#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P0CY10 uniprotkb:P0CY08 intact:EBI-8492819|uniprotkb:Q06724|uniprotkb:P09091|uniprotkb:D6VR98|uniprotkb:P01366|intact:MINT-717801 intact:EBI-10443|uniprotkb:P01367|uniprotkb:Q6B2C0|uniprotkb:P01368|ensemblfungi:YCL067C|ensemblfungi:YCR039C|uniprotkb:D6VQV2 psi-mi:mata1_yeasx(display_long)|uniprotkb:MATA1(gene name)|psi-mi:MATA1(display_short)|uniprotkb:MAT1A(gene name synonym) psi-mi:mtal2_yeast(display_long)|uniprotkb:MATALPHA2(gene name)|psi-mi:MATALPHA2(display_short)|uniprotkb:ALPHA-2(gene name synonym)|uniprotkb:MAT2A(gene name synonym)|uniprotkb:MATAL2(gene name synonym)|uniprotkb:YCR039C(locus name)|uniprotkb:YCR39C(orf name)|uniprotkb:Alpha-2 repressor(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Ho et al. (1994) pubmed:8137824|imex:IM-25505 taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-12501451|imex:IM-25505-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:1YRN|rcsb pdb:1LE8|rcsb pdb:1F43|rcsb pdb:1AKH|interpro:IPR017970|interpro:IPR009057(Homeodomain-like)|rcsb pdb:1MH3|rcsb pdb:1MH4|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|interpro:IPR001356(Homeobox)|sgd:S000029660 rcsb pdb:1AKH|rcsb pdb:1APL|rcsb pdb:1K61|rcsb pdb:1LE8|rcsb pdb:1MNM|rcsb pdb:1YRN|ensemblfungi:YCL067C(gene)|ensemblfungi:YCL067C_mRNA(transcript)|ensemblfungi:YCR039C(gene)|ensemblfungi:YCR039C_mRNA(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001198"(negative regulation of mating-type specific transcription from RNA polymerase II promoter)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|interpro:IPR001356(Homeobox)|sgd:S000000635|interpro:IPR009057(Homeodomain-like)|refseq:NP_009866.1|refseq:NP_009868.3 - comment:mint|function:"Mating type proteins are sequence specific DNA-binding proteins that act as master switches in yeast differentiation by controlling gene expression in a cell type-specific fashion. Transcriptional corepressor that, in a/alpha diploid cells, binds cooperatively with the ALPHA2 protein to a 21-bp DNA sequence termed the haploid-specific gene (hsg) operator, to repress transcription of haploid-specific genes and of MATALPHA1" caution:This sequence has been withdrawn from Uniprot.|crc64:30CD6A486D7D76CE figure legend:Fig. 5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/08/09 2016/08/26 rogid:ntc/Nk4MqNCamY8xPSWHg9oNYhA4932 rogid:CVvx1RszIKRLzJWRVUyiWBvISZU559292 rigid:lNtPYaXF5ST5KE9hLWw7vxUkJNo false 35s radiolabel:?-? necessary binding region:4-7|mutation disrupting interaction strength:67-67,74-74,81-81,88-88|35s radiolabel:?-? - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) intact:EBI-12514192 uniprotkb:P0CY10 - intact:EBI-8492819|uniprotkb:Q06724|uniprotkb:P09091|uniprotkb:D6VR98|uniprotkb:P01366|intact:MINT-717801 psi-mi:"probe_pmid:8137824"(display_short)|psi-mi:EBI-12514192(display_long) psi-mi:mata1_yeasx(display_long)|uniprotkb:MATA1(gene name)|psi-mi:MATA1(display_short)|uniprotkb:MAT1A(gene name synonym) psi-mi:"MI:0413"(electrophoretic mobility shift assay) Ho et al. (1994) pubmed:8137824|imex:IM-25505 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-12514201|imex:IM-25505-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0681"(double stranded deoxyribonucleic acid) psi-mi:"MI:0326"(protein) - rcsb pdb:1YRN|rcsb pdb:1LE8|rcsb pdb:1F43|rcsb