#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q16181 uniprotkb:Q8IYM1 intact:EBI-2009373|uniprotkb:Q52M76|uniprotkb:Q6NX50|ensembl:ENSP00000381992 intact:EBI-2585067|uniprotkb:Q96LL0|uniprotkb:Q0P6B0|uniprotkb:Q1PBH0|ensembl:ENSP00000268231 psi-mi:sept7_human(display_long)|uniprotkb:SEPTIN7(gene name)|psi-mi:SEPTIN7(display_short)|uniprotkb:CDC10(gene name synonym)|uniprotkb:CDC10 protein homolog(gene name synonym)|uniprotkb:SEPT7(gene name synonym) psi-mi:sep12_human(display_long)|uniprotkb:SEPTIN12(gene name)|psi-mi:SEPTIN12(display_short)|uniprotkb:SEPT12(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Kuo et al. (2015) pubmed:25588830|imex:IM-25619 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-12598320|imex:IM-25619-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001779.3|dip:DIP-47093N|ensembl:ENSG00000122545(gene)|ensembl:ENST00000399034(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016476"(regulation of embryonic cell shape)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097227"(sperm annulus)|go:"GO:0097730"(non-motile cilium)|go:"GO:1902857"(positive regulation of non-motile cilium assembly)|interpro:IPR008115(Septin 7)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:2QAG|rcsb pdb:3T5D|rcsb pdb:3TW4|rcsb pdb:6N0B|rcsb pdb:6N12|rcsb pdb:6UQQ|reactome:R-HSA-5687128 refseq:NP_001147930.1|refseq:NP_653206.2|refseq:XP_006720909.1|ensembl:ENSG00000140623(gene)|ensembl:ENST00000268231(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097227"(sperm annulus)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:6MQ9|rcsb pdb:6MQB|rcsb pdb:6MQK|rcsb pdb:6MQL omim:614822(see-also)|go:"GO:0097227"(sperm annulus) - - figure legend:1A, 6A ,6E|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-sperm)|taxid:9606(Homo sapiens - sperm) - 2016/11/16 2016/11/16 rogid:CweIjGLXC7eubvKR7vkkihEkcHg9606 rogid:JVg1xMDlUm2RuG5VukrGDWI/Rz09606 rigid:hDfziRCIGAQdBG6Yaq7Pa2Z74Ac false - mutation disrupting interaction:197-197 - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q14141 uniprotkb:Q8IYM1 intact:EBI-745901|uniprotkb:Q5JTK0|uniprotkb:Q969W5|uniprotkb:Q96A13|uniprotkb:Q96GR1|uniprotkb:Q96P86|uniprotkb:Q96P87|intact:EBI-1047521|ensembl:ENSP00000341524 intact:EBI-2585067|uniprotkb:Q96LL0|uniprotkb:Q0P6B0|uniprotkb:Q1PBH0|ensembl:ENSP00000268231 psi-mi:sept6_human(display_long)|uniprotkb:SEPTIN6(gene name)|psi-mi:SEPTIN6(display_short)|uniprotkb:KIAA0128(gene name synonym)|uniprotkb:SEP2(gene name synonym)|uniprotkb:SEPT6(gene name synonym) psi-mi:sep12_human(display_long)|uniprotkb:SEPTIN12(gene name)|psi-mi:SEPTIN12(display_short)|uniprotkb:SEPT12(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Kuo et al. (2015) pubmed:25588830|imex:IM-25619 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-12598325|imex:IM-25619-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000125354(gene)|ensembl:ENST00000343984(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000776"(kinetochore)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005819"(spindle)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032173"(septin collar)|go:"GO:0034613"(cellular protein localization)|go:"GO:0043679"(axon terminus)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097227"(sperm annulus)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|interpro:IPR030644|mint:Q14141|rcsb pdb:2QAG|rcsb pdb:6UPA|rcsb pdb:6WBP|refseq:NP_055944.2|refseq:NP_665798.1|refseq:NP_665799.1|refseq:NP_665801.1|refseq:XP_006724813.1|dip:DIP-38218N refseq:NP_001147930.1|refseq:NP_653206.2|refseq:XP_006720909.1|ensembl:ENSG00000140623(gene)|ensembl:ENST00000268231(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097227"(sperm annulus)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:6MQ9|rcsb pdb:6MQB|rcsb pdb:6MQK|rcsb pdb:6MQL omim:614822(see-also)|go:"GO:0097227"(sperm annulus) - - figure legend:1B, 6B, 6F|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-sperm)|taxid:9606(Homo sapiens - sperm) - 2016/11/16 2016/11/16 rogid:gH1JHXyE/7o3I8i4ZS3bMoF7zvU9606 rogid:JVg1xMDlUm2RuG5VukrGDWI/Rz09606 rigid:fh0B7vzVkq+giBNXe3VL1MJsKUo false - mutation disrupting interaction:197-197 - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q15019 uniprotkb:Q8IYM1 intact:EBI-741220|intact:EBI-28986019|ensembl:ENSP00000353157|ensembl:ENSP00000375832|ensembl:ENSP00000375834|ensembl:ENSP00000385172|uniprotkb:Q14132|uniprotkb:Q8IUK9|uniprotkb:Q96CB0|uniprotkb:B4DGE8|uniprotkb:Q53QU3 intact:EBI-2585067|uniprotkb:Q96LL0|uniprotkb:Q0P6B0|uniprotkb:Q1PBH0|ensembl:ENSP00000268231 psi-mi:sept2_human(display_long)|uniprotkb:SEPTIN2(gene name)|psi-mi:SEPTIN2(display_short)|uniprotkb:DIFF6(gene name synonym)|uniprotkb:KIAA0158(gene name synonym)|uniprotkb:NEDD5(gene name synonym)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 5(gene name synonym)|uniprotkb:SEPT2(gene name synonym) psi-mi:sep12_human(display_long)|uniprotkb:SEPTIN12(gene name)|psi-mi:SEPTIN12(display_short)|uniprotkb:SEPT12(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Kuo et al. (2015) pubmed:25588830|imex:IM-25619 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-12598330|imex:IM-25619-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001269901.1|refseq:NP_001269902.1|ensembl:ENSG00000168385(gene)|ensembl:ENST00000360051(transcript)|ensembl:ENST00000391971(transcript)|ensembl:ENST00000391973(transcript)|ensembl:ENST00000402092(transcript)|go:"GO:0000145"(exocyst)|go:"GO:0000776"(kinetochore)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005886"(plasma membrane)|go:"GO:0005930"(axoneme)|go:"GO:0005940"(septin ring)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042802"(identical protein binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045296"(cadherin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097227"(sperm annulus)|go:"GO:0097730"(non-motile cilium)|interpro:IPR008113(Septin 2)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|mint:Q15019|rcsb pdb:2QA5|rcsb pdb:2QAG|rcsb pdb:2QNR|rcsb pdb:6UPA|rcsb pdb:6UPQ|rcsb pdb:6UPR|reactome:R-HSA-5620912|refseq:NP_001008491.1|refseq:NP_001008492.1|refseq:NP_004395.1|refseq:NP_006146.1|refseq:XP_016859694.1|refseq:XP_016859695.1|refseq:NP_001307958.1|refseq:NP_001307959.1|refseq:NP_001307960.1|refseq:NP_001307961.1|refseq:NP_001307962.1|refseq:NP_001307963.1|refseq:NP_001307964.1|ensembl:ENSP00000353157|ensembl:ENSP00000375832|ensembl:ENSP00000375834|ensembl:ENST00000401990|ensembl:ENSP00000385109|ensembl:ENSP00000385172|ensembl:ENST00000616972|ensembl:ENSP00000479861|dip:DIP-38220N refseq:NP_001147930.1|refseq:NP_653206.2|refseq:XP_006720909.1|ensembl:ENSG00000140623(gene)|ensembl:ENST00000268231(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097227"(sperm annulus)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:6MQ9|rcsb pdb:6MQB|rcsb pdb:6MQK|rcsb pdb:6MQL omim:614822(see-also)|go:"GO:0097227"(sperm annulus) crc64:12CCBBE30806F92F - figure legend:1C, 6C, 6G|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-sperm)|taxid:9606(Homo sapiens - sperm) - 2016/11/16 2016/11/16 rogid:H0Us8GtPe2XuXlOYXC0DX79kB/49606 rogid:JVg1xMDlUm2RuG5VukrGDWI/Rz09606 rigid:A4bByG4ap2elejkOD6pQ47/pty4 false - mutation disrupting interaction:197-197 - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:O43236 uniprotkb:Q8IYM1 intact:EBI-1047513|uniprotkb:Q9UM58|uniprotkb:Q6IAP3|uniprotkb:B2RD42|uniprotkb:B3KSX9|uniprotkb:B4DXC6|uniprotkb:B4DXV5|uniprotkb:Q9H315|ensembl:ENSP00000321674|uniprotkb:A0A5F9ZHH3|uniprotkb:Q8N821|uniprotkb:Q8NEP4|intact:EBI-25939820|intact:EBI-13336111 intact:EBI-2585067|uniprotkb:Q96LL0|uniprotkb:Q0P6B0|uniprotkb:Q1PBH0|ensembl:ENSP00000268231 psi-mi:sept4_human(display_long)|uniprotkb:SEPTIN4(gene name)|psi-mi:SEPTIN4(display_short)|uniprotkb:ARTS(gene name synonym)|uniprotkb:Apoptosis-related protein in the TGF-beta signaling pathway(gene name synonym)|uniprotkb:Bradeion beta(gene name synonym)|uniprotkb:Brain protein H5(gene name synonym)|uniprotkb:CE5B3 beta(gene name synonym)|uniprotkb:Cell division control-related protein 2(gene name synonym)|uniprotkb:Cerebral protein 7(gene name synonym)|uniprotkb:PNUTL2(gene name synonym)|uniprotkb:Peanut-like protein 2(gene name synonym)|uniprotkb:SEP4(gene name synonym)|uniprotkb:SEPT4(gene name synonym)|uniprotkb:hucep-7(orf name)|uniprotkb:C17orf47(gene name synonym) psi-mi:sep12_human(display_long)|uniprotkb:SEPTIN12(gene name)|psi-mi:SEPTIN12(display_short)|uniprotkb:SEPT12(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Kuo et al. (2015) pubmed:25588830|imex:IM-25619 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-12598335|imex:IM-25619-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011523213.1|refseq:XP_011523214.1|refseq:NP_001185642.1|refseq:NP_004565.1|refseq:NP_536341.1|refseq:NP_536340.1|refseq:NP_001033793.2|refseq:NP_001243711.1|refseq:NP_001243751.1|ensembl:ENSG00000108387(gene)|interpro:IPR027417|interpro:IPR030379|mint:O43236|rcsb pdb:6WB3|reactome:R-HSA-111457|reactome:R-HSA-111469|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|ensembl:ENST00000317268(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005940"(septin ring)|go:"GO:0006915"(apoptotic process)|go:"GO:0001764"(neuron migration)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0003924"(GTPase activity)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0005198"(structural molecule activity)|go:"GO:0031105"(septin complex)|go:"GO:0005525"(GTP binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0032153"(cell division site)|go:"GO:0034613"(cellular protein localization)|go:"GO:0005654"(nucleoplasm)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043204"(perikaryon)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097227"(sperm annulus)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR016491(Septin)|refseq:XP_006722017.1|refseq:XP_006722018.1 refseq:NP_001147930.1|refseq:NP_653206.2|refseq:XP_006720909.1|ensembl:ENSG00000140623(gene)|ensembl:ENST00000268231(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097227"(sperm annulus)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:6MQ9|rcsb pdb:6MQB|rcsb pdb:6MQK|rcsb pdb:6MQL omim:614822(see-also)|go:"GO:0097227"(sperm annulus) - - figure legend:1D, 6D, 6H|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-sperm)|taxid:9606(Homo sapiens - sperm) - 2016/11/16 2016/11/16 rogid:bS5LZDK5bxr0WEZsE35enupzNQs9606 rogid:JVg1xMDlUm2RuG5VukrGDWI/Rz09606 rigid:F+EctJgGKKvMATjbk1mNPCJjFzg false - mutation disrupting interaction:197-197 - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q15019 uniprotkb:Q8IYM1 intact:EBI-741220|intact:EBI-28986019|ensembl:ENSP00000353157|ensembl:ENSP00000375832|ensembl:ENSP00000375834|ensembl:ENSP00000385172|uniprotkb:Q14132|uniprotkb:Q8IUK9|uniprotkb:Q96CB0|uniprotkb:B4DGE8|uniprotkb:Q53QU3 intact:EBI-2585067|uniprotkb:Q96LL0|uniprotkb:Q0P6B0|uniprotkb:Q1PBH0|ensembl:ENSP00000268231 psi-mi:sept2_human(display_long)|uniprotkb:SEPTIN2(gene name)|psi-mi:SEPTIN2(display_short)|uniprotkb:DIFF6(gene name synonym)|uniprotkb:KIAA0158(gene name synonym)|uniprotkb:NEDD5(gene name synonym)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 5(gene name synonym)|uniprotkb:SEPT2(gene name synonym) psi-mi:sep12_human(display_long)|uniprotkb:SEPTIN12(gene name)|psi-mi:SEPTIN12(display_short)|uniprotkb:SEPT12(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2015) pubmed:25588830|imex:IM-25619 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-12598351|imex:IM-25619-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001269901.1|refseq:NP_001269902.1|ensembl:ENSG00000168385(gene)|ensembl:ENST00000360051(transcript)|ensembl:ENST00000391971(transcript)|ensembl:ENST00000391973(transcript)|ensembl:ENST00000402092(transcript)|go:"GO:0000145"(exocyst)|go:"GO:0000776"(kinetochore)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005886"(plasma membrane)|go:"GO:0005930"(axoneme)|go:"GO:0005940"(septin ring)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042802"(identical protein binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045296"(cadherin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097227"(sperm annulus)|go:"GO:0097730"(non-motile cilium)|interpro:IPR008113(Septin 2)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|mint:Q15019|rcsb pdb:2QA5|rcsb pdb:2QAG|rcsb pdb:2QNR|rcsb pdb:6UPA|rcsb pdb:6UPQ|rcsb pdb:6UPR|reactome:R-HSA-5620912|refseq:NP_001008491.1|refseq:NP_001008492.1|refseq:NP_004395.1|refseq:NP_006146.1|refseq:XP_016859694.1|refseq:XP_016859695.1|refseq:NP_001307958.1|refseq:NP_001307959.1|refseq:NP_001307960.1|refseq:NP_001307961.1|refseq:NP_001307962.1|refseq:NP_001307963.1|refseq:NP_001307964.1|ensembl:ENSP00000353157|ensembl:ENSP00000375832|ensembl:ENSP00000375834|ensembl:ENST00000401990|ensembl:ENSP00000385109|ensembl:ENSP00000385172|ensembl:ENST00000616972|ensembl:ENSP00000479861|dip:DIP-38220N refseq:NP_001147930.1|refseq:NP_653206.2|refseq:XP_006720909.1|ensembl:ENSG00000140623(gene)|ensembl:ENST00000268231(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097227"(sperm annulus)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:6MQ9|rcsb pdb:6MQB|rcsb pdb:6MQK|rcsb pdb:6MQL - crc64:12CCBBE30806F92F - figure legend:2B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-nt2d1)|taxid:9606("human NTERA-2 d.D1 (NT2D1) testicular embryonal carcinoma cell line") - 2016/11/16 2016/11/16 rogid:H0Us8GtPe2XuXlOYXC0DX79kB/49606 rogid:JVg1xMDlUm2RuG5VukrGDWI/Rz09606 rigid:A4bByG4ap2elejkOD6pQ47/pty4 false ha tag:?