#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O14625-PRO_0000005106 uniprotkb:P98066 intact:EBI-11711364 intact:EBI-11700693|uniprotkb:Q53TI7|uniprotkb:Q8WWI9|ensembl:ENSP00000243347 psi-mi:o14625-pro_0000005106(display_long)|uniprotkb:Beta-R1(gene name synonym)|uniprotkb:H174(gene name synonym)|uniprotkb:Interferon gamma-inducible protein 9(gene name synonym)|uniprotkb:Interferon-inducible T-cell alpha chemoattractant(gene name synonym)|uniprotkb:Small-inducible cytokine B11(gene name synonym)|uniprotkb:CXCL11(gene name)|psi-mi:CXCL11(display_short)|uniprotkb:ITAC(gene name synonym)|uniprotkb:SCYB11(gene name synonym)|uniprotkb:SCYB9B(gene name synonym) psi-mi:tsg6_human(display_long)|uniprotkb:TSG6(gene name synonym)|uniprotkb:TNFAIP6(gene name)|psi-mi:TNFAIP6(display_short)|uniprotkb:Hyaluronate-binding protein(gene name synonym)|uniprotkb:TNF-stimulated gene 6 protein(gene name synonym)|uniprotkb:Tumor necrosis factor alpha-induced protein 6(gene name synonym) psi-mi:"MI:0107"(surface plasmon resonance) Dyer et al. (2016) pubmed:27044744|imex:IM-25309 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-11711359|imex:IM-25309-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2871971(chain-parent) refseq:NP_009046.2|ensembl:ENSG00000123610(gene)|ensembl:ENST00000243347(transcript)|go:"GO:0005540"(hyaluronic acid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006954"(inflammatory response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030728"(ovulation)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000538(Link)|interpro:IPR000859(CUB)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR035914|rcsb pdb:1O7B|rcsb pdb:1O7C|rcsb pdb:2N40|rcsb pdb:2PF5|rcsb pdb:2WNO|reactome:R-HSA-6798695 - chain-seq-start:22|chain-seq-end:94 - figure legend:1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:5.2x10^-9(molar) 2016/05/05 2016/06/07 rogid:+8aPUFAAe6mwzXVfmoNp0dGuTMM9606 rogid:2Ea1tHjyixlxoJd7hef0CyUkjgk9606 rigid:EWXNOJCyZ8ytaruPB84cG/4gHPg false - sufficient binding region:36-133 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P48061-PRO_0000005109 uniprotkb:P98066 intact:EBI-11711379 intact:EBI-11700693|uniprotkb:Q53TI7|uniprotkb:Q8WWI9|ensembl:ENSP00000243347 psi-mi:p48061-pro_0000005109(display_long)|uniprotkb:C-X-C motif chemokine 12(gene name synonym)|uniprotkb:Intercrine reduced in hepatomas(gene name synonym)|uniprotkb:Pre-B cell growth-stimulating factor(gene name synonym)|uniprotkb:CXCL12(gene name)|psi-mi:CXCL12(display_short)|uniprotkb:SDF1(gene name synonym)|uniprotkb:SDF1A(gene name synonym)|uniprotkb:SDF1B(gene name synonym) psi-mi:tsg6_human(display_long)|uniprotkb:TSG6(gene name synonym)|uniprotkb:TNFAIP6(gene name)|psi-mi:TNFAIP6(display_short)|uniprotkb:Hyaluronate-binding protein(gene name synonym)|uniprotkb:TNF-stimulated gene 6 protein(gene name synonym)|uniprotkb:Tumor necrosis factor alpha-induced protein 6(gene name synonym) psi-mi:"MI:0107"(surface plasmon resonance) Dyer et al. (2016) pubmed:27044744|imex:IM-25309 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-11711373|imex:IM-25309-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-3913254(chain-parent) refseq:NP_009046.2|ensembl:ENSG00000123610(gene)|ensembl:ENST00000243347(transcript)|go:"GO:0005540"(hyaluronic acid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006954"(inflammatory response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030728"(ovulation)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000538(Link)|interpro:IPR000859(CUB)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR035914|rcsb pdb:1O7B|rcsb pdb:1O7C|rcsb pdb:2N40|rcsb pdb:2PF5|rcsb pdb:2WNO|reactome:R-HSA-6798695 - chain-seq-start:22|chain-seq-end:93 - figure legend:1 C/D, 2E|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:15.0x10^-9(molar) 2016/05/05 2016/06/16 rogid:bo7P08PahELl+/ajJqDAPlS0VM49606 rogid:2Ea1tHjyixlxoJd7hef0CyUkjgk9606 rigid:dQ4jRh3/NU7VJcPjzbvIsdDgxko false mutation decreasing interaction strength:24-25,27-27 sufficient binding region:36-133 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P13500-PRO_0000005146 uniprotkb:P98066 intact:EBI-11711396 intact:EBI-11700693|uniprotkb:Q53TI7|uniprotkb:Q8WWI9|ensembl:ENSP00000243347 psi-mi:p13500-pro_0000005146(display_long)|uniprotkb:HC11(gene name synonym)|uniprotkb:Monocyte chemoattractant protein 1(gene name synonym)|uniprotkb:Monocyte chemotactic and activating factor(gene name synonym)|uniprotkb:Monocyte chemotactic protein 1(gene name synonym)|uniprotkb:Monocyte secretory protein JE(gene name synonym)|uniprotkb:Small-inducible cytokine