#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P19712-PRO_0000038050 uniprotkb:Q764M6 intact:EBI-10901281 intact:EBI-12512266|ensembl:ENSSSCP00040008173 psi-mi:p19712-pro_0000038050(display_long) psi-mi:irf3_pig(display_long)|uniprotkb:IRF3(gene name)|psi-mi:IRF3(display_short) psi-mi:"MI:0018"(two hybrid) Mine et al. (2015) pubmed:25809915|imex:IM-26066 taxid:11097(CSFV)|taxid:11097("Classical swine fever virus (strain Alfort)") taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-12520796|imex:IM-26066-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-10901236(chain-parent) ensembl:ENSSSCG00040014662(gene)|ensembl:ENSSSCT00040019663(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035666"(TRIF-dependent toll-like receptor signaling pathway)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|go:"GO:0098586"(cellular response to virus)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|reactome:R-SSC-1169408|reactome:R-SSC-1606341|reactome:R-SSC-168928|reactome:R-SSC-3134973|reactome:R-SSC-3134975|reactome:R-SSC-3270619|reactome:R-SSC-9013973|reactome:R-SSC-918233|reactome:R-SSC-933541|reactome:R-SSC-936440|reactome:R-SSC-936964|refseq:NP_998935.1 - chain-seq-start:1|chain-seq-end:168 - figure legend:6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/09/16 2016/09/16 rogid:neST34w2UpLSt2CN+sb1qrGppCM11097 rogid:k8mIgjpiImgr8GDDQbkAz1SlbfI9823 rigid:Xsv1Lb12laG6AYocW4kLG//TZHg false dna binding domain tag:?-?|mutation decreasing interaction strength:136-136 vp16 activation domain:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) intact:EBI-12522797 uniprotkb:Q764M6 - intact:EBI-12512266|ensembl:ENSSSCP00040008173 psi-mi:a0a0a8jet1_9flav(display_short)|psi-mi:EBI-12522797(display_long) psi-mi:irf3_pig(display_long)|uniprotkb:IRF3(gene name)|psi-mi:IRF3(display_short) psi-mi:"MI:0018"(two hybrid) Mine et al. (2015) pubmed:25809915|imex:IM-26066 taxid:11097(CSFV)|taxid:11097("Classical swine fever virus (strain Alfort)") taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-12522794|imex:IM-26066-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:A0A0A8JET1 ensembl:ENSSSCG00040014662(gene)|ensembl:ENSSSCT00040019663(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035666"(TRIF-dependent toll-like receptor signaling pathway)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|go:"GO:0098586"(cellular response to virus)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|reactome:R-SSC-1169408|reactome:R-SSC-1606341|reactome:R-SSC-168928|reactome:R-SSC-3134973|reactome:R-SSC-3134975|reactome:R-SSC-3270619|reactome:R-SSC-9013973|reactome:R-SSC-918233|reactome:R-SSC-933541|reactome:R-SSC-936440|reactome:R-SSC-936964|refseq:NP_998935.1 - - - figure legend:6|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/09/16 2016/09/22 rogid:S4zub6NiV2qIL2D++7N8P+ib22Q11097 rogid:k8mIgjpiImgr8GDDQbkAz1SlbfI9823 rigid:ax1qRhx57UPXPoDPx7BMZmRZGsU false mutation increasing interaction strength:40-40|mutation increasing interaction strength:17-17,61-61|sufficient binding region:1..1-168..168|mutation increasing interaction strength:40-40,61-61,17-17 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)