#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q68871	uniprotkb:Q764M6	intact:EBI-12522528	intact:EBI-12512266|ensembl:ENSSSCP00040008173	psi-mi:q68871_9flav(display_long)|uniprotkb:Capsid protein C(gene name synonym)|uniprotkb:Cysteine protease NS2(gene name synonym)|uniprotkb:"E(rns) glycoprotein"(gene name synonym)|uniprotkb:Envelope glycoprotein E1(gene name synonym)|uniprotkb:Envelope glycoprotein E2(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:N-terminal protease(gene name synonym)|uniprotkb:NS5B(gene name synonym)|uniprotkb:Non-structural protein 2(gene name synonym)|uniprotkb:Non-structural protein 2-3(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Non-structural protein 5A(gene name synonym)|uniprotkb:RNA-directed RNA polymerase(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:gp33(gene name synonym)|uniprotkb:gp44/48(gene name synonym)|uniprotkb:gp55(gene name synonym)|uniprotkb:Viroporin p7(gene name synonym)	psi-mi:irf3_pig(display_long)|uniprotkb:IRF3(gene name)|psi-mi:IRF3(display_short)	psi-mi:"MI:0404"(comigration in non denaturing gel electrophoresis)	Gottipati et al. (2016)	pubmed:27334592|imex:IM-26098	taxid:358769(classical swine fever virus - alfort/187)|taxid:358769(classical swine fever virus - alfort/187)	taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-12594842|imex:IM-26098-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033897"(ribonuclease T2 activity)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044228"(host cell surface)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0070008"(serine-type exopeptidase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000280(Peptidase S31, pestivurus polyprotein NS3/p80)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR008751(Peptidase C53, pestivirus Npro)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR021824|interpro:IPR022120|interpro:IPR027417|interpro:IPR030399|interpro:IPR032521|interpro:IPR033130|rcsb pdb:4H9J|rcsb pdb:4H9K|interpro:IPR042309|interpro:IPR042310|interpro:IPR042311|interpro:IPR036430|interpro:IPR042542|interpro:IPR043502|interpro:IPR043128	ensembl:ENSSSCG00040014662(gene)|ensembl:ENSSSCT00040019663(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035666"(TRIF-dependent toll-like receptor signaling pathway)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|go:"GO:0098586"(cellular response to virus)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|reactome:R-SSC-1169408|reactome:R-SSC-1606341|reactome:R-SSC-168928|reactome:R-SSC-3134973|reactome:R-SSC-3134975|reactome:R-SSC-3270619|reactome:R-SSC-9013973|reactome:R-SSC-918233|reactome:R-SSC-933541|reactome:R-SSC-936440|reactome:R-SSC-936964|refseq:NP_998935.1	-	-	-	figure legend:1B, 2A|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/10/27	2016/11/07	rogid:Q5SceFsLg7z7DSoVZnGCx+9+kAI358769	rogid:k8mIgjpiImgr8GDDQbkAz1SlbfI9823	rigid:qT0WPVZ4a2LQXnI0SMfRILNxc7I	false	-	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:F1RK46	uniprotkb:Q764M6	intact:EBI-12595681|ensembl:ENSSSCP00000008490	intact:EBI-12512266|ensembl:ENSSSCP00040008173	psi-mi:f1rk46_pig(display_long)|uniprotkb:CREBBP(gene name)|psi-mi:CREBBP(display_short)	psi-mi:irf3_pig(display_long)|uniprotkb:IRF3(gene name)|psi-mi:IRF3(display_short)	psi-mi:"MI:0404"(comigration in non denaturing gel electrophoresis)	Gottipati et al. (2016)	pubmed:27334592|imex:IM-26098	taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)")	taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-12595673|imex:IM-26098-21	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSSSCG00000007951(gene)|ensembl:ENSSSCT00000008714(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000785"(chromatin)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0002039"(p53 binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0018076"(N-terminal peptidyl-lysine acetylation)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0043426"(MRF binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048511"(rhythmic process)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1990258"(histone glutamine methylation)|interpro:IPR000197(Zinc finger, TAZ-type)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001487(Bromodomain)|interpro:IPR003101(Coactivator CBP, KIX)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010303(Protein of unknown function DUF902, CREBbp)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013178(H3K56 histone acetylation protein, RTT109)|interpro:IPR014744(Nuclear receptor coactivator, CREB-bp-like, interlocking)|interpro:IPR018359|interpro:IPR031162|interpro:IPR035898|interpro:IPR036427|interpro:IPR036529|interpro:IPR037073|interpro:IPR038547|interpro:IPR043145|reactome:R-SSC-1234158|reactome:R-SSC-201722|reactome:R-SSC-3134973|reactome:R-SSC-3371568|reactome:R-SSC-350054|reactome:R-SSC-5621575|reactome:R-SSC-8866907|reactome:R-SSC-8939246|reactome:R-SSC-8941856|reactome:R-SSC-918233|reactome:R-SSC-933541|reactome:R-SSC-9617629	ensembl:ENSSSCG00040014662(gene)|ensembl:ENSSSCT00040019663(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035666"(TRIF-dependent toll-like receptor signaling pathway)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|go:"GO:0098586"(cellular response to virus)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|reactome:R-SSC-1169408|reactome:R-SSC-1606341|reactome:R-SSC-168928|reactome:R-SSC-3134973|reactome:R-SSC-3134975|reactome:R-SSC-3270619|reactome:R-SSC-9013973|reactome:R-SSC-918233|reactome:R-SSC-933541|reactome:R-SSC-936440|reactome:R-SSC-936964|refseq:NP_998935.1	-	-	-	figure legend:3A|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/10/27	2017/12/04	rogid:9GdZtm0iq8h/k02WhMYzCL7KKlQ9823	rogid:k8mIgjpiImgr8GDDQbkAz1SlbfI9823	rigid:3dwXxB/Nm6txFGWpSMl+vbwRWgo	false	mutation:2060-2061|binding-associated region:2061-2107	mutation:396-396,394-394,400-400,402-402,403-403	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:F1RK46	uniprotkb:Q68871	intact:EBI-12595681|ensembl:ENSSSCP00000008490	intact:EBI-12522528	psi-mi:f1rk46_pig(display_long)|uniprotkb:CREBBP(gene name)|psi-mi:CREBBP(display_short)	psi-mi:q68871_9flav(display_long)|uniprotkb:Capsid protein C(gene name synonym)|uniprotkb:Cysteine protease NS2(gene name synonym)|uniprotkb:"E(rns) glycoprotein"(gene name synonym)|uniprotkb:Envelope glycoprotein E1(gene name synonym)|uniprotkb:Envelope glycoprotein E2(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:N-terminal protease(gene name synonym)|uniprotkb:NS5B(gene name synonym)|uniprotkb:Non-structural protein 2(gene name synonym)|uniprotkb:Non-structural protein 2-3(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Non-structural protein 5A(gene name synonym)|uniprotkb:RNA-directed RNA polymerase(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:gp33(gene name synonym)|uniprotkb:gp44/48(gene name synonym)|uniprotkb:gp55(gene name synonym)|uniprotkb:Viroporin p7(gene name synonym)	psi-mi:"MI:0404"(comigration in non denaturing gel electrophoresis)	Gottipati et al. (2016)	pubmed:27334592|imex:IM-26098	taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)")	taxid:358769(classical swine fever virus - alfort/187)|taxid:358769(classical swine fever virus - alfort/187)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-12595673|imex:IM-26098-21	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSSSCG00000007951(gene)|ensembl:ENSSSCT00000008714(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000785"(chromatin)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0002039"(p53 binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0018076"(N-terminal peptidyl-lysine acetylation)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0043426"(MRF binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048511"(rhythmic process)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1990258"(histone glutamine methylation)|interpro:IPR000197(Zinc finger, TAZ-type)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001487(Bromodomain)|interpro:IPR003101(Coactivator CBP, KIX)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010303(Protein of unknown function DUF902, CREBbp)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013178(H3K56 histone acetylation protein, RTT109)|interpro:IPR014744(Nuclear receptor coactivator, CREB-bp-like, interlocking)|interpro:IPR018359|interpro:IPR031162|interpro:IPR035898|interpro:IPR036427|interpro:IPR036529|interpro:IPR037073|interpro:IPR038547|interpro:IPR043145|reactome:R-SSC-1234158|reactome:R-SSC-201722|reactome:R-SSC-3134973|reactome:R-SSC-3371568|reactome:R-SSC-350054|reactome:R-SSC-5621575|reactome:R-SSC-8866907|reactome:R-SSC-8939246|reactome:R-SSC-8941856|reactome:R-SSC-918233|reactome:R-SSC-933541|reactome:R-SSC-9617629	go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033897"(ribonuclease T2 activity)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044228"(host cell surface)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0070008"(serine-type exopeptidase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000280(Peptidase S31, pestivurus polyprotein NS3/p80)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR008751(Peptidase C53, pestivirus Npro)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR021824|interpro:IPR022120|interpro:IPR027417|interpro:IPR030399|interpro:IPR032521|interpro:IPR033130|rcsb pdb:4H9J|rcsb pdb:4H9K|interpro:IPR042309|interpro:IPR042310|interpro:IPR042311|interpro:IPR036430|interpro:IPR042542|interpro:IPR043502|interpro:IPR043128	-	-	-	figure legend:3A|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/10/27	2017/12/04	rogid:9GdZtm0iq8h/k02WhMYzCL7KKlQ9823	rogid:Q5SceFsLg7z7DSoVZnGCx+9+kAI358769	rigid:3dwXxB/Nm6txFGWpSMl+vbwRWgo	false	mutation:2060-2061|binding-associated region:2061-2107	binding-associated region:1..1-168..168	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:F1RK46	uniprotkb:Q764M6	intact:EBI-12595681|ensembl:ENSSSCP00000008490	intact:EBI-12512266|ensembl:ENSSSCP00040008173	psi-mi:f1rk46_pig(display_long)|uniprotkb:CREBBP(gene name)|psi-mi:CREBBP(display_short)	psi-mi:irf3_pig(display_long)|uniprotkb:IRF3(gene name)|psi-mi:IRF3(display_short)	psi-mi:"MI:0404"(comigration in non denaturing gel electrophoresis)	Gottipati et al. (2016)	pubmed:27334592|imex:IM-26098	taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)")	taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-12595732|imex:IM-26098-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSSSCG00000007951(gene)|ensembl:ENSSSCT00000008714(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000785"(chromatin)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0002039"(p53 binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0018076"(N-terminal peptidyl-lysine acetylation)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0043426"(MRF binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048511"(rhythmic process)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1990258"(histone glutamine methylation)|interpro:IPR000197(Zinc finger, TAZ-type)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001487(Bromodomain)|interpro:IPR003101(Coactivator CBP, KIX)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010303(Protein of unknown function DUF902, CREBbp)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013178(H3K56 histone acetylation protein, RTT109)|interpro:IPR014744(Nuclear receptor coactivator, CREB-bp-like, interlocking)|interpro:IPR018359|interpro:IPR031162|interpro:IPR035898|interpro:IPR036427|interpro:IPR036529|interpro:IPR037073|interpro:IPR038547|interpro:IPR043145|reactome:R-SSC-1234158|reactome:R-SSC-201722|reactome:R-SSC-3134973|reactome:R-SSC-3371568|reactome:R-SSC-350054|reactome:R-SSC-5621575|reactome:R-SSC-8866907|reactome:R-SSC-8939246|reactome:R-SSC-8941856|reactome:R-SSC-918233|reactome:R-SSC-933541|reactome:R-SSC-9617629	ensembl:ENSSSCG00040014662(gene)|ensembl:ENSSSCT00040019663(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035666"(TRIF-dependent toll-like receptor signaling pathway)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|go:"GO:0098586"(cellular response to virus)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|reactome:R-SSC-1169408|reactome:R-SSC-1606341|reactome:R-SSC-168928|reactome:R-SSC-3134973|reactome:R-SSC-3134975|reactome:R-SSC-3270619|reactome:R-SSC-9013973|reactome:R-SSC-918233|reactome:R-SSC-933541|reactome:R-SSC-936440|reactome:R-SSC-936964|refseq:NP_998935.1	-	-	-	figure legend:3A|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/10/27	2017/12/04	rogid:9GdZtm0iq8h/k02WhMYzCL7KKlQ9823	rogid:k8mIgjpiImgr8GDDQbkAz1SlbfI9823	rigid:3dwXxB/Nm6txFGWpSMl+vbwRWgo	false	mutation:2060-2061|binding-associated region:2061-2107	mutation:396-396,394-394,400-400,402-402,403-403	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:F1RK46	uniprotkb:Q68871	intact:EBI-12595681|ensembl:ENSSSCP00000008490	intact:EBI-12522528	psi-mi:f1rk46_pig(display_long)|uniprotkb:CREBBP(gene name)|psi-mi:CREBBP(display_short)	psi-mi:q68871_9flav(display_long)|uniprotkb:Capsid protein C(gene name synonym)|uniprotkb:Cysteine protease NS2(gene name synonym)|uniprotkb:"E(rns) glycoprotein"(gene name synonym)|uniprotkb:Envelope glycoprotein E1(gene name synonym)|uniprotkb:Envelope glycoprotein E2(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:N-terminal protease(gene name synonym)|uniprotkb:NS5B(gene name synonym)|uniprotkb:Non-structural protein 2(gene name synonym)|uniprotkb:Non-structural protein 2-3(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Non-structural protein 5A(gene name synonym)|uniprotkb:RNA-directed RNA polymerase(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:gp33(gene name synonym)|uniprotkb:gp44/48(gene name synonym)|uniprotkb:gp55(gene name synonym)|uniprotkb:Viroporin p7(gene name synonym)	psi-mi:"MI:0404"(comigration in non denaturing gel electrophoresis)	Gottipati et al. (2016)	pubmed:27334592|imex:IM-26098	taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)")	