#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P02930 uniprotkb:P02930 intact:EBI-875614|uniprotkb:Q2M9G5|ensemblbacteria:AAC76071|ensemblbacteria:BAE77091 intact:EBI-875614|uniprotkb:Q2M9G5|ensemblbacteria:AAC76071|ensemblbacteria:BAE77091 psi-mi:tolc_ecoli(display_long)|uniprotkb:tolC(gene name)|psi-mi:tolC(display_short)|uniprotkb:mtcB(gene name synonym)|uniprotkb:mukA(gene name synonym)|uniprotkb:refI(gene name synonym)|uniprotkb:Multidrug efflux pump subunit TolC(gene name synonym)|uniprotkb:Outer membrane factor TolC(gene name synonym)|uniprotkb:colE1-i(gene name synonym)|uniprotkb:toc(gene name synonym)|uniprotkb:weeA(gene name synonym)|uniprotkb:JW5503(locus name)|uniprotkb:b3035(locus name) psi-mi:tolc_ecoli(display_long)|uniprotkb:tolC(gene name)|psi-mi:tolC(display_short)|uniprotkb:mtcB(gene name synonym)|uniprotkb:mukA(gene name synonym)|uniprotkb:refI(gene name synonym)|uniprotkb:Multidrug efflux pump subunit TolC(gene name synonym)|uniprotkb:Outer membrane factor TolC(gene name synonym)|uniprotkb:colE1-i(gene name synonym)|uniprotkb:toc(gene name synonym)|uniprotkb:weeA(gene name synonym)|uniprotkb:JW5503(locus name)|uniprotkb:b3035(locus name) psi-mi:"MI:0114"(x-ray crystallography) Koronakis et al. (2000) pubmed:10879525|doi:10.1038/35016007|imex:IM-24293 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15489704|imex:IM-24293-1|dip:DIP-18079E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_417507.2|refseq:WP_000735278.1|dip:DIP-11007N|ensemblbacteria:AAC76071(transcript)|ensemblbacteria:b3035(gene)|ensemblbacteria:BAE77091(gene)|ensemblbacteria:BAE77091(transcript)|go:"GO:0005216"(ion channel activity)|go:"GO:0009279"(cell outer membrane)|go:"GO:0009636"(response to toxic substance)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0015125"(bile acid transmembrane transporter activity)|go:"GO:0015288"(porin activity)|go:"GO:0015562"(efflux transmembrane transporter activity)|go:"GO:0015721"(bile acid and bile salt transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042930"(enterobactin transport)|go:"GO:0045203"(integral component of cell outer membrane)|go:"GO:0046677"(response to antibiotic)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:1990196"(MacAB-TolC complex)|go:"GO:1990281"(efflux pump complex)|interpro:IPR003423(Outer membrane efflux protein)|interpro:IPR010130(Type I secretion outer membrane protein, TolC)|rcsb pdb:1EK9|rcsb pdb:1TQQ|rcsb pdb:2VDD|rcsb pdb:2VDE|rcsb pdb:2WMZ|rcsb pdb:2XMN|rcsb pdb:5NG5|rcsb pdb:5NIK|rcsb pdb:5NIL|rcsb pdb:5O66|rcsb pdb:5V5S|rcsb pdb:6WXH|rcsb pdb:6WXI refseq:NP_417507.2|refseq:WP_000735278.1|dip:DIP-11007N|ensemblbacteria:AAC76071(transcript)|ensemblbacteria:b3035(gene)|ensemblbacteria:BAE77091(gene)|ensemblbacteria:BAE77091(transcript)|go:"GO:0005216"(ion channel activity)|go:"GO:0009279"(cell outer membrane)|go:"GO:0009636"(response to toxic substance)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0015125"(bile acid transmembrane transporter activity)|go:"GO:0015288"(porin activity)|go:"GO:0015562"(efflux transmembrane transporter activity)|go:"GO:0015721"(bile acid and bile salt transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042930"(enterobactin transport)|go:"GO:0045203"(integral component of cell outer membrane)|go:"GO:0046677"(response to antibiotic)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:1990196"(MacAB-TolC complex)|go:"GO:1990281"(efflux pump complex)|interpro:IPR003423(Outer membrane efflux protein)|interpro:IPR010130(Type I secretion outer membrane protein, TolC)|rcsb pdb:1EK9|rcsb pdb:1TQQ|rcsb pdb:2VDD|rcsb pdb:2VDE|rcsb pdb:2WMZ|rcsb pdb:2XMN|rcsb pdb:5NG5|rcsb pdb:5NIK|rcsb pdb:5NIL|rcsb pdb:5O66|rcsb pdb:5V5S|rcsb pdb:6WXH|rcsb pdb:6WXI psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/04 2017/08/10 rogid:67LQDsYiAt6tDwigzlhM3Pp5+JA83333 rogid:67LQDsYiAt6tDwigzlhM3Pp5+JA83333 rigid:jYYvtdyJteICiGPMzsrlAL9DGbc false sufficient binding region:23-450 sufficient binding region:23-450 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)