#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:A1L3G9 uniprotkb:P50402 intact:EBI-12596203|uniprotkb:B9X188 intact:EBI-489887|uniprotkb:Q6FI02|ensembl:ENSP00000358857|ensembl:ENSP00000507533 psi-mi:nmp1b_xenla(display_long)|uniprotkb:nemp1b(gene name)|psi-mi:nemp1b(display_short)|uniprotkb:tmem194a-b(gene name synonym) psi-mi:emd_human(display_long)|uniprotkb:EDMD(gene name synonym)|uniprotkb:STA(gene name synonym)|uniprotkb:EMD(gene name)|psi-mi:EMD(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Shibano et al. (2014) pubmed:25946333|imex:IM-25595 taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-12595918|imex:IM-25595-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0001654"(eye development)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043621"(protein self-association)|refseq:NP_001091224.1|interpro:IPR019358 refseq:NP_000108.1|ensembl:ENSP00000358857|ensembl:ENSP00000507533|ensembl:ENSG00000102119(gene)|ensembl:ENST00000369842(transcript)|ensembl:ENST00000683627(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006936"(muscle contraction)|go:"GO:0007517"(muscle organ development)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0045296"(cadherin binding)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071763"(nuclear membrane organization)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR011015(LEM-like fold)|interpro:IPR034989|interpro:IPR035004|mint:P50402|rcsb pdb:1JEI|rcsb pdb:2ODC|rcsb pdb:2ODG|rcsb pdb:6GHD|rcsb pdb:6RPR|rcsb pdb:7NDY|reactome:R-HSA-2980766|reactome:R-HSA-2995383|reactome:R-HSA-4419969|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9609523|interpro:IPR003887(Lamino-associated polypeptide 2/emerin)|dip:DIP-34638N - - - figure legend:2A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:8355(xenla-embryo)|taxid:8355(Xenopus laevis embryo) - 2016/11/09 2016/11/10 rogid:5zQ8cK1+BSsQ0gFdbod42zTTA+w8355 rogid:hqH2sFjAGwjIGtGX/rjVVFgaYsE9606 rigid:zXpA+TceolzfzdWTuRAGi/r3qTY false ha tag:c-c myc tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P62827 uniprotkb:Q6ZQE4 intact:EBI-286564|uniprotkb:Q3U954|uniprotkb:Q811M2|uniprotkb:Q86V08|uniprotkb:P17080|uniprotkb:P28746|uniprotkb:P28747|uniprotkb:Q9UDJ5|uniprotkb:Q9CSP3|uniprotkb:Q9CWI7|uniprotkb:Q9CZA2|uniprotkb:Q9UEU9|ensembl:ENSMUSP00000031383|ensembl:ENSMUSP00000106975 intact:EBI-12595939|ensembl:ENSMUSP00000045988 psi-mi:ran_mouse(display_long)|uniprotkb:GTPase Ran(gene name synonym)|uniprotkb:Ras-related nuclear protein(gene name synonym)|uniprotkb:Ras-like protein TC4(gene name synonym)|uniprotkb:Ran(gene name)|psi-mi:Ran(display_short)|uniprotkb:Rasl2-8(gene name synonym) psi-mi:nemp1_mouse(display_long)|uniprotkb:Nemp1(gene name)|psi-mi:Nemp1(display_short)|uniprotkb:Kiaa0286(gene name synonym)|uniprotkb:Tmem194(gene name synonym)|uniprotkb:Tmem194a(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Shibano et al. (2014) pubmed:25946333|imex:IM-25595 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-12595973|imex:IM-25595-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033417.1|refseq:XP_006504343.1|ensembl:ENSMUSG00000029430(gene)|ensembl:ENSMUST00000031383(transcript)|ensembl:ENSMUST00000111343(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0002177"(manchette)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0019003"(GDP binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030496"(midbody)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034629"|go:"GO:0036126"(sperm flagellum)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042470"(melanosome)|go:"GO:0042565"(RNA nuclear export complex)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0046039"(GTP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:0055037"(recycling endosome)|go:"GO:0061015"(snRNA import into nucleus)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:1902570"(protein localization to nucleolus)|interpro:IPR001806(Ras GTPase)|interpro:IPR002041(Ran GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P62827|reactome:R-MMU-1655829|reactome:R-MMU-5578749|reactome:R-MMU-9615933 ensembl:ENSMUSG00000040195(gene)|ensembl:ENSMUST00000048099(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071763"(nuclear membrane organization)|interpro:IPR019358|refseq:NP_001106682.1 - - - figure legend:3B and E, 5A, S3, 6D, 9B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:8355(xenla-embryo)|taxid:8355(Xenopus laevis embryo) - 2016/11/09 2016/11/09 rogid:trIUv5n3nI5d0rkfDTgw/6ubxMA10090 rogid:XDNP6V5SG9TAWLDem6X/Pq+zofY10090 rigid:giD7AgA+VlUngCIQXRljf8+NO7k false mutation disrupting interaction strength:42-42|sufficient binding region:1-210|myc tag:n-n|mutation with no effect:69-69|mutation disrupting interaction strength:24-24 mutation disrupting interaction strength:366-366,376-376,380-380,419-419,420-420|ha tag:c-c|mutation disrupting interaction strength:420-420,366-366,376-376,380-380,419-419|sufficient binding region:334-437 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P62827 uniprotkb:Q6ZQE4 intact:EBI-286564|uniprotkb:Q3U954|uniprotkb:Q811M2|uniprotkb:Q86V08|uniprotkb:P17080|uniprotkb:P28746|uniprotkb:P28747|uniprotkb:Q9UDJ5|uniprotkb:Q9CSP3|uniprotkb:Q9CWI7|uniprotkb:Q9CZA2|uniprotkb:Q9UEU9|ensembl:ENSMUSP00000031383|ensembl:ENSMUSP00000106975 intact:EBI-12595939|ensembl:ENSMUSP00000045988 psi-mi:ran_mouse(display_long)|uniprotkb:GTPase Ran(gene name synonym)|uniprotkb:Ras-related nuclear protein(gene name synonym)|uniprotkb:Ras-like protein TC4(gene name synonym)|uniprotkb:Ran(gene name)|psi-mi:Ran(display_short)|uniprotkb:Rasl2-8(gene name synonym) psi-mi:nemp1_mouse(display_long)|uniprotkb:Nemp1(gene name)|psi-mi:Nemp1(display_short)|uniprotkb:Kiaa0286(gene name synonym)|uniprotkb:Tmem194(gene name synonym)|uniprotkb:Tmem194a(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Shibano et al. (2014) pubmed:25946333|imex:IM-25595 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-12596056|imex:IM-25595-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033417.1|refseq:XP_006504343.1|ensembl:ENSMUSG00000029430(gene)|ensembl:ENSMUST00000031383(transcript)|ensembl:ENSMUST00000111343(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0002177"(manchette)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0019003"(GDP binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030496"(midbody)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034629"|go:"GO:0036126"(sperm flagellum)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042470"(melanosome)|go:"GO:0042565"(RNA nuclear export complex)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0046039"(GTP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:0055037"(recycling endosome)|go:"GO:0061015"(snRNA import into nucleus)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:1902570"(protein localization to nucleolus)|interpro:IPR001806(Ras GTPase)|interpro:IPR002041(Ran GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P62827|reactome:R-MMU-1655829|reactome:R-MMU-5578749|reactome:R-MMU-9615933 ensembl:ENSMUSG00000040195(gene)|ensembl:ENSMUST00000048099(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071763"(nuclear membrane organization)|interpro:IPR019358|refseq:NP_001106682.1 - - - figure legend:4A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:8355(xenla-embryo)|taxid:8355(Xenopus laevis embryo) - 2016/11/09 2016/11/09 rogid:trIUv5n3nI5d0rkfDTgw/6ubxMA10090 rogid:XDNP6V5SG9TAWLDem6X/Pq+zofY10090 rigid:giD7AgA+VlUngCIQXRljf8+NO7k false myc tag:c-c ha tag:c-c|sufficient binding region:334-403|green fluorescent protein tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P52301 uniprotkb:B9X187 intact:EBI-12596079|uniprotkb:Q7ZYT6|uniprotkb:Q9IBE8 intact:EBI-12595897|uniprotkb:Q0IH41 psi-mi:ran_xenla(display_long)|uniprotkb:ran(gene name)|psi-mi:ran(display_short)|uniprotkb:GTPase Ran(gene name synonym)|uniprotkb:Ras-like protein TC4(gene name synonym)|uniprotkb:Ras-related nuclear protein(gene name synonym) psi-mi:nmp1a_xenla(display_long)|uniprotkb:nemp1a(gene name)|psi-mi:nemp1a(display_short)|uniprotkb:tmem194a-a(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Shibano et al. (2014) pubmed:25946333|imex:IM-25595 taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-12596100|imex:IM-25595-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001654"(eye development)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0046039"(GTP metabolic process)|go:"GO:0061015"(snRNA import into nucleus)|refseq:XP_018089010.1|refseq:XP_018089018.1|refseq:XP_018117934.1|refseq:XP_018117939.1|refseq:NP_001080182.1|refseq:NP_001128547.1|interpro:IPR027417|interpro:IPR002041(Ran GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR001806(Ras GTPase) go:"GO:0001654"(eye development)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043621"(protein self-association)|refseq:NP_001090391.1|interpro:IPR019358 - - - figure legend:4B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:8355(xenla-embryo)|taxid:8355(Xenopus laevis embryo) - 2016/11/09 2016/11/09 rogid:6f74s0tt6qNSVKKfKREBexke/sU8355 rogid:BR+SqadfH6FBNh9xeDO5bB1wctU8355 rigid:waDsSiV+In5v9lqHE7xENIMWyTw false myc tag:n-n ha tag:c-c|necessary binding region:368-375|sufficient binding region:326-434|green fluorescent protein tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P41917 uniprotkb:Q9SHQ6 intact:EBI-2325919|uniprotkb:Q0WVD9|uniprotkb:Q94K33|ensemblplants:AT5G20020.1 intact:EBI-12596158|ensemblplants:AT1G28760.1 psi-mi:ran2_arath(display_long)|uniprotkb:RAN2(gene name)|psi-mi:RAN2(display_short)|uniprotkb:Ras-related nuclear protein 2(gene name synonym)|uniprotkb:F28I16.170(orf name)|uniprotkb:At5g20020(locus name) psi-mi:q9shq6_arath(display_long)|uniprotkb:F1K23.6(orf name)|uniprotkb:F1K23_6(orf name)|uniprotkb:At1g28760(locus name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Shibano et al. (2014) pubmed:25946333|imex:IM-25595 taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)") taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-12596165|imex:IM-25595-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_197502.1|interpro:IPR002041(Ran GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR027417|ensemblplants:AT5G20020(gene)|ensemblplants:AT5G20020.1(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0003729"(mRNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0009536"(plastid)|go:"GO:0046686"(response to cadmium ion) ensemblplants:AT1G28760(gene)|ensemblplants:AT1G28760.1(transcript)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0071456"(cellular response to hypoxia)|refseq:NP_174193.2|interpro:IPR019358 - - - figure legend:9A and B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:8355(xenla-embryo)|taxid:8355(Xenopus laevis embryo) - 2016/11/09 2016/11/09 rogid:yd0gTLraKe6p6Tj469g8KSebQFM3702 rogid:M46NuaHVvD5qd1eqEJGCEtGbYF83702 rigid:rq0HcuJDcImh+BSnd0TPSSej6AQ false myc tag:n-n green fluorescent protein tag:n-n|ha tag:c-c|sufficient binding region:319-476 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:F4K567 uniprotkb:P41917 intact:EBI-12596182|ensemblplants:AT5G67610.2 intact:EBI-2325919|uniprotkb:Q0WVD9|uniprotkb:Q94K33|ensemblplants:AT5G20020.1 psi-mi:f4k567_arath(display_long)|uniprotkb:K9I9.18(orf name)|uniprotkb:K9I9_18(orf name)|uniprotkb:At5g67610(locus name) psi-mi:ran2_arath(display_long)|uniprotkb:RAN2(gene name)|psi-mi:RAN2(display_short)|uniprotkb:Ras-related nuclear protein 2(gene name synonym)|uniprotkb:F28I16.170(orf name)|uniprotkb:At5g20020(locus name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Shibano et al. (2014) pubmed:25946333|imex:IM-25595 taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)") taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-12596177|imex:IM-25595-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblplants:AT5G67610(gene)|ensemblplants:AT5G67610.2(transcript)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0016021"(integral component of membrane)|refseq:NP_001032168.1|interpro:IPR019358 refseq:NP_197502.1|interpro:IPR002041(Ran GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR027417|ensemblplants:AT5G20020(gene)|ensemblplants:AT5G20020.1(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0003729"(mRNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0009536"(plastid)|go:"GO:0046686"(response to cadmium ion) - - - figure legend:9A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:8355(xenla-embryo)|taxid:8355(Xenopus laevis embryo) - 2016/11/09 2016/11/09 rogid:RYxtA94fXrcLQI553xC47sdxq083702 rogid:yd0gTLraKe6p6Tj469g8KSebQFM3702 rigid:GqnQrS0X01OgyHN7S5mo7SVthII false green fluorescent protein tag:n-n|ha tag:c-c|sufficient binding region:344-498 myc tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:A1L3G9 uniprotkb:B9X187 intact:EBI-12596203|uniprotkb:B9X188 intact:EBI-12595897|uniprotkb:Q0IH41 psi-mi:nmp1b_xenla(display_long)|uniprotkb:nemp1b(gene name)|psi-mi:nemp1b(display_short)|uniprotkb:tmem194a-b(gene name synonym) psi-mi:nmp1a_xenla(display_long)|uniprotkb:nemp1a(gene name)|psi-mi:nemp1a(display_short)|uniprotkb:tmem194a-a(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Shibano et al. (2014) pubmed:25946333|imex:IM-25595 taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-12597651|imex:IM-25595-12 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0001654"(eye development)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043621"(protein self-association)|refseq:NP_001091224.1|interpro:IPR019358 go:"GO:0001654"(eye development)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043621"(protein self-association)|refseq:NP_001090391.1|interpro:IPR019358 - - - figure legend:2A and B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:8355(xenla-embryo)|taxid:8355(Xenopus laevis embryo) - 2016/11/09 2016/11/14 rogid:5zQ8cK1+BSsQ0gFdbod42zTTA+w8355 rogid:BR+SqadfH6FBNh9xeDO5bB1wctU8355 rigid:cNsSUMdYNk7mlUjy6ESLAvNUm2I false ha tag:c-c myc tag:c-c|sufficient binding region:1-36,176-287 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q7ZTB4 uniprotkb:A1L3G9 intact:EBI-12596361 intact:EBI-12596203|uniprotkb:B9X188 psi-mi:q7ztb4_xenla(display_long)|uniprotkb:lemd3.S(gene name)|psi-mi:lemd3.S(display_short)|uniprotkb:XMAN1(gene name synonym)|uniprotkb:lemd3(gene name synonym) psi-mi:nmp1b_xenla(display_long)|uniprotkb:nemp1b(gene name)|psi-mi:nemp1b(display_short)|uniprotkb:tmem194a-b(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Shibano et al. (2014) pubmed:25946333|imex:IM-25595 taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-12599203|imex:IM-25595-14 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003676"(nucleic acid binding)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0006997"(nucleus organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:1902531"(regulation of intracellular signal transduction)|interpro:IPR041885|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|refseq:NP_001082578.1|interpro:IPR018996|interpro:IPR011015(LEM-like fold)|interpro:IPR003887(Lamino-associated polypeptide 2/emerin)|interpro:IPR034394|interpro:IPR034997|interpro:IPR035979 go:"GO:0001654"(eye development)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043621"(protein self-association)|refseq:NP_001091224.1|interpro:IPR019358 - - - figure legend:2A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:8355(xenla-embryo)|taxid:8355(Xenopus laevis embryo) - 2016/11/09 2016/11/18 rogid:F8+p8vfvvl6kNnalsshRzIyp8rQ8355 rogid:5zQ8cK1+BSsQ0gFdbod42zTTA+w8355 rigid:G7iv3W54jw5WWw+jeUaWtOSgjH8 false myc tag:?