pdb:1AKH|interpro:IPR017970|interpro:IPR009057(Homeodomain-like)|rcsb pdb:1MH3|rcsb pdb:1MH4|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|interpro:IPR001356(Homeobox)|sgd:S000029660 - - comment:mint|function:"Mating type proteins are sequence specific DNA-binding proteins that act as master switches in yeast differentiation by controlling gene expression in a cell type-specific fashion. Transcriptional corepressor that, in a/alpha diploid cells, binds cooperatively with the ALPHA2 protein to a 21-bp DNA sequence termed the haploid-specific gene (hsg) operator, to repress transcription of haploid-specific genes and of MATALPHA1" figure legend:Figs. 4,6,7|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/08/09 2016/09/08 - rogid:ntc/Nk4MqNCamY8xPSWHg9oNYhA4932 - false 35s radiolabel:?-? - - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) intact:EBI-12514192 uniprotkb:P0CY08 - intact:EBI-10443|uniprotkb:P01367|uniprotkb:Q6B2C0|uniprotkb:P01368|ensemblfungi:YCL067C|ensemblfungi:YCR039C|uniprotkb:D6VQV2 psi-mi:"probe_pmid:8137824"(display_short)|psi-mi:EBI-12514192(display_long) psi-mi:mtal2_yeast(display_long)|uniprotkb:MATALPHA2(gene name)|psi-mi:MATALPHA2(display_short)|uniprotkb:ALPHA-2(gene name synonym)|uniprotkb:MAT2A(gene name synonym)|uniprotkb:MATAL2(gene name synonym)|uniprotkb:YCR039C(locus name)|uniprotkb:YCR39C(orf name)|uniprotkb:Alpha-2 repressor(gene name synonym) psi-mi:"MI:0413"(electrophoretic mobility shift assay) Ho et al. (1994) pubmed:8137824|imex:IM-25505 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-12514201|imex:IM-25505-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0681"(double stranded deoxyribonucleic acid) psi-mi:"MI:0326"(protein) - rcsb pdb:1AKH|rcsb pdb:1APL|rcsb pdb:1K61|rcsb pdb:1LE8|rcsb pdb:1MNM|rcsb pdb:1YRN|ensemblfungi:YCL067C(gene)|ensemblfungi:YCL067C_mRNA(transcript)|ensemblfungi:YCR039C(gene)|ensemblfungi:YCR039C_mRNA(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001198"(negative regulation of mating-type specific transcription from RNA polymerase II promoter)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|interpro:IPR001356(Homeobox)|sgd:S000000635|interpro:IPR009057(Homeodomain-like)|refseq:NP_009866.1|refseq:NP_009868.3 - - caution:This sequence has been withdrawn from Uniprot.|crc64:30CD6A486D7D76CE figure legend:Figs. 4,6,7|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/08/09 2016/09/08 - rogid:CVvx1RszIKRLzJWRVUyiWBvISZU559292 - false 35s radiolabel:?-? mutation disrupting interaction strength:81-81|mutation decreasing interaction strength:81-81|mutation disrupting interaction strength:74-74,81-81|mutation disrupting interaction strength:81-81,88-88|mutation decreasing interaction strength:95-95,88-88|mutation disrupting interaction strength:67-67,74-74,81-81,88-88,95-95|mutation disrupting interaction strength:88-88,67-67,74-74,81-81|mutation disrupting interaction strength:67-67,74-74,81-81|mutation disrupting interaction strength:81-81,88-88,74-74|mutation disrupting interaction strength:81-81,88-88,95-95|mutation decreasing interaction strength:33-33|mutation decreasing interaction strength:33-33|mutation decreasing interaction strength:34-34,29-29|mutation disrupting interaction strength:29-29|mutation disrupting interaction strength:29-29,36-36 - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography)