#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P51955 uniprotkb:Q5T7B8 intact:EBI-633182|uniprotkb:Q53FD6|uniprotkb:Q5VXZ1|intact:EBI-4311380|uniprotkb:Q5I1Z9|uniprotkb:Q6NZX8|uniprotkb:Q7Z634|uniprotkb:Q86XH2|uniprotkb:Q96QN9|ensembl:ENSP00000355966 intact:EBI-2556811|uniprotkb:Q6ZUZ2|uniprotkb:Q86XZ0|uniprotkb:Q5T7B7|uniprotkb:Q2TB93|uniprotkb:Q5T7B5|uniprotkb:Q9NV43|uniprotkb:Q6ZU97|ensembl:ENSP00000384433 psi-mi:nek2_human(display_long)|uniprotkb:NEK2A(gene name synonym)|uniprotkb:NimA-like protein kinase 1(gene name synonym)|uniprotkb:HSPK 21(gene name synonym)|uniprotkb:NEK2(gene name)|psi-mi:NEK2(display_short)|uniprotkb:NLK1(gene name synonym)|uniprotkb:Never in mitosis A-related kinase 2(gene name synonym) psi-mi:kif24_human(display_long)|uniprotkb:C9orf48(gene name synonym)|uniprotkb:KIF24(gene name)|psi-mi:KIF24(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kim et al. (2015) pubmed:26290419|imex:IM-25477 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-11810095|imex:IM-25477-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001191111.1|refseq:NP_001191112.1|refseq:NP_002488.1|ensembl:ENSG00000117650(gene)|ensembl:ENST00000366999(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000922"(spindle pole)|go:"GO:0001824"(blastocyst development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030496"(midbody)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0046602"(regulation of mitotic centrosome separation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051299"(centrosome separation)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0051988"(regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903126"(negative regulation of centriole-centriole cohesion)|go:"GO:1904355"(positive regulation of telomere capping)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|mint:P51955|rcsb pdb:2JAV|rcsb pdb:2W5A|rcsb pdb:2W5B|rcsb pdb:2W5H|rcsb pdb:2WQO|rcsb pdb:2XK3|rcsb pdb:2XK4|rcsb pdb:2XK6|rcsb pdb:2XK7|rcsb pdb:2XK8|rcsb pdb:2XKC|rcsb pdb:2XKD|rcsb pdb:2XKE|rcsb pdb:2XKF|rcsb pdb:2XNM|rcsb pdb:2XNN|rcsb pdb:2XNO|rcsb pdb:2XNP|rcsb pdb:4A4X|rcsb pdb:4AFE|rcsb pdb:5M51|rcsb pdb:5M53|rcsb pdb:5M55|rcsb pdb:5M57|rcsb pdb:6SGD|rcsb pdb:6SGH|rcsb pdb:6SGI|rcsb pdb:6SGK|rcsb pdb:6SK9|rcsb pdb:6TM5|reactome:R-HSA-179409|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:XP_005273204.1 refseq:XP_011516165.1|ensembl:ENSG00000186638(gene)|ensembl:ENST00000402558(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007019"(microtubule depolymerization)|go:"GO:0008017"(microtubule binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0060271"(cilium assembly)|go:"GO:1990939"|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR019821|interpro:IPR027417|interpro:IPR036961|reactome:R-HSA-5620912|refseq:NP_919289.2|refseq:XP_016870186.1 - - - figure legend:1a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2016/07/07 2016/07/07 rogid:7iozc82+IF+sGyerzvp571Uc1RM9606 rogid:ZaT+RA4urWXtHuUy20eBs/X6hp89606 rigid:c6zuXzeScWBYCi685KvE9fS+1cc false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P51955 uniprotkb:Q5T7B8 intact:EBI-633182|uniprotkb:Q53FD6|uniprotkb:Q5VXZ1|intact:EBI-4311380|uniprotkb:Q5I1Z9|uniprotkb:Q6NZX8|uniprotkb:Q7Z634|uniprotkb:Q86XH2|uniprotkb:Q96QN9|ensembl:ENSP00000355966 