#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P00740	uniprotkb:P00451-PRO_0000002968	intact:EBI-9640450|uniprotkb:A8K9N4|uniprotkb:Q5JYJ8|uniprotkb:F2RM36|uniprotkb:Q5FBE1|ensembl:ENSP00000218099	intact:EBI-11621603	psi-mi:fa9_human(display_long)|uniprotkb:F9(gene name)|psi-mi:F9(display_short)|uniprotkb:Christmas factor(gene name synonym)|uniprotkb:Plasma thromboplastin component(gene name synonym)	psi-mi:p00451-pro_0000002968(display_long)|uniprotkb:Antihemophilic factor(gene name synonym)|uniprotkb:Procoagulant component(gene name synonym)|uniprotkb:F8(gene name)|psi-mi:F8(display_short)|uniprotkb:F8C(gene name synonym)	psi-mi:"MI:0096"(pull down)	Choi et al. (2015)	pubmed:26157780|imex:IM-25809	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11621595|imex:IM-25809-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001300842.1|refseq:NP_000124.1|dip:DIP-58520N|ensembl:ENSG00000101981(gene)|ensembl:ENST00000218099(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0007596"(blood coagulation)|go:"GO:0031638"(zymogen activation)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000294(Vitamin K-dependent carboxylation/gamma-carboxyglutamic region)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR012224(Peptidase S1A, coagulation factor VII/IX/X/C/Z)|interpro:IPR017857(Coagulation factor, subset, Gla region)|interpro:IPR018097|interpro:IPR018114|interpro:IPR033116|interpro:IPR035694|interpro:IPR035972|interpro:IPR043504|rcsb pdb:1CFH|rcsb pdb:1CFI|rcsb pdb:1EDM|rcsb pdb:1IXA|rcsb pdb:1MGX|rcsb pdb:1NL0|rcsb pdb:1RFN|rcsb pdb:2WPH|rcsb pdb:2WPI|rcsb pdb:2WPJ|rcsb pdb:2WPK|rcsb pdb:2WPL|rcsb pdb:2WPM|rcsb pdb:3KCG|rcsb pdb:3LC3|rcsb pdb:3LC5|rcsb pdb:4WM0|rcsb pdb:4WMA|rcsb pdb:4WMB|rcsb pdb:4WMI|rcsb pdb:4WMK|rcsb pdb:4WN2|rcsb pdb:4WNH|rcsb pdb:4YZU|rcsb pdb:4Z0K|rcsb pdb:4ZAE|rcsb pdb:5EGM|rcsb pdb:5F84|rcsb pdb:5F85|rcsb pdb:5F86|rcsb pdb:5JB8|rcsb pdb:5JB9|rcsb pdb:5JBA|rcsb pdb:5JBB|rcsb pdb:5JBC|rcsb pdb:5TNO|rcsb pdb:5TNT|rcsb pdb:5VYG|rcsb pdb:6MV4|rcsb pdb:6RFK|rcsb pdb:6X5J|rcsb pdb:6X5L|rcsb pdb:6X5P|reactome:R-HSA-140834|reactome:R-HSA-140837|reactome:R-HSA-159740|reactome:R-HSA-159763|reactome:R-HSA-159782|reactome:R-HSA-9672383|reactome:R-HSA-9672396|reactome:R-HSA-9673202|reactome:R-HSA-9673218|reactome:R-HSA-9673221|reactome:R-HSA-9673240|mint:P00740	intact:EBI-1046394(chain-parent)	-	-	chain-seq-start:20|chain-seq-end:1332	figure legend:Fig. 3A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/03/14	2017/07/31	rogid:WgF6aC2nvjTyYTwIhMpWd2paXgI9606	rogid:XEktBmbZJjcV5tbgGTyQ9IsIUDQ9606	rigid:Hvowan/p+rCGGN7cgkuVsdCn/UY	false	-	sufficient binding region:387-587|glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P00740	