#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q5VY09 uniprotkb:Q5VY09 intact:EBI-1774000|uniprotkb:Q8WY68|uniprotkb:Q9NY49|uniprotkb:Q9NZP9|uniprotkb:B2RBV3|ensembl:ENSP00000356549 intact:EBI-1774000|uniprotkb:Q8WY68|uniprotkb:Q9NY49|uniprotkb:Q9NZP9|uniprotkb:B2RBV3|ensembl:ENSP00000356549 psi-mi:ier5_human(display_long)|uniprotkb:IER5(gene name)|psi-mi:IER5(display_short)|uniprotkb:PP4583(orf name)|uniprotkb:SBBI48(orf name) psi-mi:ier5_human(display_long)|uniprotkb:IER5(gene name)|psi-mi:IER5(display_short)|uniprotkb:PP4583(orf name)|uniprotkb:SBBI48(orf name) psi-mi:"MI:0096"(pull down) Kawabata et al. (2015) pubmed:26496226|imex:IM-24904 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-11475162|imex:IM-24904-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057629.2|ensembl:ENSG00000162783(gene)|ensembl:ENST00000367577(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1900036"(positive regulation of cellular response to heat)|interpro:IPR008653(Immediate early response) refseq:NP_057629.2|ensembl:ENSG00000162783(gene)|ensembl:ENST00000367577(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1900036"(positive regulation of cellular response to heat)|interpro:IPR008653(Immediate early response) - - - figure legend:f2b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2016/01/07 2016/01/07 rogid:D297tz5ThLd1cqyA1Fo/g5/nuN89606 rogid:D297tz5ThLd1cqyA1Fo/g5/nuN89606 rigid:X9iETXVx7jtH3e1CgYWay4/vXHY false ha tag:?-? his tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8N4C8-4 uniprotkb:Q5VY09 intact:EBI-11475194|ensembl:ENSP00000406487 intact:EBI-1774000|uniprotkb:Q8WY68|uniprotkb:Q9NY49|uniprotkb:Q9NZP9|uniprotkb:B2RBV3|ensembl:ENSP00000356549 psi-mi:q8n4c8-4(display_long)|uniprotkb:GCK family kinase MiNK(gene name synonym)|uniprotkb:MAPK/ERK kinase kinase kinase 6(gene name synonym)|uniprotkb:MINK1(gene name)|psi-mi:MINK1(display_short)|uniprotkb:B55(gene name synonym)|uniprotkb:MAP4K6(gene name synonym)|uniprotkb:MINK(gene name synonym)|uniprotkb:YSK2(gene name synonym)|uniprotkb:ZC3(gene name synonym)|uniprotkb:MINK-beta(isoform synonym)|uniprotkb:Misshapen/NIK-related kinase(gene name synonym)|uniprotkb:Mitogen-activated protein kinase kinase kinase kinase 6(gene name synonym) psi-mi:ier5_human(display_long)|uniprotkb:IER5(gene name)|psi-mi:IER5(display_short)|uniprotkb:PP4583(orf name)|uniprotkb:SBBI48(orf name) psi-mi:"MI:0096"(pull down) Kawabata et al. (2015) pubmed:26496226|imex:IM-24904 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-11475186|imex:IM-24904-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2133481(isoform-parent)|ensembl:ENSG00000141503(gene)|ensembl:ENST00000453408(transcript) refseq:NP_057629.2|ensembl:ENSG00000162783(gene)|ensembl:ENST00000367577(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1900036"(positive regulation of cellular response to heat)|interpro:IPR008653(Immediate early response) - - - figure legend:f3a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2016/01/07 2016/01/07 rogid:2NVUlAoQifTBp7b73B4E8OLSI6Q9606 rogid:D297tz5ThLd1cqyA1Fo/g5/nuN89606 rigid:vifAx12S+cENxd4+W9iebfBRMqU false ha tag:?-? his tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8N4C8-4 uniprotkb:Q5VY09 intact:EBI-11475194|ensembl:ENSP00000406487 intact:EBI-1774000|uniprotkb:Q8WY68|uniprotkb:Q9NY49|uniprotkb:Q9NZP9|uniprotkb:B2RBV3|ensembl:ENSP00000356549 psi-mi:q8n4c8-4(display_long)|uniprotkb:GCK family kinase MiNK(gene name synonym)|uniprotkb:MAPK/ERK kinase kinase kinase 6(gene name synonym)|uniprotkb:MINK1(gene name)|psi-mi:MINK1(display_short)|uniprotkb:B55(gene name synonym)|uniprotkb:MAP4K6(gene name synonym)|uniprotkb:MINK(gene name synonym)|uniprotkb:YSK2(gene name synonym)|uniprotkb:ZC3(gene