intact:EBI-2556811|uniprotkb:Q6ZUZ2|uniprotkb:Q86XZ0|uniprotkb:Q5T7B7|uniprotkb:Q2TB93|uniprotkb:Q5T7B5|uniprotkb:Q9NV43|uniprotkb:Q6ZU97|ensembl:ENSP00000384433 psi-mi:nek2_human(display_long)|uniprotkb:NEK2A(gene name synonym)|uniprotkb:NimA-like protein kinase 1(gene name synonym)|uniprotkb:HSPK 21(gene name synonym)|uniprotkb:NEK2(gene name)|psi-mi:NEK2(display_short)|uniprotkb:NLK1(gene name synonym)|uniprotkb:Never in mitosis A-related kinase 2(gene name synonym) psi-mi:kif24_human(display_long)|uniprotkb:C9orf48(gene name synonym)|uniprotkb:KIF24(gene name)|psi-mi:KIF24(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kim et al. (2015) pubmed:26290419|imex:IM-25477 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-11810099|imex:IM-25477-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001191111.1|refseq:NP_001191112.1|refseq:NP_002488.1|ensembl:ENSG00000117650(gene)|ensembl:ENST00000366999(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000922"(spindle pole)|go:"GO:0001824"(blastocyst development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030496"(midbody)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0046602"(regulation of mitotic centrosome separation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051299"(centrosome separation)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0051988"(regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903126"(negative regulation of centriole-centriole cohesion)|go:"GO:1904355"(positive regulation of telomere capping)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|mint:P51955|rcsb pdb:2JAV|rcsb pdb:2W5A|rcsb pdb:2W5B|rcsb pdb:2W5H|rcsb pdb:2WQO|rcsb pdb:2XK3|rcsb pdb:2XK4|rcsb pdb:2XK6|rcsb pdb:2XK7|rcsb pdb:2XK8|rcsb pdb:2XKC|rcsb pdb:2XKD|rcsb pdb:2XKE|rcsb pdb:2XKF|rcsb pdb:2XNM|rcsb pdb:2XNN|rcsb pdb:2XNO|rcsb pdb:2XNP|rcsb pdb:4A4X|rcsb pdb:4AFE|rcsb pdb:5M51|rcsb pdb:5M53|rcsb pdb:5M55|rcsb pdb:5M57|rcsb pdb:6SGD|rcsb pdb:6SGH|rcsb pdb:6SGI|rcsb pdb:6SGK|rcsb pdb:6SK9|rcsb pdb:6TM5|reactome:R-HSA-179409|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:XP_005273204.1 refseq:XP_011516165.1|ensembl:ENSG00000186638(gene)|ensembl:ENST00000402558(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007019"(microtubule depolymerization)|go:"GO:0008017"(microtubule binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0060271"(cilium assembly)|go:"GO:1990939"|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR019821|interpro:IPR027417|interpro:IPR036961|reactome:R-HSA-5620912|refseq:NP_919289.2|refseq:XP_016870186.1 - - - figure legend:1a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2016/07/07 2016/07/07 rogid:7iozc82+IF+sGyerzvp571Uc1RM9606 rogid:ZaT+RA4urWXtHuUy20eBs/X6hp89606 rigid:c6zuXzeScWBYCi685KvE9fS+1cc false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P51955 uniprotkb:Q5T7B8 intact:EBI-633182|uniprotkb:Q53FD6|uniprotkb:Q5VXZ1|intact:EBI-4311380|uniprotkb:Q5I1Z9|uniprotkb:Q6NZX8|uniprotkb:Q7Z634|uniprotkb:Q86XH2|uniprotkb:Q96QN9|ensembl:ENSP00000355966 intact:EBI-2556811|uniprotkb:Q6ZUZ2|uniprotkb:Q86XZ0|uniprotkb:Q5T7B7|uniprotkb:Q2TB93|uniprotkb:Q5T7B5|uniprotkb:Q9NV43|uniprotkb:Q6ZU97|ensembl:ENSP00000384433 psi-mi:nek2_human(display_long)|uniprotkb:NEK2A(gene name synonym)|uniprotkb:NimA-like protein kinase 1(gene name synonym)|uniprotkb:HSPK 21(gene name