-? green fluorescent protein tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q14141 uniprotkb:Q8IYM1 intact:EBI-745901|uniprotkb:Q5JTK0|uniprotkb:Q969W5|uniprotkb:Q96A13|uniprotkb:Q96GR1|uniprotkb:Q96P86|uniprotkb:Q96P87|intact:EBI-1047521|ensembl:ENSP00000341524 intact:EBI-2585067|uniprotkb:Q96LL0|uniprotkb:Q0P6B0|uniprotkb:Q1PBH0|ensembl:ENSP00000268231 psi-mi:sept6_human(display_long)|uniprotkb:SEPTIN6(gene name)|psi-mi:SEPTIN6(display_short)|uniprotkb:KIAA0128(gene name synonym)|uniprotkb:SEP2(gene name synonym)|uniprotkb:SEPT6(gene name synonym) psi-mi:sep12_human(display_long)|uniprotkb:SEPTIN12(gene name)|psi-mi:SEPTIN12(display_short)|uniprotkb:SEPT12(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2015) pubmed:25588830|imex:IM-25619 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-12598356|imex:IM-25619-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000125354(gene)|ensembl:ENST00000343984(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000776"(kinetochore)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005819"(spindle)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032173"(septin collar)|go:"GO:0034613"(cellular protein localization)|go:"GO:0043679"(axon terminus)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097227"(sperm annulus)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|interpro:IPR030644|mint:Q14141|rcsb pdb:2QAG|rcsb pdb:6UPA|rcsb pdb:6WBP|refseq:NP_055944.2|refseq:NP_665798.1|refseq:NP_665799.1|refseq:NP_665801.1|refseq:XP_006724813.1|dip:DIP-38218N refseq:NP_001147930.1|refseq:NP_653206.2|refseq:XP_006720909.1|ensembl:ENSG00000140623(gene)|ensembl:ENST00000268231(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097227"(sperm annulus)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:6MQ9|rcsb pdb:6MQB|rcsb pdb:6MQK|rcsb pdb:6MQL - - - figure legend:2A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-nt2d1)|taxid:9606("human NTERA-2 d.D1 (NT2D1) testicular embryonal carcinoma cell line") - 2016/11/16 2016/11/16 rogid:gH1JHXyE/7o3I8i4ZS3bMoF7zvU9606 rogid:JVg1xMDlUm2RuG5VukrGDWI/Rz09606 rigid:fh0B7vzVkq+giBNXe3VL1MJsKUo false myc tag:c-c flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q16181 uniprotkb:Q8IYM1 intact:EBI-2009373|uniprotkb:Q52M76|uniprotkb:Q6NX50|ensembl:ENSP00000381992 intact:EBI-2585067|uniprotkb:Q96LL0|uniprotkb:Q0P6B0|uniprotkb:Q1PBH0|ensembl:ENSP00000268231 psi-mi:sept7_human(display_long)|uniprotkb:SEPTIN7(gene name)|psi-mi:SEPTIN7(display_short)|uniprotkb:CDC10(gene name synonym)|uniprotkb:CDC10 protein homolog(gene name synonym)|uniprotkb:SEPT7(gene name synonym) psi-mi:sep12_human(display_long)|uniprotkb:SEPTIN12(gene name)|psi-mi:SEPTIN12(display_short)|uniprotkb:SEPT12(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2015) pubmed:25588830|imex:IM-25619 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-12598346|imex:IM-25619-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001779.3|dip:DIP-47093N|ensembl:ENSG00000122545(gene)|ensembl:ENST00000399034(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016476"(regulation of embryonic cell shape)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097227"(sperm annulus)|go:"GO:0097730"(non-motile cilium)|go:"GO:1902857"(positive regulation of non-motile cilium assembly)|interpro:IPR008115(Septin 7)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:2QAG|rcsb pdb:3T5D|rcsb pdb:3TW4|rcsb pdb:6N0B|rcsb pdb:6N12|rcsb pdb:6UQQ|reactome:R-HSA-5687128 refseq:NP_001147930.1|refseq:NP_653206.2|refseq:XP_006720909.1|ensembl:ENSG00000140623(gene)|ensembl:ENST00000268231(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097227"(sperm annulus)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:6MQ9|rcsb pdb:6MQB|rcsb pdb:6MQK|rcsb pdb:6MQL - - - figure legend:2A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-nt2d1)|taxid:9606("human NTERA-2 d.D1 (NT2D1) testicular embryonal carcinoma cell line") - 2016/11/16 2016/11/16 rogid:CweIjGLXC7eubvKR7vkkihEkcHg9606 rogid:JVg1xMDlUm2RuG5VukrGDWI/Rz09606 rigid:hDfziRCIGAQdBG6Yaq7Pa2Z74Ac false flag tag:n-n green fluorescent protein tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:O43236 uniprotkb:Q8IYM1 intact:EBI-1047513|uniprotkb:Q9UM58|uniprotkb:Q6IAP3|uniprotkb:B2RD42|uniprotkb:B3KSX9|uniprotkb:B4DXC6|uniprotkb:B4DXV5|uniprotkb:Q9H315|ensembl:ENSP00000321674|uniprotkb:A0A5F9ZHH3|uniprotkb:Q8N821|uniprotkb:Q8NEP4|intact:EBI-25939820|intact:EBI-13336111 intact:EBI-2585067|uniprotkb:Q96LL0|uniprotkb:Q0P6B0|uniprotkb:Q1PBH0|ensembl:ENSP00000268231 psi-mi:sept4_human(display_long)|uniprotkb:SEPTIN4(gene name)|psi-mi:SEPTIN4(display_short)|uniprotkb:ARTS(gene name synonym)|uniprotkb:Apoptosis-related protein in the TGF-beta signaling pathway(gene name synonym)|uniprotkb:Bradeion beta(gene name synonym)|uniprotkb:Brain protein H5(gene name synonym)|uniprotkb:CE5B3 beta(gene name synonym)|uniprotkb:Cell division control-related protein 2(gene name synonym)|uniprotkb:Cerebral protein 7(gene name synonym)|uniprotkb:PNUTL2(gene name synonym)|uniprotkb:Peanut-like protein 2(gene name synonym)|uniprotkb:SEP4(gene name synonym)|uniprotkb:SEPT4(gene name synonym)|uniprotkb:hucep-7(orf name)|uniprotkb:C17orf47(gene name synonym) psi-mi:sep12_human(display_long)|uniprotkb:SEPTIN12(gene name)|psi-mi:SEPTIN12(display_short)|uniprotkb:SEPT12(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2015) pubmed:25588830|imex:IM-25619 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-12598361|imex:IM-25619-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011523213.1|refseq:XP_011523214.1|refseq:NP_001185642.1|refseq:NP_004565.1|refseq:NP_536341.1|refseq:NP_536340.1|refseq:NP_001033793.2|refseq:NP_001243711.1|refseq:NP_001243751.1|ensembl:ENSG00000108387(gene)|interpro:IPR027417|interpro:IPR030379|mint:O43236|rcsb pdb:6WB3|reactome:R-HSA-111457|reactome:R-HSA-111469|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|ensembl:ENST00000317268(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005940"(septin ring)|go:"GO:0006915"(apoptotic process)|go:"GO:0001764"(neuron migration)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0003924"(GTPase activity)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0005198"(structural molecule activity)|go:"GO:0031105"(septin complex)|go:"GO:0005525"(GTP binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0032153"(cell division site)|go:"GO:0034613"(cellular protein localization)|go:"GO:0005654"(nucleoplasm)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043204"(perikaryon)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097227"(sperm annulus)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR016491(Septin)|refseq:XP_006722017.1|refseq:XP_006722018.1 refseq:NP_001147930.1|refseq:NP_653206.2|refseq:XP_006720909.1|ensembl:ENSG00000140623(gene)|ensembl:ENST00000268231(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097227"(sperm annulus)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:6MQ9|rcsb pdb:6MQB|rcsb pdb:6MQK|rcsb pdb:6MQL - - - figure legend:2A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-nt2d1)|taxid:9606("human NTERA-2 d.D1 (NT2D1) testicular embryonal carcinoma cell line") - 2016/11/16 2016/11/16 rogid:bS5LZDK5bxr0WEZsE35enupzNQs9606 rogid:JVg1xMDlUm2RuG5VukrGDWI/Rz09606 rigid:F+EctJgGKKvMATjbk1mNPCJjFzg false myc tag:c-c flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q16181 uniprotkb:Q8IYM1 intact:EBI-2009373|uniprotkb:Q52M76|uniprotkb:Q6NX50|ensembl:ENSP00000381992 intact:EBI-2585067|uniprotkb:Q96LL0|uniprotkb:Q0P6B0|uniprotkb:Q1PBH0|ensembl:ENSP00000268231 psi-mi:sept7_human(display_long)|uniprotkb:SEPTIN7(gene name)|psi-mi:SEPTIN7(display_short)|uniprotkb:CDC10(gene name synonym)|uniprotkb:CDC10 protein homolog(gene name synonym)|uniprotkb:SEPT7(gene name synonym) psi-mi:sep12_human(display_long)|uniprotkb:SEPTIN12(gene name)|psi-mi:SEPTIN12(display_short)|uniprotkb:SEPT12(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2015) pubmed:25588830|imex:IM-25619 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-12598371|imex:IM-25619-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001779.3|dip:DIP-47093N|ensembl:ENSG00000122545(gene)|ensembl:ENST00000399034(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016476"(regulation of embryonic cell shape)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097227"(sperm annulus)|go:"GO:0097730"(non-motile cilium)|go:"GO:1902857"(positive regulation of non-motile cilium assembly)|interpro:IPR008115(Septin 7)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:2QAG|rcsb pdb:3T5D|rcsb pdb:3TW4|rcsb pdb:6N0B|rcsb pdb:6N12|rcsb pdb:6UQQ|reactome:R-HSA-5687128 refseq:NP_001147930.1|refseq:NP_653206.2|refseq:XP_006720909.1|ensembl:ENSG00000140623(gene)|ensembl:ENST00000268231(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097227"(sperm annulus)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:6MQ9|rcsb pdb:6MQB|rcsb pdb:6MQK|rcsb pdb:6MQL - - - figure legend:2B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-nt2d1)|taxid:9606("human NTERA-2 d.D1 (NT2D1) testicular embryonal carcinoma cell line") - 2016/11/16 2016/11/16 rogid:CweIjGLXC7eubvKR7vkkihEkcHg9606 rogid:JVg1xMDlUm2RuG5VukrGDWI/Rz09606 rigid:hDfziRCIGAQdBG6Yaq7Pa2Z74Ac false flag tag:n-n green fluorescent protein tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q14141 uniprotkb:Q8IYM1 intact:EBI-745901|uniprotkb:Q5JTK0|uniprotkb:Q969W5|uniprotkb:Q96A13|uniprotkb:Q96GR1|uniprotkb:Q96P86|uniprotkb:Q96P87|intact:EBI-1047521|ensembl:ENSP00000341524 intact:EBI-2585067|uniprotkb:Q96LL0|uniprotkb:Q0P6B0|uniprotkb:Q1PBH0|ensembl:ENSP00000268231 psi-mi:sept6_human(display_long)|uniprotkb:SEPTIN6(gene name)|psi-mi:SEPTIN6(display_short)|uniprotkb:KIAA0128(gene name synonym)|uniprotkb:SEP2(gene name synonym)|uniprotkb:SEPT6(gene name synonym) psi-mi:sep12_human(display_long)|uniprotkb:SEPTIN12(gene name)|psi-mi:SEPTIN12(display_short)|uniprotkb:SEPT12(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2015) pubmed:25588830|imex:IM-25619 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-12598384|imex:IM-25619-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000125354(gene)|ensembl:ENST00000343984(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000776"(kinetochore)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005819"(spindle)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032173"(septin collar)|go:"GO:0034613"(cellular protein localization)|go:"GO:0043679"(axon terminus)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097227"(sperm annulus)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|interpro:IPR030644|mint:Q14141|rcsb pdb:2QAG|rcsb pdb:6UPA|rcsb pdb:6WBP|refseq:NP_055944.2|refseq:NP_665798.1|refseq:NP_665799.1|refseq:NP_665801.1|refseq:XP_006724813.1|dip:DIP-38218N refseq:NP_001147930.1|refseq:NP_653206.2|refseq:XP_006720909.1|ensembl:ENSG00000140623(gene)|ensembl:ENST00000268231(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097227"(sperm annulus)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:6MQ9|rcsb pdb:6MQB|rcsb pdb:6MQK|rcsb pdb:6MQL - - - figure legend:2B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-nt2d1)|taxid:9606("human NTERA-2 d.D1 (NT2D1) testicular embryonal carcinoma cell line") - 2016/11/16 2016/11/16 rogid:gH1JHXyE/7o3I8i4ZS3bMoF7zvU9606 rogid:JVg1xMDlUm2RuG5VukrGDWI/Rz09606 rigid:fh0B7vzVkq+giBNXe3VL1MJsKUo false myc tag:c-c flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:O43236 uniprotkb:Q8IYM1 intact:EBI-1047513|uniprotkb:Q9UM58|uniprotkb:Q6IAP3|uniprotkb:B2RD42|uniprotkb:B3KSX9|uniprotkb:B4DXC6|uniprotkb:B4DXV5|uniprotkb:Q9H315|ensembl:ENSP00000321674|uniprotkb:A0A5F9ZHH3|uniprotkb:Q8N821|uniprotkb:Q8NEP4|intact:EBI-25939820|intact:EBI-13336111 intact:EBI-2585067|uniprotkb:Q96LL0|uniprotkb:Q0P6B0|uniprotkb:Q1PBH0|ensembl:ENSP00000268231 psi-mi:sept4_human(display_long)|uniprotkb:SEPTIN4(gene name)|psi-mi:SEPTIN4(display_short)|uniprotkb:ARTS(gene name synonym)|uniprotkb:Apoptosis-related protein in the TGF-beta signaling pathway(gene name synonym)|uniprotkb:Bradeion beta(gene name synonym)|uniprotkb:Brain protein H5(gene name synonym)|uniprotkb:CE5B3 beta(gene name synonym)|uniprotkb:Cell division control-related protein 2(gene name synonym)|uniprotkb:Cerebral protein 7(gene name synonym)|uniprotkb:PNUTL2(gene name synonym)|uniprotkb:Peanut-like protein 2(gene name synonym)|uniprotkb:SEP4(gene name synonym)|uniprotkb:SEPT4(gene name synonym)|uniprotkb:hucep-7(orf name)|uniprotkb:C17orf47(gene name synonym) psi-mi:sep12_human(display_long)|uniprotkb:SEPTIN12(gene name)|psi-mi:SEPTIN12(display_short)|uniprotkb:SEPT12(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2015) pubmed:25588830|imex:IM-25619 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-12598407|imex:IM-25619-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011523213.1|refseq:XP_011523214.1|refseq:NP_001185642.1|refseq:NP_004565.1|refseq:NP_536341.1|refseq:NP_536340.1|refseq:NP_001033793.2|refseq:NP_001243711.1|refseq:NP_001243751.1|ensembl:ENSG00000108387(gene)|interpro:IPR027417|interpro:IPR030379|mint:O43236|rcsb pdb:6WB3|reactome:R-HSA-111457|reactome:R-HSA-111469|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|ensembl:ENST00000317268(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005940"(septin ring)|go:"GO:0006915"(apoptotic process)|go:"GO:0001764"(neuron migration)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0003924"(GTPase activity)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0005198"(structural molecule activity)|go:"GO:0031105"(septin complex)|go:"GO:0005525"(GTP binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0032153"(cell division site)|go:"GO:0034613"(cellular protein