uniprotkb:P00451-PRO_0000002968	intact:EBI-9640450|uniprotkb:A8K9N4|uniprotkb:Q5JYJ8|uniprotkb:F2RM36|uniprotkb:Q5FBE1|ensembl:ENSP00000218099	intact:EBI-11621603	psi-mi:fa9_human(display_long)|uniprotkb:F9(gene name)|psi-mi:F9(display_short)|uniprotkb:Christmas factor(gene name synonym)|uniprotkb:Plasma thromboplastin component(gene name synonym)	psi-mi:p00451-pro_0000002968(display_long)|uniprotkb:Antihemophilic factor(gene name synonym)|uniprotkb:Procoagulant component(gene name synonym)|uniprotkb:F8(gene name)|psi-mi:F8(display_short)|uniprotkb:F8C(gene name synonym)	psi-mi:"MI:0096"(pull down)	Choi et al. (2015)	pubmed:26157780|imex:IM-25809	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11621615|imex:IM-25809-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001300842.1|refseq:NP_000124.1|dip:DIP-58520N|ensembl:ENSG00000101981(gene)|ensembl:ENST00000218099(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0007596"(blood coagulation)|go:"GO:0031638"(zymogen activation)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000294(Vitamin K-dependent carboxylation/gamma-carboxyglutamic region)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR012224(Peptidase S1A, coagulation factor VII/IX/X/C/Z)|interpro:IPR017857(Coagulation factor, subset, Gla region)|interpro:IPR018097|interpro:IPR018114|interpro:IPR033116|interpro:IPR035694|interpro:IPR035972|interpro:IPR043504|rcsb pdb:1CFH|rcsb pdb:1CFI|rcsb pdb:1EDM|rcsb pdb:1IXA|rcsb pdb:1MGX|rcsb pdb:1NL0|rcsb pdb:1RFN|rcsb pdb:2WPH|rcsb pdb:2WPI|rcsb pdb:2WPJ|rcsb pdb:2WPK|rcsb pdb:2WPL|rcsb pdb:2WPM|rcsb pdb:3KCG|rcsb pdb:3LC3|rcsb pdb:3LC5|rcsb pdb:4WM0|rcsb pdb:4WMA|rcsb pdb:4WMB|rcsb pdb:4WMI|rcsb pdb:4WMK|rcsb pdb:4WN2|rcsb pdb:4WNH|rcsb pdb:4YZU|rcsb pdb:4Z0K|rcsb pdb:4ZAE|rcsb pdb:5EGM|rcsb pdb:5F84|rcsb pdb:5F85|rcsb pdb:5F86|rcsb pdb:5JB8|rcsb pdb:5JB9|rcsb pdb:5JBA|rcsb pdb:5JBB|rcsb pdb:5JBC|rcsb pdb:5TNO|rcsb pdb:5TNT|rcsb pdb:5VYG|rcsb pdb:6MV4|rcsb pdb:6RFK|rcsb pdb:6X5J|rcsb pdb:6X5L|rcsb pdb:6X5P|reactome:R-HSA-140834|reactome:R-HSA-140837|reactome:R-HSA-159740|reactome:R-HSA-159763|reactome:R-HSA-159782|reactome:R-HSA-9672383|reactome:R-HSA-9672396|reactome:R-HSA-9673202|reactome:R-HSA-9673218|reactome:R-HSA-9673221|reactome:R-HSA-9673240|mint:P00740	intact:EBI-1046394(chain-parent)	-	-	chain-seq-start:20|chain-seq-end:1332	figure legend:Fig. 3B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/03/14	2016/03/14	rogid:WgF6aC2nvjTyYTwIhMpWd2paXgI9606	rogid:XEktBmbZJjcV5tbgGTyQ9IsIUDQ9606	rigid:Hvowan/p+rCGGN7cgkuVsdCn/UY	false	-	sufficient binding region:387-587|glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)