synonym)|uniprotkb:NEK2(gene name)|psi-mi:NEK2(display_short)|uniprotkb:NLK1(gene name synonym)|uniprotkb:Never in mitosis A-related kinase 2(gene name synonym) psi-mi:kif24_human(display_long)|uniprotkb:C9orf48(gene name synonym)|uniprotkb:KIF24(gene name)|psi-mi:KIF24(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kim et al. (2015) pubmed:26290419|imex:IM-25477 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-11810109|imex:IM-25477-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001191111.1|refseq:NP_001191112.1|refseq:NP_002488.1|ensembl:ENSG00000117650(gene)|ensembl:ENST00000366999(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000922"(spindle pole)|go:"GO:0001824"(blastocyst development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030496"(midbody)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0046602"(regulation of mitotic centrosome separation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051299"(centrosome separation)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0051988"(regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903126"(negative regulation of centriole-centriole cohesion)|go:"GO:1904355"(positive regulation of telomere capping)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|mint:P51955|rcsb pdb:2JAV|rcsb pdb:2W5A|rcsb pdb:2W5B|rcsb pdb:2W5H|rcsb pdb:2WQO|rcsb pdb:2XK3|rcsb pdb:2XK4|rcsb pdb:2XK6|rcsb pdb:2XK7|rcsb pdb:2XK8|rcsb pdb:2XKC|rcsb pdb:2XKD|rcsb pdb:2XKE|rcsb pdb:2XKF|rcsb pdb:2XNM|rcsb pdb:2XNN|rcsb pdb:2XNO|rcsb pdb:2XNP|rcsb pdb:4A4X|rcsb pdb:4AFE|rcsb pdb:5M51|rcsb pdb:5M53|rcsb pdb:5M55|rcsb pdb:5M57|rcsb pdb:6SGD|rcsb pdb:6SGH|rcsb pdb:6SGI|rcsb pdb:6SGK|rcsb pdb:6SK9|rcsb pdb:6TM5|reactome:R-HSA-179409|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:XP_005273204.1 refseq:XP_011516165.1|ensembl:ENSG00000186638(gene)|ensembl:ENST00000402558(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007019"(microtubule depolymerization)|go:"GO:0008017"(microtubule binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0060271"(cilium assembly)|go:"GO:1990939"|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR019821|interpro:IPR027417|interpro:IPR036961|reactome:R-HSA-5620912|refseq:NP_919289.2|refseq:XP_016870186.1 - - - figure legend:1b|comment:"A slower migrating Kif24 form observed when using wildtype NEK2. This form is lost when using catalytically inactive (KD) NEK2 or phosphatase treatment."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2016/07/07 2016/07/07 rogid:7iozc82+IF+sGyerzvp571Uc1RM9606 rogid:ZaT+RA4urWXtHuUy20eBs/X6hp89606 rigid:c6zuXzeScWBYCi685KvE9fS+1cc false green fluorescent protein tag:?-? flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P51955 uniprotkb:Q5T7B8 intact:EBI-633182|uniprotkb:Q53FD6|uniprotkb:Q5VXZ1|intact:EBI-4311380|uniprotkb:Q5I1Z9|uniprotkb:Q6NZX8|uniprotkb:Q7Z634|uniprotkb:Q86XH2|uniprotkb:Q96QN9|ensembl:ENSP00000355966 intact:EBI-2556811|uniprotkb:Q6ZUZ2|uniprotkb:Q86XZ0|uniprotkb:Q5T7B7|uniprotkb:Q2TB93|uniprotkb:Q5T7B5|uniprotkb:Q9NV43|uniprotkb:Q6ZU97|ensembl:ENSP00000384433 psi-mi:nek2_human(display_long)|uniprotkb:NEK2A(gene name synonym)|uniprotkb:NimA-like protein kinase 1(gene name synonym)|uniprotkb:HSPK 21(gene name synonym)|uniprotkb:NEK2(gene name)|psi-mi:NEK2(display_short)|uniprotkb:NLK1(gene name