name synonym)|uniprotkb:MINK-beta(isoform synonym)|uniprotkb:Misshapen/NIK-related kinase(gene name synonym)|uniprotkb:Mitogen-activated protein kinase kinase kinase kinase 6(gene name synonym) psi-mi:ier5_human(display_long)|uniprotkb:IER5(gene name)|psi-mi:IER5(display_short)|uniprotkb:PP4583(orf name)|uniprotkb:SBBI48(orf name) psi-mi:"MI:0096"(pull down) Kawabata et al. (2015) pubmed:26496226|imex:IM-24904 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-11475206|imex:IM-24904-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2133481(isoform-parent)|ensembl:ENSG00000141503(gene)|ensembl:ENST00000453408(transcript) refseq:NP_057629.2|ensembl:ENSG00000162783(gene)|ensembl:ENST00000367577(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1900036"(positive regulation of cellular response to heat)|interpro:IPR008653(Immediate early response) - - - figure legend:f3c|comment:"The GST- 49C fusion failed to retain B55b-HA, suggesting that the N-terminal IER2 homology region is necessary for the binding. The GST-N246 fusion lacking the C-terminal 81 amino acids exhibited reduced binding ability relative to GST-FL; however, the C-terminal region itself failed to retain B55b-HA (GST-234C). The GST-ID fusion lacking the internal region of IER5 efficiently bound to B55b-HA. Therefore, binding to B55b is mediated by both the N-terminal and C-terminal regions of IER5, where the C-terminal region enhances the binding only in the presence of the N-terminal region"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2016/01/07 2016/01/07 rogid:2NVUlAoQifTBp7b73B4E8OLSI6Q9606 rogid:D297tz5ThLd1cqyA1Fo/g5/nuN89606 rigid:vifAx12S+cENxd4+W9iebfBRMqU false ha tag:?-? binding-associated region:1-156,237-327|glutathione s tranferase tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P67775 uniprotkb:Q5VY09 intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197 intact:EBI-1774000|uniprotkb:Q8WY68|uniprotkb:Q9NY49|uniprotkb:Q9NZP9|uniprotkb:B2RBV3|ensembl:ENSP00000356549 psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym) psi-mi:ier5_human(display_long)|uniprotkb:IER5(gene name)|psi-mi:IER5(display_short)|uniprotkb:PP4583(orf name)|uniprotkb:SBBI48(orf name) psi-mi:"MI:0096"(pull down) Kawabata et al. (2015) pubmed:26496226|imex:IM-24904 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-11475274|imex:IM-24904-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N refseq:NP_057629.2|ensembl:ENSG00000162783(gene)|ensembl:ENST00000367577(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1900036"(positive regulation of cellular response to heat)|interpro:IPR008653(Immediate early response) - - - figure legend:f3d|comment:"The GST- 49C fusion failed to retain B55b-HA, suggesting that the N-terminal IER2 homology region is necessary for the binding. The GST-N246 fusion lacking the C-terminal 81 amino acids exhibited reduced binding ability relative to GST-FL; however, the C-terminal region itself failed to retain B55b-HA (GST-234C). The GST-ID fusion lacking the internal region of IER5 efficiently bound to B55b-HA. Therefore, binding to B55b is mediated by both the N-terminal and C-terminal regions of IER5, where the C-terminal region enhances the binding only in the presence of the N-terminal region"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2016/01/07 2016/01/07 rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606 rogid:D297tz5ThLd1cqyA1Fo/g5/nuN89606 rigid:u+Dt0v11nRGWd9YMbFLfXBDQIe8 false - glutathione s tranferase tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P23443 uniprotkb:Q5VY09 intact:EBI-1775921|uniprotkb:B2R779|uniprotkb:B4DTG1|uniprotkb:F6UYM1|intact:EBI-11107861|uniprotkb:B4DLT4|uniprotkb:E7ESB8|uniprotkb:Q7Z721|ensembl:ENSP00000225577 intact:EBI-1774000|uniprotkb:Q8WY68|uniprotkb:Q9NY49|uniprotkb:Q9NZP9|uniprotkb:B2RBV3|ensembl:ENSP00000356549 psi-mi:ks6b1_human(display_long)|uniprotkb:RPS6KB1(gene name)|psi-mi:RPS6KB1(display_short)|uniprotkb:STK14A(gene name synonym)|uniprotkb:Ribosomal protein S6 kinase I(gene name synonym)|uniprotkb:p70 ribosomal S6 kinase alpha(gene name synonym)|uniprotkb:70 kDa ribosomal protein S6 kinase 1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 14A(gene name synonym) psi-mi:ier5_human(display_long)|uniprotkb:IER5(gene name)|psi-mi:IER5(display_short)|uniprotkb:PP4583(orf name)|uniprotkb:SBBI48(orf name) psi-mi:"MI:0096"(pull down) Kawabata et al. (2015) pubmed:26496226|imex:IM-24904 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-11475335|imex:IM-24904-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003152.1|refseq:NP_001258989.1|refseq:NP_001258971.1|refseq:NP_001258972.1|refseq:NP_001258973.1|dip:DIP-29986N|ensembl:ENSG00000108443(gene)|ensembl:ENST00000225577(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004711"(ribosomal protein S6 kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0031929"(TOR signaling)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0043005"(neuron projection)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044539"(long-chain fatty acid import into cell)|go:"GO:0045202"(synapse)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016238(Ribosomal protein S6 kinase)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|mint:P23443|rcsb pdb:3A60|rcsb pdb:3A61|rcsb pdb:3A62|rcsb pdb:3WE4|rcsb pdb:3WF5|rcsb pdb:3WF6|rcsb pdb:3WF7|rcsb pdb:3WF8|rcsb pdb:3WF9|rcsb pdb:4L3J|rcsb pdb:4L3L|rcsb pdb:4L42|rcsb pdb:4L43|rcsb pdb:4L44|rcsb pdb:4L45|rcsb pdb:4L46|rcsb pdb:4RLO|rcsb pdb:4RLP|rcsb pdb:5WBH|rcsb pdb:5WBK|reactome:R-HSA-166208 refseq:NP_057629.2|ensembl:ENSG00000162783(gene)|ensembl:ENST00000367577(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1900036"(positive regulation of cellular response to heat)|interpro:IPR008653(Immediate early response) - - - figure legend:f4d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2016/01/07 2016/01/11 rogid:rEFXLi6QTM8wdG7FNx1er6EzPFM9606 rogid:D297tz5ThLd1cqyA1Fo/g5/nuN89606 rigid:M9nm0QdcDwGYfv2SUEmVxExwKas false ha tag:?-? his tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P23443 uniprotkb:Q5VY09 intact:EBI-1775921|uniprotkb:B2R779|uniprotkb:B4DTG1|uniprotkb:F6UYM1|intact:EBI-11107861|uniprotkb:B4DLT4|uniprotkb:E7ESB8|uniprotkb:Q7Z721|ensembl:ENSP00000225577 intact:EBI-1774000|uniprotkb:Q8WY68|uniprotkb:Q9NY49|uniprotkb:Q9NZP9|uniprotkb:B2RBV3|ensembl:ENSP00000356549 psi-mi:ks6b1_human(display_long)|uniprotkb:RPS6KB1(gene name)|psi-mi:RPS6KB1(display_short)|uniprotkb:STK14A(gene name synonym)|uniprotkb:Ribosomal protein S6 kinase I(gene name synonym)|uniprotkb:p70 ribosomal S6 kinase alpha(gene name synonym)|uniprotkb:70 kDa ribosomal protein S6 kinase 1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 14A(gene name synonym) psi-mi:ier5_human(display_long)|uniprotkb:IER5(gene name)|psi-mi:IER5(display_short)|uniprotkb:PP4583(orf name)|uniprotkb:SBBI48(orf name) psi-mi:"MI:0096"(pull down) Kawabata et al. (2015) pubmed:26496226|imex:IM-24904 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-11475343|imex:IM-24904-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003152.1|refseq:NP_001258989.1|refseq:NP_001258971.1|refseq:NP_001258972.1|refseq:NP_001258973.1|dip:DIP-29986N|ensembl:ENSG00000108443(gene)|ensembl:ENST00000225577(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004711"(ribosomal protein S6 kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0031929"(TOR signaling)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0043005"(neuron projection)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044539"(long-chain fatty acid import into cell)|go:"GO:0045202"(synapse)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016238(Ribosomal protein S6 kinase)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|mint:P23443|rcsb pdb:3A60|rcsb pdb:3A61|rcsb pdb:3A62|rcsb pdb:3WE4|rcsb pdb:3WF5|rcsb pdb:3WF6|rcsb pdb:3WF7|rcsb pdb:3WF8|rcsb pdb:3WF9|rcsb pdb:4L3J|rcsb pdb:4L3L|rcsb pdb:4L42|rcsb pdb:4L43|rcsb pdb:4L44|rcsb pdb:4L45|rcsb pdb:4L46|rcsb pdb:4RLO|rcsb pdb:4RLP|rcsb pdb:5WBH|rcsb pdb:5WBK|reactome:R-HSA-166208 refseq:NP_057629.2|ensembl:ENSG00000162783(gene)|ensembl:ENST00000367577(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1900036"(positive regulation of cellular response to heat)|interpro:IPR008653(Immediate early response) - - - figure legend:f4e|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2016/01/07 2016/01/11 rogid:rEFXLi6QTM8wdG7FNx1er6EzPFM9606 rogid:D297tz5ThLd1cqyA1Fo/g5/nuN89606 rigid:M9nm0QdcDwGYfv2SUEmVxExwKas false ha tag:?-? binding-associated region:1-234|glutathione s tranferase tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q00613 uniprotkb:Q5VY09 intact:EBI-719620|uniprotkb:A8MW26|uniprotkb:Q53XT4|uniprotkb:A8K4L0|ensembl:ENSP00000431512|ensembl:ENSP00000493830 intact:EBI-1774000|uniprotkb:Q8WY68|uniprotkb:Q9NY49|uniprotkb:Q9NZP9|uniprotkb:B2RBV3|ensembl:ENSP00000356549 psi-mi:hsf1_human(display_long)|uniprotkb:Heat shock transcription factor 1(gene name synonym)|uniprotkb:HSF1(gene name)|psi-mi:HSF1(display_short)|uniprotkb:HSTF1(gene name synonym) psi-mi:ier5_human(display_long)|uniprotkb:IER5(gene name)|psi-mi:IER5(display_short)|uniprotkb:PP4583(orf name)|uniprotkb:SBBI48(orf name) psi-mi:"MI:0096"(pull down) Kawabata et al. (2015) pubmed:26496226|imex:IM-24904 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-11475359|imex:IM-24904-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005517.1|go:"GO:0006397"(mRNA processing)|go:"GO:0006952"(defense response)|go:"GO:0007584"(response to nutrient)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009299"(mRNA transcription)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0014823"(response to activity)|go:"GO:0016605"(PML body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0033574"(response to testosterone)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034622"|go:"GO:0035865"(cellular response to potassium ion)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042802"(identical protein binding)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045651"(positive regulation of macrophage differentiation)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051028"(mRNA transport)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061408"(positive regulation of transcription from RNA polymerase II promoter in response to heat stress)|go:"GO:0061770"(translation elongation factor binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071280"(cellular response to copper ion)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0072738"(cellular response to diamide)|go:"GO:0090084"(negative regulation of inclusion body assembly)|go:"GO:0090261"(positive regulation of inclusion body assembly)|go:"GO:0097165"(nuclear stress granule)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0097677"(STAT family protein binding)|go:"GO:0098847"(sequence-specific single stranded DNA binding)|go:"GO:0101031"(chaperone complex)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1900034"(regulation of cellular response to heat)|go:"GO:1900365"(positive regulation of mRNA polyadenylation)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902512"(positive regulation of apoptotic DNA fragmentation)|go:"GO:1903936"(cellular response to sodium arsenite)|go:"GO:1904385"(cellular response to angiotensin)|go:"GO:1904528"(positive regulation of microtubule binding)|go:"GO:1904843"(cellular response to nitroglycerin)|go:"GO:1904845"(cellular response to L-glutamine)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:1990910"(response to hypobaric hypoxia)|go:"GO:1990911"(response to psychosocial stress)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000232("Heat shock factor (HSF)-type, DNA-binding")|interpro:IPR010542(Vertebrate heat shock transcription factor)|interpro:IPR027725|interpro:IPR036388|interpro:IPR036390|mint:Q00613|rcsb pdb:2LDU|rcsb pdb:5D5U|rcsb pdb:5D5V|rcsb pdb:5HDG|rcsb pdb:5HDN|reactome:R-HSA-3371453|reactome:R-HSA-3371511|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-9646399|ensembl:ENSG00000185122(gene)|ensembl:ENSG00000284774(gene)|ensembl:ENST00000528838(transcript)|ensembl:ENST00000646252(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000776"(kinetochore)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001162"(RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|refseq:XP_016868866.1|dip:DIP-35670N refseq:NP_057629.2|ensembl:ENSG00000162783(gene)|ensembl:ENST00000367577(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1900036"(positive regulation of cellular response to heat)|interpro:IPR008653(Immediate early response) - - - figure legend:f5c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2016/01/07 2016/01/07 rogid:8Kc0CyLMImN2fpNco/AAIbJk+6k9606 rogid:D297tz5ThLd1cqyA1Fo/g5/nuN89606 rigid:Wr0AHzTK5VwDemxFDa9d9ccoZO8 false - his tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q00613 uniprotkb:Q5VY09 intact:EBI-719620|uniprotkb:A8MW26|uniprotkb:Q53XT4|uniprotkb:A8K4L0|ensembl:ENSP00000431512|ensembl:ENSP00000493830 intact:EBI-1774000|uniprotkb:Q8WY68|uniprotkb:Q9NY49|uniprotkb:Q9NZP9|uniprotkb:B2RBV3|ensembl:ENSP00000356549 psi-mi:hsf1_human(display_long)|uniprotkb:Heat shock transcription factor 1(gene name synonym)|uniprotkb:HSF1(gene name)|psi-mi:HSF1(display_short)|uniprotkb:HSTF1(gene name synonym) psi-mi:ier5_human(display_long)|uniprotkb:IER5(gene name)|psi-mi:IER5(display_short)|uniprotkb:PP4583(orf name)|uniprotkb:SBBI48(orf name) psi-mi:"MI:0096"(pull down) Kawabata et al. (2015) pubmed:26496226|imex:IM-24904 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-11475367|imex:IM-24904-17 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005517.1|go:"GO:0006397"(mRNA processing)|go:"GO:0006952"(defense response)|go:"GO:0007584"(response to nutrient)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009299"(mRNA transcription)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0014823"(response to activity)|go:"GO:0016605"(PML body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0033574"(response to testosterone)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034622"|go:"GO:0035865"(cellular response to potassium ion)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042802"(identical protein binding)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045651"(positive regulation of macrophage differentiation)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051028"(mRNA transport)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061408"(positive regulation of transcription from RNA polymerase II promoter in response to heat stress)|go:"GO:0061770"(translation elongation factor binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071280"(cellular response to copper ion)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0072738"(cellular response to diamide)|go:"GO:0090084"(negative regulation of inclusion body assembly)|go:"GO:0090261"(positive regulation of inclusion body assembly)|go:"GO:0097165"(nuclear stress granule)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0097677"(STAT family protein binding)|go:"GO:0098847"(sequence-specific single stranded DNA binding)|go:"GO:0101031"(chaperone complex)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1900034"(regulation of cellular response to heat)|go:"GO:1900365"(positive regulation of mRNA polyadenylation)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902512"(positive regulation of apoptotic DNA fragmentation)|go:"GO:1903936"(cellular response to sodium arsenite)|go:"GO:1904385"(cellular response to angiotensin)|go:"GO:1904528"(positive regulation of microtubule binding)|go:"GO:1904843"(cellular response to nitroglycerin)|go:"GO:1904845"(cellular response to L-glutamine)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:1990910"(response to hypobaric hypoxia)|go:"GO:1990911"(response to psychosocial stress)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000232("Heat shock factor (HSF)-type, DNA-binding")|interpro:IPR010542(Vertebrate heat shock transcription factor)|interpro:IPR027725|interpro:IPR036388|interpro:IPR036390|mint:Q00613|rcsb pdb:2LDU|rcsb pdb:5D5U|rcsb pdb:5D5V|rcsb pdb:5HDG|rcsb pdb:5HDN|reactome:R-HSA-3371453|reactome:R-HSA-3371511|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-9646399|ensembl:ENSG00000185122(gene)|ensembl:ENSG00000284774(gene)|ensembl:ENST00000528838(transcript)|ensembl:ENST00000646252(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000776"(kinetochore)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001162"(RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|refseq:XP_016868866.1|dip:DIP-35670N refseq:NP_057629.2|ensembl:ENSG00000162783(gene)|ensembl:ENST00000367577(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1900036"(positive regulation of cellular response to heat)|interpro:IPR008653(Immediate early response) - - - figure legend:f5d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2016/01/07 2016/01/07 rogid:8Kc0CyLMImN2fpNco/AAIbJk+6k9606 rogid:D297tz5ThLd1cqyA1Fo/g5/nuN89606 rigid:Wr0AHzTK5VwDemxFDa9d9ccoZO8 false - binding-associated region:1-246|glutathione s tranferase tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q5VY09 uniprotkb:Q5VY09 intact:EBI-1774000|uniprotkb:Q8WY68|uniprotkb:Q9NY49|uniprotkb:Q9NZP9|uniprotkb:B2RBV3|ensembl:ENSP00000356549 intact:EBI-1774000|uniprotkb:Q8WY68|uniprotkb:Q9NY49|uniprotkb:Q9NZP9|uniprotkb:B2RBV3|ensembl:ENSP00000356549 psi-mi:ier5_human(display_long)|uniprotkb:IER5(gene name)|psi-mi:IER5(display_short)|uniprotkb:PP4583(orf name)|uniprotkb:SBBI48(orf name) psi-mi:ier5_human(display_long)|uniprotkb:IER5(gene name)|psi-mi:IER5(display_short)|uniprotkb:PP4583(orf name)|uniprotkb:SBBI48(orf name) psi-mi:"MI:0096"(pull down) Kawabata et al. (2015) pubmed:26496226|imex:IM-24904 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-11475170|imex:IM-24904-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057629.2|ensembl:ENSG00000162783(gene)|ensembl:ENST00000367577(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1900036"(positive regulation of cellular response to heat)|interpro:IPR008653(Immediate early response) refseq:NP_057629.2|ensembl:ENSG00000162783(gene)|ensembl:ENST00000367577(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1900036"(positive regulation of cellular response to heat)|interpro:IPR008653(Immediate early response) - - - figure legend:f2c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2016/01/07 2016/01/07 rogid:D297tz5ThLd1cqyA1Fo/g5/nuN89606 rogid:D297tz5ThLd1cqyA1Fo/g5/nuN89606 rigid:X9iETXVx7jtH3e1CgYWay4/vXHY false binding-associated region:1-156 his tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)