#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B intact:EBI-16420196 uniprotkb:P11325 - intact:EBI-18753|uniprotkb:D6VZ17|ensemblfungi:YLR382C psi-mi:bi4_intron_yeast_mrna(display_short)|psi-mi:EBI-16420196(display_long) psi-mi:sylm_yeast(display_long)|uniprotkb:NAM2(gene name)|psi-mi:NAM2(display_short)|uniprotkb:MSL1(gene name synonym)|uniprotkb:YLR382C(locus name)|uniprotkb:L3502.6(orf name)|uniprotkb:Leucyl-tRNA synthetase(gene name synonym) psi-mi:"MI:0438"(rna three hybrid) Rho et al. (2000) pubmed:11142386|imex:IM-26203 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-16420203|imex:IM-26203-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0324"(messenger rna) psi-mi:"MI:0326"(protein) - sgd:S000004374|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR002300(Aminoacyl-tRNA synthetase, class Ia)|interpro:IPR002302(Leucyl-tRNA synthetase, class Ia, bacterial/mitochondrial)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR009008(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class Ia, editing)|interpro:IPR025709|interpro:IPR015413("Aminoacyl-tRNA synthetase, class I (M)")|ensemblfungi:YLR382C(gene)|ensemblfungi:YLR382C_mRNA(transcript)|go:"GO:0000372"(Group I intron splicing)|go:"GO:0002161"(aminoacyl-tRNA editing activity)|go:"GO:0004823"(leucine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006429"(leucyl-tRNA aminoacylation)|go:"GO:0032543"(mitochondrial translation)|go:"GO:0097157"(pre-mRNA intronic binding)|refseq:NP_013486.3|mint:P11325 - - - figure legend:Fig. 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/09/26 2017/09/26 - rogid:EQVBYS0O87N1Je6L+4nFlaM8vQc559292 - false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) intact:EBI-16420196 uniprotkb:P03879 - intact:EBI-16420207|ensemblfungi:Q0120|uniprotkb:A0A0A7NYH9|uniprotkb:Q02324|uniprotkb:Q9ZZW6 psi-mi:bi4_intron_yeast_mrna(display_short)|psi-mi:EBI-16420196(display_long) psi-mi:mbi4_yeast(display_long)|uniprotkb:RNA maturase SCbI4(gene name synonym)|uniprotkb:BI4(gene name)|psi-mi:BI4(display_short)|uniprotkb:SCBI4(gene name synonym)|uniprotkb:Q0120(locus name) psi-mi:"MI:0438"(rna three hybrid) Rho et al. (2000) pubmed:11142386|imex:IM-26203 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-16420227|imex:IM-26203-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0324"(messenger rna) psi-mi:"MI:0326"(protein) - reactome:R-SCE-611105|ensemblfungi:Q0120(gene)|ensemblfungi:Q0120_mRNA(transcript)|go:"GO:0000372"(Group I intron splicing)|go:"GO:0003723"(RNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0090615"(mitochondrial mRNA processing)|refseq:NP_009316.1|interpro:IPR005797(Cytochrome b/b6, N-terminal)|interpro:IPR027387|interpro:IPR016174(Transmembrane di-haem cytochrome)|interpro:IPR027434|interpro:IPR004860(LAGLIDADG DNA endonuclease)|sgd:S000007273 - - - figure legend:Fig. 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/09/26 2017/09/26 - rogid:lr6bRF/m7gXrA9iTA4kQG7R7TLM559292 - false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P03879 intact:EBI-16420196 intact:EBI-16420207|ensemblfungi:Q0120|uniprotkb:A0A0A7NYH9|uniprotkb:Q02324|uniprotkb:Q9ZZW6 - psi-mi:mbi4_yeast(display_long)|uniprotkb:RNA maturase SCbI4(gene name synonym)|uniprotkb:BI4(gene name)|psi-mi:BI4(display_short)|uniprotkb:SCBI4(gene name synonym)|uniprotkb:Q0120(locus name) psi-mi:bi4_intron_yeast_mrna(display_short)|psi-mi:EBI-16420196(display_long) psi-mi:"MI:0018"(two hybrid) Rho et al. (2000) pubmed:11142386|imex:IM-26203 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-16420236|imex:IM-26203-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0684"(ancillary) psi-mi:"MI:0326"(protein) psi-mi:"MI:0324"(messenger