synonym)|uniprotkb:Never in mitosis A-related kinase 2(gene name synonym) psi-mi:kif24_human(display_long)|uniprotkb:C9orf48(gene name synonym)|uniprotkb:KIF24(gene name)|psi-mi:KIF24(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kim et al. (2015) pubmed:26290419|imex:IM-25477 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-11810105|imex:IM-25477-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001191111.1|refseq:NP_001191112.1|refseq:NP_002488.1|ensembl:ENSG00000117650(gene)|ensembl:ENST00000366999(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000922"(spindle pole)|go:"GO:0001824"(blastocyst development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030496"(midbody)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0046602"(regulation of mitotic centrosome separation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051299"(centrosome separation)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0051988"(regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903126"(negative regulation of centriole-centriole cohesion)|go:"GO:1904355"(positive regulation of telomere capping)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|mint:P51955|rcsb pdb:2JAV|rcsb pdb:2W5A|rcsb pdb:2W5B|rcsb pdb:2W5H|rcsb pdb:2WQO|rcsb pdb:2XK3|rcsb pdb:2XK4|rcsb pdb:2XK6|rcsb pdb:2XK7|rcsb pdb:2XK8|rcsb pdb:2XKC|rcsb pdb:2XKD|rcsb pdb:2XKE|rcsb pdb:2XKF|rcsb pdb:2XNM|rcsb pdb:2XNN|rcsb pdb:2XNO|rcsb pdb:2XNP|rcsb pdb:4A4X|rcsb pdb:4AFE|rcsb pdb:5M51|rcsb pdb:5M53|rcsb pdb:5M55|rcsb pdb:5M57|rcsb pdb:6SGD|rcsb pdb:6SGH|rcsb pdb:6SGI|rcsb pdb:6SGK|rcsb pdb:6SK9|rcsb pdb:6TM5|reactome:R-HSA-179409|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:XP_005273204.1 refseq:XP_011516165.1|ensembl:ENSG00000186638(gene)|ensembl:ENST00000402558(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007019"(microtubule depolymerization)|go:"GO:0008017"(microtubule binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0060271"(cilium assembly)|go:"GO:1990939"|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR019821|interpro:IPR027417|interpro:IPR036961|reactome:R-HSA-5620912|refseq:NP_919289.2|refseq:XP_016870186.1 - - - figure legend:1b|comment:"A slower migrating Kif24 form observed when using wildtype NEK2. This form is lost when using catalytically inactive (KD) NEK2 or phosphatase treatment."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2016/07/07 2016/07/07 rogid:7iozc82+IF+sGyerzvp571Uc1RM9606 rogid:ZaT+RA4urWXtHuUy20eBs/X6hp89606 rigid:c6zuXzeScWBYCi685KvE9fS+1cc false green fluorescent protein tag:?-? flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q5T7B8 uniprotkb:Q5T7B8 intact:EBI-2556811|uniprotkb:Q6ZUZ2|uniprotkb:Q86XZ0|uniprotkb:Q5T7B7|uniprotkb:Q2TB93|uniprotkb:Q5T7B5|uniprotkb:Q9NV43|uniprotkb:Q6ZU97|ensembl:ENSP00000384433 intact:EBI-2556811|uniprotkb:Q6ZUZ2|uniprotkb:Q86XZ0|uniprotkb:Q5T7B7|uniprotkb:Q2TB93|uniprotkb:Q5T7B5|uniprotkb:Q9NV43|uniprotkb:Q6ZU97|ensembl:ENSP00000384433 psi-mi:kif24_human(display_long)|uniprotkb:C9orf48(gene name synonym)|uniprotkb:KIF24(gene name)|psi-mi:KIF24(display_short) psi-mi:kif24_human(display_long)|uniprotkb:C9orf48(gene name synonym)|uniprotkb:KIF24(gene name)|psi-mi:KIF24(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kim et al. (2015) pubmed:26290419|imex:IM-25477 