#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P18177 uniprotkb:Q9NQS3 intact:EBI-8536569|uniprotkb:M4NW36|intact:MINT-2634250 intact:EBI-2826725|uniprotkb:Q8WVU4|uniprotkb:Q6NVZ3|uniprotkb:Q9Y412|uniprotkb:Q9BVA9|ensembl:ENSP00000418070|uniprotkb:E9PFR0|uniprotkb:Q8NC05 psi-mi:tcdb_clodi(display_long)|uniprotkb:tcdB(gene name)|psi-mi:tcdB(display_short)|uniprotkb:toxB(gene name synonym) psi-mi:nect3_human(display_long)|uniprotkb:NECTIN3(gene name)|psi-mi:NECTIN3(display_short)|uniprotkb:CDw113(gene name synonym)|uniprotkb:Nectin cell adhesion molecule 3(gene name synonym)|uniprotkb:PRR3(gene name synonym)|uniprotkb:PVRL3(gene name synonym)|uniprotkb:Poliovirus receptor-related protein 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Manse et al. (2015) imex:IM-24913|pubmed:26602083 taxid:1496(clodi)|taxid:1496(Clostridium difficile) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-11476595|imex:IM-24913-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_009902069.1|interpro:IPR020974|interpro:IPR018337|interpro:IPR024772|interpro:IPR024769|interpro:IPR024770|interpro:IPR029044|interpro:IPR038383|mint:P18177|go:"GO:0000822"(inositol hexakisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0008233"(peptidase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0008289"(lipid binding)|go:"GO:0016020"(membrane)|go:"GO:0016540"(protein autoprocessing)|go:"GO:0018243"(protein O-linked glycosylation via threonine)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0035251"(UDP-glucosyltransferase activity)|go:"GO:0044083"(modulation by symbiont of host Rho protein signal transduction)|go:"GO:0044164"(host cell cytosol)|go:"GO:0044174"(host cell endosome)|go:"GO:0044175"(host cell endosome membrane)|go:"GO:0046527"(glucosyltransferase activity)|go:"GO:0046789"(host cell surface receptor binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0090729"(toxin activity)|rcsb pdb:2BVL|rcsb pdb:2BVM|rcsb pdb:4NC2|rcsb pdb:4NP4|rcsb pdb:5UQM|rcsb pdb:5UQN|rcsb pdb:5UQT|rcsb pdb:6AR6|rcsb pdb:6C0B|rcsb pdb:6OQ5|rcsb pdb:6OQ6|rcsb pdb:6OQ7|rcsb pdb:6OQ8|rcsb pdb:7ML7 refseq:NP_001230215.1|refseq:NP_056295.1|ensembl:ENSG00000177707(gene)|ensembl:ENST00000485303(transcript)|go:"GO:0002089"(lens morphogenesis in camera-type eye)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007286"(spermatid development)|go:"GO:0009566"(fertilization)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043296"(apical junction complex)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0060042"(retina morphogenesis in camera-type eye)|go:"GO:0061951"(establishment of protein localization to plasma membrane)|reactome:R-HSA-420597|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:1902414"(protein localization to cell junction)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013162(CD80-like, immunoglobulin C2-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033319|interpro:IPR036179|rcsb pdb:4FOM|reactome:R-HSA-418990|refseq:NP_001230217.1|dip:DIP-41491N - comment:mint|function:Cytotoxin - figure legend:f4a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/01/11 2016/01/11 rogid:K4BbX+DMm7uUt0CrM1ONCFqaPwc1496 rogid:lzSScehKhxTPj0E6EmL+P+XXjB09606 rigid:r9T/zrn284qQ++/OLhL7k+h5G0g false flag tag:?-?|binding-associated region:1372-1493 his tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)