#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B chebi:"CHEBI:28304" uniprotkb:P47992-PRO_0000005248 intact:EBI-1379423 intact:EBI-11740998 psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long) psi-mi:p47992-pro_0000005248(display_long)|uniprotkb:XCL1(gene name)|psi-mi:XCL1(display_short)|uniprotkb:LTN(gene name synonym)|uniprotkb:SCYC1(gene name synonym)|uniprotkb:ATAC(gene name synonym)|uniprotkb:C motif chemokine 1(gene name synonym)|uniprotkb:Cytokine SCM-1(gene name synonym)|uniprotkb:Lymphotaxin(gene name synonym)|uniprotkb:SCM-1-alpha(gene name synonym)|uniprotkb:Small-inducible cytokine C1(gene name synonym)|uniprotkb:XC chemokine ligand 1(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Fox et al. (2016) pubmed:26836755|imex:IM-26562 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-11740986|imex:IM-26562-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - intact:EBI-10209901(chain-parent) - - chain-seq-start:22|chain-seq-end:114 figure legend:3, 4A, Table 1|comment:"An unfolded/unstructured form of XCL1 showed substantially reduced binding; the CCO mutant has a double mutation of C11 and C48 to alanine which removes an intermolecular disulfide bond. A monomeric form of XCL1 also showed little binding;CC3 is an XCL1 double mutant (V21C, V59C) containing a second disulfide bond which restricts the protein to a monomeric form."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/05/11 2016/06/15 - rogid:rl3NoMLC3qfSPv7EEDDQnlLtWTc9606 - false - mutation increasing interaction strength:55-55|sufficient binding region:1-72|mutation decreasing interaction strength:70-70,55-55|mutation disrupting interaction strength:9-9,55-55|mutation decreasing interaction strength:18-18,55-55|mutation decreasing interaction strength:23-23,55-55|mutation decreasing interaction strength:35-35,55-55|mutation decreasing interaction strength:42-42,55-55|mutation disrupting interaction strength:25-25,55-55|mutation disrupting interaction strength:43-43,55-55|mutation with no effect:8-8,55-55|mutation disrupting interaction strength:21-21,59-59|mutation disrupting interaction strength:23-23,43-43,55-55|mutation with no effect:46-46,55-55|mutation with no effect:61-61,55-55|mutation disrupting interaction strength:11-11,48-48 - 2 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:28304" uniprotkb:P47992-PRO_0000005248 intact:EBI-1379423 intact:EBI-11740998 psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long) psi-mi:p47992-pro_0000005248(display_long)|uniprotkb:XCL1(gene name)|psi-mi:XCL1(display_short)|uniprotkb:LTN(gene name synonym)|uniprotkb:SCYC1(gene name synonym)|uniprotkb:ATAC(gene name synonym)|uniprotkb:C motif chemokine 1(gene name synonym)|uniprotkb:Cytokine SCM-1(gene name synonym)|uniprotkb:Lymphotaxin(gene name synonym)|uniprotkb:SCM-1-alpha(gene name synonym)|uniprotkb:Small-inducible cytokine C1(gene name synonym)|uniprotkb:XC chemokine ligand 1(gene name synonym) psi-mi:"MI:0107"(surface plasmon resonance) Fox et al. (2016) pubmed:26836755|imex:IM-26562 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-11741098|imex:IM-26562-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - intact:EBI-10209901(chain-parent) - - chain-seq-start:22|chain-seq-end:114 figure legend:Figure 5, Table 2|comment:"A monomeric form of XCL1 (CC3) also showed weaker binding ; CC3 is an XCL1 double mutant (V21C, V59C) containing a second disulfide bond which restricts the protein to a monomeric form."|kinetics:The Kd values obtained were calculated through both kinetic and steady state analysis. Values obtained by each method for each mutant vary considerably.