#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P11746 uniprotkb:P0CY08 intact:EBI-10528|ensemblfungi:YMR043W|uniprotkb:D6VZL8 intact:EBI-10443|uniprotkb:P01367|uniprotkb:Q6B2C0|uniprotkb:P01368|ensemblfungi:YCL067C|ensemblfungi:YCR039C|uniprotkb:D6VQV2 psi-mi:mcm1_yeast(display_long)|uniprotkb:MCM1(gene name)|psi-mi:MCM1(display_short)|uniprotkb:FUN80(gene name synonym)|uniprotkb:YMR043W(locus name)|uniprotkb:YM9532.08(orf name)|uniprotkb:GRM/PRTF protein(gene name synonym) psi-mi:mtal2_yeast(display_long)|uniprotkb:MATALPHA2(gene name)|psi-mi:MATALPHA2(display_short)|uniprotkb:ALPHA-2(gene name synonym)|uniprotkb:MAT2A(gene name synonym)|uniprotkb:MATAL2(gene name synonym)|uniprotkb:YCR039C(locus name)|uniprotkb:YCR39C(orf name)|uniprotkb:Alpha-2 repressor(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Mead et al. (1996) imex:IM-25507|pubmed:8628280 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-12514986|imex:IM-25507-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0044377"(RNA polymerase II cis-regulatory region sequence-specific DNA binding, bending)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR002100(Transcription factor, MADS-box)|interpro:IPR033897|interpro:IPR036879|go:"GO:0043565"(sequence-specific DNA binding)|rcsb pdb:1MNM|reactome:R-SCE-9031628|ensemblfungi:YMR043W(gene)|ensemblfungi:YMR043W_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001197"(positive regulation of mating-type specific transcription from RNA polymerase II promoter)|go:"GO:0001198"(negative regulation of mating-type specific transcription from RNA polymerase II promoter)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006525"(arginine metabolic process)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0031494"(regulation of mating type switching)|refseq:NP_013757.1|sgd:S000004646|mint:P11746|dip:DIP-72N rcsb pdb:1AKH|rcsb pdb:1APL|rcsb pdb:1K61|rcsb pdb:1LE8|rcsb pdb:1MNM|rcsb pdb:1YRN|ensemblfungi:YCL067C(gene)|ensemblfungi:YCL067C_mRNA(transcript)|ensemblfungi:YCR039C(gene)|ensemblfungi:YCR039C_mRNA(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001198"(negative regulation of mating-type specific transcription from RNA polymerase II promoter)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|interpro:IPR001356(Homeobox)|sgd:S000000635|interpro:IPR009057(Homeodomain-like)|refseq:NP_009866.1|refseq:NP_009868.3 - - caution:This sequence has been withdrawn from Uniprot.|crc64:30CD6A486D7D76CE comment:Mutated MATALPHA2 will coimmunoprecipitate with MCM1 in the presence of DNA, as the protein can still bind to DNA.|figure legend:Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/09/02 2016/09/06 rogid:pwq9qbbdOsicNDlNm5d4z89Jpbk559292 rogid:CVvx1RszIKRLzJWRVUyiWBvISZU559292 rigid:AZ2lZxSM3fm9gm2brKqvwvQ2GiQ false ha tag:?-? his tag:n-n|necessary binding region:114-120 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)