localization)|go:"GO:0005654"(nucleoplasm)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043204"(perikaryon)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097227"(sperm annulus)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR016491(Septin)|refseq:XP_006722017.1|refseq:XP_006722018.1 refseq:NP_001147930.1|refseq:NP_653206.2|refseq:XP_006720909.1|ensembl:ENSG00000140623(gene)|ensembl:ENST00000268231(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097227"(sperm annulus)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:6MQ9|rcsb pdb:6MQB|rcsb pdb:6MQK|rcsb pdb:6MQL - - - figure legend:2B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-nt2d1)|taxid:9606("human NTERA-2 d.D1 (NT2D1) testicular embryonal carcinoma cell line") - 2016/11/16 2016/11/16 rogid:bS5LZDK5bxr0WEZsE35enupzNQs9606 rogid:JVg1xMDlUm2RuG5VukrGDWI/Rz09606 rigid:F+EctJgGKKvMATjbk1mNPCJjFzg false myc tag:c-c flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q16181 uniprotkb:Q8IYM1 intact:EBI-2009373|uniprotkb:Q52M76|uniprotkb:Q6NX50|ensembl:ENSP00000381992 intact:EBI-2585067|uniprotkb:Q96LL0|uniprotkb:Q0P6B0|uniprotkb:Q1PBH0|ensembl:ENSP00000268231 psi-mi:sept7_human(display_long)|uniprotkb:SEPTIN7(gene name)|psi-mi:SEPTIN7(display_short)|uniprotkb:CDC10(gene name synonym)|uniprotkb:CDC10 protein homolog(gene name synonym)|uniprotkb:SEPT7(gene name synonym) psi-mi:sep12_human(display_long)|uniprotkb:SEPTIN12(gene name)|psi-mi:SEPTIN12(display_short)|uniprotkb:SEPT12(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2015) pubmed:25588830|imex:IM-25619 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-12598622|imex:IM-25619-18 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001779.3|dip:DIP-47093N|ensembl:ENSG00000122545(gene)|ensembl:ENST00000399034(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016476"(regulation of embryonic cell shape)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097227"(sperm annulus)|go:"GO:0097730"(non-motile cilium)|go:"GO:1902857"(positive regulation of non-motile cilium assembly)|interpro:IPR008115(Septin 7)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:2QAG|rcsb pdb:3T5D|rcsb pdb:3TW4|rcsb pdb:6N0B|rcsb pdb:6N12|rcsb pdb:6UQQ|reactome:R-HSA-5687128 refseq:NP_001147930.1|refseq:NP_653206.2|refseq:XP_006720909.1|ensembl:ENSG00000140623(gene)|ensembl:ENST00000268231(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097227"(sperm annulus)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:6MQ9|rcsb pdb:6MQB|rcsb pdb:6MQK|rcsb pdb:6MQL - - - figure legend:4A|caution:"Sept7 GTP-binding domain (GBD) is stated to be aas 28-298 in Methods section; however Supp fig 2 gives the GBD as aas 47-317. (UniProt gives the GBD as aas 47-318)."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-nt2d1)|taxid:9606("human NTERA-2 d.D1 (NT2D1) testicular embryonal carcinoma cell line") - 2016/11/16 2016/11/17 rogid:CweIjGLXC7eubvKR7vkkihEkcHg9606 rogid:JVg1xMDlUm2RuG5VukrGDWI/Rz09606 rigid:hDfziRCIGAQdBG6Yaq7Pa2Z74Ac false green fluorescent protein tag:n-n|sufficient binding region:28..47-298..317(IPR030379) flag tag:n-n|sufficient binding region:46-319(IPR030379) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q16181 uniprotkb:Q8IYM1 intact:EBI-2009373|uniprotkb:Q52M76|uniprotkb:Q6NX50|ensembl:ENSP00000381992 intact:EBI-2585067|uniprotkb:Q96LL0|uniprotkb:Q0P6B0|uniprotkb:Q1PBH0|ensembl:ENSP00000268231 psi-mi:sept7_human(display_long)|uniprotkb:SEPTIN7(gene name)|psi-mi:SEPTIN7(display_short)|uniprotkb:CDC10(gene name synonym)|uniprotkb:CDC10 protein homolog(gene name synonym)|uniprotkb:SEPT7(gene name synonym) psi-mi:sep12_human(display_long)|uniprotkb:SEPTIN12(gene name)|psi-mi:SEPTIN12(display_short)|uniprotkb:SEPT12(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2015) pubmed:25588830|imex:IM-25619 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-12598634|imex:IM-25619-19 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001779.3|dip:DIP-47093N|ensembl:ENSG00000122545(gene)|ensembl:ENST00000399034(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016476"(regulation of embryonic cell shape)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097227"(sperm annulus)|go:"GO:0097730"(non-motile cilium)|go:"GO:1902857"(positive regulation of non-motile cilium assembly)|interpro:IPR008115(Septin 7)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:2QAG|rcsb pdb:3T5D|rcsb pdb:3TW4|rcsb pdb:6N0B|rcsb pdb:6N12|rcsb pdb:6UQQ|reactome:R-HSA-5687128 refseq:NP_001147930.1|refseq:NP_653206.2|refseq:XP_006720909.1|ensembl:ENSG00000140623(gene)|ensembl:ENST00000268231(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097227"(sperm annulus)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:6MQ9|rcsb pdb:6MQB|rcsb pdb:6MQK|rcsb pdb:6MQL - - - figure legend:4A|caution:"Sept7 GTP-binding domain (GBD) is stated to be aas 28-298 in Methods section; however Supp fig 2 gives the GBD as aas 47-317. (UniProt gives the GBD as aas 47-318)."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-nt2d1)|taxid:9606("human NTERA-2 d.D1 (NT2D1) testicular embryonal carcinoma cell line") - 2016/11/16 2016/11/17 rogid:CweIjGLXC7eubvKR7vkkihEkcHg9606 rogid:JVg1xMDlUm2RuG5VukrGDWI/Rz09606 rigid:hDfziRCIGAQdBG6Yaq7Pa2Z74Ac false green fluorescent protein tag:n-n|sufficient binding region:28..47-298..317(IPR030379) flag tag:n-n|sufficient binding region:46-319(IPR030379) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q16181 uniprotkb:Q8IYM1 intact:EBI-2009373|uniprotkb:Q52M76|uniprotkb:Q6NX50|ensembl:ENSP00000381992 intact:EBI-2585067|uniprotkb:Q96LL0|uniprotkb:Q0P6B0|uniprotkb:Q1PBH0|ensembl:ENSP00000268231 psi-mi:sept7_human(display_long)|uniprotkb:SEPTIN7(gene name)|psi-mi:SEPTIN7(display_short)|uniprotkb:CDC10(gene name synonym)|uniprotkb:CDC10 protein homolog(gene name synonym)|uniprotkb:SEPT7(gene name synonym) psi-mi:sep12_human(display_long)|uniprotkb:SEPTIN12(gene name)|psi-mi:SEPTIN12(display_short)|uniprotkb:SEPT12(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2015) pubmed:25588830|imex:IM-25619 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-12598646|omim:614822|imex:IM-25619-20 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001779.3|dip:DIP-47093N|ensembl:ENSG00000122545(gene)|ensembl:ENST00000399034(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016476"(regulation of embryonic cell shape)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097227"(sperm annulus)|go:"GO:0097730"(non-motile cilium)|go:"GO:1902857"(positive regulation of non-motile cilium assembly)|interpro:IPR008115(Septin 7)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:2QAG|rcsb pdb:3T5D|rcsb pdb:3TW4|rcsb pdb:6N0B|rcsb pdb:6N12|rcsb pdb:6UQQ|reactome:R-HSA-5687128 refseq:NP_001147930.1|refseq:NP_653206.2|refseq:XP_006720909.1|ensembl:ENSG00000140623(gene)|ensembl:ENST00000268231(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097227"(sperm annulus)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:6MQ9|rcsb pdb:6MQB|rcsb pdb:6MQK|rcsb pdb:6MQL - - - figure legend:4D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-nt2d1)|taxid:9606("human NTERA-2 d.D1 (NT2D1) testicular embryonal carcinoma cell line") - 2016/11/16 2016/11/17 rogid:CweIjGLXC7eubvKR7vkkihEkcHg9606 rogid:JVg1xMDlUm2RuG5VukrGDWI/Rz09606 rigid:hDfziRCIGAQdBG6Yaq7Pa2Z74Ac false flag tag:n-n green fluorescent protein tag:c-c|mutation disrupting interaction strength:89-89|mutation disrupting interaction strength:197-197 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8IYM1 uniprotkb:Q8IYM1 intact:EBI-2585067|uniprotkb:Q96LL0|uniprotkb:Q0P6B0|uniprotkb:Q1PBH0|ensembl:ENSP00000268231 intact:EBI-2585067|uniprotkb:Q96LL0|uniprotkb:Q0P6B0|uniprotkb:Q1PBH0|ensembl:ENSP00000268231 psi-mi:sep12_human(display_long)|uniprotkb:SEPTIN12(gene name)|psi-mi:SEPTIN12(display_short)|uniprotkb:SEPT12(gene name synonym) psi-mi:sep12_human(display_long)|uniprotkb:SEPTIN12(gene name)|psi-mi:SEPTIN12(display_short)|uniprotkb:SEPT12(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2015) pubmed:25588830|imex:IM-25619 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-12598693|imex:IM-25619-23 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001147930.1|refseq:NP_653206.2|refseq:XP_006720909.1|ensembl:ENSG00000140623(gene)|ensembl:ENST00000268231(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097227"(sperm annulus)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:6MQ9|rcsb pdb:6MQB|rcsb pdb:6MQK|rcsb pdb:6MQL refseq:NP_001147930.1|refseq:NP_653206.2|refseq:XP_006720909.1|ensembl:ENSG00000140623(gene)|ensembl:ENST00000268231(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097227"(sperm annulus)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:6MQ9|rcsb pdb:6MQB|rcsb pdb:6MQK|rcsb pdb:6MQL - - - figure legend:5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-nt2d1)|taxid:9606("human NTERA-2 d.D1 (NT2D1) testicular embryonal carcinoma cell line") - 2016/11/16 2016/11/17 rogid:JVg1xMDlUm2RuG5VukrGDWI/Rz09606 rogid:JVg1xMDlUm2RuG5VukrGDWI/Rz09606 rigid:zIE4a75DXjWsb8BjjFQhsgSIc30 false green fluorescent protein tag:c-c flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8IYM1 uniprotkb:Q8IYM1 intact:EBI-2585067|uniprotkb:Q96LL0|uniprotkb:Q0P6B0|uniprotkb:Q1PBH0|ensembl:ENSP00000268231 intact:EBI-2585067|uniprotkb:Q96LL0|uniprotkb:Q0P6B0|uniprotkb:Q1PBH0|ensembl:ENSP00000268231 psi-mi:sep12_human(display_long)|uniprotkb:SEPTIN12(gene name)|psi-mi:SEPTIN12(display_short)|uniprotkb:SEPT12(gene name synonym) psi-mi:sep12_human(display_long)|uniprotkb:SEPTIN12(gene name)|psi-mi:SEPTIN12(display_short)|uniprotkb:SEPT12(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2015) pubmed:25588830|imex:IM-25619 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-12598705|imex:IM-25619-24 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001147930.1|refseq:NP_653206.2|refseq:XP_006720909.1|ensembl:ENSG00000140623(gene)|ensembl:ENST00000268231(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097227"(sperm annulus)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:6MQ9|rcsb pdb:6MQB|rcsb pdb:6MQK|rcsb pdb:6MQL refseq:NP_001147930.1|refseq:NP_653206.2|refseq:XP_006720909.1|ensembl:ENSG00000140623(gene)|ensembl:ENST00000268231(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097227"(sperm annulus)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:6MQ9|rcsb pdb:6MQB|rcsb pdb:6MQK|rcsb pdb:6MQL - - - figure legend:5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-nt2d1)|taxid:9606("human NTERA-2 d.D1 (NT2D1) testicular embryonal carcinoma cell line") - 2016/11/16 2016/11/17 rogid:JVg1xMDlUm2RuG5VukrGDWI/Rz09606 rogid:JVg1xMDlUm2RuG5VukrGDWI/Rz09606 rigid:zIE4a75DXjWsb8BjjFQhsgSIc30 false green fluorescent protein tag:c-c flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8IYM1 uniprotkb:Q8IYM1 intact:EBI-2585067|uniprotkb:Q96LL0|uniprotkb:Q0P6B0|uniprotkb:Q1PBH0|ensembl:ENSP00000268231 intact:EBI-2585067|uniprotkb:Q96LL0|uniprotkb:Q0P6B0|uniprotkb:Q1PBH0|ensembl:ENSP00000268231 psi-mi:sep12_human(display_long)|uniprotkb:SEPTIN12(gene name)|psi-mi:SEPTIN12(display_short)|uniprotkb:SEPT12(gene name synonym) psi-mi:sep12_human(display_long)|uniprotkb:SEPTIN12(gene name)|psi-mi:SEPTIN12(display_short)|uniprotkb:SEPT12(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2015) pubmed:25588830|imex:IM-25619 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-12598713|imex:IM-25619-25 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001147930.1|refseq:NP_653206.2|refseq:XP_006720909.1|ensembl:ENSG00000140623(gene)|ensembl:ENST00000268231(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097227"(sperm annulus)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:6MQ9|rcsb pdb:6MQB|rcsb pdb:6MQK|rcsb pdb:6MQL refseq:NP_001147930.1|refseq:NP_653206.2|refseq:XP_006720909.1|ensembl:ENSG00000140623(gene)|ensembl:ENST00000268231(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097227"(sperm annulus)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:6MQ9|rcsb pdb:6MQB|rcsb pdb:6MQK|rcsb pdb:6MQL - - - figure legend:5B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-nt2d1)|taxid:9606("human NTERA-2 d.D1 (NT2D1) testicular embryonal carcinoma cell line") - 2016/11/16 2016/11/17 rogid:JVg1xMDlUm2RuG5VukrGDWI/Rz09606 rogid:JVg1xMDlUm2RuG5VukrGDWI/Rz09606 rigid:zIE4a75DXjWsb8BjjFQhsgSIc30 false myc tag:c-c|sufficient binding region:258-358 flag tag:c-c|sufficient binding region:258-358 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8IYM1 uniprotkb:Q8IYM1 intact:EBI-2585067|uniprotkb:Q96LL0|uniprotkb:Q0P6B0|uniprotkb:Q1PBH0|ensembl:ENSP00000268231 intact:EBI-2585067|uniprotkb:Q96LL0|uniprotkb:Q0P6B0|uniprotkb:Q1PBH0|ensembl:ENSP00000268231 psi-mi:sep12_human(display_long)|uniprotkb:SEPTIN12(gene name)|psi-mi:SEPTIN12(display_short)|uniprotkb:SEPT12(gene name synonym) psi-mi:sep12_human(display_long)|uniprotkb:SEPTIN12(gene name)|psi-mi:SEPTIN12(display_short)|uniprotkb:SEPT12(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2015) pubmed:25588830|imex:IM-25619 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-12598725|imex:IM-25619-26 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001147930.1|refseq:NP_653206.2|refseq:XP_006720909.1|ensembl:ENSG00000140623(gene)|ensembl:ENST00000268231(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097227"(sperm annulus)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:6MQ9|rcsb pdb:6MQB|rcsb pdb:6MQK|rcsb pdb:6MQL refseq:NP_001147930.1|refseq:NP_653206.2|refseq:XP_006720909.1|ensembl:ENSG00000140623(gene)|ensembl:ENST00000268231(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097227"(sperm annulus)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:6MQ9|rcsb pdb:6MQB|rcsb pdb:6MQK|rcsb pdb:6MQL - - - figure legend:5B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-nt2d1)|taxid:9606("human NTERA-2 d.D1 (NT2D1) testicular embryonal carcinoma cell line") - 2016/11/16 2016/11/17 rogid:JVg1xMDlUm2RuG5VukrGDWI/Rz09606 rogid:JVg1xMDlUm2RuG5VukrGDWI/Rz09606 rigid:zIE4a75DXjWsb8BjjFQhsgSIc30 false myc tag:c-c|sufficient binding region:258-358 flag tag:c-c|sufficient binding region:258-358 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8IYM1 uniprotkb:Q8IYM1 intact:EBI-2585067|uniprotkb:Q96LL0|uniprotkb:Q0P6B0|uniprotkb:Q1PBH0|ensembl:ENSP00000268231 intact:EBI-2585067|uniprotkb:Q96LL0|uniprotkb:Q0P6B0|uniprotkb:Q1PBH0|ensembl:ENSP00000268231 psi-mi:sep12_human(display_long)|uniprotkb:SEPTIN12(gene name)|psi-mi:SEPTIN12(display_short)|uniprotkb:SEPT12(gene name synonym) psi-mi:sep12_human(display_long)|uniprotkb:SEPTIN12(gene name)|psi-mi:SEPTIN12(display_short)|uniprotkb:SEPT12(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2015) pubmed:25588830|imex:IM-25619 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-12598737|imex:IM-25619-27 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001147930.1|refseq:NP_653206.2|refseq:XP_006720909.1|ensembl:ENSG00000140623(gene)|ensembl:ENST00000268231(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097227"(sperm annulus)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:6MQ9|rcsb pdb:6MQB|rcsb pdb:6MQK|rcsb pdb:6MQL refseq:NP_001147930.1|refseq:NP_653206.2|refseq:XP_006720909.1|ensembl:ENSG00000140623(gene)|ensembl:ENST00000268231(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097227"(sperm annulus)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:6MQ9|rcsb pdb:6MQB|rcsb pdb:6MQK|rcsb pdb:6MQL - - - figure legend:5C|antagonist:High salt conditions|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-nt2d1)|taxid:9606("human NTERA-2 d.D1 (NT2D1) testicular embryonal carcinoma cell line") - 2016/11/16 2016/11/17 rogid:JVg1xMDlUm2RuG5VukrGDWI/Rz09606 rogid:JVg1xMDlUm2RuG5VukrGDWI/Rz09606 rigid:zIE4a75DXjWsb8BjjFQhsgSIc30 false ha tag:n-n|sufficient binding region:258-358 flag tag:c-c|sufficient binding region:258-358 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8IYM1 uniprotkb:Q15019 intact:EBI-2585067|uniprotkb:Q96LL0|uniprotkb:Q0P6B0|uniprotkb:Q1PBH0|ensembl:ENSP00000268231 intact:EBI-741220|intact:EBI-28986019|ensembl:ENSP00000353157|ensembl:ENSP00000375832|ensembl:ENSP00000375834|ensembl:ENSP00000385172|uniprotkb:Q14132|uniprotkb:Q8IUK9|uniprotkb:Q96CB0|uniprotkb:B4DGE8|uniprotkb:Q53QU3 psi-mi:sep12_human(display_long)|uniprotkb:SEPTIN12(gene name)|psi-mi:SEPTIN12(display_short)|uniprotkb:SEPT12(gene name synonym) psi-mi:sept2_human(display_long)|uniprotkb:SEPTIN2(gene name)|psi-mi:SEPTIN2(display_short)|uniprotkb:DIFF6(gene name synonym)|uniprotkb:KIAA0158(gene name synonym)|uniprotkb:NEDD5(gene name synonym)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 5(gene name synonym)|uniprotkb:SEPT2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2015) pubmed:25588830|imex:IM-25619 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-12598750|imex:IM-25619-28 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001147930.1|refseq:NP_653206.2|refseq:XP_006720909.1|ensembl:ENSG00000140623(gene)|ensembl:ENST00000268231(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097227"(sperm annulus)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:6MQ9|rcsb pdb:6MQB|rcsb pdb:6MQK|rcsb pdb:6MQL refseq:NP_001269901.1|refseq:NP_001269902.1|ensembl:ENSG00000168385(gene)|ensembl:ENST00000360051(transcript)|ensembl:ENST00000391971(transcript)|ensembl:ENST00000391973(transcript)|ensembl:ENST00000402092(transcript)|go:"GO:0000145"(exocyst)|go:"GO:0000776"(kinetochore)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005886"(plasma membrane)|go:"GO:0005930"(axoneme)|go:"GO:0005940"(septin ring)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042802"(identical protein binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045296"(cadherin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097227"(sperm annulus)|go:"GO:0097730"(non-motile cilium)|interpro:IPR008113(Septin 2)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|mint:Q15019|rcsb pdb:2QA5|rcsb pdb:2QAG|rcsb pdb:2QNR|rcsb pdb:6UPA|rcsb pdb:6UPQ|rcsb pdb:6UPR|reactome:R-HSA-5620912|refseq:NP_001008491.1|refseq:NP_001008492.1|refseq:NP_004395.1|refseq:NP_006146.1|refseq:XP_016859694.1|refseq:XP_016859695.1|refseq:NP_001307958.1|refseq:NP_001307959.1|refseq:NP_001307960.1|refseq:NP_001307961.1|refseq:NP_001307962.1|refseq:NP_001307963.1|refseq:NP_001307964.1|ensembl:ENSP00000353157|ensembl:ENSP00000375832|ensembl:ENSP00000375834|ensembl:ENST00000401990|ensembl:ENSP00000385109|ensembl:ENSP00000385172|ensembl:ENST00000616972|ensembl:ENSP00000479861|dip:DIP-38220N - - crc64:12CCBBE30806F92F figure legend:5D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-nt2d1)|taxid:9606("human NTERA-2 d.D1 (NT2D1) testicular embryonal carcinoma cell line") - 2016/11/16 2016/11/17 rogid:JVg1xMDlUm2RuG5VukrGDWI/Rz09606 rogid:H0Us8GtPe2XuXlOYXC0DX79kB/49606 rigid:n1KcggPw+D6XHOstI1iAKEwLJ6E false green fluorescent protein tag:n-n|sufficient binding region:46-319(IPR030379) - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8IYM1 uniprotkb:Q14141 intact:EBI-2585067|uniprotkb:Q96LL0|uniprotkb:Q0P6B0|uniprotkb:Q1PBH0|ensembl:ENSP00000268231 intact:EBI-745901|uniprotkb:Q5JTK0|uniprotkb:Q969W5|uniprotkb:Q96A13|uniprotkb:Q96GR1|uniprotkb:Q96P86|uniprotkb:Q96P87|intact:EBI-1047521|ensembl:ENSP00000341524 psi-mi:sep12_human(display_long)|uniprotkb:SEPTIN12(gene name)|psi-mi:SEPTIN12(display_short)|uniprotkb:SEPT12(gene name synonym) psi-mi:sept6_human(display_long)|uniprotkb:SEPTIN6(gene name)|psi-mi:SEPTIN6(display_short)|uniprotkb:KIAA0128(gene name synonym)|uniprotkb:SEP2(gene name synonym)|uniprotkb:SEPT6(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2015) pubmed:25588830|imex:IM-25619 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-12598750|imex:IM-25619-28 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001147930.1|refseq:NP_653206.2|refseq:XP_006720909.1|ensembl:ENSG00000140623(gene)|ensembl:ENST00000268231(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097227"(sperm annulus)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:6MQ9|rcsb pdb:6MQB|rcsb pdb:6MQK|rcsb pdb:6MQL ensembl:ENSG00000125354(gene)|ensembl:ENST00000343984(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000776"(kinetochore)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005819"(spindle)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032173"(septin collar)|go:"GO:0034613"(cellular protein localization)|go:"GO:0043679"(axon terminus)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097227"(sperm annulus)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|interpro:IPR030644|mint:Q14141|rcsb pdb:2QAG|rcsb pdb:6UPA|rcsb pdb:6WBP|refseq:NP_055944.2|refseq:NP_665798.1|refseq:NP_665799.1|refseq:NP_665801.1|refseq:XP_006724813.1|dip:DIP-38218N - - - figure legend:5D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-nt2d1)|taxid:9606("human NTERA-2 d.D1 (NT2D1) testicular embryonal carcinoma cell line") - 2016/11/16 2016/11/17 rogid:JVg1xMDlUm2RuG5VukrGDWI/Rz09606 rogid:gH1JHXyE/7o3I8i4ZS3bMoF7zvU9606 rigid:n1KcggPw+D6XHOstI1iAKEwLJ6E false green fluorescent protein tag:n-n|sufficient binding region:46-319(IPR030379) myc tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8IYM1 uniprotkb:Q16181 intact:EBI-2585067|uniprotkb:Q96LL0|uniprotkb:Q0P6B0|uniprotkb:Q1PBH0|ensembl:ENSP00000268231 intact:EBI-2009373|uniprotkb:Q52M76|uniprotkb:Q6NX50|ensembl:ENSP00000381992 psi-mi:sep12_human(display_long)|uniprotkb:SEPTIN12(gene name)|psi-mi:SEPTIN12(display_short)|uniprotkb:SEPT12(gene name synonym) psi-mi:sept7_human(display_long)|uniprotkb:SEPTIN7(gene name)|psi-mi:SEPTIN7(display_short)|uniprotkb:CDC10(gene name synonym)|uniprotkb:CDC10 protein homolog(gene name synonym)|uniprotkb:SEPT7(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2015) pubmed:25588830|imex:IM-25619 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-12598750|imex:IM-25619-28 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001147930.1|refseq:NP_653206.2|refseq:XP_006720909.1|ensembl:ENSG00000140623(gene)|ensembl:ENST00000268231(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097227"(sperm annulus)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:6MQ9|rcsb pdb:6MQB|rcsb pdb:6MQK|rcsb pdb:6MQL refseq:NP_001779.3|dip:DIP-47093N|ensembl:ENSG00000122545(gene)|ensembl:ENST00000399034(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016476"(regulation of embryonic cell shape)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097227"(sperm annulus)|go:"GO:0097730"(non-motile cilium)|go:"GO:1902857"(positive regulation of non-motile cilium assembly)|interpro:IPR008115(Septin 7)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:2QAG|rcsb pdb:3T5D|rcsb pdb:3TW4|rcsb pdb:6N0B|rcsb pdb:6N12|rcsb pdb:6UQQ|reactome:R-HSA-5687128 - - - figure legend:5D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-nt2d1)|taxid:9606("human NTERA-2 d.D1 (NT2D1) testicular embryonal carcinoma cell line") - 2016/11/16 2016/11/17 rogid:JVg1xMDlUm2RuG5VukrGDWI/Rz09606 rogid:CweIjGLXC7eubvKR7vkkihEkcHg9606 rigid:n1KcggPw+D6XHOstI1iAKEwLJ6E false green fluorescent protein tag:n-n|sufficient binding region:46-319(IPR030379) flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q15019 uniprotkb:Q8IYM1 intact:EBI-741220|intact:EBI-28986019|ensembl:ENSP00000353157|ensembl:ENSP00000375832|ensembl:ENSP00000375834|ensembl:ENSP00000385172|uniprotkb:Q14132|uniprotkb:Q8IUK9|uniprotkb:Q96CB0|uniprotkb:B4DGE8|uniprotkb:Q53QU3 intact:EBI-2585067|uniprotkb:Q96LL0|uniprotkb:Q0P6B0|uniprotkb:Q1PBH0|ensembl:ENSP00000268231 psi-mi:sept2_human(display_long)|uniprotkb:SEPTIN2(gene name)|psi-mi:SEPTIN2(display_short)|uniprotkb:DIFF6(gene name synonym)|uniprotkb:KIAA0158(gene name synonym)|uniprotkb:NEDD5(gene name synonym)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 5(gene name synonym)|uniprotkb:SEPT2(gene name synonym) psi-mi:sep12_human(display_long)|uniprotkb:SEPTIN12(gene name)|psi-mi:SEPTIN12(display_short)|uniprotkb:SEPT12(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2015) pubmed:25588830|imex:IM-25619 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-12598482|imex:IM-25619-12 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001269901.1|refseq:NP_001269902.1|ensembl:ENSG00000168385(gene)|ensembl:ENST00000360051(transcript)|ensembl:ENST00000391971(transcript)|ensembl:ENST00000391973(transcript)|ensembl:ENST00000402092(transcript)|go:"GO:0000145"(exocyst)|go:"GO:0000776"(kinetochore)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005886"(plasma membrane)|go:"GO:0005930"(axoneme)|go:"GO:0005940"(septin ring)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042802"(identical protein binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045296"(cadherin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097227"(sperm annulus)|go:"GO:0097730"(non-motile cilium)|interpro:IPR008113(Septin 2)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|mint:Q15019|rcsb pdb:2QA5|rcsb pdb:2QAG|rcsb pdb:2QNR|rcsb pdb:6UPA|rcsb pdb:6UPQ|rcsb pdb:6UPR|reactome:R-HSA-5620912|refseq:NP_001008491.1|refseq:NP_001008492.1|refseq:NP_004395.1|refseq:NP_006146.1|refseq:XP_016859694.1|refseq:XP_016859695.1|refseq:NP_001307958.1|refseq:NP_001307959.1|refseq:NP_001307960.1|refseq:NP_001307961.1|refseq:NP_001307962.1|refseq:NP_001307963.1|refseq:NP_001307964.1|ensembl:ENSP00000353157|ensembl:ENSP00000375832|ensembl:ENSP00000375834|ensembl:ENST00000401990|ensembl:ENSP00000385109|ensembl:ENSP00000385172|ensembl:ENST00000616972|ensembl:ENSP00000479861|dip:DIP-38220N refseq:NP_001147930.1|refseq:NP_653206.2|refseq:XP_006720909.1|ensembl:ENSG00000140623(gene)|ensembl:ENST00000268231(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097227"(sperm annulus)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:6MQ9|rcsb pdb:6MQB|rcsb pdb:6MQK|rcsb pdb:6MQL - crc64:12CCBBE30806F92F - figure legend:2A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-nt2d1)|taxid:9606("human NTERA-2 d.D1 (NT2D1) testicular embryonal carcinoma cell line") - 2016/11/16 2016/11/16 rogid:H0Us8GtPe2XuXlOYXC0DX79kB/49606 rogid:JVg1xMDlUm2RuG5VukrGDWI/Rz09606 rigid:A4bByG4ap2elejkOD6pQ47/pty4 false - green fluorescent protein tag:c-c - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q16181 uniprotkb:Q8IYM1 intact:EBI-2009373|uniprotkb:Q52M76|uniprotkb:Q6NX50|ensembl:ENSP00000381992 intact:EBI-2585067|uniprotkb:Q96LL0|uniprotkb:Q0P6B0|uniprotkb:Q1PBH0|ensembl:ENSP00000268231 psi-mi:sept7_human(display_long)|uniprotkb:SEPTIN7(gene name)|psi-mi:SEPTIN7(display_short)|uniprotkb:CDC10(gene name synonym)|uniprotkb:CDC10 protein homolog(gene name synonym)|uniprotkb:SEPT7(gene name synonym) psi-mi:sep12_human(display_long)|uniprotkb:SEPTIN12(gene name)|psi-mi:SEPTIN12(display_short)|uniprotkb:SEPT12(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Kuo et al. (2015) pubmed:25588830|imex:IM-25619 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-12598497|imex:IM-25619-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001779.3|dip:DIP-47093N|ensembl:ENSG00000122545(gene)|ensembl:ENST00000399034(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016476"(regulation of embryonic cell shape)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097227"(sperm annulus)|go:"GO:0097730"(non-motile cilium)|go:"GO:1902857"(positive regulation of non-motile cilium assembly)|interpro:IPR008115(Septin 7)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:2QAG|rcsb pdb:3T5D|rcsb pdb:3TW4|rcsb pdb:6N0B|rcsb pdb:6N12|rcsb pdb:6UQQ|reactome:R-HSA-5687128 refseq:NP_001147930.1|refseq:NP_653206.2|refseq:XP_006720909.1|ensembl:ENSG00000140623(gene)|ensembl:ENST00000268231(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097227"(sperm annulus)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:6MQ9|rcsb pdb:6MQB|rcsb pdb:6MQK|rcsb pdb:6MQL go:"GO:0005737"(cytoplasm)|go:"GO:0099512"(supramolecular fiber) - - figure legend:2C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-nt2d1)|taxid:9606("human NTERA-2 d.D1 (NT2D1) testicular embryonal carcinoma cell line") - 2016/11/16 2016/11/16 rogid:CweIjGLXC7eubvKR7vkkihEkcHg9606 rogid:JVg1xMDlUm2RuG5VukrGDWI/Rz09606 rigid:hDfziRCIGAQdBG6Yaq7Pa2Z74Ac false myc tag:n-n green fluorescent protein tag:c-c - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:Q14141 uniprotkb:Q8IYM1 intact:EBI-745901|uniprotkb:Q5JTK0|uniprotkb:Q969W5|uniprotkb:Q96A13|uniprotkb:Q96GR1|uniprotkb:Q96P86|uniprotkb:Q96P87|intact:EBI-1047521|ensembl:ENSP00000341524 intact:EBI-2585067|uniprotkb:Q96LL0|uniprotkb:Q0P6B0|uniprotkb:Q1PBH0|ensembl:ENSP00000268231 psi-mi:sept6_human(display_long)|uniprotkb:SEPTIN6(gene name)|psi-mi:SEPTIN6(display_short)|uniprotkb:KIAA0128(gene name synonym)|uniprotkb:SEP2(gene name synonym)|uniprotkb:SEPT6(gene name synonym) psi-mi:sep12_human(display_long)|uniprotkb:SEPTIN12(gene name)|psi-mi:SEPTIN12(display_short)|uniprotkb:SEPT12(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Kuo et al. (2015) pubmed:25588830|imex:IM-25619 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-12598508|imex:IM-25619-14 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000125354(gene)|ensembl:ENST00000343984(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000776"(kinetochore)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005819"(spindle)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032173"(septin collar)|go:"GO:0034613"(cellular protein localization)|go:"GO:0043679"(axon terminus)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097227"(sperm annulus)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|interpro:IPR030644|mint:Q14141|rcsb pdb:2QAG|rcsb pdb:6UPA|rcsb pdb:6WBP|refseq:NP_055944.2|refseq:NP_665798.1|refseq:NP_665799.1|refseq:NP_665801.1|refseq:XP_006724813.1|dip:DIP-38218N refseq:NP_001147930.1|refseq:NP_653206.2|refseq:XP_006720909.1|ensembl:ENSG00000140623(gene)|ensembl:ENST00000268231(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097227"(sperm annulus)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:6MQ9|rcsb pdb:6MQB|rcsb pdb:6MQK|rcsb pdb:6MQL go:"GO:0005737"(cytoplasm)|go:"GO:0099512"(supramolecular fiber) - - figure legend:2C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-nt2d1)|taxid:9606("human NTERA-2 d.D1 (NT2D1) testicular embryonal carcinoma cell line") - 2016/11/16 2016/11/16 rogid:gH1JHXyE/7o3I8i4ZS3bMoF7zvU9606 rogid:JVg1xMDlUm2RuG5VukrGDWI/Rz09606 rigid:fh0B7vzVkq+giBNXe3VL1MJsKUo false myc tag:c-c green fluorescent protein tag:c-c - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:Q15019 uniprotkb:Q8IYM1 intact:EBI-741220|intact:EBI-28986019|ensembl:ENSP00000353157|ensembl:ENSP00000375832|ensembl:ENSP00000375834|ensembl:ENSP00000385172|uniprotkb:Q14132|uniprotkb:Q8IUK9|uniprotkb:Q96CB0|uniprotkb:B4DGE8|uniprotkb:Q53QU3 intact:EBI-2585067|uniprotkb:Q96LL0|uniprotkb:Q0P6B0|uniprotkb:Q1PBH0|ensembl:ENSP00000268231 psi-mi:sept2_human(display_long)|uniprotkb:SEPTIN2(gene name)|psi-mi:SEPTIN2(display_short)|uniprotkb:DIFF6(gene name synonym)|uniprotkb:KIAA0158(gene name synonym)|uniprotkb:NEDD5(gene name synonym)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 5(gene name synonym)|uniprotkb:SEPT2(gene name synonym) psi-mi:sep12_human(display_long)|uniprotkb:SEPTIN12(gene name)|psi-mi:SEPTIN12(display_short)|uniprotkb:SEPT12(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Kuo et al. (2015) pubmed:25588830|imex:IM-25619 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-12598517|imex:IM-25619-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001269901.1|refseq:NP_001269902.1|ensembl:ENSG00000168385(gene)|ensembl:ENST00000360051(transcript)|ensembl:ENST00000391971(transcript)|ensembl:ENST00000391973(transcript)|ensembl:ENST00000402092(transcript)|go:"GO:0000145"(exocyst)|go:"GO:0000776"(kinetochore)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005886"(plasma membrane)|go:"GO:0005930"(axoneme)|go:"GO:0005940"(septin ring)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042802"(identical protein binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045296"(cadherin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097227"(sperm annulus)|go:"GO:0097730"(non-motile cilium)|interpro:IPR008113(Septin 2)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|mint:Q15019|rcsb pdb:2QA5|rcsb pdb:2QAG|rcsb pdb:2QNR|rcsb pdb:6UPA|rcsb pdb:6UPQ|rcsb pdb:6UPR|reactome:R-HSA-5620912|refseq:NP_001008491.1|refseq:NP_001008492.1|refseq:NP_004395.1|refseq:NP_006146.1|refseq:XP_016859694.1|refseq:XP_016859695.1|refseq:NP_001307958.1|refseq:NP_001307959.1|refseq:NP_001307960.1|refseq:NP_001307961.1|refseq:NP_001307962.1|refseq:NP_001307963.1|refseq:NP_001307964.1|ensembl:ENSP00000353157|ensembl:ENSP00000375832|ensembl:ENSP00000375834|ensembl:ENST00000401990|ensembl:ENSP00000385109|ensembl:ENSP00000385172|ensembl:ENST00000616972|ensembl:ENSP00000479861|dip:DIP-38220N refseq:NP_001147930.1|refseq:NP_653206.2|refseq:XP_006720909.1|ensembl:ENSG00000140623(gene)|ensembl:ENST00000268231(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097227"(sperm annulus)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:6MQ9|rcsb pdb:6MQB|rcsb pdb:6MQK|rcsb pdb:6MQL go:"GO:0005737"(cytoplasm)|go:"GO:0099512"(supramolecular fiber) crc64:12CCBBE30806F92F - figure legend:2C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-nt2d1)|taxid:9606("human NTERA-2 d.D1 (NT2D1) testicular embryonal carcinoma cell line") - 2016/11/16 2016/11/16 rogid:H0Us8GtPe2XuXlOYXC0DX79kB/49606 rogid:JVg1xMDlUm2RuG5VukrGDWI/Rz09606 rigid:A4bByG4ap2elejkOD6pQ47/pty4 false - green fluorescent protein tag:c-c - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:Q16181 uniprotkb:Q8IYM1 intact:EBI-2009373|uniprotkb:Q52M76|uniprotkb:Q6NX50|ensembl:ENSP00000381992 intact:EBI-2585067|uniprotkb:Q96LL0|uniprotkb:Q0P6B0|uniprotkb:Q1PBH0|ensembl:ENSP00000268231 psi-mi:sept7_human(display_long)|uniprotkb:SEPTIN7(gene name)|psi-mi:SEPTIN7(display_short)|uniprotkb:CDC10(gene name synonym)|uniprotkb:CDC10 protein homolog(gene name synonym)|uniprotkb:SEPT7(gene name synonym) psi-mi:sep12_human(display_long)|uniprotkb:SEPTIN12(gene name)|psi-mi:SEPTIN12(display_short)|uniprotkb:SEPT12(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Kuo et al. (2015) pubmed:25588830|imex:IM-25619 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-12598664|imex:IM-25619-21 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001779.3|dip:DIP-47093N|ensembl:ENSG00000122545(gene)|ensembl:ENST00000399034(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016476"(regulation of embryonic cell shape)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097227"(sperm annulus)|go:"GO:0097730"(non-motile cilium)|go:"GO:1902857"(positive regulation of non-motile cilium assembly)|interpro:IPR008115(Septin 7)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:2QAG|rcsb pdb:3T5D|rcsb pdb:3TW4|rcsb pdb:6N0B|rcsb pdb:6N12|rcsb pdb:6UQQ|reactome:R-HSA-5687128 refseq:NP_001147930.1|refseq:NP_653206.2|refseq:XP_006720909.1|ensembl:ENSG00000140623(gene)|ensembl:ENST00000268231(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097227"(sperm annulus)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:6MQ9|rcsb pdb:6MQB|rcsb pdb:6MQK|rcsb pdb:6MQL omim:614822(see-also) - - figure legend:4E|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-nt2d1)|taxid:9606("human NTERA-2 d.D1 (NT2D1) testicular embryonal carcinoma cell line") - 2016/11/16 2016/11/17 rogid:CweIjGLXC7eubvKR7vkkihEkcHg9606 rogid:JVg1xMDlUm2RuG5VukrGDWI/Rz09606 rigid:hDfziRCIGAQdBG6Yaq7Pa2Z74Ac false flag tag:n-n green fluorescent protein tag:c-c|mutation decreasing interaction:89-89|mutation disrupting interaction:197-197 - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q8IYM1 uniprotkb:Q15019 intact:EBI-2585067|uniprotkb:Q96LL0|uniprotkb:Q0P6B0|uniprotkb:Q1PBH0|ensembl:ENSP00000268231 intact:EBI-741220|intact:EBI-28986019|ensembl:ENSP00000353157|ensembl:ENSP00000375832|ensembl:ENSP00000375834|ensembl:ENSP00000385172|uniprotkb:Q14132|uniprotkb:Q8IUK9|uniprotkb:Q96CB0|uniprotkb:B4DGE8|uniprotkb:Q53QU3 psi-mi:sep12_human(display_long)|uniprotkb:SEPTIN12(gene name)|psi-mi:SEPTIN12(display_short)|uniprotkb:SEPT12(gene name synonym) psi-mi:sept2_human(display_long)|uniprotkb:SEPTIN2(gene name)|psi-mi:SEPTIN2(display_short)|uniprotkb:DIFF6(gene name synonym)|uniprotkb:KIAA0158(gene name synonym)|uniprotkb:NEDD5(gene name synonym)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 5(gene name synonym)|uniprotkb:SEPT2(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Kuo et al. (2015) pubmed:25588830|imex:IM-25619 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-12598676|imex:IM-25619-22 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001147930.1|refseq:NP_653206.2|refseq:XP_006720909.1|ensembl:ENSG00000140623(gene)|ensembl:ENST00000268231(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097227"(sperm annulus)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:6MQ9|rcsb pdb:6MQB|rcsb pdb:6MQK|rcsb pdb:6MQL refseq:NP_001269901.1|refseq:NP_001269902.1|ensembl:ENSG00000168385(gene)|ensembl:ENST00000360051(transcript)|ensembl:ENST00000391971(transcript)|ensembl:ENST00000391973(transcript)|ensembl:ENST00000402092(transcript)|go:"GO:0000145"(exocyst)|go:"GO:0000776"(kinetochore)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005886"(plasma membrane)|go:"GO:0005930"(axoneme)|go:"GO:0005940"(septin ring)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042802"(identical protein binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045296"(cadherin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097227"(sperm annulus)|go:"GO:0097730"(non-motile cilium)|interpro:IPR008113(Septin 2)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|mint:Q15019|rcsb pdb:2QA5|rcsb pdb:2QAG|rcsb pdb:2QNR|rcsb pdb:6UPA|rcsb pdb:6UPQ|rcsb pdb:6UPR|reactome:R-HSA-5620912|refseq:NP_001008491.1|refseq:NP_001008492.1|refseq:NP_004395.1|refseq:NP_006146.1|refseq:XP_016859694.1|refseq:XP_016859695.1|refseq:NP_001307958.1|refseq:NP_001307959.1|refseq:NP_001307960.1|refseq:NP_001307961.1|refseq:NP_001307962.1|refseq:NP_001307963.1|refseq:NP_001307964.1|ensembl:ENSP00000353157|ensembl:ENSP00000375832|ensembl:ENSP00000375834|ensembl:ENST00000401990|ensembl:ENSP00000385109|ensembl:ENSP00000385172|ensembl:ENST00000616972|ensembl:ENSP00000479861|dip:DIP-38220N omim:614822(see-also)|go:"GO:0099512"(supramolecular fiber) comment:"A SEPT12 construct 46-319 (missing the N and C termini) disrupts the colocalization" crc64:12CCBBE30806F92F figure legend:4F, 5E|comment:SEPT12-GBD disrupted filament formation for all four septins.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-nt2d1)|taxid:9606("human NTERA-2 d.D1 (NT2D1) testicular embryonal carcinoma cell line") - 2016/11/16 2016/11/17 rogid:JVg1xMDlUm2RuG5VukrGDWI/Rz09606 rogid:H0Us8GtPe2XuXlOYXC0DX79kB/49606 rigid:n1KcggPw+D6XHOstI1iAKEwLJ6E false necessary binding region:1-45,320-358|green fluorescent protein tag:c-c|mutation decreasing interaction:89-89|mutation disrupting interaction:197-197 - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q8IYM1 uniprotkb:Q14141 intact:EBI-2585067|uniprotkb:Q96LL0|uniprotkb:Q0P6B0|uniprotkb:Q1PBH0|ensembl:ENSP00000268231 intact:EBI-745901|uniprotkb:Q5JTK0|uniprotkb:Q969W5|uniprotkb:Q96A13|uniprotkb:Q96GR1|uniprotkb:Q96P86|uniprotkb:Q96P87|intact:EBI-1047521|ensembl:ENSP00000341524 psi-mi:sep12_human(display_long)|uniprotkb:SEPTIN12(gene name)|psi-mi:SEPTIN12(display_short)|uniprotkb:SEPT12(gene name synonym) psi-mi:sept6_human(display_long)|uniprotkb:SEPTIN6(gene name)|psi-mi:SEPTIN6(display_short)|uniprotkb:KIAA0128(gene name synonym)|uniprotkb:SEP2(gene name synonym)|uniprotkb:SEPT6(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Kuo et al. (2015) pubmed:25588830|imex:IM-25619 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-12598676|imex:IM-25619-22 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001147930.1|refseq:NP_653206.2|refseq:XP_006720909.1|ensembl:ENSG00000140623(gene)|ensembl:ENST00000268231(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097227"(sperm annulus)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:6MQ9|rcsb pdb:6MQB|rcsb pdb:6MQK|rcsb pdb:6MQL ensembl:ENSG00000125354(gene)|ensembl:ENST00000343984(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000776"(kinetochore)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005819"(spindle)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032173"(septin collar)|go:"GO:0034613"(cellular protein localization)|go:"GO:0043679"(axon terminus)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097227"(sperm annulus)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|interpro:IPR030644|mint:Q14141|rcsb pdb:2QAG|rcsb pdb:6UPA|rcsb pdb:6WBP|refseq:NP_055944.2|refseq:NP_665798.1|refseq:NP_665799.1|refseq:NP_665801.1|refseq:XP_006724813.1|dip:DIP-38218N omim:614822(see-also)|go:"GO:0099512"(supramolecular fiber) comment:"A SEPT12 construct 46-319 (missing the N and C termini) disrupts the colocalization" - figure legend:4F, 5E|comment:SEPT12-GBD disrupted filament formation for all four septins.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-nt2d1)|taxid:9606("human NTERA-2 d.D1 (NT2D1) testicular embryonal carcinoma cell line") - 2016/11/16 2016/11/17 rogid:JVg1xMDlUm2RuG5VukrGDWI/Rz09606 rogid:gH1JHXyE/7o3I8i4ZS3bMoF7zvU9606 rigid:n1KcggPw+D6XHOstI1iAKEwLJ6E false necessary binding region:1-45,320-358|green fluorescent protein tag:c-c|mutation decreasing interaction:89-89|mutation disrupting interaction:197-197 myc tag:c-c - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q8IYM1 uniprotkb:Q16181 intact:EBI-2585067|uniprotkb:Q96LL0|uniprotkb:Q0P6B0|uniprotkb:Q1PBH0|ensembl:ENSP00000268231 intact:EBI-2009373|uniprotkb:Q52M76|uniprotkb:Q6NX50|ensembl:ENSP00000381992 psi-mi:sep12_human(display_long)|uniprotkb:SEPTIN12(gene name)|psi-mi:SEPTIN12(display_short)|uniprotkb:SEPT12(gene name synonym) psi-mi:sept7_human(display_long)|uniprotkb:SEPTIN7(gene name)|psi-mi:SEPTIN7(display_short)|uniprotkb:CDC10(gene name synonym)|uniprotkb:CDC10 protein homolog(gene name synonym)|uniprotkb:SEPT7(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Kuo et al. (2015) pubmed:25588830|imex:IM-25619 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-12598676|imex:IM-25619-22 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001147930.1|refseq:NP_653206.2|refseq:XP_006720909.1|ensembl:ENSG00000140623(gene)|ensembl:ENST00000268231(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097227"(sperm annulus)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:6MQ9|rcsb pdb:6MQB|rcsb pdb:6MQK|rcsb pdb:6MQL refseq:NP_001779.3|dip:DIP-47093N|ensembl:ENSG00000122545(gene)|ensembl:ENST00000399034(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016476"(regulation of embryonic cell shape)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097227"(sperm annulus)|go:"GO:0097730"(non-motile cilium)|go:"GO:1902857"(positive regulation of non-motile cilium assembly)|interpro:IPR008115(Septin 7)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:2QAG|rcsb pdb:3T5D|rcsb pdb:3TW4|rcsb pdb:6N0B|rcsb pdb:6N12|rcsb pdb:6UQQ|reactome:R-HSA-5687128 omim:614822(see-also)|go:"GO:0099512"(supramolecular fiber) comment:"A SEPT12 construct 46-319 (missing the N and C termini) disrupts the colocalization" - figure legend:4F, 5E|comment:SEPT12-GBD disrupted filament formation for all four septins.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-nt2d1)|taxid:9606("human NTERA-2 d.D1 (NT2D1) testicular embryonal carcinoma cell line") - 2016/11/16 2016/11/17 rogid:JVg1xMDlUm2RuG5VukrGDWI/Rz09606 rogid:CweIjGLXC7eubvKR7vkkihEkcHg9606 rigid:n1KcggPw+D6XHOstI1iAKEwLJ6E false necessary binding region:1-45,320-358|green fluorescent protein tag:c-c|mutation decreasing interaction:89-89|mutation disrupting interaction:197-197 flag tag:n-n - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q15019 uniprotkb:Q14141 intact:EBI-741220|intact:EBI-28986019|ensembl:ENSP00000353157|ensembl:ENSP00000375832|ensembl:ENSP00000375834|ensembl:ENSP00000385172|uniprotkb:Q14132|uniprotkb:Q8IUK9|uniprotkb:Q96CB0|uniprotkb:B4DGE8|uniprotkb:Q53QU3 intact:EBI-745901|uniprotkb:Q5JTK0|uniprotkb:Q969W5|uniprotkb:Q96A13|uniprotkb:Q96GR1|uniprotkb:Q96P86|uniprotkb:Q96P87|intact:EBI-1047521|ensembl:ENSP00000341524 psi-mi:sept2_human(display_long)|uniprotkb:SEPTIN2(gene name)|psi-mi:SEPTIN2(display_short)|uniprotkb:DIFF6(gene name synonym)|uniprotkb:KIAA0158(gene name synonym)|uniprotkb:NEDD5(gene name synonym)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 5(gene name synonym)|uniprotkb:SEPT2(gene name synonym) psi-mi:sept6_human(display_long)|uniprotkb:SEPTIN6(gene name)|psi-mi:SEPTIN6(display_short)|uniprotkb:KIAA0128(gene name synonym)|uniprotkb:SEP2(gene name synonym)|uniprotkb:SEPT6(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Kuo et al. (2015) pubmed:25588830|imex:IM-25619 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-12739249|imex:IM-25619-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001269901.1|refseq:NP_001269902.1|ensembl:ENSG00000168385(gene)|ensembl:ENST00000360051(transcript)|ensembl:ENST00000391971(transcript)|ensembl:ENST00000391973(transcript)|ensembl:ENST00000402092(transcript)|go:"GO:0000145"(exocyst)|go:"GO:0000776"(kinetochore)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005886"(plasma membrane)|go:"GO:0005930"(axoneme)|go:"GO:0005940"(septin ring)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042802"(identical protein binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045296"(cadherin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097227"(sperm annulus)|go:"GO:0097730"(non-motile cilium)|interpro:IPR008113(Septin 2)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|mint:Q15019|rcsb pdb:2QA5|rcsb pdb:2QAG|rcsb pdb:2QNR|rcsb pdb:6UPA|rcsb pdb:6UPQ|rcsb pdb:6UPR|reactome:R-HSA-5620912|refseq:NP_001008491.1|refseq:NP_001008492.1|refseq:NP_004395.1|refseq:NP_006146.1|refseq:XP_016859694.1|refseq:XP_016859695.1|refseq:NP_001307958.1|refseq:NP_001307959.1|refseq:NP_001307960.1|refseq:NP_001307961.1|refseq:NP_001307962.1|refseq:NP_001307963.1|refseq:NP_001307964.1|ensembl:ENSP00000353157|ensembl:ENSP00000375832|ensembl:ENSP00000375834|ensembl:ENST00000401990|ensembl:ENSP00000385109|ensembl:ENSP00000385172|ensembl:ENST00000616972|ensembl:ENSP00000479861|dip:DIP-38220N ensembl:ENSG00000125354(gene)|ensembl:ENST00000343984(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000776"(kinetochore)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005819"(spindle)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032173"(septin collar)|go:"GO:0034613"(cellular protein localization)|go:"GO:0043679"(axon terminus)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097227"(sperm annulus)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|interpro:IPR030644|mint:Q14141|rcsb pdb:2QAG|rcsb pdb:6UPA|rcsb pdb:6WBP|refseq:NP_055944.2|refseq:NP_665798.1|refseq:NP_665799.1|refseq:NP_665801.1|refseq:XP_006724813.1|dip:DIP-38218N omim:614822(see-also)|go:"GO:0099512"(supramolecular fiber) crc64:12CCBBE30806F92F - figure legend:4F|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-nt2d1)|taxid:9606("human NTERA-2 d.D1 (NT2D1) testicular embryonal carcinoma cell line") - 2016/11/16 2017/01/17 rogid:H0Us8GtPe2XuXlOYXC0DX79kB/49606 rogid:gH1JHXyE/7o3I8i4ZS3bMoF7zvU9606 rigid:f+fHwMdjRNrn265IovXHjdlp26s false - myc tag:c-c - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q15019 uniprotkb:Q16181 intact:EBI-741220|intact:EBI-28986019|ensembl:ENSP00000353157|ensembl:ENSP00000375832|ensembl:ENSP00000375834|ensembl:ENSP00000385172|uniprotkb:Q14132|uniprotkb:Q8IUK9|uniprotkb:Q96CB0|uniprotkb:B4DGE8|uniprotkb:Q53QU3 intact:EBI-2009373|uniprotkb:Q52M76|uniprotkb:Q6NX50|ensembl:ENSP00000381992 psi-mi:sept2_human(display_long)|uniprotkb:SEPTIN2(gene name)|psi-mi:SEPTIN2(display_short)|uniprotkb:DIFF6(gene name synonym)|uniprotkb:KIAA0158(gene name synonym)|uniprotkb:NEDD5(gene name synonym)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 5(gene name synonym)|uniprotkb:SEPT2(gene name synonym) psi-mi:sept7_human(display_long)|uniprotkb:SEPTIN7(gene name)|psi-mi:SEPTIN7(display_short)|uniprotkb:CDC10(gene name synonym)|uniprotkb:CDC10 protein homolog(gene name synonym)|uniprotkb:SEPT7(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Kuo et al. (2015) pubmed:25588830|imex:IM-25619 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-12739249|imex:IM-25619-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001269901.1|refseq:NP_001269902.1|ensembl:ENSG00000168385(gene)|ensembl:ENST00000360051(transcript)|ensembl:ENST00000391971(transcript)|ensembl:ENST00000391973(transcript)|ensembl:ENST00000402092(transcript)|go:"GO:0000145"(exocyst)|go:"GO:0000776"(kinetochore)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005886"(plasma membrane)|go:"GO:0005930"(axoneme)|go:"GO:0005940"(septin ring)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042802"(identical protein binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045296"(cadherin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097227"(sperm annulus)|go:"GO:0097730"(non-motile cilium)|interpro:IPR008113(Septin 2)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|mint:Q15019|rcsb pdb:2QA5|rcsb pdb:2QAG|rcsb pdb:2QNR|rcsb pdb:6UPA|rcsb pdb:6UPQ|rcsb pdb:6UPR|reactome:R-HSA-5620912|refseq:NP_001008491.1|refseq:NP_001008492.1|refseq:NP_004395.1|refseq:NP_006146.1|refseq:XP_016859694.1|refseq:XP_016859695.1|refseq:NP_001307958.1|refseq:NP_001307959.1|refseq:NP_001307960.1|refseq:NP_001307961.1|refseq:NP_001307962.1|refseq:NP_001307963.1|refseq:NP_001307964.1|ensembl:ENSP00000353157|ensembl:ENSP00000375832|ensembl:ENSP00000375834|ensembl:ENST00000401990|ensembl:ENSP00000385109|ensembl:ENSP00000385172|ensembl:ENST00000616972|ensembl:ENSP00000479861|dip:DIP-38220N refseq:NP_001779.3|dip:DIP-47093N|ensembl:ENSG00000122545(gene)|ensembl:ENST00000399034(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016476"(regulation of embryonic cell shape)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097227"(sperm annulus)|go:"GO:0097730"(non-motile cilium)|go:"GO:1902857"(positive regulation of non-motile cilium assembly)|interpro:IPR008115(Septin 7)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:2QAG|rcsb pdb:3T5D|rcsb pdb:3TW4|rcsb pdb:6N0B|rcsb pdb:6N12|rcsb pdb:6UQQ|reactome:R-HSA-5687128 omim:614822(see-also)|go:"GO:0099512"(supramolecular fiber) crc64:12CCBBE30806F92F - figure legend:4F|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-nt2d1)|taxid:9606("human NTERA-2 d.D1 (NT2D1) testicular embryonal carcinoma cell line") - 2016/11/16 2017/01/17 rogid:H0Us8GtPe2XuXlOYXC0DX79kB/49606 rogid:CweIjGLXC7eubvKR7vkkihEkcHg9606 rigid:f+fHwMdjRNrn265IovXHjdlp26s false - flag tag:n-n - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q8IYM1 uniprotkb:Q16181 intact:EBI-2585067|uniprotkb:Q96LL0|uniprotkb:Q0P6B0|uniprotkb:Q1PBH0|ensembl:ENSP00000268231 intact:EBI-2009373|uniprotkb:Q52M76|uniprotkb:Q6NX50|ensembl:ENSP00000381992 psi-mi:sep12_human(display_long)|uniprotkb:SEPTIN12(gene name)|psi-mi:SEPTIN12(display_short)|uniprotkb:SEPT12(gene name synonym) psi-mi:sept7_human(display_long)|uniprotkb:SEPTIN7(gene name)|psi-mi:SEPTIN7(display_short)|uniprotkb:CDC10(gene name synonym)|uniprotkb:CDC10 protein homolog(gene name synonym)|uniprotkb:SEPT7(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2015) pubmed:25588830|imex:IM-25619 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-12598534|imex:IM-25619-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001147930.1|refseq:NP_653206.2|refseq:XP_006720909.1|ensembl:ENSG00000140623(gene)|ensembl:ENST00000268231(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097227"(sperm annulus)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:6MQ9|rcsb pdb:6MQB|rcsb pdb:6MQK|rcsb pdb:6MQL refseq:NP_001779.3|dip:DIP-47093N|ensembl:ENSG00000122545(gene)|ensembl:ENST00000399034(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016476"(regulation of embryonic cell shape)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097227"(sperm annulus)|go:"GO:0097730"(non-motile cilium)|go:"GO:1902857"(positive regulation of non-motile cilium assembly)|interpro:IPR008115(Septin 7)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:2QAG|rcsb pdb:3T5D|rcsb pdb:3TW4|rcsb pdb:6N0B|rcsb pdb:6N12|rcsb pdb:6UQQ|reactome:R-HSA-5687128 omim:614822(see-also) - - figure legend:"3A (lane 1), supplementary S4"|comment:Without SEPT7 overexpression, the interactions between SEPT12 and SEPT2 as well as SEPT6 were dramatically reduced.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/11/16 2016/11/16 rogid:JVg1xMDlUm2RuG5VukrGDWI/Rz09606 rogid:CweIjGLXC7eubvKR7vkkihEkcHg9606 rigid:n1KcggPw+D6XHOstI1iAKEwLJ6E false green fluorescent protein tag:c-c|mutation disrupting interaction strength:89-89|mutation disrupting interaction strength:197-197 flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8IYM1 uniprotkb:Q14141 intact:EBI-2585067|uniprotkb:Q96LL0|uniprotkb:Q0P6B0|uniprotkb:Q1PBH0|ensembl:ENSP00000268231 intact:EBI-745901|uniprotkb:Q5JTK0|uniprotkb:Q969W5|uniprotkb:Q96A13|uniprotkb:Q96GR1|uniprotkb:Q96P86|uniprotkb:Q96P87|intact:EBI-1047521|ensembl:ENSP00000341524 psi-mi:sep12_human(display_long)|uniprotkb:SEPTIN12(gene name)|psi-mi:SEPTIN12(display_short)|uniprotkb:SEPT12(gene name synonym) psi-mi:sept6_human(display_long)|uniprotkb:SEPTIN6(gene name)|psi-mi:SEPTIN6(display_short)|uniprotkb:KIAA0128(gene name synonym)|uniprotkb:SEP2(gene name synonym)|uniprotkb:SEPT6(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2015) pubmed:25588830|imex:IM-25619 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-12598534|imex:IM-25619-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001147930.1|refseq:NP_653206.2|refseq:XP_006720909.1|ensembl:ENSG00000140623(gene)|ensembl:ENST00000268231(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097227"(sperm annulus)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:6MQ9|rcsb pdb:6MQB|rcsb pdb:6MQK|rcsb pdb:6MQL ensembl:ENSG00000125354(gene)|ensembl:ENST00000343984(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000776"(kinetochore)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005819"(spindle)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032173"(septin collar)|go:"GO:0034613"(cellular protein localization)|go:"GO:0043679"(axon terminus)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097227"(sperm annulus)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|interpro:IPR030644|mint:Q14141|rcsb pdb:2QAG|rcsb pdb:6UPA|rcsb pdb:6WBP|refseq:NP_055944.2|refseq:NP_665798.1|refseq:NP_665799.1|refseq:NP_665801.1|refseq:XP_006724813.1|dip:DIP-38218N omim:614822(see-also) - - figure legend:"3A (lane 1), supplementary S4"|comment:Without SEPT7 overexpression, the interactions between SEPT12 and SEPT2 as well as SEPT6 were dramatically reduced.