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-11811460|imex:IM-25477-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011516165.1|ensembl:ENSG00000186638(gene)|ensembl:ENST00000402558(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007019"(microtubule depolymerization)|go:"GO:0008017"(microtubule binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0060271"(cilium assembly)|go:"GO:1990939"|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR019821|interpro:IPR027417|interpro:IPR036961|reactome:R-HSA-5620912|refseq:NP_919289.2|refseq:XP_016870186.1 refseq:XP_011516165.1|ensembl:ENSG00000186638(gene)|ensembl:ENST00000402558(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007019"(microtubule depolymerization)|go:"GO:0008017"(microtubule binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0060271"(cilium assembly)|go:"GO:1990939"|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR019821|interpro:IPR027417|interpro:IPR036961|reactome:R-HSA-5620912|refseq:NP_919289.2|refseq:XP_016870186.1 - - - figure legend:supplementary 11A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2016/07/07 2016/07/07 rogid:ZaT+RA4urWXtHuUy20eBs/X6hp89606 rogid:ZaT+RA4urWXtHuUy20eBs/X6hp89606 rigid:4AvuEzmpPNd5Kokm8hMt5KhbFIs false green fluorescent protein tag:?-?|sufficient binding region:924-1368 flag tag:?-?|sufficient binding region:1-923 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P51955 uniprotkb:Q5T7B8 intact:EBI-633182|uniprotkb:Q53FD6|uniprotkb:Q5VXZ1|intact:EBI-4311380|uniprotkb:Q5I1Z9|uniprotkb:Q6NZX8|uniprotkb:Q7Z634|uniprotkb:Q86XH2|uniprotkb:Q96QN9|ensembl:ENSP00000355966 intact:EBI-2556811|uniprotkb:Q6ZUZ2|uniprotkb:Q86XZ0|uniprotkb:Q5T7B7|uniprotkb:Q2TB93|uniprotkb:Q5T7B5|uniprotkb:Q9NV43|uniprotkb:Q6ZU97|ensembl:ENSP00000384433 psi-mi:nek2_human(display_long)|uniprotkb:NEK2A(gene name synonym)|uniprotkb:NimA-like protein kinase 1(gene name synonym)|uniprotkb:HSPK 21(gene name synonym)|uniprotkb:NEK2(gene name)|psi-mi:NEK2(display_short)|uniprotkb:NLK1(gene name synonym)|uniprotkb:Never in mitosis A-related kinase 2(gene name synonym) psi-mi:kif24_human(display_long)|uniprotkb:C9orf48(gene name synonym)|uniprotkb:KIF24(gene name)|psi-mi:KIF24(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kim et al. (2015) pubmed:26290419|imex:IM-25477 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-11811402|imex:IM-25477-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001191111.1|refseq:NP_001191112.1|refseq:NP_002488.1|ensembl:ENSG00000117650(gene)|ensembl:ENST00000366999(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000922"(spindle pole)|go:"GO:0001824"(blastocyst development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030496"(midbody)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0046602"(regulation of mitotic centrosome separation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051299"(centrosome separation)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0051988"(regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903126"(negative regulation of centriole-centriole cohesion)|go:"GO:1904355"(positive regulation of telomere capping)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|mint:P51955|rcsb pdb:2JAV|rcsb pdb:2W5A|rcsb pdb:2W5B|rcsb pdb:2W5H|rcsb pdb:2WQO|rcsb pdb:2XK3|rcsb pdb:2XK4|rcsb pdb:2XK6|rcsb