rna) reactome:R-SCE-611105|ensemblfungi:Q0120(gene)|ensemblfungi:Q0120_mRNA(transcript)|go:"GO:0000372"(Group I intron splicing)|go:"GO:0003723"(RNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0090615"(mitochondrial mRNA processing)|refseq:NP_009316.1|interpro:IPR005797(Cytochrome b/b6, N-terminal)|interpro:IPR027387|interpro:IPR016174(Transmembrane di-haem cytochrome)|interpro:IPR027434|interpro:IPR004860(LAGLIDADG DNA endonuclease)|sgd:S000007273 - - - - figure legend:Fig. 5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/09/26 2017/09/26 rogid:lr6bRF/m7gXrA9iTA4kQG7R7TLM559292 - - false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P03879 uniprotkb:P11325 intact:EBI-16420207|ensemblfungi:Q0120|uniprotkb:A0A0A7NYH9|uniprotkb:Q02324|uniprotkb:Q9ZZW6 intact:EBI-18753|uniprotkb:D6VZ17|ensemblfungi:YLR382C psi-mi:mbi4_yeast(display_long)|uniprotkb:RNA maturase SCbI4(gene name synonym)|uniprotkb:BI4(gene name)|psi-mi:BI4(display_short)|uniprotkb:SCBI4(gene name synonym)|uniprotkb:Q0120(locus name) psi-mi:sylm_yeast(display_long)|uniprotkb:NAM2(gene name)|psi-mi:NAM2(display_short)|uniprotkb:MSL1(gene name synonym)|uniprotkb:YLR382C(locus name)|uniprotkb:L3502.6(orf name)|uniprotkb:Leucyl-tRNA synthetase(gene name synonym) psi-mi:"MI:0018"(two hybrid) Rho et al. (2000) pubmed:11142386|imex:IM-26203 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-16420236|imex:IM-26203-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-SCE-611105|ensemblfungi:Q0120(gene)|ensemblfungi:Q0120_mRNA(transcript)|go:"GO:0000372"(Group I intron splicing)|go:"GO:0003723"(RNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0090615"(mitochondrial mRNA processing)|refseq:NP_009316.1|interpro:IPR005797(Cytochrome b/b6, N-terminal)|interpro:IPR027387|interpro:IPR016174(Transmembrane di-haem cytochrome)|interpro:IPR027434|interpro:IPR004860(LAGLIDADG DNA endonuclease)|sgd:S000007273 sgd:S000004374|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR002300(Aminoacyl-tRNA synthetase, class Ia)|interpro:IPR002302(Leucyl-tRNA synthetase, class Ia, bacterial/mitochondrial)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR009008(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class Ia, editing)|interpro:IPR025709|interpro:IPR015413("Aminoacyl-tRNA synthetase, class I (M)")|ensemblfungi:YLR382C(gene)|ensemblfungi:YLR382C_mRNA(transcript)|go:"GO:0000372"(Group I intron splicing)|go:"GO:0002161"(aminoacyl-tRNA editing activity)|go:"GO:0004823"(leucine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006429"(leucyl-tRNA aminoacylation)|go:"GO:0032543"(mitochondrial translation)|go:"GO:0097157"(pre-mRNA intronic binding)|refseq:NP_013486.3|mint:P11325 - - - figure legend:Fig. 5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/09/26 2017/09/26 rogid:lr6bRF/m7gXrA9iTA4kQG7R7TLM559292 rogid:EQVBYS0O87N1Je6L+4nFlaM8vQc559292 - false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P11325 intact:EBI-16420196 intact:EBI-18753|uniprotkb:D6VZ17|ensemblfungi:YLR382C - psi-mi:sylm_yeast(display_long)|uniprotkb:NAM2(gene name)|psi-mi:NAM2(display_short)|uniprotkb:MSL1(gene name synonym)|uniprotkb:YLR382C(locus name)|uniprotkb:L3502.6(orf name)|uniprotkb:Leucyl-tRNA synthetase(gene name synonym) psi-mi:bi4_intron_yeast_mrna(display_short)|psi-mi:EBI-16420196(display_long) psi-mi:"MI:0018"(two hybrid) Rho et al. (2000) pubmed:11142386|imex:IM-26203 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-16420240|imex:IM-26203-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0684"(ancillary) psi-mi:"MI:0326"(protein) psi-mi:"MI:0324"(messenger