#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q8IV20	uniprotkb:Q8TCU4	intact:EBI-12508070|ensembl:ENSP00000391747|ensembl:ENSP00000317619|uniprotkb:A2A3Z6|uniprotkb:Q8N8X5	intact:EBI-308651|uniprotkb:Q53S05|uniprotkb:Q580Q8|uniprotkb:Q86VP9|uniprotkb:Q9Y4G4|ensembl:ENSP00000482968|uniprotkb:A0A087WZY3	psi-mi:lacc1_human(display_long)|uniprotkb:LACC1(gene name)|psi-mi:LACC1(display_short)|uniprotkb:C13orf31(gene name synonym)|uniprotkb:FAMIN(gene name synonym)|uniprotkb:Fatty acid metabolism-immunity nexus(gene name synonym)|uniprotkb:Adenosine deaminase LACC1(gene name synonym)|uniprotkb:Guanosine phosphorylase LACC1(gene name synonym)|uniprotkb:Laccase domain-containing protein 1(gene name synonym)|uniprotkb:S-methyl-5'-thioadenosine phosphorylase LACC1(gene name synonym)	psi-mi:alms1_human(display_long)|uniprotkb:ALMS1(gene name)|psi-mi:ALMS1(display_short)|uniprotkb:KIAA0328(gene name synonym)	psi-mi:"MI:0004"(affinity chromatography technology)	Cader et al. (2016)	pubmed:27478939|imex:IM-26127	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12508068|imex:IM-26127-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000325686(transcript)|ensembl:ENST00000441843(transcript)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0004000"(adenosine deaminase activity)|go:"GO:0004731"(purine-nucleoside phosphorylase activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006954"(inflammatory response)|go:"GO:0017061"(S-methyl-5-thioadenosine phosphorylase activity)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0045087"(innate immune response)|go:"GO:0047975"(guanosine phosphorylase activity)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:1900542"(regulation of purine nucleotide metabolic process)|interpro:IPR003730(Protein of unknown function DUF152)|interpro:IPR011324(Cytotoxic necrotizing factor-like, catalytic)|interpro:IPR038371|ensembl:ENSG00000179630(gene)|refseq:NP_001121775.1|refseq:NP_694950.2|refseq:XP_005266318.1|refseq:XP_006719829.1|refseq:XP_011533235.1|refseq:XP_011533236.1|refseq:XP_016875883.1	ensembl:ENSG00000116127(gene)|ensembl:ENST00000613296(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0008017"(microtubule binding)|go:"GO:0016197"(endosomal transport)|go:"GO:0046599"(regulation of centriole replication)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR028781|interpro:IPR029299|interpro:IPR040972|mint:Q8TCU4|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_055935.4	-	-	-	figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2016/08/08	2018/04/06	rogid:Y/gCMNfRuvW/8zUT3Fvq2ZR9I8o9606	rogid:e91Hcs947kpQHPVhWAJRtYegdPg9606	rigid:hVqlvzNvaAlh9ruzUf3c55i38xo	false	strep ii tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IV20	uniprotkb:P02545	intact:EBI-12508070|ensembl:ENSP00000391747|ensembl:ENSP00000317619|uniprotkb:A2A3Z6|uniprotkb:Q8N8X5	intact:EBI-351935|uniprotkb:B4DI32|uniprotkb:E7EUI9|uniprotkb:P02546|uniprotkb:Q969I8|uniprotkb:Q96JA2|uniprotkb:D6RAQ3|uniprotkb:Q5I6Y4|uniprotkb:Q5I6Y6|uniprotkb:Q6UYC3|uniprotkb:Q5TCJ2|uniprotkb:Q5TCJ3|uniprotkb:D3DVB0|intact:EBI-28988787|ensembl:ENSP00000355292|ensembl:ENSP00000357283|ensembl:ENSP00000502256|ensembl:ENSP00000506771	psi-mi:lacc1_human(display_long)|uniprotkb:LACC1(gene name)|psi-mi:LACC1(display_short)|uniprotkb:C13orf31(gene name synonym)|uniprotkb:FAMIN(gene name synonym)|uniprotkb:Fatty acid metabolism-immunity nexus(gene name synonym)|uniprotkb:Adenosine deaminase LACC1(gene name synonym)|uniprotkb:Guanosine phosphorylase LACC1(gene name synonym)|uniprotkb:Laccase domain-containing protein 1(gene name synonym)|uniprotkb:S-methyl-5'-thioadenosine phosphorylase LACC1(gene name synonym)	psi-mi:lmna_human(display_long)|uniprotkb:LMNA(gene name)|psi-mi:LMNA(display_short)|uniprotkb:LMN1(gene name synonym)	psi-mi:"MI:0004"(affinity chromatography technology)	Cader et al. (2016)	pubmed:27478939|imex:IM-26127	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12508068|imex:IM-26127-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000325686(transcript)|ensembl:ENST00000441843(transcript)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0004000"(adenosine deaminase activity)|go:"GO:0004731"(purine-nucleoside phosphorylase activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006954"(inflammatory response)|go:"GO:0017061"(S-methyl-5-thioadenosine phosphorylase activity)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0045087"(innate immune response)|go:"GO:0047975"(guanosine phosphorylase activity)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:1900542"(regulation of purine nucleotide metabolic process)|interpro:IPR003730(Protein of unknown function DUF152)|interpro:IPR011324(Cytotoxic necrotizing factor-like, catalytic)|interpro:IPR038371|ensembl:ENSG00000179630(gene)|refseq:NP_001121775.1|refseq:NP_694950.2|refseq:XP_005266318.1|refseq:XP_006719829.1|refseq:XP_011533235.1|refseq:XP_011533236.1|refseq:XP_016875883.1	refseq:NP_005563.1|refseq:NP_733821.1|refseq:NP_733822.1|refseq:NP_001244303.1|refseq:NP_001269553.1|refseq:NP_001269554.1|refseq:NP_001269555.1|ensembl:ENSG00000160789(gene)|ensembl:ENST00000361308(transcript)|ensembl:ENST00000368300(transcript)|ensembl:ENST00000675939(transcript)|ensembl:ENST00000683032(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005638"(lamin filament)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0007517"(muscle organ development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030951"(establishment or maintenance of microtubule cytoskeleton polarity)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055015"(ventricular cardiac muscle cell development)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0072201"(negative regulation of mesenchymal cell proliferation)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0090343"(positive regulation of cell aging)|go:"GO:1900114"(positive regulation of histone H3-K9 trimethylation)|go:"GO:1900180"(regulation of protein localization to nucleus)|go:"GO:1903243"(negative regulation of cardiac muscle hypertrophy in response to stress)|go:"GO:1990683"(DNA double-strand break attachment to nuclear envelope)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001322(Intermediate filament, C-terminal)|interpro:IPR018039|interpro:IPR036415|interpro:IPR039008|mint:P02545|rcsb pdb:1IFR|rcsb pdb:1IVT|rcsb pdb:1X8Y|rcsb pdb:2XV5|rcsb pdb:2YPT|rcsb pdb:3GEF|rcsb pdb:3V4Q|rcsb pdb:3V4W|rcsb pdb:3V5B|rcsb pdb:6GHD|rcsb pdb:6JLB|rcsb pdb:6RPR|rcsb pdb:6SNZ|rcsb pdb:6YF5|rcsb pdb:6YJD|reactome:R-HSA-1221632|reactome:R-HSA-2980766|reactome:R-HSA-2995383|reactome:R-HSA-352238|reactome:R-HSA-381038|reactome:R-HSA-4419969|reactome:R-HSA-6802952|reactome:R-HSA-8862803|ensembl:ENSP00000503633|ensembl:ENST00000682650|ensembl:ENSP00000506904|ensembl:ENST00000677389|ensembl:ENSP00000506771|ensembl:ENSP00000355292|ensembl:ENST00000368299|ensembl:ENSP00000357282|ensembl:ENSP00000357283|ensembl:ENST00000368301|ensembl:ENSP00000357284|ensembl:ENST00000448611|ensembl:ENSP00000395597|ensembl:ENST00000473598|ensembl:ENSP00000421821|ensembl:ENSP00000502256|ensembl:ENST00000676385|ensembl:ENSP00000502091|dip:DIP-32948N|dip:DIP-58162N	-	-	-	figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2016/08/08	2018/04/06	rogid:Y/gCMNfRuvW/8zUT3Fvq2ZR9I8o9606	rogid:OS/QDFLGOD2PElQ6mCpBtk6xh/09606	rigid:hVqlvzNvaAlh9ruzUf3c55i38xo	false	strep ii tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IV20	uniprotkb:I3L2N2	intact:EBI-12508070|ensembl:ENSP00000391747|ensembl:ENSP00000317619|uniprotkb:A2A3Z6|uniprotkb:Q8N8X5	intact:EBI-12508241|ensembl:ENSP00000459797	psi-mi:lacc1_human(display_long)|uniprotkb:LACC1(gene name)|psi-mi:LACC1(display_short)|uniprotkb:C13orf31(gene name synonym)|uniprotkb:FAMIN(gene name synonym)|uniprotkb:Fatty acid metabolism-immunity nexus(gene name synonym)|uniprotkb:Adenosine deaminase LACC1(gene name synonym)|uniprotkb:Guanosine phosphorylase LACC1(gene name synonym)|uniprotkb:Laccase domain-containing protein 1(gene name synonym)|uniprotkb:S-methyl-5'-thioadenosine phosphorylase LACC1(gene name synonym)	psi-mi:i3l2n2_human(display_long)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:"MI:0004"(affinity chromatography technology)	Cader et al. (2016)	pubmed:27478939|imex:IM-26127	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12508068|imex:IM-26127-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000325686(transcript)|ensembl:ENST00000441843(transcript)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0004000"(adenosine deaminase activity)|go:"GO:0004731"(purine-nucleoside phosphorylase activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006954"(inflammatory response)|go:"GO:0017061"(S-methyl-5-thioadenosine phosphorylase activity)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0045087"(innate immune response)|go:"GO:0047975"(guanosine phosphorylase activity)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:1900542"(regulation of purine nucleotide metabolic process)|interpro:IPR003730(Protein of unknown function DUF152)|interpro:IPR011324(Cytotoxic necrotizing factor-like, catalytic)|interpro:IPR038371|ensembl:ENSG00000179630(gene)|refseq:NP_001121775.1|refseq:NP_694950.2|refseq:XP_005266318.1|refseq:XP_006719829.1|refseq:XP_011533235.1|refseq:XP_011533236.1|refseq:XP_016875883.1	ensembl:ENSG00000004975(gene)|ensembl:ENST00000575458(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016235"(aggresome)|go:"GO:0016604"(nuclear body)|go:"GO:0035556"(intracellular signal transduction)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207	-	-	-	figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2016/08/08	2018/04/06	rogid:Y/gCMNfRuvW/8zUT3Fvq2ZR9I8o9606	rogid:DfrNDxQwlqu+J+7qIYfLzILii049606	rigid:hVqlvzNvaAlh9ruzUf3c55i38xo	false	strep ii tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IV20	uniprotkb:Q15007	intact:EBI-12508070|ensembl:ENSP00000391747|ensembl:ENSP00000317619|uniprotkb:A2A3Z6|uniprotkb:Q8N8X5	intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438	psi-mi:lacc1_human(display_long)|uniprotkb:LACC1(gene name)|psi-mi:LACC1(display_short)|uniprotkb:C13orf31(gene name synonym)|uniprotkb:FAMIN(gene name synonym)|uniprotkb:Fatty acid metabolism-immunity nexus(gene name synonym)|uniprotkb:Adenosine deaminase LACC1(gene name synonym)|uniprotkb:Guanosine phosphorylase LACC1(gene name synonym)|uniprotkb:Laccase domain-containing protein 1(gene name synonym)|uniprotkb:S-methyl-5'-thioadenosine phosphorylase LACC1(gene name synonym)	psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym)	psi-mi:"MI:0004"(affinity chromatography technology)	Cader et al. (2016)	pubmed:27478939|imex:IM-26127	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12508068|imex:IM-26127-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000325686(transcript)|ensembl:ENST00000441843(transcript)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0004000"(adenosine deaminase activity)|go:"GO:0004731"(purine-nucleoside phosphorylase activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006954"(inflammatory response)|go:"GO:0017061"(S-methyl-5-thioadenosine phosphorylase activity)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0045087"(innate immune response)|go:"GO:0047975"(guanosine phosphorylase activity)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:1900542"(regulation of purine nucleotide metabolic process)|interpro:IPR003730(Protein of unknown function DUF152)|interpro:IPR011324(Cytotoxic necrotizing factor-like, catalytic)|interpro:IPR038371|ensembl:ENSG00000179630(gene)|refseq:NP_001121775.1|refseq:NP_694950.2|refseq:XP_005266318.1|refseq:XP_006719829.1|refseq:XP_011533235.1|refseq:XP_011533236.1|refseq:XP_016875883.1	refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203	-	-	-	figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2016/08/08	2018/04/06	rogid:Y/gCMNfRuvW/8zUT3Fvq2ZR9I8o9606	rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606	rigid:hVqlvzNvaAlh9ruzUf3c55i38xo	false	strep ii tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IV20	uniprotkb:Q8IWZ8	intact:EBI-12508070|ensembl:ENSP00000391747|ensembl:ENSP00000317619|uniprotkb:A2A3Z6|uniprotkb:Q8N8X5	intact:EBI-2691671|uniprotkb:Q8WWT4|uniprotkb:Q8TCQ4|uniprotkb:Q8WWT5|uniprotkb:Q6P3X9|uniprotkb:Q9NTG3|uniprotkb:O60378|intact:EBI-28984293|ensembl:ENSP00000247001	psi-mi:lacc1_human(display_long)|uniprotkb:LACC1(gene name)|psi-mi:LACC1(display_short)|uniprotkb:C13orf31(gene name synonym)|uniprotkb:FAMIN(gene name synonym)|uniprotkb:Fatty acid metabolism-immunity nexus(gene name synonym)|uniprotkb:Adenosine deaminase LACC1(gene name synonym)|uniprotkb:Guanosine phosphorylase LACC1(gene name synonym)|uniprotkb:Laccase domain-containing protein 1(gene name synonym)|uniprotkb:S-methyl-5'-thioadenosine phosphorylase LACC1(gene name synonym)	psi-mi:sugp1_human(display_long)|uniprotkb:RNA-binding protein RBP(gene name synonym)|uniprotkb:SUGP1(gene name)|psi-mi:SUGP1(display_short)|uniprotkb:SF4(gene name synonym)|uniprotkb:Splicing factor 4(gene name synonym)	psi-mi:"MI:0004"(affinity chromatography technology)	Cader et al. (2016)	pubmed:27478939|imex:IM-26127	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12508068|imex:IM-26127-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000325686(transcript)|ensembl:ENST00000441843(transcript)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0004000"(adenosine deaminase activity)|go:"GO:0004731"(purine-nucleoside phosphorylase activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006954"(inflammatory response)|go:"GO:0017061"(S-methyl-5-thioadenosine phosphorylase activity)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0045087"(innate immune response)|go:"GO:0047975"(guanosine phosphorylase activity)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:1900542"(regulation of purine nucleotide metabolic process)|interpro:IPR003730(Protein of unknown function DUF152)|interpro:IPR011324(Cytotoxic necrotizing factor-like, catalytic)|interpro:IPR038371|ensembl:ENSG00000179630(gene)|refseq:NP_001121775.1|refseq:NP_694950.2|refseq:XP_005266318.1|refseq:XP_006719829.1|refseq:XP_011533235.1|refseq:XP_011533236.1|refseq:XP_016875883.1	refseq:NP_757386.2|ensembl:ENSP00000247001|ensembl:ENST00000588731|ensembl:ENSP00000465413|ensembl:ENSG00000105705(gene)|ensembl:ENST00000247001(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|interpro:IPR000061(SWAP/Surp)|interpro:IPR000467(D111/G-patch)|interpro:IPR035967|interpro:IPR040169|mint:Q8IWZ8|reactome:R-HSA-72163	-	-	-	figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2016/08/08	2018/04/06	rogid:Y/gCMNfRuvW/8zUT3Fvq2ZR9I8o9606	rogid:FLQs/3z1CXsBGCBOWAVeh7HzfuI9606	rigid:hVqlvzNvaAlh9ruzUf3c55i38xo	false	strep ii tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IV20	uniprotkb:Q9UI33-3	intact:EBI-12508070|ensembl:ENSP00000391747|ensembl:ENSP00000317619|uniprotkb:A2A3Z6|uniprotkb:Q8N8X5	intact:EBI-12508116|ensembl:ENSP00000416757	psi-mi:lacc1_human(display_long)|uniprotkb:LACC1(gene name)|psi-mi:LACC1(display_short)|uniprotkb:C13orf31(gene name synonym)|uniprotkb:FAMIN(gene name synonym)|uniprotkb:Fatty acid metabolism-immunity nexus(gene name synonym)|uniprotkb:Adenosine deaminase LACC1(gene name synonym)|uniprotkb:Guanosine phosphorylase LACC1(gene name synonym)|uniprotkb:Laccase domain-containing protein 1(gene name synonym)|uniprotkb:S-methyl-5'-thioadenosine phosphorylase LACC1(gene name synonym)	psi-mi:q9ui33-3(display_long)|uniprotkb:Peripheral nerve sodium channel 5(gene name synonym)|uniprotkb:Sensory neuron sodium channel 2(gene name synonym)|uniprotkb:Sodium channel protein type XI subunit alpha(gene name synonym)|uniprotkb:Voltage-gated sodium channel subunit alpha Nav1.9(gene name synonym)|uniprotkb:hNaN(gene name synonym)|uniprotkb:SCN11A(gene name)|psi-mi:SCN11A(display_short)|uniprotkb:SCN12A(gene name synonym)|uniprotkb:SNS2(gene name synonym)	psi-mi:"MI:0004"(affinity chromatography technology)	Cader et al. (2016)	pubmed:27478939|imex:IM-26127	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12508068|imex:IM-26127-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000325686(transcript)|ensembl:ENST00000441843(transcript)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0004000"(adenosine deaminase activity)|go:"GO:0004731"(purine-nucleoside phosphorylase activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006954"(inflammatory response)|go:"GO:0017061"(S-methyl-5-thioadenosine phosphorylase activity)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0045087"(innate immune response)|go:"GO:0047975"(guanosine phosphorylase activity)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:1900542"(regulation of purine nucleotide metabolic process)|interpro:IPR003730(Protein of unknown function DUF152)|interpro:IPR011324(Cytotoxic necrotizing factor-like, catalytic)|interpro:IPR038371|ensembl:ENSG00000179630(gene)|refseq:NP_001121775.1|refseq:NP_694950.2|refseq:XP_005266318.1|refseq:XP_006719829.1|refseq:XP_011533235.1|refseq:XP_011533236.1|refseq:XP_016875883.1	ensembl:ENSG00000168356(gene)|ensembl:ENST00000456224(transcript)|intact:EBI-2809380(isoform-parent)	-	-	isoform-comment:No experimental confirmation available.	figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2016/08/08	2018/04/06	rogid:Y/gCMNfRuvW/8zUT3Fvq2ZR9I8o9606	rogid:eQqxJLCdQnh0ojM6QDF+MnjtilE9606	rigid:hVqlvzNvaAlh9ruzUf3c55i38xo	false	strep ii tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IV20	uniprotkb:O14929	intact:EBI-12508070|ensembl:ENSP00000391747|ensembl:ENSP00000317619|uniprotkb:A2A3Z6|uniprotkb:Q8N8X5	intact:EBI-2339359|uniprotkb:Q53SU4|uniprotkb:Q53QF0|uniprotkb:Q49A44|uniprotkb:Q6P594|uniprotkb:Q8WWB9|ensembl:ENSP00000264108	psi-mi:lacc1_human(display_long)|uniprotkb:LACC1(gene name)|psi-mi:LACC1(display_short)|uniprotkb:C13orf31(gene name synonym)|uniprotkb:FAMIN(gene name synonym)|uniprotkb:Fatty acid metabolism-immunity nexus(gene name synonym)|uniprotkb:Adenosine deaminase LACC1(gene name synonym)|uniprotkb:Guanosine phosphorylase LACC1(gene name synonym)|uniprotkb:Laccase domain-containing protein 1(gene name synonym)|uniprotkb:S-methyl-5'-thioadenosine phosphorylase LACC1(gene name synonym)	psi-mi:hat1_human(display_long)|uniprotkb:HAT1(gene name)|psi-mi:HAT1(display_short)|uniprotkb:KAT1(gene name synonym)|uniprotkb:Histone acetyltransferase 1(gene name synonym)	psi-mi:"MI:0004"(affinity chromatography technology)	Cader et al. (2016)	pubmed:27478939|imex:IM-26127	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12508068|imex:IM-26127-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000325686(transcript)|ensembl:ENST00000441843(transcript)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0004000"(adenosine deaminase activity)|go:"GO:0004731"(purine-nucleoside phosphorylase activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006954"(inflammatory response)|go:"GO:0017061"(S-methyl-5-thioadenosine phosphorylase activity)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0045087"(innate immune response)|go:"GO:0047975"(guanosine phosphorylase activity)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:1900542"(regulation of purine nucleotide metabolic process)|interpro:IPR003730(Protein of unknown function DUF152)|interpro:IPR011324(Cytotoxic necrotizing factor-like, catalytic)|interpro:IPR038371|ensembl:ENSG00000179630(gene)|refseq:NP_001121775.1|refseq:NP_694950.2|refseq:XP_005266318.1|refseq:XP_006719829.1|refseq:XP_011533235.1|refseq:XP_011533236.1|refseq:XP_016875883.1	refseq:NP_003633.1|dip:DIP-52811N|ensembl:ENSG00000128708(gene)|ensembl:ENST00000264108(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006323"(DNA packaging)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006348"|go:"GO:0006475"(internal protein amino acid acetylation)|go:"GO:0007584"(response to nutrient)|go:"GO:0010485"(H4 histone acetyltransferase activity)|go:"GO:0016363"(nuclear matrix)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043967"(histone H4 acetylation)|interpro:IPR013523(Histone acetyltransferase HAT1, C-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR017380(Histone acetyltransferase type B, catalytic subunit)|interpro:IPR019467|interpro:IPR037113|mint:O14929|rcsb pdb:2P0W|rcsb pdb:6VO5|reactome:R-HSA-3214847	-	-	-	figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2016/08/08	2018/04/06	rogid:Y/gCMNfRuvW/8zUT3Fvq2ZR9I8o9606	rogid:80KgRaid3NeRfAUdTHMQ/r0VuGo9606	rigid:hVqlvzNvaAlh9ruzUf3c55i38xo	false	strep ii tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IV20	uniprotkb:B4DDF7	intact:EBI-12508070|ensembl:ENSP00000391747|ensembl:ENSP00000317619|uniprotkb:A2A3Z6|uniprotkb:Q8N8X5	intact:EBI-9977759	psi-mi:lacc1_human(display_long)|uniprotkb:LACC1(gene name)|psi-mi:LACC1(display_short)|uniprotkb:C13orf31(gene name synonym)|uniprotkb:FAMIN(gene name synonym)|uniprotkb:Fatty acid metabolism-immunity nexus(gene name synonym)|uniprotkb:Adenosine deaminase LACC1(gene name synonym)|uniprotkb:Guanosine phosphorylase LACC1(gene name synonym)|uniprotkb:Laccase domain-containing protein 1(gene name synonym)|uniprotkb:S-methyl-5'-thioadenosine phosphorylase LACC1(gene name synonym)	psi-mi:b4ddf7_human(display_long)	psi-mi:"MI:0004"(affinity chromatography technology)	Cader et al. (2016)	pubmed:27478939|imex:IM-26127	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12508068|imex:IM-26127-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000325686(transcript)|ensembl:ENST00000441843(transcript)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0004000"(adenosine deaminase activity)|go:"GO:0004731"(purine-nucleoside phosphorylase activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006954"(inflammatory response)|go:"GO:0017061"(S-methyl-5-thioadenosine phosphorylase activity)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0045087"(innate immune response)|go:"GO:0047975"(guanosine phosphorylase activity)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:1900542"(regulation of purine nucleotide metabolic process)|interpro:IPR003730(Protein of unknown function DUF152)|interpro:IPR011324(Cytotoxic necrotizing factor-like, catalytic)|interpro:IPR038371|ensembl:ENSG00000179630(gene)|refseq:NP_001121775.1|refseq:NP_694950.2|refseq:XP_005266318.1|refseq:XP_006719829.1|refseq:XP_011533235.1|refseq:XP_011533236.1|refseq:XP_016875883.1	interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR000357(HEAT)|interpro:IPR021133|interpro:IPR031090|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0065003"(protein-containing complex assembly)	-	-	-	figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2016/08/08	2018/04/06	rogid:Y/gCMNfRuvW/8zUT3Fvq2ZR9I8o9606	rogid:ygjoHuYmXHoK0QoLKxuSWxX9XUQ9606	rigid:hVqlvzNvaAlh9ruzUf3c55i38xo	false	strep ii tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IV20	uniprotkb:Q9Y2I1	intact:EBI-12508070|ensembl:ENSP00000391747|ensembl:ENSP00000317619|uniprotkb:A2A3Z6|uniprotkb:Q8N8X5	intact:EBI-2688731|uniprotkb:Q6PIB4|uniprotkb:Q9UEU4|uniprotkb:Q7L8M3|uniprotkb:Q6PGP3|uniprotkb:Q9UFW3|uniprotkb:Q7Z2X6|uniprotkb:Q9UES6|uniprotkb:C9J245|ensembl:ENSP00000339958|ensembl:ENSP00000418232	psi-mi:lacc1_human(display_long)|uniprotkb:LACC1(gene name)|psi-mi:LACC1(display_short)|uniprotkb:C13orf31(gene name synonym)|uniprotkb:FAMIN(gene name synonym)|uniprotkb:Fatty acid metabolism-immunity nexus(gene name synonym)|uniprotkb:Adenosine deaminase LACC1(gene name synonym)|uniprotkb:Guanosine phosphorylase LACC1(gene name synonym)|uniprotkb:Laccase domain-containing protein 1(gene name synonym)|uniprotkb:S-methyl-5'-thioadenosine phosphorylase LACC1(gene name synonym)	psi-mi:nisch_human(display_long)|uniprotkb:IRAS(gene name synonym)|uniprotkb:KIAA0975(gene name synonym)|uniprotkb:Imidazoline receptor 1(gene name synonym)|uniprotkb:Imidazoline receptor antisera-selected protein(gene name synonym)|uniprotkb:Imidazoline-1 receptor(gene name synonym)|uniprotkb:Imidazoline-1 receptor candidate protein(gene name synonym)|uniprotkb:NISCH(gene name)|psi-mi:NISCH(display_short)	psi-mi:"MI:0004"(affinity chromatography technology)	Cader et al. (2016)	pubmed:27478939|imex:IM-26127	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12508068|imex:IM-26127-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000325686(transcript)|ensembl:ENST00000441843(transcript)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0004000"(adenosine deaminase activity)|go:"GO:0004731"(purine-nucleoside phosphorylase activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006954"(inflammatory response)|go:"GO:0017061"(S-methyl-5-thioadenosine phosphorylase activity)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0045087"(innate immune response)|go:"GO:0047975"(guanosine phosphorylase activity)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:1900542"(regulation of purine