#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
intact:EBI-15013415	intact:EBI-13919755	rnacentral:URS000035C796_9606	rnacentral:URS00003F07BD_9606	psi-mi:u6-1_human_snrna(display_short)|psi-mi:EBI-15013415(display_long)	psi-mi:snrna u4-1(display_short)|psi-mi:EBI-13919755(display_long)	psi-mi:"MI:0413"(electrophoretic mobility shift assay)	Liu et al. (2014)	pubmed:26161500|imex:IM-25735	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13918705|imex:IM-25735-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0607"(small nuclear rna)	psi-mi:"MI:0607"(small nuclear rna)	hgnc:"HGNC:10227"(see-also)	-	-	-	-	figure legend:Fig1B|comment:the U4/U6 construct only contains stem II plus 13 nucleotides of U6 and the two RNAs are linked by GAAA loop|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:92.0x10^-8(molar)	2016/10/14	2017/08/09	-	-	-	false	binding-associated region:?-?	binding-associated region:?-?	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
intact:EBI-15013415	uniprotkb:O43395	rnacentral:URS000035C796_9606	intact:EBI-744322|uniprotkb:O43446|uniprotkb:Q5VT54|uniprotkb:B4DSY9|intact:EBI-28983618|ensembl:ENSP00000315379	psi-mi:u6-1_human_snrna(display_short)|psi-mi:EBI-15013415(display_long)	psi-mi:prpf3_human(display_long)|uniprotkb:Pre-mRNA-splicing factor 3(gene name synonym)|uniprotkb:U4/U6 snRNP 90 kDa protein(gene name synonym)|uniprotkb:PRPF3(gene name)|psi-mi:PRPF3(display_short)|uniprotkb:HPRP3(gene name synonym)|uniprotkb:PRP3(gene name synonym)	psi-mi:"MI:0413"(electrophoretic mobility shift assay)	Liu et al. (2014)	pubmed:26161500|imex:IM-25735	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13918705|imex:IM-25735-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0607"(small nuclear rna)	psi-mi:"MI:0326"(protein)	hgnc:"HGNC:10227"(see-also)	refseq:NP_004689.1|ensembl:ENSP00000315379|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0015030"(Cajal body)|go:"GO:0016607"(nuclear speck)|go:"GO:0042802"(identical protein binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|interpro:IPR002483(Splicing factor PWI)|interpro:IPR010541(Protein of unknown function DUF1115)|interpro:IPR013881(Pre-mRNA-splicing factor 3)|interpro:IPR027104|interpro:IPR036483|mint:O43395|rcsb pdb:1X4Q|rcsb pdb:3JCR|rcsb pdb:5O9Z|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6QW6|rcsb pdb:6QX9|reactome:R-HSA-72163|ensembl:ENSG00000117360(gene)|ensembl:ENST00000324862(transcript)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|dip:DIP-34508N	-	-	-	figure legend:Fig1B|comment:the U4/U6 construct only contains stem II plus 13 nucleotides of U6 and the two RNAs are linked by GAAA loop|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:92.0x10^-8(molar)	2016/10/14	2017/08/09	-	rogid:Y2aO1gQjTU8JERVtrLpgbXq7nLU9606	-	false	binding-associated region:?-?	maltose binding protein tag:n-n|his tag:c-c|sufficient binding region:195-683	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
intact:EBI-13919755	uniprotkb:O43395	rnacentral:URS00003F07BD_9606	intact:EBI-744322|uniprotkb:O43446|uniprotkb:Q5VT54|uniprotkb:B4DSY9|intact:EBI-28983618|ensembl:ENSP00000315379	psi-mi:snrna u4-1(display_short)|psi-mi:EBI-13919755(display_long)	psi-mi:prpf3_human(display_long)|uniprotkb:Pre-mRNA-splicing factor 3(gene name synonym)|uniprotkb:U4/U6 snRNP 90 kDa protein(gene name synonym)|uniprotkb:PRPF3(gene name)|psi-mi:PRPF3(display_short)|uniprotkb:HPRP3(gene name synonym)|uniprotkb:PRP3(gene name synonym)	psi-mi:"MI:0413"(electrophoretic mobility shift assay)	Liu et al. (2014)	pubmed:26161500|imex:IM-25735	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13949452|imex:IM-25735-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0607"(small nuclear rna)	psi-mi:"MI:0326"(protein)	-	refseq:NP_004689.1|ensembl:ENSP00000315379|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0015030"(Cajal body)|go:"GO:0016607"(nuclear speck)|go:"GO:0042802"(identical protein binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|interpro:IPR002483(Splicing factor PWI)|interpro:IPR010541(Protein of unknown function DUF1115)|interpro:IPR013881(Pre-mRNA-splicing factor 3)|interpro:IPR027104|interpro:IPR036483|mint:O43395|rcsb pdb:1X4Q|rcsb pdb:3JCR|rcsb pdb:5O9Z|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6QW6|rcsb pdb:6QX9|reactome:R-HSA-72163|ensembl:ENSG00000117360(gene)|ensembl:ENST00000324862(transcript)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|dip:DIP-34508N	-	-	-	figure legend:Fig1B|comment:the U4/U6 construct only contains stem II plus 13 nucleotides of U6 and the two RNAs are linked by GAAA loop|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/10/14	2017/08/09	-	rogid:Y2aO1gQjTU8JERVtrLpgbXq7nLU9606	-	false	binding-associated region:?-?	glutathione s tranferase tag:n-n|sufficient binding region:484-683	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
intact:EBI-13919755	intact:EBI-15013415	rnacentral:URS00003F07BD_9606	rnacentral:URS000035C796_9606	psi-mi:snrna u4-1(display_short)|psi-mi:EBI-13919755(display_long)	psi-mi:u6-1_human_snrna(display_short)|psi-mi:EBI-15013415(display_long)	psi-mi:"MI:0413"(electrophoretic mobility shift assay)	Liu et al. (2014)	pubmed:26161500|imex:IM-25735	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13949452|imex:IM-25735-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0607"(small nuclear rna)	psi-mi:"MI:0607"(small nuclear rna)	-	hgnc:"HGNC:10227"(see-also)	-	-	-	figure legend:Fig1B|comment:the U4/U6 construct only contains stem II plus 13 nucleotides of U6 and the two RNAs are linked by GAAA loop|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/10/14	2017/08/09	-	-	-	false	binding-associated region:?-?	binding-associated region:?-?	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
intact:EBI-10824938	uniprotkb:Q03338	rnacentral:URS00006184A9_559292	intact:EBI-421|uniprotkb:D6VT97|ensemblfungi:YDR473C	psi-mi:snru6_yeast(display_short)|psi-mi:EBI-10824938(display_long)	psi-mi:prp3_yeast(display_long)|uniprotkb:PRP3(gene name)|psi-mi:PRP3(display_short)|uniprotkb:RNA3(gene name synonym)|uniprotkb:YDR473C(locus name)|uniprotkb:D8035.16(orf name)|uniprotkb:Pre-mRNA-splicing factor 3(gene name synonym)	psi-mi:"MI:0413"(electrophoretic mobility shift assay)	Liu et al. (2014)	pubmed:26161500|imex:IM-25735	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13949516|imex:IM-25735-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0607"(small nuclear rna)	psi-mi:"MI:0326"(protein)	-	sgd:S000002881|refseq:NP_010761.3|ensemblfungi:YDR473C(gene)|ensemblfungi:YDR473C_mRNA(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|interpro:IPR010541(Protein of unknown function DUF1115)|interpro:IPR013881(Pre-mRNA-splicing factor 3)|interpro:IPR027104|rcsb pdb:3JCM|rcsb pdb:4YHU|rcsb pdb:4YHV|rcsb pdb:4YHW|rcsb pdb:5GAN|rcsb pdb:5GAP|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|dip:DIP-5266N|mint:Q03338	-	-	crc64:E977FD9F708BDD91	figure legend:Fig1C, 1E, 1F; Fig4 I, J|comment:the U4/U6 construct only contains stem II plus 13 nucleotides of U6|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:92.0x10^-8 ~0.04(molar)	2016/10/14	2017/05/09	-	rogid:KE0Y/kRXTq9LXt4PGsKnRcY7Sqg559292	-	false	mutation with no effect:81-81|mutation decreasing interaction:82-82|mutation decreasing interaction:85-85|mutation decreasing interaction:86-86|mutation decreasing interaction:69-69|binding-associated region:64-88	mutation decreasing interaction:355-355|mutation decreasing interaction strength:304-304|mutation disrupting interaction:353-353|mutation with no effect:354-354|mutation with no effect:355-355|sufficient binding region:325-469(IPR010541)|mutation decreasing interaction strength:322-322|mutation with no effect:358-358|mutation with no effect:361-361|mutation with no effect:362-362|mutation with no effect:364-364|mutation disrupting interaction:399-399|mutation with no effect:409-409|mutation decreasing interaction:441-441	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
intact:EBI-10824938	intact:EBI-10054797	rnacentral:URS00006184A9_559292	rnacentral:URS00001143F5_559292	psi-mi:snru6_yeast(display_short)|psi-mi:EBI-10824938(display_long)	psi-mi:snr14_u4_yeast(display_short)|psi-mi:EBI-10054797(display_long)	psi-mi:"MI:0413"(electrophoretic mobility shift assay)	Liu et al. (2014)	pubmed:26161500|imex:IM-25735	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13949516|imex:IM-25735-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0607"(small nuclear rna)	psi-mi:"MI:0607"(small nuclear rna)	-	-	-	-	-	figure legend:Fig1C, 1E, 1F; Fig4 I, J|comment:the U4/U6 construct only contains stem II plus 13 nucleotides of U6|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:92.0x10^-8 ~0.04(molar)	2016/10/14	2017/05/09	-	-	-	false	mutation with no effect:81-81|mutation decreasing interaction:82-82|mutation decreasing interaction:85-85|mutation decreasing interaction:86-86|mutation decreasing interaction:69-69|binding-associated region:64-88	mutation decreasing interaction:12-12|binding-associated region:1-17	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
intact:EBI-10824938	uniprotkb:Q03338	rnacentral:URS00006184A9_559292	intact:EBI-421|uniprotkb:D6VT97|ensemblfungi:YDR473C	psi-mi:snru6_yeast(display_short)|psi-mi:EBI-10824938(display_long)	psi-mi:prp3_yeast(display_long)|uniprotkb:PRP3(gene name)|psi-mi:PRP3(display_short)|uniprotkb:RNA3(gene name synonym)|uniprotkb:YDR473C(locus name)|uniprotkb:D8035.16(orf name)|uniprotkb:Pre-mRNA-splicing factor 3(gene name synonym)	psi-mi:"MI:0413"(electrophoretic mobility shift assay)	Liu et al. (2014)	pubmed:26161500|imex:IM-25735	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-14060289|imex:IM-25735-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0607"(small nuclear rna)	psi-mi:"MI:0326"(protein)	-	sgd:S000002881|refseq:NP_010761.3|ensemblfungi:YDR473C(gene)|ensemblfungi:YDR473C_mRNA(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|interpro:IPR010541(Protein of unknown function DUF1115)|interpro:IPR013881(Pre-mRNA-splicing factor 3)|interpro:IPR027104|rcsb pdb:3JCM|rcsb pdb:4YHU|rcsb pdb:4YHV|rcsb pdb:4YHW|rcsb pdb:5GAN|rcsb pdb:5GAP|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|dip:DIP-5266N|mint:Q03338	-	-	crc64:E977FD9F708BDD91	figure legend:Fig2C|comment:The U4/U6 construct is different from the one used in  EBI-13949516 and the two full lenght RNAs are fused|comment:The co-presence of Snu13 and Prp31 increase the binding|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/10/14	2017/05/09	-	rogid:KE0Y/kRXTq9LXt4PGsKnRcY7Sqg559292	-	false	binding-associated region:?-?	sufficient binding region:325-469	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