A2(gene name synonym)|uniprotkb:CCL2(gene name)|psi-mi:CCL2(display_short)|uniprotkb:MCP1(gene name synonym)|uniprotkb:SCYA2(gene name synonym) psi-mi:tsg6_human(display_long)|uniprotkb:TSG6(gene name synonym)|uniprotkb:TNFAIP6(gene name)|psi-mi:TNFAIP6(display_short)|uniprotkb:Hyaluronate-binding protein(gene name synonym)|uniprotkb:TNF-stimulated gene 6 protein(gene name synonym)|uniprotkb:Tumor necrosis factor alpha-induced protein 6(gene name synonym) psi-mi:"MI:0107"(surface plasmon resonance) Dyer et al. (2016) pubmed:27044744|imex:IM-25309 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-11711387|imex:IM-25309-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1034732(chain-parent) refseq:NP_009046.2|ensembl:ENSG00000123610(gene)|ensembl:ENST00000243347(transcript)|go:"GO:0005540"(hyaluronic acid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006954"(inflammatory response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030728"(ovulation)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000538(Link)|interpro:IPR000859(CUB)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR035914|rcsb pdb:1O7B|rcsb pdb:1O7C|rcsb pdb:2N40|rcsb pdb:2PF5|rcsb pdb:2WNO|reactome:R-HSA-6798695 - chain-seq-start:24|chain-seq-end:99 - figure legend:1E, 2A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:29.4x10^-9(molar) 2016/05/05 2016/06/16 rogid:GwGcN1L+gGK666Lo2ho6bOTl1IA9606 rogid:2Ea1tHjyixlxoJd7hef0CyUkjgk9606 rigid:pg/voRVKHraq39sPrz6Y31fkey8 false mutation disrupting interaction strength:18-19 sufficient binding region:36-133 1 1 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P80098-PRO_0000005183 uniprotkb:P98066 intact:EBI-11711410 intact:EBI-11700693|uniprotkb:Q53TI7|uniprotkb:Q8WWI9|ensembl:ENSP00000243347 psi-mi:p80098-pro_0000005183(display_long)|uniprotkb:CCL7(gene name)|psi-mi:CCL7(display_short)|uniprotkb:MCP3(gene name synonym)|uniprotkb:SCYA6(gene name synonym)|uniprotkb:SCYA7(gene name synonym)|uniprotkb:Monocyte chemoattractant protein 3(gene name synonym)|uniprotkb:Monocyte chemotactic protein 3(gene name synonym)|uniprotkb:NC28(gene name synonym)|uniprotkb:Small-inducible cytokine A7(gene name synonym) psi-mi:tsg6_human(display_long)|uniprotkb:TSG6(gene name synonym)|uniprotkb:TNFAIP6(gene name)|psi-mi:TNFAIP6(display_short)|uniprotkb:Hyaluronate-binding protein(gene name synonym)|uniprotkb:TNF-stimulated gene 6 protein(gene name synonym)|uniprotkb:Tumor necrosis factor alpha-induced protein 6(gene name synonym) psi-mi:"MI:0107"(surface plasmon resonance) Dyer et al. (2016) pubmed:27044744|imex:IM-25309 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-11711404|imex:IM-25309-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-718759(chain-parent) refseq:NP_009046.2|ensembl:ENSG00000123610(gene)|ensembl:ENST00000243347(transcript)|go:"GO:0005540"(hyaluronic acid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006954"(inflammatory response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030728"(ovulation)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000538(Link)|interpro:IPR000859(CUB)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR035914|rcsb pdb:1O7B|rcsb pdb:1O7C|rcsb pdb:2N40|rcsb pdb:2PF5|rcsb pdb:2WNO|reactome:R-HSA-6798695 - chain-seq-start:24|chain-seq-end:99 - figure legend:1F, 2D|comment:There was a weak interaction with the CCL7 K18A/K19A/K22A mutant; there was insufficient signal to calculate a Kd value.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:18.4x10^-9(molar) 2016/05/05 2016/06/16 rogid:dXg99QDACCGoX9nmdsytX7CZFZY9606 rogid:2Ea1tHjyixlxoJd7hef0CyUkjgk9606 rigid:Blpb3YxjPX6GAqkRO0YoqiyhatQ false mutation decreasing interaction strength:18-19,22-22 sufficient binding region:36-133 1 1 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99731-PRO_0000005214 uniprotkb:P98066 intact:EBI-11711510 intact:EBI-11700693|uniprotkb:Q53TI7|uniprotkb:Q8WWI9|ensembl:ENSP00000243347 psi-mi:q99731-pro_0000005214(display_long)|uniprotkb:CCL19(gene name)|psi-mi:CCL19(display_short)|uniprotkb:ELC(gene name synonym)|uniprotkb:MIP3B(gene name synonym)|uniprotkb:SCYA19(gene name synonym)|uniprotkb:Beta-chemokine exodus-3(gene name synonym)|uniprotkb:CK beta-11(gene name synonym)|uniprotkb:Epstein-Barr virus-induced molecule 1 ligand chemokine(gene name synonym)|uniprotkb:Macrophage inflammatory protein 3 beta(gene name synonym)|uniprotkb:Small-inducible cytokine A19(gene name synonym) psi-mi:tsg6_human(display_long)|uniprotkb:TSG6(gene name synonym)|uniprotkb:TNFAIP6(gene name)|psi-mi:TNFAIP6(display_short)|uniprotkb:Hyaluronate-binding protein(gene name synonym)|uniprotkb:TNF-stimulated gene 6 protein(gene name synonym)|uniprotkb:Tumor necrosis factor alpha-induced protein 6(gene name synonym) psi-mi:"MI:0107"(surface plasmon resonance) Dyer et al. (2016) pubmed:27044744|imex:IM-25309 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-11711428|imex:IM-25309-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-11711434(chain-parent) refseq:NP_009046.2|ensembl:ENSG00000123610(gene)|ensembl:ENST00000243347(transcript)|go:"GO:0005540"(hyaluronic acid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006954"(inflammatory response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030728"(ovulation)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000538(Link)|interpro:IPR000859(CUB)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR035914|rcsb pdb:1O7B|rcsb pdb:1O7C|rcsb pdb:2N40|rcsb pdb:2PF5|rcsb pdb:2WNO|reactome:R-HSA-6798695 - chain-seq-start:22|chain-seq-end:98 - figure legend:1G|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:17.5x10^-9(molar) 2016/05/05 2016/06/07 rogid:cx66QgixUzcWKwv9HGYLfGGfwU49606 rogid:2Ea1tHjyixlxoJd7hef0CyUkjgk9606 rigid:RSyl5au79DXHw/pACGMTm2IhWvo false - sufficient binding region:36-133 1 1 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O00585-PRO_0000005220 uniprotkb:P98066 intact:EBI-11711534 intact:EBI-11700693|uniprotkb:Q53TI7|uniprotkb:Q8WWI9|ensembl:ENSP00000243347 psi-mi:o00585-pro_0000005220(display_long)|uniprotkb:CCL21(gene name)|psi-mi:CCL21(display_short)|uniprotkb:SCYA21(gene name synonym)|uniprotkb:6Ckine(gene name synonym)|uniprotkb:Beta-chemokine exodus-2(gene name synonym)|uniprotkb:Secondary lymphoid-tissue chemokine(gene name synonym)|uniprotkb:Small-inducible cytokine A21(gene name synonym)|uniprotkb:UNQ784/PRO1600(orf name) psi-mi:tsg6_human(display_long)|uniprotkb:TSG6(gene name synonym)|uniprotkb:TNFAIP6(gene name)|psi-mi:TNFAIP6(display_short)|uniprotkb:Hyaluronate-binding protein(gene name synonym)|uniprotkb:TNF-stimulated gene 6 protein(gene name synonym)|uniprotkb:Tumor necrosis factor alpha-induced protein 6(gene name synonym) psi-mi:"MI:0107"(surface plasmon resonance) Dyer et al. (2016) pubmed:27044744|imex:IM-25309 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-11711524|imex:IM-25309-17 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-953695(chain-parent) refseq:NP_009046.2|ensembl:ENSG00000123610(gene)|ensembl:ENST00000243347(transcript)|go:"GO:0005540"(hyaluronic acid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006954"(inflammatory response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030728"(ovulation)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000538(Link)|interpro:IPR000859(CUB)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR035914|rcsb pdb:1O7B|rcsb pdb:1O7C|rcsb pdb:2N40|rcsb pdb:2PF5|rcsb pdb:2WNO|reactome:R-HSA-6798695 - chain-seq-start:24|chain-seq-end:134 - figure legend:1H, 2C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:4.8x10^-9(molar) 2016/05/05 2016/06/07 rogid:B5E346w51FBhOecoLufB126LwDs9606 rogid:2Ea1tHjyixlxoJd7hef0CyUkjgk9606 rigid:sABN5q5vJHi7RT0VSU11ypXw3sM false necessary binding region:80-111 sufficient binding region:36-133 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Y4X3-PRO_0000005239 uniprotkb:P98066 intact:EBI-11711551 intact:EBI-11700693|uniprotkb:Q53TI7|uniprotkb:Q8WWI9|ensembl:ENSP00000243347 psi-mi:pro_0000005239(display_long)|uniprotkb:CCL27(gene name)|psi-mi:CCL27(display_short)|uniprotkb:ILC(gene name synonym)|uniprotkb:SCYA27(gene name synonym) psi-mi:tsg6_human(display_long)|uniprotkb:TSG6(gene name synonym)|uniprotkb:TNFAIP6(gene name)|psi-mi:TNFAIP6(display_short)|uniprotkb:Hyaluronate-binding protein(gene name synonym)|uniprotkb:TNF-stimulated gene 6 protein(gene name synonym)|uniprotkb:Tumor necrosis factor alpha-induced protein 6(gene name synonym) psi-mi:"MI:0107"(surface plasmon resonance) Dyer et al. (2016) pubmed:27044744|imex:IM-25309 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-11711543|imex:IM-25309-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9Y4X3(chain-parent) refseq:NP_009046.2|ensembl:ENSG00000123610(gene)|ensembl:ENST00000243347(transcript)|go:"GO:0005540"(hyaluronic acid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006954"(inflammatory response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030728"(ovulation)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000538(Link)|interpro:IPR000859(CUB)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR035914|rcsb pdb:1O7B|rcsb pdb:1O7C|rcsb pdb:2N40|rcsb pdb:2PF5|rcsb pdb:2WNO|reactome:R-HSA-6798695 - - - figure legend:1 I/J, 2F|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:85.2x10^-9(molar) 2016/05/05 2016/06/16 rogid:Gx6A2cBJ48nZAoVusPERXhTC4dM9606 rogid:2Ea1tHjyixlxoJd7hef0CyUkjgk9606 rigid:O5jxcrvID66pIVHEu2JObbyyKv8 false mutation decreasing interaction strength:25-25 sufficient binding region:36-133 1 1 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P13501-PRO_0000005175 uniprotkb:P98066 intact:EBI-11712923 intact:EBI-11700693|uniprotkb:Q53TI7|uniprotkb:Q8WWI9|ensembl:ENSP00000243347 psi-mi:p13501-pro_0000005175(display_long)|uniprotkb:Eosinophil chemotactic cytokine(gene name synonym)|uniprotkb:SIS-delta(gene name synonym)|uniprotkb:Small-inducible cytokine A5(gene name synonym)|uniprotkb:T cell-specific protein P228(gene name synonym)|uniprotkb:T-cell-specific protein RANTES(gene name synonym)|uniprotkb:EoCP(gene name synonym)|uniprotkb:D17S136E(gene name synonym)|uniprotkb:SCYA5(gene name synonym)|uniprotkb:CCL5(gene name)|psi-mi:CCL5(display_short) psi-mi:tsg6_human(display_long)|uniprotkb:TSG6(gene name synonym)|uniprotkb:TNFAIP6(gene name)|psi-mi:TNFAIP6(display_short)|uniprotkb:Hyaluronate-binding protein(gene name synonym)|uniprotkb:TNF-stimulated gene 6 protein(gene name synonym)|uniprotkb:Tumor necrosis factor alpha-induced protein 6(gene name synonym) psi-mi:"MI:0107"(surface plasmon resonance) Dyer et al. (2016) pubmed:27044744|imex:IM-25309 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-11712915|imex:IM-25309-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2848366(chain-parent) refseq:NP_009046.2|ensembl:ENSG00000123610(gene)|ensembl:ENST00000243347(transcript)|go:"GO:0005540"(hyaluronic acid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006954"(inflammatory response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030728"(ovulation)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000538(Link)|interpro:IPR000859(CUB)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR035914|rcsb pdb:1O7B|rcsb pdb:1O7C|rcsb pdb:2N40|rcsb pdb:2PF5|rcsb pdb:2WNO|reactome:R-HSA-6798695 - chain-seq-start:24|chain-seq-end:91 - figure legend:2B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/05/05 2016/06/16 rogid:u9kg21gHq0UCwtqoDeVlpa/Uc9E9606 rogid:2Ea1tHjyixlxoJd7hef0CyUkjgk9606 rigid:Up8sBadgolYmYgcj0ak6grhw190 false mutation disrupting interaction strength:44-45,47-47 sufficient binding region:36-133 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P02776 uniprotkb:P98066 intact:EBI-2565740|uniprotkb:Q53X61|uniprotkb:Q9UC64|uniprotkb:Q9UC65|ensembl:ENSP00000296029 intact:EBI-11700693|uniprotkb:Q53TI7|uniprotkb:Q8WWI9|ensembl:ENSP00000243347 psi-mi:plf4_human(display_long)|uniprotkb:PF4(gene name)|psi-mi:PF4(display_short)|uniprotkb:CXCL4(gene name synonym)|uniprotkb:SCYB4(gene name synonym)|uniprotkb:C-X-C motif chemokine 4(gene name synonym)|uniprotkb:Oncostatin-A(gene name synonym)|uniprotkb:Iroplact(gene name synonym) psi-mi:tsg6_human(display_long)|uniprotkb:TSG6(gene name synonym)|uniprotkb:TNFAIP6(gene name)|psi-mi:TNFAIP6(display_short)|uniprotkb:Hyaluronate-binding protein(gene name synonym)|uniprotkb:TNF-stimulated gene 6 protein(gene name synonym)|uniprotkb:Tumor necrosis factor alpha-induced protein 6(gene name synonym) psi-mi:"MI:0107"(surface plasmon resonance) Dyer et al. (2016) pubmed:27044744|imex:IM-25309 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-11738838|imex:IM-25309-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002610.1|ensembl:ENSG00000163737(gene)|ensembl:ENST00000296029(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0006954"(inflammatory response)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0008009"(chemokine activity)|go:"GO:0008201"(heparin binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010744"(positive regulation of macrophage derived foam cell differentiation)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0020005"(symbiont-containing vacuole membrane)|go:"GO:0030168"(platelet activation)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0030595"(leukocyte chemotaxis)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0045236"(CXCR chemokine receptor binding)|go:"GO:0045347"(negative regulation of MHC class II biosynthetic process)|go:"GO:0045651"(positive regulation of macrophage differentiation)|go:"GO:0045653"(negative regulation of megakaryocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048248"(CXCR3 chemokine receptor binding)|go:"GO:0051873"(killing by host of symbiont cells)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070098"(chemokine-mediated signaling pathway)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001089(Small chemokine, C-X-C)|interpro:IPR001811(Small chemokine, interleukin-8-like)|interpro:IPR018048|interpro:IPR027222|interpro:IPR033899|interpro:IPR036048|mint:P02776|rcsb pdb:1DN3|rcsb pdb:1F9Q|rcsb pdb:1F9R|rcsb pdb:1F9S|rcsb pdb:1PFM|rcsb pdb:1PFN|rcsb pdb:1RHP|rcsb pdb:4R9W|rcsb pdb:4R9Y|rcsb pdb:4RAU|reactome:R-HSA-114608|reactome:R-HSA-140875|reactome:R-HSA-202733|reactome:R-HSA-380108|reactome:R-HSA-418594|reactome:R-HSA-8936459|dip:DIP-56941N refseq:NP_009046.2|ensembl:ENSG00000123610(gene)|ensembl:ENST00000243347(transcript)|go:"GO:0005540"(hyaluronic acid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006954"(inflammatory response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030728"(ovulation)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000538(Link)|interpro:IPR000859(CUB)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR035914|rcsb pdb:1O7B|rcsb pdb:1O7C|rcsb pdb:2N40|rcsb pdb:2PF5|rcsb pdb:2WNO|reactome:R-HSA-6798695 - - - figure legend:1A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:3.9x10^-9(molar) 2016/05/05 2016/06/16 rogid:7jf/vdPXt9JwZzkBEW8jO8dC6f09606 rogid:2Ea1tHjyixlxoJd7hef0CyUkjgk9606 rigid:Y8/MaC1PM3NkTxcg7EHjS9fiVUs false sufficient binding region:32..48-101 sufficient binding region:36-133 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:28304" uniprotkb:P98066 intact:EBI-1379423 intact:EBI-11700693|uniprotkb:Q53TI7|uniprotkb:Q8WWI9|ensembl:ENSP00000243347 psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long) psi-mi:tsg6_human(display_long)|uniprotkb:TSG6(gene name synonym)|uniprotkb:TNFAIP6(gene name)|psi-mi:TNFAIP6(display_short)|uniprotkb:Hyaluronate-binding protein(gene name synonym)|uniprotkb:TNF-stimulated gene 6 protein(gene name synonym)|uniprotkb:Tumor necrosis factor alpha-induced protein 6(gene name synonym) psi-mi:"MI:0107"(surface plasmon resonance) Dyer et al. (2016) pubmed:27044744|imex:IM-25309 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-11739192|imex:IM-25309-24 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_009046.2|ensembl:ENSG00000123610(gene)|ensembl:ENST00000243347(transcript)|go:"GO:0005540"(hyaluronic acid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006954"(inflammatory response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030728"(ovulation)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000538(Link)|interpro:IPR000859(CUB)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR035914|rcsb pdb:1O7B|rcsb pdb:1O7C|rcsb pdb:2N40|rcsb pdb:2PF5|rcsb pdb:2WNO|reactome:R-HSA-6798695 - - - figure legend:7|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:22.0x10^-9(molar) 2016/05/05 2016/06/16 - rogid:2Ea1tHjyixlxoJd7hef0CyUkjgk9606 - false - sufficient binding region:36-133 1 1 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:28304" uniprotkb:O14625-PRO_0000005106 intact:EBI-1379423 intact:EBI-11711364 psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long) psi-mi:o14625-pro_0000005106(display_long)|uniprotkb:Beta-R1(gene name synonym)|uniprotkb:H174(gene name synonym)|uniprotkb:Interferon gamma-inducible protein 9(gene name synonym)|uniprotkb:Interferon-inducible T-cell alpha chemoattractant(gene name synonym)|uniprotkb:Small-inducible cytokine B11(gene name synonym)|uniprotkb:CXCL11(gene name)|psi-mi:CXCL11(display_short)|uniprotkb:ITAC(gene name synonym)|uniprotkb:SCYB11(gene name synonym)|uniprotkb:SCYB9B(gene name synonym) psi-mi:"MI:0892"(solid phase assay) Dyer et al. (2016) pubmed:27044744|imex:IM-25309 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-11739075|imex:IM-25309-22 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - intact:EBI-2871971(chain-parent) - - chain-seq-start:22|chain-seq-end:94 figure legend:4A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/05/05 2016/06/16 - rogid:+8aPUFAAe6mwzXVfmoNp0dGuTMM9606 - false biotin tag:?-? - - - psi-mi:"MI:0866"(tag visualisation) psi-mi:"MI:0866"(tag visualisation) chebi:"CHEBI:28304" uniprotkb:P13500-PRO_0000005146 intact:EBI-1379423 intact:EBI-11711396 psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long) psi-mi:p13500-pro_0000005146(display_long)|uniprotkb:HC11(gene name synonym)|uniprotkb:Monocyte chemoattractant protein 1(gene name synonym)|uniprotkb:Monocyte chemotactic and activating factor(gene name synonym)|uniprotkb:Monocyte chemotactic protein 1(gene name synonym)|uniprotkb:Monocyte secretory protein JE(gene name synonym)|uniprotkb:Small-inducible cytokine A2(gene name synonym)|uniprotkb:CCL2(gene name)|psi-mi:CCL2(display_short)|uniprotkb:MCP1(gene name synonym)|uniprotkb:SCYA2(gene name synonym) psi-mi:"MI:0892"(solid phase assay) Dyer et al. (2016) pubmed:27044744|imex:IM-25309 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-11739083|imex:IM-25309-23 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - intact:EBI-1034732(chain-parent) - - chain-seq-start:24|chain-seq-end:99 figure legend:4A-2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/05/05 2016/06/16 - rogid:GwGcN1L+gGK666Lo2ho6bOTl1IA9606 - false biotin tag:?-? - - - psi-mi:"MI:0866"(tag visualisation) psi-mi:"MI:0866"(tag visualisation) chebi:"CHEBI:28304" uniprotkb:O14625-PRO_0000005106 intact:EBI-1379423 intact:EBI-11711364 psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long) psi-mi:o14625-pro_0000005106(display_long)|uniprotkb:Beta-R1(gene name synonym)|uniprotkb:H174(gene name synonym)|uniprotkb:Interferon gamma-inducible protein 9(gene name synonym)|uniprotkb:Interferon-inducible T-cell alpha chemoattractant(gene name synonym)|uniprotkb:Small-inducible cytokine B11(gene name synonym)|uniprotkb:CXCL11(gene name)|psi-mi:CXCL11(display_short)|uniprotkb:ITAC(gene name synonym)|uniprotkb:SCYB11(gene name synonym)|uniprotkb:SCYB9B(gene name synonym) psi-mi:"MI:0892"(solid phase assay) Dyer et al. (2016) pubmed:27044744|imex:IM-25309 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-11739132|imex:IM-25309-18 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - intact:EBI-2871971(chain-parent) - - chain-seq-start:22|chain-seq-end:94 figure legend:4B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) ic50:168.0x10^-9(molar) 2016/05/05 2016/06/08 - rogid:+8aPUFAAe6mwzXVfmoNp0dGuTMM9606 - false biotin tag:?-? - - - psi-mi:"MI:0866"(tag visualisation) psi-mi:"MI:0866"(tag visualisation) uniprotkb:O14625-PRO_0000005106 uniprotkb:P98066 intact:EBI-11711364 intact:EBI-11700693|uniprotkb:Q53TI7|uniprotkb:Q8WWI9|ensembl:ENSP00000243347 psi-mi:o14625-pro_0000005106(display_long)|uniprotkb:Beta-R1(gene name synonym)|uniprotkb:H174(gene name synonym)|uniprotkb:Interferon gamma-inducible protein 9(gene name synonym)|uniprotkb:Interferon-inducible T-cell alpha chemoattractant(gene name synonym)|uniprotkb:Small-inducible cytokine B11(gene name synonym)|uniprotkb:CXCL11(gene name)|psi-mi:CXCL11(display_short)|uniprotkb:ITAC(gene name synonym)|uniprotkb:SCYB11(gene name synonym)|uniprotkb:SCYB9B(gene name synonym) psi-mi:tsg6_human(display_long)|uniprotkb:TSG6(gene name synonym)|uniprotkb:TNFAIP6(gene name)|psi-mi:TNFAIP6(display_short)|uniprotkb:Hyaluronate-binding protein(gene name synonym)|uniprotkb:TNF-stimulated gene 6 protein(gene name synonym)|uniprotkb:Tumor necrosis factor alpha-induced protein 6(gene name synonym) psi-mi:"MI:0892"(solid phase assay) Dyer et al. (2016) pubmed:27044744|imex:IM-25309 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-11739132|imex:IM-25309-18 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0941"(competitor) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2871971(chain-parent) refseq:NP_009046.2|ensembl:ENSG00000123610(gene)|ensembl:ENST00000243347(transcript)|go:"GO:0005540"(hyaluronic acid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006954"(inflammatory response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030728"(ovulation)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000538(Link)|interpro:IPR000859(CUB)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR035914|rcsb pdb:1O7B|rcsb pdb:1O7C|rcsb pdb:2N40|rcsb pdb:2PF5|rcsb pdb:2WNO|reactome:R-HSA-6798695 - chain-seq-start:22|chain-seq-end:94 - figure legend:4B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) ic50:168.0x10^-9(molar) 2016/05/05 2016/06/08 rogid:+8aPUFAAe6mwzXVfmoNp0dGuTMM9606 rogid:2Ea1tHjyixlxoJd7hef0CyUkjgk9606 - false - mutation:55-55,69-69,76-76|sufficient binding region:36-133 - - psi-mi:"MI:0866"(tag visualisation) psi-mi:"MI:0866"(tag visualisation) chebi:"CHEBI:28304" uniprotkb:P13500-PRO_0000005146 intact:EBI-1379423 intact:EBI-11711396 psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long) psi-mi:p13500-pro_0000005146(display_long)|uniprotkb:HC11(gene name synonym)|uniprotkb:Monocyte chemoattractant protein 1(gene name synonym)|uniprotkb:Monocyte chemotactic and activating factor(gene name synonym)|uniprotkb:Monocyte chemotactic protein 1(gene name synonym)|uniprotkb:Monocyte secretory protein JE(gene name synonym)|uniprotkb:Small-inducible cytokine A2(gene name synonym)|uniprotkb:CCL2(gene name)|psi-mi:CCL2(display_short)|uniprotkb:MCP1(gene name synonym)|uniprotkb:SCYA2(gene name synonym) psi-mi:"MI:0892"(solid phase assay) Dyer et al. (2016) pubmed:27044744|imex:IM-25309 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-11739150|imex:IM-25309-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - intact:EBI-1034732(chain-parent) - - chain-seq-start:24|chain-seq-end:99 figure legend:4B-2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) ic50:84.0x10^-9(molar) 2016/05/05 2016/06/16 - rogid:GwGcN1L+gGK666Lo2ho6bOTl1IA9606 - false biotin tag:?-? - - - psi-mi:"MI:0866"(tag visualisation) psi-mi:"MI:0866"(tag visualisation) uniprotkb:P13500-PRO_0000005146 uniprotkb:P98066 intact:EBI-11711396 intact:EBI-11700693|uniprotkb:Q53TI7|uniprotkb:Q8WWI9|ensembl:ENSP00000243347 psi-mi:p13500-pro_0000005146(display_long)|uniprotkb:HC11(gene name synonym)|uniprotkb:Monocyte chemoattractant protein 1(gene name synonym)|uniprotkb:Monocyte chemotactic and activating factor(gene name synonym)|uniprotkb:Monocyte chemotactic protein 1(gene name synonym)|uniprotkb:Monocyte secretory protein JE(gene name synonym)|uniprotkb:Small-inducible cytokine A2(gene name synonym)|uniprotkb:CCL2(gene name)|psi-mi:CCL2(display_short)|uniprotkb:MCP1(gene name synonym)|uniprotkb:SCYA2(gene name synonym) psi-mi:tsg6_human(display_long)|uniprotkb:TSG6(gene name synonym)|uniprotkb:TNFAIP6(gene name)|psi-mi:TNFAIP6(display_short)|uniprotkb:Hyaluronate-binding protein(gene name synonym)|uniprotkb:TNF-stimulated gene 6 protein(gene name synonym)|uniprotkb:Tumor necrosis factor alpha-induced protein 6(gene name synonym) psi-mi:"MI:0892"(solid phase assay) Dyer et al. (2016) pubmed:27044744|imex:IM-25309 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-11739150|imex:IM-25309-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0941"(competitor) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1034732(chain-parent) refseq:NP_009046.2|ensembl:ENSG00000123610(gene)|ensembl:ENST00000243347(transcript)|go:"GO:0005540"(hyaluronic acid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006954"(inflammatory response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030728"(ovulation)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000538(Link)|interpro:IPR000859(CUB)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR035914|rcsb pdb:1O7B|rcsb pdb:1O7C|rcsb pdb:2N40|rcsb pdb:2PF5|rcsb pdb:2WNO|reactome:R-HSA-6798695 - chain-seq-start:24|chain-seq-end:99 - figure legend:4B-2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) ic50:84.0x10^-9(molar) 2016/05/05 2016/06/16 rogid:GwGcN1L+gGK666Lo2ho6bOTl1IA9606 rogid:2Ea1tHjyixlxoJd7hef0CyUkjgk9606 - false - mutation:55-55,69-69,76-76|sufficient binding region:36-133 - - psi-mi:"MI:0866"(tag visualisation) psi-mi:"MI:0866"(tag visualisation) chebi:"CHEBI:28304" uniprotkb:Q99731-PRO_0000005214 intact:EBI-1379423 intact:EBI-11711510 psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long) psi-mi:q99731-pro_0000005214(display_long)|uniprotkb:CCL19(gene name)|psi-mi:CCL19(display_short)|uniprotkb:ELC(gene name synonym)|uniprotkb:MIP3B(gene name synonym)|uniprotkb:SCYA19(gene name synonym)|uniprotkb:Beta-chemokine exodus-3(gene name synonym)|uniprotkb:CK beta-11(gene name synonym)|uniprotkb:Epstein-Barr virus-induced molecule 1 ligand chemokine(gene name synonym)|uniprotkb:Macrophage inflammatory protein 3 beta(gene name synonym)|uniprotkb:Small-inducible cytokine A19(gene name synonym) psi-mi:"MI:0892"(solid phase assay) Dyer et al. (2016) pubmed:27044744|imex:IM-25309 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-11739164|imex:IM-25309-20 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - intact:EBI-11711434(chain-parent) - - chain-seq-start:22|chain-seq-end:98 figure legend:4C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) ic50:55.0x10^-9(molar) 2016/05/05 2016/06/16 - rogid:cx66QgixUzcWKwv9HGYLfGGfwU49606 - false biotin tag:?-? - - - psi-mi:"MI:0866"(tag visualisation) psi-mi:"MI:0866"(tag visualisation) uniprotkb:Q99731-PRO_0000005214 uniprotkb:P98066 intact:EBI-11711510 intact:EBI-11700693|uniprotkb:Q53TI7|uniprotkb:Q8WWI9|ensembl:ENSP00000243347 psi-mi:q99731-pro_0000005214(display_long)|uniprotkb:CCL19(gene name)|psi-mi:CCL19(display_short)|uniprotkb:ELC(gene name synonym)|uniprotkb:MIP3B(gene name synonym)|uniprotkb:SCYA19(gene name synonym)|uniprotkb:Beta-chemokine exodus-3(gene name synonym)|uniprotkb:CK beta-11(gene name synonym)|uniprotkb:Epstein-Barr virus-induced molecule 1 ligand chemokine(gene name synonym)|uniprotkb:Macrophage inflammatory protein 3 beta(gene name synonym)|uniprotkb:Small-inducible cytokine A19(gene name synonym) psi-mi:tsg6_human(display_long)|uniprotkb:TSG6(gene name synonym)|uniprotkb:TNFAIP6(gene name)|psi-mi:TNFAIP6(display_short)|uniprotkb:Hyaluronate-binding protein(gene name synonym)|uniprotkb:TNF-stimulated gene 6 protein(gene name synonym)|uniprotkb:Tumor necrosis factor alpha-induced protein 6(gene name synonym) psi-mi:"MI:0892"(solid phase assay) Dyer et al. (2016) pubmed:27044744|imex:IM-25309 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-11739164|imex:IM-25309-20 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0941"(competitor) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-11711434(chain-parent) refseq:NP_009046.2|ensembl:ENSG00000123610(gene)|ensembl:ENST00000243347(transcript)|go:"GO:0005540"(hyaluronic acid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006954"(inflammatory response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030728"(ovulation)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000538(Link)|interpro:IPR000859(CUB)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR035914|rcsb pdb:1O7B|rcsb pdb:1O7C|rcsb pdb:2N40|rcsb pdb:2PF5|rcsb pdb:2WNO|reactome:R-HSA-6798695 - chain-seq-start:22|chain-seq-end:98 - figure legend:4C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) ic50:55.0x10^-9(molar) 2016/05/05 2016/06/16 rogid:cx66QgixUzcWKwv9HGYLfGGfwU49606 rogid:2Ea1tHjyixlxoJd7hef0CyUkjgk9606 - false - mutation:55-55,69-69,76-76|sufficient binding region:36-133 - - psi-mi:"MI:0866"(tag visualisation) psi-mi:"MI:0866"(tag visualisation) uniprotkb:P80098-PRO_0000005183 uniprotkb:P98066 intact:EBI-11711410 intact:EBI-11700693|uniprotkb:Q53TI7|uniprotkb:Q8WWI9|ensembl:ENSP00000243347 psi-mi:p80098-pro_0000005183(display_long)|uniprotkb:CCL7(gene name)|psi-mi:CCL7(display_short)|uniprotkb:MCP3(gene name synonym)|uniprotkb:SCYA6(gene name synonym)|uniprotkb:SCYA7(gene name synonym)|uniprotkb:Monocyte chemoattractant protein 3(gene name synonym)|uniprotkb:Monocyte chemotactic protein 3(gene name synonym)|uniprotkb:NC28(gene name synonym)|uniprotkb:Small-inducible cytokine A7(gene name synonym) psi-mi:tsg6_human(display_long)|uniprotkb:TSG6(gene name synonym)|uniprotkb:TNFAIP6(gene name)|psi-mi:TNFAIP6(display_short)|uniprotkb:Hyaluronate-binding protein(gene name synonym)|uniprotkb:TNF-stimulated gene 6 protein(gene name synonym)|uniprotkb:Tumor necrosis factor alpha-induced protein 6(gene name synonym) psi-mi:"MI:0892"(solid phase assay) Dyer et al. (2016) pubmed:27044744|imex:IM-25309 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-11739178|imex:IM-25309-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0941"(competitor) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-718759(chain-parent) refseq:NP_009046.2|ensembl:ENSG00000123610(gene)|ensembl:ENST00000243347(transcript)|go:"GO:0005540"(hyaluronic acid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006954"(inflammatory response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030728"(ovulation)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000538(Link)|interpro:IPR000859(CUB)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR035914|rcsb pdb:1O7B|rcsb pdb:1O7C|rcsb pdb:2N40|rcsb pdb:2PF5|rcsb pdb:2WNO|reactome:R-HSA-6798695 - chain-seq-start:24|chain-seq-end:99 - figure legend:4C-2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) ic50:159.0x10^-9(molar) 2016/05/05 2016/06/08 rogid:dXg99QDACCGoX9nmdsytX7CZFZY9606 rogid:2Ea1tHjyixlxoJd7hef0CyUkjgk9606 - false - sufficient binding region:36-133|mutation:55-55,69-69,76-76 - - psi-mi:"MI:0866"(tag visualisation) psi-mi:"MI:0866"(tag visualisation) chebi:"CHEBI:28304" uniprotkb:P80098-PRO_0000005183 intact:EBI-1379423 intact:EBI-11711410 psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long) psi-mi:p80098-pro_0000005183(display_long)|uniprotkb:CCL7(gene name)|psi-mi:CCL7(display_short)|uniprotkb:MCP3(gene name synonym)|uniprotkb:SCYA6(gene name synonym)|uniprotkb:SCYA7(gene name synonym)|uniprotkb:Monocyte chemoattractant protein 3(gene name synonym)|uniprotkb:Monocyte chemotactic protein 3(gene name synonym)|uniprotkb:NC28(gene name synonym)|uniprotkb:Small-inducible cytokine A7(gene name synonym) psi-mi:"MI:0892"(solid phase assay) Dyer et al. (2016) pubmed:27044744|imex:IM-25309 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-11739178|imex:IM-25309-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - intact:EBI-718759(chain-parent) - - chain-seq-start:24|chain-seq-end:99 figure legend:4C-2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) ic50:159.0x10^-9(molar) 2016/05/05 2016/06/08 - rogid:dXg99QDACCGoX9nmdsytX7CZFZY9606 - false biotin tag:?-? - - - psi-mi:"MI:0866"(tag visualisation) psi-mi:"MI:0866"(tag visualisation)