nucleotide metabolic process)|interpro:IPR003730(Protein of unknown function DUF152)|interpro:IPR011324(Cytotoxic necrotizing factor-like, catalytic)|interpro:IPR038371|ensembl:ENSG00000179630(gene)|refseq:NP_001121775.1|refseq:NP_694950.2|refseq:XP_005266318.1|refseq:XP_006719829.1|refseq:XP_011533235.1|refseq:XP_011533236.1|refseq:XP_016875883.1	refseq:NP_009115.2|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045171"(intercellular bridge)|go:"GO:0048243"(norepinephrine secretion)|go:"GO:0055037"(recycling endosome)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR001683(Phox-like)|interpro:IPR032675|interpro:IPR036871|interpro:IPR037904|mint:Q9Y2I1|rcsb pdb:3P0C|reactome:R-HSA-9013149|reactome:R-HSA-9696264|reactome:R-HSA-9696270|ensembl:ENSG00000010322(gene)|ensembl:ENST00000345716(transcript)|ensembl:ENST00000479054(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0032228"(regulation of synaptic transmission, GABAergic)|refseq:NP_001263222.1|refseq:NP_001263223.1	-	-	-	figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2016/08/08	2018/04/06	rogid:Y/gCMNfRuvW/8zUT3Fvq2ZR9I8o9606	rogid:GuBgG6MUrD5p1hIhGGmrtCjT0jQ9606	rigid:hVqlvzNvaAlh9ruzUf3c55i38xo	false	strep ii tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IV20	uniprotkb:P12277	intact:EBI-12508070|ensembl:ENSP00000391747|ensembl:ENSP00000317619|uniprotkb:A2A3Z6|uniprotkb:Q8N8X5	intact:EBI-357706|uniprotkb:Q2LE07|uniprotkb:A8K236|uniprotkb:B2R5R4|uniprotkb:Q6FG40|uniprotkb:Q9UC66|ensembl:ENSP00000299198	psi-mi:lacc1_human(display_long)|uniprotkb:LACC1(gene name)|psi-mi:LACC1(display_short)|uniprotkb:C13orf31(gene name synonym)|uniprotkb:FAMIN(gene name synonym)|uniprotkb:Fatty acid metabolism-immunity nexus(gene name synonym)|uniprotkb:Adenosine deaminase LACC1(gene name synonym)|uniprotkb:Guanosine phosphorylase LACC1(gene name synonym)|uniprotkb:Laccase domain-containing protein 1(gene name synonym)|uniprotkb:S-methyl-5'-thioadenosine phosphorylase LACC1(gene name synonym)	psi-mi:kcrb_human(display_long)|uniprotkb:CKB(gene name)|psi-mi:CKB(display_short)|uniprotkb:CKBB(gene name synonym)|uniprotkb:Creatine kinase B chain(gene name synonym)|uniprotkb:Brain creatine kinase(gene name synonym)|uniprotkb:Creatine phosphokinase B-type(gene name synonym)	psi-mi:"MI:0004"(affinity chromatography technology)	Cader et al. (2016)	pubmed:27478939|imex:IM-26127	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12508068|imex:IM-26127-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000325686(transcript)|ensembl:ENST00000441843(transcript)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0004000"(adenosine deaminase activity)|go:"GO:0004731"(purine-nucleoside phosphorylase activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006954"(inflammatory response)|go:"GO:0017061"(S-methyl-5-thioadenosine phosphorylase activity)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0045087"(innate immune response)|go:"GO:0047975"(guanosine phosphorylase activity)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:1900542"(regulation of purine nucleotide metabolic process)|interpro:IPR003730(Protein of unknown function DUF152)|interpro:IPR011324(Cytotoxic necrotizing factor-like, catalytic)|interpro:IPR038371|ensembl:ENSG00000179630(gene)|refseq:NP_001121775.1|refseq:NP_694950.2|refseq:XP_005266318.1|refseq:XP_006719829.1|refseq:XP_011533235.1|refseq:XP_011533236.1|refseq:XP_016875883.1	refseq:NP_001814.2|go:"GO:0005829"(cytosol)|ensembl:ENSG00000166165(gene)|ensembl:ENST00000348956(transcript)|go:"GO:0004111"(creatine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0016301"(kinase activity)|go:"GO:0021549"(cerebellum development)|interpro:IPR022413|interpro:IPR022414|interpro:IPR022415|interpro:IPR036802|mint:P12277|rcsb pdb:3B6R|rcsb pdb:3DRB|rcsb pdb:3DRE|rcsb pdb:6V9H|go:"GO:0021762"(substantia nigra development)|go:"GO:0030425"(dendrite)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0046314"(phosphocreatine biosynthetic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000749("ATP:guanido phosphotransferase")|interpro:IPR014746(Glutamine synthetase/guanido kinase, catalytic region)|reactome:R-HSA-71288|reactome:R-HSA-9696264|dip:DIP-52968N	-	-	-	figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2016/08/08	2018/04/06	rogid:Y/gCMNfRuvW/8zUT3Fvq2ZR9I8o9606	rogid:WLRnU8sRUfJQoaPY0edGi9xiR+g9606	rigid:hVqlvzNvaAlh9ruzUf3c55i38xo	false	strep ii tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IV20	uniprotkb:B3KWI4	intact:EBI-12508070|ensembl:ENSP00000391747|ensembl:ENSP00000317619|uniprotkb:A2A3Z6|uniprotkb:Q8N8X5	intact:EBI-12508233	psi-mi:lacc1_human(display_long)|uniprotkb:LACC1(gene name)|psi-mi:LACC1(display_short)|uniprotkb:C13orf31(gene name synonym)|uniprotkb:FAMIN(gene name synonym)|uniprotkb:Fatty acid metabolism-immunity nexus(gene name synonym)|uniprotkb:Adenosine deaminase LACC1(gene name synonym)|uniprotkb:Guanosine phosphorylase LACC1(gene name synonym)|uniprotkb:Laccase domain-containing protein 1(gene name synonym)|uniprotkb:S-methyl-5'-thioadenosine phosphorylase LACC1(gene name synonym)	psi-mi:b3kwi4_human(display_long)	psi-mi:"MI:0004"(affinity chromatography technology)	Cader et al. (2016)	pubmed:27478939|imex:IM-26127	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12508068|imex:IM-26127-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000325686(transcript)|ensembl:ENST00000441843(transcript)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0004000"(adenosine deaminase activity)|go:"GO:0004731"(purine-nucleoside phosphorylase activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006954"(inflammatory response)|go:"GO:0017061"(S-methyl-5-thioadenosine phosphorylase activity)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0045087"(innate immune response)|go:"GO:0047975"(guanosine phosphorylase activity)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:1900542"(regulation of purine nucleotide metabolic process)|interpro:IPR003730(Protein of unknown function DUF152)|interpro:IPR011324(Cytotoxic necrotizing factor-like, catalytic)|interpro:IPR038371|ensembl:ENSG00000179630(gene)|refseq:NP_001121775.1|refseq:NP_694950.2|refseq:XP_005266318.1|refseq:XP_006719829.1|refseq:XP_011533235.1|refseq:XP_011533236.1|refseq:XP_016875883.1	go:"GO:0016021"(integral component of membrane)|refseq:NP_570843.2|interpro:IPR032675|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)	-	-	-	figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2016/08/08	2018/04/06	rogid:Y/gCMNfRuvW/8zUT3Fvq2ZR9I8o9606	rogid:+7LOYDDek3GJ9Ix8kCp06KPQWnw9606	rigid:hVqlvzNvaAlh9ruzUf3c55i38xo	false	strep ii tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IV20	uniprotkb:Q9HAW4-2	intact:EBI-12508070|ensembl:ENSP00000391747|ensembl:ENSP00000317619|uniprotkb:A2A3Z6|uniprotkb:Q8N8X5	intact:EBI-12508227|ensembl:ENSP00000362317	psi-mi:lacc1_human(display_long)|uniprotkb:LACC1(gene name)|psi-mi:LACC1(display_short)|uniprotkb:C13orf31(gene name synonym)|uniprotkb:FAMIN(gene name synonym)|uniprotkb:Fatty acid metabolism-immunity nexus(gene name synonym)|uniprotkb:Adenosine deaminase LACC1(gene name synonym)|uniprotkb:Guanosine phosphorylase LACC1(gene name synonym)|uniprotkb:Laccase domain-containing protein 1(gene name synonym)|uniprotkb:S-methyl-5'-thioadenosine phosphorylase LACC1(gene name synonym)	psi-mi:q9haw4-2(display_long)|uniprotkb:CLSPN(gene name)|psi-mi:CLSPN(display_short)	psi-mi:"MI:0004"(affinity chromatography technology)	Cader et al. (2016)	pubmed:27478939|imex:IM-26127	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12508068|imex:IM-26127-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000325686(transcript)|ensembl:ENST00000441843(transcript)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0004000"(adenosine deaminase activity)|go:"GO:0004731"(purine-nucleoside phosphorylase activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006954"(inflammatory response)|go:"GO:0017061"(S-methyl-5-thioadenosine phosphorylase activity)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0045087"(innate immune response)|go:"GO:0047975"(guanosine phosphorylase activity)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:1900542"(regulation of purine nucleotide metabolic process)|interpro:IPR003730(Protein of unknown function DUF152)|interpro:IPR011324(Cytotoxic necrotizing factor-like, catalytic)|interpro:IPR038371|ensembl:ENSG00000179630(gene)|refseq:NP_001121775.1|refseq:NP_694950.2|refseq:XP_005266318.1|refseq:XP_006719829.1|refseq:XP_011533235.1|refseq:XP_011533236.1|refseq:XP_016875883.1	intact:EBI-1369377(isoform-parent)|uniprotkb:Q9HAW4-2(isoform-parent)|ensembl:ENSG00000092853(gene)|ensembl:ENST00000373220(transcript)	-	-	-	figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2016/08/08	2018/04/06	rogid:Y/gCMNfRuvW/8zUT3Fvq2ZR9I8o9606	rogid:P2FA8VdkHo4sEISZQhL040uW1Mc9606	rigid:hVqlvzNvaAlh9ruzUf3c55i38xo	false	strep ii tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IV20	uniprotkb:P00338-3	intact:EBI-12508070|ensembl:ENSP00000391747|ensembl:ENSP00000317619|uniprotkb:A2A3Z6|uniprotkb:Q8N8X5	intact:EBI-10195200|ensembl:ENSP00000445175|ensembl:ENSP00000500603	psi-mi:lacc1_human(display_long)|uniprotkb:LACC1(gene name)|psi-mi:LACC1(display_short)|uniprotkb:C13orf31(gene name synonym)|uniprotkb:FAMIN(gene name synonym)|uniprotkb:Fatty acid metabolism-immunity nexus(gene name synonym)|uniprotkb:Adenosine deaminase LACC1(gene name synonym)|uniprotkb:Guanosine phosphorylase LACC1(gene name synonym)|uniprotkb:Laccase domain-containing protein 1(gene name synonym)|uniprotkb:S-methyl-5'-thioadenosine phosphorylase LACC1(gene name synonym)	psi-mi:p00338-3(display_long)|uniprotkb:Cell proliferation-inducing gene 19 protein(gene name synonym)|uniprotkb:LDH muscle subunit(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-59(gene name synonym)|uniprotkb:PIG19(orf name)|uniprotkb:LDHA(gene name)|psi-mi:LDHA(display_short)	psi-mi:"MI:0004"(affinity chromatography technology)	Cader et al. (2016)	pubmed:27478939|imex:IM-26127	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12508068|imex:IM-26127-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000325686(transcript)|ensembl:ENST00000441843(transcript)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0004000"(adenosine deaminase activity)|go:"GO:0004731"(purine-nucleoside phosphorylase activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006954"(inflammatory response)|go:"GO:0017061"(S-methyl-5-thioadenosine phosphorylase activity)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0045087"(innate immune response)|go:"GO:0047975"(guanosine phosphorylase activity)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:1900542"(regulation of purine nucleotide metabolic process)|interpro:IPR003730(Protein of unknown function DUF152)|interpro:IPR011324(Cytotoxic necrotizing factor-like, catalytic)|interpro:IPR038371|ensembl:ENSG00000179630(gene)|refseq:NP_001121775.1|refseq:NP_694950.2|refseq:XP_005266318.1|refseq:XP_006719829.1|refseq:XP_011533235.1|refseq:XP_011533236.1|refseq:XP_016875883.1	ensembl:ENSG00000134333(gene)|ensembl:ENSG00000288299(gene)|ensembl:ENST00000540430(transcript)|ensembl:ENST00000673007(transcript)|uniprotkb:P00338-3(isoform-parent)|intact:EBI-372327(isoform-parent)	-	-	-	figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2016/08/08	2018/04/06	rogid:Y/gCMNfRuvW/8zUT3Fvq2ZR9I8o9606	rogid:D6W0TxH0yH6hTaZ8MvBh4soTNeY9606	rigid:hVqlvzNvaAlh9ruzUf3c55i38xo	false	strep ii tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IV20	uniprotkb:E7DVW5	intact:EBI-12508070|ensembl:ENSP00000391747|ensembl:ENSP00000317619|uniprotkb:A2A3Z6|uniprotkb:Q8N8X5	intact:EBI-12508211	psi-mi:lacc1_human(display_long)|uniprotkb:LACC1(gene name)|psi-mi:LACC1(display_short)|uniprotkb:C13orf31(gene name synonym)|uniprotkb:FAMIN(gene name synonym)|uniprotkb:Fatty acid metabolism-immunity nexus(gene name synonym)|uniprotkb:Adenosine deaminase LACC1(gene name synonym)|uniprotkb:Guanosine phosphorylase LACC1(gene name synonym)|uniprotkb:Laccase domain-containing protein 1(gene name synonym)|uniprotkb:S-methyl-5'-thioadenosine phosphorylase LACC1(gene name synonym)	psi-mi:e7dvw5_human(display_long)|uniprotkb:FABP5(gene name)|psi-mi:FABP5(display_short)	psi-mi:"MI:0004"(affinity chromatography technology)	Cader et al. (2016)	pubmed:27478939|imex:IM-26127	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12508068|imex:IM-26127-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000325686(transcript)|ensembl:ENST00000441843(transcript)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0004000"(adenosine deaminase activity)|go:"GO:0004731"(purine-nucleoside phosphorylase activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006954"(inflammatory response)|go:"GO:0017061"(S-methyl-5-thioadenosine phosphorylase activity)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0045087"(innate immune response)|go:"GO:0047975"(guanosine phosphorylase activity)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:1900542"(regulation of purine nucleotide metabolic process)|interpro:IPR003730(Protein of unknown function DUF152)|interpro:IPR011324(Cytotoxic necrotizing factor-like, catalytic)|interpro:IPR038371|ensembl:ENSG00000179630(gene)|refseq:NP_001121775.1|refseq:NP_694950.2|refseq:XP_005266318.1|refseq:XP_006719829.1|refseq:XP_011533235.1|refseq:XP_011533236.1|refseq:XP_016875883.1	go:"GO:0001972"(retinoic acid binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006656"(phosphatidylcholine biosynthetic process)|go:"GO:0010829"(negative regulation of glucose transmembrane transport)|go:"GO:0014069"(postsynaptic density)|go:"GO:0031392"(regulation of prostaglandin biosynthetic process)|go:"GO:0035360"(positive regulation of peroxisome proliferator activated receptor signaling pathway)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0099178"(regulation of retrograde trans-synaptic signaling by endocanabinoid)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|refseq:NP_001435.1|interpro:IPR012674(Calycin)|interpro:IPR000463(Cytosolic fatty-acid binding)|interpro:IPR031259|interpro:IPR000566(Lipocalin-related protein and Bos/Can/Equ allergen)	-	-	-	figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2016/08/08	2018/04/06	rogid:Y/gCMNfRuvW/8zUT3Fvq2ZR9I8o9606	rogid:vxp81/mezHcm5oo27QOmAM8Y5dI9606	rigid:hVqlvzNvaAlh9ruzUf3c55i38xo	false	strep ii tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IV20	uniprotkb:Q13228	intact:EBI-12508070|ensembl:ENSP00000391747|ensembl:ENSP00000317619|uniprotkb:A2A3Z6|uniprotkb:Q8N8X5	intact:EBI-711619|uniprotkb:A6NML9|uniprotkb:A6PVW9|uniprotkb:B2RDR3|uniprotkb:Q96GX7|uniprotkb:B4DKP6|uniprotkb:Q49AQ8|uniprotkb:B4E1F3|ensembl:ENSP00000357861	psi-mi:lacc1_human(display_long)|uniprotkb:LACC1(gene name)|psi-mi:LACC1(display_short)|uniprotkb:C13orf31(gene name synonym)|uniprotkb:FAMIN(gene name synonym)|uniprotkb:Fatty acid metabolism-immunity nexus(gene name synonym)|uniprotkb:Adenosine deaminase LACC1(gene name synonym)|uniprotkb:Guanosine phosphorylase LACC1(gene name synonym)|uniprotkb:Laccase domain-containing protein 1(gene name synonym)|uniprotkb:S-methyl-5'-thioadenosine phosphorylase LACC1(gene name synonym)	psi-mi:sbp1_human(display_long)|uniprotkb:SELENBP1(gene name)|psi-mi:SELENBP1(display_short)|uniprotkb:SBP(gene name synonym)|uniprotkb:56 kDa selenium-binding protein(gene name synonym)|uniprotkb:Selenium-binding protein 1(gene name synonym)	psi-mi:"MI:0004"(affinity chromatography technology)	Cader et al. (2016)	pubmed:27478939|imex:IM-26127	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12508068|imex:IM-26127-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000325686(transcript)|ensembl:ENST00000441843(transcript)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0004000"(adenosine deaminase activity)|go:"GO:0004731"(purine-nucleoside phosphorylase activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006954"(inflammatory response)|go:"GO:0017061"(S-methyl-5-thioadenosine phosphorylase activity)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0045087"(innate immune response)|go:"GO:0047975"(guanosine phosphorylase activity)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:1900542"(regulation of purine nucleotide metabolic process)|interpro:IPR003730(Protein of unknown function DUF152)|interpro:IPR011324(Cytotoxic necrotizing factor-like, catalytic)|interpro:IPR038371|ensembl:ENSG00000179630(gene)|refseq:NP_001121775.1|refseq:NP_694950.2|refseq:XP_005266318.1|refseq:XP_006719829.1|refseq:XP_011533235.1|refseq:XP_011533236.1|refseq:XP_016875883.1	refseq:NP_003935.2|refseq:NP_001245218.1|refseq:NP_001245217.1|ensembl:ENSG00000143416(gene)|ensembl:ENST00000368868(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005615"(extracellular space)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0008430"(selenium binding)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0018549"(methanethiol oxidase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR008826(Selenium-binding protein)	-	-	-	figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2016/08/08	2018/04/06	rogid:Y/gCMNfRuvW/8zUT3Fvq2ZR9I8o9606	rogid:PqHTrxV3+3S/4C428UI+2jl6omo9606	rigid:hVqlvzNvaAlh9ruzUf3c55i38xo	false	strep ii tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IV20	uniprotkb:P16152	intact:EBI-12508070|ensembl:ENSP00000391747|ensembl:ENSP00000317619|uniprotkb:A2A3Z6|uniprotkb:Q8N8X5	intact:EBI-351348|uniprotkb:Q3LHW8|uniprotkb:B2RBZ7|ensembl:ENSP00000290349|uniprotkb:B4DFK7	psi-mi:lacc1_human(display_long)|uniprotkb:LACC1(gene name)|psi-mi:LACC1(display_short)|uniprotkb:C13orf31(gene name synonym)|uniprotkb:FAMIN(gene name synonym)|uniprotkb:Fatty acid metabolism-immunity nexus(gene name synonym)|uniprotkb:Adenosine deaminase LACC1(gene name synonym)|uniprotkb:Guanosine phosphorylase LACC1(gene name synonym)|uniprotkb:Laccase domain-containing protein 1(gene name synonym)|uniprotkb:S-methyl-5'-thioadenosine phosphorylase LACC1(gene name synonym)	psi-mi:cbr1_human(display_long)|uniprotkb:SDR21C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 21C member 1(gene name synonym)|uniprotkb:CBR1(gene name)|psi-mi:CBR1(display_short)|uniprotkb:CBR(gene name synonym)|uniprotkb:CRN(gene name synonym)|uniprotkb:NADPH-dependent carbonyl reductase 1(gene name synonym)|uniprotkb:"Prostaglandin-E(2) 9-reductase"(gene name synonym)|uniprotkb:Prostaglandin 9-ketoreductase(gene name synonym)|uniprotkb:"15-hydroxyprostaglandin dehydrogenase [NADP(+)]"(gene name synonym)|uniprotkb:20-beta-hydroxysteroid dehydrogenase(gene name synonym)	psi-mi:"MI:0004"(affinity chromatography technology)	Cader et al. (2016)	pubmed:27478939|imex:IM-26127	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12508068|imex:IM-26127-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000325686(transcript)|ensembl:ENST00000441843(transcript)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0004000"(adenosine deaminase activity)|go:"GO:0004731"(purine-nucleoside phosphorylase activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006954"(inflammatory response)|go:"GO:0017061"(S-methyl-5-thioadenosine phosphorylase activity)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0045087"(innate immune response)|go:"GO:0047975"(guanosine phosphorylase activity)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:1900542"(regulation of purine nucleotide metabolic process)|interpro:IPR003730(Protein of unknown function DUF152)|interpro:IPR011324(Cytotoxic necrotizing factor-like, catalytic)|interpro:IPR038371|ensembl:ENSG00000179630(gene)|refseq:NP_001121775.1|refseq:NP_694950.2|refseq:XP_005266318.1|refseq:XP_006719829.1|refseq:XP_011533235.1|refseq:XP_011533236.1|refseq:XP_016875883.1	refseq:NP_001748.1|ensembl:ENSG00000159228(gene)|ensembl:ENST00000290349(transcript)|go:"GO:0004090"("carbonyl reductase (NADPH) activity")|go:"GO:0005829"(cytosol)|go:"GO:0016655"("oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor")|go:"GO:0017144"|go:"GO:0019371"(cyclooxygenase pathway)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0042373"(vitamin K metabolic process)|go:"GO:0047020"("15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity")|go:"GO:0047021"("15-hydroxyprostaglandin dehydrogenase (NADP+) activity")|go:"GO:0050221"(prostaglandin-E2 9-reductase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903561"(extracellular vesicle)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|mint:P16152|rcsb pdb:1WMA|rcsb pdb:2PFG|rcsb pdb:3BHI|rcsb pdb:3BHJ|rcsb pdb:3BHM|rcsb pdb:4Z3D|reactome:R-HSA-2162123|refseq:NP_001273718.1|dip:DIP-33136N	-	-	-	figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2016/08/08	2018/04/06	rogid:Y/gCMNfRuvW/8zUT3Fvq2ZR9I8o9606	rogid:ROzNiYne9nXfvDC9Hi3Ni6M7ILA9606	rigid:hVqlvzNvaAlh9ruzUf3c55i38xo	false	strep ii tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IV20	uniprotkb:L0R5A1	intact:EBI-12508070|ensembl:ENSP00000391747|ensembl:ENSP00000317619|uniprotkb:A2A3Z6|uniprotkb:Q8N8X5	intact:EBI-12508207	psi-mi:lacc1_human(display_long)|uniprotkb:LACC1(gene name)|psi-mi:LACC1(display_short)|uniprotkb:C13orf31(gene name synonym)|uniprotkb:FAMIN(gene name synonym)|uniprotkb:Fatty acid metabolism-immunity nexus(gene name synonym)|uniprotkb:Adenosine deaminase LACC1(gene name synonym)|uniprotkb:Guanosine phosphorylase LACC1(gene name synonym)|uniprotkb:Laccase domain-containing protein 1(gene name synonym)|uniprotkb:S-methyl-5'-thioadenosine phosphorylase LACC1(gene name synonym)	psi-mi:l0r5a1_human(display_long)|uniprotkb:CSF2RB(gene name)|psi-mi:CSF2RB(display_short)	psi-mi:"MI:0004"(affinity chromatography technology)	Cader et al. (2016)	pubmed:27478939|imex:IM-26127	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12508068|imex:IM-26127-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000325686(transcript)|ensembl:ENST00000441843(transcript)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0004000"(adenosine deaminase activity)|go:"GO:0004731"(purine-nucleoside phosphorylase activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006954"(inflammatory response)|go:"GO:0017061"(S-methyl-5-thioadenosine phosphorylase activity)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0045087"(innate immune response)|go:"GO:0047975"(guanosine phosphorylase activity)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:1900542"(regulation of purine nucleotide metabolic process)|interpro:IPR003730(Protein of unknown function DUF152)|interpro:IPR011324(Cytotoxic necrotizing factor-like, catalytic)|interpro:IPR038371|ensembl:ENSG00000179630(gene)|refseq:NP_001121775.1|refseq:NP_694950.2|refseq:XP_005266318.1|refseq:XP_006719829.1|refseq:XP_011533235.1|refseq:XP_011533236.1|refseq:XP_016875883.1	-	-	-	-	figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2016/08/08	2018/04/06	rogid:Y/gCMNfRuvW/8zUT3Fvq2ZR9I8o9606	rogid:sxgCXc57ohfN2F2IDd003lCx8mo9606	rigid:hVqlvzNvaAlh9ruzUf3c55i38xo	false	strep ii tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IV20	uniprotkb:P43487	intact:EBI-12508070|ensembl:ENSP00000391747|ensembl:ENSP00000317619|uniprotkb:A2A3Z6|uniprotkb:Q8N8X5	intact:EBI-1032909|uniprotkb:Q53EY3|ensembl:ENSP00000327583	psi-mi:lacc1_human(display_long)|uniprotkb:LACC1(gene name)|psi-mi:LACC1(display_short)|uniprotkb:C13orf31(gene name synonym)|uniprotkb:FAMIN(gene name synonym)|uniprotkb:Fatty acid metabolism-immunity nexus(gene name synonym)|uniprotkb:Adenosine deaminase LACC1(gene name synonym)|uniprotkb:Guanosine phosphorylase LACC1(gene name synonym)|uniprotkb:Laccase domain-containing protein 1(gene name synonym)|uniprotkb:S-methyl-5'-thioadenosine phosphorylase LACC1(gene name synonym)	psi-mi:rang_human(display_long)|uniprotkb:RANBP1(gene name)|psi-mi:RANBP1(display_short)|uniprotkb:Ran-binding protein 1(gene name synonym)	psi-mi:"MI:0004"(affinity chromatography technology)	Cader et al. (2016)	pubmed:27478939|imex:IM-26127	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12508068|imex:IM-26127-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000325686(transcript)|ensembl:ENST00000441843(transcript)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0004000"(adenosine deaminase activity)|go:"GO:0004731"(purine-nucleoside phosphorylase activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006954"(inflammatory response)|go:"GO:0017061"(S-methyl-5-thioadenosine phosphorylase activity)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0045087"(innate immune response)|go:"GO:0047975"(guanosine phosphorylase activity)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:1900542"(regulation of purine nucleotide metabolic process)|interpro:IPR003730(Protein of unknown function DUF152)|interpro:IPR011324(Cytotoxic necrotizing