#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9QXY6 uniprotkb:Q5SUF7 intact:EBI-775304|uniprotkb:Q8K590|ensembl:ENSMUSP00000024860 intact:EBI-11683814|ensembl:ENSMUSP00000103418 psi-mi:ehd3_mouse(display_long)|uniprotkb:Ehd3(gene name)|psi-mi:Ehd3(display_short)|uniprotkb:Ehd2(gene name synonym) psi-mi:q5suf7_mouse(display_long)|uniprotkb:Cacna1g(gene name)|psi-mi:Cacna1g(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Curran et al. (2015) imex:IM-25093|pubmed:25825486 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-11683809|imex:IM-25093-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_065603.2|ensembl:ENSMUSG00000024065(gene)|ensembl:ENSMUST00000024860(transcript)|go:"GO:0001881"(receptor recycling)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0008289"(lipid binding)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0020018"(ciliary pocket membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0032456"(endocytic recycling)|go:"GO:0034498"(early endosome to Golgi transport)|go:"GO:0043209"(myelin sheath)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060271"(cilium assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086036"(regulation of cardiac muscle cell membrane potential)|go:"GO:0090160"(Golgi to lysosome transport)|go:"GO:1901387"(positive regulation of voltage-gated calcium channel activity)|go:"GO:1903358"(regulation of Golgi organization)|go:"GO:1903779"(regulation of cardiac conduction)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR022812|interpro:IPR027417|interpro:IPR029951|interpro:IPR030381|interpro:IPR031692|interpro:IPR040990|mint:Q9QXY6|reactome:R-MMU-983231 refseq:XP_006532133.1|ensembl:ENSMUSG00000020866(gene)|ensembl:ENSMUST00000107789(transcript)|go:"GO:0001508"(action potential)|go:"GO:0001518"(voltage-gated sodium channel complex)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005248"(voltage-gated sodium channel activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008332"(low voltage-gated calcium channel activity)|go:"GO:0010045"(response to nickel cation)|go:"GO:0014824"(artery smooth muscle contraction)|go:"GO:0016020"(membrane)|go:"GO:0019228"(neuronal action potential)|go:"GO:0030425"(dendrite)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044297"(cell body)|go:"GO:0045202"(synapse)|go:"GO:0045956"(positive regulation of calcium ion-dependent exocytosis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:0097110"(scaffold protein binding)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005445(Voltage-dependent calcium channel, T-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR027359 - - - figure legend:5A and B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2016/04/04 2016/04/04 rogid:COp4bL5nQo5RCRHYzQYqtdl4Xjo10090 rogid:BS22GiCTB36LEjDTKB8DbEGy8H010090 rigid:0i239to8N43pzpJ6WML2K+d/KSs false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9QXY6 uniprotkb:O88427 intact:EBI-775304|uniprotkb:Q8K590|ensembl:ENSMUSP00000024860 intact:EBI-11683776|uniprotkb:B2RQQ0|uniprotkb:E9QNT0|uniprotkb:Q80TJ2|uniprotkb:Q9JKU5 psi-mi:ehd3_mouse(display_long)|uniprotkb:Ehd3(gene name)|psi-mi:Ehd3(display_short)|uniprotkb:Ehd2(gene name synonym) psi-mi:cac1h_mouse(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav3.2(gene name synonym)|uniprotkb:Cacna1h(gene name)|psi-mi:Cacna1h(display_short)|uniprotkb:Kiaa1120(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Curran et al. (2015) imex:IM-25093|pubmed:25825486 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-11683809|imex:IM-25093-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_065603.2|ensembl:ENSMUSG00000024065(gene)|ensembl:ENSMUST00000024860(transcript)|go:"GO:0001881"(receptor recycling)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0008289"(lipid binding)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0020018"(ciliary pocket membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0032456"(endocytic recycling)|go:"GO:0034498"(early endosome to Golgi transport)|go:"GO:0043209"(myelin sheath)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060271"(cilium assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086036"(regulation of cardiac muscle cell membrane potential)|go:"GO:0090160"(Golgi to lysosome transport)|go:"GO:1901387"(positive regulation of voltage-gated calcium channel activity)|go:"GO:1903358"(regulation of Golgi organization)|go:"GO:1903779"(regulation of cardiac conduction)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR022812|interpro:IPR027417|interpro:IPR029951|interpro:IPR030381|interpro:IPR031692|interpro:IPR040990|mint:Q9QXY6|reactome:R-MMU-983231 interpro:IPR005821(Ion transport)|interpro:IPR005445(Voltage-dependent calcium channel, T-type, alpha-1 subunit)|go:"GO:0001518"(voltage-gated sodium channel complex)|go:"GO:0005244"(voltage-gated ion channel activity)|go:"GO:0005248"(voltage-gated sodium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0005901"(caveola)|go:"GO:0006816"(calcium ion transport)|go:"GO:0008332"(low voltage-gated calcium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019228"(neuronal action potential)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0030425"(dendrite)|go:"GO:0032342"(aldosterone biosynthetic process)|go:"GO:0034651"(cortisol biosynthetic process)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0045956"(positive regulation of calcium ion-dependent exocytosis)|go:"GO:0046872"(metal ion binding)|go:"GO:0070509"(calcium ion import)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098662"(inorganic cation transmembrane transport)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:0106134"(positive regulation of cardiac muscle cell contraction)|go:"GO:2000344"(positive regulation of acrosome reaction)|interpro:IPR027359 - - - figure legend:5A and B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2016/04/04 2016/04/04 rogid:COp4bL5nQo5RCRHYzQYqtdl4Xjo10090 rogid:8GLlrhs8fYmO+ddcbhxjDpR/omc10090 rigid:0i239to8N43pzpJ6WML2K+d/KSs false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)