP00000037502	psi-mi:mlrv_human(display_long)|uniprotkb:MYL2(gene name)|psi-mi:MYL2(display_short)|uniprotkb:Cardiac myosin light chain 2(gene name synonym)|uniprotkb:MLC2(gene name synonym)|uniprotkb:Myosin light chain 2, slow skeletal/ventricular muscle isoform(gene name synonym)|uniprotkb:Ventricular myosin light chain 2(gene name synonym)	psi-mi:myoc_human(display_long)|uniprotkb:Myocilin 55 kDa subunit(gene name synonym)|uniprotkb:Trabecular meshwork-induced glucocorticoid response protein(gene name synonym)|uniprotkb:MYOC(gene name)|psi-mi:MYOC(display_short)|uniprotkb:GLC1A(gene name synonym)|uniprotkb:TIGR(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wentz-Hunter et al. (2002)	pubmed:11773029|imex:IM-25654	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-13635690|imex:IM-25654-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000423.2|ensembl:ENSG00000111245(gene)|ensembl:ENST00000228841(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006942"(regulation of striated muscle contraction)|go:"GO:0007507"(heart development)|go:"GO:0016459"(myosin complex)|go:"GO:0030016"(myofibril)|go:"GO:0030017"(sarcomere)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031672"(A band)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060047"(heart contraction)|go:"GO:0097512"(cardiac myofibril)|go:"GO:0098735"(positive regulation of the force of heart contraction)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|rcsb pdb:5TBY|reactome:R-HSA-390522|go:"GO:0008307"(structural constituent of muscle)	refseq:NP_000252.1|ensembl:ENSG00000034971(gene)|ensembl:ENST00000037502(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0001968"(fibronectin binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005929"(cilium)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014734"(skeletal muscle hypertrophy)|go:"GO:0022011"(myelination in peripheral nervous system)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031175"(neuron projection development)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032027"(myosin light chain binding)|go:"GO:0033268"(node of Ranvier)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0038031"(non-canonical Wnt signaling pathway via JNK cascade)|go:"GO:0038133"(ERBB2-ERBB3 signaling pathway)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0045162"(clustering of voltage-gated sodium channels)|go:"GO:0046872"(metal ion binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051901"(positive regulation of mitochondrial depolarization)|go:"GO:0060348"(bone development)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|interpro:IPR003112(Olfactomedin-like)|interpro:IPR031213|rcsb pdb:4WXQ|rcsb pdb:4WXS|rcsb pdb:4WXU|rcsb pdb:6OU0|rcsb pdb:6OU1|rcsb pdb:6OU2|rcsb pdb:6OU3|rcsb pdb:6PKD|rcsb pdb:6PKE|rcsb pdb:6PKF	-	-	-	figure legend:1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/01/23	2017/01/23	rogid:n2YsPUkQrzvaH0/De4h+/K5Q8rE9606	rogid:pku0+OsoErOjbVJK0Q+k6ToyDfw9606	rigid:JAZMQv1eExApUcIbn4q3wW0QJZo	false	35s radiolabel:?-?|ha tag:?-?	myc tag:?-?|35s radiolabel:?-?|sufficient binding region:64-504	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:P10916	uniprotkb:Q99972	intact:EBI-725770|uniprotkb:Q16123|ensembl:ENSP00000228841	intact:EBI-11692272|uniprotkb:B2RD84|uniprotkb:O00620|uniprotkb:Q7Z6Q9|ensembl:ENSP00000037502	psi-mi:mlrv_human(display_long)|uniprotkb:MYL2(gene name)|psi-mi:MYL2(display_short)|uniprotkb:Cardiac myosin light chain 2(gene name synonym)|uniprotkb:MLC2(gene name synonym)|uniprotkb:Myosin light chain 2, slow skeletal/ventricular muscle isoform(gene name synonym)|uniprotkb:Ventricular myosin light chain 2(gene name synonym)	psi-mi:myoc_human(display_long)|uniprotkb:Myocilin 55 kDa subunit(gene name synonym)|uniprotkb:Trabecular meshwork-induced glucocorticoid response protein(gene name synonym)|uniprotkb:MYOC(gene name)|psi-mi:MYOC(display_short)|uniprotkb:GLC1A(gene name synonym)|uniprotkb:TIGR(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wentz-Hunter et al. (2002)	pubmed:11773029|imex:IM-25654	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-13635706|imex:IM-25654-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000423.2|ensembl:ENSG00000111245(gene)|ensembl:ENST00000228841(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006942"(regulation of striated muscle contraction)|go:"GO:0007507"(heart development)|go:"GO:0016459"(myosin complex)|go:"GO:0030016"(myofibril)|go:"GO:0030017"(sarcomere)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031672"(A band)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060047"(heart contraction)|go:"GO:0097512"(cardiac myofibril)|go:"GO:0098735"(positive regulation of the force of heart contraction)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|rcsb pdb:5TBY|reactome:R-HSA-390522|go:"GO:0008307"(structural constituent of muscle)	refseq:NP_000252.1|ensembl:ENSG00000034971(gene)|ensembl:ENST00000037502(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0001968"(fibronectin binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005929"(cilium)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014734"(skeletal muscle hypertrophy)|go:"GO:0022011"(myelination in peripheral nervous system)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031175"(neuron projection development)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032027"(myosin light chain binding)|go:"GO:0033268"(node of Ranvier)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0038031"(non-canonical Wnt signaling pathway via JNK cascade)|go:"GO:0038133"(ERBB2-ERBB3 signaling pathway)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0045162"(clustering of voltage-gated sodium channels)|go:"GO:0046872"(metal ion binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051901"(positive regulation of mitochondrial depolarization)|go:"GO:0060348"(bone development)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|interpro:IPR003112(Olfactomedin-like)|interpro:IPR031213|rcsb pdb:4WXQ|rcsb pdb:4WXS|rcsb pdb:4WXU|rcsb pdb:6OU0|rcsb pdb:6OU1|rcsb pdb:6OU2|rcsb pdb:6OU3|rcsb pdb:6PKD|rcsb pdb:6PKE|rcsb pdb:6PKF	-	-	-	figure legend:1 and 5B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/01/23	2017/01/23	rogid:n2YsPUkQrzvaH0/De4h+/K5Q8rE9606	rogid:pku0+OsoErOjbVJK0Q+k6ToyDfw9606	rigid:JAZMQv1eExApUcIbn4q3wW0QJZo	false	35s radiolabel:?-?|ha tag:?-?	myc tag:?-?|35s radiolabel:?-?|sufficient binding region:64-226	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:Q99972	uniprotkb:P10916	intact:EBI-11692272|uniprotkb:B2RD84|uniprotkb:O00620|uniprotkb:Q7Z6Q9|ensembl:ENSP00000037502	intact:EBI-725770|uniprotkb:Q16123|ensembl:ENSP00000228841	psi-mi:myoc_human(display_long)|uniprotkb:Myocilin 55 kDa subunit(gene name synonym)|uniprotkb:Trabecular meshwork-induced glucocorticoid response protein(gene name synonym)|uniprotkb:MYOC(gene name)|psi-mi:MYOC(display_short)|uniprotkb:GLC1A(gene name synonym)|uniprotkb:TIGR(gene name synonym)	psi-mi:mlrv_human(display_long)|uniprotkb:MYL2(gene name)|psi-mi:MYL2(display_short)|uniprotkb:Cardiac myosin light chain 2(gene name synonym)|uniprotkb:MLC2(gene name synonym)|uniprotkb:Myosin light chain 2, slow skeletal/ventricular muscle isoform(gene name synonym)|uniprotkb:Ventricular myosin light chain 2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wentz-Hunter et al. (2002)	pubmed:11773029|imex:IM-25654	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-13635730|imex:IM-25654-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000252.1|ensembl:ENSG00000034971(gene)|ensembl:ENST00000037502(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0001968"(fibronectin binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005929"(cilium)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014734"(skeletal muscle hypertrophy)|go:"GO:0022011"(myelination in peripheral nervous system)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031175"(neuron projection development)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032027"(myosin light chain binding)|go:"GO:0033268"(node of Ranvier)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0038031"(non-canonical Wnt signaling pathway via JNK cascade)|go:"GO:0038133"(ERBB2-ERBB3 signaling pathway)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0045162"(clustering of voltage-gated sodium channels)|go:"GO:0046872"(metal ion binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051901"(positive regulation of mitochondrial depolarization)|go:"GO:0060348"(bone development)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|interpro:IPR003112(Olfactomedin-like)|interpro:IPR031213|rcsb pdb:4WXQ|rcsb pdb:4WXS|rcsb pdb:4WXU|rcsb pdb:6OU0|rcsb pdb:6OU1|rcsb pdb:6OU2|rcsb pdb:6OU3|rcsb pdb:6PKD|rcsb pdb:6PKE|rcsb pdb:6PKF	refseq:NP_000423.2|ensembl:ENSG00000111245(gene)|ensembl:ENST00000228841(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006942"(regulation of striated muscle contraction)|go:"GO:0007507"(heart development)|go:"GO:0016459"(myosin complex)|go:"GO:0030016"(myofibril)|go:"GO:0030017"(sarcomere)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031672"(A band)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060047"(heart contraction)|go:"GO:0097512"(cardiac myofibril)|go:"GO:0098735"(positive regulation of the force of heart contraction)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|rcsb pdb:5TBY|reactome:R-HSA-390522|go:"GO:0008307"(structural constituent of muscle)	-	-	-	figure legend:2A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-trabecular meshwork)|taxid:9606(Homo sapiens trabecular meshwork)	-	2017/01/23	2017/01/23	rogid:pku0+OsoErOjbVJK0Q+k6ToyDfw9606	rogid:n2YsPUkQrzvaH0/De4h+/K5Q8rE9606	rigid:JAZMQv1eExApUcIbn4q3wW0QJZo	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q99972	uniprotkb:P10916	intact:EBI-11692272|uniprotkb:B2RD84|uniprotkb:O00620|uniprotkb:Q7Z6Q9|ensembl:ENSP00000037502	intact:EBI-725770|uniprotkb:Q16123|ensembl:ENSP00000228841	psi-mi:myoc_human(display_long)|uniprotkb:Myocilin 55 kDa subunit(gene name synonym)|uniprotkb:Trabecular meshwork-induced glucocorticoid response protein(gene name synonym)|uniprotkb:MYOC(gene name)|psi-mi:MYOC(display_short)|uniprotkb:GLC1A(gene name synonym)|uniprotkb:TIGR(gene name synonym)	psi-mi:mlrv_human(display_long)|uniprotkb:MYL2(gene name)|psi-mi:MYL2(display_short)|uniprotkb:Cardiac myosin light chain 2(gene name synonym)|uniprotkb:MLC2(gene name synonym)|uniprotkb:Myosin light chain 2, slow skeletal/ventricular muscle isoform(gene name synonym)|uniprotkb:Ventricular myosin light chain 2(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Wentz-Hunter et al. (2002)	pubmed:11773029|imex:IM-25654	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0486"(UniProt)	intact:EBI-13635740|imex:IM-25654-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000252.1|ensembl:ENSG00000034971(gene)|ensembl:ENST00000037502(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0001968"(fibronectin binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005929"(cilium)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014734"(skeletal muscle hypertrophy)|go:"GO:0022011"(myelination in peripheral nervous system)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031175"(neuron projection development)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032027"(myosin light chain binding)|go:"GO:0033268"(node of Ranvier)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0038031"(non-canonical Wnt signaling pathway via JNK cascade)|go:"GO:0038133"(ERBB2-ERBB3 signaling pathway)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0045162"(clustering of voltage-gated sodium channels)|go:"GO:0046872"(metal ion binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051901"(positive regulation of mitochondrial depolarization)|go:"GO:0060348"(bone development)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|interpro:IPR003112(Olfactomedin-like)|interpro:IPR031213|rcsb pdb:4WXQ|rcsb pdb:4WXS|rcsb pdb:4WXU|rcsb pdb:6OU0|rcsb pdb:6OU1|rcsb pdb:6OU2|rcsb pdb:6OU3|rcsb pdb:6PKD|rcsb pdb:6PKE|rcsb pdb:6PKF	refseq:NP_000423.2|ensembl:ENSG00000111245(gene)|ensembl:ENST00000228841(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006942"(regulation of striated muscle contraction)|go:"GO:0007507"(heart development)|go:"GO:0016459"(myosin complex)|go:"GO:0030016"(myofibril)|go:"GO:0030017"(sarcomere)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031672"(A band)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060047"(heart contraction)|go:"GO:0097512"(cardiac myofibril)|go:"GO:0098735"(positive regulation of the force of heart contraction)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|rcsb pdb:5TBY|reactome:R-HSA-390522|go:"GO:0008307"(structural constituent of muscle)	go:"GO:0048471"(perinuclear region of cytoplasm)	-	-	figure legend:3|comment:colocalization on fibrillar structures|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-trabecular meshwork)|taxid:9606(Homo sapiens trabecular meshwork)	-	2017/01/23	2017/01/23	rogid:pku0+OsoErOjbVJK0Q+k6ToyDfw9606	rogid:n2YsPUkQrzvaH0/De4h+/K5Q8rE9606	rigid:JAZMQv1eExApUcIbn4q3wW0QJZo	false	-	-	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:Q99972	uniprotkb:P10916	intact:EBI-11692272|uniprotkb:B2RD84|uniprotkb:O00620|uniprotkb:Q7Z6Q9|ensembl:ENSP00000037502	intact:EBI-725770|uniprotkb:Q16123|ensembl:ENSP00000228841	psi-mi:myoc_human(display_long)|uniprotkb:Myocilin 55 kDa subunit(gene name synonym)|uniprotkb:Trabecular meshwork-induced glucocorticoid response protein(gene name synonym)|uniprotkb:MYOC(gene name)|psi-mi:MYOC(display_short)|uniprotkb:GLC1A(gene name synonym)|uniprotkb:TIGR(gene name synonym)	psi-mi:mlrv_human(display_long)|uniprotkb:MYL2(gene name)|psi-mi:MYL2(display_short)|uniprotkb:Cardiac myosin light chain 2(gene name synonym)|uniprotkb:MLC2(gene name synonym)|uniprotkb:Myosin light chain 2, slow skeletal/ventricular muscle isoform(gene name synonym)|uniprotkb:Ventricular myosin light chain 2(gene name synonym)	psi-mi:"MI:0040"(electron microscopy)	Wentz-Hunter et al. (2002)	pubmed:11773029|imex:IM-25654	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0486"(UniProt)	intact:EBI-13635753|imex:IM-25654-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000252.1|ensembl:ENSG00000034971(gene)|ensembl:ENST00000037502(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0001968"(fibronectin binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005929"(cilium)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014734"(skeletal muscle hypertrophy)|go:"GO:0022011"(myelination in peripheral nervous system)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031175"(neuron projection development)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032027"(myosin light chain binding)|go:"GO:0033268"(node of Ranvier)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0038031"(non-canonical Wnt signaling pathway via JNK cascade)|go:"GO:0038133"(ERBB2-ERBB3 signaling pathway)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0045162"(clustering of voltage-gated sodium channels)|go:"GO:0046872"(metal ion binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051901"(positive regulation of mitochondrial depolarization)|go:"GO:0060348"(bone development)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|interpro:IPR003112(Olfactomedin-like)|interpro:IPR031213|rcsb pdb:4WXQ|rcsb pdb:4WXS|rcsb pdb:4WXU|rcsb pdb:6OU0|rcsb pdb:6OU1|rcsb pdb:6OU2|rcsb pdb:6OU3|rcsb pdb:6PKD|rcsb pdb:6PKE|rcsb pdb:6PKF	refseq:NP_000423.2|ensembl:ENSG00000111245(gene)|ensembl:ENST00000228841(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006942"(regulation of striated muscle contraction)|go:"GO:0007507"(heart development)|go:"GO:0016459"(myosin complex)|go:"GO:0030016"(myofibril)|go:"GO:0030017"(sarcomere)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031672"(A band)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060047"(heart contraction)|go:"GO:0097512"(cardiac myofibril)|go:"GO:0098735"(positive regulation of the force of heart contraction)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|rcsb pdb:5TBY|reactome:R-HSA-390522|go:"GO:0008307"(structural constituent of muscle)	go:"GO:0001725"(stress fiber)	-	-	figure legend:4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-trabecular meshwork)|taxid:9606(Homo sapiens trabecular meshwork)	-	2017/01/23	2017/01/23	rogid:pku0+OsoErOjbVJK0Q+k6ToyDfw9606	rogid:n2YsPUkQrzvaH0/De4h+/K5Q8rE9606	rigid:JAZMQv1eExApUcIbn4q3wW0QJZo	false	-	-	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)