pdb:2XK7|rcsb pdb:2XK8|rcsb pdb:2XKC|rcsb pdb:2XKD|rcsb pdb:2XKE|rcsb pdb:2XKF|rcsb pdb:2XNM|rcsb pdb:2XNN|rcsb pdb:2XNO|rcsb pdb:2XNP|rcsb pdb:4A4X|rcsb pdb:4AFE|rcsb pdb:5M51|rcsb pdb:5M53|rcsb pdb:5M55|rcsb pdb:5M57|rcsb pdb:6SGD|rcsb pdb:6SGH|rcsb pdb:6SGI|rcsb pdb:6SGK|rcsb pdb:6SK9|rcsb pdb:6TM5|reactome:R-HSA-179409|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:XP_005273204.1 refseq:XP_011516165.1|ensembl:ENSG00000186638(gene)|ensembl:ENST00000402558(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007019"(microtubule depolymerization)|go:"GO:0008017"(microtubule binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0060271"(cilium assembly)|go:"GO:1990939"|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR019821|interpro:IPR027417|interpro:IPR036961|reactome:R-HSA-5620912|refseq:NP_919289.2|refseq:XP_016870186.1 - - - figure legend:supplementary 1a and b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2016/07/07 2016/07/07 rogid:7iozc82+IF+sGyerzvp571Uc1RM9606 rogid:ZaT+RA4urWXtHuUy20eBs/X6hp89606 rigid:c6zuXzeScWBYCi685KvE9fS+1cc false - flag tag:?-?|necessary binding region:924-999|binding-associated region:509-547 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q5T7B8 uniprotkb:P51955 intact:EBI-2556811|uniprotkb:Q6ZUZ2|uniprotkb:Q86XZ0|uniprotkb:Q5T7B7|uniprotkb:Q2TB93|uniprotkb:Q5T7B5|uniprotkb:Q9NV43|uniprotkb:Q6ZU97|ensembl:ENSP00000384433 intact:EBI-633182|uniprotkb:Q53FD6|uniprotkb:Q5VXZ1|intact:EBI-4311380|uniprotkb:Q5I1Z9|uniprotkb:Q6NZX8|uniprotkb:Q7Z634|uniprotkb:Q86XH2|uniprotkb:Q96QN9|ensembl:ENSP00000355966 psi-mi:kif24_human(display_long)|uniprotkb:C9orf48(gene name synonym)|uniprotkb:KIF24(gene name)|psi-mi:KIF24(display_short) psi-mi:nek2_human(display_long)|uniprotkb:NEK2A(gene name synonym)|uniprotkb:NimA-like protein kinase 1(gene name synonym)|uniprotkb:HSPK 21(gene name synonym)|uniprotkb:NEK2(gene name)|psi-mi:NEK2(display_short)|uniprotkb:NLK1(gene name synonym)|uniprotkb:Never in mitosis A-related kinase 2(gene name synonym) psi-mi:"MI:0424"(protein kinase assay) Kim et al. (2015) pubmed:26290419|imex:IM-25477 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0217"(phosphorylation reaction) psi-mi:"MI:0486"(UniProt) intact:EBI-11811433|imex:IM-25477-6 - - psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011516165.1|ensembl:ENSG00000186638(gene)|ensembl:ENST00000402558(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007019"(microtubule depolymerization)|go:"GO:0008017"(microtubule binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0060271"(cilium assembly)|go:"GO:1990939"|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR019821|interpro:IPR027417|interpro:IPR036961|reactome:R-HSA-5620912|refseq:NP_919289.2|refseq:XP_016870186.1 refseq:NP_001191111.1|refseq:NP_001191112.1|refseq:NP_002488.1|ensembl:ENSG00000117650(gene)|ensembl:ENST00000366999(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000922"(spindle pole)|go:"GO:0001824"(blastocyst development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030496"(midbody)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0046602"(regulation of mitotic centrosome separation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051299"(centrosome separation)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0051988"(regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903126"(negative