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/05/11 2016/06/15 - rogid:rl3NoMLC3qfSPv7EEDDQnlLtWTc9606 - false - mutation with no effect:55-55|mutation:9-9,55-55|mutation:25-25,55-55|mutation decreasing interaction strength:21-21,59-59|mutation decreasing interaction strength:23-23,43-43,55-55 - 2 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:28304" uniprotkb:P47992-PRO_0000005248 intact:EBI-1379423 intact:EBI-11740998 psi-mi:heparin(display_short)|psi-mi:"CHEBI:28304"(display_long) psi-mi:p47992-pro_0000005248(display_long)|uniprotkb:XCL1(gene name)|psi-mi:XCL1(display_short)|uniprotkb:LTN(gene name synonym)|uniprotkb:SCYC1(gene name synonym)|uniprotkb:ATAC(gene name synonym)|uniprotkb:C motif chemokine 1(gene name synonym)|uniprotkb:Cytokine SCM-1(gene name synonym)|uniprotkb:Lymphotaxin(gene name synonym)|uniprotkb:SCM-1-alpha(gene name synonym)|uniprotkb:Small-inducible cytokine C1(gene name synonym)|uniprotkb:XC chemokine ligand 1(gene name synonym) psi-mi:"MI:0107"(surface plasmon resonance) Fox et al. (2016) pubmed:26836755|imex:IM-26562 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-11791741|imex:IM-26562-17 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - intact:EBI-10209901(chain-parent) - - chain-seq-start:22|chain-seq-end:114 figure legend:Figure 5i, Table 2|comment:"A monomeric form of XCL1 (CC3) also showed weaker binding ; CC3 is an XCL1 double mutant (V21C, V59C) containing a second disulfide bond which restricts the protein to a monomeric form."|kinetics:The Kd values obtained were calculated through both kinetic and steady state analysis. Values obtained by each method for each mutant vary considerably.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/05/11 2016/06/29 - rogid:rl3NoMLC3qfSPv7EEDDQnlLtWTc9606 - false - mutation:21-21,59-59 1 1 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:132213" uniprotkb:P47992-PRO_0000005248 intact:EBI-11783287 intact:EBI-11740998 psi-mi:heparin-dp4(display_short)|psi-mi:"CHEBI:132213"(display_long) psi-mi:p47992-pro_0000005248(display_long)|uniprotkb:XCL1(gene name)|psi-mi:XCL1(display_short)|uniprotkb:LTN(gene name synonym)|uniprotkb:SCYC1(gene name synonym)|uniprotkb:ATAC(gene name synonym)|uniprotkb:C motif chemokine 1(gene name synonym)|uniprotkb:Cytokine SCM-1(gene name synonym)|uniprotkb:Lymphotaxin(gene name synonym)|uniprotkb:SCM-1-alpha(gene name synonym)|uniprotkb:Small-inducible cytokine C1(gene name synonym)|uniprotkb:XC chemokine ligand 1(gene name synonym) psi-mi:"MI:0053"(fluorescence polarization spectroscopy) Fox et al. (2016) pubmed:26836755|imex:IM-26562 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-11783289|imex:IM-26562-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - intact:EBI-10209901(chain-parent) - - chain-seq-start:22|chain-seq-end:114 figure legend:Figure 6B,7|antagonist:sodium chloride|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:2.2x10^-6(molar) 2016/05/11 2016/06/20 - rogid:rl3NoMLC3qfSPv7EEDDQnlLtWTc9606 - false fluorescein label:?-? mutation:55-55|mutation decreasing interaction strength:23-23,43-43,55-55 - 2 psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) chebi:"CHEBI:132213" chebi:"CHEBI:132213" intact:EBI-11783287 intact:EBI-11783287 psi-mi:heparin-dp4(display_short)|psi-mi:"CHEBI:132213"(display_long) psi-mi:heparin-dp4(display_short)|psi-mi:"CHEBI:132213"(display_long) psi-mi:"MI:0053"(fluorescence polarization spectroscopy) Fox et al. (2016) pubmed:26836755|imex:IM-26562 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-11783325|imex:IM-26562-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0941"(competitor) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0328"(small molecule) - - - - - figure legend:Figure 6C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) ki:2.7x10^-6(molar)|ic50:7.4x10^-6(molar) 2016/05/11 2016/06/20 - - - false fluorescein label:?-? - - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) chebi:"CHEBI:132213" uniprotkb:P47992-PRO_0000005248 intact:EBI-11783287 intact:EBI-11740998 psi-mi:heparin-dp4(display_short)|psi-mi:"CHEBI:132213"(display_long) psi-mi:p47992-pro_0000005248(display_long)|uniprotkb:XCL1(gene name)|psi-mi:XCL1(display_short)|uniprotkb:LTN(gene name synonym)|uniprotkb:SCYC1(gene name synonym)|uniprotkb:ATAC(gene name synonym)|uniprotkb:C motif chemokine 1(gene name synonym)|uniprotkb:Cytokine SCM-1(gene name synonym)|uniprotkb:Lymphotaxin(gene name synonym)|uniprotkb:SCM-1-alpha(gene name synonym)|uniprotkb:Small-inducible cytokine C1(gene name synonym)|uniprotkb:XC chemokine ligand 1(gene name synonym) psi-mi:"MI:0053"(fluorescence polarization spectroscopy) Fox et al. (2016) pubmed:26836755|imex:IM-26562 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-11783325|imex:IM-26562-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - intact:EBI-10209901(chain-parent) - - chain-seq-start:22|chain-seq-end:114 figure legend:Figure 6C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) ki:2.7x10^-6(molar)|ic50:7.4x10^-6(molar) 2016/05/11 2016/06/20 - rogid:rl3NoMLC3qfSPv7EEDDQnlLtWTc9606 - false fluorescein label:?-? mutation:55-55 - 2 psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) chebi:"CHEBI:132215" chebi:"CHEBI:132213" intact:EBI-11783369 intact:EBI-11783287 psi-mi:dp8(display_short)|psi-mi:"CHEBI:132215"(display_long) psi-mi:heparin-dp4(display_short)|psi-mi:"CHEBI:132213"(display_long) psi-mi:"MI:0053"(fluorescence polarization spectroscopy) Fox et al. (2016) pubmed:26836755|imex:IM-26562 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-11783358|imex:IM-26562-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0941"(competitor) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0328"(small molecule) - - - - - figure legend:Figure 6C-2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) ki:0.9x10^-6(molar)|ic50:0.9x10^-6(molar) 2016/05/11 2016/06/20 - - - false - fluorescein label:?-? - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) chebi:"CHEBI:132215" uniprotkb:P47992-PRO_0000005248 intact:EBI-11783369 intact:EBI-11740998 psi-mi:dp8(display_short)|psi-mi:"CHEBI:132215"(display_long) psi-mi:p47992-pro_0000005248(display_long)|uniprotkb:XCL1(gene name)|psi-mi:XCL1(display_short)|uniprotkb:LTN(gene name synonym)|uniprotkb:SCYC1(gene name synonym)|uniprotkb:ATAC(gene name synonym)|uniprotkb:C motif chemokine 1(gene name synonym)|uniprotkb:Cytokine SCM-1(gene name synonym)|uniprotkb:Lymphotaxin(gene name synonym)|uniprotkb:SCM-1-alpha(gene name synonym)|uniprotkb:Small-inducible cytokine C1(gene name synonym)|uniprotkb:XC chemokine ligand 1(gene name synonym) psi-mi:"MI:0053"(fluorescence polarization spectroscopy) Fox et al. (2016) pubmed:26836755|imex:IM-26562 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-11783358|imex:IM-26562-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0941"(competitor) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - intact:EBI-10209901(chain-parent) - - chain-seq-start:22|chain-seq-end:114 figure legend:Figure 