factor-like, catalytic)|interpro:IPR038371|ensembl:ENSG00000179630(gene)|refseq:NP_001121775.1|refseq:NP_694950.2|refseq:XP_005266318.1|refseq:XP_006719829.1|refseq:XP_011533235.1|refseq:XP_011533236.1|refseq:XP_016875883.1	refseq:NP_002873.1|ensembl:ENSG00000099901(gene)|ensembl:ENST00000331821(transcript)|go:"GO:0005092"(GDP-dissociation inhibitor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0031267"(small GTPase binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046604"(positive regulation of mitotic centrosome separation)|go:"GO:0046907"(intracellular transport)|interpro:IPR000156(Ran Binding Protein 1)|interpro:IPR011993(Pleckstrin homology-type)|rcsb pdb:1K5D|rcsb pdb:1K5G|reactome:R-HSA-165054|refseq:NP_001265568.1|refseq:NP_001265569.1|dip:DIP-35058N	-	-	-	figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2016/08/08	2018/04/06	rogid:Y/gCMNfRuvW/8zUT3Fvq2ZR9I8o9606	rogid:OWndphaUCDSO3+MGhJqcuQo2Lk09606	rigid:hVqlvzNvaAlh9ruzUf3c55i38xo	false	strep ii tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IV20	uniprotkb:Q6N093	intact:EBI-12508070|ensembl:ENSP00000391747|ensembl:ENSP00000317619|uniprotkb:A2A3Z6|uniprotkb:Q8N8X5	intact:EBI-12508197	psi-mi:lacc1_human(display_long)|uniprotkb:LACC1(gene name)|psi-mi:LACC1(display_short)|uniprotkb:C13orf31(gene name synonym)|uniprotkb:FAMIN(gene name synonym)|uniprotkb:Fatty acid metabolism-immunity nexus(gene name synonym)|uniprotkb:Adenosine deaminase LACC1(gene name synonym)|uniprotkb:Guanosine phosphorylase LACC1(gene name synonym)|uniprotkb:Laccase domain-containing protein 1(gene name synonym)|uniprotkb:S-methyl-5'-thioadenosine phosphorylase LACC1(gene name synonym)	psi-mi:q6n093_human(display_long)|uniprotkb:DKFZp686I04196(gene name)|psi-mi:DKFZp686I04196(display_short)	psi-mi:"MI:0004"(affinity chromatography technology)	Cader et al. (2016)	pubmed:27478939|imex:IM-26127	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12508068|imex:IM-26127-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000325686(transcript)|ensembl:ENST00000441843(transcript)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0004000"(adenosine deaminase activity)|go:"GO:0004731"(purine-nucleoside phosphorylase activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006954"(inflammatory response)|go:"GO:0017061"(S-methyl-5-thioadenosine phosphorylase activity)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0045087"(innate immune response)|go:"GO:0047975"(guanosine phosphorylase activity)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:1900542"(regulation of purine nucleotide metabolic process)|interpro:IPR003730(Protein of unknown function DUF152)|interpro:IPR011324(Cytotoxic necrotizing factor-like, catalytic)|interpro:IPR038371|ensembl:ENSG00000179630(gene)|refseq:NP_001121775.1|refseq:NP_694950.2|refseq:XP_005266318.1|refseq:XP_006719829.1|refseq:XP_011533235.1|refseq:XP_011533236.1|refseq:XP_016875883.1	go:"GO:0016020"(membrane)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR036179	-	-	-	figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2016/08/08	2018/04/06	rogid:Y/gCMNfRuvW/8zUT3Fvq2ZR9I8o9606	rogid:+6qTjfas5N+VvSca0hU+IKFyIfw9606	rigid:hVqlvzNvaAlh9ruzUf3c55i38xo	false	strep ii tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IV20	uniprotkb:P07476	intact:EBI-12508070|ensembl:ENSP00000391747|ensembl:ENSP00000317619|uniprotkb:A2A3Z6|uniprotkb:Q8N8X5	intact:EBI-11307220|uniprotkb:Q5T7P4|intact:EBI-28974501|ensembl:ENSP00000357753	psi-mi:lacc1_human(display_long)|uniprotkb:LACC1(gene name)|psi-mi:LACC1(display_short)|uniprotkb:C13orf31(gene name synonym)|uniprotkb:FAMIN(gene name synonym)|uniprotkb:Fatty acid metabolism-immunity nexus(gene name synonym)|uniprotkb:Adenosine deaminase LACC1(gene name synonym)|uniprotkb:Guanosine phosphorylase LACC1(gene name synonym)|uniprotkb:Laccase domain-containing protein 1(gene name synonym)|uniprotkb:S-methyl-5'-thioadenosine phosphorylase LACC1(gene name synonym)	psi-mi:invo_human(display_long)|uniprotkb:IVL(gene name)|psi-mi:IVL(display_short)	psi-mi:"MI:0004"(affinity chromatography technology)	Cader et al. (2016)	pubmed:27478939|imex:IM-26127	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12508068|imex:IM-26127-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000325686(transcript)|ensembl:ENST00000441843(transcript)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0004000"(adenosine deaminase activity)|go:"GO:0004731"(purine-nucleoside phosphorylase activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006954"(inflammatory response)|go:"GO:0017061"(S-methyl-5-thioadenosine phosphorylase activity)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0045087"(innate immune response)|go:"GO:0047975"(guanosine phosphorylase activity)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:1900542"(regulation of purine nucleotide metabolic process)|interpro:IPR003730(Protein of unknown function DUF152)|interpro:IPR011324(Cytotoxic necrotizing factor-like, catalytic)|interpro:IPR038371|ensembl:ENSG00000179630(gene)|refseq:NP_001121775.1|refseq:NP_694950.2|refseq:XP_005266318.1|refseq:XP_006719829.1|refseq:XP_011533235.1|refseq:XP_011533236.1|refseq:XP_016875883.1	ensembl:ENSP00000357753|refseq:NP_005538.2|ensembl:ENSG00000163207(gene)|ensembl:ENST00000368764(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0010224"(response to UV-B)|go:"GO:0016604"(nuclear body)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0018153"("isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine")|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0031424"(keratinization)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000354(Involucrin repeat)|interpro:IPR002360(Involucrin)|interpro:IPR019571|interpro:IPR019743|mint:P07476|rcsb pdb:1EU0|reactome:R-HSA-6809371	-	-	-	figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2016/08/08	2018/04/06	rogid:Y/gCMNfRuvW/8zUT3Fvq2ZR9I8o9606	rogid:1ZHgB7J+AXcC45RMlCMkoEwUta49606	rigid:hVqlvzNvaAlh9ruzUf3c55i38xo	false	strep ii tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IV20	uniprotkb:P36952	intact:EBI-12508070|ensembl:ENSP00000391747|ensembl:ENSP00000317619|uniprotkb:A2A3Z6|uniprotkb:Q8N8X5	intact:EBI-2371394|uniprotkb:B2R6Y4|uniprotkb:Q6N0B4|uniprotkb:Q8WW89|ensembl:ENSP00000372221	psi-mi:lacc1_human(display_long)|uniprotkb:LACC1(gene name)|psi-mi:LACC1(display_short)|uniprotkb:C13orf31(gene name synonym)|uniprotkb:FAMIN(gene name synonym)|uniprotkb:Fatty acid metabolism-immunity nexus(gene name synonym)|uniprotkb:Adenosine deaminase LACC1(gene name synonym)|uniprotkb:Guanosine phosphorylase LACC1(gene name synonym)|uniprotkb:Laccase domain-containing protein 1(gene name synonym)|uniprotkb:S-methyl-5'-thioadenosine phosphorylase LACC1(gene name synonym)	psi-mi:spb5_human(display_long)|uniprotkb:SERPINB5(gene name)|psi-mi:SERPINB5(display_short)|uniprotkb:PI5(gene name synonym)|uniprotkb:Peptidase inhibitor 5(gene name synonym)|uniprotkb:Maspin(gene name synonym)	psi-mi:"MI:0004"(affinity chromatography technology)	Cader et al. (2016)	pubmed:27478939|imex:IM-26127	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12508068|imex:IM-26127-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000325686(transcript)|ensembl:ENST00000441843(transcript)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0004000"(adenosine deaminase activity)|go:"GO:0004731"(purine-nucleoside phosphorylase activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006954"(inflammatory response)|go:"GO:0017061"(S-methyl-5-thioadenosine phosphorylase activity)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0045087"(innate immune response)|go:"GO:0047975"(guanosine phosphorylase activity)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:1900542"(regulation of purine nucleotide metabolic process)|interpro:IPR003730(Protein of unknown function DUF152)|interpro:IPR011324(Cytotoxic necrotizing factor-like, catalytic)|interpro:IPR038371|ensembl:ENSG00000179630(gene)|refseq:NP_001121775.1|refseq:NP_694950.2|refseq:XP_005266318.1|refseq:XP_006719829.1|refseq:XP_011533235.1|refseq:XP_011533236.1|refseq:XP_016875883.1	refseq:NP_002630.2|ensembl:ENSG00000206075(gene)|ensembl:ENST00000382771(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0050678"(regulation of epithelial cell proliferation)|go:"GO:0060512"(prostate gland morphogenesis)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR000240(Serpin B9 and maspin)|interpro:IPR023795|interpro:IPR023796|interpro:IPR033836|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|mint:P36952|rcsb pdb:1WZ9|rcsb pdb:1XQG|rcsb pdb:1XQJ|rcsb pdb:1XU8	-	-	-	figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2016/08/08	2018/04/06	rogid:Y/gCMNfRuvW/8zUT3Fvq2ZR9I8o9606	rogid:p2g5mTsqtSjgS73Zvoy64BV5Zes9606	rigid:hVqlvzNvaAlh9ruzUf3c55i38xo	false	strep ii tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IV20	uniprotkb:Q13263	intact:EBI-12508070|ensembl:ENSP00000391747|ensembl:ENSP00000317619|uniprotkb:A2A3Z6|uniprotkb:Q8N8X5	intact:EBI-78139|uniprotkb:O00677|ensembl:ENSP00000253024|uniprotkb:Q7Z632|uniprotkb:Q93040|uniprotkb:Q96IM1	psi-mi:lacc1_human(display_long)|uniprotkb:LACC1(gene name)|psi-mi:LACC1(display_short)|uniprotkb:C13orf31(gene name synonym)|uniprotkb:FAMIN(gene name synonym)|uniprotkb:Fatty acid metabolism-immunity nexus(gene name synonym)|uniprotkb:Adenosine deaminase LACC1(gene name synonym)|uniprotkb:Guanosine phosphorylase LACC1(gene name synonym)|uniprotkb:Laccase domain-containing protein 1(gene name synonym)|uniprotkb:S-methyl-5'-thioadenosine phosphorylase LACC1(gene name synonym)	psi-mi:tif1b_human(display_long)|uniprotkb:TRIM28(gene name)|psi-mi:TRIM28(display_short)|uniprotkb:KAP1(gene name synonym)|uniprotkb:RNF96(gene name synonym)|uniprotkb:TIF1B(gene name synonym)|uniprotkb:Tripartite motif-containing protein 28(gene name synonym)|uniprotkb:Nuclear corepressor KAP-1(gene name synonym)|uniprotkb:KRAB-associated protein 1(gene name synonym)|uniprotkb:KRAB-interacting protein 1(gene name synonym)|uniprotkb:RING finger protein 96(gene name synonym)|uniprotkb:E3 SUMO-protein ligase TRIM28(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-beta(gene name synonym)	psi-mi:"MI:0004"(affinity chromatography technology)	Cader et al. (2016)	pubmed:27478939|imex:IM-26127	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12508068|imex:IM-26127-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000325686(transcript)|ensembl:ENST00000441843(transcript)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0004000"(adenosine deaminase activity)|go:"GO:0004731"(purine-nucleoside phosphorylase activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006954"(inflammatory response)|go:"GO:0017061"(S-methyl-5-thioadenosine phosphorylase activity)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0045087"(innate immune response)|go:"GO:0047975"(guanosine phosphorylase activity)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:1900542"(regulation of purine nucleotide metabolic process)|interpro:IPR003730(Protein of unknown function DUF152)|interpro:IPR011324(Cytotoxic necrotizing factor-like, catalytic)|interpro:IPR038371|ensembl:ENSG00000179630(gene)|refseq:NP_001121775.1|refseq:NP_694950.2|refseq:XP_005266318.1|refseq:XP_006719829.1|refseq:XP_011533235.1|refseq:XP_011533236.1|refseq:XP_016875883.1	ensembl:ENSG00000130726(gene)|ensembl:ENST00000253024(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007566"(embryo implantation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035851"(Krueppel-associated box domain binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043045"(DNA methylation involved in embryo development)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0060028"(convergent extension involved in axis elongation)|go:"GO:0060669"(embryonic placenta morphogenesis)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:0090309"(positive regulation of DNA methylation-dependent heterochromatin assembly)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|rcsb pdb:6QAJ|rcsb pdb:6QU1|reactome:R-HSA-212436|reactome:R-HSA-3899300|reactome:R-HSA-9609690|go:"GO:1901536"(negative regulation of DNA demethylation)|go:"GO:1902187"|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000653"(regulation of genetic imprinting)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|interpro:IPR037373|interpro:IPR042713|mint:Q13263|rcsb pdb:1FP0|rcsb pdb:2RO1|rcsb pdb:2YVR|rcsb pdb:6H3A|rcsb pdb:6I9H|refseq:NP_005753.1|dip:DIP-30891N	-	-	-	figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2016/08/08	2018/04/06	rogid:Y/gCMNfRuvW/8zUT3Fvq2ZR9I8o9606	rogid:/yXCDGKUyyYnArOLyfzx6uPR9QY9606	rigid:hVqlvzNvaAlh9ruzUf3c55i38xo	false	strep ii tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IV20	uniprotkb:A4D1U5	intact:EBI-12508070|ensembl:ENSP00000391747|ensembl:ENSP00000317619|uniprotkb:A2A3Z6|uniprotkb:Q8N8X5	intact:EBI-12508181	psi-mi:lacc1_human(display_long)|uniprotkb:LACC1(gene name)|psi-mi:LACC1(display_short)|uniprotkb:C13orf31(gene name synonym)|uniprotkb:FAMIN(gene name synonym)|uniprotkb:Fatty acid metabolism-immunity nexus(gene name synonym)|uniprotkb:Adenosine deaminase LACC1(gene name synonym)|uniprotkb:Guanosine phosphorylase LACC1(gene name synonym)|uniprotkb:Laccase domain-containing protein 1(gene name synonym)|uniprotkb:S-methyl-5'-thioadenosine phosphorylase LACC1(gene name synonym)	psi-mi:a4d1u5_human(display_long)|uniprotkb:FLJ10842(gene name)|psi-mi:FLJ10842(display_short)|uniprotkb:MULK(gene name synonym)|uniprotkb:hCG_39451(orf name)|uniprotkb:tcag7.330(orf name)	psi-mi:"MI:0004"(affinity chromatography technology)	Cader et al. (2016)	pubmed:27478939|imex:IM-26127	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12508068|imex:IM-26127-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000325686(transcript)|ensembl:ENST00000441843(transcript)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0004000"(adenosine deaminase activity)|go:"GO:0004731"(purine-nucleoside phosphorylase activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006954"(inflammatory response)|go:"GO:0017061"(S-methyl-5-thioadenosine phosphorylase activity)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0045087"(innate immune response)|go:"GO:0047975"(guanosine phosphorylase activity)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:1900542"(regulation of purine nucleotide metabolic process)|interpro:IPR003730(Protein of unknown function DUF152)|interpro:IPR011324(Cytotoxic necrotizing factor-like, catalytic)|interpro:IPR038371|ensembl:ENSG00000179630(gene)|refseq:NP_001121775.1|refseq:NP_694950.2|refseq:XP_005266318.1|refseq:XP_006719829.1|refseq:XP_011533235.1|refseq:XP_011533236.1|refseq:XP_016875883.1	go:"GO:0001729"(ceramide kinase activity)|go:"GO:0003951"(NAD+ kinase activity)|go:"GO:0004143"(diacylglycerol kinase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0016020"(membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0047620"(acylglycerol kinase activity)|refseq:NP_060708.1|refseq:XP_011514699.1|interpro:IPR001206(Diacylglycerol kinase, catalytic region)|interpro:IPR016064(ATP-NAD kinase, PpnK-type)|interpro:IPR017438(ATP-NAD kinase, PpnK-type, alpha/beta)	-	-	-	figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2016/08/08	2018/04/06	rogid:Y/gCMNfRuvW/8zUT3Fvq2ZR9I8o9606	rogid:aUz/aYnkviiUE/ijNEddfOQmjZQ9606	rigid:hVqlvzNvaAlh9ruzUf3c55i38xo	false	strep ii tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IV20	uniprotkb:K7EIG1	intact:EBI-12508070|ensembl:ENSP00000391747|ensembl:ENSP00000317619|uniprotkb:A2A3Z6|uniprotkb:Q8N8X5	intact:EBI-12508166|ensembl:ENSP00000464732	psi-mi:lacc1_human(display_long)|uniprotkb:LACC1(gene name)|psi-mi:LACC1(display_short)|uniprotkb:C13orf31(gene name synonym)|uniprotkb:FAMIN(gene name synonym)|uniprotkb:Fatty acid metabolism-immunity nexus(gene name synonym)|uniprotkb:Adenosine deaminase LACC1(gene name synonym)|uniprotkb:Guanosine phosphorylase LACC1(gene name synonym)|uniprotkb:Laccase domain-containing protein 1(gene name synonym)|uniprotkb:S-methyl-5'-thioadenosine phosphorylase LACC1(gene name synonym)	psi-mi:k7eig1_human(display_long)|uniprotkb:CLUH(gene name)|psi-mi:CLUH(display_short)	psi-mi:"MI:0004"(affinity chromatography technology)	Cader et al. (2016)	pubmed:27478939|imex:IM-26127	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12508068|imex:IM-26127-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000325686(transcript)|ensembl:ENST00000441843(transcript)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0004000"(adenosine deaminase activity)|go:"GO:0004731"(purine-nucleoside phosphorylase activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006954"(inflammatory response)|go:"GO:0017061"(S-methyl-5-thioadenosine phosphorylase activity)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0045087"(innate immune response)|go:"GO:0047975"(guanosine phosphorylase activity)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:1900542"(regulation of purine nucleotide metabolic process)|interpro:IPR003730(Protein of unknown function DUF152)|interpro:IPR011324(Cytotoxic necrotizing factor-like, catalytic)|interpro:IPR038371|ensembl:ENSG00000179630(gene)|refseq:NP_001121775.1|refseq:NP_694950.2|refseq:XP_005266318.1|refseq:XP_006719829.1|refseq:XP_011533235.1|refseq:XP_011533236.1|refseq:XP_016875883.1	ensembl:ENSG00000132361(gene)|ensembl:ENST00000575014(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0048312"(intracellular distribution of mitochondria)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR023231|interpro:IPR025697|interpro:IPR027523|interpro:IPR028275|interpro:IPR033646	-	-	-	figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2016/08/08	2018/04/06	rogid:Y/gCMNfRuvW/8zUT3Fvq2ZR9I8o9606	rogid:944DSX7wGR6xTSvKXicRBKVeDrs9606	rigid:hVqlvzNvaAlh9ruzUf3c55i38xo	false	strep ii tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IV20	uniprotkb:B7Z3V1	intact:EBI-12508070|ensembl:ENSP00000391747|ensembl:ENSP00000317619|uniprotkb:A2A3Z6|uniprotkb:Q8N8X5	intact:EBI-12508149	psi-mi:lacc1_human(display_long)|uniprotkb:LACC1(gene name)|psi-mi:LACC1(display_short)|uniprotkb:C13orf31(gene name synonym)|uniprotkb:FAMIN(gene name synonym)|uniprotkb:Fatty acid metabolism-immunity nexus(gene name synonym)|uniprotkb:Adenosine deaminase LACC1(gene name synonym)|uniprotkb:Guanosine phosphorylase LACC1(gene name synonym)|uniprotkb:Laccase domain-containing protein 1(gene name synonym)|uniprotkb:S-methyl-5'-thioadenosine phosphorylase LACC1(gene name synonym)	psi-mi:b7z3v1_human(display_long)	psi-mi:"MI:0004"(affinity chromatography technology)	Cader et al. (2016)	pubmed:27478939|imex:IM-26127	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12508068|imex:IM-26127-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000325686(transcript)|ensembl:ENST00000441843(transcript)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0004000"(adenosine deaminase activity)|go:"GO:0004731"(purine-nucleoside phosphorylase activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006954"(inflammatory response)|go:"GO:0017061"(S-methyl-5-thioadenosine phosphorylase activity)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0045087"(innate immune response)|go:"GO:0047975"(guanosine phosphorylase activity)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:1900542"(regulation of purine nucleotide metabolic process)|interpro:IPR003730(Protein of unknown function DUF152)|interpro:IPR011324(Cytotoxic necrotizing factor-like, catalytic)|interpro:IPR038371|ensembl:ENSG00000179630(gene)|refseq:NP_001121775.1|refseq:NP_694950.2|refseq:XP_005266318.1|refseq:XP_006719829.1|refseq:XP_011533235.1|refseq:XP_011533236.1|refseq:XP_016875883.1	go:"GO:0005524"(ATP binding)|go:"GO:0008556"(P-type potassium transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR023299|interpro:IPR018303|interpro:IPR023298|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR005775(ATPase, P-type cation exchange, alpha subunit, eukaryotic)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR023214|interpro:IPR044492|interpro:IPR036412	-	-	-	figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2016/08/08	2018/04/06	rogid:Y/gCMNfRuvW/8zUT3Fvq2ZR9I8o9606	rogid:pr2tcG3ByFJzAjutV9gQghP7dp49606	rigid:hVqlvzNvaAlh9ruzUf3c55i38xo	false	strep ii tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IV20	uniprotkb:Q16531	intact:EBI-12508070|ensembl:ENSP00000391747|ensembl:ENSP00000317619|uniprotkb:A2A3Z6|uniprotkb:Q8N8X5	intact:EBI-350322|uniprotkb:A6NG77|uniprotkb:O15176|uniprotkb:Q13289|ensembl:ENSP00000301764|ensembl:ENSP00000506223|ensembl:ENSP00000506685|uniprotkb:Q58F96|uniprotkb:B2R648|uniprotkb:B4DG00	psi-mi:lacc1_human(display_long)|uniprotkb:LACC1(gene name)|psi-mi:LACC1(display_short)|uniprotkb:C13orf31(gene name synonym)|uniprotkb:FAMIN(gene name synonym)|uniprotkb:Fatty acid metabolism-immunity nexus(gene name synonym)|uniprotkb:Adenosine deaminase LACC1(gene name synonym)|uniprotkb:Guanosine phosphorylase LACC1(gene name synonym)|uniprotkb:Laccase domain-containing protein 1(gene name synonym)|uniprotkb:S-methyl-5'-thioadenosine phosphorylase LACC1(gene name synonym)	psi-mi:ddb1_human(display_long)|uniprotkb:DDB1(gene name)|psi-mi:DDB1(display_short)|uniprotkb:Damage-specific DNA-binding protein 1(gene name synonym)|uniprotkb:UV-damaged DNA-binding factor(gene name synonym)|uniprotkb:DDB p127 subunit(gene name synonym)|uniprotkb:DNA damage-binding protein a(gene name synonym)|uniprotkb:UV-damaged DNA-binding protein 1(gene name synonym)|uniprotkb:Xeroderma pigmentosum group E-complementing protein(gene name synonym)|uniprotkb:XPE-binding factor(gene name synonym)|uniprotkb:HBV X-associated protein 1(gene name synonym)|uniprotkb:XAP1(gene name synonym)	psi-mi:"MI:0004"(affinity chromatography technology)	Cader et al. (2016)	pubmed:27478939|imex:IM-26127	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12508068|imex:IM-26127-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000325686(transcript)|ensembl:ENST00000441843(transcript)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0004000"(adenosine deaminase activity)|go:"GO:0004731"(purine-nucleoside phosphorylase activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006954"(inflammatory response)|go:"GO:0017061"(S-methyl-5-thioadenosine phosphorylase activity)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0045087"(innate immune response)|go:"GO:0047975"(guanosine phosphorylase activity)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:1900542"(regulation of purine nucleotide metabolic process)|interpro:IPR003730(Protein of unknown function DUF152)|interpro:IPR011324(Cytotoxic necrotizing factor-like, catalytic)|interpro:IPR038371|ensembl:ENSG00000179630(gene)|refseq:NP_001121775.1|refseq:NP_694950.2|refseq:XP_005266318.1|refseq:XP_006719829.1|refseq:XP_011533235.1|refseq:XP_011533236.1|refseq:XP_016875883.1	refseq:NP_001914.3|rcsb pdb:3I89|rcsb pdb:3I8C|rcsb pdb:3I8E|rcsb pdb:4A08|rcsb pdb:4A09|rcsb pdb:4A0A|rcsb pdb:4A0B|rcsb pdb:4A0K|rcsb pdb:4A0L|rcsb pdb:4A11|rcsb pdb:4CI1|rcsb pdb:4CI2|rcsb pdb:4CI3|rcsb pdb:4E54|rcsb pdb:4E5Z|rcsb pdb:4TZ4|rcsb pdb:5FQD|rcsb pdb:5HXB|rcsb pdb:5JK7|rcsb pdb:5V3O|rcsb pdb:6BN7|ensembl:ENSG00000167986(gene)|ensembl:ENST00000301764(transcript)|ensembl:ENST00000680367(transcript)|ensembl:ENST00000681803(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030674"(protein-macromolecule adaptor activity)|rcsb pdb:6BN8|rcsb pdb:6BN9|rcsb pdb:6BNB|rcsb pdb:6BOY|rcsb pdb:6DSZ|rcsb pdb:6FCV|rcsb pdb:6H0F|rcsb pdb:6H0G|rcsb pdb:6PAI|rcsb pdb:6Q0R|rcsb pdb:6Q0V|rcsb pdb:6Q0W|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|rcsb pdb:6R92|rcsb pdb:6SJ7|rcsb pdb:6TD3|rcsb pdb:6UD7|rcsb pdb:6UE5|rcsb pdb:6UML|rcsb pdb:6XK9|rcsb pdb:7LPS|reactome:R-HSA-110314|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-8951664|go:"GO:0031464"(Cul4A-RING E3 ubiquitin ligase complex)|go:"GO:0031465"(Cul4B-RING E3 ubiquitin ligase complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046726"(positive regulation by virus of viral protein levels in host cell)|go:"GO:0048511"(rhythmic process)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070914"(UV-damage excision repair)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1901990"(regulation of mitotic cell cycle phase transition)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|interpro:IPR004871(Cleavage and polyadenylation specificity factor, A subunit, C-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018846|interpro:IPR031297|interpro:IPR036322|mint:Q16531|rcsb pdb:2B5L|rcsb pdb:2B5M|rcsb pdb:2B5N|rcsb pdb:2HYE|rcsb pdb:3E0C|rcsb pdb:3EI1|rcsb pdb:3EI2|rcsb pdb:3EI3|rcsb pdb:3EI4|rcsb pdb:3I7H|rcsb pdb:3I7K|rcsb pdb:3I7L|rcsb pdb:3I7N|rcsb pdb:3I7O|rcsb pdb:3I7P|dip:DIP-430N	-	-	-	figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2016/08/08	2018/04/06	rogid:Y/gCMNfRuvW/8zUT3Fvq2ZR9I8o9606	rogid:qgMjZqvlsbGIGn2qM/pnLTtGyGM9606	