#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
intact:EBI-11703618	uniprotkb:Q12211	rnacentral:URS000045E5E5_559292	intact:EBI-14272|uniprotkb:D6W3F8|ensemblfungi:YPL212C	psi-mi:trna ile uau(display_short)|psi-mi:EBI-11703618(display_long)	psi-mi:pus1_yeast(display_long)|uniprotkb:YPL212C(locus name)|uniprotkb:tRNA-uridine isomerase 1(gene name synonym)|uniprotkb:PUS1(gene name)|psi-mi:PUS1(display_short)|uniprotkb:tRNA pseudouridylate synthase 1(gene name synonym)	psi-mi:"MI:0415"(enzymatic study)	Motorin et al. (1998)	pubmed:9671058|imex:IM-26614	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0414"(enzymatic reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11703613|imex:IM-26614-1	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0325"(transfer rna)	psi-mi:"MI:0326"(protein)	-	refseq:NP_015112.1|sgd:S000006133|ensemblfungi:YPL212C(gene)|ensemblfungi:YPL212C_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006400"(tRNA modification)|go:"GO:0009982"(pseudouridine synthase activity)|go:"GO:0031120"(snRNA pseudouridine synthesis)|go:"GO:1990481"(mRNA pseudouridine synthesis)|interpro:IPR001406(tRNA pseudouridine synthase)|interpro:IPR020094|go:"GO:0031119"(tRNA pseudouridine synthesis)|interpro:IPR020097|interpro:IPR020103|interpro:IPR041708|mint:Q12211|dip:DIP-5344N	-	-	-	figure legend:Fig3A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/05/19	2016/05/19	-	rogid:u8LVhy6qxRakYcjrKYN0QGn34iM559292	-	false	32p radiolabel:?-?|RNA chemical modification:27-27	his tag:n-n	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
intact:EBI-11701147	uniprotkb:Q12211	rnacentral:URS0000241CE9_559292	intact:EBI-14272|uniprotkb:D6W3F8|ensemblfungi:YPL212C	psi-mi:trna val uac(display_short)|psi-mi:EBI-11701147(display_long)	psi-mi:pus1_yeast(display_long)|uniprotkb:YPL212C(locus name)|uniprotkb:tRNA-uridine isomerase 1(gene name synonym)|uniprotkb:PUS1(gene name)|psi-mi:PUS1(display_short)|uniprotkb:tRNA pseudouridylate synthase 1(gene name synonym)	psi-mi:"MI:0415"(enzymatic study)	Motorin et al. (1998)	pubmed:9671058|imex:IM-26614	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0414"(enzymatic reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11703974|imex:IM-26614-3	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0325"(transfer rna)	psi-mi:"MI:0326"(protein)	-	refseq:NP_015112.1|sgd:S000006133|ensemblfungi:YPL212C(gene)|ensemblfungi:YPL212C_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006400"(tRNA modification)|go:"GO:0009982"(pseudouridine synthase activity)|go:"GO:0031120"(snRNA pseudouridine synthesis)|go:"GO:1990481"(mRNA pseudouridine synthesis)|interpro:IPR001406(tRNA pseudouridine synthase)|interpro:IPR020094|go:"GO:0031119"(tRNA pseudouridine synthesis)|interpro:IPR020097|interpro:IPR020103|interpro:IPR041708|mint:Q12211|dip:DIP-5344N	-	-	-	figure legend:Fig3D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/05/19	2016/05/19	-	rogid:u8LVhy6qxRakYcjrKYN0QGn34iM559292	-	false	RNA chemical modification:27-27(17596)|32p radiolabel:?-?|mutation:35-35,37-37	his tag:n-n	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:Q12211	intact:EBI-11704038	intact:EBI-14272|uniprotkb:D6W3F8|ensemblfungi:YPL212C	rnacentral:URS00004A686E_559292	psi-mi:pus1_yeast(display_long)|uniprotkb:YPL212C(locus name)|uniprotkb:tRNA-uridine isomerase 1(gene name synonym)|uniprotkb:PUS1(gene name)|psi-mi:PUS1(display_short)|uniprotkb:tRNA pseudouridylate synthase 1(gene name synonym)	psi-mi:trna trp cca(display_short)|psi-mi:EBI-11704038(display_long)	psi-mi:"MI:0415"(enzymatic study)	Motorin et al. (1998)	pubmed:9671058|imex:IM-26614	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0414"(enzymatic reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11704041|imex:IM-26614-5	-	-	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0325"(transfer rna)	refseq:NP_015112.1|sgd:S000006133|ensemblfungi:YPL212C(gene)|ensemblfungi:YPL212C_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006400"(tRNA modification)|go:"GO:0009982"(pseudouridine synthase activity)|go:"GO:0031120"(snRNA pseudouridine synthesis)|go:"GO:1990481"(mRNA pseudouridine synthesis)|interpro:IPR001406(tRNA pseudouridine synthase)|interpro:IPR020094|go:"GO:0031119"(tRNA pseudouridine synthesis)|interpro:IPR020097|interpro:IPR020103|interpro:IPR041708|mint:Q12211|dip:DIP-5344N	-	-	-	comment:To localizethe pseusouridine, RNA was incubated with CMCT then analysed with primer extension	figure legend:Fig3D, Fig 5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/05/19	2016/05/20	rogid:u8LVhy6qxRakYcjrKYN0QGn34iM559292	-	-	false	his tag:n-n	32p radiolabel:27-28|mutation:34-34|32p radiolabel:?-?	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:2203"(primer extension assay)
intact:EBI-11704896	uniprotkb:Q12211	rnacentral:URS000044E740_559292	intact:EBI-14272|uniprotkb:D6W3F8|ensemblfungi:YPL212C	psi-mi:trna ile uau precursor(display_short)|psi-mi:EBI-11704896(display_long)	psi-mi:pus1_yeast(display_long)|uniprotkb:YPL212C(locus name)|uniprotkb:tRNA-uridine isomerase 1(gene name synonym)|uniprotkb:PUS1(gene name)|psi-mi:PUS1(display_short)|uniprotkb:tRNA pseudouridylate synthase 1(gene name synonym)	psi-mi:"MI:0415"(enzymatic study)	Motorin et al. (1998)	pubmed:9671058|imex:IM-26614	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0414"(enzymatic reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11704938|imex:IM-26614-7	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0325"(transfer rna)	psi-mi:"MI:0326"(protein)	-	refseq:NP_015112.1|sgd:S000006133|ensemblfungi:YPL212C(gene)|ensemblfungi:YPL212C_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006400"(tRNA modification)|go:"GO:0009982"(pseudouridine synthase activity)|go:"GO:0031120"(snRNA pseudouridine synthesis)|go:"GO:1990481"(mRNA pseudouridine synthesis)|interpro:IPR001406(tRNA pseudouridine synthase)|interpro:IPR020094|go:"GO:0031119"(tRNA pseudouridine synthesis)|interpro:IPR020097|interpro:IPR020103|interpro:IPR041708|mint:Q12211|dip:DIP-5344N	-	-	-	figure legend:Fig3A,B, Fig4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/05/19	2016/05/20	-	rogid:u8LVhy6qxRakYcjrKYN0QGn34iM559292	-	false	necessary binding region:34-97|32p radiolabel:?-?|RNA chemical modification:34-34,36-36	his tag:n-n	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
intact:EBI-11705097	uniprotkb:Q12211	rnacentral:URS00003653F5_559292	intact:EBI-14272|uniprotkb:D6W3F8|ensemblfungi:YPL212C	psi-mi:trna tyr gua  precursor(display_short)|psi-mi:EBI-11705097(display_long)	psi-mi:pus1_yeast(display_long)|uniprotkb:YPL212C(locus name)|uniprotkb:tRNA-uridine isomerase 1(gene name synonym)|uniprotkb:PUS1(gene name)|psi-mi:PUS1(display_short)|uniprotkb:tRNA pseudouridylate synthase 1(gene name synonym)	psi-mi:"MI:0415"(enzymatic study)	Motorin et al. (1998)	pubmed:9671058|imex:IM-26614	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0414"(enzymatic reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11705100|imex:IM-26614-9	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0325"(transfer rna)	psi-mi:"MI:0326"(protein)	-	refseq:NP_015112.1|sgd:S000006133|ensemblfungi:YPL212C(gene)|ensemblfungi:YPL212C_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006400"(tRNA modification)|go:"GO:0009982"(pseudouridine synthase activity)|go:"GO:0031120"(snRNA pseudouridine synthesis)|go:"GO:1990481"(mRNA pseudouridine synthesis)|interpro:IPR001406(tRNA pseudouridine synthase)|interpro:IPR020094|go:"GO:0031119"(tRNA pseudouridine synthesis)|interpro:IPR020097|interpro:IPR020103|interpro:IPR041708|mint:Q12211|dip:DIP-5344N	-	-	-	figure legend:Fig3C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/05/19	2016/05/20	-	rogid:u8LVhy6qxRakYcjrKYN0QGn34iM559292	-	false	RNA chemical modification:35-35(17596)|32p radiolabel:?-?	his tag:n-n	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:Q12211	intact:EBI-11701537	intact:EBI-14272|uniprotkb:D6W3F8|ensemblfungi:YPL212C	rnacentral:URS000027E1E5_559292	psi-mi:pus1_yeast(display_long)|uniprotkb:YPL212C(locus name)|uniprotkb:tRNA-uridine isomerase 1(gene name synonym)|uniprotkb:PUS1(gene name)|psi-mi:PUS1(display_short)|uniprotkb:tRNA pseudouridylate synthase 1(gene name synonym)	psi-mi:trna_asp_guc(display_short)|psi-mi:EBI-11701537(display_long)	psi-mi:"MI:0415"(enzymatic study)	Motorin et al. (1998)	pubmed:9671058|imex:IM-26614	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0414"(enzymatic reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11705149|imex:IM-26614-11	-	-	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0325"(transfer rna)	refseq:NP_015112.1|sgd:S000006133|ensemblfungi:YPL212C(gene)|ensemblfungi:YPL212C_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006400"(tRNA modification)|go:"GO:0009982"(pseudouridine synthase activity)|go:"GO:0031120"(snRNA pseudouridine synthesis)|go:"GO:1990481"(mRNA pseudouridine synthesis)|interpro:IPR001406(tRNA pseudouridine synthase)|interpro:IPR020094|go:"GO:0031119"(tRNA pseudouridine synthesis)|interpro:IPR020097|interpro:IPR020103|interpro:IPR041708|mint:Q12211|dip:DIP-5344N	-	-	-	-	figure legend:Fig3D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/05/19	2016/05/20	rogid:u8LVhy6qxRakYcjrKYN0QGn34iM559292	-	-	false	his tag:n-n	32p radiolabel:?-?|RNA chemical modification:27-27|mutation:27-27,28-28,42-42,43-43	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)