-? ha tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P62827 uniprotkb:Q6ZQE4 intact:EBI-286564|uniprotkb:Q3U954|uniprotkb:Q811M2|uniprotkb:Q86V08|uniprotkb:P17080|uniprotkb:P28746|uniprotkb:P28747|uniprotkb:Q9UDJ5|uniprotkb:Q9CSP3|uniprotkb:Q9CWI7|uniprotkb:Q9CZA2|uniprotkb:Q9UEU9|ensembl:ENSMUSP00000031383|ensembl:ENSMUSP00000106975 intact:EBI-12595939|ensembl:ENSMUSP00000045988 psi-mi:ran_mouse(display_long)|uniprotkb:GTPase Ran(gene name synonym)|uniprotkb:Ras-related nuclear protein(gene name synonym)|uniprotkb:Ras-like protein TC4(gene name synonym)|uniprotkb:Ran(gene name)|psi-mi:Ran(display_short)|uniprotkb:Rasl2-8(gene name synonym) psi-mi:nemp1_mouse(display_long)|uniprotkb:Nemp1(gene name)|psi-mi:Nemp1(display_short)|uniprotkb:Kiaa0286(gene name synonym)|uniprotkb:Tmem194(gene name synonym)|uniprotkb:Tmem194a(gene name synonym) psi-mi:"MI:0018"(two hybrid) Shibano et al. (2014) pubmed:25946333|imex:IM-25595 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-12595954|imex:IM-25595-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033417.1|refseq:XP_006504343.1|ensembl:ENSMUSG00000029430(gene)|ensembl:ENSMUST00000031383(transcript)|ensembl:ENSMUST00000111343(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0002177"(manchette)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0019003"(GDP binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030496"(midbody)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034629"|go:"GO:0036126"(sperm flagellum)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042470"(melanosome)|go:"GO:0042565"(RNA nuclear export complex)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0046039"(GTP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:0055037"(recycling endosome)|go:"GO:0061015"(snRNA import into nucleus)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:1902570"(protein localization to nucleolus)|interpro:IPR001806(Ras GTPase)|interpro:IPR002041(Ran GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P62827|reactome:R-MMU-1655829|reactome:R-MMU-5578749|reactome:R-MMU-9615933 ensembl:ENSMUSG00000040195(gene)|ensembl:ENSMUST00000048099(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071763"(nuclear membrane organization)|interpro:IPR019358|refseq:NP_001106682.1 - - - figure legend:3A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2016/11/09 2016/11/09 rogid:trIUv5n3nI5d0rkfDTgw/6ubxMA10090 rogid:XDNP6V5SG9TAWLDem6X/Pq+zofY10090 rigid:giD7AgA+VlUngCIQXRljf8+NO7k false - sufficient binding region:334-437 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P62827 uniprotkb:Q6ZQE4 intact:EBI-286564|uniprotkb:Q3U954|uniprotkb:Q811M2|uniprotkb:Q86V08|uniprotkb:P17080|uniprotkb:P28746|uniprotkb:P28747|uniprotkb:Q9UDJ5|uniprotkb:Q9CSP3|uniprotkb:Q9CWI7|uniprotkb:Q9CZA2|uniprotkb:Q9UEU9|ensembl:ENSMUSP00000031383|ensembl:ENSMUSP00000106975 intact:EBI-12595939|ensembl:ENSMUSP00000045988 psi-mi:ran_mouse(display_long)|uniprotkb:GTPase Ran(gene name synonym)|uniprotkb:Ras-related nuclear protein(gene name synonym)|uniprotkb:Ras-like protein TC4(gene name synonym)|uniprotkb:Ran(gene name)|psi-mi:Ran(display_short)|uniprotkb:Rasl2-8(gene name synonym) psi-mi:nemp1_mouse(display_long)|uniprotkb:Nemp1(gene name)|psi-mi:Nemp1(display_short)|uniprotkb:Kiaa0286(gene name synonym)|uniprotkb:Tmem194(gene name synonym)|uniprotkb:Tmem194a(gene name synonym) psi-mi:"MI:0018"(two hybrid) Shibano et al. (2014) pubmed:25946333|imex:IM-25595 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-12595966|imex:IM-25595-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033417.1|refseq:XP_006504343.1|ensembl:ENSMUSG00000029430(gene)|ensembl:ENSMUST00000031383(transcript)|ensembl:ENSMUST00000111343(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0002177"(manchette)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0019003"(GDP binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030496"(midbody)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034629"|go:"GO:0036126"(sperm flagellum)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042470"(melanosome)|go:"GO:0042565"(RNA nuclear export complex)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0046039"(GTP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:0055037"(recycling endosome)|go:"GO:0061015"(snRNA import into nucleus)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:1902570"(protein localization to nucleolus)|interpro:IPR001806(Ras GTPase)|interpro:IPR002041(Ran GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P62827|reactome:R-MMU-1655829|reactome:R-MMU-5578749|reactome:R-MMU-9615933 ensembl:ENSMUSG00000040195(gene)|ensembl:ENSMUST00000048099(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071763"(nuclear membrane organization)|interpro:IPR019358|refseq:NP_001106682.1 - - - figure legend:no figure|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2016/11/09 2016/11/09 rogid:trIUv5n3nI5d0rkfDTgw/6ubxMA10090 rogid:XDNP6V5SG9TAWLDem6X/Pq+zofY10090 rigid:giD7AgA+VlUngCIQXRljf8+NO7k false - sufficient binding region:334-437 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P63280 uniprotkb:Q6ZQE4 intact:EBI-80180|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q6RUT3|uniprotkb:Q86VB3|ensembl:ENSMUSP00000055714|ensembl:ENSMUSP00000134169|ensembl:ENSMUSP00000134261|ensembl:ENSMUSP00000134350|ensembl:ENSMUSP00000134450|ensembl:ENSMUSP00000134491 intact:EBI-12595939|ensembl:ENSMUSP00000045988 psi-mi:ubc9_mouse(display_long)|uniprotkb:Ube2i(gene name)|psi-mi:Ube2i(display_short)|uniprotkb:Ubc9(gene name synonym)|uniprotkb:Ubce9(gene name synonym)|uniprotkb:Ubce2i(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym) psi-mi:nemp1_mouse(display_long)|uniprotkb:Nemp1(gene name)|psi-mi:Nemp1(display_short)|uniprotkb:Kiaa0286(gene name synonym)|uniprotkb:Tmem194(gene name synonym)|uniprotkb:Tmem194a(gene name synonym) psi-mi:"MI:0018"(two hybrid) Shibano et al. (2014) pubmed:25946333|imex:IM-25595 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-12598469|imex:IM-25595-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001171080.1|refseq:NP_001171081.1|refseq:NP_035795.1|ensembl:ENSMUSG00000015120(gene)|ensembl:ENSMUST00000049911(transcript)|ensembl:ENSMUST00000172618(transcript)|ensembl:ENSMUST00000173084(transcript)|ensembl:ENSMUST00000173713(transcript)|ensembl:ENSMUST00000174001(transcript)|ensembl:ENSMUST00000174031(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001650"(fibrillar center)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010469"(regulation of signaling receptor activity)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030425"(dendrite)|go:"GO:0033145"(positive regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043398"(HLH domain binding)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045202"(synapse)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990234"(transferase complex)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63280|rcsb pdb:1U9A|rcsb pdb:1U9B|rcsb pdb:2UYZ|rcsb pdb:2VRR|reactome:R-MMU-196791|reactome:R-MMU-3065678|reactome:R-MMU-3108214|reactome:R-MMU-3108232|reactome:R-MMU-3232118|reactome:R-MMU-3232142|reactome:R-MMU-3899300|reactome:R-MMU-4085377|reactome:R-MMU-4090294|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-4615885|reactome:R-MMU-4655427|reactome:R-MMU-4755510|reactome:R-MMU-5693565|reactome:R-MMU-5693607|reactome:R-MMU-5696395|reactome:R-MMU-8866904|reactome:R-MMU-9615933|refseq:XP_006524111.1|refseq:XP_006524112.1|dip:DIP-29276N ensembl:ENSMUSG00000040195(gene)|ensembl:ENSMUST00000048099(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071763"(nuclear membrane organization)|interpro:IPR019358|refseq:NP_001106682.1 - - - figure legend:no figure|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2016/11/09 2016/11/16 rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo10090 rogid:XDNP6V5SG9TAWLDem6X/Pq+zofY10090 rigid:2ZaqPO8AAsL2eYqHpN5eLqoP6r8 false - sufficient binding region:334-437 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P62827 uniprotkb:Q6ZQE4 intact:EBI-286564|uniprotkb:Q3U954|uniprotkb:Q811M2|uniprotkb:Q86V08|uniprotkb:P17080|uniprotkb:P28746|uniprotkb:P28747|uniprotkb:Q9UDJ5|uniprotkb:Q9CSP3|uniprotkb:Q9CWI7|uniprotkb:Q9CZA2|uniprotkb:Q9UEU9|ensembl:ENSMUSP00000031383|ensembl:ENSMUSP00000106975 intact:EBI-12595939|ensembl:ENSMUSP00000045988 psi-mi:ran_mouse(display_long)|uniprotkb:GTPase Ran(gene name synonym)|uniprotkb:Ras-related nuclear protein(gene name synonym)|uniprotkb:Ras-like protein TC4(gene name synonym)|uniprotkb:Ran(gene name)|psi-mi:Ran(display_short)|uniprotkb:Rasl2-8(gene name synonym) psi-mi:nemp1_mouse(display_long)|uniprotkb:Nemp1(gene name)|psi-mi:Nemp1(display_short)|uniprotkb:Kiaa0286(gene name synonym)|uniprotkb:Tmem194(gene name synonym)|uniprotkb:Tmem194a(gene name synonym) psi-mi:"MI:0096"(pull down) Shibano et al. (2014) pubmed:25946333|imex:IM-25595 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-12595995|imex:IM-25595-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033417.1|refseq:XP_006504343.1|ensembl:ENSMUSG00000029430(gene)|ensembl:ENSMUST00000031383(transcript)|ensembl:ENSMUST00000111343(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0002177"(manchette)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0019003"(GDP binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030496"(midbody)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034629"|go:"GO:0036126"(sperm flagellum)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042470"(melanosome)|go:"GO:0042565"(RNA nuclear export complex)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0046039"(GTP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:0055037"(recycling endosome)|go:"GO:0061015"(snRNA import into nucleus)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:1902570"(protein localization to nucleolus)|interpro:IPR001806(Ras GTPase)|interpro:IPR002041(Ran GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P62827|reactome:R-MMU-1655829|reactome:R-MMU-5578749|reactome:R-MMU-9615933 ensembl:ENSMUSG00000040195(gene)|ensembl:ENSMUST00000048099(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071763"(nuclear membrane organization)|interpro:IPR019358|refseq:NP_001106682.1 - - - figure legend:3C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/11/09 2016/11/09 rogid:trIUv5n3nI5d0rkfDTgw/6ubxMA10090 rogid:XDNP6V5SG9TAWLDem6X/Pq+zofY10090 rigid:giD7AgA+VlUngCIQXRljf8+NO7k false ha tag:c-c|mutation:69-69|mutation decreasing interaction strength:24-24 glutathione s tranferase tag:n-n|sufficient binding region:334-437 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P62827 uniprotkb:Q6ZQE4 intact:EBI-286564|uniprotkb:Q3U954|uniprotkb:Q811M2|uniprotkb:Q86V08|uniprotkb:P17080|uniprotkb:P28746|uniprotkb:P28747|uniprotkb:Q9UDJ5|uniprotkb:Q9CSP3|uniprotkb:Q9CWI7|uniprotkb:Q9CZA2|uniprotkb:Q9UEU9|ensembl:ENSMUSP00000031383|ensembl:ENSMUSP00000106975 intact:EBI-12595939|ensembl:ENSMUSP00000045988 psi-mi:ran_mouse(display_long)|uniprotkb:GTPase Ran(gene name synonym)|uniprotkb:Ras-related nuclear protein(gene name synonym)|uniprotkb:Ras-like protein TC4(gene name synonym)|uniprotkb:Ran(gene name)|psi-mi:Ran(display_short)|uniprotkb:Rasl2-8(gene name synonym) psi-mi:nemp1_mouse(display_long)|uniprotkb:Nemp1(gene name)|psi-mi:Nemp1(display_short)|uniprotkb:Kiaa0286(gene name synonym)|uniprotkb:Tmem194(gene name synonym)|uniprotkb:Tmem194a(gene name synonym) psi-mi:"MI:0096"(pull down) Shibano et al. (2014) pubmed:25946333|imex:IM-25595 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-12596019|imex:IM-25595-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033417.1|refseq:XP_006504343.1|ensembl:ENSMUSG00000029430(gene)|ensembl:ENSMUST00000031383(transcript)|ensembl:ENSMUST00000111343(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0002177"(manchette)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0019003"(GDP binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030496"(midbody)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034629"|go:"GO:0036126"(sperm flagellum)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042470"(melanosome)|go:"GO:0042565"(RNA nuclear export complex)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0046039"(GTP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:0055037"(recycling endosome)|go:"GO:0061015"(snRNA import into nucleus)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:1902570"(protein localization to nucleolus)|interpro:IPR001806(Ras GTPase)|interpro:IPR002041(Ran GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P62827|reactome:R-MMU-1655829|reactome:R-MMU-5578749|reactome:R-MMU-9615933 ensembl:ENSMUSG00000040195(gene)|ensembl:ENSMUST00000048099(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071763"(nuclear membrane organization)|interpro:IPR019358|refseq:NP_001106682.1 - - - figure legend:3D|comment:GTP was present in the buffer.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/11/09 2016/11/16 rogid:trIUv5n3nI5d0rkfDTgw/6ubxMA10090 rogid:XDNP6V5SG9TAWLDem6X/Pq+zofY10090 rigid:giD7AgA+VlUngCIQXRljf8+NO7k false myc tag:n-n|mutation:69-69 glutathione s tranferase tag:n-n|sufficient binding region:334-437 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P62827 uniprotkb:Q6ZQE4 intact:EBI-286564|uniprotkb:Q3U954|uniprotkb:Q811M2|uniprotkb:Q86V08|uniprotkb:P17080|uniprotkb:P28746|uniprotkb:P28747|uniprotkb:Q9UDJ5|uniprotkb:Q9CSP3|uniprotkb:Q9CWI7|uniprotkb:Q9CZA2|uniprotkb:Q9UEU9|ensembl:ENSMUSP00000031383|ensembl:ENSMUSP00000106975 intact:EBI-12595939|ensembl:ENSMUSP00000045988 psi-mi:ran_mouse(display_long)|uniprotkb:GTPase Ran(gene name synonym)|uniprotkb:Ras-related nuclear protein(gene name synonym)|uniprotkb:Ras-like protein TC4(gene name synonym)|uniprotkb:Ran(gene name)|psi-mi:Ran(display_short)|uniprotkb:Rasl2-8(gene name synonym) psi-mi:nemp1_mouse(display_long)|uniprotkb:Nemp1(gene name)|psi-mi:Nemp1(display_short)|uniprotkb:Kiaa0286(gene name synonym)|uniprotkb:Tmem194(gene name synonym)|uniprotkb:Tmem194a(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) Shibano et al. (2014) pubmed:25946333|imex:IM-25595 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-12596125|imex:IM-25595-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033417.1|refseq:XP_006504343.1|ensembl:ENSMUSG00000029430(gene)|ensembl:ENSMUST00000031383(transcript)|ensembl:ENSMUST00000111343(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0002177"(manchette)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0019003"(GDP binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030496"(midbody)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034629"|go:"GO:0036126"(sperm flagellum)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042470"(melanosome)|go:"GO:0042565"(RNA nuclear export complex)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0046039"(GTP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:0055037"(recycling endosome)|go:"GO:0061015"(snRNA import into nucleus)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:1902570"(protein localization to nucleolus)|interpro:IPR001806(Ras GTPase)|interpro:IPR002041(Ran GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P62827|reactome:R-MMU-1655829|reactome:R-MMU-5578749|reactome:R-MMU-9615933 ensembl:ENSMUSG00000040195(gene)|ensembl:ENSMUST00000048099(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071763"(nuclear membrane organization)|interpro:IPR019358|refseq:NP_001106682.1 go:"GO:0005635"(nuclear envelope) - - figure legend:5B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2016/11/09 2016/11/09 rogid:trIUv5n3nI5d0rkfDTgw/6ubxMA10090 rogid:XDNP6V5SG9TAWLDem6X/Pq+zofY10090 rigid:giD7AgA+VlUngCIQXRljf8+NO7k false myc tag:n-n ha tag:c-c - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining)