#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O15078 uniprotkb:Q92834 intact:EBI-1811944|uniprotkb:Q1PSK5|uniprotkb:Q66GS8|uniprotkb:Q9H2G6|uniprotkb:Q9H6Q7|uniprotkb:Q9H8I0|ensembl:ENSP00000448012 intact:EBI-6558417|ensembl:ENSP00000343671|uniprotkb:B1ARN3|uniprotkb:E9PE28|uniprotkb:O00702|uniprotkb:O00737|uniprotkb:Q3KN84|uniprotkb:Q8N5T6|uniprotkb:Q93039|uniprotkb:Q9HD29|uniprotkb:Q9UMR1|intact:EBI-12703128|intact:EBI-16431503 psi-mi:ce290_human(display_long)|uniprotkb:CEP290(gene name)|psi-mi:CEP290(display_short)|uniprotkb:KIAA0373(gene name synonym)|uniprotkb:NPHP6(gene name synonym)|uniprotkb:Nephrocystin-6(gene name synonym)|uniprotkb:Tumor antigen se2-2(gene name synonym)|uniprotkb:Cancer/testis antigen 87(gene name synonym)|uniprotkb:BBS14(gene name synonym)|uniprotkb:Bardet-Biedl syndrome 14 protein(gene name synonym) psi-mi:rpgr_human(display_long)|uniprotkb:RPGR(gene name)|psi-mi:RPGR(display_short)|uniprotkb:RP3(gene name synonym)|uniprotkb:XLRP3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Rao et al. (2016) imex:IM-25506|pubmed:26936822 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-11709167|imex:IM-25506-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079390.3|dip:DIP-46541N|ensembl:ENSG00000198707(gene)|ensembl:ENST00000552810(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0030902"(hindbrain development)|go:"GO:0030916"(otic vesicle formation)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035580"(specific granule lumen)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048793"(pronephros development)|go:"GO:0060271"(cilium assembly)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0097711"(ciliary basal body-plasma membrane docking)|go:"GO:1905349"(ciliary transition zone assembly)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR026201|interpro:IPR032321|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-6798695|reactome:R-HSA-8854518 refseq:XP_016885199.1|ensembl:ENSG00000156313(gene)|ensembl:ENST00000339363(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0003723"(RNA binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007601"(visual perception)|go:"GO:0036064"(ciliary basal body)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042073"(intraciliary transport)|go:"GO:0050896"(response to stimulus)|go:"GO:0060271"(cilium assembly)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|rcsb pdb:4JHN|rcsb pdb:4JHP|rcsb pdb:4QAM|refseq:NP_000319.1|refseq:NP_001030025.1 - - - figure legend:5B-E|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2016/05/27 2016/05/27 rogid:89HbDVs4UVmzftFFLO/pHklTiUQ9606 rogid:yG3e/pDbkwML2e7J8BMMXY/EVPM9606 rigid:J0v1Q0a+rrDjTJwsX7viD/KenYw false sufficient binding region:1751-2050|sufficient binding region:2037-2479|green fluorescent protein tag:c-c sbp:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q6A078 uniprotkb:Q9JI70 intact:EBI-1811999|uniprotkb:Q8BIB8|ensembl:ENSMUSP00000151712 intact:EBI-6141664|uniprotkb:Q8BGQ3|ensembl:ENSMUSP00000028730|ensembl:ENSMUSP00000105716 psi-mi:ce290_mouse(display_long)|uniprotkb:Cep290(gene name)|psi-mi:Cep290(display_short)|uniprotkb:Kiaa0373(gene name synonym)|uniprotkb:Nphp6(gene name synonym)|uniprotkb:Nephrocystin-6(gene name synonym)|uniprotkb:Bardet-Biedl syndrome 14 protein homolog(gene name synonym) psi-mi:mkks_mouse(display_long)|uniprotkb:Mkks(gene name)|psi-mi:Mkks(display_short)|uniprotkb:Bbs6(gene name synonym)|uniprotkb:Protein Bbs6 homolog(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Rao et al. (2016) imex:IM-25506|pubmed:26936822 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-12515072|imex:IM-25506-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006513591.1|refseq:NP_666121.2|dip:DIP-46317N|ensembl:ENSMUSG00000019971(gene)|ensembl:ENSMUST00000219765(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001822"(kidney development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007507"(heart development)|go:"GO:0015031"(protein transport)|go:"GO:0030902"(hindbrain development)|go:"GO:0030916"(otic vesicle formation)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048793"(pronephros development)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060271"(cilium assembly)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0097711"(ciliary basal body-plasma membrane docking)|go:"GO:0120200"(rod photoreceptor outer segment)|go:"GO:0120205"(photoreceptor proximal connecting cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1905349"(ciliary transition zone assembly)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR026201|interpro:IPR032321|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-6798695|reactome:R-MMU-8854518 refseq:XP_011238023.1|refseq:NP_001135418.1|refseq:NP_067502.2|refseq:XP_006500033.1|dip:DIP-60355N|ensembl:ENSMUSG00000027274(gene)|ensembl:ENSMUST00000028730(transcript)|ensembl:ENSMUST00000110089(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0007286"(spermatid development)|go:"GO:0007608"(sensory perception of smell)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014824"(artery smooth muscle contraction)|go:"GO:0021756"(striatum development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0031514"(motile cilium)|go:"GO:0032502"(developmental process)|go:"GO:0033210"(leptin-mediated signaling pathway)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0035176"(social behavior)|go:"GO:0036064"(ciliary basal body)|go:"GO:0038108"(negative regulation of appetite by leptin-mediated signaling pathway)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042311"(vasodilation)|go:"GO:0044321"(response to leptin)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0045776"(negative regulation of blood pressure)|go:"GO:0046907"(intracellular transport)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051216"(cartilage development)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0060271"(cilium assembly)|go:"GO:0060296"(regulation of cilium beat frequency involved in ciliary motility)|go:"GO:0060324"(face development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1902636"(kinociliary basal body)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|interpro:IPR028790|reactome:R-MMU-5620922|go:"GO:0051131"(chaperone-mediated protein complex assembly) - - - figure legend:Supp 5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-retina)|taxid:10090(Mus musculus retina) - 2016/05/27 2016/09/06 rogid:6XYc7XLCqfq0g5xaB5l4amJnFT410090 rogid:KCXnWsXDpQspTj/VK66xrmEwaVw10090 rigid:dgMd+/nF1r+sD8bUc8xF1Kuhgvo false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)