rna) sgd:S000004374|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR002300(Aminoacyl-tRNA synthetase, class Ia)|interpro:IPR002302(Leucyl-tRNA synthetase, class Ia, bacterial/mitochondrial)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR009008(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class Ia, editing)|interpro:IPR025709|interpro:IPR015413("Aminoacyl-tRNA synthetase, class I (M)")|ensemblfungi:YLR382C(gene)|ensemblfungi:YLR382C_mRNA(transcript)|go:"GO:0000372"(Group I intron splicing)|go:"GO:0002161"(aminoacyl-tRNA editing activity)|go:"GO:0004823"(leucine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006429"(leucyl-tRNA aminoacylation)|go:"GO:0032543"(mitochondrial translation)|go:"GO:0097157"(pre-mRNA intronic binding)|refseq:NP_013486.3|mint:P11325 - - - - figure legend:Fig. 5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/09/26 2017/09/26 rogid:EQVBYS0O87N1Je6L+4nFlaM8vQc559292 - - false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P11325 uniprotkb:P03879 intact:EBI-18753|uniprotkb:D6VZ17|ensemblfungi:YLR382C intact:EBI-16420207|ensemblfungi:Q0120|uniprotkb:A0A0A7NYH9|uniprotkb:Q02324|uniprotkb:Q9ZZW6 psi-mi:sylm_yeast(display_long)|uniprotkb:NAM2(gene name)|psi-mi:NAM2(display_short)|uniprotkb:MSL1(gene name synonym)|uniprotkb:YLR382C(locus name)|uniprotkb:L3502.6(orf name)|uniprotkb:Leucyl-tRNA synthetase(gene name synonym) psi-mi:mbi4_yeast(display_long)|uniprotkb:RNA maturase SCbI4(gene name synonym)|uniprotkb:BI4(gene name)|psi-mi:BI4(display_short)|uniprotkb:SCBI4(gene name synonym)|uniprotkb:Q0120(locus name) psi-mi:"MI:0018"(two hybrid) Rho et al. (2000) pubmed:11142386|imex:IM-26203 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-16420240|imex:IM-26203-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000004374|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR002300(Aminoacyl-tRNA synthetase, class Ia)|interpro:IPR002302(Leucyl-tRNA synthetase, class Ia, bacterial/mitochondrial)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR009008(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class Ia, editing)|interpro:IPR025709|interpro:IPR015413("Aminoacyl-tRNA synthetase, class I (M)")|ensemblfungi:YLR382C(gene)|ensemblfungi:YLR382C_mRNA(transcript)|go:"GO:0000372"(Group I intron splicing)|go:"GO:0002161"(aminoacyl-tRNA editing activity)|go:"GO:0004823"(leucine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006429"(leucyl-tRNA aminoacylation)|go:"GO:0032543"(mitochondrial translation)|go:"GO:0097157"(pre-mRNA intronic binding)|refseq:NP_013486.3|mint:P11325 reactome:R-SCE-611105|ensemblfungi:Q0120(gene)|ensemblfungi:Q0120_mRNA(transcript)|go:"GO:0000372"(Group I intron splicing)|go:"GO:0003723"(RNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0090615"(mitochondrial mRNA processing)|refseq:NP_009316.1|interpro:IPR005797(Cytochrome b/b6, N-terminal)|interpro:IPR027387|interpro:IPR016174(Transmembrane di-haem cytochrome)|interpro:IPR027434|interpro:IPR004860(LAGLIDADG DNA endonuclease)|sgd:S000007273 - - - figure legend:Fig. 5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/09/26 2017/09/26 rogid:EQVBYS0O87N1Je6L+4nFlaM8vQc559292 rogid:lr6bRF/m7gXrA9iTA4kQG7R7TLM559292 - false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P41252 uniprotkb:P07814 intact:EBI-355303|uniprotkb:Q5TCD0|uniprotkb:Q9H588|uniprotkb:A8KAE9|uniprotkb:Q7Z3T4|ensembl:ENSP00000364794|ensembl:ENSP00000406448|ensembl:ENSP00000507144 intact:EBI-355315|uniprotkb:Q5H9S5|uniprotkb:Q6PD57|uniprotkb:Q86X73|uniprotkb:A0AVA9|uniprotkb:Q05BP6|uniprotkb:Q05DF8|uniprotkb:Q5DSM1|ensembl:ENSP00000355890|uniprotkb:B9EGH3 psi-mi:syic_human(display_long)|uniprotkb:IARS1(gene name)|psi-mi:IARS1(display_short)|uniprotkb:IARS(gene name synonym)|uniprotkb:Isoleucyl-tRNA synthetase(gene name synonym) psi-mi:syep_human(display_long)|uniprotkb:EPRS1(gene name)|psi-mi:EPRS1(display_short)|uniprotkb:Bifunctional aminoacyl-tRNA synthetase(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 32 protein(gene name synonym)|uniprotkb:EPRS(gene name synonym)|uniprotkb:GLNS(gene name synonym)|uniprotkb:Glutamatyl-prolyl-tRNA synthetase(gene name synonym)|uniprotkb:PARS(gene name synonym)|uniprotkb:QARS(gene name synonym)|uniprotkb:QPRS(gene name synonym)|uniprotkb:PIG32(orf name) psi-mi:"MI:0018"(two hybrid) Rho et al. (2000) pubmed:11142386|imex:IM-26203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-16420247|imex:IM-26203-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002152.2|refseq:NP_038203.2|ensembl:ENSG00000196305(gene)|ensembl:ENST00000375643(transcript)|ensembl:ENST00000443024(transcript)|ensembl:ENST00000683565(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0002161"(aminoacyl-tRNA editing activity)|go:"GO:0004822"(isoleucine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006418"(tRNA aminoacylation for protein translation)|go:"GO:0006428"(isoleucyl-tRNA aminoacylation)|go:"GO:0016020"(membrane)|go:"GO:0017101"(aminoacyl-tRNA synthetase multienzyme complex)|go:"GO:0051020"(GTPase binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR002300(Aminoacyl-tRNA synthetase, class Ia)|interpro:IPR002301(Isoleucyl-tRNA synthetase, class Ia)|interpro:IPR009008(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class Ia, editing)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR013155(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR023586|interpro:IPR033709|mint:P41252|reactome:R-HSA-2408522|reactome:R-HSA-379716 refseq:NP_004437.2|ensembl:ENSG00000136628(gene)|ensembl:ENST00000366923(transcript)|go:"GO:0004818"(glutamate-tRNA ligase activity)|go:"GO:0004827"(proline-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006418"(tRNA aminoacylation for protein translation)|go:"GO:0006424"(glutamyl-tRNA aminoacylation)|go:"GO:0006433"(prolyl-tRNA aminoacylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0017101"(aminoacyl-tRNA synthetase multienzyme complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0051020"(GTPase binding)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097452"(GAIT complex)|go:"GO:0140212"(regulation of long-chain fatty acid import into cell)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000738(WHEP-TRS)|interpro:IPR000924(Glutamyl/glutaminyl-tRNA synthetase, class Ic)|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR002314("Aminoacyl-tRNA synthetase, class II (G, H, P and S)")|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR004154(Anticodon-binding)|interpro:IPR004499(Prolyl-tRNA synthetase, class IIa, prokaryotic-type)|interpro:IPR004526(Glutamyl-tRNA synthetase, class Ic, archaeal/eukaryotic cytosolic)|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR011035(Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR016061(Prolyl-tRNA synthetase, class II, C-terminal)|interpro:IPR017449(Prolyl-tRNA synthetase, class II)|interpro:IPR020056|interpro:IPR020058|interpro:IPR020059|interpro:IPR033721|interpro:IPR036282|interpro:IPR036621|mint:P07814|rcsb pdb:1FYJ|rcsb pdb:4HVC|rcsb pdb:4K86|rcsb pdb:4K87|rcsb pdb:4K88|rcsb pdb:5A1N|rcsb pdb:5A34|rcsb pdb:5A5H|rcsb pdb:5BMU|rcsb pdb:5V58|rcsb pdb:5VAD|rcsb pdb:5Y6L|rcsb pdb:6IY6|reactome:R-HSA-2408522|reactome:R-HSA-379716|reactome:R-HSA-6782315|dip:DIP-40825N - - - figure legend:Fig. 5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/09/26 2017/09/26 rogid:maAJX/O1Ryxr5NVFQEWvXNgHXyY9606 rogid:67nL6JkhNTSttOucQt3mLRQZeLY9606 rigid:UsKBkEpc20pntbZ3Qf2TrL+UhVs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) intact:EBI-16420196 uniprotkb:P11325 - intact:EBI-18753|uniprotkb:D6VZ17|ensemblfungi:YLR382C psi-mi:bi4_intron_yeast_mrna(display_short)|psi-mi:EBI-16420196(display_long) psi-mi:sylm_yeast(display_long)|uniprotkb:NAM2(gene name)|psi-mi:NAM2(display_short)|uniprotkb:MSL1(gene name synonym)|uniprotkb:YLR382C(locus name)|uniprotkb:L3502.6(orf name)|uniprotkb:Leucyl-tRNA synthetase(gene name synonym) psi-mi:"MI:0588"(three hybrid) Rho et al. (2000) pubmed:11142386|imex:IM-26203 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-16425323|imex:IM-26203-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0324"(messenger rna) psi-mi:"MI:0326"(protein) - sgd:S000004374|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR002300(Aminoacyl-tRNA synthetase, class Ia)|interpro:IPR002302(Leucyl-tRNA synthetase, class Ia, bacterial/mitochondrial)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR009008(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class Ia, editing)|interpro:IPR025709|interpro:IPR015413("Aminoacyl-tRNA synthetase, class I (M)")|ensemblfungi:YLR382C(gene)|ensemblfungi:YLR382C_mRNA(transcript)|go:"GO:0000372"(Group I intron splicing)|go:"GO:0002161"(aminoacyl-tRNA editing activity)|go:"GO:0004823"(leucine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006429"(leucyl-tRNA aminoacylation)|go:"GO:0032543"(mitochondrial translation)|go:"GO:0097157"(pre-mRNA intronic binding)|refseq:NP_013486.3|mint:P11325 - - - figure legend:Fig. 7|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/09/26 2017/10/09 - rogid:EQVBYS0O87N1Je6L+4nFlaM8vQc559292 - false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) intact:EBI-16420196 uniprotkb:P03879 - intact:EBI-16420207|ensemblfungi:Q0120|uniprotkb:A0A0A7NYH9|uniprotkb:Q02324|uniprotkb:Q9ZZW6 psi-mi:bi4_intron_yeast_mrna(display_short)|psi-mi:EBI-16420196(display_long) psi-mi:mbi4_yeast(display_long)|uniprotkb:RNA maturase SCbI4(gene name synonym)|uniprotkb:BI4(gene name)|psi-mi:BI4(display_short)|uniprotkb:SCBI4(gene name synonym)|uniprotkb:Q0120(locus name) psi-mi:"MI:0588"(three hybrid) Rho et al. (2000) pubmed:11142386|imex:IM-26203 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-16425323|imex:IM-26203-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0496"(bait) psi-mi:"MI:0324"(messenger rna) psi-mi:"MI:0326"(protein) - reactome:R-SCE-611105|ensemblfungi:Q0120(gene)|ensemblfungi:Q0120_mRNA(transcript)|go:"GO:0000372"(Group I intron splicing)|go:"GO:0003723"(RNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0090615"(mitochondrial mRNA processing)|refseq:NP_009316.1|interpro:IPR005797(Cytochrome b/b6, N-terminal)|interpro:IPR027387|interpro:IPR016174(Transmembrane di-haem cytochrome)|interpro:IPR027434|interpro:IPR004860(LAGLIDADG DNA endonuclease)|sgd:S000007273 - - - figure legend:Fig. 7|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/09/26 2017/10/09 - rogid:lr6bRF/m7gXrA9iTA4kQG7R7TLM559292 - false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P11325 intact:EBI-16420196 intact:EBI-18753|uniprotkb:D6VZ17|ensemblfungi:YLR382C - psi-mi:sylm_yeast(display_long)|uniprotkb:NAM2(gene name)|psi-mi:NAM2(display_short)|uniprotkb:MSL1(gene name synonym)|uniprotkb:YLR382C(locus name)|uniprotkb:L3502.6(orf name)|uniprotkb:Leucyl-tRNA synthetase(gene name synonym) psi-mi:bi4_intron_yeast_mrna(display_short)|psi-mi:EBI-16420196(display_long) psi-mi:"MI:0588"(three hybrid) Rho et al. (2000) pubmed:11142386|imex:IM-26203 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-16425328|imex:IM-26203-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0324"(messenger rna) sgd:S000004374|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR002300(Aminoacyl-tRNA synthetase, class Ia)|interpro:IPR002302(Leucyl-tRNA synthetase, class Ia, bacterial/mitochondrial)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR009008(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class Ia, editing)|interpro:IPR025709|interpro:IPR015413("Aminoacyl-tRNA synthetase, class I (M)")|ensemblfungi:YLR382C(gene)|ensemblfungi:YLR382C_mRNA(transcript)|go:"GO:0000372"(Group I intron splicing)|go:"GO:0002161"(aminoacyl-tRNA editing activity)|go:"GO:0004823"(leucine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006429"(leucyl-tRNA aminoacylation)|go:"GO:0032543"(mitochondrial translation)|go:"GO:0097157"(pre-mRNA intronic binding)|refseq:NP_013486.3|mint:P11325 - - - - figure legend:Fig. 7|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/09/26 2017/10/09 rogid:EQVBYS0O87N1Je6L+4nFlaM8vQc559292 - - false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P11325 uniprotkb:P03879 intact:EBI-18753|uniprotkb:D6VZ17|ensemblfungi:YLR382C intact:EBI-16420207|ensemblfungi:Q0120|uniprotkb:A0A0A7NYH9|uniprotkb:Q02324|uniprotkb:Q9ZZW6 psi-mi:sylm_yeast(display_long)|uniprotkb:NAM2(gene name)|psi-mi:NAM2(display_short)|uniprotkb:MSL1(gene name synonym)|uniprotkb:YLR382C(locus name)|uniprotkb:L3502.6(orf name)|uniprotkb:Leucyl-tRNA synthetase(gene name synonym) psi-mi:mbi4_yeast(display_long)|uniprotkb:RNA maturase SCbI4(gene name synonym)|uniprotkb:BI4(gene name)|psi-mi:BI4(display_short)|uniprotkb:SCBI4(gene name synonym)|uniprotkb:Q0120(locus name) psi-mi:"MI:0588"(three hybrid) Rho et al. (2000) pubmed:11142386|imex:IM-26203 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-16425328|imex:IM-26203-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000004374|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR002300(Aminoacyl-tRNA synthetase, class Ia)|interpro:IPR002302(Leucyl-tRNA synthetase, class Ia, bacterial/mitochondrial)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR009008(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class Ia, editing)|interpro:IPR025709|interpro:IPR015413("Aminoacyl-tRNA synthetase, class I (M)")|ensemblfungi:YLR382C(gene)|ensemblfungi:YLR382C_mRNA(transcript)|go:"GO:0000372"(Group I intron splicing)|go:"GO:0002161"(aminoacyl-tRNA editing activity)|go:"GO:0004823"(leucine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006429"(leucyl-tRNA aminoacylation)|go:"GO:0032543"(mitochondrial translation)|go:"GO:0097157"(pre-mRNA intronic binding)|refseq:NP_013486.3|mint:P11325 reactome:R-SCE-611105|ensemblfungi:Q0120(gene)|ensemblfungi:Q0120_mRNA(transcript)|go:"GO:0000372"(Group I intron splicing)|go:"GO:0003723"(RNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0090615"(mitochondrial mRNA processing)|refseq:NP_009316.1|interpro:IPR005797(Cytochrome b/b6, N-terminal)|interpro:IPR027387|interpro:IPR016174(Transmembrane di-haem cytochrome)|interpro:IPR027434|interpro:IPR004860(LAGLIDADG DNA endonuclease)|sgd:S000007273 - - - figure legend:Fig. 7|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/09/26 2017/10/09 rogid:EQVBYS0O87N1Je6L+4nFlaM8vQc559292 rogid:lr6bRF/m7gXrA9iTA4kQG7R7TLM559292 - false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)