#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P19620 uniprotkb:P19712-PRO_0000038060 intact:EBI-7437630|intact:MINT-1214816|uniprotkb:Q5Y2C7 intact:EBI-12513719 psi-mi:anxa2_pig(display_long)|uniprotkb:ANXA2(gene name)|psi-mi:ANXA2(display_short)|uniprotkb:ANX2(gene name synonym)|uniprotkb:Annexin-2(gene name synonym)|uniprotkb:Annexin II(gene name synonym)|uniprotkb:Lipocortin II(gene name synonym)|uniprotkb:Calpactin I heavy chain(gene name synonym)|uniprotkb:Chromobindin-8(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:Protein I(gene name synonym)|uniprotkb:Placental anticoagulant protein IV(gene name synonym)|uniprotkb:Calpactin-1 heavy chain(gene name synonym) psi-mi:p19712-pro_0000038060(display_long) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Sheng et al. (2015) pubmed:25593157|imex:IM-25919 taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)") taxid:11097(CSFV)|taxid:11097("Classical swine fever virus (strain Alfort)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-12513716|imex:IM-25919-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR018252|interpro:IPR018502|refseq:NP_001005726.1|interpro:IPR001464(Annexin)|interpro:IPR002389(Annexin, type II)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0019834"(phospholipase A2 inhibitor activity)|go:"GO:0031982"(vesicle)|go:"GO:0042470"(melanosome)|go:"GO:0044548"(S100 protein binding)|go:"GO:0044794"(positive regulation by host of viral process)|go:"GO:0046790"(virion binding)|go:"GO:1903902"(positive regulation of viral life cycle)|go:"GO:1990665"(AnxA2-p11 complex)|go:"GO:0002020"(protease binding)|go:"GO:0001786"(phosphatidylserine binding)|interpro:IPR037104 intact:EBI-10901236(chain-parent) - comment:mint|function:Calcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids. It binds two calcium ions with high affinity chain-seq-start:2684|chain-seq-end:3180 figure legend:3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9823(pig-pk15)|taxid:9823(pig pk15) - 2016/08/24 2016/08/25 rogid:/Xt1+3aPx+S0wdCln1IkrP6OAms9823 rogid:Ov/soxO3fbg8JUYR1UKYwOQmFUw11097 rigid:81uYcRUlnuhYwybTOuZEaGnLK6M false - necessary binding region:335-389|mutation disrupting interaction strength:338-338|mutation disrupting interaction strength:359-359|mutation disrupting interaction strength:378-378|mutation decreasing interaction strength:378-378|flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)