rigid:hVqlvzNvaAlh9ruzUf3c55i38xo	false	strep ii tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IV20	uniprotkb:Q6FHQ0	intact:EBI-12508070|ensembl:ENSP00000391747|ensembl:ENSP00000317619|uniprotkb:A2A3Z6|uniprotkb:Q8N8X5	intact:EBI-1057040	psi-mi:lacc1_human(display_long)|uniprotkb:LACC1(gene name)|psi-mi:LACC1(display_short)|uniprotkb:C13orf31(gene name synonym)|uniprotkb:FAMIN(gene name synonym)|uniprotkb:Fatty acid metabolism-immunity nexus(gene name synonym)|uniprotkb:Adenosine deaminase LACC1(gene name synonym)|uniprotkb:Guanosine phosphorylase LACC1(gene name synonym)|uniprotkb:Laccase domain-containing protein 1(gene name synonym)|uniprotkb:S-methyl-5'-thioadenosine phosphorylase LACC1(gene name synonym)	psi-mi:q6fhq0_human(display_long)|uniprotkb:RBBP7(gene name)|psi-mi:RBBP7(display_short)|uniprotkb:hCG_20110(orf name)	psi-mi:"MI:0004"(affinity chromatography technology)	Cader et al. (2016)	pubmed:27478939|imex:IM-26127	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12508068|imex:IM-26127-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000325686(transcript)|ensembl:ENST00000441843(transcript)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0004000"(adenosine deaminase activity)|go:"GO:0004731"(purine-nucleoside phosphorylase activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006954"(inflammatory response)|go:"GO:0017061"(S-methyl-5-thioadenosine phosphorylase activity)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0045087"(innate immune response)|go:"GO:0047975"(guanosine phosphorylase activity)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:1900542"(regulation of purine nucleotide metabolic process)|interpro:IPR003730(Protein of unknown function DUF152)|interpro:IPR011324(Cytotoxic necrotizing factor-like, catalytic)|interpro:IPR038371|ensembl:ENSG00000179630(gene)|refseq:NP_001121775.1|refseq:NP_694950.2|refseq:XP_005266318.1|refseq:XP_006719829.1|refseq:XP_011533235.1|refseq:XP_011533236.1|refseq:XP_016875883.1	refseq:NP_002884.1|interpro:IPR020472|interpro:IPR022052|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR001680(WD40 repeat)|interpro:IPR019775|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0016581"(NuRD complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0048545"(response to steroid hormone)|interpro:IPR036322	-	-	-	figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2016/08/08	2018/04/06	rogid:Y/gCMNfRuvW/8zUT3Fvq2ZR9I8o9606	rogid:qANLG0ui7jm3Uy4+IRnxR8Kir7c9606	rigid:hVqlvzNvaAlh9ruzUf3c55i38xo	false	strep ii tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IV20	uniprotkb:Q96ST3	intact:EBI-12508070|ensembl:ENSP00000391747|ensembl:ENSP00000317619|uniprotkb:A2A3Z6|uniprotkb:Q8N8X5	intact:EBI-347218|uniprotkb:Q8N8N4|uniprotkb:Q8NC83|uniprotkb:Q8WV18|uniprotkb:Q96L98|uniprotkb:Q9UFQ1|intact:EBI-28985143|ensembl:ENSP00000353622|ensembl:ENSP00000378402|ensembl:ENSP00000378403|uniprotkb:B2RNS5	psi-mi:lacc1_human(display_long)|uniprotkb:LACC1(gene name)|psi-mi:LACC1(display_short)|uniprotkb:C13orf31(gene name synonym)|uniprotkb:FAMIN(gene name synonym)|uniprotkb:Fatty acid metabolism-immunity nexus(gene name synonym)|uniprotkb:Adenosine deaminase LACC1(gene name synonym)|uniprotkb:Guanosine phosphorylase LACC1(gene name synonym)|uniprotkb:Laccase domain-containing protein 1(gene name synonym)|uniprotkb:S-methyl-5'-thioadenosine phosphorylase LACC1(gene name synonym)	psi-mi:sin3a_human(display_long)|uniprotkb:SIN3A(gene name)|psi-mi:SIN3A(display_short)|uniprotkb:Transcriptional corepressor Sin3a(gene name synonym)|uniprotkb:Histone deacetylase complex subunit Sin3a(gene name synonym)	psi-mi:"MI:0004"(affinity chromatography technology)	Cader et al. (2016)	pubmed:27478939|imex:IM-26127	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12508068|imex:IM-26127-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000325686(transcript)|ensembl:ENST00000441843(transcript)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0004000"(adenosine deaminase activity)|go:"GO:0004731"(purine-nucleoside phosphorylase activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006954"(inflammatory response)|go:"GO:0017061"(S-methyl-5-thioadenosine phosphorylase activity)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0045087"(innate immune response)|go:"GO:0047975"(guanosine phosphorylase activity)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:1900542"(regulation of purine nucleotide metabolic process)|interpro:IPR003730(Protein of unknown function DUF152)|interpro:IPR011324(Cytotoxic necrotizing factor-like, catalytic)|interpro:IPR038371|ensembl:ENSG00000179630(gene)|refseq:NP_001121775.1|refseq:NP_694950.2|refseq:XP_005266318.1|refseq:XP_006719829.1|refseq:XP_011533235.1|refseq:XP_011533236.1|refseq:XP_016875883.1	refseq:XP_006720528.1|ensembl:ENSG00000169375(gene)|ensembl:ENST00000360439(transcript)|ensembl:ENST00000394947(transcript)|ensembl:ENST00000394949(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000776"(kinetochore)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006260"(DNA replication)|go:"GO:0006476"(protein deacetylation)|go:"GO:0007568"(aging)|go:"GO:0010817"(regulation of hormone levels)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0021895"(cerebral cortex neuron differentiation)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0031937"(obsolete positive regulation of chromatin silencing)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043619"(regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048511"(rhythmic process)|go:"GO:0051595"(response to methylglyoxal)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|go:"GO:1901675"(negative regulation of histone H3-K27 acetylation)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|interpro:IPR003822(Paired amphipathic helix)|interpro:IPR013194(Histone deacetylase interacting)|interpro:IPR031693|interpro:IPR036600|interpro:IPR037969|interpro:IPR039774|mint:Q96ST3|reactome:R-HSA-3899300|reactome:R-HSA-400206|reactome:R-HSA-427413|reactome:R-HSA-8936459|reactome:R-HSA-9022538|reactome:R-HSA-9022692|reactome:R-HSA-9022699|reactome:R-HSA-9022702|rcsb pdb:1PO4|reactome:R-HSA-9615017|reactome:R-HSA-9707564|reactome:R-HSA-983231|refseq:XP_006720529.1|refseq:XP_006720530.1|refseq:NP_001138829.1|refseq:NP_001138830.1|refseq:NP_056292.1|ensembl:ENSP00000353622|ensembl:ENSP00000378402|ensembl:ENSP00000378403|dip:DIP-31515N	-	-	-	figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2016/08/08	2018/04/06	rogid:Y/gCMNfRuvW/8zUT3Fvq2ZR9I8o9606	rogid:pO/FziDcMNQRfy6ePi6eNKELXVM9606	rigid:hVqlvzNvaAlh9ruzUf3c55i38xo	false	strep ii tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IV20	uniprotkb:E9PG19	intact:EBI-12508070|ensembl:ENSP00000391747|ensembl:ENSP00000317619|uniprotkb:A2A3Z6|uniprotkb:Q8N8X5	intact:EBI-12508139|ensembl:ENSP00000386987	psi-mi:lacc1_human(display_long)|uniprotkb:LACC1(gene name)|psi-mi:LACC1(display_short)|uniprotkb:C13orf31(gene name synonym)|uniprotkb:FAMIN(gene name synonym)|uniprotkb:Fatty acid metabolism-immunity nexus(gene name synonym)|uniprotkb:Adenosine deaminase LACC1(gene name synonym)|uniprotkb:Guanosine phosphorylase LACC1(gene name synonym)|uniprotkb:Laccase domain-containing protein 1(gene name synonym)|uniprotkb:S-methyl-5'-thioadenosine phosphorylase LACC1(gene name synonym)	psi-mi:e9pg19_human(display_long)|uniprotkb:FCHSD2(gene name)|psi-mi:FCHSD2(display_short)	psi-mi:"MI:0004"(affinity chromatography technology)	Cader et al. (2016)	pubmed:27478939|imex:IM-26127	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12508068|imex:IM-26127-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000325686(transcript)|ensembl:ENST00000441843(transcript)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0004000"(adenosine deaminase activity)|go:"GO:0004731"(purine-nucleoside phosphorylase activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006954"(inflammatory response)|go:"GO:0017061"(S-methyl-5-thioadenosine phosphorylase activity)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0045087"(innate immune response)|go:"GO:0047975"(guanosine phosphorylase activity)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:1900542"(regulation of purine nucleotide metabolic process)|interpro:IPR003730(Protein of unknown function DUF152)|interpro:IPR011324(Cytotoxic necrotizing factor-like, catalytic)|interpro:IPR038371|ensembl:ENSG00000179630(gene)|refseq:NP_001121775.1|refseq:NP_694950.2|refseq:XP_005266318.1|refseq:XP_006719829.1|refseq:XP_011533235.1|refseq:XP_011533236.1|refseq:XP_016875883.1	ensembl:ENSG00000137478(gene)|ensembl:ENST00000409314(transcript)|go:"GO:0008289"(lipid binding)|go:"GO:0042995"(cell projection)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR031160|interpro:IPR034934|interpro:IPR035460|interpro:IPR035556|interpro:IPR036028	-	-	-	figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2016/08/08	2018/04/06	rogid:Y/gCMNfRuvW/8zUT3Fvq2ZR9I8o9606	rogid:0qiMRGKQIVPV3ByzuZom5nu6AZc9606	rigid:hVqlvzNvaAlh9ruzUf3c55i38xo	false	strep ii tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IV20	uniprotkb:B4DKR1	intact:EBI-12508070|ensembl:ENSP00000391747|ensembl:ENSP00000317619|uniprotkb:A2A3Z6|uniprotkb:Q8N8X5	intact:EBI-12508134	psi-mi:lacc1_human(display_long)|uniprotkb:LACC1(gene name)|psi-mi:LACC1(display_short)|uniprotkb:C13orf31(gene name synonym)|uniprotkb:FAMIN(gene name synonym)|uniprotkb:Fatty acid metabolism-immunity nexus(gene name synonym)|uniprotkb:Adenosine deaminase LACC1(gene name synonym)|uniprotkb:Guanosine phosphorylase LACC1(gene name synonym)|uniprotkb:Laccase domain-containing protein 1(gene name synonym)|uniprotkb:S-methyl-5'-thioadenosine phosphorylase LACC1(gene name synonym)	psi-mi:b4dkr1_human(display_long)|uniprotkb:Mitofilin(gene name synonym)	psi-mi:"MI:0004"(affinity chromatography technology)	Cader et al. (2016)	pubmed:27478939|imex:IM-26127	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12508068|imex:IM-26127-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000325686(transcript)|ensembl:ENST00000441843(transcript)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0004000"(adenosine deaminase activity)|go:"GO:0004731"(purine-nucleoside phosphorylase activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006954"(inflammatory response)|go:"GO:0017061"(S-methyl-5-thioadenosine phosphorylase activity)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0045087"(innate immune response)|go:"GO:0047975"(guanosine phosphorylase activity)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:1900542"(regulation of purine nucleotide metabolic process)|interpro:IPR003730(Protein of unknown function DUF152)|interpro:IPR011324(Cytotoxic necrotizing factor-like, catalytic)|interpro:IPR038371|ensembl:ENSG00000179630(gene)|refseq:NP_001121775.1|refseq:NP_694950.2|refseq:XP_005266318.1|refseq:XP_006719829.1|refseq:XP_011533235.1|refseq:XP_011533236.1|refseq:XP_016875883.1	go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR019133	-	-	-	figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2016/08/08	2018/04/06	rogid:Y/gCMNfRuvW/8zUT3Fvq2ZR9I8o9606	rogid:k39S9zl1WF98Pic3vlB1tCbrICM9606	rigid:hVqlvzNvaAlh9ruzUf3c55i38xo	false	strep ii tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IV20	uniprotkb:Q5EFE5	intact:EBI-12508070|ensembl:ENSP00000391747|ensembl:ENSP00000317619|uniprotkb:A2A3Z6|uniprotkb:Q8N8X5	intact:EBI-12508125	psi-mi:lacc1_human(display_long)|uniprotkb:LACC1(gene name)|psi-mi:LACC1(display_short)|uniprotkb:C13orf31(gene name synonym)|uniprotkb:FAMIN(gene name synonym)|uniprotkb:Fatty acid metabolism-immunity nexus(gene name synonym)|uniprotkb:Adenosine deaminase LACC1(gene name synonym)|uniprotkb:Guanosine phosphorylase LACC1(gene name synonym)|uniprotkb:Laccase domain-containing protein 1(gene name synonym)|uniprotkb:S-methyl-5'-thioadenosine phosphorylase LACC1(gene name synonym)	psi-mi:q5efe5_human(display_long)	psi-mi:"MI:0004"(affinity chromatography technology)	Cader et al. (2016)	pubmed:27478939|imex:IM-26127	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12508068|imex:IM-26127-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000325686(transcript)|ensembl:ENST00000441843(transcript)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0004000"(adenosine deaminase activity)|go:"GO:0004731"(purine-nucleoside phosphorylase activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006954"(inflammatory response)|go:"GO:0017061"(S-methyl-5-thioadenosine phosphorylase activity)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0045087"(innate immune response)|go:"GO:0047975"(guanosine phosphorylase activity)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:1900542"(regulation of purine nucleotide metabolic process)|interpro:IPR003730(Protein of unknown function DUF152)|interpro:IPR011324(Cytotoxic necrotizing factor-like, catalytic)|interpro:IPR038371|ensembl:ENSG00000179630(gene)|refseq:NP_001121775.1|refseq:NP_694950.2|refseq:XP_005266318.1|refseq:XP_006719829.1|refseq:XP_011533235.1|refseq:XP_011533236.1|refseq:XP_016875883.1	go:"GO:0016020"(membrane)|rcsb pdb:7CZP|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR036179	-	-	-	figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2016/08/08	2018/04/06	rogid:Y/gCMNfRuvW/8zUT3Fvq2ZR9I8o9606	rogid:do2rZI+TznxTvTzRnyn53K2DabI9606	rigid:hVqlvzNvaAlh9ruzUf3c55i38xo	false	strep ii tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IV20	uniprotkb:P49327	intact:EBI-12508070|ensembl:ENSP00000391747|ensembl:ENSP00000317619|uniprotkb:A2A3Z6|uniprotkb:Q8N8X5	intact:EBI-356658|uniprotkb:Q4LE83|uniprotkb:Q13479|uniprotkb:Q16702|uniprotkb:Q6P4U5|uniprotkb:Q6SS02|uniprotkb:Q969R1|uniprotkb:Q96C68|uniprotkb:Q96IT0|ensembl:ENSP00000304592	psi-mi:lacc1_human(display_long)|uniprotkb:LACC1(gene name)|psi-mi:LACC1(display_short)|uniprotkb:C13orf31(gene name synonym)|uniprotkb:FAMIN(gene name synonym)|uniprotkb:Fatty acid metabolism-immunity nexus(gene name synonym)|uniprotkb:Adenosine deaminase LACC1(gene name synonym)|uniprotkb:Guanosine phosphorylase LACC1(gene name synonym)|uniprotkb:Laccase domain-containing protein 1(gene name synonym)|uniprotkb:S-methyl-5'-thioadenosine phosphorylase LACC1(gene name synonym)	psi-mi:fas_human(display_long)|uniprotkb:FASN(gene name)|psi-mi:FASN(display_short)|uniprotkb:FAS(gene name synonym)|uniprotkb:Type I fatty acid synthase(gene name synonym)	psi-mi:"MI:0004"(affinity chromatography technology)	Cader et al. (2016)	pubmed:27478939|imex:IM-26127	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12508068|imex:IM-26127-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000325686(transcript)|ensembl:ENST00000441843(transcript)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0004000"(adenosine deaminase activity)|go:"GO:0004731"(purine-nucleoside phosphorylase activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006954"(inflammatory response)|go:"GO:0017061"(S-methyl-5-thioadenosine phosphorylase activity)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0045087"(innate immune response)|go:"GO:0047975"(guanosine phosphorylase activity)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:1900542"(regulation of purine nucleotide metabolic process)|interpro:IPR003730(Protein of unknown function DUF152)|interpro:IPR011324(Cytotoxic necrotizing factor-like, catalytic)|interpro:IPR038371|ensembl:ENSG00000179630(gene)|refseq:NP_001121775.1|refseq:NP_694950.2|refseq:XP_005266318.1|refseq:XP_006719829.1|refseq:XP_011533235.1|refseq:XP_011533236.1|refseq:XP_016875883.1	refseq:NP_004095.4|ensembl:ENSG00000169710(gene)|ensembl:ENST00000306749(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0002068"(glandular epithelial cell development)|go:"GO:0003723"(RNA binding)|go:"GO:0004313"([acyl-carrier-protein] S-acetyltransferase activity)|go:"GO:0004314"([acyl-carrier-protein] S-malonyltransferase activity)|go:"GO:0004315"(3-oxoacyl-[acyl-carrier-protein] synthase activity)|go:"GO:0004316"("3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity")|go:"GO:0004317"(3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity)|go:"GO:0004320"(oleoyl-[acyl-carrier-protein] hydrolase activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006084"(acetyl-CoA metabolic process)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0008611"(ether lipid biosynthetic process)|go:"GO:0008659"("(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity")|go:"GO:0008693"(3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity)|go:"GO:0016020"(membrane)|go:"GO:0016295"(myristoyl-[acyl-carrier-protein] hydrolase activity)|go:"GO:0016296"(palmitoyl-[acyl-carrier-protein] hydrolase activity)|go:"GO:0030223"(neutrophil differentiation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0030879"(mammary gland development)|go:"GO:0031177"(phosphopantetheine binding)|go:"GO:0042470"(melanosome)|go:"GO:0042587"(glycogen granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0047451"(3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0090557"(establishment of endothelial intestinal barrier)|go:"GO:0102131"(obsolete 3-oxo-glutaryl-[acp] methyl ester reductase activity)|go:"GO:0102132"(obsolete 3-oxo-pimeloyl-[acp] methyl ester reductase activity)|interpro:IPR001031(Thioesterase)|interpro:IPR001227(Acyl transferase region)|interpro:IPR006162(Phosphopantetheine attachment site)|interpro:IPR009081(Acyl carrier protein-like)|interpro:IPR011032(GroES-like)|interpro:IPR013149(Alcohol dehydrogenase, zinc-binding)|interpro:IPR013217(Methyltransferase type 12)|interpro:IPR013968(Polyketide synthase, KR)|interpro:IPR014030(Beta-ketoacyl synthase, N-terminal)|interpro:IPR014031(Beta-ketoacyl synthase, C-terminal)|interpro:IPR014043(Acyl transferase)|interpro:IPR016035(Acyl transferase/acyl hydrolase/lysophospholipase)|interpro:IPR016036(Malonyl-CoA ACP transacylase, ACP-binding)|interpro:IPR016039(Thiolase-like)|interpro:IPR018201|interpro:IPR020806|interpro:IPR020807|interpro:IPR020841|interpro:IPR020843|interpro:IPR029058|interpro:IPR029063|interpro:IPR032821|interpro:IPR036291|interpro:IPR036736|interpro:IPR042104|mint:P49327|rcsb pdb:1XKT|rcsb pdb:2CG5|rcsb pdb:2JFD|rcsb pdb:2JFK|rcsb pdb:2PX6|rcsb pdb:3HHD|rcsb pdb:3TJM|rcsb pdb:4PIV|rcsb pdb:4W82|rcsb pdb:4W9N|rcsb pdb:4Z49|rcsb pdb:5C37|rcsb pdb:6NNA|reactome:R-HSA-163765|reactome:R-HSA-199220|reactome:R-HSA-2426168|reactome:R-HSA-75105|reactome:R-HSA-9029558|go:"GO:0047117"("enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) activity")|refseq:XP_011521840.1|dip:DIP-33681N	-	-	-	figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2016/08/08	2018/04/06	rogid:Y/gCMNfRuvW/8zUT3Fvq2ZR9I8o9606	rogid:bQYEH/uQ6l+SPzLBDNCV5yP+yzs9606	rigid:hVqlvzNvaAlh9ruzUf3c55i38xo	false	strep ii tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IV20	uniprotkb:Q8TCU4	intact:EBI-12508070|ensembl:ENSP00000391747|ensembl:ENSP00000317619|uniprotkb:A2A3Z6|uniprotkb:Q8N8X5	intact:EBI-308651|uniprotkb:Q53S05|uniprotkb:Q580Q8|uniprotkb:Q86VP9|uniprotkb:Q9Y4G4|ensembl:ENSP00000482968|uniprotkb:A0A087WZY3	psi-mi:lacc1_human(display_long)|uniprotkb:LACC1(gene name)|psi-mi:LACC1(display_short)|uniprotkb:C13orf31(gene name synonym)|uniprotkb:FAMIN(gene name synonym)|uniprotkb:Fatty acid metabolism-immunity nexus(gene name synonym)|uniprotkb:Adenosine deaminase LACC1(gene name synonym)|uniprotkb:Guanosine phosphorylase LACC1(gene name synonym)|uniprotkb:Laccase domain-containing protein 1(gene name synonym)|uniprotkb:S-methyl-5'-thioadenosine phosphorylase LACC1(gene name synonym)	psi-mi:alms1_human(display_long)|uniprotkb:ALMS1(gene name)|psi-mi:ALMS1(display_short)|uniprotkb:KIAA0328(gene name synonym)	psi-mi:"MI:0004"(affinity chromatography technology)	Cader et al. (2016)	pubmed:27478939|imex:IM-26127	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12508351|imex:IM-26127-21	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000325686(transcript)|ensembl:ENST00000441843(transcript)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0004000"(adenosine deaminase activity)|go:"GO:0004731"(purine-nucleoside phosphorylase activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006954"(inflammatory response)|go:"GO:0017061"(S-methyl-5-thioadenosine phosphorylase activity)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0045087"(innate immune response)|go:"GO:0047975"(guanosine phosphorylase activity)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:1900542"(regulation of purine nucleotide metabolic process)|interpro:IPR003730(Protein of unknown function DUF152)|interpro:IPR011324(Cytotoxic necrotizing factor-like, catalytic)|interpro:IPR038371|ensembl:ENSG00000179630(gene)|refseq:NP_001121775.1|refseq:NP_694950.2|refseq:XP_005266318.1|refseq:XP_006719829.1|refseq:XP_011533235.1|refseq:XP_011533236.1|refseq:XP_016875883.1	ensembl:ENSG00000116127(gene)|ensembl:ENST00000613296(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0008017"(microtubule binding)|go:"GO:0016197"(endosomal transport)|go:"GO:0046599"(regulation of centriole replication)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR028781|interpro:IPR029299|interpro:IPR040972|mint:Q8TCU4|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_055935.4	-	-	-	figure legend:Supplementary Table 1-2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2016/08/08	2018/04/06	rogid:Y/gCMNfRuvW/8zUT3Fvq2ZR9I8o9606	rogid:e91Hcs947kpQHPVhWAJRtYegdPg9606	rigid:0bkSr8P9cUiTRnAuQJAayRI1BM0	false	strep ii tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IV20	uniprotkb:O14929	intact:EBI-12508070|ensembl:ENSP00000391747|ensembl:ENSP00000317619|uniprotkb:A2A3Z6|uniprotkb:Q8N8X5	intact:EBI-2339359|uniprotkb:Q53SU4|uniprotkb:Q53QF0|uniprotkb:Q49A44|uniprotkb:Q6P594|uniprotkb:Q8WWB9|ensembl:ENSP00000264108	psi-mi:lacc1_human(display_long)|uniprotkb:LACC1(gene name)|psi-mi:LACC1(display_short)|uniprotkb:C13orf31(gene name synonym)|uniprotkb:FAMIN(gene name synonym)|uniprotkb:Fatty acid metabolism-immunity nexus(gene name synonym)|uniprotkb:Adenosine deaminase LACC1(gene name synonym)|uniprotkb:Guanosine phosphorylase LACC1(gene name synonym)|uniprotkb:Laccase domain-containing protein 1(gene name synonym)|uniprotkb:S-methyl-5'-thioadenosine phosphorylase LACC1(gene name synonym)	psi-mi:hat1_human(display_long)|uniprotkb:HAT1(gene name)|psi-mi:HAT1(display_short)|uniprotkb:KAT1(gene name synonym)|uniprotkb:Histone acetyltransferase 1(gene name synonym)	psi-mi:"MI:0004"(affinity chromatography technology)	Cader et al. (2016)	pubmed:27478939|imex:IM-26127	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12508351|imex:IM-26127-21	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000325686(transcript)|ensembl:ENST00000441843(transcript)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0004000"(adenosine deaminase activity)|go:"GO:0004731"(purine-nucleoside phosphorylase activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006954"(inflammatory response)|go:"GO:0017061"(S-methyl-5-thioadenosine phosphorylase activity)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0045087"(innate immune response)|go:"GO:0047975"(guanosine phosphorylase activity)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:1900542"(regulation of purine nucleotide metabolic process)|interpro:IPR003730(Protein of unknown function DUF152)|interpro:IPR011324(Cytotoxic necrotizing factor-like, catalytic)|interpro:IPR038371|ensembl:ENSG00000179630(gene)|refseq:NP_001121775.1|refseq:NP_694950.2|refseq:XP_005266318.1|refseq:XP_006719829.1|refseq:XP_011533235.1|refseq:XP_011533236.1|refseq:XP_016875883.1	refseq:NP_003633.1|dip:DIP-52811N|ensembl:ENSG00000128708(gene)|ensembl:ENST00000264108(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006323"(DNA packaging)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006348"|go:"GO:0006475"(internal protein amino acid acetylation)|go:"GO:0007584"(response to nutrient)|go:"GO:0010485"(H4 histone acetyltransferase activity)|go:"GO:0016363"(nuclear matrix)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043967"(histone H4 acetylation)|interpro:IPR013523(Histone acetyltransferase HAT1, C-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR017380(Histone acetyltransferase type B, catalytic subunit)|interpro:IPR019467|interpro:IPR037113|mint:O14929|rcsb pdb:2P0W|rcsb pdb:6VO5|reactome:R-HSA-3214847	-	-	-	figure legend:Supplementary Table 1-2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2016/08/08	2018/04/06	rogid:Y/gCMNfRuvW/8zUT3Fvq2ZR9I8o9606	rogid:80KgRaid3NeRfAUdTHMQ/r0VuGo9606	rigid:0bkSr8P9cUiTRnAuQJAayRI1BM0	false	strep ii tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IV20	uniprotkb:B4DDF7	intact:EBI-12508070|ensembl:ENSP00000391747|ensembl:ENSP00000317619|uniprotkb:A2A3Z6|uniprotkb:Q8N8X5	intact:EBI-9977759	psi-mi:lacc1_human(display_long)|uniprotkb:LACC1(gene name)|psi-mi:LACC1(display_short)|uniprotkb:C13orf31(gene name synonym)|uniprotkb:FAMIN(gene name synonym)|uniprotkb:Fatty acid metabolism-immunity nexus(gene name synonym)|uniprotkb:Adenosine deaminase LACC1(gene name synonym)|uniprotkb:Guanosine phosphorylase LACC1(gene name synonym)|uniprotkb:Laccase domain-containing protein 1(gene name synonym)|uniprotkb:S-methyl-5'-thioadenosine phosphorylase LACC1(gene name synonym)	psi-mi:b4ddf7_human(display_long)	psi-mi:"MI:0004"(affinity chromatography technology)	Cader et al. (2016)	pubmed:27478939|imex:IM-26127	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12508351|imex:IM-26127-21	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000325686(transcript)|ensembl:ENST00000441843(transcript)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0004000"(adenosine deaminase activity)|go:"GO:0004731"(purine-nucleoside phosphorylase activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006954"(inflammatory response)|go:"GO:0017061"(S-methyl-5-thioadenosine phosphorylase activity)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0045087"(innate immune response)|go:"GO:0047975"(guanosine phosphorylase activity)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:1900542"(regulation of purine nucleotide metabolic process)|interpro:IPR003730(Protein of unknown function DUF152)|interpro:IPR011324(Cytotoxic necrotizing factor-like, catalytic)|interpro:IPR038371|ensembl:ENSG00000179630(gene)|refseq:NP_001121775.1|refseq:NP_694950.2|refseq:XP_005266318.1|refseq:XP_006719829.1|refseq:XP_011533235.1|refseq:XP_011533236.1|refseq:XP_016875883.1	interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR000357(HEAT)|interpro:IPR021133|interpro:IPR031090|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0065003"(protein-containing complex assembly)	-	-	-	figure legend:Supplementary Table 1-2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2016/08/08	2018/04/06	rogid:Y/gCMNfRuvW/8zUT3Fvq2ZR9I8o9606	rogid:ygjoHuYmXHoK0QoLKxuSWxX9XUQ9606	rigid:0bkSr8P9cUiTRnAuQJAayRI1BM0	false	strep ii tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IV20	uniprotkb:P43487	intact:EBI-12508070|ensembl:ENSP00000391747|ensembl:ENSP00000317619|uniprotkb:A2A3Z6|uniprotkb:Q8N8X5	intact:EBI-1032909|uniprotkb:Q53EY3|ensembl:ENSP00000327583	psi-mi:lacc1_human(display_long)|uniprotkb:LACC1(gene name)|psi-mi:LACC1(display_short)|uniprotkb:C13orf31(gene name synonym)|uniprotkb:FAMIN(gene name synonym)|uniprotkb:Fatty acid metabolism-immunity nexus(gene name synonym)|uniprotkb:Adenosine deaminase LACC1(gene name synonym)|uniprotkb:Guanosine phosphorylase LACC1(gene name synonym)|uniprotkb:Laccase domain-containing protein 1(gene name synonym)|uniprotkb:S-methyl-5'-thioadenosine phosphorylase LACC1(gene name synonym)	psi-mi:rang_human(display_long)|uniprotkb:RANBP1(gene name)|psi-mi:RANBP1(display_short)|uniprotkb:Ran-binding protein 1(gene name synonym)	psi-mi:"MI:0004"(affinity chromatography technology)	Cader et al. (2016)	pubmed:27478939|imex:IM-26127	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12508351|imex:IM-26127-21	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000325686(transcript)|ensembl:ENST00000441843(transcript)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0004000"(adenosine deaminase activity)|go:"GO:0004731"(purine-nucleoside phosphorylase activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006954"(inflammatory response)|go:"GO:0017061"(S-methyl-5-thioadenosine phosphorylase activity)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0045087"(innate immune response)|go:"GO:0047975"(guanosine phosphorylase activity)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:1900542"(regulation of purine nucleotide metabolic process)|interpro:IPR003730(Protein of unknown function DUF152)|interpro:IPR011324(Cytotoxic necrotizing factor-like, catalytic)|interpro:IPR038371|ensembl:ENSG00000179630(gene)|refseq:NP_001121775.1|refseq:NP_694950.2|refseq:XP_005266318.1|refseq:XP_006719829.1|refseq:XP_011533235.1|refseq:XP_011533236.1|refseq:XP_016875883.1	refseq:NP_002873.1|ensembl:ENSG00000099901(gene)|ensembl:ENST00000331821(transcript)|go:"GO:0005092"(GDP-dissociation inhibitor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0031267"(small GTPase binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046604"(positive regulation of mitotic centrosome separation)|go:"GO:0046907"(intracellular transport)|interpro:IPR000156(Ran Binding Protein 1)|interpro:IPR011993(Pleckstrin homology-type)|rcsb pdb:1K5D|rcsb pdb:1K5G|reactome:R-HSA-165054|refseq:NP_001265568.1|refseq:NP_001265569.1|dip:DIP-35058N	-	-	-	figure legend:Supplementary Table 1-2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2016/08/08	2018/04/06	rogid:Y/gCMNfRuvW/8zUT3Fvq2ZR9I8o9606	rogid:OWndphaUCDSO3+MGhJqcuQo2Lk09606	rigid:0bkSr8P9cUiTRnAuQJAayRI1BM0	false	strep ii tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IV20	uniprotkb:A4D1U5	intact:EBI-12508070|ensembl:ENSP00000391747|ensembl:ENSP00000317619|uniprotkb:A2A3Z6|uniprotkb:Q8N8X5	intact:EBI-12508181	psi-mi:lacc1_human(display_long)|uniprotkb:LACC1(gene name)|psi-mi:LACC1(display_short)|uniprotkb:C13orf31(gene name synonym)|uniprotkb:FAMIN(gene name synonym)|uniprotkb:Fatty acid metabolism-immunity nexus(gene name synonym)|uniprotkb:Adenosine deaminase LACC1(gene name synonym)|uniprotkb:Guanosine phosphorylase LACC1(gene name synonym)|uniprotkb:Laccase domain-containing protein 1(gene name synonym)|uniprotkb:S-methyl-5'-thioadenosine phosphorylase LACC1(gene name synonym)	psi-mi:a4d1u5_human(display_long)|uniprotkb:FLJ10842(gene name)|psi-mi:FLJ10842(display_short)|uniprotkb:MULK(gene name synonym)|uniprotkb:hCG_39451(orf name)|uniprotkb:tcag7.330(orf name)	psi-mi:"MI:0004"(affinity chromatography technology)	Cader et al. (2016)	pubmed:27478939|imex:IM-26127	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12508351|imex:IM-26127-21	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000325686(transcript)|ensembl:ENST00000441843(transcript)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0004000"(adenosine deaminase activity)|go:"GO:0004731"(purine-nucleoside phosphorylase activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006954"(inflammatory response)|go:"GO:0017061"(S-methyl-5-thioadenosine phosphorylase activity)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0045087"(innate immune response)|go:"GO:0047975"(guanosine phosphorylase activity)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:1900542"(regulation of purine nucleotide metabolic process)|interpro:IPR003730(Protein of unknown function DUF152)|interpro:IPR011324(Cytotoxic necrotizing factor-like, catalytic)|interpro:IPR038371|ensembl:ENSG00000179630(gene)|refseq:NP_001121775.1|refseq:NP_694950.2|refseq:XP_005266318.1|refseq:XP_006719829.1|refseq:XP_011533235.1|refseq:XP_011533236.1|refseq:XP_016875883.1	go:"GO:0001729"(ceramide kinase activity)|go:"GO:0003951"(NAD+ kinase activity)|go:"GO:0004143"(diacylglycerol kinase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0016020"(membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0047620"(acylglycerol kinase activity)|refseq:NP_060708.1|refseq:XP_011514699.1|interpro:IPR001206(Diacylglycerol kinase, catalytic region)|interpro:IPR016064(ATP-NAD kinase, PpnK-type)|interpro:IPR017438(ATP-NAD kinase, PpnK-type, alpha/beta)	-	-	-	figure legend:Supplementary Table 1-2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2016/08/08	2018/04/06	rogid:Y/gCMNfRuvW/8zUT3Fvq2ZR9I8o9606	rogid:aUz/aYnkviiUE/ijNEddfOQmjZQ9606	rigid:0bkSr8P9cUiTRnAuQJAayRI1BM0	false	strep ii tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IV20	uniprotkb:K7EIG1	intact:EBI-12508070|ensembl:ENSP00000391747|ensembl:ENSP00000317619|uniprotkb:A2A3Z6|uniprotkb:Q8N8X5	intact:EBI-12508166|ensembl:ENSP00000464732	psi-mi:lacc1_human(display_long)|uniprotkb:LACC1(gene name)|psi-mi:LACC1(display_short)|uniprotkb:C13orf31(gene name synonym)|uniprotkb:FAMIN(gene name synonym)|uniprotkb:Fatty acid metabolism-immunity nexus(gene name synonym)|uniprotkb:Adenosine deaminase LACC1(gene name synonym)|uniprotkb:Guanosine phosphorylase LACC1(gene name synonym)|uniprotkb:Laccase domain-containing protein 1(gene name synonym)|uniprotkb:S-methyl-5'-thioadenosine phosphorylase LACC1(gene name synonym)	psi-mi:k7eig1_human(display_long)|uniprotkb:CLUH(gene name)|psi-mi:CLUH(display_short)	psi-mi:"MI:0004"(affinity chromatography technology)	Cader et al. (2016)	pubmed:27478939|imex:IM-26127	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12508351|imex:IM-26127-21	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000325686(transcript)|ensembl:ENST00000441843(transcript)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0004000"(adenosine deaminase activity)|go:"GO:0004731"(purine-nucleoside phosphorylase activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006954"(inflammatory response)|go:"GO:0017061"(S-methyl-5-thioadenosine phosphorylase activity)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0045087"(innate immune response)|go:"GO:0047975"(guanosine phosphorylase activity)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:1900542"(regulation of purine nucleotide metabolic process)|interpro:IPR003730(Protein of unknown function DUF152)|interpro:IPR011324(Cytotoxic necrotizing factor-like, catalytic)|interpro:IPR038371|ensembl:ENSG00000179630(gene)|refseq:NP_001121775.1|refseq:NP_694950.2|refseq:XP_005266318.1|refseq:XP_006719829.1|refseq:XP_011533235.1|refseq:XP_011533236.1|refseq:XP_016875883.1	ensembl:ENSG00000132361(gene)|ensembl:ENST00000575014(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0048312"(intracellular distribution of mitochondria)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR023231|interpro:IPR025697|interpro:IPR027523|interpro:IPR028275|interpro:IPR033646	-	-	-	figure legend:Supplementary Table 1-2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2016/08/08	2018/04/06	rogid:Y/gCMNfRuvW/8zUT3Fvq2ZR9I8o9606	rogid:944DSX7wGR6xTSvKXicRBKVeDrs9606	rigid:0bkSr8P9cUiTRnAuQJAayRI1BM0	false	strep ii tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IV20	uniprotkb:B7Z3V1	intact:EBI-12508070|ensembl:ENSP00000391747|ensembl:ENSP00000317619|uniprotkb:A2A3Z6|uniprotkb:Q8N8X5	intact:EBI-12508149	psi-mi:lacc1_human(display_long)|uniprotkb:LACC1(gene name)|psi-mi:LACC1(display_short)|uniprotkb:C13orf31(gene name synonym)|uniprotkb:FAMIN(gene name synonym)|uniprotkb:Fatty acid metabolism-immunity nexus(gene name synonym)|uniprotkb:Adenosine deaminase LACC1(gene name synonym)|uniprotkb:Guanosine phosphorylase LACC1(gene name synonym)|uniprotkb:Laccase domain-containing protein 1(gene name synonym)|uniprotkb:S-methyl-5'-thioadenosine phosphorylase LACC1(gene name synonym)	psi-mi:b7z3v1_human(display_long)	psi-mi:"MI:0004"(affinity chromatography technology)	Cader et al. (2016)	pubmed:27478939|imex:IM-26127	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12508351|imex:IM-26127-21	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000325686(transcript)|ensembl:ENST00000441843(transcript)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0004000"(adenosine deaminase activity)|go:"GO:0004731"(purine-nucleoside phosphorylase activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006954"(inflammatory response)|go:"GO:0017061"(S-methyl-5-thioadenosine phosphorylase activity)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0045087"(innate immune response)|go:"GO:0047975"(guanosine phosphorylase activity)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:1900542"(regulation of purine nucleotide metabolic process)|interpro:IPR003730(Protein of unknown function DUF152)|interpro:IPR011324(Cytotoxic necrotizing factor-like, catalytic)|interpro:IPR038371|ensembl:ENSG00000179630(gene)|refseq:NP_001121775.1|refseq:NP_694950.2|refseq:XP_005266318.1|refseq:XP_006719829.1|refseq:XP_011533235.1|refseq:XP_011533236.1|refseq:XP_016875883.1	go:"GO:0005524"(ATP binding)|go:"GO:0008556"(P-type potassium transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR023299|interpro:IPR018303|interpro:IPR023298|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR005775(ATPase, P-type cation exchange, alpha subunit, eukaryotic)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR023214|interpro:IPR044492|interpro:IPR036412	-	-	-	figure legend:Supplementary Table 1-2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2016/08/08	2018/04/06	rogid:Y/gCMNfRuvW/8zUT3Fvq2ZR9I8o9606	rogid:pr2tcG3ByFJzAjutV9gQghP7dp49606	rigid:0bkSr8P9cUiTRnAuQJAayRI1BM0	false	strep ii tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IV20	uniprotkb:Q16531	intact:EBI-12508070|ensembl:ENSP00000391747|ensembl:ENSP00000317619|uniprotkb:A2A3Z6|uniprotkb:Q8N8X5	intact:EBI-350322|uniprotkb:A6NG77|uniprotkb:O15176|uniprotkb:Q13289|ensembl:ENSP00000301764|ensembl:ENSP00000506223|ensembl:ENSP00000506685|uniprotkb:Q58F96|uniprotkb:B2R648|uniprotkb:B4DG00	psi-mi:lacc1_human(display_long)|uniprotkb:LACC1(gene name)|psi-mi:LACC1(display_short)|uniprotkb:C13orf31(gene name synonym)|uniprotkb:FAMIN(gene name synonym)|uniprotkb:Fatty acid metabolism-immunity nexus(gene name synonym)|uniprotkb:Adenosine deaminase LACC1(gene name synonym)|uniprotkb:Guanosine phosphorylase LACC1(gene name synonym)|uniprotkb:Laccase domain-containing protein 1(gene name synonym)|uniprotkb:S-methyl-5'-thioadenosine phosphorylase LACC1(gene name synonym)	psi-mi:ddb1_human(display_long)|uniprotkb:DDB1(gene name)|psi-mi:DDB1(display_short)|uniprotkb:Damage-specific DNA-binding protein 1(gene name synonym)|uniprotkb:UV-damaged DNA-binding factor(gene name synonym)|uniprotkb:DDB p127 subunit(gene name synonym)|uniprotkb:DNA damage-binding protein a(gene name synonym)|uniprotkb:UV-damaged DNA-binding protein 1(gene name synonym)|uniprotkb:Xeroderma pigmentosum group E-complementing protein(gene name synonym)|uniprotkb:XPE-binding factor(gene name synonym)|uniprotkb:HBV X-associated protein 1(gene name synonym)|uniprotkb:XAP1(gene name synonym)	psi-mi:"MI:0004"(affinity chromatography technology)	Cader et al. (2016)	pubmed:27478939|imex:IM-26127	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12508351|imex:IM-26127-21	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000325686(transcript)|ensembl:ENST00000441843(transcript)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0004000"(adenosine deaminase activity)|go:"GO:0004731"(purine-nucleoside phosphorylase activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006954"(inflammatory response)|go:"GO:0017061"(S-methyl-5-thioadenosine phosphorylase activity)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0045087"(innate immune response)|go:"GO:0047975"(guanosine phosphorylase activity)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:1900542"(regulation of purine nucleotide metabolic process)|interpro:IPR003730(Protein of unknown function DUF152)|interpro:IPR011324(Cytotoxic necrotizing factor-like, catalytic)|interpro:IPR038371|ensembl:ENSG00000179630(gene)|refseq:NP_001121775.1|refseq:NP_694950.2|refseq:XP_005266318.1|refseq:XP_006719829.1|refseq:XP_011533235.1|refseq:XP_011533236.1|refseq:XP_016875883.1	refseq:NP_001914.3|rcsb pdb:3I89|rcsb pdb:3I8C|rcsb pdb:3I8E|rcsb pdb:4A08|rcsb pdb:4A09|rcsb pdb:4A0A|rcsb pdb:4A0B|rcsb pdb:4A0K|rcsb pdb:4A0L|rcsb pdb:4A11|rcsb pdb:4CI1|rcsb pdb:4CI2|rcsb pdb:4CI3|rcsb pdb:4E54|rcsb pdb:4E5Z|rcsb pdb:4TZ4|rcsb pdb:5FQD|rcsb pdb:5HXB|rcsb pdb:5JK7|rcsb pdb:5V3O|rcsb pdb:6BN7|ensembl:ENSG00000167986(gene)|ensembl:ENST00000301764(transcript)|ensembl:ENST00000680367(transcript)|ensembl:ENST00000681803(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030674"(protein-macromolecule adaptor activity)|rcsb pdb:6BN8|rcsb pdb:6BN9|rcsb pdb:6BNB|rcsb pdb:6BOY|rcsb pdb:6DSZ|rcsb pdb:6FCV|rcsb pdb:6H0F|rcsb pdb:6H0G|rcsb pdb:6PAI|rcsb pdb:6Q0R|rcsb pdb:6Q0V|rcsb pdb:6Q0W|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|rcsb pdb:6R92|rcsb pdb:6SJ7|rcsb pdb:6TD3|rcsb pdb:6UD7|rcsb pdb:6UE5|rcsb pdb:6UML|rcsb pdb:6XK9|rcsb pdb:7LPS|reactome:R-HSA-110314|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-8951664|go:"GO:0031464"(Cul4A-RING E3 ubiquitin ligase complex)|go:"GO:0031465"(Cul4B-RING E3 ubiquitin ligase complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046726"(positive regulation by virus of viral protein levels in host cell)|go:"GO:0048511"(rhythmic process)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070914"(UV-damage excision repair)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1901990"(regulation of mitotic cell cycle phase transition)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|interpro:IPR004871(Cleavage and polyadenylation specificity factor, A subunit, C-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018846|interpro:IPR031297|interpro:IPR036322|mint:Q16531|rcsb pdb:2B5L|rcsb pdb:2B5M|rcsb pdb:2B5N|rcsb pdb:2HYE|rcsb pdb:3E0C|rcsb pdb:3EI1|rcsb pdb:3EI2|rcsb pdb:3EI3|rcsb pdb:3EI4|rcsb pdb:3I7H|rcsb pdb:3I7K|rcsb pdb:3I7L|rcsb pdb:3I7N|rcsb pdb:3I7O|rcsb pdb:3I7P|dip:DIP-430N	-	-	-	figure legend:Supplementary Table 1-2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2016/08/08	2018/04/06	rogid:Y/gCMNfRuvW/8zUT3Fvq2ZR9I8o9606	rogid:qgMjZqvlsbGIGn2qM/pnLTtGyGM9606	rigid:0bkSr8P9cUiTRnAuQJAayRI1BM0	false	strep ii tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IV20	uniprotkb:Q6FHQ0	intact:EBI-12508070|ensembl:ENSP00000391747|ensembl:ENSP00000317619|uniprotkb:A2A3Z6|uniprotkb:Q8N8X5	intact:EBI-1057040	psi-mi:lacc1_human(display_long)|uniprotkb:LACC1(gene name)|psi-mi:LACC1(display_short)|uniprotkb:C13orf31(gene name synonym)|uniprotkb:FAMIN(gene name synonym)|uniprotkb:Fatty acid metabolism-immunity nexus(gene name synonym)|uniprotkb:Adenosine deaminase LACC1(gene name synonym)|uniprotkb:Guanosine phosphorylase LACC1(gene name synonym)|uniprotkb:Laccase domain-containing protein 1(gene name synonym)|uniprotkb:S-methyl-5'-thioadenosine phosphorylase LACC1(gene name synonym)	psi-mi:q6fhq0_human(display_long)|uniprotkb:RBBP7(gene name)|psi-mi:RBBP7(display_short)|uniprotkb:hCG_20110(orf name)	psi-mi:"MI:0004"(affinity chromatography technology)	Cader et al. (2016)	pubmed:27478939|imex:IM-26127	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12508351|imex:IM-26127-21	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000325686(transcript)|ensembl:ENST00000441843(transcript)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0004000"(adenosine deaminase activity)|go:"GO:0004731"(purine-nucleoside phosphorylase activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006954"(inflammatory response)|go:"GO:0017061"(S-methyl-5-thioadenosine phosphorylase activity)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0045087"(innate immune response)|go:"GO:0047975"(guanosine phosphorylase activity)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:1900542"(regulation of purine nucleotide metabolic process)|interpro:IPR003730(Protein of unknown function DUF152)|interpro:IPR011324(Cytotoxic necrotizing factor-like, catalytic)|interpro:IPR038371|ensembl:ENSG00000179630(gene)|refseq:NP_001121775.1|refseq:NP_694950.2|refseq:XP_005266318.1|refseq:XP_006719829.1|refseq:XP_011533235.1|refseq:XP_011533236.1|refseq:XP_016875883.1	refseq:NP_002884.1|interpro:IPR020472|interpro:IPR022052|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR001680(WD40 repeat)|interpro:IPR019775|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0016581"(NuRD complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0048545"(response to steroid hormone)|interpro:IPR036322	-	-	-	figure legend:Supplementary Table 1-2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2016/08/08	2018/04/06	rogid:Y/gCMNfRuvW/8zUT3Fvq2ZR9I8o9606	rogid:qANLG0ui7jm3Uy4+IRnxR8Kir7c9606	rigid:0bkSr8P9cUiTRnAuQJAayRI1BM0	false	strep ii tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IV20	uniprotkb:Q96ST3	intact:EBI-12508070|ensembl:ENSP00000391747|ensembl:ENSP00000317619|uniprotkb:A2A3Z6|uniprotkb:Q8N8X5	intact:EBI-347218|uniprotkb:Q8N8N4|uniprotkb:Q8NC83|uniprotkb:Q8WV18|uniprotkb:Q96L98|uniprotkb:Q9UFQ1|intact:EBI-28985143|ensembl:ENSP00000353622|ensembl:ENSP00000378402|ensembl:ENSP00000378403|uniprotkb:B2RNS5	psi-mi:lacc1_human(display_long)|uniprotkb:LACC1(gene name)|psi-mi:LACC1(display_short)|uniprotkb:C13orf31(gene name synonym)|uniprotkb:FAMIN(gene name synonym)|uniprotkb:Fatty acid metabolism-immunity nexus(gene name synonym)|uniprotkb:Adenosine deaminase LACC1(gene name synonym)|uniprotkb:Guanosine phosphorylase LACC1(gene name synonym)|uniprotkb:Laccase domain-containing protein 1(gene name synonym)|uniprotkb:S-methyl-5'-thioadenosine phosphorylase LACC1(gene name synonym)	psi-mi:sin3a_human(display_long)|uniprotkb:SIN3A(gene name)|psi-mi:SIN3A(display_short)|uniprotkb:Transcriptional corepressor Sin3a(gene name synonym)|uniprotkb:Histone deacetylase complex subunit Sin3a(gene name synonym)	psi-mi:"MI:0004"(affinity chromatography technology)	Cader et al. (2016)	pubmed:27478939|imex:IM-26127	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12508351|imex:IM-26127-21	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000325686(transcript)|ensembl:ENST00000441843(transcript)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0004000"(adenosine deaminase activity)|go:"GO:0004731"(purine-nucleoside phosphorylase activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006954"(inflammatory response)|go:"GO:0017061"(S-methyl-5-thioadenosine phosphorylase activity)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0045087"(innate immune response)|go:"GO:0047975"(guanosine phosphorylase activity)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:1900542"(regulation of purine nucleotide metabolic process)|interpro:IPR003730(Protein of unknown function DUF152)|interpro:IPR011324(Cytotoxic necrotizing factor-like, catalytic)|interpro:IPR038371|ensembl:ENSG00000179630(gene)|refseq:NP_001121775.1|refseq:NP_694950.2|refseq:XP_005266318.1|refseq:XP_006719829.1|refseq:XP_011533235.1|refseq:XP_011533236.1|refseq:XP_016875883.1	refseq:XP_006720528.1|ensembl:ENSG00000169375(gene)|ensembl:ENST00000360439(transcript)|ensembl:ENST00000394947(transcript)|ensembl:ENST00000394949(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000776"(kinetochore)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006260"(DNA replication)|go:"GO:0006476"(protein deacetylation)|go:"GO:0007568"(aging)|go:"GO:0010817"(regulation of hormone levels)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0021895"(cerebral cortex neuron differentiation)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0031937"(obsolete positive regulation of chromatin silencing)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043619"(regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048511"(rhythmic process)|go:"GO:0051595"(response to methylglyoxal)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|go:"GO:1901675"(negative regulation of histone H3-K27 acetylation)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|interpro:IPR003822(Paired amphipathic helix)|interpro:IPR013194(Histone deacetylase interacting)|interpro:IPR031693|interpro:IPR036600|interpro:IPR037969|interpro:IPR039774|mint:Q96ST3|reactome:R-HSA-3899300|reactome:R-HSA-400206|reactome:R-HSA-427413|reactome:R-HSA-8936459|reactome:R-HSA-9022538|reactome:R-HSA-9022692|reactome:R-HSA-9022699|reactome:R-HSA-9022702|rcsb pdb:1PO4|reactome:R-HSA-9615017|reactome:R-HSA-9707564|reactome:R-HSA-983231|refseq:XP_006720529.1|refseq:XP_006720530.1|refseq:NP_001138829.1|refseq:NP_001138830.1|refseq:NP_056292.1|ensembl:ENSP00000353622|ensembl:ENSP00000378402|ensembl:ENSP00000378403|dip:DIP-31515N	-	-	-	figure legend:Supplementary Table 1-2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2016/08/08	2018/04/06	rogid:Y/gCMNfRuvW/8zUT3Fvq2ZR9I8o9606	rogid:pO/FziDcMNQRfy6ePi6eNKELXVM9606	rigid:0bkSr8P9cUiTRnAuQJAayRI1BM0	false	strep ii tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IV20	uniprotkb:E9PG19	intact:EBI-12508070|ensembl:ENSP00000391747|ensembl:ENSP00000317619|uniprotkb:A2A3Z6|uniprotkb:Q8N8X5	intact:EBI-12508139|ensembl:ENSP00000386987	psi-mi:lacc1_human(display_long)|uniprotkb:LACC1(gene name)|psi-mi:LACC1(display_short)|uniprotkb:C13orf31(gene name synonym)|uniprotkb:FAMIN(gene name synonym)|uniprotkb:Fatty acid metabolism-immunity nexus(gene name synonym)|uniprotkb:Adenosine deaminase LACC1(gene name synonym)|uniprotkb:Guanosine phosphorylase LACC1(gene name synonym)|uniprotkb:Laccase domain-containing protein 1(gene name synonym)|uniprotkb:S-methyl-5'-thioadenosine phosphorylase LACC1(gene name synonym)	psi-mi:e9pg19_human(display_long)|uniprotkb:FCHSD2(gene name)|psi-mi:FCHSD2(display_short)	psi-mi:"MI:0004"(affinity chromatography technology)	Cader et al. (2016)	pubmed:27478939|imex:IM-26127	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12508351|imex:IM-26127-21	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000325686(transcript)|ensembl:ENST00000441843(transcript)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0004000"(adenosine deaminase activity)|go:"GO:0004731"(purine-nucleoside phosphorylase activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006954"(inflammatory response)|go:"GO:0017061"(S-methyl-5-thioadenosine phosphorylase activity)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0045087"(innate immune response)|go:"GO:0047975"(guanosine phosphorylase activity)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:1900542"(regulation of purine nucleotide metabolic process)|interpro:IPR003730(Protein of unknown function DUF152)|interpro:IPR011324(Cytotoxic necrotizing factor-like, catalytic)|interpro:IPR038371|ensembl:ENSG00000179630(gene)|refseq:NP_001121775.1|refseq:NP_694950.2|refseq:XP_005266318.1|refseq:XP_006719829.1|refseq:XP_011533235.1|refseq:XP_011533236.1|refseq:XP_016875883.1	ensembl:ENSG00000137478(gene)|ensembl:ENST00000409314(transcript)|go:"GO:0008289"(lipid binding)|go:"GO:0042995"(cell projection)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR031160|interpro:IPR034934|interpro:IPR035460|interpro:IPR035556|interpro:IPR036028	-	-	-	figure legend:Supplementary Table 1-2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2016/08/08	2018/04/06	rogid:Y/gCMNfRuvW/8zUT3Fvq2ZR9I8o9606	rogid:0qiMRGKQIVPV3ByzuZom5nu6AZc9606	rigid:0bkSr8P9cUiTRnAuQJAayRI1BM0	false	strep ii tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IV20	uniprotkb:B4DKR1	intact:EBI-12508070|ensembl:ENSP00000391747|ensembl:ENSP00000317619|uniprotkb:A2A3Z6|uniprotkb:Q8N8X5	intact:EBI-12508134	psi-mi:lacc1_human(display_long)|uniprotkb:LACC1(gene name)|psi-mi:LACC1(display_short)|uniprotkb:C13orf31(gene name synonym)|uniprotkb:FAMIN(gene name synonym)|uniprotkb:Fatty acid metabolism-immunity nexus(gene name synonym)|uniprotkb:Adenosine deaminase LACC1(gene name synonym)|uniprotkb:Guanosine phosphorylase LACC1(gene name synonym)|uniprotkb:Laccase domain-containing protein 1(gene name synonym)|uniprotkb:S-methyl-5'-thioadenosine phosphorylase LACC1(gene name synonym)	psi-mi:b4dkr1_human(display_long)|uniprotkb:Mitofilin(gene name synonym)	psi-mi:"MI:0004"(affinity chromatography technology)	Cader et al. (2016)	pubmed:27478939|imex:IM-26127	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12508351|imex:IM-26127-21	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000325686(transcript)|ensembl:ENST00000441843(transcript)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0004000"(adenosine deaminase activity)|go:"GO:0004731"(purine-nucleoside phosphorylase activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006954"(inflammatory response)|go:"GO:0017061"(S-methyl-5-thioadenosine phosphorylase activity)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0045087"(innate immune response)|go:"GO:0047975"(guanosine phosphorylase activity)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:1900542"(regulation of purine nucleotide metabolic process)|interpro:IPR003730(Protein of unknown function DUF152)|interpro:IPR011324(Cytotoxic necrotizing factor-like, catalytic)|interpro:IPR038371|ensembl:ENSG00000179630(gene)|refseq:NP_001121775.1|refseq:NP_694950.2|refseq:XP_005266318.1|refseq:XP_006719829.1|refseq:XP_011533235.1|refseq:XP_011533236.1|refseq:XP_016875883.1	go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR019133	-	-	-	figure legend:Supplementary Table 1-2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2016/08/08	2018/04/06	rogid:Y/gCMNfRuvW/8zUT3Fvq2ZR9I8o9606	rogid:k39S9zl1WF98Pic3vlB1tCbrICM9606	rigid:0bkSr8P9cUiTRnAuQJAayRI1BM0	false	strep ii tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IV20	uniprotkb:Q5EFE5	intact:EBI-12508070|ensembl:ENSP00000391747|ensembl:ENSP00000317619|uniprotkb:A2A3Z6|uniprotkb:Q8N8X5	intact:EBI-12508125	psi-mi:lacc1_human(display_long)|uniprotkb:LACC1(gene name)|psi-mi:LACC1(display_short)|uniprotkb:C13orf31(gene name synonym)|uniprotkb:FAMIN(gene name synonym)|uniprotkb:Fatty acid metabolism-immunity nexus(gene name synonym)|uniprotkb:Adenosine deaminase LACC1(gene name synonym)|uniprotkb:Guanosine phosphorylase LACC1(gene name synonym)|uniprotkb:Laccase domain-containing protein 1(gene name synonym)|uniprotkb:S-methyl-5'-thioadenosine phosphorylase LACC1(gene name synonym)	psi-mi:q5efe5_human(display_long)	psi-mi:"MI:0004"(affinity chromatography technology)	Cader et al. (2016)	pubmed:27478939|imex:IM-26127	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12508351|imex:IM-26127-21	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000325686(transcript)|ensembl:ENST00000441843(transcript)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0004000"(adenosine deaminase activity)|go:"GO:0004731"(purine-nucleoside phosphorylase activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006954"(inflammatory response)|go:"GO:0017061"(S-methyl-5-thioadenosine phosphorylase activity)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0045087"(innate immune response)|go:"GO:0047975"(guanosine phosphorylase activity)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:1900542"(regulation of purine nucleotide metabolic process)|interpro:IPR003730(Protein of unknown function DUF152)|interpro:IPR011324(Cytotoxic necrotizing factor-like, catalytic)|interpro:IPR038371|ensembl:ENSG00000179630(gene)|refseq:NP_001121775.1|refseq:NP_694950.2|refseq:XP_005266318.1|refseq:XP_006719829.1|refseq:XP_011533235.1|refseq:XP_011533236.1|refseq:XP_016875883.1	go:"GO:0016020"(membrane)|rcsb pdb:7CZP|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR036179	-	-	-	figure legend:Supplementary Table 1-2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2016/08/08	2018/04/06	rogid:Y/gCMNfRuvW/8zUT3Fvq2ZR9I8o9606	rogid:do2rZI+TznxTvTzRnyn53K2DabI9606	rigid:0bkSr8P9cUiTRnAuQJAayRI1BM0	false	strep ii tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IV20	uniprotkb:P49327	intact:EBI-12508070|ensembl:ENSP00000391747|ensembl:ENSP00000317619|uniprotkb:A2A3Z6|uniprotkb:Q8N8X5	intact:EBI-356658|uniprotkb:Q4LE83|uniprotkb:Q13479|uniprotkb:Q16702|uniprotkb:Q6P4U5|uniprotkb:Q6SS02|uniprotkb:Q969R1|uniprotkb:Q96C68|uniprotkb:Q96IT0|ensembl:ENSP00000304592	psi-mi:lacc1_human(display_long)|uniprotkb:LACC1(gene name)|psi-mi:LACC1(display_short)|uniprotkb:C13orf31(gene name synonym)|uniprotkb:FAMIN(gene name synonym)|uniprotkb:Fatty acid metabolism-immunity nexus(gene name synonym)|uniprotkb:Adenosine deaminase LACC1(gene name synonym)|uniprotkb:Guanosine phosphorylase LACC1(gene name synonym)|uniprotkb:Laccase domain-containing protein 1(gene name synonym)|uniprotkb:S-methyl-5'-thioadenosine phosphorylase LACC1(gene name synonym)	psi-mi:fas_human(display_long)|uniprotkb:FASN(gene name)|psi-mi:FASN(display_short)|uniprotkb:FAS(gene name synonym)|uniprotkb:Type I fatty acid synthase(gene name synonym)	psi-mi:"MI:0004"(affinity chromatography technology)	Cader et al. (2016)	pubmed:27478939|imex:IM-26127	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12508351|imex:IM-26127-21	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000325686(transcript)|ensembl:ENST00000441843(transcript)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0004000"(adenosine deaminase activity)|go:"GO:0004731"(purine-nucleoside phosphorylase activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006954"(inflammatory response)|go:"GO:0017061"(S-methyl-5-thioadenosine phosphorylase activity)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0045087"(innate immune response)|go:"GO:0047975"(guanosine phosphorylase activity)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:1900542"(regulation of purine nucleotide metabolic process)|interpro:IPR003730(Protein of unknown function DUF152)|interpro:IPR011324(Cytotoxic necrotizing factor-like, catalytic)|interpro:IPR038371|ensembl:ENSG00000179630(gene)|refseq:NP_001121775.1|refseq:NP_694950.2|refseq:XP_005266318.1|refseq:XP_006719829.1|refseq:XP_011533235.1|refseq:XP_011533236.1|refseq:XP_016875883.1	refseq:NP_004095.4|ensembl:ENSG00000169710(gene)|ensembl:ENST00000306749(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0002068"(glandular epithelial cell development)|go:"GO:0003723"(RNA binding)|go:"GO:0004313"([acyl-carrier-protein] S-acetyltransferase activity)|go:"GO:0004314"([acyl-carrier-protein] S-malonyltransferase activity)|go:"GO:0004315"(3-oxoacyl-[acyl-carrier-protein] synthase activity)|go:"GO:0004316"("3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity")|go:"GO:0004317"(3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity)|go:"GO:0004320"(oleoyl-[acyl-carrier-protein] hydrolase activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006084"(acetyl-CoA metabolic process)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0008611"(ether lipid biosynthetic process)|go:"GO:0008659"("(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity")|go:"GO:0008693"(3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity)|go:"GO:0016020"(membrane)|go:"GO:0016295"(myristoyl-[acyl-carrier-protein] hydrolase activity)|go:"GO:0016296"(palmitoyl-[acyl-carrier-protein] hydrolase activity)|go:"GO:0030223"(neutrophil differentiation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0030879"(mammary gland development)|go:"GO:0031177"(phosphopantetheine binding)|go:"GO:0042470"(melanosome)|go:"GO:0042587"(glycogen granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0047451"(3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0090557"(establishment of endothelial intestinal barrier)|go:"GO:0102131"(obsolete 3-oxo-glutaryl-[acp] methyl ester reductase activity)|go:"GO:0102132"(obsolete 3-oxo-pimeloyl-[acp] methyl ester reductase activity)|interpro:IPR001031(Thioesterase)|interpro:IPR001227(Acyl transferase region)|interpro:IPR006162(Phosphopantetheine attachment site)|interpro:IPR009081(Acyl carrier protein-like)|interpro:IPR011032(GroES-like)|interpro:IPR013149(Alcohol dehydrogenase, zinc-binding)|interpro:IPR013217(Methyltransferase type 12)|interpro:IPR013968(Polyketide synthase, KR)|interpro:IPR014030(Beta-ketoacyl synthase, N-terminal)|interpro:IPR014031(Beta-ketoacyl synthase, C-terminal)|interpro:IPR014043(Acyl transferase)|interpro:IPR016035(Acyl transferase/acyl hydrolase/lysophospholipase)|interpro:IPR016036(Malonyl-CoA ACP transacylase, ACP-binding)|interpro:IPR016039(Thiolase-like)|interpro:IPR018201|interpro:IPR020806|interpro:IPR020807|interpro:IPR020841|interpro:IPR020843|interpro:IPR029058|interpro:IPR029063|interpro:IPR032821|interpro:IPR036291|interpro:IPR036736|interpro:IPR042104|mint:P49327|rcsb pdb:1XKT|rcsb pdb:2CG5|rcsb pdb:2JFD|rcsb pdb:2JFK|rcsb pdb:2PX6|rcsb pdb:3HHD|rcsb pdb:3TJM|rcsb pdb:4PIV|rcsb pdb:4W82|rcsb pdb:4W9N|rcsb pdb:4Z49|rcsb pdb:5C37|rcsb pdb:6NNA|reactome:R-HSA-163765|reactome:R-HSA-199220|reactome:R-HSA-2426168|reactome:R-HSA-75105|reactome:R-HSA-9029558|go:"GO:0047117"("enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) activity")|refseq:XP_011521840.1|dip:DIP-33681N	-	-	-	figure legend:Supplementary Table 1-2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2016/08/08	2018/04/06	rogid:Y/gCMNfRuvW/8zUT3Fvq2ZR9I8o9606	rogid:bQYEH/uQ6l+SPzLBDNCV5yP+yzs9606	rigid:0bkSr8P9cUiTRnAuQJAayRI1BM0	false	strep ii tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P49327	uniprotkb:Q8IV20	intact:EBI-356658|uniprotkb:Q4LE83|uniprotkb:Q13479|uniprotkb:Q16702|uniprotkb:Q6P4U5|uniprotkb:Q6SS02|uniprotkb:Q969R1|uniprotkb:Q96C68|uniprotkb:Q96IT0|ensembl:ENSP00000304592	intact:EBI-12508070|ensembl:ENSP00000391747|ensembl:ENSP00000317619|uniprotkb:A2A3Z6|uniprotkb:Q8N8X5	psi-mi:fas_human(display_long)|uniprotkb:FASN(gene name)|psi-mi:FASN(display_short)|uniprotkb:FAS(gene name synonym)|uniprotkb:Type I fatty acid synthase(gene name synonym)	psi-mi:lacc1_human(display_long)|uniprotkb:LACC1(gene name)|psi-mi:LACC1(display_short)|uniprotkb:C13orf31(gene name synonym)|uniprotkb:FAMIN(gene name synonym)|uniprotkb:Fatty acid metabolism-immunity nexus(gene name synonym)|uniprotkb:Adenosine deaminase LACC1(gene name synonym)|uniprotkb:Guanosine phosphorylase LACC1(gene name synonym)|uniprotkb:Laccase domain-containing protein 1(gene name synonym)|uniprotkb:S-methyl-5'-thioadenosine phosphorylase LACC1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Cader et al. (2016)	pubmed:27478939|imex:IM-26127	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12508397|imex:IM-26127-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004095.4|ensembl:ENSG00000169710(gene)|ensembl:ENST00000306749(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0002068"(glandular epithelial cell development)|go:"GO:0003723"(RNA binding)|go:"GO:0004313"([acyl-carrier-protein] S-acetyltransferase activity)|go:"GO:0004314"([acyl-carrier-protein] S-malonyltransferase activity)|go:"GO:0004315"(3-oxoacyl-[acyl-carrier-protein] synthase activity)|go:"GO:0004316"("3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity")|go:"GO:0004317"(3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity)|go:"GO:0004320"(oleoyl-[acyl-carrier-protein] hydrolase activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006084"(acetyl-CoA metabolic process)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0008611"(ether lipid biosynthetic process)|go:"GO:0008659"("(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity")|go:"GO:0008693"(3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity)|go:"GO:0016020"(membrane)|go:"GO:0016295"(myristoyl-[acyl-carrier-protein] hydrolase activity)|go:"GO:0016296"(palmitoyl-[acyl-carrier-protein] hydrolase activity)|go:"GO:0030223"(neutrophil differentiation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0030879"(mammary gland development)|go:"GO:0031177"(phosphopantetheine binding)|go:"GO:0042470"(melanosome)|go:"GO:0042587"(glycogen granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0047451"(3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0090557"(establishment of endothelial intestinal barrier)|go:"GO:0102131"(obsolete 3-oxo-glutaryl-[acp] methyl ester reductase activity)|go:"GO:0102132"(obsolete 3-oxo-pimeloyl-[acp] methyl ester reductase activity)|interpro:IPR001031(Thioesterase)|interpro:IPR001227(Acyl transferase region)|interpro:IPR006162(Phosphopantetheine attachment site)|interpro:IPR009081(Acyl carrier protein-like)|interpro:IPR011032(GroES-like)|interpro:IPR013149(Alcohol dehydrogenase, zinc-binding)|interpro:IPR013217(Methyltransferase type 12)|interpro:IPR013968(Polyketide synthase, KR)|interpro:IPR014030(Beta-ketoacyl synthase, N-terminal)|interpro:IPR014031(Beta-ketoacyl synthase, C-terminal)|interpro:IPR014043(Acyl transferase)|interpro:IPR016035(Acyl transferase/acyl hydrolase/lysophospholipase)|interpro:IPR016036(Malonyl-CoA ACP transacylase, ACP-binding)|interpro:IPR016039(Thiolase-like)|interpro:IPR018201|interpro:IPR020806|interpro:IPR020807|interpro:IPR020841|interpro:IPR020843|interpro:IPR029058|interpro:IPR029063|interpro:IPR032821|interpro:IPR036291|interpro:IPR036736|interpro:IPR042104|mint:P49327|rcsb pdb:1XKT|rcsb pdb:2CG5|rcsb pdb:2JFD|rcsb pdb:2JFK|rcsb pdb:2PX6|rcsb pdb:3HHD|rcsb pdb:3TJM|rcsb pdb:4PIV|rcsb pdb:4W82|rcsb pdb:4W9N|rcsb pdb:4Z49|rcsb pdb:5C37|rcsb pdb:6NNA|reactome:R-HSA-163765|reactome:R-HSA-199220|reactome:R-HSA-2426168|reactome:R-HSA-75105|reactome:R-HSA-9029558|go:"GO:0047117"("enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) activity")|refseq:XP_011521840.1|dip:DIP-33681N	ensembl:ENST00000325686(transcript)|ensembl:ENST00000441843(transcript)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0004000"(adenosine deaminase activity)|go:"GO:0004731"(purine-nucleoside phosphorylase activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006954"(inflammatory response)|go:"GO:0017061"(S-methyl-5-thioadenosine phosphorylase activity)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0045087"(innate immune response)|go:"GO:0047975"(guanosine phosphorylase activity)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:1900542"(regulation of purine nucleotide metabolic process)|interpro:IPR003730(Protein of unknown function DUF152)|interpro:IPR011324(Cytotoxic necrotizing factor-like, catalytic)|interpro:IPR038371|ensembl:ENSG00000179630(gene)|refseq:NP_001121775.1|refseq:NP_694950.2|refseq:XP_005266318.1|refseq:XP_006719829.1|refseq:XP_011533235.1|refseq:XP_011533236.1|refseq:XP_016875883.1	-	-	-	figure legend:1A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-macrophage)|taxid:9606(Human macrophages)	-	2016/08/08	2016/08/17	rogid:bQYEH/uQ6l+SPzLBDNCV5yP+yzs9606	rogid:Y/gCMNfRuvW/8zUT3Fvq2ZR9I8o9606	rigid:F5JjMPGS+lhJyb9Agi2Y486oee4	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P49327	uniprotkb:Q8IV20	intact:EBI-356658|uniprotkb:Q4LE83|uniprotkb:Q13479|uniprotkb:Q16702|uniprotkb:Q6P4U5|uniprotkb:Q6SS02|uniprotkb:Q969R1|uniprotkb:Q96C68|uniprotkb:Q96IT0|ensembl:ENSP00000304592	intact:EBI-12508070|ensembl:ENSP00000391747|ensembl:ENSP00000317619|uniprotkb:A2A3Z6|uniprotkb:Q8N8X5	psi-mi:fas_human(display_long)|uniprotkb:FASN(gene name)|psi-mi:FASN(display_short)|uniprotkb:FAS(gene name synonym)|uniprotkb:Type I fatty acid synthase(gene name synonym)	psi-mi:lacc1_human(display_long)|uniprotkb:LACC1(gene name)|psi-mi:LACC1(display_short)|uniprotkb:C13orf31(gene name synonym)|uniprotkb:FAMIN(gene name synonym)|uniprotkb:Fatty acid metabolism-immunity nexus(gene name synonym)|uniprotkb:Adenosine deaminase LACC1(gene name synonym)|uniprotkb:Guanosine phosphorylase LACC1(gene name synonym)|uniprotkb:Laccase domain-containing protein 1(gene name synonym)|uniprotkb:S-methyl-5'-thioadenosine phosphorylase LACC1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Cader et al. (2016)	pubmed:27478939|imex:IM-26127	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12508402|imex:IM-26127-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004095.4|ensembl:ENSG00000169710(gene)|ensembl:ENST00000306749(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0002068"(glandular epithelial cell development)|go:"GO:0003723"(RNA binding)|go:"GO:0004313"([acyl-carrier-protein] S-acetyltransferase activity)|go:"GO:0004314"([acyl-carrier-protein] S-malonyltransferase activity)|go:"GO:0004315"(3-oxoacyl-[acyl-carrier-protein] synthase activity)|go:"GO:0004316"("3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity")|go:"GO:0004317"(3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity)|go:"GO:0004320"(oleoyl-[acyl-carrier-protein] hydrolase activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006084"(acetyl-CoA metabolic process)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0008611"(ether lipid biosynthetic process)|go:"GO:0008659"("(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity")|go:"GO:0008693"(3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity)|go:"GO:0016020"(membrane)|go:"GO:0016295"(myristoyl-[acyl-carrier-protein] hydrolase activity)|go:"GO:0016296"(palmitoyl-[acyl-carrier-protein] hydrolase activity)|go:"GO:0030223"(neutrophil differentiation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0030879"(mammary gland development)|go:"GO:0031177"(phosphopantetheine binding)|go:"GO:0042470"(melanosome)|go:"GO:0042587"(glycogen granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0047451"(3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0090557"(establishment of endothelial intestinal barrier)|go:"GO:0102131"(obsolete 3-oxo-glutaryl-[acp] methyl ester reductase activity)|go:"GO:0102132"(obsolete 3-oxo-pimeloyl-[acp] methyl ester reductase activity)|interpro:IPR001031(Thioesterase)|interpro:IPR001227(Acyl transferase region)|interpro:IPR006162(Phosphopantetheine attachment site)|interpro:IPR009081(Acyl carrier protein-like)|interpro:IPR011032(GroES-like)|interpro:IPR013149(Alcohol dehydrogenase, zinc-binding)|interpro:IPR013217(Methyltransferase type 12)|interpro:IPR013968(Polyketide synthase, KR)|interpro:IPR014030(Beta-ketoacyl synthase, N-terminal)|interpro:IPR014031(Beta-ketoacyl synthase, C-terminal)|interpro:IPR014043(Acyl transferase)|interpro:IPR016035(Acyl transferase/acyl hydrolase/lysophospholipase)|interpro:IPR016036(Malonyl-CoA ACP transacylase, ACP-binding)|interpro:IPR016039(Thiolase-like)|interpro:IPR018201|interpro:IPR020806|interpro:IPR020807|interpro:IPR020841|interpro:IPR020843|interpro:IPR029058|interpro:IPR029063|interpro:IPR032821|interpro:IPR036291|interpro:IPR036736|interpro:IPR042104|mint:P49327|rcsb pdb:1XKT|rcsb pdb:2CG5|rcsb pdb:2JFD|rcsb pdb:2JFK|rcsb pdb:2PX6|rcsb pdb:3HHD|rcsb pdb:3TJM|rcsb pdb:4PIV|rcsb pdb:4W82|rcsb pdb:4W9N|rcsb pdb:4Z49|rcsb pdb:5C37|rcsb pdb:6NNA|reactome:R-HSA-163765|reactome:R-HSA-199220|reactome:R-HSA-2426168|reactome:R-HSA-75105|reactome:R-HSA-9029558|go:"GO:0047117"("enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) activity")|refseq:XP_011521840.1|dip:DIP-33681N	ensembl:ENST00000325686(transcript)|ensembl:ENST00000441843(transcript)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0004000"(adenosine deaminase activity)|go:"GO:0004731"(purine-nucleoside phosphorylase activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006954"(inflammatory response)|go:"GO:0017061"(S-methyl-5-thioadenosine phosphorylase activity)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0045087"(innate immune response)|go:"GO:0047975"(guanosine phosphorylase activity)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:1900542"(regulation of purine nucleotide metabolic process)|interpro:IPR003730(Protein of unknown function DUF152)|interpro:IPR011324(Cytotoxic necrotizing factor-like, catalytic)|interpro:IPR038371|ensembl:ENSG00000179630(gene)|refseq:NP_001121775.1|refseq:NP_694950.2|refseq:XP_005266318.1|refseq:XP_006719829.1|refseq:XP_011533235.1|refseq:XP_011533236.1|refseq:XP_016875883.1	-	-	-	figure legend:1A-2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-macrophage)|taxid:9606(Human macrophages)	-	2016/08/08	2016/08/17	rogid:bQYEH/uQ6l+SPzLBDNCV5yP+yzs9606	rogid:Y/gCMNfRuvW/8zUT3Fvq2ZR9I8o9606	rigid:F5JjMPGS+lhJyb9Agi2Y486oee4	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P49327	uniprotkb:Q8IV20	intact:EBI-356658|uniprotkb:Q4LE83|uniprotkb:Q13479|uniprotkb:Q16702|uniprotkb:Q6P4U5|uniprotkb:Q6SS02|uniprotkb:Q969R1|uniprotkb:Q96C68|uniprotkb:Q96IT0|ensembl:ENSP00000304592	intact:EBI-12508070|ensembl:ENSP00000391747|ensembl:ENSP00000317619|uniprotkb:A2A3Z6|uniprotkb:Q8N8X5	psi-mi:fas_human(display_long)|uniprotkb:FASN(gene name)|psi-mi:FASN(display_short)|uniprotkb:FAS(gene name synonym)|uniprotkb:Type I fatty acid synthase(gene name synonym)	psi-mi:lacc1_human(display_long)|uniprotkb:LACC1(gene name)|psi-mi:LACC1(display_short)|uniprotkb:C13orf31(gene name synonym)|uniprotkb:FAMIN(gene name synonym)|uniprotkb:Fatty acid metabolism-immunity nexus(gene name synonym)|uniprotkb:Adenosine deaminase LACC1(gene name synonym)|uniprotkb:Guanosine phosphorylase LACC1(gene name synonym)|uniprotkb:Laccase domain-containing protein 1(gene name synonym)|uniprotkb:S-methyl-5'-thioadenosine phosphorylase LACC1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Cader et al. (2016)	pubmed:27478939|imex:IM-26127	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12508416|imex:IM-26127-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004095.4|ensembl:ENSG00000169710(gene)|ensembl:ENST00000306749(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0002068"(glandular epithelial cell development)|go:"GO:0003723"(RNA binding)|go:"GO:0004313"([acyl-carrier-protein] S-acetyltransferase activity)|go:"GO:0004314"([acyl-carrier-protein] S-malonyltransferase activity)|go:"GO:0004315"(3-oxoacyl-[acyl-carrier-protein] synthase activity)|go:"GO:0004316"("3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity")|go:"GO:0004317"(3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity)|go:"GO:0004320"(oleoyl-[acyl-carrier-protein] hydrolase activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006084"(acetyl-CoA metabolic process)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0008611"(ether lipid biosynthetic process)|go:"GO:0008659"("(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity")|go:"GO:0008693"(3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity)|go:"GO:0016020"(membrane)|go:"GO:0016295"(myristoyl-[acyl-carrier-protein] hydrolase activity)|go:"GO:0016296"(palmitoyl-[acyl-carrier-protein] hydrolase activity)|go:"GO:0030223"(neutrophil differentiation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0030879"(mammary gland development)|go:"GO:0031177"(phosphopantetheine binding)|go:"GO:0042470"(melanosome)|go:"GO:0042587"(glycogen granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0047451"(3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0090557"(establishment of endothelial intestinal barrier)|go:"GO:0102131"(obsolete 3-oxo-glutaryl-[acp] methyl ester reductase activity)|go:"GO:0102132"(obsolete 3-oxo-pimeloyl-[acp] methyl ester reductase activity)|interpro:IPR001031(Thioesterase)|interpro:IPR001227(Acyl transferase region)|interpro:IPR006162(Phosphopantetheine attachment site)|interpro:IPR009081(Acyl carrier protein-like)|interpro:IPR011032(GroES-like)|interpro:IPR013149(Alcohol dehydrogenase, zinc-binding)|interpro:IPR013217(Methyltransferase type 12)|interpro:IPR013968(Polyketide synthase, KR)|interpro:IPR014030(Beta-ketoacyl synthase, N-terminal)|interpro:IPR014031(Beta-ketoacyl synthase, C-terminal)|interpro:IPR014043(Acyl transferase)|interpro:IPR016035(Acyl transferase/acyl hydrolase/lysophospholipase)|interpro:IPR016036(Malonyl-CoA ACP transacylase, ACP-binding)|interpro:IPR016039(Thiolase-like)|interpro:IPR018201|interpro:IPR020806|interpro:IPR020807|interpro:IPR020841|interpro:IPR020843|interpro:IPR029058|interpro:IPR029063|interpro:IPR032821|interpro:IPR036291|interpro:IPR036736|interpro:IPR042104|mint:P49327|rcsb pdb:1XKT|rcsb pdb:2CG5|rcsb pdb:2JFD|rcsb pdb:2JFK|rcsb pdb:2PX6|rcsb pdb:3HHD|rcsb pdb:3TJM|rcsb pdb:4PIV|rcsb pdb:4W82|rcsb pdb:4W9N|rcsb pdb:4Z49|rcsb pdb:5C37|rcsb pdb:6NNA|reactome:R-HSA-163765|reactome:R-HSA-199220|reactome:R-HSA-2426168|reactome:R-HSA-75105|reactome:R-HSA-9029558|go:"GO:0047117"("enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) activity")|refseq:XP_011521840.1|dip:DIP-33681N	ensembl:ENST00000325686(transcript)|ensembl:ENST00000441843(transcript)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0004000"(adenosine deaminase activity)|go:"GO:0004731"(purine-nucleoside phosphorylase activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006954"(inflammatory response)|go:"GO:0017061"(S-methyl-5-thioadenosine phosphorylase activity)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0045087"(innate immune response)|go:"GO:0047975"(guanosine phosphorylase activity)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:1900542"(regulation of purine nucleotide metabolic process)|interpro:IPR003730(Protein of unknown function DUF152)|interpro:IPR011324(Cytotoxic necrotizing factor-like, catalytic)|interpro:IPR038371|ensembl:ENSG00000179630(gene)|refseq:NP_001121775.1|refseq:NP_694950.2|refseq:XP_005266318.1|refseq:XP_006719829.1|refseq:XP_011533235.1|refseq:XP_011533236.1|refseq:XP_016875883.1	-	-	-	figure legend:1A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-u937)|taxid:9606(Homo sapiens histiocytic lymphoma cells)	-	2016/08/08	2016/08/17	rogid:bQYEH/uQ6l+SPzLBDNCV5yP+yzs9606	rogid:Y/gCMNfRuvW/8zUT3Fvq2ZR9I8o9606	rigid:F5JjMPGS+lhJyb9Agi2Y486oee4	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P49327	uniprotkb:Q8IV20	intact:EBI-356658|uniprotkb:Q4LE83|uniprotkb:Q13479|uniprotkb:Q16702|uniprotkb:Q6P4U5|uniprotkb:Q6SS02|uniprotkb:Q969R1|uniprotkb:Q96C68|uniprotkb:Q96IT0|ensembl:ENSP00000304592	intact:EBI-12508070|ensembl:ENSP00000391747|ensembl:ENSP00000317619|uniprotkb:A2A3Z6|uniprotkb:Q8N8X5	psi-mi:fas_human(display_long)|uniprotkb:FASN(gene name)|psi-mi:FASN(display_short)|uniprotkb:FAS(gene name synonym)|uniprotkb:Type I fatty acid synthase(gene name synonym)	psi-mi:lacc1_human(display_long)|uniprotkb:LACC1(gene name)|psi-mi:LACC1(display_short)|uniprotkb:C13orf31(gene name synonym)|uniprotkb:FAMIN(gene name synonym)|uniprotkb:Fatty acid metabolism-immunity nexus(gene name synonym)|uniprotkb:Adenosine deaminase LACC1(gene name synonym)|uniprotkb:Guanosine phosphorylase LACC1(gene name synonym)|uniprotkb:Laccase domain-containing protein 1(gene name synonym)|uniprotkb:S-methyl-5'-thioadenosine phosphorylase LACC1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Cader et al. (2016)	pubmed:27478939|imex:IM-26127	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12508429|imex:IM-26127-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004095.4|ensembl:ENSG00000169710(gene)|ensembl:ENST00000306749(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0002068"(glandular epithelial cell development)|go:"GO:0003723"(RNA binding)|go:"GO:0004313"([acyl-carrier-protein] S-acetyltransferase activity)|go:"GO:0004314"([acyl-carrier-protein] S-malonyltransferase activity)|go:"GO:0004315"(3-oxoacyl-[acyl-carrier-protein] synthase activity)|go:"GO:0004316"("3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity")|go:"GO:0004317"(3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity)|go:"GO:0004320"(oleoyl-[acyl-carrier-protein] hydrolase activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006084"(acetyl-CoA metabolic process)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0008611"(ether lipid biosynthetic process)|go:"GO:0008659"("(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity")|go:"GO:0008693"(3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity)|go:"GO:0016020"(membrane)|go:"GO:0016295"(myristoyl-[acyl-carrier-protein] hydrolase activity)|go:"GO:0016296"(palmitoyl-[acyl-carrier-protein] hydrolase activity)|go:"GO:0030223"(neutrophil differentiation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0030879"(mammary gland development)|go:"GO:0031177"(phosphopantetheine binding)|go:"GO:0042470"(melanosome)|go:"GO:0042587"(glycogen granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0047451"(3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0090557"(establishment of endothelial intestinal barrier)|go:"GO:0102131"(obsolete 3-oxo-glutaryl-[acp] methyl ester reductase activity)|go:"GO:0102132"(obsolete 3-oxo-pimeloyl-[acp] methyl ester reductase activity)|interpro:IPR001031(Thioesterase)|interpro:IPR001227(Acyl transferase region)|interpro:IPR006162(Phosphopantetheine attachment site)|interpro:IPR009081(Acyl carrier protein-like)|interpro:IPR011032(GroES-like)|interpro:IPR013149(Alcohol dehydrogenase, zinc-binding)|interpro:IPR013217(Methyltransferase type 12)|interpro:IPR013968(Polyketide synthase, KR)|interpro:IPR014030(Beta-ketoacyl synthase, N-terminal)|interpro:IPR014031(Beta-ketoacyl synthase, C-terminal)|interpro:IPR014043(Acyl transferase)|interpro:IPR016035(Acyl transferase/acyl hydrolase/lysophospholipase)|interpro:IPR016036(Malonyl-CoA ACP transacylase, ACP-binding)|interpro:IPR016039(Thiolase-like)|interpro:IPR018201|interpro:IPR020806|interpro:IPR020807|interpro:IPR020841|interpro:IPR020843|interpro:IPR029058|interpro:IPR029063|interpro:IPR032821|interpro:IPR036291|interpro:IPR036736|interpro:IPR042104|mint:P49327|rcsb pdb:1XKT|rcsb pdb:2CG5|rcsb pdb:2JFD|rcsb pdb:2JFK|rcsb pdb:2PX6|rcsb pdb:3HHD|rcsb pdb:3TJM|rcsb pdb:4PIV|rcsb pdb:4W82|rcsb pdb:4W9N|rcsb pdb:4Z49|rcsb pdb:5C37|rcsb pdb:6NNA|reactome:R-HSA-163765|reactome:R-HSA-199220|reactome:R-HSA-2426168|reactome:R-HSA-75105|reactome:R-HSA-9029558|go:"GO:0047117"("enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) activity")|refseq:XP_011521840.1|dip:DIP-33681N	ensembl:ENST00000325686(transcript)|ensembl:ENST00000441843(transcript)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0004000"(adenosine deaminase activity)|go:"GO:0004731"(purine-nucleoside phosphorylase activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006954"(inflammatory response)|go:"GO:0017061"(S-methyl-5-thioadenosine phosphorylase activity)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0045087"(innate immune response)|go:"GO:0047975"(guanosine phosphorylase activity)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:1900542"(regulation of purine nucleotide metabolic process)|interpro:IPR003730(Protein of unknown function DUF152)|interpro:IPR011324(Cytotoxic necrotizing factor-like, catalytic)|interpro:IPR038371|ensembl:ENSG00000179630(gene)|refseq:NP_001121775.1|refseq:NP_694950.2|refseq:XP_005266318.1|refseq:XP_006719829.1|refseq:XP_011533235.1|refseq:XP_011533236.1|refseq:XP_016875883.1	-	-	-	figure legend:1A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-thp-1)|taxid:9606(Homo sapiens acute monocytic leukemia cells)	-	2016/08/08	2016/08/17	rogid:bQYEH/uQ6l+SPzLBDNCV5yP+yzs9606	rogid:Y/gCMNfRuvW/8zUT3Fvq2ZR9I8o9606	rigid:F5JjMPGS+lhJyb9Agi2Y486oee4	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P49327	uniprotkb:Q8IV20	intact:EBI-356658|uniprotkb:Q4LE83|uniprotkb:Q13479|uniprotkb:Q16702|uniprotkb:Q6P4U5|uniprotkb:Q6SS02|uniprotkb:Q969R1|uniprotkb:Q96C68|uniprotkb:Q96IT0|ensembl:ENSP00000304592	intact:EBI-12508070|ensembl:ENSP00000391747|ensembl:ENSP00000317619|uniprotkb:A2A3Z6|uniprotkb:Q8N8X5	psi-mi:fas_human(display_long)|uniprotkb:FASN(gene name)|psi-mi:FASN(display_short)|uniprotkb:FAS(gene name synonym)|uniprotkb:Type I fatty acid synthase(gene name synonym)	psi-mi:lacc1_human(display_long)|uniprotkb:LACC1(gene name)|psi-mi:LACC1(display_short)|uniprotkb:C13orf31(gene name synonym)|uniprotkb:FAMIN(gene name synonym)|uniprotkb:Fatty acid metabolism-immunity nexus(gene name synonym)|uniprotkb:Adenosine deaminase LACC1(gene name synonym)|uniprotkb:Guanosine phosphorylase LACC1(gene name synonym)|uniprotkb:Laccase domain-containing protein 1(gene name synonym)|uniprotkb:S-methyl-5'-thioadenosine phosphorylase LACC1(gene name synonym)	psi-mi:"MI:0813"(proximity ligation assay)	Cader et al. (2016)	pubmed:27478939|imex:IM-26127	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12508440|imex:IM-26127-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004095.4|ensembl:ENSG00000169710(gene)|ensembl:ENST00000306749(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0002068"(glandular epithelial cell development)|go:"GO:0003723"(RNA binding)|go:"GO:0004313"([acyl-carrier-protein] S-acetyltransferase activity)|go:"GO:0004314"([acyl-carrier-protein] S-malonyltransferase activity)|go:"GO:0004315"(3-oxoacyl-[acyl-carrier-protein] synthase activity)|go:"GO:0004316"("3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity")|go:"GO:0004317"(3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity)|go:"GO:0004320"(oleoyl-[acyl-carrier-protein] hydrolase activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006084"(acetyl-CoA metabolic process)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0008611"(ether lipid biosynthetic process)|go:"GO:0008659"("(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity")|go:"GO:0008693"(3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity)|go:"GO:0016020"(membrane)|go:"GO:0016295"(myristoyl-[acyl-carrier-protein] hydrolase activity)|go:"GO:0016296"(palmitoyl-[acyl-carrier-protein] hydrolase activity)|go:"GO:0030223"(neutrophil differentiation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0030879"(mammary gland development)|go:"GO:0031177"(phosphopantetheine binding)|go:"GO:0042470"(melanosome)|go:"GO:0042587"(glycogen granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0047451"(3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0090557"(establishment of endothelial intestinal barrier)|go:"GO:0102131"(obsolete 3-oxo-glutaryl-[acp] methyl ester reductase activity)|go:"GO:0102132"(obsolete 3-oxo-pimeloyl-[acp] methyl ester reductase activity)|interpro:IPR001031(Thioesterase)|interpro:IPR001227(Acyl transferase region)|interpro:IPR006162(Phosphopantetheine attachment site)|interpro:IPR009081(Acyl carrier protein-like)|interpro:IPR011032(GroES-like)|interpro:IPR013149(Alcohol dehydrogenase, zinc-binding)|interpro:IPR013217(Methyltransferase type 12)|interpro:IPR013968(Polyketide synthase, KR)|interpro:IPR014030(Beta-ketoacyl synthase, N-terminal)|interpro:IPR014031(Beta-ketoacyl synthase, C-terminal)|interpro:IPR014043(Acyl transferase)|interpro:IPR016035(Acyl transferase/acyl hydrolase/lysophospholipase)|interpro:IPR016036(Malonyl-CoA ACP transacylase, ACP-binding)|interpro:IPR016039(Thiolase-like)|interpro:IPR018201|interpro:IPR020806|interpro:IPR020807|interpro:IPR020841|interpro:IPR020843|interpro:IPR029058|interpro:IPR029063|interpro:IPR032821|interpro:IPR036291|interpro:IPR036736|interpro:IPR042104|mint:P49327|rcsb pdb:1XKT|rcsb pdb:2CG5|rcsb pdb:2JFD|rcsb pdb:2JFK|rcsb pdb:2PX6|rcsb pdb:3HHD|rcsb pdb:3TJM|rcsb pdb:4PIV|rcsb pdb:4W82|rcsb pdb:4W9N|rcsb pdb:4Z49|rcsb pdb:5C37|rcsb pdb:6NNA|reactome:R-HSA-163765|reactome:R-HSA-199220|reactome:R-HSA-2426168|reactome:R-HSA-75105|reactome:R-HSA-9029558|go:"GO:0047117"("enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) activity")|refseq:XP_011521840.1|dip:DIP-33681N	ensembl:ENST00000325686(transcript)|ensembl:ENST00000441843(transcript)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0004000"(adenosine deaminase activity)|go:"GO:0004731"(purine-nucleoside phosphorylase activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006954"(inflammatory response)|go:"GO:0017061"(S-methyl-5-thioadenosine phosphorylase activity)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0045087"(innate immune response)|go:"GO:0047975"(guanosine phosphorylase activity)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:1900542"(regulation of purine nucleotide metabolic process)|interpro:IPR003730(Protein of unknown function DUF152)|interpro:IPR011324(Cytotoxic necrotizing factor-like, catalytic)|interpro:IPR038371|ensembl:ENSG00000179630(gene)|refseq:NP_001121775.1|refseq:NP_694950.2|refseq:XP_005266318.1|refseq:XP_006719829.1|refseq:XP_011533235.1|refseq:XP_011533236.1|refseq:XP_016875883.1	-	-	-	figure legend:1B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-thp-1)|taxid:9606(Homo sapiens acute monocytic leukemia cells)	-	2016/08/08	2016/08/17	rogid:bQYEH/uQ6l+SPzLBDNCV5yP+yzs9606	rogid:Y/gCMNfRuvW/8zUT3Fvq2ZR9I8o9606	rigid:F5JjMPGS+lhJyb9Agi2Y486oee4	false	-	-	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:P28288	uniprotkb:Q8IV20	intact:EBI-80992|ensembl:ENSP00000359233|uniprotkb:Q15271|uniprotkb:Q9H529|uniprotkb:Q6NUN5|uniprotkb:Q96DA3|uniprotkb:D3DT46	intact:EBI-12508070|ensembl:ENSP00000391747|ensembl:ENSP00000317619|uniprotkb:A2A3Z6|uniprotkb:Q8N8X5	psi-mi:abcd3_human(display_long)|uniprotkb:ABCD3(gene name)|psi-mi:ABCD3(display_short)|uniprotkb:PMP70(gene name synonym)|uniprotkb:PXMP1(gene name synonym)|uniprotkb:70 kDa peroxisomal membrane protein(gene name synonym)	psi-mi:lacc1_human(display_long)|uniprotkb:LACC1(gene name)|psi-mi:LACC1(display_short)|uniprotkb:C13orf31(gene name synonym)|uniprotkb:FAMIN(gene name synonym)|uniprotkb:Fatty acid metabolism-immunity nexus(gene name synonym)|uniprotkb:Adenosine deaminase LACC1(gene name synonym)|uniprotkb:Guanosine phosphorylase LACC1(gene name synonym)|uniprotkb:Laccase domain-containing protein 1(gene name synonym)|uniprotkb:S-methyl-5'-thioadenosine phosphorylase LACC1(gene name synonym)	psi-mi:"MI:0813"(proximity ligation assay)	Cader et al. (2016)	pubmed:27478939|imex:IM-26127	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12508514|imex:IM-26127-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000117528(gene)|ensembl:ENST00000370214(transcript)|go:"GO:0005324"(long-chain fatty acid transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0007031"(peroxisome organization)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0015910"(long-chain fatty acid import into peroxisome)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0042493"|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|refseq:NP_001116146.1|refseq:NP_002849.1|go:"GO:0042760"(very long-chain fatty acid catabolic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043621"(protein self-association)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR005283(Peroxysomal long chain fatty acyl transporter)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR017871|interpro:IPR027417|interpro:IPR036640|mint:P28288|reactome:R-HSA-1369062|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9603798	ensembl:ENST00000325686(transcript)|ensembl:ENST00000441843(transcript)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0004000"(adenosine deaminase activity)|go:"GO:0004731"(purine-nucleoside phosphorylase activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006954"(inflammatory response)|go:"GO:0017061"(S-methyl-5-thioadenosine phosphorylase activity)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0045087"(innate immune response)|go:"GO:0047975"(guanosine phosphorylase activity)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:1900542"(regulation of purine nucleotide metabolic process)|interpro:IPR003730(Protein of unknown function DUF152)|interpro:IPR011324(Cytotoxic necrotizing factor-like, catalytic)|interpro:IPR038371|ensembl:ENSG00000179630(gene)|refseq:NP_001121775.1|refseq:NP_694950.2|refseq:XP_005266318.1|refseq:XP_006719829.1|refseq:XP_011533235.1|refseq:XP_011533236.1|refseq:XP_016875883.1	go:"GO:0005777"(peroxisome)	-	-	figure legend:1E, Supp 2F|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-thp-1)|taxid:9606(Homo sapiens acute monocytic leukemia cells)	-	2016/08/08	2016/08/17	rogid:aUTR1BDihIx1JxtsC5V4vmFAwA49606	rogid:Y/gCMNfRuvW/8zUT3Fvq2ZR9I8o9606	rigid:wrBohZrTSK5+27JLv5ZvuP7J2hI	false	-	-	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:P04040	uniprotkb:Q8IV20	intact:EBI-2432181|uniprotkb:A8K6C0|uniprotkb:B2RCZ9|uniprotkb:Q9UC85|uniprotkb:Q2M1U4|uniprotkb:Q4VXX5|uniprotkb:Q9BWT9|uniprotkb:D3DR07|ensembl:ENSP00000241052	intact:EBI-12508070|ensembl:ENSP00000391747|ensembl:ENSP00000317619|uniprotkb:A2A3Z6|uniprotkb:Q8N8X5	psi-mi:cata_human(display_long)|uniprotkb:CAT(gene name)|psi-mi:CAT(display_short)	psi-mi:lacc1_human(display_long)|uniprotkb:LACC1(gene name)|psi-mi:LACC1(display_short)|uniprotkb:C13orf31(gene name synonym)|uniprotkb:FAMIN(gene name synonym)|uniprotkb:Fatty acid metabolism-immunity nexus(gene name synonym)|uniprotkb:Adenosine deaminase LACC1(gene name synonym)|uniprotkb:Guanosine phosphorylase LACC1(gene name synonym)|uniprotkb:Laccase domain-containing protein 1(gene name synonym)|uniprotkb:S-methyl-5'-thioadenosine phosphorylase LACC1(gene name synonym)	psi-mi:"MI:0813"(proximity ligation assay)	Cader et al. (2016)	pubmed:27478939|imex:IM-26127	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12508882|imex:IM-26127-19	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001743.1|ensembl:ENSG00000121691(gene)|ensembl:ENST00000241052(transcript)|go:"GO:0000268"(peroxisome targeting sequence binding)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001666"(response to hypoxia)|go:"GO:0004046"(aminoacylase activity)|go:"GO:0004096"(catalase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005764"(lysosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0007568"(aging)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0009060"(aerobic respiration)|go:"GO:0009642"(response to light intensity)|go:"GO:0009650"(UV protection)|go:"GO:0010193"(response to ozone)|go:"GO:0010288"(response to lead ion)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014823"(response to activity)|go:"GO:0014854"(response to inactivity)|go:"GO:0016020"(membrane)|go:"GO:0016209"(antioxidant activity)|go:"GO:0016684"(oxidoreductase activity, acting on peroxide as acceptor)|go:"GO:0019899"(enzyme binding)|go:"GO:0020027"(hemoglobin metabolic process)|go:"GO:0020037"(heme binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032355"(response to estradiol)|go:"GO:0032868"(response to insulin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033189"(response to vitamin A)|go:"GO:0033197"(response to vitamin E)|go:"GO:0033591"(response to L-ascorbic acid)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045471"(response to ethanol)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0046872"(metal ion binding)|go:"GO:0050661"(NADP binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070542"(response to fatty acid)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0080184"(response to phenylpropanoid)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR002226(Catalase)|interpro:IPR010582(Catalase-related)|interpro:IPR011614(Catalase, N-terminal)|interpro:IPR018028|interpro:IPR020835|interpro:IPR024708|interpro:IPR024711|interpro:IPR040333|mint:P04040|rcsb pdb:1DGB|rcsb pdb:1DGF|rcsb pdb:1DGG|rcsb pdb:1DGH|rcsb pdb:1F4J|rcsb pdb:1QQW|reactome:R-HSA-3299685|reactome:R-HSA-6798695|reactome:R-HSA-9033241|reactome:R-HSA-9615017	ensembl:ENST00000325686(transcript)|ensembl:ENST00000441843(transcript)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0004000"(adenosine deaminase activity)|go:"GO:0004731"(purine-nucleoside phosphorylase activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006954"(inflammatory response)|go:"GO:0017061"(S-methyl-5-thioadenosine phosphorylase activity)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0045087"(innate immune response)|go:"GO:0047975"(guanosine phosphorylase activity)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:1900542"(regulation of purine nucleotide metabolic process)|interpro:IPR003730(Protein of unknown function DUF152)|interpro:IPR011324(Cytotoxic necrotizing factor-like, catalytic)|interpro:IPR038371|ensembl:ENSG00000179630(gene)|refseq:NP_001121775.1|refseq:NP_694950.2|refseq:XP_005266318.1|refseq:XP_006719829.1|refseq:XP_011533235.1|refseq:XP_011533236.1|refseq:XP_016875883.1	-	-	-	figure legend:Supp 2F-2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-thp-1)|taxid:9606(Homo sapiens acute monocytic leukemia cells)	-	2016/08/08	2016/08/18	rogid:IWdPQIuCq9vCj8I0HmshkJwAAqg9606	rogid:Y/gCMNfRuvW/8zUT3Fvq2ZR9I8o9606	rigid:ILWA2/n0BZ4cmvi1h/RTV0JMOZo	false	-	-	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:P49327	uniprotkb:Q8IV20	intact:EBI-356658|uniprotkb:Q4LE83|uniprotkb:Q13479|uniprotkb:Q16702|uniprotkb:Q6P4U5|uniprotkb:Q6SS02|uniprotkb:Q969R1|uniprotkb:Q96C68|uniprotkb:Q96IT0|ensembl:ENSP00000304592	intact:EBI-12508070|ensembl:ENSP00000391747|ensembl:ENSP00000317619|uniprotkb:A2A3Z6|uniprotkb:Q8N8X5	psi-mi:fas_human(display_long)|uniprotkb:FASN(gene name)|psi-mi:FASN(display_short)|uniprotkb:FAS(gene name synonym)|uniprotkb:Type I fatty acid synthase(gene name synonym)	psi-mi:lacc1_human(display_long)|uniprotkb:LACC1(gene name)|psi-mi:LACC1(display_short)|uniprotkb:C13orf31(gene name synonym)|uniprotkb:FAMIN(gene name synonym)|uniprotkb:Fatty acid metabolism-immunity nexus(gene name synonym)|uniprotkb:Adenosine deaminase LACC1(gene name synonym)|uniprotkb:Guanosine phosphorylase LACC1(gene name synonym)|uniprotkb:Laccase domain-containing protein 1(gene name synonym)|uniprotkb:S-methyl-5'-thioadenosine phosphorylase LACC1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Cader et al. (2016)	pubmed:27478939|imex:IM-26127	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12508452|imex:IM-26127-23	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004095.4|ensembl:ENSG00000169710(gene)|ensembl:ENST00000306749(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0002068"(glandular epithelial cell development)|go:"GO:0003723"(RNA binding)|go:"GO:0004313"([acyl-carrier-protein] S-acetyltransferase activity)|go:"GO:0004314"([acyl-carrier-protein] S-malonyltransferase activity)|go:"GO:0004315"(3-oxoacyl-[acyl-carrier-protein] synthase activity)|go:"GO:0004316"("3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity")|go:"GO:0004317"(3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity)|go:"GO:0004320"(oleoyl-[acyl-carrier-protein] hydrolase activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006084"(acetyl-CoA metabolic process)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0008611"(ether lipid biosynthetic process)|go:"GO:0008659"("(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity")|go:"GO:0008693"(3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity)|go:"GO:0016020"(membrane)|go:"GO:0016295"(myristoyl-[acyl-carrier-protein] hydrolase activity)|go:"GO:0016296"(palmitoyl-[acyl-carrier-protein] hydrolase activity)|go:"GO:0030223"(neutrophil differentiation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0030879"(mammary gland development)|go:"GO:0031177"(phosphopantetheine binding)|go:"GO:0042470"(melanosome)|go:"GO:0042587"(glycogen granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0047451"(3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0090557"(establishment of endothelial intestinal barrier)|go:"GO:0102131"(obsolete 3-oxo-glutaryl-[acp] methyl ester reductase activity)|go:"GO:0102132"(obsolete 3-oxo-pimeloyl-[acp] methyl ester reductase activity)|interpro:IPR001031(Thioesterase)|interpro:IPR001227(Acyl transferase region)|interpro:IPR006162(Phosphopantetheine attachment site)|interpro:IPR009081(Acyl carrier protein-like)|interpro:IPR011032(GroES-like)|interpro:IPR013149(Alcohol dehydrogenase, zinc-binding)|interpro:IPR013217(Methyltransferase type 12)|interpro:IPR013968(Polyketide synthase, KR)|interpro:IPR014030(Beta-ketoacyl synthase, N-terminal)|interpro:IPR014031(Beta-ketoacyl synthase, C-terminal)|interpro:IPR014043(Acyl transferase)|interpro:IPR016035(Acyl transferase/acyl hydrolase/lysophospholipase)|interpro:IPR016036(Malonyl-CoA ACP transacylase, ACP-binding)|interpro:IPR016039(Thiolase-like)|interpro:IPR018201|interpro:IPR020806|interpro:IPR020807|interpro:IPR020841|interpro:IPR020843|interpro:IPR029058|interpro:IPR029063|interpro:IPR032821|interpro:IPR036291|interpro:IPR036736|interpro:IPR042104|mint:P49327|rcsb pdb:1XKT|rcsb pdb:2CG5|rcsb pdb:2JFD|rcsb pdb:2JFK|rcsb pdb:2PX6|rcsb pdb:3HHD|rcsb pdb:3TJM|rcsb pdb:4PIV|rcsb pdb:4W82|rcsb pdb:4W9N|rcsb pdb:4Z49|rcsb pdb:5C37|rcsb pdb:6NNA|reactome:R-HSA-163765|reactome:R-HSA-199220|reactome:R-HSA-2426168|reactome:R-HSA-75105|reactome:R-HSA-9029558|go:"GO:0047117"("enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) activity")|refseq:XP_011521840.1|dip:DIP-33681N	ensembl:ENST00000325686(transcript)|ensembl:ENST00000441843(transcript)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0004000"(adenosine deaminase activity)|go:"GO:0004731"(purine-nucleoside phosphorylase activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006954"(inflammatory response)|go:"GO:0017061"(S-methyl-5-thioadenosine phosphorylase activity)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0045087"(innate immune response)|go:"GO:0047975"(guanosine phosphorylase activity)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:1900542"(regulation of purine nucleotide metabolic process)|interpro:IPR003730(Protein of unknown function DUF152)|interpro:IPR011324(Cytotoxic necrotizing factor-like, catalytic)|interpro:IPR038371|ensembl:ENSG00000179630(gene)|refseq:NP_001121775.1|refseq:NP_694950.2|refseq:XP_005266318.1|refseq:XP_006719829.1|refseq:XP_011533235.1|refseq:XP_011533236.1|refseq:XP_016875883.1	-	-	-	figure legend:1C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2016/08/08	2016/08/17	rogid:bQYEH/uQ6l+SPzLBDNCV5yP+yzs9606	rogid:Y/gCMNfRuvW/8zUT3Fvq2ZR9I8o9606	rigid:F5JjMPGS+lhJyb9Agi2Y486oee4	false	-	variant:254-254|mutation with no effect:254-254	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P28288	uniprotkb:Q8IV20	intact:EBI-80992|ensembl:ENSP00000359233|uniprotkb:Q15271|uniprotkb:Q9H529|uniprotkb:Q6NUN5|uniprotkb:Q96DA3|uniprotkb:D3DT46	intact:EBI-12508070|ensembl:ENSP00000391747|ensembl:ENSP00000317619|uniprotkb:A2A3Z6|uniprotkb:Q8N8X5	psi-mi:abcd3_human(display_long)|uniprotkb:ABCD3(gene name)|psi-mi:ABCD3(display_short)|uniprotkb:PMP70(gene name synonym)|uniprotkb:PXMP1(gene name synonym)|uniprotkb:70 kDa peroxisomal membrane protein(gene name synonym)	psi-mi:lacc1_human(display_long)|uniprotkb:LACC1(gene name)|psi-mi:LACC1(display_short)|uniprotkb:C13orf31(gene name synonym)|uniprotkb:FAMIN(gene name synonym)|uniprotkb:Fatty acid metabolism-immunity nexus(gene name synonym)|uniprotkb:Adenosine deaminase LACC1(gene name synonym)|uniprotkb:Guanosine phosphorylase LACC1(gene name synonym)|uniprotkb:Laccase domain-containing protein 1(gene name synonym)|uniprotkb:S-methyl-5'-thioadenosine phosphorylase LACC1(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Cader et al. (2016)	pubmed:27478939|imex:IM-26127	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12508499|imex:IM-26127-25	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000117528(gene)|ensembl:ENST00000370214(transcript)|go:"GO:0005324"(long-chain fatty acid transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0007031"(peroxisome organization)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0015910"(long-chain fatty acid import into peroxisome)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0042493"|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|refseq:NP_001116146.1|refseq:NP_002849.1|go:"GO:0042760"(very long-chain fatty acid catabolic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043621"(protein self-association)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR005283(Peroxysomal long chain fatty acyl transporter)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR017871|interpro:IPR027417|interpro:IPR036640|mint:P28288|reactome:R-HSA-1369062|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9603798	ensembl:ENST00000325686(transcript)|ensembl:ENST00000441843(transcript)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0004000"(adenosine deaminase activity)|go:"GO:0004731"(purine-nucleoside phosphorylase activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006954"(inflammatory response)|go:"GO:0017061"(S-methyl-5-thioadenosine phosphorylase activity)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0045087"(innate immune response)|go:"GO:0047975"(guanosine phosphorylase activity)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:1900542"(regulation of purine nucleotide metabolic process)|interpro:IPR003730(Protein of unknown function DUF152)|interpro:IPR011324(Cytotoxic necrotizing factor-like, catalytic)|interpro:IPR038371|ensembl:ENSG00000179630(gene)|refseq:NP_001121775.1|refseq:NP_694950.2|refseq:XP_005266318.1|refseq:XP_006719829.1|refseq:XP_011533235.1|refseq:XP_011533236.1|refseq:XP_016875883.1	go:"GO:0005777"(peroxisome)	-	-	figure legend:1D,  Supp fig 2A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-macrophage)|taxid:9606(Human macrophages)	-	2016/08/08	2016/08/18	rogid:aUTR1BDihIx1JxtsC5V4vmFAwA49606	rogid:Y/gCMNfRuvW/8zUT3Fvq2ZR9I8o9606	rigid:wrBohZrTSK5+27JLv5ZvuP7J2hI	false	-	-	-	-	psi-mi:"MI:1200"(immunocytochemistry)	psi-mi:"MI:1200"(immunocytochemistry)
uniprotkb:P24270	uniprotkb:P19096	intact:EBI-2924912|uniprotkb:Q3TXQ6|ensembl:ENSMUSP00000028610	intact:EBI-773277|uniprotkb:Q6PB72|uniprotkb:Q8C4Z0|uniprotkb:Q9EQR0|uniprotkb:B1ATU8|ensembl:ENSMUSP00000052872	psi-mi:cata_mouse(display_long)|uniprotkb:Cat(gene name)|psi-mi:Cat(display_short)|uniprotkb:Cas-1(gene name synonym)|uniprotkb:Cas1(gene name synonym)	psi-mi:fas_mouse(display_long)|uniprotkb:Fasn(gene name)|psi-mi:Fasn(display_short)|uniprotkb:Type I Fatty Acid Synthase(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Cader et al. (2016)	pubmed:27478939|imex:IM-26127	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12508562|imex:IM-26127-27	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0055093"(response to hyperoxia)|go:"GO:0070542"(response to fatty acid)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0080184"(response to phenylpropanoid)|interpro:IPR002226(Catalase)|interpro:IPR010582(Catalase-related)|interpro:IPR011614(Catalase, N-terminal)|interpro:IPR018028|interpro:IPR020835|interpro:IPR024708|interpro:IPR024711|interpro:IPR040333|mint:P24270|reactome:R-MMU-3299685|reactome:R-MMU-6798695|reactome:R-MMU-9033241|go:"GO:0051781"(positive regulation of cell division)|ensembl:ENSMUSG00000027187(gene)|ensembl:ENSMUST00000028610(transcript)|go:"GO:0000268"(peroxisome targeting sequence binding)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001822"(kidney development)|go:"GO:0004046"(aminoacylase activity)|go:"GO:0004096"(catalase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005764"(lysosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007568"(aging)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0009060"(aerobic respiration)|go:"GO:0009642"(response to light intensity)|go:"GO:0009650"(UV protection)|go:"GO:0010193"(response to ozone)|go:"GO:0010288"(response to lead ion)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014823"(response to activity)|go:"GO:0014854"(response to inactivity)|go:"GO:0016209"(antioxidant activity)|go:"GO:0016684"(oxidoreductase activity, acting on peroxide as acceptor)|go:"GO:0019899"(enzyme binding)|go:"GO:0020027"(hemoglobin metabolic process)|go:"GO:0020037"(heme binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032355"(response to estradiol)|go:"GO:0032868"(response to insulin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033189"(response to vitamin A)|go:"GO:0033197"(response to vitamin E)|go:"GO:0033591"(response to L-ascorbic acid)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045471"(response to ethanol)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0046872"(metal ion binding)|go:"GO:0050661"(NADP binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|refseq:NP_033934.2	refseq:NP_032014.3|ensembl:ENSMUSG00000025153(gene)|ensembl:ENSMUST00000055655(transcript)|go:"GO:0002068"(glandular epithelial cell development)|go:"GO:0004312"(fatty acid synthase activity)|go:"GO:0004313"([acyl-carrier-protein] S-acetyltransferase activity)|go:"GO:0004314"([acyl-carrier-protein] S-malonyltransferase activity)|go:"GO:0004315"(3-oxoacyl-[acyl-carrier-protein] synthase activity)|go:"GO:0004316"("3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity")|go:"GO:0004317"(3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity)|go:"GO:0004320"(oleoyl-[acyl-carrier-protein] hydrolase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006084"(acetyl-CoA metabolic process)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0008611"(ether lipid biosynthetic process)|go:"GO:0008659"("(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity")|go:"GO:0008693"(3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity)|go:"GO:0009888"(tissue development)|go:"GO:0016295"(myristoyl-[acyl-carrier-protein] hydrolase activity)|go:"GO:0016296"(palmitoyl-[acyl-carrier-protein] hydrolase activity)|go:"GO:0030223"(neutrophil differentiation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0030879"(mammary gland development)|go:"GO:0031177"(phosphopantetheine binding)|go:"GO:0042470"(melanosome)|go:"GO:0042587"(glycogen granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0047117"("enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) activity")|go:"GO:0047451"(3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0090557"(establishment of endothelial intestinal barrier)|go:"GO:0102131"(obsolete 3-oxo-glutaryl-[acp] methyl ester reductase activity)|go:"GO:0102132"(obsolete 3-oxo-pimeloyl-[acp] methyl ester reductase activity)|interpro:IPR001031(Thioesterase)|interpro:IPR001227(Acyl transferase region)|interpro:IPR006162(Phosphopantetheine attachment site)|interpro:IPR009081(Acyl carrier protein-like)|interpro:IPR011032(GroES-like)|interpro:IPR013149(Alcohol dehydrogenase, zinc-binding)|interpro:IPR013217(Methyltransferase type 12)|interpro:IPR013968(Polyketide synthase, KR)|interpro:IPR014030(Beta-ketoacyl synthase, N-terminal)|interpro:IPR014031(Beta-ketoacyl synthase, C-terminal)|interpro:IPR014043(Acyl transferase)|interpro:IPR016035(Acyl transferase/acyl hydrolase/lysophospholipase)|interpro:IPR016036(Malonyl-CoA ACP transacylase, ACP-binding)|interpro:IPR016039(Thiolase-like)|interpro:IPR018201|interpro:IPR020806|interpro:IPR020807|interpro:IPR020841|interpro:IPR020843|interpro:IPR029058|interpro:IPR029063|interpro:IPR032821|interpro:IPR036291|interpro:IPR036736|interpro:IPR042104|mint:P19096|rcsb pdb:5MY0|rcsb pdb:5MY2|rcsb pdb:6ROP|reactome:R-MMU-163765|reactome:R-MMU-199220|reactome:R-MMU-75105	go:"GO:0005777"(peroxisome)	-	-	figure legend:1F|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-bmdm)|taxid:10090(Mus musculus)	-	2016/08/08	2016/08/17	rogid:Ahsw8/VMIQAUw7mWuBSFRn9g/3M10090	rogid:k+MkpzkPX8N0Diy3ovhliRvu73M10090	rigid:7GdpbHXPSWUWG+QQzNOXAnjtyF8	false	-	-	-	-	psi-mi:"MI:1200"(immunocytochemistry)	psi-mi:"MI:1200"(immunocytochemistry)
uniprotkb:P24270	uniprotkb:P19096	intact:EBI-2924912|uniprotkb:Q3TXQ6|ensembl:ENSMUSP00000028610	intact:EBI-773277|uniprotkb:Q6PB72|uniprotkb:Q8C4Z0|uniprotkb:Q9EQR0|uniprotkb:B1ATU8|ensembl:ENSMUSP00000052872	psi-mi:cata_mouse(display_long)|uniprotkb:Cat(gene name)|psi-mi:Cat(display_short)|uniprotkb:Cas-1(gene name synonym)|uniprotkb:Cas1(gene name synonym)	psi-mi:fas_mouse(display_long)|uniprotkb:Fasn(gene name)|psi-mi:Fasn(display_short)|uniprotkb:Type I Fatty Acid Synthase(gene name synonym)	psi-mi:"MI:0813"(proximity ligation assay)	Cader et al. (2016)	pubmed:27478939|imex:IM-26127	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12508575|imex:IM-26127-15	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0055093"(response to hyperoxia)|go:"GO:0070542"(response to fatty acid)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0080184"(response to phenylpropanoid)|interpro:IPR002226(Catalase)|interpro:IPR010582(Catalase-related)|interpro:IPR011614(Catalase, N-terminal)|interpro:IPR018028|interpro:IPR020835|interpro:IPR024708|interpro:IPR024711|interpro:IPR040333|mint:P24270|reactome:R-MMU-3299685|reactome:R-MMU-6798695|reactome:R-MMU-9033241|go:"GO:0051781"(positive regulation of cell division)|ensembl:ENSMUSG00000027187(gene)|ensembl:ENSMUST00000028610(transcript)|go:"GO:0000268"(peroxisome targeting sequence binding)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001822"(kidney development)|go:"GO:0004046"(aminoacylase activity)|go:"GO:0004096"(catalase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005764"(lysosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007568"(aging)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0009060"(aerobic respiration)|go:"GO:0009642"(response to light intensity)|go:"GO:0009650"(UV protection)|go:"GO:0010193"(response to ozone)|go:"GO:0010288"(response to lead ion)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014823"(response to activity)|go:"GO:0014854"(response to inactivity)|go:"GO:0016209"(antioxidant activity)|go:"GO:0016684"(oxidoreductase activity, acting on peroxide as acceptor)|go:"GO:0019899"(enzyme binding)|go:"GO:0020027"(hemoglobin metabolic process)|go:"GO:0020037"(heme binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032355"(response to estradiol)|go:"GO:0032868"(response to insulin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033189"(response to vitamin A)|go:"GO:0033197"(response to vitamin E)|go:"GO:0033591"(response to L-ascorbic acid)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045471"(response to ethanol)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0046872"(metal ion binding)|go:"GO:0050661"(NADP binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|refseq:NP_033934.2	refseq:NP_032014.3|ensembl:ENSMUSG00000025153(gene)|ensembl:ENSMUST00000055655(transcript)|go:"GO:0002068"(glandular epithelial cell development)|go:"GO:0004312"(fatty acid synthase activity)|go:"GO:0004313"([acyl-carrier-protein] S-acetyltransferase activity)|go:"GO:0004314"([acyl-carrier-protein] S-malonyltransferase activity)|go:"GO:0004315"(3-oxoacyl-[acyl-carrier-protein] synthase activity)|go:"GO:0004316"("3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity")|go:"GO:0004317"(3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity)|go:"GO:0004320"(oleoyl-[acyl-carrier-protein] hydrolase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006084"(acetyl-CoA metabolic process)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0008611"(ether lipid biosynthetic process)|go:"GO:0008659"("(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity")|go:"GO:0008693"(3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity)|go:"GO:0009888"(tissue development)|go:"GO:0016295"(myristoyl-[acyl-carrier-protein] hydrolase activity)|go:"GO:0016296"(palmitoyl-[acyl-carrier-protein] hydrolase activity)|go:"GO:0030223"(neutrophil differentiation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0030879"(mammary gland development)|go:"GO:0031177"(phosphopantetheine binding)|go:"GO:0042470"(melanosome)|go:"GO:0042587"(glycogen granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0047117"("enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) activity")|go:"GO:0047451"(3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0090557"(establishment of endothelial intestinal barrier)|go:"GO:0102131"(obsolete 3-oxo-glutaryl-[acp] methyl ester reductase activity)|go:"GO:0102132"(obsolete 3-oxo-pimeloyl-[acp] methyl ester reductase activity)|interpro:IPR001031(Thioesterase)|interpro:IPR001227(Acyl transferase region)|interpro:IPR006162(Phosphopantetheine attachment site)|interpro:IPR009081(Acyl carrier protein-like)|interpro:IPR011032(GroES-like)|interpro:IPR013149(Alcohol dehydrogenase, zinc-binding)|interpro:IPR013217(Methyltransferase type 12)|interpro:IPR013968(Polyketide synthase, KR)|interpro:IPR014030(Beta-ketoacyl synthase, N-terminal)|interpro:IPR014031(Beta-ketoacyl synthase, C-terminal)|interpro:IPR014043(Acyl transferase)|interpro:IPR016035(Acyl transferase/acyl hydrolase/lysophospholipase)|interpro:IPR016036(Malonyl-CoA ACP transacylase, ACP-binding)|interpro:IPR016039(Thiolase-like)|interpro:IPR018201|interpro:IPR020806|interpro:IPR020807|interpro:IPR020841|interpro:IPR020843|interpro:IPR029058|interpro:IPR029063|interpro:IPR032821|interpro:IPR036291|interpro:IPR036736|interpro:IPR042104|mint:P19096|rcsb pdb:5MY0|rcsb pdb:5MY2|rcsb pdb:6ROP|reactome:R-MMU-163765|reactome:R-MMU-199220|reactome:R-MMU-75105	go:"GO:0005777"(peroxisome)	-	-	figure legend:1H|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-bmdm)|taxid:10090(Mus musculus)	-	2016/08/08	2016/08/17	rogid:Ahsw8/VMIQAUw7mWuBSFRn9g/3M10090	rogid:k+MkpzkPX8N0Diy3ovhliRvu73M10090	rigid:7GdpbHXPSWUWG+QQzNOXAnjtyF8	false	-	-	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:P28288	uniprotkb:Q8IV20	intact:EBI-80992|ensembl:ENSP00000359233|uniprotkb:Q15271|uniprotkb:Q9H529|uniprotkb:Q6NUN5|uniprotkb:Q96DA3|uniprotkb:D3DT46	intact:EBI-12508070|ensembl:ENSP00000391747|ensembl:ENSP00000317619|uniprotkb:A2A3Z6|uniprotkb:Q8N8X5	psi-mi:abcd3_human(display_long)|uniprotkb:ABCD3(gene name)|psi-mi:ABCD3(display_short)|uniprotkb:PMP70(gene name synonym)|uniprotkb:PXMP1(gene name synonym)|uniprotkb:70 kDa peroxisomal membrane protein(gene name synonym)	psi-mi:lacc1_human(display_long)|uniprotkb:LACC1(gene name)|psi-mi:LACC1(display_short)|uniprotkb:C13orf31(gene name synonym)|uniprotkb:FAMIN(gene name synonym)|uniprotkb:Fatty acid metabolism-immunity nexus(gene name synonym)|uniprotkb:Adenosine deaminase LACC1(gene name synonym)|uniprotkb:Guanosine phosphorylase LACC1(gene name synonym)|uniprotkb:Laccase domain-containing protein 1(gene name synonym)|uniprotkb:S-methyl-5'-thioadenosine phosphorylase LACC1(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Cader et al. (2016)	pubmed:27478939|imex:IM-26127	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12508863|imex:IM-26127-17	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000117528(gene)|ensembl:ENST00000370214(transcript)|go:"GO:0005324"(long-chain fatty acid transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0007031"(peroxisome organization)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0015910"(long-chain fatty acid import into peroxisome)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0042493"|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|refseq:NP_001116146.1|refseq:NP_002849.1|go:"GO:0042760"(very long-chain fatty acid catabolic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043621"(protein self-association)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR005283(Peroxysomal long chain fatty acyl transporter)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR017871|interpro:IPR027417|interpro:IPR036640|mint:P28288|reactome:R-HSA-1369062|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9603798	ensembl:ENST00000325686(transcript)|ensembl:ENST00000441843(transcript)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0004000"(adenosine deaminase activity)|go:"GO:0004731"(purine-nucleoside phosphorylase activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006954"(inflammatory response)|go:"GO:0017061"(S-methyl-5-thioadenosine phosphorylase activity)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0045087"(innate immune response)|go:"GO:0047975"(guanosine phosphorylase activity)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:1900542"(regulation of purine nucleotide metabolic process)|interpro:IPR003730(Protein of unknown function DUF152)|interpro:IPR011324(Cytotoxic necrotizing factor-like, catalytic)|interpro:IPR038371|ensembl:ENSG00000179630(gene)|refseq:NP_001121775.1|refseq:NP_694950.2|refseq:XP_005266318.1|refseq:XP_006719829.1|refseq:XP_011533235.1|refseq:XP_011533236.1|refseq:XP_016875883.1	go:"GO:0005777"(peroxisome)	-	-	figure legend:Supp fig 2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-thp-1)|taxid:9606(Homo sapiens acute monocytic leukemia cells)	-	2016/08/08	2016/08/18	rogid:aUTR1BDihIx1JxtsC5V4vmFAwA49606	rogid:Y/gCMNfRuvW/8zUT3Fvq2ZR9I8o9606	rigid:wrBohZrTSK5+27JLv5ZvuP7J2hI	false	-	-	-	-	psi-mi:"MI:1200"(immunocytochemistry)	psi-mi:"MI:1200"(immunocytochemistry)
uniprotkb:P04040	uniprotkb:Q8IV20	intact:EBI-2432181|uniprotkb:A8K6C0|uniprotkb:B2RCZ9|uniprotkb:Q9UC85|uniprotkb:Q2M1U4|uniprotkb:Q4VXX5|uniprotkb:Q9BWT9|uniprotkb:D3DR07|ensembl:ENSP00000241052	intact:EBI-12508070|ensembl:ENSP00000391747|ensembl:ENSP00000317619|uniprotkb:A2A3Z6|uniprotkb:Q8N8X5	psi-mi:cata_human(display_long)|uniprotkb:CAT(gene name)|psi-mi:CAT(display_short)	psi-mi:lacc1_human(display_long)|uniprotkb:LACC1(gene name)|psi-mi:LACC1(display_short)|uniprotkb:C13orf31(gene name synonym)|uniprotkb:FAMIN(gene name synonym)|uniprotkb:Fatty acid metabolism-immunity nexus(gene name synonym)|uniprotkb:Adenosine deaminase LACC1(gene name synonym)|uniprotkb:Guanosine phosphorylase LACC1(gene name synonym)|uniprotkb:Laccase domain-containing protein 1(gene name synonym)|uniprotkb:S-methyl-5'-thioadenosine phosphorylase LACC1(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Cader et al. (2016)	pubmed:27478939|imex:IM-26127	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12508876|imex:IM-26127-29	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001743.1|ensembl:ENSG00000121691(gene)|ensembl:ENST00000241052(transcript)|go:"GO:0000268"(peroxisome targeting sequence binding)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001666"(response to hypoxia)|go:"GO:0004046"(aminoacylase activity)|go:"GO:0004096"(catalase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005764"(lysosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0007568"(aging)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0009060"(aerobic respiration)|go:"GO:0009642"(response to light intensity)|go:"GO:0009650"(UV protection)|go:"GO:0010193"(response to ozone)|go:"GO:0010288"(response to lead ion)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014823"(response to activity)|go:"GO:0014854"(response to inactivity)|go:"GO:0016020"(membrane)|go:"GO:0016209"(antioxidant activity)|go:"GO:0016684"(oxidoreductase activity, acting on peroxide as acceptor)|go:"GO:0019899"(enzyme binding)|go:"GO:0020027"(hemoglobin metabolic process)|go:"GO:0020037"(heme binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032355"(response to estradiol)|go:"GO:0032868"(response to insulin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033189"(response to vitamin A)|go:"GO:0033197"(response to vitamin E)|go:"GO:0033591"(response to L-ascorbic acid)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045471"(response to ethanol)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0046872"(metal ion binding)|go:"GO:0050661"(NADP binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070542"(response to fatty acid)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0080184"(response to phenylpropanoid)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR002226(Catalase)|interpro:IPR010582(Catalase-related)|interpro:IPR011614(Catalase, N-terminal)|interpro:IPR018028|interpro:IPR020835|interpro:IPR024708|interpro:IPR024711|interpro:IPR040333|mint:P04040|rcsb pdb:1DGB|rcsb pdb:1DGF|rcsb pdb:1DGG|rcsb pdb:1DGH|rcsb pdb:1F4J|rcsb pdb:1QQW|reactome:R-HSA-3299685|reactome:R-HSA-6798695|reactome:R-HSA-9033241|reactome:R-HSA-9615017	ensembl:ENST00000325686(transcript)|ensembl:ENST00000441843(transcript)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0004000"(adenosine deaminase activity)|go:"GO:0004731"(purine-nucleoside phosphorylase activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006954"(inflammatory response)|go:"GO:0017061"(S-methyl-5-thioadenosine phosphorylase activity)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0045087"(innate immune response)|go:"GO:0047975"(guanosine phosphorylase activity)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:1900542"(regulation of purine nucleotide metabolic process)|interpro:IPR003730(Protein of unknown function DUF152)|interpro:IPR011324(Cytotoxic necrotizing factor-like, catalytic)|interpro:IPR038371|ensembl:ENSG00000179630(gene)|refseq:NP_001121775.1|refseq:NP_694950.2|refseq:XP_005266318.1|refseq:XP_006719829.1|refseq:XP_011533235.1|refseq:XP_011533236.1|refseq:XP_016875883.1	go:"GO:0005777"(peroxisome)	-	-	figure legend:Supp fig 2C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-thp-1)|taxid:9606(Homo sapiens acute monocytic leukemia cells)	-	2016/08/08	2016/08/18	rogid:IWdPQIuCq9vCj8I0HmshkJwAAqg9606	rogid:Y/gCMNfRuvW/8zUT3Fvq2ZR9I8o9606	rigid:ILWA2/n0BZ4cmvi1h/RTV0JMOZo	false	-	-	-	-	psi-mi:"MI:1200"(immunocytochemistry)	psi-mi:"MI:1200"(immunocytochemistry)