regulation of centriole-centriole cohesion)|go:"GO:1904355"(positive regulation of telomere capping)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|mint:P51955|rcsb pdb:2JAV|rcsb pdb:2W5A|rcsb pdb:2W5B|rcsb pdb:2W5H|rcsb pdb:2WQO|rcsb pdb:2XK3|rcsb pdb:2XK4|rcsb pdb:2XK6|rcsb pdb:2XK7|rcsb pdb:2XK8|rcsb pdb:2XKC|rcsb pdb:2XKD|rcsb pdb:2XKE|rcsb pdb:2XKF|rcsb pdb:2XNM|rcsb pdb:2XNN|rcsb pdb:2XNO|rcsb pdb:2XNP|rcsb pdb:4A4X|rcsb pdb:4AFE|rcsb pdb:5M51|rcsb pdb:5M53|rcsb pdb:5M55|rcsb pdb:5M57|rcsb pdb:6SGD|rcsb pdb:6SGH|rcsb pdb:6SGI|rcsb pdb:6SGK|rcsb pdb:6SK9|rcsb pdb:6TM5|reactome:R-HSA-179409|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:XP_005273204.1 - - - figure legend:1C and supplementary 2|causality statement:P51955 increases activity of Q5T7B8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/07/07 2016/07/07 rogid:ZaT+RA4urWXtHuUy20eBs/X6hp89606 rogid:7iozc82+IF+sGyerzvp571Uc1RM9606 rigid:c6zuXzeScWBYCi685KvE9fS+1cc false sufficient binding region:548-825|mutation decreasing interaction:621-622|glutathione s tranferase tag:?-?|O-phospho-L-serine:789-789 flag tag:?-? - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:Q5T7B8 uniprotkb:P51955 intact:EBI-2556811|uniprotkb:Q6ZUZ2|uniprotkb:Q86XZ0|uniprotkb:Q5T7B7|uniprotkb:Q2TB93|uniprotkb:Q5T7B5|uniprotkb:Q9NV43|uniprotkb:Q6ZU97|ensembl:ENSP00000384433 intact:EBI-633182|uniprotkb:Q53FD6|uniprotkb:Q5VXZ1|intact:EBI-4311380|uniprotkb:Q5I1Z9|uniprotkb:Q6NZX8|uniprotkb:Q7Z634|uniprotkb:Q86XH2|uniprotkb:Q96QN9|ensembl:ENSP00000355966 psi-mi:kif24_human(display_long)|uniprotkb:C9orf48(gene name synonym)|uniprotkb:KIF24(gene name)|psi-mi:KIF24(display_short) psi-mi:nek2_human(display_long)|uniprotkb:NEK2A(gene name synonym)|uniprotkb:NimA-like protein kinase 1(gene name synonym)|uniprotkb:HSPK 21(gene name synonym)|uniprotkb:NEK2(gene name)|psi-mi:NEK2(display_short)|uniprotkb:NLK1(gene name synonym)|uniprotkb:Never in mitosis A-related kinase 2(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Kim et al. (2015) pubmed:26290419|imex:IM-25477 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-11811449|imex:IM-25477-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011516165.1|ensembl:ENSG00000186638(gene)|ensembl:ENST00000402558(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007019"(microtubule depolymerization)|go:"GO:0008017"(microtubule binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0060271"(cilium assembly)|go:"GO:1990939"|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR019821|interpro:IPR027417|interpro:IPR036961|reactome:R-HSA-5620912|refseq:NP_919289.2|refseq:XP_016870186.1 refseq:NP_001191111.1|refseq:NP_001191112.1|refseq:NP_002488.1|ensembl:ENSG00000117650(gene)|ensembl:ENST00000366999(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000922"(spindle pole)|go:"GO:0001824"(blastocyst development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030496"(midbody)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0046602"(regulation of mitotic centrosome separation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051299"(centrosome separation)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0051988"(regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903126"(negative regulation of centriole-centriole cohesion)|go:"GO:1904355"(positive regulation of telomere capping)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|mint:P51955|rcsb pdb:2JAV|rcsb pdb:2W5A|rcsb pdb:2W5B|rcsb pdb:2W5H|rcsb pdb:2WQO|rcsb pdb:2XK3|rcsb pdb:2XK4|rcsb pdb:2XK6|rcsb pdb:2XK7|rcsb pdb:2XK8|rcsb pdb:2XKC|rcsb pdb:2XKD|rcsb pdb:2XKE|rcsb pdb:2XKF|rcsb pdb:2XNM|rcsb pdb:2XNN|rcsb pdb:2XNO|rcsb pdb:2XNP|rcsb pdb:4A4X|rcsb pdb:4AFE|rcsb pdb:5M51|rcsb pdb:5M53|rcsb pdb:5M55|rcsb pdb:5M57|rcsb pdb:6SGD|rcsb pdb:6SGH|rcsb pdb:6SGI|rcsb pdb:6SGK|rcsb pdb:6SK9|rcsb pdb:6TM5|reactome:R-HSA-179409|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:XP_005273204.1 - - - figure legend:2b|comment:Observed during s/G2 phase|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2016/07/07 2016/07/07 rogid:ZaT+RA4urWXtHuUy20eBs/X6hp89606 rogid:7iozc82+IF+sGyerzvp571Uc1RM9606 rigid:c6zuXzeScWBYCi685KvE9fS+1cc false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q5T7B8 uniprotkb:Q5T7B8 intact:EBI-2556811|uniprotkb:Q6ZUZ2|uniprotkb:Q86XZ0|uniprotkb:Q5T7B7|uniprotkb:Q2TB93|uniprotkb:Q5T7B5|uniprotkb:Q9NV43|uniprotkb:Q6ZU97|ensembl:ENSP00000384433 intact:EBI-2556811|uniprotkb:Q6ZUZ2|uniprotkb:Q86XZ0|uniprotkb:Q5T7B7|uniprotkb:Q2TB93|uniprotkb:Q5T7B5|uniprotkb:Q9NV43|uniprotkb:Q6ZU97|ensembl:ENSP00000384433 psi-mi:kif24_human(display_long)|uniprotkb:C9orf48(gene name synonym)|uniprotkb:KIF24(gene name)|psi-mi:KIF24(display_short) psi-mi:kif24_human(display_long)|uniprotkb:C9orf48(gene name synonym)|uniprotkb:KIF24(gene name)|psi-mi:KIF24(display_short) psi-mi:"MI:0055"(fluorescent resonance energy transfer) Kim et al. (2015) pubmed:26290419|imex:IM-25477 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:1126"(self interaction) psi-mi:"MI:0486"(UniProt) intact:EBI-11811475|imex:IM-25477-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0865"(fluorescence acceptor donor pair) psi-mi:"MI:0865"(fluorescence acceptor donor pair) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011516165.1|ensembl:ENSG00000186638(gene)|ensembl:ENST00000402558(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007019"(microtubule depolymerization)|go:"GO:0008017"(microtubule binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0060271"(cilium assembly)|go:"GO:1990939"|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR019821|interpro:IPR027417|interpro:IPR036961|reactome:R-HSA-5620912|refseq:NP_919289.2|refseq:XP_016870186.1 refseq:XP_011516165.1|ensembl:ENSG00000186638(gene)|ensembl:ENST00000402558(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007019"(microtubule depolymerization)|go:"GO:0008017"(microtubule binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0060271"(cilium assembly)|go:"GO:1990939"|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR019821|interpro:IPR027417|interpro:IPR036961|reactome:R-HSA-5620912|refseq:NP_919289.2|refseq:XP_016870186.1 - - - figure legend:5c and supplemtary 11b|antagonist:"NEK2 (catalytic active form)"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2016/07/07 2016/07/07 rogid:ZaT+RA4urWXtHuUy20eBs/X6hp89606 rogid:ZaT+RA4urWXtHuUy20eBs/X6hp89606 rigid:a1PRH0R0BBuA1Lpf7MFmRiUcnlM false fluorophore:n-n|fluorophore:c-c fluorophore:n-n|fluorophore:c-c - 0 psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence)