#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9XXD1 uniprotkb:P35602 intact:EBI-11598818|ensemblmetazoa:Y48A6B.6a.1|uniprotkb:Q6EUU0 intact:EBI-325082|uniprotkb:O02282|uniprotkb:Q1ZXR6|ensemblmetazoa:K11D2.3a.1|ensemblmetazoa:K11D2.3a.2 psi-mi:kvs4_caeel(display_long)|uniprotkb:kvs-4(gene name)|psi-mi:kvs-4(display_short)|uniprotkb:Y48A6B.6(orf name) psi-mi:ap1m_caeel(display_long)|uniprotkb:unc-101(gene name)|psi-mi:unc-101(display_short)|uniprotkb:K11D2.3(orf name)|uniprotkb:Mu1-I-adaptin(gene name synonym)|uniprotkb:Golgi adaptor AP-1 47 kDa protein(gene name synonym)|uniprotkb:HA1 47 kDa subunit(gene name synonym)|uniprotkb:Clathrin coat assembly protein AP47(gene name synonym)|uniprotkb:Clathrin coat-associated protein AP47(gene name synonym)|uniprotkb:Uncoordinated protein 101(gene name synonym)|uniprotkb:Clathrin assembly protein complex 1 mu-1-I medium chain(gene name synonym) psi-mi:"MI:0096"(pull down) Zhou et al. (2016) pubmed:26762178|imex:IM-25025 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-11598836|imex:IM-25025-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR027359|wormbase:Y48A6B.6b|interpro:IPR005821(Ion transport)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR003131(Potassium channel, voltage dependent, Kv, tetramerisation)|interpro:IPR028325|reactome:R-CEL-381676|ensemblmetazoa:WBGene00012967(gene)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0043204"(perikaryon)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0071805"(potassium ion transmembrane transport)|ensemblmetazoa:Y48A6B.6a.1(transcript)|refseq:NP_001022889.1|interpro:IPR003968(Potassium channel, voltage dependent, Kv)|interpro:IPR003971(Potassium channel, voltage dependent, Kv9)|refseq:NP_001022888.1|wormbase:Y48A6B.6a refseq:NP_001040675.1|refseq:NP_001040676.1|wormbase:K11D2.3a|wormbase:K11D2.3b|interpro:IPR022775|interpro:IPR001392(Clathrin adaptor, mu subunit)|interpro:IPR018240|interpro:IPR011012(Longin-like)|interpro:IPR028565|reactome:R-CEL-432720|ensemblmetazoa:K11D2.3a.1(transcript)|ensemblmetazoa:K11D2.3a.2(transcript)|ensemblmetazoa:WBGene00006829(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030121"(AP-1 adaptor complex)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030425"(dendrite)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045176"(apical protein localization)|go:"GO:0060271"(cilium assembly)|go:"GO:0097500"(receptor localization to non-motile cilium)|go:"GO:0040025"(vulval development)|reactome:R-CEL-432722|interpro:IPR036168|reactome:R-CEL-6798695 - - - figure legend:f5b f5c f6|comment:"Compared to that of KVS-4, significantly decreased pull-down of KVS-4ΔEQMIL (~ 40% down) and KVS-4ΔWNIIE (~ 45% down) by GST-UNC-101 were detected (Fig. 5C,F). Removal of both EQMIL and WNIIE motifs did not cause significantly weaker interactions than those caused by the individual loss of either of them (Fig. 5D,F), which is consistent with the idea that motifs within the bipartite signal function together as a unit. Next, we introduced the N-terminal WNIIE motif to the C-terminus of KVS-4ΔWNIIE and assayed its ability to recover the interaction between KVS-4 and UNC-101. Notably, KVS-4ΔWNIIE-WNIIE displayed a significant level of interaction with GST-UNC-101 (Fig. 5C,F)."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/02/17 2017/08/12 rogid:xcSpngPo2Hm/5vps5ovOsjak8As6239 rogid:5oPr82M39+SVVXT7xvmQ54RmfB46239 rigid:1BtciAr9uMwcGK4DEXVqWEg+nKs false ha tag:?-?|binding-associated region:496-500,227-231 binding-associated region:1-156|glutathione s tranferase tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)