intact:EBI-10824938	intact:EBI-10054797	rnacentral:URS00006184A9_559292	rnacentral:URS00001143F5_559292	psi-mi:snru6_yeast(display_short)|psi-mi:EBI-10824938(display_long)	psi-mi:snr14_u4_yeast(display_short)|psi-mi:EBI-10054797(display_long)	psi-mi:"MI:0413"(electrophoretic mobility shift assay)	Liu et al. (2014)	pubmed:26161500|imex:IM-25735	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-14060289|imex:IM-25735-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0607"(small nuclear rna)	psi-mi:"MI:0607"(small nuclear rna)	-	-	-	-	-	figure legend:Fig2C|comment:The U4/U6 construct is different from the one used in  EBI-13949516 and the two full lenght RNAs are fused|comment:The co-presence of Snu13 and Prp31 increase the binding|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/10/14	2017/05/09	-	-	-	false	binding-associated region:?-?	binding-associated region:?-?	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
intact:EBI-10824938	uniprotkb:P39990	rnacentral:URS00006184A9_559292	intact:EBI-12032|ensemblfungi:YEL026W|uniprotkb:D3DLM2	psi-mi:snru6_yeast(display_short)|psi-mi:EBI-10824938(display_long)	psi-mi:snu13_yeast(display_long)|uniprotkb:YEL026W(locus name)|uniprotkb:SNU13(gene name)|psi-mi:SNU13(display_short)|uniprotkb:Small nuclear ribonucleoprotein-associated protein 1(gene name synonym)	psi-mi:"MI:0413"(electrophoretic mobility shift assay)	Liu et al. (2014)	pubmed:26161500|imex:IM-25735	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-14060329|imex:IM-25735-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0607"(small nuclear rna)	psi-mi:"MI:0326"(protein)	-	ensemblfungi:YEL026W(gene)|ensemblfungi:YEL026W_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0031428"(box C/D RNP complex)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:1905216"(positive regulation of RNA binding)|interpro:IPR002415(High mobility group-like nuclear protein)|interpro:IPR004037(Ribosomal protein L7Ae)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR018492|interpro:IPR029064|rcsb pdb:1ZWZ|rcsb pdb:2ALE|rcsb pdb:3JCM|go:"GO:0005654"(nucleoplasm)|rcsb pdb:5GAN|rcsb pdb:5GAP|rcsb pdb:5NRL|rcsb pdb:5TZS|rcsb pdb:5WLC|rcsb pdb:5WYJ|rcsb pdb:5WYK|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6ND4|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:7AJT|rcsb pdb:7AJU|rcsb pdb:4NUT|reactome:R-SCE-6791226|refseq:NP_010888.1|sgd:S000000752|mint:P39990|dip:DIP-2870N	-	-	crc64:4489780153E8F182	figure legend:Fig2C|comment:The U4/U6 construct is different from the one used in  EBI-13949516 and the two full lenght RNAs are fused|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/10/14	2017/05/09	-	rogid:4C07wkvZ4Nts4Oxw4/L7QMkwcmE559292	-	false	binding-associated region:?-?	-	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
intact:EBI-10824938	intact:EBI-10054797	rnacentral:URS00006184A9_559292	rnacentral:URS00001143F5_559292	psi-mi:snru6_yeast(display_short)|psi-mi:EBI-10824938(display_long)	psi-mi:snr14_u4_yeast(display_short)|psi-mi:EBI-10054797(display_long)	psi-mi:"MI:0413"(electrophoretic mobility shift assay)	Liu et al. (2014)	pubmed:26161500|imex:IM-25735	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-14060329|imex:IM-25735-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0607"(small nuclear rna)	psi-mi:"MI:0607"(small nuclear rna)	-	-	-	-	-	figure legend:Fig2C|comment:The U4/U6 construct is different from the one used in  EBI-13949516 and the two full lenght RNAs are fused|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/10/14	2017/05/09	-	-	-	false	binding-associated region:?-?	binding-associated region:?-?	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
intact:EBI-10824938	uniprotkb:P49704	rnacentral:URS00006184A9_559292	intact:EBI-347|uniprotkb:Q66R99|uniprotkb:D6VUM3|ensemblfungi:YGR091W	psi-mi:snru6_yeast(display_short)|psi-mi:EBI-10824938(display_long)	psi-mi:prp31_yeast(display_long)|uniprotkb:PRP31(gene name)|psi-mi:PRP31(display_short)|uniprotkb:YGR091W(locus name)	psi-mi:"MI:0413"(electrophoretic mobility shift assay)	Liu et al. (2014)	pubmed:26161500|imex:IM-25735	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-14060343|imex:IM-25735-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0607"(small nuclear rna)	psi-mi:"MI:0326"(protein)	-	refseq:NP_011605.1|sgd:S000003323|dip:DIP-5355N|mint:P49704|ensemblfungi:YGR091W(gene)|ensemblfungi:YGR091W_mRNA(transcript)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005739"(mitochondrion)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0097526"(spliceosomal tri-snRNP complex)|interpro:IPR002687(Pre-mRNA processing ribonucleoprotein, binding region)|interpro:IPR012976(NOSIC)|interpro:IPR019175|interpro:IPR027105|interpro:IPR036070|interpro:IPR042239|rcsb pdb:3JCM|rcsb pdb:5GAN|rcsb pdb:5GAP|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO	-	-	crc64:E39AC6247859FB3B	figure legend:Fig2C|comment:The U4/U6 construct is different from the one used in  EBI-13949516 and the two full lenght RNAs are fused|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/10/14	2017/05/10	-	rogid:H41JrfockxRzf+U5GKVgGxBTrW0559292	-	false	binding-associated region:?-?	sufficient binding region:1-462	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
intact:EBI-10824938	uniprotkb:P39990	rnacentral:URS00006184A9_559292	intact:EBI-12032|ensemblfungi:YEL026W|uniprotkb:D3DLM2	psi-mi:snru6_yeast(display_short)|psi-mi:EBI-10824938(display_long)	psi-mi:snu13_yeast(display_long)|uniprotkb:YEL026W(locus name)|uniprotkb:SNU13(gene name)|psi-mi:SNU13(display_short)|uniprotkb:Small nuclear ribonucleoprotein-associated protein 1(gene name synonym)	psi-mi:"MI:0413"(electrophoretic mobility shift assay)	Liu et al. (2014)	pubmed:26161500|imex:IM-25735	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-14060343|imex:IM-25735-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0607"(small nuclear rna)	psi-mi:"MI:0326"(protein)	-	ensemblfungi:YEL026W(gene)|ensemblfungi:YEL026W_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0031428"(box C/D RNP complex)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:1905216"(positive regulation of RNA binding)|interpro:IPR002415(High mobility group-like nuclear protein)|interpro:IPR004037(Ribosomal protein L7Ae)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR018492|interpro:IPR029064|rcsb pdb:1ZWZ|rcsb pdb:2ALE|rcsb pdb:3JCM|go:"GO:0005654"(nucleoplasm)|rcsb pdb:5GAN|rcsb pdb:5GAP|rcsb pdb:5NRL|rcsb pdb:5TZS|rcsb pdb:5WLC|rcsb pdb:5WYJ|rcsb pdb:5WYK|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6ND4|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:7AJT|rcsb pdb:7AJU|rcsb pdb:4NUT|reactome:R-SCE-6791226|refseq:NP_010888.1|sgd:S000000752|mint:P39990|dip:DIP-2870N	-	-	crc64:4489780153E8F182	figure legend:Fig2C|comment:The U4/U6 construct is different from the one used in  EBI-13949516 and the two full lenght RNAs are fused|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/10/14	2017/05/10	-	rogid:4C07wkvZ4Nts4Oxw4/L7QMkwcmE559292	-	false	binding-associated region:?-?	-	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
intact:EBI-10824938	intact:EBI-10054797	rnacentral:URS00006184A9_559292	rnacentral:URS00001143F5_559292	psi-mi:snru6_yeast(display_short)|psi-mi:EBI-10824938(display_long)	psi-mi:snr14_u4_yeast(display_short)|psi-mi:EBI-10054797(display_long)	psi-mi:"MI:0413"(electrophoretic mobility shift assay)	Liu et al. (2014)	pubmed:26161500|imex:IM-25735	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-14060343|imex:IM-25735-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0607"(small nuclear rna)	psi-mi:"MI:0607"(small nuclear rna)	-	-	-	-	-	figure legend:Fig2C|comment:The U4/U6 construct is different from the one used in  EBI-13949516 and the two full lenght RNAs are fused|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/10/14	2017/05/10	-	-	-	false	binding-associated region:?-?	binding-associated region:?-?	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:Q03338	intact:EBI-10054797	intact:EBI-421|uniprotkb:D6VT97|ensemblfungi:YDR473C	rnacentral:URS00001143F5_559292	psi-mi:prp3_yeast(display_long)|uniprotkb:PRP3(gene name)|psi-mi:PRP3(display_short)|uniprotkb:RNA3(gene name synonym)|uniprotkb:YDR473C(locus name)|uniprotkb:D8035.16(orf name)|uniprotkb:Pre-mRNA-splicing factor 3(gene name synonym)	psi-mi:snr14_u4_yeast(display_short)|psi-mi:EBI-10054797(display_long)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Liu et al. (2014)	pubmed:26161500|imex:IM-25735	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-14059961|imex:IM-25735-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0607"(small nuclear rna)	sgd:S000002881|refseq:NP_010761.3|ensemblfungi:YDR473C(gene)|ensemblfungi:YDR473C_mRNA(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|interpro:IPR010541(Protein of unknown function DUF1115)|interpro:IPR013881(Pre-mRNA-splicing factor 3)|interpro:IPR027104|rcsb pdb:3JCM|rcsb pdb:4YHU|rcsb pdb:4YHV|rcsb pdb:4YHW|rcsb pdb:5GAN|rcsb pdb:5GAP|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|dip:DIP-5266N|mint:Q03338	-	-	crc64:E977FD9F708BDD91	-	figure legend:Fig1D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/10/14	2017/05/09	rogid:KE0Y/kRXTq9LXt4PGsKnRcY7Sqg559292	-	-	false	sufficient binding region:296-469|sufficient binding region:325-469(IPR010541)|mutation decreasing interaction:304-304|mutation decreasing interaction:322-322	binding-associated region:1-17	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q03338	intact:EBI-10824938	intact:EBI-421|uniprotkb:D6VT97|ensemblfungi:YDR473C	rnacentral:URS00006184A9_559292	psi-mi:prp3_yeast(display_long)|uniprotkb:PRP3(gene name)|psi-mi:PRP3(display_short)|uniprotkb:RNA3(gene name synonym)|uniprotkb:YDR473C(locus name)|uniprotkb:D8035.16(orf name)|uniprotkb:Pre-mRNA-splicing factor 3(gene name synonym)	psi-mi:snru6_yeast(display_short)|psi-mi:EBI-10824938(display_long)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Liu et al. (2014)	pubmed:26161500|imex:IM-25735	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-14059961|imex:IM-25735-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0607"(small nuclear rna)	sgd:S000002881|refseq:NP_010761.3|ensemblfungi:YDR473C(gene)|ensemblfungi:YDR473C_mRNA(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|interpro:IPR010541(Protein of unknown function DUF1115)|interpro:IPR013881(Pre-mRNA-splicing factor 3)|interpro:IPR027104|rcsb pdb:3JCM|rcsb pdb:4YHU|rcsb pdb:4YHV|rcsb pdb:4YHW|rcsb pdb:5GAN|rcsb pdb:5GAP|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|dip:DIP-5266N|mint:Q03338	-	-	crc64:E977FD9F708BDD91	-	figure legend:Fig1D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/10/14	2017/05/09	rogid:KE0Y/kRXTq9LXt4PGsKnRcY7Sqg559292	-	-	false	sufficient binding region:296-469|sufficient binding region:325-469(IPR010541)|mutation decreasing interaction:304-304|mutation decreasing interaction:322-322	binding-associated region:64-93	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32639	intact:EBI-10054797	intact:EBI-861|uniprotkb:D3DM80|ensemblfungi:YER172C	rnacentral:URS00001143F5_559292	psi-mi:brr2_yeast(display_long)|uniprotkb:BRR2(gene name)|psi-mi:BRR2(display_short)|uniprotkb:RSS1(gene name synonym)|uniprotkb:SNU246(gene name synonym)|uniprotkb:YER172C(locus name)|uniprotkb:SYGP-ORF66(orf name)|uniprotkb:Protein Snu246(gene name synonym)	psi-mi:snr14_u4_yeast(display_short)|psi-mi:EBI-10054797(display_long)	psi-mi:"MI:0415"(enzymatic study)	Liu et al. (2014)	pubmed:26161500|imex:IM-25735	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0414"(enzymatic reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-14060280|imex:IM-25735-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0607"(small nuclear rna)	refseq:NP_011099.1|sgd:S000000974|dip:DIP-850N|mint:P32639|ensemblfungi:YER172C(gene)|ensemblfungi:YER172C_mRNA(transcript)|go:"GO:0000388"("spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)")|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0042802"(identical protein binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR004179(Sec63)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR027417|interpro:IPR035892|interpro:IPR036388|interpro:IPR036390|interpro:IPR041094|rcsb pdb:3HIB|rcsb pdb:3IM1|rcsb pdb:3IM2|rcsb pdb:3JCM|rcsb pdb:4BGD|rcsb pdb:5DCA|rcsb pdb:5GAN|rcsb pdb:5GAO|rcsb pdb:5GAP|rcsb pdb:5GM6|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5M52|rcsb pdb:5M5P|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:7B9V	-	-	crc64:DFAF7E3B7168D944	-	figure legend:Fig2A,B|comment:"The presence of Prp3 (296-469) inhibits the reaction"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/10/14	2017/05/28	rogid:2bNoVkou3QatkNCtPIiSdvPdgEo559292	-	-	false	-	-	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:P32639	intact:EBI-10824938	intact:EBI-861|uniprotkb:D3DM80|ensemblfungi:YER172C	rnacentral:URS00006184A9_559292	psi-mi:brr2_yeast(display_long)|uniprotkb:BRR2(gene name)|psi-mi:BRR2(display_short)|uniprotkb:RSS1(gene name synonym)|uniprotkb:SNU246(gene name synonym)|uniprotkb:YER172C(locus name)|uniprotkb:SYGP-ORF66(orf name)|uniprotkb:Protein Snu246(gene name synonym)	psi-mi:snru6_yeast(display_short)|psi-mi:EBI-10824938(display_long)	psi-mi:"MI:0415"(enzymatic study)	Liu et al. (2014)	pubmed:26161500|imex:IM-25735	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0414"(enzymatic reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-14060280|imex:IM-25735-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0607"(small nuclear rna)	refseq:NP_011099.1|sgd:S000000974|dip:DIP-850N|mint:P32639|ensemblfungi:YER172C(gene)|ensemblfungi:YER172C_mRNA(transcript)|go:"GO:0000388"("spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)")|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0042802"(identical protein binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR004179(Sec63)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR027417|interpro:IPR035892|interpro:IPR036388|interpro:IPR036390|interpro:IPR041094|rcsb pdb:3HIB|rcsb pdb:3IM1|rcsb pdb:3IM2|rcsb pdb:3JCM|rcsb pdb:4BGD|rcsb pdb:5DCA|rcsb pdb:5GAN|rcsb pdb:5GAO|rcsb pdb:5GAP|rcsb pdb:5GM6|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5M52|rcsb pdb:5M5P|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:7B9V	-	-	crc64:DFAF7E3B7168D944	-	figure legend:Fig2A,B|comment:"The presence of Prp3 (296-469) inhibits the reaction"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/10/14	2017/05/28	rogid:2bNoVkou3QatkNCtPIiSdvPdgEo559292	-	-	false	-	-	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:P32639	uniprotkb:Q03338	intact:EBI-861|uniprotkb:D3DM80|ensemblfungi:YER172C	intact:EBI-421|uniprotkb:D6VT97|ensemblfungi:YDR473C	psi-mi:brr2_yeast(display_long)|uniprotkb:BRR2(gene name)|psi-mi:BRR2(display_short)|uniprotkb:RSS1(gene name synonym)|uniprotkb:SNU246(gene name synonym)|uniprotkb:YER172C(locus name)|uniprotkb:SYGP-ORF66(orf name)|uniprotkb:Protein Snu246(gene name synonym)	psi-mi:prp3_yeast(display_long)|uniprotkb:PRP3(gene name)|psi-mi:PRP3(display_short)|uniprotkb:RNA3(gene name synonym)|uniprotkb:YDR473C(locus name)|uniprotkb:D8035.16(orf name)|uniprotkb:Pre-mRNA-splicing factor 3(gene name synonym)	psi-mi:"MI:0415"(enzymatic study)	Liu et al. (2014)	pubmed:26161500|imex:IM-25735	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0414"(enzymatic reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-15013424|imex:IM-25735-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0586"(inhibitor)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011099.1|sgd:S000000974|dip:DIP-850N|mint:P32639|ensemblfungi:YER172C(gene)|ensemblfungi:YER172C_mRNA(transcript)|go:"GO:0000388"("spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)")|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0042802"(identical protein binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR004179(Sec63)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR027417|interpro:IPR035892|interpro:IPR036388|interpro:IPR036390|interpro:IPR041094|rcsb pdb:3HIB|rcsb pdb:3IM1|rcsb pdb:3IM2|rcsb pdb:3JCM|rcsb pdb:4BGD|rcsb pdb:5DCA|rcsb pdb:5GAN|rcsb pdb:5GAO|rcsb pdb:5GAP|rcsb pdb:5GM6|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5M52|rcsb pdb:5M5P|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:7B9V	sgd:S000002881|refseq:NP_010761.3|ensemblfungi:YDR473C(gene)|ensemblfungi:YDR473C_mRNA(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|interpro:IPR010541(Protein of unknown function DUF1115)|interpro:IPR013881(Pre-mRNA-splicing factor 3)|interpro:IPR027104|rcsb pdb:3JCM|rcsb pdb:4YHU|rcsb pdb:4YHV|rcsb pdb:4YHW|rcsb pdb:5GAN|rcsb pdb:5GAP|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|dip:DIP-5266N|mint:Q03338	-	crc64:DFAF7E3B7168D944	crc64:E977FD9F708BDD91	figure legend:Fig2A,B|comment:"The presence of Prp3 (296-469) inhibits the reaction"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/10/14	2017/05/28	rogid:2bNoVkou3QatkNCtPIiSdvPdgEo559292	rogid:KE0Y/kRXTq9LXt4PGsKnRcY7Sqg559292	-	false	-	binding-associated region:296-469	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:P32639	intact:EBI-10054797	intact:EBI-861|uniprotkb:D3DM80|ensemblfungi:YER172C	rnacentral:URS00001143F5_559292	psi-mi:brr2_yeast(display_long)|uniprotkb:BRR2(gene name)|psi-mi:BRR2(display_short)|uniprotkb:RSS1(gene name synonym)|uniprotkb:SNU246(gene name synonym)|uniprotkb:YER172C(locus name)|uniprotkb:SYGP-ORF66(orf name)|uniprotkb:Protein Snu246(gene name synonym)	psi-mi:snr14_u4_yeast(display_short)|psi-mi:EBI-10054797(display_long)	psi-mi:"MI:0415"(enzymatic study)	Liu et al. (2014)	pubmed:26161500|imex:IM-25735	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0414"(enzymatic reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-15013424|imex:IM-25735-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0607"(small nuclear rna)	refseq:NP_011099.1|sgd:S000000974|dip:DIP-850N|mint:P32639|ensemblfungi:YER172C(gene)|ensemblfungi:YER172C_mRNA(transcript)|go:"GO:0000388"("spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)")|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0042802"(identical protein binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR004179(Sec63)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR027417|interpro:IPR035892|interpro:IPR036388|interpro:IPR036390|interpro:IPR041094|rcsb pdb:3HIB|rcsb pdb:3IM1|rcsb pdb:3IM2|rcsb pdb:3JCM|rcsb pdb:4BGD|rcsb pdb:5DCA|rcsb pdb:5GAN|rcsb pdb:5GAO|rcsb pdb:5GAP|rcsb pdb:5GM6|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5M52|rcsb pdb:5M5P|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:7B9V	-	-	crc64:DFAF7E3B7168D944	-	figure legend:Fig2A,B|comment:"The presence of Prp3 (296-469) inhibits the reaction"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/10/14	2017/05/28	rogid:2bNoVkou3QatkNCtPIiSdvPdgEo559292	-	-	false	-	-	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:P32639	intact:EBI-10824938	intact:EBI-861|uniprotkb:D3DM80|ensemblfungi:YER172C	rnacentral:URS00006184A9_559292	psi-mi:brr2_yeast(display_long)|uniprotkb:BRR2(gene name)|psi-mi:BRR2(display_short)|uniprotkb:RSS1(gene name synonym)|uniprotkb:SNU246(gene name synonym)|uniprotkb:YER172C(locus name)|uniprotkb:SYGP-ORF66(orf name)|uniprotkb:Protein Snu246(gene name synonym)	psi-mi:snru6_yeast(display_short)|psi-mi:EBI-10824938(display_long)	psi-mi:"MI:0415"(enzymatic study)	Liu et al. (2014)	pubmed:26161500|imex:IM-25735	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0414"(enzymatic reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-15013424|imex:IM-25735-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0607"(small nuclear rna)	refseq:NP_011099.1|sgd:S000000974|dip:DIP-850N|mint:P32639|ensemblfungi:YER172C(gene)|ensemblfungi:YER172C_mRNA(transcript)|go:"GO:0000388"("spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)")|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0042802"(identical protein binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR004179(Sec63)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR027417|interpro:IPR035892|interpro:IPR036388|interpro:IPR036390|interpro:IPR041094|rcsb pdb:3HIB|rcsb pdb:3IM1|rcsb pdb:3IM2|rcsb pdb:3JCM|rcsb pdb:4BGD|rcsb pdb:5DCA|rcsb pdb:5GAN|rcsb pdb:5GAO|rcsb pdb:5GAP|rcsb pdb:5GM6|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5M52|rcsb pdb:5M5P|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:7B9V	-	-	crc64:DFAF7E3B7168D944	-	figure legend:Fig2A,B|comment:"The presence of Prp3 (296-469) inhibits the reaction"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/10/14	2017/05/28	rogid:2bNoVkou3QatkNCtPIiSdvPdgEo559292	-	-	false	-	-	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:Q03338	intact:EBI-10054797	intact:EBI-421|uniprotkb:D6VT97|ensemblfungi:YDR473C	rnacentral:URS00001143F5_559292	psi-mi:prp3_yeast(display_long)|uniprotkb:PRP3(gene name)|psi-mi:PRP3(display_short)|uniprotkb:RNA3(gene name synonym)|uniprotkb:YDR473C(locus name)|uniprotkb:D8035.16(orf name)|uniprotkb:Pre-mRNA-splicing factor 3(gene name synonym)	psi-mi:snr14_u4_yeast(display_short)|psi-mi:EBI-10054797(display_long)	psi-mi:"MI:0114"(x-ray crystallography)	Liu et al. (2014)	pubmed:26161500|imex:IM-25735	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-14060427|rcsb pdb:4YHW|imex:IM-25735-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0607"(small nuclear rna)	sgd:S000002881|refseq:NP_010761.3|ensemblfungi:YDR473C(gene)|ensemblfungi:YDR473C_mRNA(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|interpro:IPR010541(Protein of unknown function DUF1115)|interpro:IPR013881(Pre-mRNA-splicing factor 3)|interpro:IPR027104|rcsb pdb:3JCM|rcsb pdb:4YHU|rcsb pdb:4YHV|rcsb pdb:4YHW|rcsb pdb:5GAN|rcsb pdb:5GAP|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|dip:DIP-5266N|mint:Q03338	-	-	crc64:E977FD9F708BDD91	-	figure legend:Tab1, Fig 3,  Fig4|3d-r-factors:"R-Value Free: 0.299, R-Value Work: 0.249"|3d-resolution:3.25A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/10/14	2017/05/10	rogid:KE0Y/kRXTq9LXt4PGsKnRcY7Sqg559292	-	-	false	sufficient binding region:296-469	binding-associated region:1-17	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q03338	intact:EBI-10824938	intact:EBI-421|uniprotkb:D6VT97|ensemblfungi:YDR473C	rnacentral:URS00006184A9_559292	psi-mi:prp3_yeast(display_long)|uniprotkb:PRP3(gene name)|psi-mi:PRP3(display_short)|uniprotkb:RNA3(gene name synonym)|uniprotkb:YDR473C(locus name)|uniprotkb:D8035.16(orf name)|uniprotkb:Pre-mRNA-splicing factor 3(gene name synonym)	psi-mi:snru6_yeast(display_short)|psi-mi:EBI-10824938(display_long)	psi-mi:"MI:0114"(x-ray crystallography)	Liu et al. (2014)	pubmed:26161500|imex:IM-25735	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-14060427|rcsb pdb:4YHW|imex:IM-25735-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0607"(small nuclear rna)	sgd:S000002881|refseq:NP_010761.3|ensemblfungi:YDR473C(gene)|ensemblfungi:YDR473C_mRNA(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|interpro:IPR010541(Protein of unknown function DUF1115)|interpro:IPR013881(Pre-mRNA-splicing factor 3)|interpro:IPR027104|rcsb pdb:3JCM|rcsb pdb:4YHU|rcsb pdb:4YHV|rcsb pdb:4YHW|rcsb pdb:5GAN|rcsb pdb:5GAP|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|dip:DIP-5266N|mint:Q03338	-	-	crc64:E977FD9F708BDD91	-	figure legend:Tab1, Fig 3,  Fig4|3d-r-factors:"R-Value Free: 0.299, R-Value Work: 0.249"|3d-resolution:3.25A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/10/14	2017/05/10	rogid:KE0Y/kRXTq9LXt4PGsKnRcY7Sqg559292	-	-	false	sufficient binding region:296-469	binding-associated region:64-90	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q03338	uniprotkb:P36048	intact:EBI-421|uniprotkb:D6VT97|ensemblfungi:YDR473C	intact:EBI-243|uniprotkb:D6VX27|ensemblfungi:YKL173W	psi-mi:prp3_yeast(display_long)|uniprotkb:PRP3(gene name)|psi-mi:PRP3(display_short)|uniprotkb:RNA3(gene name synonym)|uniprotkb:YDR473C(locus name)|uniprotkb:D8035.16(orf name)|uniprotkb:Pre-mRNA-splicing factor 3(gene name synonym)	psi-mi:sn114_yeast(display_long)|uniprotkb:GIN10(gene name synonym)|uniprotkb:YKL173W(locus name)|uniprotkb:YKL637(orf name)|uniprotkb:SNU114(gene name)|psi-mi:SNU114(display_short)|uniprotkb:Growth inhibitory protein 10(gene name synonym)|uniprotkb:114 kDa U5 small nuclear ribonucleoprotein component(gene name synonym)	psi-mi:"MI:0027"(cosedimentation)	Liu et al. (2014)	pubmed:26161500|imex:IM-25735	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-14060674|imex:IM-25735-10	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002881|refseq:NP_010761.3|ensemblfungi:YDR473C(gene)|ensemblfungi:YDR473C_mRNA(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|interpro:IPR010541(Protein of unknown function DUF1115)|interpro:IPR013881(Pre-mRNA-splicing factor 3)|interpro:IPR027104|rcsb pdb:3JCM|rcsb pdb:4YHU|rcsb pdb:4YHV|rcsb pdb:4YHW|rcsb pdb:5GAN|rcsb pdb:5GAP|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|dip:DIP-5266N|mint:Q03338	refseq:NP_012748.1|sgd:S000001656|mint:P36048|dip:DIP-759N|ensemblfungi:YKL173W(gene)|ensemblfungi:YKL173W_mRNA(transcript)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000349"(generation of catalytic spliceosome for first transesterification step)|go:"GO:0000388"("spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)")|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005682"(U5 snRNP)|go:"GO:0030623"(U5 snRNA binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR005517(Translation elongation factor EFG/EF2, domain IV)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR020568|interpro:IPR027417|interpro:IPR031950|interpro:IPR035647|interpro:IPR035655|interpro:IPR044121|rcsb pdb:3JCM|rcsb pdb:5GAM|rcsb pdb:5GAN|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5NRL|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|rcsb pdb:6TEO	-	crc64:E977FD9F708BDD91	crc64:5CE30CEFF154D013	figure legend:Fig 5 C, D, E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2016/10/14	2017/05/10	rogid:KE0Y/kRXTq9LXt4PGsKnRcY7Sqg559292	rogid:eHDUPadk87+Qb525xpL1tMWb3S4559292	-	false	mutation decreasing interaction:304-304,322-322|mutation disrupting interaction:399-399,441-441	-	-	-	psi-mi:"MI:0929"(northern blot)	psi-mi:"MI:0929"(northern blot)
uniprotkb:Q03338	intact:EBI-10054797	intact:EBI-421|uniprotkb:D6VT97|ensemblfungi:YDR473C	rnacentral:URS00001143F5_559292	psi-mi:prp3_yeast(display_long)|uniprotkb:PRP3(gene name)|psi-mi:PRP3(display_short)|uniprotkb:RNA3(gene name synonym)|uniprotkb:YDR473C(locus name)|uniprotkb:D8035.16(orf name)|uniprotkb:Pre-mRNA-splicing factor 3(gene name synonym)	psi-mi:snr14_u4_yeast(display_short)|psi-mi:EBI-10054797(display_long)	psi-mi:"MI:0027"(cosedimentation)	Liu et al. (2014)	pubmed:26161500|imex:IM-25735	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-14060674|imex:IM-25735-10	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0607"(small nuclear rna)	sgd:S000002881|refseq:NP_010761.3|ensemblfungi:YDR473C(gene)|ensemblfungi:YDR473C_mRNA(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|interpro:IPR010541(Protein of unknown function DUF1115)|interpro:IPR013881(Pre-mRNA-splicing factor 3)|interpro:IPR027104|rcsb pdb:3JCM|rcsb pdb:4YHU|rcsb pdb:4YHV|rcsb pdb:4YHW|rcsb pdb:5GAN|rcsb pdb:5GAP|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|dip:DIP-5266N|mint:Q03338	-	-	crc64:E977FD9F708BDD91	-	figure legend:Fig 5 C, D, E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2016/10/14	2017/05/10	rogid:KE0Y/kRXTq9LXt4PGsKnRcY7Sqg559292	-	-	false	mutation decreasing interaction:304-304,322-322|mutation disrupting interaction:399-399,441-441	-	-	-	psi-mi:"MI:0929"(northern blot)	psi-mi:"MI:0929"(northern blot)
uniprotkb:Q03338	intact:EBI-10054803	intact:EBI-421|uniprotkb:D6VT97|ensemblfungi:YDR473C	rnacentral:URS000053F313_559292	psi-mi:prp3_yeast(display_long)|uniprotkb:PRP3(gene name)|psi-mi:PRP3(display_short)|uniprotkb:RNA3(gene name synonym)|uniprotkb:YDR473C(locus name)|uniprotkb:D8035.16(orf name)|uniprotkb:Pre-mRNA-splicing factor 3(gene name synonym)	psi-mi:snr7l_yeast_ncrna(display_short)|psi-mi:EBI-10054803(display_long)	psi-mi:"MI:0027"(cosedimentation)	Liu et al. (2014)	pubmed:26161500|imex:IM-25735	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-14060674|imex:IM-25735-10	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0607"(small nuclear rna)	sgd:S000002881|refseq:NP_010761.3|ensemblfungi:YDR473C(gene)|ensemblfungi:YDR473C_mRNA(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|interpro:IPR010541(Protein of unknown function DUF1115)|interpro:IPR013881(Pre-mRNA-splicing factor 3)|interpro:IPR027104|rcsb pdb:3JCM|rcsb pdb:4YHU|rcsb pdb:4YHV|rcsb pdb:4YHW|rcsb pdb:5GAN|rcsb pdb:5GAP|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|dip:DIP-5266N|mint:Q03338	-	-	crc64:E977FD9F708BDD91	-	figure legend:Fig 5 C, D, E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2016/10/14	2017/05/10	rogid:KE0Y/kRXTq9LXt4PGsKnRcY7Sqg559292	-	-	false	mutation decreasing interaction:304-304,322-322|mutation disrupting interaction:399-399,441-441	-	-	-	psi-mi:"MI:0929"(northern blot)	psi-mi:"MI:0929"(northern blot)
uniprotkb:Q03338	intact:EBI-10825220	intact:EBI-421|uniprotkb:D6VT97|ensemblfungi:YDR473C	rnacentral:URS0000514318_559292	psi-mi:prp3_yeast(display_long)|uniprotkb:PRP3(gene name)|psi-mi:PRP3(display_short)|uniprotkb:RNA3(gene name synonym)|uniprotkb:YDR473C(locus name)|uniprotkb:D8035.16(orf name)|uniprotkb:Pre-mRNA-splicing factor 3(gene name synonym)	psi-mi:snr7s_u5_yeast(display_short)|psi-mi:EBI-10825220(display_long)	psi-mi:"MI:0027"(cosedimentation)	Liu et al. (2014)	pubmed:26161500|imex:IM-25735	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-14060674|imex:IM-25735-10	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0607"(small nuclear rna)	sgd:S000002881|refseq:NP_010761.3|ensemblfungi:YDR473C(gene)|ensemblfungi:YDR473C_mRNA(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|interpro:IPR010541(Protein of unknown function DUF1115)|interpro:IPR013881(Pre-mRNA-splicing factor 3)|interpro:IPR027104|rcsb pdb:3JCM|rcsb pdb:4YHU|rcsb pdb:4YHV|rcsb pdb:4YHW|rcsb pdb:5GAN|rcsb pdb:5GAP|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|dip:DIP-5266N|mint:Q03338	-	-	crc64:E977FD9F708BDD91	-	figure legend:Fig 5 C, D, E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2016/10/14	2017/05/10	rogid:KE0Y/kRXTq9LXt4PGsKnRcY7Sqg559292	-	-	false	mutation decreasing interaction:304-304,322-322|mutation disrupting interaction:399-399,441-441	-	-	-	psi-mi:"MI:0929"(northern blot)	psi-mi:"MI:0929"(northern blot)
uniprotkb:Q03338	intact:EBI-10824938	intact:EBI-421|uniprotkb:D6VT97|ensemblfungi:YDR473C	rnacentral:URS00006184A9_559292	psi-mi:prp3_yeast(display_long)|uniprotkb:PRP3(gene name)|psi-mi:PRP3(display_short)|uniprotkb:RNA3(gene name synonym)|uniprotkb:YDR473C(locus name)|uniprotkb:D8035.16(orf name)|uniprotkb:Pre-mRNA-splicing factor 3(gene name synonym)	psi-mi:snru6_yeast(display_short)|psi-mi:EBI-10824938(display_long)	psi-mi:"MI:0027"(cosedimentation)	Liu et al. (2014)	pubmed:26161500|imex:IM-25735	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-14060674|imex:IM-25735-10	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0607"(small nuclear rna)	sgd:S000002881|refseq:NP_010761.3|ensemblfungi:YDR473C(gene)|ensemblfungi:YDR473C_mRNA(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|interpro:IPR010541(Protein of unknown function DUF1115)|interpro:IPR013881(Pre-mRNA-splicing factor 3)|interpro:IPR027104|rcsb pdb:3JCM|rcsb pdb:4YHU|rcsb pdb:4YHV|rcsb pdb:4YHW|rcsb pdb:5GAN|rcsb pdb:5GAP|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|dip:DIP-5266N|mint:Q03338	-	-	crc64:E977FD9F708BDD91	-	figure legend:Fig 5 C, D, E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2016/10/14	2017/05/10	rogid:KE0Y/kRXTq9LXt4PGsKnRcY7Sqg559292	-	-	false	mutation decreasing interaction:304-304,322-322|mutation disrupting interaction:399-399,441-441	-	-	-	psi-mi:"MI:0929"(northern blot)	psi-mi:"MI:0929"(northern blot)