taxid:358769(classical swine fever virus - alfort/187)|taxid:358769(classical swine fever virus - alfort/187)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-12595732|imex:IM-26098-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSSSCG00000007951(gene)|ensembl:ENSSSCT00000008714(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000785"(chromatin)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0002039"(p53 binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0018076"(N-terminal peptidyl-lysine acetylation)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0043426"(MRF binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048511"(rhythmic process)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1990258"(histone glutamine methylation)|interpro:IPR000197(Zinc finger, TAZ-type)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001487(Bromodomain)|interpro:IPR003101(Coactivator CBP, KIX)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010303(Protein of unknown function DUF902, CREBbp)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013178(H3K56 histone acetylation protein, RTT109)|interpro:IPR014744(Nuclear receptor coactivator, CREB-bp-like, interlocking)|interpro:IPR018359|interpro:IPR031162|interpro:IPR035898|interpro:IPR036427|interpro:IPR036529|interpro:IPR037073|interpro:IPR038547|interpro:IPR043145|reactome:R-SSC-1234158|reactome:R-SSC-201722|reactome:R-SSC-3134973|reactome:R-SSC-3371568|reactome:R-SSC-350054|reactome:R-SSC-5621575|reactome:R-SSC-8866907|reactome:R-SSC-8939246|reactome:R-SSC-8941856|reactome:R-SSC-918233|reactome:R-SSC-933541|reactome:R-SSC-9617629	go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033897"(ribonuclease T2 activity)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044228"(host cell surface)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0070008"(serine-type exopeptidase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000280(Peptidase S31, pestivurus polyprotein NS3/p80)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR008751(Peptidase C53, pestivirus Npro)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR021824|interpro:IPR022120|interpro:IPR027417|interpro:IPR030399|interpro:IPR032521|interpro:IPR033130|rcsb pdb:4H9J|rcsb pdb:4H9K|interpro:IPR042309|interpro:IPR042310|interpro:IPR042311|interpro:IPR036430|interpro:IPR042542|interpro:IPR043502|interpro:IPR043128	-	-	-	figure legend:3A|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/10/27	2017/12/04	rogid:9GdZtm0iq8h/k02WhMYzCL7KKlQ9823	rogid:Q5SceFsLg7z7DSoVZnGCx+9+kAI358769	rigid:3dwXxB/Nm6txFGWpSMl+vbwRWgo	false	mutation:2060-2061|binding-associated region:2061-2107	binding-associated region:1..1-168..168	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:F1RK46	uniprotkb:Q764M6	intact:EBI-12595681|ensembl:ENSSSCP00000008490	intact:EBI-12512266|ensembl:ENSSSCP00040008173	psi-mi:f1rk46_pig(display_long)|uniprotkb:CREBBP(gene name)|psi-mi:CREBBP(display_short)	psi-mi:irf3_pig(display_long)|uniprotkb:IRF3(gene name)|psi-mi:IRF3(display_short)	psi-mi:"MI:0404"(comigration in non denaturing gel electrophoresis)	Gottipati et al. (2016)	pubmed:27334592|imex:IM-26098	taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)")	taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-12595757|imex:IM-26098-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSSSCG00000007951(gene)|ensembl:ENSSSCT00000008714(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000785"(chromatin)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0002039"(p53 binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0018076"(N-terminal peptidyl-lysine acetylation)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0043426"(MRF binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048511"(rhythmic process)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1990258"(histone glutamine methylation)|interpro:IPR000197(Zinc finger, TAZ-type)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001487(Bromodomain)|interpro:IPR003101(Coactivator CBP, KIX)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010303(Protein of unknown function DUF902, CREBbp)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013178(H3K56 histone acetylation protein, RTT109)|interpro:IPR014744(Nuclear receptor coactivator, CREB-bp-like, interlocking)|interpro:IPR018359|interpro:IPR031162|interpro:IPR035898|interpro:IPR036427|interpro:IPR036529|interpro:IPR037073|interpro:IPR038547|interpro:IPR043145|reactome:R-SSC-1234158|reactome:R-SSC-201722|reactome:R-SSC-3134973|reactome:R-SSC-3371568|reactome:R-SSC-350054|reactome:R-SSC-5621575|reactome:R-SSC-8866907|reactome:R-SSC-8939246|reactome:R-SSC-8941856|reactome:R-SSC-918233|reactome:R-SSC-933541|reactome:R-SSC-9617629	ensembl:ENSSSCG00040014662(gene)|ensembl:ENSSSCT00040019663(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035666"(TRIF-dependent toll-like receptor signaling pathway)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|go:"GO:0098586"(cellular response to virus)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|reactome:R-SSC-1169408|reactome:R-SSC-1606341|reactome:R-SSC-168928|reactome:R-SSC-3134973|reactome:R-SSC-3134975|reactome:R-SSC-3270619|reactome:R-SSC-9013973|reactome:R-SSC-918233|reactome:R-SSC-933541|reactome:R-SSC-936440|reactome:R-SSC-936964|refseq:NP_998935.1	-	-	-	figure legend:3A|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/10/27	2017/12/04	rogid:9GdZtm0iq8h/k02WhMYzCL7KKlQ9823	rogid:k8mIgjpiImgr8GDDQbkAz1SlbfI9823	rigid:n+hBFVVeOnJwglNvDngYRRRs/eQ	false	binding-associated region:2061-2107|mutation:2060-2061	mutation:396-396,394-394,400-400,402-402,403-403	2	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q764M6	uniprotkb:F1RK46	intact:EBI-12512266|ensembl:ENSSSCP00040008173	intact:EBI-12595681|ensembl:ENSSSCP00000008490	psi-mi:irf3_pig(display_long)|uniprotkb:IRF3(gene name)|psi-mi:IRF3(display_short)	psi-mi:f1rk46_pig(display_long)|uniprotkb:CREBBP(gene name)|psi-mi:CREBBP(display_short)	psi-mi:"MI:0404"(comigration in non denaturing gel electrophoresis)	Gottipati et al. (2016)	pubmed:27334592|imex:IM-26098	taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)")	taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-12595779|imex:IM-26098-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSSSCG00040014662(gene)|ensembl:ENSSSCT00040019663(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035666"(TRIF-dependent toll-like receptor signaling pathway)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|go:"GO:0098586"(cellular response to virus)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|reactome:R-SSC-1169408|reactome:R-SSC-1606341|reactome:R-SSC-168928|reactome:R-SSC-3134973|reactome:R-SSC-3134975|reactome:R-SSC-3270619|reactome:R-SSC-9013973|reactome:R-SSC-918233|reactome:R-SSC-933541|reactome:R-SSC-936440|reactome:R-SSC-936964|refseq:NP_998935.1	ensembl:ENSSSCG00000007951(gene)|ensembl:ENSSSCT00000008714(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000785"(chromatin)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0002039"(p53 binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0018076"(N-terminal peptidyl-lysine acetylation)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0043426"(MRF binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048511"(rhythmic process)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1990258"(histone glutamine methylation)|interpro:IPR000197(Zinc finger, TAZ-type)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001487(Bromodomain)|interpro:IPR003101(Coactivator CBP, KIX)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010303(Protein of unknown function DUF902, CREBbp)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013178(H3K56 histone acetylation protein, RTT109)|interpro:IPR014744(Nuclear receptor coactivator, CREB-bp-like, interlocking)|interpro:IPR018359|interpro:IPR031162|interpro:IPR035898|interpro:IPR036427|interpro:IPR036529|interpro:IPR037073|interpro:IPR038547|interpro:IPR043145|reactome:R-SSC-1234158|reactome:R-SSC-201722|reactome:R-SSC-3134973|reactome:R-SSC-3371568|reactome:R-SSC-350054|reactome:R-SSC-5621575|reactome:R-SSC-8866907|reactome:R-SSC-8939246|reactome:R-SSC-8941856|reactome:R-SSC-918233|reactome:R-SSC-933541|reactome:R-SSC-9617629	-	-	-	figure legend:3A|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/10/27	2017/12/04	rogid:k8mIgjpiImgr8GDDQbkAz1SlbfI9823	rogid:9GdZtm0iq8h/k02WhMYzCL7KKlQ9823	rigid:n+hBFVVeOnJwglNvDngYRRRs/eQ	false	mutation:396-396,394-394,400-400,402-402,403-403	mutation:2060-2061|binding-associated region:2061-2107	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:F1RK46	uniprotkb:Q764M6	intact:EBI-12595681|ensembl:ENSSSCP00000008490	intact:EBI-12512266|ensembl:ENSSSCP00040008173	psi-mi:f1rk46_pig(display_long)|uniprotkb:CREBBP(gene name)|psi-mi:CREBBP(display_short)	psi-mi:irf3_pig(display_long)|uniprotkb:IRF3(gene name)|psi-mi:IRF3(display_short)	psi-mi:"MI:0404"(comigration in non denaturing gel electrophoresis)	Gottipati et al. (2016)	pubmed:27334592|imex:IM-26098	taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)")	taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-12595845|imex:IM-26098-19	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSSSCG00000007951(gene)|ensembl:ENSSSCT00000008714(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000785"(chromatin)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0002039"(p53 binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0018076"(N-terminal peptidyl-lysine acetylation)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0043426"(MRF binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048511"(rhythmic process)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1990258"(histone glutamine methylation)|interpro:IPR000197(Zinc finger, TAZ-type)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001487(Bromodomain)|interpro:IPR003101(Coactivator CBP, KIX)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010303(Protein of unknown function DUF902, CREBbp)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013178(H3K56 histone acetylation protein, RTT109)|interpro:IPR014744(Nuclear receptor coactivator, CREB-bp-like, interlocking)|interpro:IPR018359|interpro:IPR031162|interpro:IPR035898|interpro:IPR036427|interpro:IPR036529|interpro:IPR037073|interpro:IPR038547|interpro:IPR043145|reactome:R-SSC-1234158|reactome:R-SSC-201722|reactome:R-SSC-3134973|reactome:R-SSC-3371568|reactome:R-SSC-350054|reactome:R-SSC-5621575|reactome:R-SSC-8866907|reactome:R-SSC-8939246|reactome:R-SSC-8941856|reactome:R-SSC-918233|reactome:R-SSC-933541|reactome:R-SSC-9617629	ensembl:ENSSSCG00040014662(gene)|ensembl:ENSSSCT00040019663(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035666"(TRIF-dependent toll-like receptor signaling pathway)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|go:"GO:0098586"(cellular response to virus)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|reactome:R-SSC-1169408|reactome:R-SSC-1606341|reactome:R-SSC-168928|reactome:R-SSC-3134973|reactome:R-SSC-3134975|reactome:R-SSC-3270619|reactome:R-SSC-9013973|reactome:R-SSC-918233|reactome:R-SSC-933541|reactome:R-SSC-936440|reactome:R-SSC-936964|refseq:NP_998935.1	-	-	-	figure legend:4A|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/10/27	2017/12/04	rogid:9GdZtm0iq8h/k02WhMYzCL7KKlQ9823	rogid:k8mIgjpiImgr8GDDQbkAz1SlbfI9823	rigid:3dwXxB/Nm6txFGWpSMl+vbwRWgo	false	mutation:2060-2061|binding-associated region:2061-2107	sufficient binding region:392-419	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:F1RK46	uniprotkb:Q68871	intact:EBI-12595681|ensembl:ENSSSCP00000008490	intact:EBI-12522528	psi-mi:f1rk46_pig(display_long)|uniprotkb:CREBBP(gene name)|psi-mi:CREBBP(display_short)	psi-mi:q68871_9flav(display_long)|uniprotkb:Capsid protein C(gene name synonym)|uniprotkb:Cysteine protease NS2(gene name synonym)|uniprotkb:"E(rns) glycoprotein"(gene name synonym)|uniprotkb:Envelope glycoprotein E1(gene name synonym)|uniprotkb:Envelope glycoprotein E2(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:N-terminal protease(gene name synonym)|uniprotkb:NS5B(gene name synonym)|uniprotkb:Non-structural protein 2(gene name synonym)|uniprotkb:Non-structural protein 2-3(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Non-structural protein 5A(gene name synonym)|uniprotkb:RNA-directed RNA polymerase(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:gp33(gene name synonym)|uniprotkb:gp44/48(gene name synonym)|uniprotkb:gp55(gene name synonym)|uniprotkb:Viroporin p7(gene name synonym)	psi-mi:"MI:0404"(comigration in non denaturing gel electrophoresis)	Gottipati et al. (2016)	pubmed:27334592|imex:IM-26098	taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)")	taxid:358769(classical swine fever virus - alfort/187)|taxid:358769(classical swine fever virus - alfort/187)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-12595845|imex:IM-26098-19	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSSSCG00000007951(gene)|ensembl:ENSSSCT00000008714(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000785"(chromatin)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0002039"(p53 binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0018076"(N-terminal peptidyl-lysine acetylation)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0043426"(MRF binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048511"(rhythmic process)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1990258"(histone glutamine methylation)|interpro:IPR000197(Zinc finger, TAZ-type)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001487(Bromodomain)|interpro:IPR003101(Coactivator CBP, KIX)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010303(Protein of unknown function DUF902, CREBbp)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013178(H3K56 histone acetylation protein, RTT109)|interpro:IPR014744(Nuclear receptor coactivator, CREB-bp-like, interlocking)|interpro:IPR018359|interpro:IPR031162|interpro:IPR035898|interpro:IPR036427|interpro:IPR036529|interpro:IPR037073|interpro:IPR038547|interpro:IPR043145|reactome:R-SSC-1234158|reactome:R-SSC-201722|reactome:R-SSC-3134973|reactome:R-SSC-3371568|reactome:R-SSC-350054|reactome:R-SSC-5621575|reactome:R-SSC-8866907|reactome:R-SSC-8939246|reactome:R-SSC-8941856|reactome:R-SSC-918233|reactome:R-SSC-933541|reactome:R-SSC-9617629	go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033897"(ribonuclease T2 activity)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044228"(host cell surface)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0070008"(serine-type exopeptidase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000280(Peptidase S31, pestivurus polyprotein NS3/p80)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR008751(Peptidase C53, pestivirus Npro)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR021824|interpro:IPR022120|interpro:IPR027417|interpro:IPR030399|interpro:IPR032521|interpro:IPR033130|rcsb pdb:4H9J|rcsb pdb:4H9K|interpro:IPR042309|interpro:IPR042310|interpro:IPR042311|interpro:IPR036430|interpro:IPR042542|interpro:IPR043502|interpro:IPR043128	-	-	-	figure legend:4A|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/10/27	2017/12/04	rogid:9GdZtm0iq8h/k02WhMYzCL7KKlQ9823	rogid:Q5SceFsLg7z7DSoVZnGCx+9+kAI358769	rigid:3dwXxB/Nm6txFGWpSMl+vbwRWgo	false	mutation:2060-2061|binding-associated region:2061-2107	binding-associated region:1..1-168..168	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q68871	uniprotkb:Q764M6	intact:EBI-12522528	intact:EBI-12512266|ensembl:ENSSSCP00040008173	psi-mi:q68871_9flav(display_long)|uniprotkb:Capsid protein C(gene name synonym)|uniprotkb:Cysteine protease NS2(gene name synonym)|uniprotkb:"E(rns) glycoprotein"(gene name synonym)|uniprotkb:Envelope glycoprotein E1(gene name synonym)|uniprotkb:Envelope glycoprotein E2(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:N-terminal protease(gene name synonym)|uniprotkb:NS5B(gene name synonym)|uniprotkb:Non-structural protein 2(gene name synonym)|uniprotkb:Non-structural protein 2-3(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Non-structural protein 5A(gene name synonym)|uniprotkb:RNA-directed RNA polymerase(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:gp33(gene name synonym)|uniprotkb:gp44/48(gene name synonym)|uniprotkb:gp55(gene name synonym)|uniprotkb:Viroporin p7(gene name synonym)	psi-mi:irf3_pig(display_long)|uniprotkb:IRF3(gene name)|psi-mi:IRF3(display_short)	psi-mi:"MI:0071"(molecular sieving)	Gottipati et al. (2016)	pubmed:27334592|imex:IM-26098	taxid:358769(classical swine fever virus - alfort/187)|taxid:358769(classical swine fever virus - alfort/187)	taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-12595648|imex:IM-26098-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033897"(ribonuclease T2 activity)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044228"(host cell surface)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0070008"(serine-type exopeptidase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000280(Peptidase S31, pestivurus polyprotein NS3/p80)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR008751(Peptidase C53, pestivirus Npro)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR021824|interpro:IPR022120|interpro:IPR027417|interpro:IPR030399|interpro:IPR032521|interpro:IPR033130|rcsb pdb:4H9J|rcsb pdb:4H9K|interpro:IPR042309|interpro:IPR042310|interpro:IPR042311|interpro:IPR036430|interpro:IPR042542|interpro:IPR043502|interpro:IPR043128	ensembl:ENSSSCG00040014662(gene)|ensembl:ENSSSCT00040019663(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035666"(TRIF-dependent toll-like receptor signaling pathway)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|go:"GO:0098586"(cellular response to virus)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|reactome:R-SSC-1169408|reactome:R-SSC-1606341|reactome:R-SSC-168928|reactome:R-SSC-3134973|reactome:R-SSC-3134975|reactome:R-SSC-3270619|reactome:R-SSC-9013973|reactome:R-SSC-918233|reactome:R-SSC-933541|reactome:R-SSC-936440|reactome:R-SSC-936964|refseq:NP_998935.1	-	-	-	figure legend:1C, 2B|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/10/27	2016/11/08	rogid:Q5SceFsLg7z7DSoVZnGCx+9+kAI358769	rogid:k8mIgjpiImgr8GDDQbkAz1SlbfI9823	rigid:qT0WPVZ4a2LQXnI0SMfRILNxc7I	false	-	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:F1RK46	uniprotkb:Q764M6	intact:EBI-12595681|ensembl:ENSSSCP00000008490	intact:EBI-12512266|ensembl:ENSSSCP00040008173	psi-mi:f1rk46_pig(display_long)|uniprotkb:CREBBP(gene name)|psi-mi:CREBBP(display_short)	psi-mi:irf3_pig(display_long)|uniprotkb:IRF3(gene name)|psi-mi:IRF3(display_short)	psi-mi:"MI:0071"(molecular sieving)	Gottipati et al. (2016)	pubmed:27334592|imex:IM-26098	taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)")	taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-12595791|imex:IM-26098-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSSSCG00000007951(gene)|ensembl:ENSSSCT00000008714(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000785"(chromatin)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0002039"(p53 binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0018076"(N-terminal peptidyl-lysine acetylation)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0043426"(MRF binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048511"(rhythmic process)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1990258"(histone glutamine methylation)|interpro:IPR000197(Zinc finger, TAZ-type)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001487(Bromodomain)|interpro:IPR003101(Coactivator CBP, KIX)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010303(Protein of unknown function DUF902, CREBbp)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013178(H3K56 histone acetylation protein, RTT109)|interpro:IPR014744(Nuclear receptor coactivator, CREB-bp-like, interlocking)|interpro:IPR018359|interpro:IPR031162|interpro:IPR035898|interpro:IPR036427|interpro:IPR036529|interpro:IPR037073|interpro:IPR038547|interpro:IPR043145|reactome:R-SSC-1234158|reactome:R-SSC-201722|reactome:R-SSC-3134973|reactome:R-SSC-3371568|reactome:R-SSC-350054|reactome:R-SSC-5621575|reactome:R-SSC-8866907|reactome:R-SSC-8939246|reactome:R-SSC-8941856|reactome:R-SSC-918233|reactome:R-SSC-933541|reactome:R-SSC-9617629	ensembl:ENSSSCG00040014662(gene)|ensembl:ENSSSCT00040019663(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035666"(TRIF-dependent toll-like receptor signaling pathway)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|go:"GO:0098586"(cellular response to virus)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|reactome:R-SSC-1169408|reactome:R-SSC-1606341|reactome:R-SSC-168928|reactome:R-SSC-3134973|reactome:R-SSC-3134975|reactome:R-SSC-3270619|reactome:R-SSC-9013973|reactome:R-SSC-918233|reactome:R-SSC-933541|reactome:R-SSC-936440|reactome:R-SSC-936964|refseq:NP_998935.1	-	-	-	figure legend:3B|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/10/27	2017/12/04	rogid:9GdZtm0iq8h/k02WhMYzCL7KKlQ9823	rogid:k8mIgjpiImgr8GDDQbkAz1SlbfI9823	rigid:3dwXxB/Nm6txFGWpSMl+vbwRWgo	false	binding-associated region:2061-2107|mutation:2061-2061	mutation:384-384,396-396,394-394,400-400,402-402,403-403	-	1	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:F1RK46	uniprotkb:Q68871	intact:EBI-12595681|ensembl:ENSSSCP00000008490	intact:EBI-12522528	psi-mi:f1rk46_pig(display_long)|uniprotkb:CREBBP(gene name)|psi-mi:CREBBP(display_short)	psi-mi:q68871_9flav(display_long)|uniprotkb:Capsid protein C(gene name synonym)|uniprotkb:Cysteine protease NS2(gene name synonym)|uniprotkb:"E(rns) glycoprotein"(gene name synonym)|uniprotkb:Envelope glycoprotein E1(gene name synonym)|uniprotkb:Envelope glycoprotein E2(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:N-terminal protease(gene name synonym)|uniprotkb:NS5B(gene name synonym)|uniprotkb:Non-structural protein 2(gene name synonym)|uniprotkb:Non-structural protein 2-3(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Non-structural protein 5A(gene name synonym)|uniprotkb:RNA-directed RNA polymerase(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:gp33(gene name synonym)|uniprotkb:gp44/48(gene name synonym)|uniprotkb:gp55(gene name synonym)|uniprotkb:Viroporin p7(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Gottipati et al. (2016)	pubmed:27334592|imex:IM-26098	taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)")	taxid:358769(classical swine fever virus - alfort/187)|taxid:358769(classical swine fever virus - alfort/187)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-12595791|imex:IM-26098-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSSSCG00000007951(gene)|ensembl:ENSSSCT00000008714(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000785"(chromatin)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0002039"(p53 binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0018076"(N-terminal peptidyl-lysine acetylation)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0043426"(MRF binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048511"(rhythmic process)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1990258"(histone glutamine methylation)|interpro:IPR000197(Zinc finger, TAZ-type)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001487(Bromodomain)|interpro:IPR003101(Coactivator CBP, KIX)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010303(Protein of unknown function DUF902, CREBbp)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013178(H3K56 histone acetylation protein, RTT109)|interpro:IPR014744(Nuclear receptor coactivator, CREB-bp-like, interlocking)|interpro:IPR018359|interpro:IPR031162|interpro:IPR035898|interpro:IPR036427|interpro:IPR036529|interpro:IPR037073|interpro:IPR038547|interpro:IPR043145|reactome:R-SSC-1234158|reactome:R-SSC-201722|reactome:R-SSC-3134973|reactome:R-SSC-3371568|reactome:R-SSC-350054|reactome:R-SSC-5621575|reactome:R-SSC-8866907|reactome:R-SSC-8939246|reactome:R-SSC-8941856|reactome:R-SSC-918233|reactome:R-SSC-933541|reactome:R-SSC-9617629	go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033897"(ribonuclease T2 activity)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044228"(host cell surface)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0070008"(serine-type exopeptidase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000280(Peptidase S31, pestivurus polyprotein NS3/p80)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR008751(Peptidase C53, pestivirus Npro)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR021824|interpro:IPR022120|interpro:IPR027417|interpro:IPR030399|interpro:IPR032521|interpro:IPR033130|rcsb pdb:4H9J|rcsb pdb:4H9K|interpro:IPR042309|interpro:IPR042310|interpro:IPR042311|interpro:IPR036430|interpro:IPR042542|interpro:IPR043502|interpro:IPR043128	-	-	-	figure legend:3B|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/10/27	2017/12/04	rogid:9GdZtm0iq8h/k02WhMYzCL7KKlQ9823	rogid:Q5SceFsLg7z7DSoVZnGCx+9+kAI358769	rigid:3dwXxB/Nm6txFGWpSMl+vbwRWgo	false	binding-associated region:2061-2107|mutation:2061-2061	binding-associated region:1..1-168..168	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:F1RK46	uniprotkb:Q764M6	intact:EBI-12595681|ensembl:ENSSSCP00000008490	intact:EBI-12512266|ensembl:ENSSSCP00040008173	psi-mi:f1rk46_pig(display_long)|uniprotkb:CREBBP(gene name)|psi-mi:CREBBP(display_short)	psi-mi:irf3_pig(display_long)|uniprotkb:IRF3(gene name)|psi-mi:IRF3(display_short)	psi-mi:"MI:0071"(molecular sieving)	Gottipati et al. (2016)	pubmed:27334592|imex:IM-26098	taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)")	taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-12595806|imex:IM-26098-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSSSCG00000007951(gene)|ensembl:ENSSSCT00000008714(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000785"(chromatin)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0002039"(p53 binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0018076"(N-terminal peptidyl-lysine acetylation)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0043426"(MRF binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048511"(rhythmic process)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1990258"(histone glutamine methylation)|interpro:IPR000197(Zinc finger, TAZ-type)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001487(Bromodomain)|interpro:IPR003101(Coactivator CBP, KIX)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010303(Protein of unknown function DUF902, CREBbp)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013178(H3K56 histone acetylation protein, RTT109)|interpro:IPR014744(Nuclear receptor coactivator, CREB-bp-like, interlocking)|interpro:IPR018359|interpro:IPR031162|interpro:IPR035898|interpro:IPR036427|interpro:IPR036529|interpro:IPR037073|interpro:IPR038547|interpro:IPR043145|reactome:R-SSC-1234158|reactome:R-SSC-201722|reactome:R-SSC-3134973|reactome:R-SSC-3371568|reactome:R-SSC-350054|reactome:R-SSC-5621575|reactome:R-SSC-8866907|reactome:R-SSC-8939246|reactome:R-SSC-8941856|reactome:R-SSC-918233|reactome:R-SSC-933541|reactome:R-SSC-9617629	ensembl:ENSSSCG00040014662(gene)|ensembl:ENSSSCT00040019663(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035666"(TRIF-dependent toll-like receptor signaling pathway)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|go:"GO:0098586"(cellular response to virus)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|reactome:R-SSC-1169408|reactome:R-SSC-1606341|reactome:R-SSC-168928|reactome:R-SSC-3134973|reactome:R-SSC-3134975|reactome:R-SSC-3270619|reactome:R-SSC-9013973|reactome:R-SSC-918233|reactome:R-SSC-933541|reactome:R-SSC-936440|reactome:R-SSC-936964|refseq:NP_998935.1	-	-	-	figure legend:3B|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/10/27	2017/12/04	rogid:9GdZtm0iq8h/k02WhMYzCL7KKlQ9823	rogid:k8mIgjpiImgr8GDDQbkAz1SlbfI9823	rigid:3dwXxB/Nm6txFGWpSMl+vbwRWgo	false	binding-associated region:2061-2107|mutation:2061-2061	mutation:384-384,396-396,394-394,400-400,402-402,403-403	-	2	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:F1RK46	uniprotkb:Q68871	intact:EBI-12595681|ensembl:ENSSSCP00000008490	intact:EBI-12522528	psi-mi:f1rk46_pig(display_long)|uniprotkb:CREBBP(gene name)|psi-mi:CREBBP(display_short)	psi-mi:q68871_9flav(display_long)|uniprotkb:Capsid protein C(gene name synonym)|uniprotkb:Cysteine protease NS2(gene name synonym)|uniprotkb:"E(rns) glycoprotein"(gene name synonym)|uniprotkb:Envelope glycoprotein E1(gene name synonym)|uniprotkb:Envelope glycoprotein E2(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:N-terminal protease(gene name synonym)|uniprotkb:NS5B(gene name synonym)|uniprotkb:Non-structural protein 2(gene name synonym)|uniprotkb:Non-structural protein 2-3(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Non-structural protein 5A(gene name synonym)|uniprotkb:RNA-directed RNA polymerase(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:gp33(gene name synonym)|uniprotkb:gp44/48(gene name synonym)|uniprotkb:gp55(gene name synonym)|uniprotkb:Viroporin p7(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Gottipati et al. (2016)	pubmed:27334592|imex:IM-26098	taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)")	taxid:358769(classical swine fever virus - alfort/187)|taxid:358769(classical swine fever virus - alfort/187)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-12595806|imex:IM-26098-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSSSCG00000007951(gene)|ensembl:ENSSSCT00000008714(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000785"(chromatin)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0002039"(p53 binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0018076"(N-terminal peptidyl-lysine acetylation)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0043426"(MRF binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048511"(rhythmic process)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1990258"(histone glutamine methylation)|interpro:IPR000197(Zinc finger, TAZ-type)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001487(Bromodomain)|interpro:IPR003101(Coactivator CBP, KIX)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010303(Protein of unknown function DUF902, CREBbp)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013178(H3K56 histone acetylation protein, RTT109)|interpro:IPR014744(Nuclear receptor coactivator, CREB-bp-like, interlocking)|interpro:IPR018359|interpro:IPR031162|interpro:IPR035898|interpro:IPR036427|interpro:IPR036529|interpro:IPR037073|interpro:IPR038547|interpro:IPR043145|reactome:R-SSC-1234158|reactome:R-SSC-201722|reactome:R-SSC-3134973|reactome:R-SSC-3371568|reactome:R-SSC-350054|reactome:R-SSC-5621575|reactome:R-SSC-8866907|reactome:R-SSC-8939246|reactome:R-SSC-8941856|reactome:R-SSC-918233|reactome:R-SSC-933541|reactome:R-SSC-9617629	go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033897"(ribonuclease T2 activity)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044228"(host cell surface)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0070008"(serine-type exopeptidase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000280(Peptidase S31, pestivurus polyprotein NS3/p80)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR008751(Peptidase C53, pestivirus Npro)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR021824|interpro:IPR022120|interpro:IPR027417|interpro:IPR030399|interpro:IPR032521|interpro:IPR033130|rcsb pdb:4H9J|rcsb pdb:4H9K|interpro:IPR042309|interpro:IPR042310|interpro:IPR042311|interpro:IPR036430|interpro:IPR042542|interpro:IPR043502|interpro:IPR043128	-	-	-	figure legend:3B|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/10/27	2017/12/04	rogid:9GdZtm0iq8h/k02WhMYzCL7KKlQ9823	rogid:Q5SceFsLg7z7DSoVZnGCx+9+kAI358769	rigid:3dwXxB/Nm6txFGWpSMl+vbwRWgo	false	binding-associated region:2061-2107|mutation:2061-2061	binding-associated region:1..1-168..168	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:F1RK46	uniprotkb:Q764M6	intact:EBI-12595681|ensembl:ENSSSCP00000008490	intact:EBI-12512266|ensembl:ENSSSCP00040008173	psi-mi:f1rk46_pig(display_long)|uniprotkb:CREBBP(gene name)|psi-mi:CREBBP(display_short)	psi-mi:irf3_pig(display_long)|uniprotkb:IRF3(gene name)|psi-mi:IRF3(display_short)	psi-mi:"MI:0071"(molecular sieving)	Gottipati et al. (2016)	pubmed:27334592|imex:IM-26098	taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)")	taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-12595828|imex:IM-26098-17	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSSSCG00000007951(gene)|ensembl:ENSSSCT00000008714(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000785"(chromatin)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0002039"(p53 binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0018076"(N-terminal peptidyl-lysine acetylation)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0043426"(MRF binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048511"(rhythmic process)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1990258"(histone glutamine methylation)|interpro:IPR000197(Zinc finger, TAZ-type)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001487(Bromodomain)|interpro:IPR003101(Coactivator CBP, KIX)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010303(Protein of unknown function DUF902, CREBbp)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013178(H3K56 histone acetylation protein, RTT109)|interpro:IPR014744(Nuclear receptor coactivator, CREB-bp-like, interlocking)|interpro:IPR018359|interpro:IPR031162|interpro:IPR035898|interpro:IPR036427|interpro:IPR036529|interpro:IPR037073|interpro:IPR038547|interpro:IPR043145|reactome:R-SSC-1234158|reactome:R-SSC-201722|reactome:R-SSC-3134973|reactome:R-SSC-3371568|reactome:R-SSC-350054|reactome:R-SSC-5621575|reactome:R-SSC-8866907|reactome:R-SSC-8939246|reactome:R-SSC-8941856|reactome:R-SSC-918233|reactome:R-SSC-933541|reactome:R-SSC-9617629	ensembl:ENSSSCG00040014662(gene)|ensembl:ENSSSCT00040019663(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035666"(TRIF-dependent toll-like receptor signaling pathway)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|go:"GO:0098586"(cellular response to virus)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|reactome:R-SSC-1169408|reactome:R-SSC-1606341|reactome:R-SSC-168928|reactome:R-SSC-3134973|reactome:R-SSC-3134975|reactome:R-SSC-3270619|reactome:R-SSC-9013973|reactome:R-SSC-918233|reactome:R-SSC-933541|reactome:R-SSC-936440|reactome:R-SSC-936964|refseq:NP_998935.1	-	-	-	figure legend:4B|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/10/27	2017/12/04	rogid:9GdZtm0iq8h/k02WhMYzCL7KKlQ9823	rogid:k8mIgjpiImgr8GDDQbkAz1SlbfI9823	rigid:3dwXxB/Nm6txFGWpSMl+vbwRWgo	false	binding-associated region:2061-2107|multisulfide crosslinked residues:2061-2061,2061-2061	sufficient binding region:392-419	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:F1RK46	uniprotkb:Q68871	intact:EBI-12595681|ensembl:ENSSSCP00000008490	intact:EBI-12522528	psi-mi:f1rk46_pig(display_long)|uniprotkb:CREBBP(gene name)|psi-mi:CREBBP(display_short)	psi-mi:q68871_9flav(display_long)|uniprotkb:Capsid protein C(gene name synonym)|uniprotkb:Cysteine protease NS2(gene name synonym)|uniprotkb:"E(rns) glycoprotein"(gene name synonym)|uniprotkb:Envelope glycoprotein E1(gene name synonym)|uniprotkb:Envelope glycoprotein E2(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:N-terminal protease(gene name synonym)|uniprotkb:NS5B(gene name synonym)|uniprotkb:Non-structural protein 2(gene name synonym)|uniprotkb:Non-structural protein 2-3(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Non-structural protein 5A(gene name synonym)|uniprotkb:RNA-directed RNA polymerase(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:gp33(gene name synonym)|uniprotkb:gp44/48(gene name synonym)|uniprotkb:gp55(gene name synonym)|uniprotkb:Viroporin p7(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Gottipati et al. (2016)	pubmed:27334592|imex:IM-26098	taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)")	taxid:358769(classical swine fever virus - alfort/187)|taxid:358769(classical swine fever virus - alfort/187)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-12595828|imex:IM-26098-17	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSSSCG00000007951(gene)|ensembl:ENSSSCT00000008714(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000785"(chromatin)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0002039"(p53 binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0018076"(N-terminal peptidyl-lysine acetylation)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0043426"(MRF binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048511"(rhythmic process)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1990258"(histone glutamine methylation)|interpro:IPR000197(Zinc finger, TAZ-type)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001487(Bromodomain)|interpro:IPR003101(Coactivator CBP, KIX)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010303(Protein of unknown function DUF902, CREBbp)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013178(H3K56 histone acetylation protein, RTT109)|interpro:IPR014744(Nuclear receptor coactivator, CREB-bp-like, interlocking)|interpro:IPR018359|interpro:IPR031162|interpro:IPR035898|interpro:IPR036427|interpro:IPR036529|interpro:IPR037073|interpro:IPR038547|interpro:IPR043145|reactome:R-SSC-1234158|reactome:R-SSC-201722|reactome:R-SSC-3134973|reactome:R-SSC-3371568|reactome:R-SSC-350054|reactome:R-SSC-5621575|reactome:R-SSC-8866907|reactome:R-SSC-8939246|reactome:R-SSC-8941856|reactome:R-SSC-918233|reactome:R-SSC-933541|reactome:R-SSC-9617629	go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033897"(ribonuclease T2 activity)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044228"(host cell surface)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0070008"(serine-type exopeptidase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000280(Peptidase S31, pestivurus polyprotein NS3/p80)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR008751(Peptidase C53, pestivirus Npro)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR021824|interpro:IPR022120|interpro:IPR027417|interpro:IPR030399|interpro:IPR032521|interpro:IPR033130|rcsb pdb:4H9J|rcsb pdb:4H9K|interpro:IPR042309|interpro:IPR042310|interpro:IPR042311|interpro:IPR036430|interpro:IPR042542|interpro:IPR043502|interpro:IPR043128	-	-	-	figure legend:4B|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/10/27	2017/12/04	rogid:9GdZtm0iq8h/k02WhMYzCL7KKlQ9823	rogid:Q5SceFsLg7z7DSoVZnGCx+9+kAI358769	rigid:3dwXxB/Nm6txFGWpSMl+vbwRWgo	false	binding-associated region:2061-2107|multisulfide crosslinked residues:2061-2061,2061-2061	binding-associated region:1..1-168..168	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q68871	uniprotkb:Q764M6	intact:EBI-12522528	intact:EBI-12512266|ensembl:ENSSSCP00040008173	psi-mi:q68871_9flav(display_long)|uniprotkb:Capsid protein C(gene name synonym)|uniprotkb:Cysteine protease NS2(gene name synonym)|uniprotkb:"E(rns) glycoprotein"(gene name synonym)|uniprotkb:Envelope glycoprotein E1(gene name synonym)|uniprotkb:Envelope glycoprotein E2(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:N-terminal protease(gene name synonym)|uniprotkb:NS5B(gene name synonym)|uniprotkb:Non-structural protein 2(gene name synonym)|uniprotkb:Non-structural protein 2-3(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Non-structural protein 5A(gene name synonym)|uniprotkb:RNA-directed RNA polymerase(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:gp33(gene name synonym)|uniprotkb:gp44/48(gene name synonym)|uniprotkb:gp55(gene name synonym)|uniprotkb:Viroporin p7(gene name synonym)	psi-mi:irf3_pig(display_long)|uniprotkb:IRF3(gene name)|psi-mi:IRF3(display_short)	psi-mi:"MI:0028"(cosedimentation in solution)	Gottipati et al. (2016)	pubmed:27334592|imex:IM-26098	taxid:358769(classical swine fever virus - alfort/187)|taxid:358769(classical swine fever virus - alfort/187)	taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-12595664|imex:IM-26098-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033897"(ribonuclease T2 activity)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044228"(host cell surface)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0070008"(serine-type exopeptidase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000280(Peptidase S31, pestivurus polyprotein NS3/p80)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR008751(Peptidase C53, pestivirus Npro)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR021824|interpro:IPR022120|interpro:IPR027417|interpro:IPR030399|interpro:IPR032521|interpro:IPR033130|rcsb pdb:4H9J|rcsb pdb:4H9K|interpro:IPR042309|interpro:IPR042310|interpro:IPR042311|interpro:IPR036430|interpro:IPR042542|interpro:IPR043502|interpro:IPR043128	ensembl:ENSSSCG00040014662(gene)|ensembl:ENSSSCT00040019663(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035666"(TRIF-dependent toll-like receptor signaling pathway)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|go:"GO:0098586"(cellular response to virus)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|reactome:R-SSC-1169408|reactome:R-SSC-1606341|reactome:R-SSC-168928|reactome:R-SSC-3134973|reactome:R-SSC-3134975|reactome:R-SSC-3270619|reactome:R-SSC-9013973|reactome:R-SSC-918233|reactome:R-SSC-933541|reactome:R-SSC-936440|reactome:R-SSC-936964|refseq:NP_998935.1	-	-	-	figure legend:1D|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/10/27	2016/12/16	rogid:Q5SceFsLg7z7DSoVZnGCx+9+kAI358769	rogid:k8mIgjpiImgr8GDDQbkAz1SlbfI9823	rigid:qT0WPVZ4a2LQXnI0SMfRILNxc7I	false	binding-associated region:1..1-168..168	-	1	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)