6C-2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) ki:0.9x10^-6(molar)|ic50:0.9x10^-6(molar) 2016/05/11 2016/06/20 - rogid:rl3NoMLC3qfSPv7EEDDQnlLtWTc9606 - false - mutation:55-55 - 2 psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) chebi:"CHEBI:132213" chebi:"CHEBI:132241" intact:EBI-11783287 intact:EBI-11783545 psi-mi:heparin-dp4(display_short)|psi-mi:"CHEBI:132213"(display_long) psi-mi:hs-10(display_short)|psi-mi:"CHEBI:132241"(display_long) psi-mi:"MI:0053"(fluorescence polarization spectroscopy) Fox et al. (2016) pubmed:26836755|imex:IM-26562 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-11783513|imex:IM-26562-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0941"(competitor) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0328"(small molecule) - - - - - figure legend:Figure 7|comment:An unsulfated heparan molecule and a less sulfated molecule were unable to compete for the binding sites occupied by the dp4 probe.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) ki:1.3x10^-6(molar)|ic50:1.4x10^-6(molar) 2016/05/11 2016/06/20 - - - false fluorescein label:?-? - - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) chebi:"CHEBI:132213" uniprotkb:P47992-PRO_0000005248 intact:EBI-11783287 intact:EBI-11740998 psi-mi:heparin-dp4(display_short)|psi-mi:"CHEBI:132213"(display_long) psi-mi:p47992-pro_0000005248(display_long)|uniprotkb:XCL1(gene name)|psi-mi:XCL1(display_short)|uniprotkb:LTN(gene name synonym)|uniprotkb:SCYC1(gene name synonym)|uniprotkb:ATAC(gene name synonym)|uniprotkb:C motif chemokine 1(gene name synonym)|uniprotkb:Cytokine SCM-1(gene name synonym)|uniprotkb:Lymphotaxin(gene name synonym)|uniprotkb:SCM-1-alpha(gene name synonym)|uniprotkb:Small-inducible cytokine C1(gene name synonym)|uniprotkb:XC chemokine ligand 1(gene name synonym) psi-mi:"MI:0053"(fluorescence polarization spectroscopy) Fox et al. (2016) pubmed:26836755|imex:IM-26562 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-11783513|imex:IM-26562-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - intact:EBI-10209901(chain-parent) - - chain-seq-start:22|chain-seq-end:114 figure legend:Figure 7|comment:An unsulfated heparan molecule and a less sulfated molecule were unable to compete for the binding sites occupied by the dp4 probe.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) ki:1.3x10^-6(molar)|ic50:1.4x10^-6(molar) 2016/05/11 2016/06/20 - rogid:rl3NoMLC3qfSPv7EEDDQnlLtWTc9606 - false fluorescein label:?-? mutation:55-55 - 2 psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) chebi:"CHEBI:132213" chebi:"CHEBI:132242" intact:EBI-11783287 intact:EBI-11783559 psi-mi:heparin-dp4(display_short)|psi-mi:"CHEBI:132213"(display_long) psi-mi:hs-14(display_short)|psi-mi:"CHEBI:132242"(display_long) psi-mi:"MI:0053"(fluorescence polarization spectroscopy) Fox et al. (2016) pubmed:26836755|imex:IM-26562 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-11783547|imex:IM-26562-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0941"(competitor) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0328"(small molecule) - - - - - figure legend:Figure 7-2|comment:An unsulfated heparan molecule and a less sulfated molecule were unable to compete for the binding sites occupied by the dp4 probe.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) ki:2.1x10^-6(molar)|ic50:2.2x10^-6(molar) 2016/05/11 2016/06/20 - - - false fluorescein label:?-? - - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) chebi:"CHEBI:132213" uniprotkb:P47992-PRO_0000005248 intact:EBI-11783287 intact:EBI-11740998 psi-mi:heparin-dp4(display_short)|psi-mi:"CHEBI:132213"(display_long) psi-mi:p47992-pro_0000005248(display_long)|uniprotkb:XCL1(gene name)|psi-mi:XCL1(display_short)|uniprotkb:LTN(gene name synonym)|uniprotkb:SCYC1(gene name synonym)|uniprotkb:ATAC(gene name synonym)|uniprotkb:C motif chemokine 1(gene name synonym)|uniprotkb:Cytokine SCM-1(gene name synonym)|uniprotkb:Lymphotaxin(gene name synonym)|uniprotkb:SCM-1-alpha(gene name synonym)|uniprotkb:Small-inducible cytokine C1(gene name synonym)|uniprotkb:XC chemokine ligand 1(gene name synonym) psi-mi:"MI:0053"(fluorescence polarization spectroscopy) Fox et al. (2016) pubmed:26836755|imex:IM-26562 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-11783547|imex:IM-26562-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - intact:EBI-10209901(chain-parent) - - chain-seq-start:22|chain-seq-end:114 figure legend:Figure 7-2|comment:An unsulfated heparan molecule and a less sulfated molecule were unable to compete for the binding sites occupied by the dp4 probe.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) ki:2.1x10^-6(molar)|ic50:2.2x10^-6(molar) 2016/05/11 2016/06/20 - rogid:rl3NoMLC3qfSPv7EEDDQnlLtWTc9606 - false fluorescein label:?-? mutation:55-55 - 2 psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) chebi:"CHEBI:132213" chebi:"CHEBI:132243" intact:EBI-11783287 intact:EBI-11783573 psi-mi:heparin-dp4(display_short)|psi-mi:"CHEBI:132213"(display_long) psi-mi:hs-15(display_short)|psi-mi:"CHEBI:132243"(display_long) psi-mi:"MI:0053"(fluorescence polarization spectroscopy) Fox et al. (2016) pubmed:26836755|imex:IM-26562 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-11783561|imex:IM-26562-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0941"(competitor) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0328"(small molecule) - - - - - figure legend:Figure 7-3|comment:An unsulfated heparan molecule and a less sulfated molecule were unable to compete for the binding sites occupied by the dp4 probe.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) ki:0.7x10^-6(molar)|ic50:0.7x10^-6(molar) 2016/05/11 2016/06/20 - - - false fluorescein label:?-? - - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) chebi:"CHEBI:132213" uniprotkb:P47992-PRO_0000005248 intact:EBI-11783287 intact:EBI-11740998 psi-mi:heparin-dp4(display_short)|psi-mi:"CHEBI:132213"(display_long) psi-mi:p47992-pro_0000005248(display_long)|uniprotkb:XCL1(gene name)|psi-mi:XCL1(display_short)|uniprotkb:LTN(gene name synonym)|uniprotkb:SCYC1(gene name synonym)|uniprotkb:ATAC(gene name synonym)|uniprotkb:C motif chemokine 1(gene name synonym)|uniprotkb:Cytokine SCM-1(gene name synonym)|uniprotkb:Lymphotaxin(gene name synonym)|uniprotkb:SCM-1-alpha(gene name synonym)|uniprotkb:Small-inducible cytokine C1(gene name synonym)|uniprotkb:XC chemokine ligand 1(gene name synonym) psi-mi:"MI:0053"(fluorescence polarization spectroscopy) Fox et al. (2016) pubmed:26836755|imex:IM-26562 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-11783561|imex:IM-26562-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - intact:EBI-10209901(chain-parent) - - chain-seq-start:22|chain-seq-end:114 figure legend:Figure 7-3|comment:An unsulfated heparan molecule and a less sulfated molecule were unable to compete for the binding sites occupied by the dp4 probe.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) ki:0.7x10^-6(molar)|ic50:0.7x10^-6(molar) 2016/05/11 2016/06/20 - rogid:rl3NoMLC3qfSPv7EEDDQnlLtWTc9606 - false fluorescein label:?-? mutation:55-55 - 2 psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence)