#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q7BHI8 uniprotkb:P32592 intact:EBI-11580242 intact:EBI-11509482|ensembl:ENSBTAP00000069668 psi-mi:lka1b_manha(display_long)|uniprotkb:lktA(gene name)|psi-mi:lktA(display_short) psi-mi:itb2_bovin(display_long)|uniprotkb:Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta(gene name synonym)|uniprotkb:Complement receptor C3 subunit beta(gene name synonym)|uniprotkb:ITGB2(gene name)|psi-mi:ITGB2(display_short)|uniprotkb:CD18(gene name synonym) psi-mi:"MI:0892"(solid phase assay) Wang et al. (1998) pubmed:9895270|imex:IM-25970 taxid:75985(manha)|taxid:75985(manha) taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-11509480|imex:IM-25970-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_006248023.1|interpro:IPR018511|interpro:IPR013550(RTX C-terminal)|interpro:IPR018504|interpro:IPR003995(RTX cytolytic toxin, protein A, core, bacterial)|interpro:IPR011049(Serralysin-like metalloprotease, C-terminal)|go:"GO:0001897"(cytolysis by symbiont of host cells)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0044179"(hemolysis in another organism)|go:"GO:0070230"(positive regulation of lymphocyte apoptotic process)|go:"GO:0090729"(toxin activity)|go:"GO:1902512"(positive regulation of apoptotic DNA fragmentation)|interpro:IPR001343(Haemolysin-type calcium-binding region) refseq:NP_786975.1|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0031623"(receptor internalization)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0071404"(cellular response to low-density lipoprotein particle stimulus)|go:"GO:1904996"(positive regulation of leukocyte adhesion to vascular endothelial cell)|interpro:IPR002369(Integrin beta subunit, N-terminal)|interpro:IPR012896(Integrin beta subunit, tail)|interpro:IPR014836(Integrin beta subunit, cytoplasmic)|interpro:IPR015439(Integrin beta-2 subunit, C-terminal)|interpro:IPR015812(Integrin beta subunit)|interpro:IPR016201(Plexin-like fold)|interpro:IPR032695|interpro:IPR033760|interpro:IPR036349|interpro:IPR036465|ensembl:ENSBTAG00000017060(gene)|ensembl:ENSBTAT00000076413(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005925"(focal adhesion)|go:"GO:0006909"(phagocytosis)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008305"(integrin complex)|refseq:XP_015329203.1 - - - figure legend:10|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/01/25 2016/03/01 rogid:W+9TvujfMpik4aAE3sQwYB566Yc75985 rogid:3dRGgMB0xSht1arSD+ZKN5gczSI9913 rigid:T1AjYar3TZG14eeoS/3ma4x03BI false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)