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/11/16 2016/11/16 rogid:JVg1xMDlUm2RuG5VukrGDWI/Rz09606 rogid:gH1JHXyE/7o3I8i4ZS3bMoF7zvU9606 rigid:n1KcggPw+D6XHOstI1iAKEwLJ6E false green fluorescent protein tag:c-c|mutation disrupting interaction strength:89-89|mutation disrupting interaction strength:197-197 myc tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8IYM1 uniprotkb:Q15019 intact:EBI-2585067|uniprotkb:Q96LL0|uniprotkb:Q0P6B0|uniprotkb:Q1PBH0|ensembl:ENSP00000268231 intact:EBI-741220|intact:EBI-28986019|ensembl:ENSP00000353157|ensembl:ENSP00000375832|ensembl:ENSP00000375834|ensembl:ENSP00000385172|uniprotkb:Q14132|uniprotkb:Q8IUK9|uniprotkb:Q96CB0|uniprotkb:B4DGE8|uniprotkb:Q53QU3 psi-mi:sep12_human(display_long)|uniprotkb:SEPTIN12(gene name)|psi-mi:SEPTIN12(display_short)|uniprotkb:SEPT12(gene name synonym) psi-mi:sept2_human(display_long)|uniprotkb:SEPTIN2(gene name)|psi-mi:SEPTIN2(display_short)|uniprotkb:DIFF6(gene name synonym)|uniprotkb:KIAA0158(gene name synonym)|uniprotkb:NEDD5(gene name synonym)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 5(gene name synonym)|uniprotkb:SEPT2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2015) pubmed:25588830|imex:IM-25619 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-12598534|imex:IM-25619-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001147930.1|refseq:NP_653206.2|refseq:XP_006720909.1|ensembl:ENSG00000140623(gene)|ensembl:ENST00000268231(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097227"(sperm annulus)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:6MQ9|rcsb pdb:6MQB|rcsb pdb:6MQK|rcsb pdb:6MQL refseq:NP_001269901.1|refseq:NP_001269902.1|ensembl:ENSG00000168385(gene)|ensembl:ENST00000360051(transcript)|ensembl:ENST00000391971(transcript)|ensembl:ENST00000391973(transcript)|ensembl:ENST00000402092(transcript)|go:"GO:0000145"(exocyst)|go:"GO:0000776"(kinetochore)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005886"(plasma membrane)|go:"GO:0005930"(axoneme)|go:"GO:0005940"(septin ring)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042802"(identical protein binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045296"(cadherin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097227"(sperm annulus)|go:"GO:0097730"(non-motile cilium)|interpro:IPR008113(Septin 2)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|mint:Q15019|rcsb pdb:2QA5|rcsb pdb:2QAG|rcsb pdb:2QNR|rcsb pdb:6UPA|rcsb pdb:6UPQ|rcsb pdb:6UPR|reactome:R-HSA-5620912|refseq:NP_001008491.1|refseq:NP_001008492.1|refseq:NP_004395.1|refseq:NP_006146.1|refseq:XP_016859694.1|refseq:XP_016859695.1|refseq:NP_001307958.1|refseq:NP_001307959.1|refseq:NP_001307960.1|refseq:NP_001307961.1|refseq:NP_001307962.1|refseq:NP_001307963.1|refseq:NP_001307964.1|ensembl:ENSP00000353157|ensembl:ENSP00000375832|ensembl:ENSP00000375834|ensembl:ENST00000401990|ensembl:ENSP00000385109|ensembl:ENSP00000385172|ensembl:ENST00000616972|ensembl:ENSP00000479861|dip:DIP-38220N omim:614822(see-also) - crc64:12CCBBE30806F92F figure legend:"3A (lane 1), supplementary S4"|comment:Without SEPT7 overexpression, the interactions between SEPT12 and SEPT2 as well as SEPT6 were dramatically reduced.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/11/16 2016/11/16 rogid:JVg1xMDlUm2RuG5VukrGDWI/Rz09606 rogid:H0Us8GtPe2XuXlOYXC0DX79kB/49606 rigid:n1KcggPw+D6XHOstI1iAKEwLJ6E false green fluorescent protein tag:c-c|mutation disrupting interaction strength:89-89|mutation disrupting interaction strength:197-197 ha tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8IYM1 uniprotkb:O43236 intact:EBI-2585067|uniprotkb:Q96LL0|uniprotkb:Q0P6B0|uniprotkb:Q1PBH0|ensembl:ENSP00000268231 intact:EBI-1047513|uniprotkb:Q9UM58|uniprotkb:Q6IAP3|uniprotkb:B2RD42|uniprotkb:B3KSX9|uniprotkb:B4DXC6|uniprotkb:B4DXV5|uniprotkb:Q9H315|ensembl:ENSP00000321674|uniprotkb:A0A5F9ZHH3|uniprotkb:Q8N821|uniprotkb:Q8NEP4|intact:EBI-25939820|intact:EBI-13336111 psi-mi:sep12_human(display_long)|uniprotkb:SEPTIN12(gene name)|psi-mi:SEPTIN12(display_short)|uniprotkb:SEPT12(gene name synonym) psi-mi:sept4_human(display_long)|uniprotkb:SEPTIN4(gene name)|psi-mi:SEPTIN4(display_short)|uniprotkb:ARTS(gene name synonym)|uniprotkb:Apoptosis-related protein in the TGF-beta signaling pathway(gene name synonym)|uniprotkb:Bradeion beta(gene name synonym)|uniprotkb:Brain protein H5(gene name synonym)|uniprotkb:CE5B3 beta(gene name synonym)|uniprotkb:Cell division control-related protein 2(gene name synonym)|uniprotkb:Cerebral protein 7(gene name synonym)|uniprotkb:PNUTL2(gene name synonym)|uniprotkb:Peanut-like protein 2(gene name synonym)|uniprotkb:SEP4(gene name synonym)|uniprotkb:SEPT4(gene name synonym)|uniprotkb:hucep-7(orf name)|uniprotkb:C17orf47(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2015) pubmed:25588830|imex:IM-25619 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-12598606|imex:IM-25619-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001147930.1|refseq:NP_653206.2|refseq:XP_006720909.1|ensembl:ENSG00000140623(gene)|ensembl:ENST00000268231(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097227"(sperm annulus)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:6MQ9|rcsb pdb:6MQB|rcsb pdb:6MQK|rcsb pdb:6MQL refseq:XP_011523213.1|refseq:XP_011523214.1|refseq:NP_001185642.1|refseq:NP_004565.1|refseq:NP_536341.1|refseq:NP_536340.1|refseq:NP_001033793.2|refseq:NP_001243711.1|refseq:NP_001243751.1|ensembl:ENSG00000108387(gene)|interpro:IPR027417|interpro:IPR030379|mint:O43236|rcsb pdb:6WB3|reactome:R-HSA-111457|reactome:R-HSA-111469|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|ensembl:ENST00000317268(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005940"(septin ring)|go:"GO:0006915"(apoptotic process)|go:"GO:0001764"(neuron migration)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0003924"(GTPase activity)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0005198"(structural molecule activity)|go:"GO:0031105"(septin complex)|go:"GO:0005525"(GTP binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0032153"(cell division site)|go:"GO:0034613"(cellular protein localization)|go:"GO:0005654"(nucleoplasm)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043204"(perikaryon)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097227"(sperm annulus)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR016491(Septin)|refseq:XP_006722017.1|refseq:XP_006722018.1 - - - figure legend:"3B (lane 1)"|comment:Without SEPT7 overexpression, the interactions between SEPT12 and SEPT4 as well as SEPT6 were dramatically reduced.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/11/16 2016/11/16 rogid:JVg1xMDlUm2RuG5VukrGDWI/Rz09606 rogid:bS5LZDK5bxr0WEZsE35enupzNQs9606 rigid:Dn4RZU8OOPGXMoZTfDU8bQRLEf4 false flag tag:n-n ha tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8IYM1 uniprotkb:Q16181 intact:EBI-2585067|uniprotkb:Q96LL0|uniprotkb:Q0P6B0|uniprotkb:Q1PBH0|ensembl:ENSP00000268231 intact:EBI-2009373|uniprotkb:Q52M76|uniprotkb:Q6NX50|ensembl:ENSP00000381992 psi-mi:sep12_human(display_long)|uniprotkb:SEPTIN12(gene name)|psi-mi:SEPTIN12(display_short)|uniprotkb:SEPT12(gene name synonym) psi-mi:sept7_human(display_long)|uniprotkb:SEPTIN7(gene name)|psi-mi:SEPTIN7(display_short)|uniprotkb:CDC10(gene name synonym)|uniprotkb:CDC10 protein homolog(gene name synonym)|uniprotkb:SEPT7(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2015) pubmed:25588830|imex:IM-25619 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-12598606|imex:IM-25619-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001147930.1|refseq:NP_653206.2|refseq:XP_006720909.1|ensembl:ENSG00000140623(gene)|ensembl:ENST00000268231(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097227"(sperm annulus)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:6MQ9|rcsb pdb:6MQB|rcsb pdb:6MQK|rcsb pdb:6MQL refseq:NP_001779.3|dip:DIP-47093N|ensembl:ENSG00000122545(gene)|ensembl:ENST00000399034(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016476"(regulation of embryonic cell shape)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097227"(sperm annulus)|go:"GO:0097730"(non-motile cilium)|go:"GO:1902857"(positive regulation of non-motile cilium assembly)|interpro:IPR008115(Septin 7)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:2QAG|rcsb pdb:3T5D|rcsb pdb:3TW4|rcsb pdb:6N0B|rcsb pdb:6N12|rcsb pdb:6UQQ|reactome:R-HSA-5687128 - - - figure legend:"3B (lane 1)"|comment:Without SEPT7 overexpression, the interactions between SEPT12 and SEPT4 as well as SEPT6 were dramatically reduced.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/11/16 2016/11/16 rogid:JVg1xMDlUm2RuG5VukrGDWI/Rz09606 rogid:CweIjGLXC7eubvKR7vkkihEkcHg9606 rigid:Dn4RZU8OOPGXMoZTfDU8bQRLEf4 false flag tag:n-n green fluorescent protein tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8IYM1 uniprotkb:Q14141 intact:EBI-2585067|uniprotkb:Q96LL0|uniprotkb:Q0P6B0|uniprotkb:Q1PBH0|ensembl:ENSP00000268231 intact:EBI-745901|uniprotkb:Q5JTK0|uniprotkb:Q969W5|uniprotkb:Q96A13|uniprotkb:Q96GR1|uniprotkb:Q96P86|uniprotkb:Q96P87|intact:EBI-1047521|ensembl:ENSP00000341524 psi-mi:sep12_human(display_long)|uniprotkb:SEPTIN12(gene name)|psi-mi:SEPTIN12(display_short)|uniprotkb:SEPT12(gene name synonym) psi-mi:sept6_human(display_long)|uniprotkb:SEPTIN6(gene name)|psi-mi:SEPTIN6(display_short)|uniprotkb:KIAA0128(gene name synonym)|uniprotkb:SEP2(gene name synonym)|uniprotkb:SEPT6(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2015) pubmed:25588830|imex:IM-25619 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-12598606|imex:IM-25619-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001147930.1|refseq:NP_653206.2|refseq:XP_006720909.1|ensembl:ENSG00000140623(gene)|ensembl:ENST00000268231(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097227"(sperm annulus)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:6MQ9|rcsb pdb:6MQB|rcsb pdb:6MQK|rcsb pdb:6MQL ensembl:ENSG00000125354(gene)|ensembl:ENST00000343984(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000776"(kinetochore)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005819"(spindle)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032173"(septin collar)|go:"GO:0034613"(cellular protein localization)|go:"GO:0043679"(axon terminus)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097227"(sperm annulus)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|interpro:IPR030644|mint:Q14141|rcsb pdb:2QAG|rcsb pdb:6UPA|rcsb pdb:6WBP|refseq:NP_055944.2|refseq:NP_665798.1|refseq:NP_665799.1|refseq:NP_665801.1|refseq:XP_006724813.1|dip:DIP-38218N - - - figure legend:"3B (lane 1)"|comment:Without SEPT7 overexpression, the interactions between SEPT12 and SEPT4 as well as SEPT6 were dramatically reduced.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/11/16 2016/11/16 rogid:JVg1xMDlUm2RuG5VukrGDWI/Rz09606 rogid:gH1JHXyE/7o3I8i4ZS3bMoF7zvU9606 rigid:Dn4RZU8OOPGXMoZTfDU8bQRLEf4 false flag tag:n-n myc tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8IYM1 uniprotkb:Q16181 intact:EBI-2585067|uniprotkb:Q96LL0|uniprotkb:Q0P6B0|uniprotkb:Q1PBH0|ensembl:ENSP00000268231 intact:EBI-2009373|uniprotkb:Q52M76|uniprotkb:Q6NX50|ensembl:ENSP00000381992 psi-mi:sep12_human(display_long)|uniprotkb:SEPTIN12(gene name)|psi-mi:SEPTIN12(display_short)|uniprotkb:SEPT12(gene name synonym) psi-mi:sept7_human(display_long)|uniprotkb:SEPTIN7(gene name)|psi-mi:SEPTIN7(display_short)|uniprotkb:CDC10(gene name synonym)|uniprotkb:CDC10 protein homolog(gene name synonym)|uniprotkb:SEPT7(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2015) pubmed:25588830|imex:IM-25619 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-12732006|imex:IM-25619-32 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001147930.1|refseq:NP_653206.2|refseq:XP_006720909.1|ensembl:ENSG00000140623(gene)|ensembl:ENST00000268231(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097227"(sperm annulus)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:6MQ9|rcsb pdb:6MQB|rcsb pdb:6MQK|rcsb pdb:6MQL refseq:NP_001779.3|dip:DIP-47093N|ensembl:ENSG00000122545(gene)|ensembl:ENST00000399034(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016476"(regulation of embryonic cell shape)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097227"(sperm annulus)|go:"GO:0097730"(non-motile cilium)|go:"GO:1902857"(positive regulation of non-motile cilium assembly)|interpro:IPR008115(Septin 7)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:2QAG|rcsb pdb:3T5D|rcsb pdb:3TW4|rcsb pdb:6N0B|rcsb pdb:6N12|rcsb pdb:6UQQ|reactome:R-HSA-5687128 omim:614822(see-also) - - figure legend:"3A (lane 2)"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/11/16 2016/12/20 rogid:JVg1xMDlUm2RuG5VukrGDWI/Rz09606 rogid:CweIjGLXC7eubvKR7vkkihEkcHg9606 rigid:pVfK2ykfznI4+zALrpbdlPCKuCw false green fluorescent protein tag:c-c|mutation disrupting interaction strength:89-89|mutation disrupting interaction strength:197-197 flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8IYM1 uniprotkb:Q14141 intact:EBI-2585067|uniprotkb:Q96LL0|uniprotkb:Q0P6B0|uniprotkb:Q1PBH0|ensembl:ENSP00000268231 intact:EBI-745901|uniprotkb:Q5JTK0|uniprotkb:Q969W5|uniprotkb:Q96A13|uniprotkb:Q96GR1|uniprotkb:Q96P86|uniprotkb:Q96P87|intact:EBI-1047521|ensembl:ENSP00000341524 psi-mi:sep12_human(display_long)|uniprotkb:SEPTIN12(gene name)|psi-mi:SEPTIN12(display_short)|uniprotkb:SEPT12(gene name synonym) psi-mi:sept6_human(display_long)|uniprotkb:SEPTIN6(gene name)|psi-mi:SEPTIN6(display_short)|uniprotkb:KIAA0128(gene name synonym)|uniprotkb:SEP2(gene name synonym)|uniprotkb:SEPT6(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2015) pubmed:25588830|imex:IM-25619 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-12732006|imex:IM-25619-32 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001147930.1|refseq:NP_653206.2|refseq:XP_006720909.1|ensembl:ENSG00000140623(gene)|ensembl:ENST00000268231(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097227"(sperm annulus)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:6MQ9|rcsb pdb:6MQB|rcsb pdb:6MQK|rcsb pdb:6MQL ensembl:ENSG00000125354(gene)|ensembl:ENST00000343984(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000776"(kinetochore)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005819"(spindle)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032173"(septin collar)|go:"GO:0034613"(cellular protein localization)|go:"GO:0043679"(axon terminus)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097227"(sperm annulus)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|interpro:IPR030644|mint:Q14141|rcsb pdb:2QAG|rcsb pdb:6UPA|rcsb pdb:6WBP|refseq:NP_055944.2|refseq:NP_665798.1|refseq:NP_665799.1|refseq:NP_665801.1|refseq:XP_006724813.1|dip:DIP-38218N omim:614822(see-also) - - figure legend:"3A (lane 2)"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/11/16 2016/12/20 rogid:JVg1xMDlUm2RuG5VukrGDWI/Rz09606 rogid:gH1JHXyE/7o3I8i4ZS3bMoF7zvU9606 rigid:pVfK2ykfznI4+zALrpbdlPCKuCw false green fluorescent protein tag:c-c|mutation disrupting interaction strength:89-89|mutation disrupting interaction strength:197-197 myc tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q16181 uniprotkb:Q8IYM1 intact:EBI-2009373|uniprotkb:Q52M76|uniprotkb:Q6NX50|ensembl:ENSP00000381992 intact:EBI-2585067|uniprotkb:Q96LL0|uniprotkb:Q0P6B0|uniprotkb:Q1PBH0|ensembl:ENSP00000268231 psi-mi:sept7_human(display_long)|uniprotkb:SEPTIN7(gene name)|psi-mi:SEPTIN7(display_short)|uniprotkb:CDC10(gene name synonym)|uniprotkb:CDC10 protein homolog(gene name synonym)|uniprotkb:SEPT7(gene name synonym) psi-mi:sep12_human(display_long)|uniprotkb:SEPTIN12(gene name)|psi-mi:SEPTIN12(display_short)|uniprotkb:SEPT12(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2015) pubmed:25588830|imex:IM-25619 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-12732027|imex:IM-25619-33 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001779.3|dip:DIP-47093N|ensembl:ENSG00000122545(gene)|ensembl:ENST00000399034(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016476"(regulation of embryonic cell shape)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097227"(sperm annulus)|go:"GO:0097730"(non-motile cilium)|go:"GO:1902857"(positive regulation of non-motile cilium assembly)|interpro:IPR008115(Septin 7)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:2QAG|rcsb pdb:3T5D|rcsb pdb:3TW4|rcsb pdb:6N0B|rcsb pdb:6N12|rcsb pdb:6UQQ|reactome:R-HSA-5687128 refseq:NP_001147930.1|refseq:NP_653206.2|refseq:XP_006720909.1|ensembl:ENSG00000140623(gene)|ensembl:ENST00000268231(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097227"(sperm annulus)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:6MQ9|rcsb pdb:6MQB|rcsb pdb:6MQK|rcsb pdb:6MQL - - - figure legend:"3A (lane 3)"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/11/16 2016/12/20 rogid:CweIjGLXC7eubvKR7vkkihEkcHg9606 rogid:JVg1xMDlUm2RuG5VukrGDWI/Rz09606 rigid:hDfziRCIGAQdBG6Yaq7Pa2Z74Ac false flag tag:n-n green fluorescent protein tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q16181 uniprotkb:Q8IYM1 intact:EBI-2009373|uniprotkb:Q52M76|uniprotkb:Q6NX50|ensembl:ENSP00000381992 intact:EBI-2585067|uniprotkb:Q96LL0|uniprotkb:Q0P6B0|uniprotkb:Q1PBH0|ensembl:ENSP00000268231 psi-mi:sept7_human(display_long)|uniprotkb:SEPTIN7(gene name)|psi-mi:SEPTIN7(display_short)|uniprotkb:CDC10(gene name synonym)|uniprotkb:CDC10 protein homolog(gene name synonym)|uniprotkb:SEPT7(gene name synonym) psi-mi:sep12_human(display_long)|uniprotkb:SEPTIN12(gene name)|psi-mi:SEPTIN12(display_short)|uniprotkb:SEPT12(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2015) pubmed:25588830|imex:IM-25619 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-12732040|imex:IM-25619-34 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001779.3|dip:DIP-47093N|ensembl:ENSG00000122545(gene)|ensembl:ENST00000399034(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016476"(regulation of embryonic cell shape)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097227"(sperm annulus)|go:"GO:0097730"(non-motile cilium)|go:"GO:1902857"(positive regulation of non-motile cilium assembly)|interpro:IPR008115(Septin 7)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:2QAG|rcsb pdb:3T5D|rcsb pdb:3TW4|rcsb pdb:6N0B|rcsb pdb:6N12|rcsb pdb:6UQQ|reactome:R-HSA-5687128 refseq:NP_001147930.1|refseq:NP_653206.2|refseq:XP_006720909.1|ensembl:ENSG00000140623(gene)|ensembl:ENST00000268231(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097227"(sperm annulus)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:6MQ9|rcsb pdb:6MQB|rcsb pdb:6MQK|rcsb pdb:6MQL - - - figure legend:"3B (lane 3)"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/11/16 2016/12/20 rogid:CweIjGLXC7eubvKR7vkkihEkcHg9606 rogid:JVg1xMDlUm2RuG5VukrGDWI/Rz09606 rigid:hDfziRCIGAQdBG6Yaq7Pa2Z74Ac false green fluorescent protein tag:?-? flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8IYM1 uniprotkb:Q16181 intact:EBI-2585067|uniprotkb:Q96LL0|uniprotkb:Q0P6B0|uniprotkb:Q1PBH0|ensembl:ENSP00000268231 intact:EBI-2009373|uniprotkb:Q52M76|uniprotkb:Q6NX50|ensembl:ENSP00000381992 psi-mi:sep12_human(display_long)|uniprotkb:SEPTIN12(gene name)|psi-mi:SEPTIN12(display_short)|uniprotkb:SEPT12(gene name synonym) psi-mi:sept7_human(display_long)|uniprotkb:SEPTIN7(gene name)|psi-mi:SEPTIN7(display_short)|uniprotkb:CDC10(gene name synonym)|uniprotkb:CDC10 protein homolog(gene name synonym)|uniprotkb:SEPT7(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2015) pubmed:25588830|imex:IM-25619 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-12734308|imex:IM-25619-35 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001147930.1|refseq:NP_653206.2|refseq:XP_006720909.1|ensembl:ENSG00000140623(gene)|ensembl:ENST00000268231(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097227"(sperm annulus)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:6MQ9|rcsb pdb:6MQB|rcsb pdb:6MQK|rcsb pdb:6MQL refseq:NP_001779.3|dip:DIP-47093N|ensembl:ENSG00000122545(gene)|ensembl:ENST00000399034(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016476"(regulation of embryonic cell shape)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097227"(sperm annulus)|go:"GO:0097730"(non-motile cilium)|go:"GO:1902857"(positive regulation of non-motile cilium assembly)|interpro:IPR008115(Septin 7)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:2QAG|rcsb pdb:3T5D|rcsb pdb:3TW4|rcsb pdb:6N0B|rcsb pdb:6N12|rcsb pdb:6UQQ|reactome:R-HSA-5687128 - - - figure legend:"3B (lane 2)"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/11/16 2016/12/21 rogid:JVg1xMDlUm2RuG5VukrGDWI/Rz09606 rogid:CweIjGLXC7eubvKR7vkkihEkcHg9606 rigid:pVfK2ykfznI4+zALrpbdlPCKuCw false flag tag:n-n green fluorescent protein tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8IYM1 uniprotkb:Q14141 intact:EBI-2585067|uniprotkb:Q96LL0|uniprotkb:Q0P6B0|uniprotkb:Q1PBH0|ensembl:ENSP00000268231 intact:EBI-745901|uniprotkb:Q5JTK0|uniprotkb:Q969W5|uniprotkb:Q96A13|uniprotkb:Q96GR1|uniprotkb:Q96P86|uniprotkb:Q96P87|intact:EBI-1047521|ensembl:ENSP00000341524 psi-mi:sep12_human(display_long)|uniprotkb:SEPTIN12(gene name)|psi-mi:SEPTIN12(display_short)|uniprotkb:SEPT12(gene name synonym) psi-mi:sept6_human(display_long)|uniprotkb:SEPTIN6(gene name)|psi-mi:SEPTIN6(display_short)|uniprotkb:KIAA0128(gene name synonym)|uniprotkb:SEP2(gene name synonym)|uniprotkb:SEPT6(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kuo et al. (2015) pubmed:25588830|imex:IM-25619 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-12734308|imex:IM-25619-35 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001147930.1|refseq:NP_653206.2|refseq:XP_006720909.1|ensembl:ENSG00000140623(gene)|ensembl:ENST00000268231(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097227"(sperm annulus)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:6MQ9|rcsb pdb:6MQB|rcsb pdb:6MQK|rcsb pdb:6MQL ensembl:ENSG00000125354(gene)|ensembl:ENST00000343984(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000776"(kinetochore)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005819"(spindle)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032173"(septin collar)|go:"GO:0034613"(cellular protein localization)|go:"GO:0043679"(axon terminus)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097227"(sperm annulus)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|interpro:IPR030644|mint:Q14141|rcsb pdb:2QAG|rcsb pdb:6UPA|rcsb pdb:6WBP|refseq:NP_055944.2|refseq:NP_665798.1|refseq:NP_665799.1|refseq:NP_665801.1|refseq:XP_006724813.1|dip:DIP-38218N - - - figure legend:"3B (lane 2)"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/11/16 2016/12/21 rogid:JVg1xMDlUm2RuG5VukrGDWI/Rz09606 rogid:gH1JHXyE/7o3I8i4ZS3bMoF7zvU9606 rigid:pVfK2ykfznI4+zALrpbdlPCKuCw false flag tag:n-n myc tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:O55131 uniprotkb:Q9D451 intact:EBI-772161 intact:EBI-12688098|ensembl:ENSMUSP00000131062 psi-mi:sept7_mouse(display_long)|uniprotkb:Septin7(gene name)|psi-mi:Septin7(display_short)|uniprotkb:CDC10 protein homolog(gene name synonym)|uniprotkb:Cdc10(gene name synonym)|uniprotkb:Sept7(gene name synonym) psi-mi:q9d451_mouse(display_long)|uniprotkb:Septin12(gene name)|psi-mi:Septin12(display_short)|uniprotkb:Sept12(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Kuo et al. (2015) pubmed:25588830|imex:IM-25619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-12688117|imex:IM-25619-29 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001192296.1|interpro:IPR016491(Septin)|interpro:IPR008115(Septin 7)|interpro:IPR030379|interpro:IPR027417|mint:O55131|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000776"(kinetochore)|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005930"(axoneme)|go:"GO:0005938"(cell cortex)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016476"(regulation of embryonic cell shape)|go:"GO:0030496"(midbody)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0031105"(septin complex)|go:"GO:0031270"(pseudopodium retraction)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032160"(septin filament array)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043209"(myelin sheath)|go:"GO:0043679"(axon terminus)|go:"GO:0044297"(cell body)|go:"GO:0045202"(synapse)|go:"GO:0048668"(collateral sprouting)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097227"(sperm annulus)|go:"GO:0097730"(non-motile cilium)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099173"(postsynapse organization)|go:"GO:1902857"(positive regulation of non-motile cilium assembly)|reactome:R-MMU-5687128 refseq:NP_081945.1|refseq:NP_083650.1|ensembl:ENSMUSG00000022542(gene)|ensembl:ENSMUST00000170323(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005819"(spindle)|go:"GO:0005940"(septin ring)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097227"(sperm annulus)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|go:"GO:0032153"(cell division site)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060090"(molecular adaptor activity) go:"GO:0097227"(sperm annulus) - - figure legend:7B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-sperm)|taxid:10090(Mouse sperm) - 2016/11/16 2016/12/20 rogid:VULb4UyoWVn5vRWIzERa9YQJIYo10090 rogid:RjvSWkr6mCXIYgW5fZw7X15oQxI10090 rigid:fbFX5iPyrVDWxwN1g5xnNLZghIc false - mutation disrupting interaction:195-195 - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q9R1T4 uniprotkb:Q9D451 intact:EBI-772142|uniprotkb:A2A3V9|uniprotkb:A2A3W0|uniprotkb:Q3TRH9|uniprotkb:Q3TUA2|uniprotkb:Q542H3|uniprotkb:Q6A0C4|uniprotkb:Q8C2L2|uniprotkb:Q8C848|uniprotkb:Q91XH2|uniprotkb:Q9CZ94|ensembl:ENSMUSP00000110894 intact:EBI-12688098|ensembl:ENSMUSP00000131062 psi-mi:sept6_mouse(display_long)|uniprotkb:Septin6(gene name)|psi-mi:Septin6(display_short)|uniprotkb:Kiaa0128(gene name synonym)|uniprotkb:Sept6(gene name synonym) psi-mi:q9d451_mouse(display_long)|uniprotkb:Septin12(gene name)|psi-mi:Septin12(display_short)|uniprotkb:Sept12(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Kuo et al. (2015) pubmed:25588830|imex:IM-25619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-12688124|imex:IM-25619-30 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170794.1|refseq:NP_001170795.1|refseq:NP_064326.2|refseq:XP_006541452.1|refseq:XP_006541453.1|refseq:NP_001240635.1|ensembl:ENSMUSG00000050379(gene)|ensembl:ENSMUST00000115239(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005819"(spindle)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032173"(septin collar)|go:"GO:0034613"(cellular protein localization)|go:"GO:0043679"(axon terminus)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097227"(sperm annulus)|go:"GO:0098793"(presynapse)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|interpro:IPR030644|mint:Q9R1T4 refseq:NP_081945.1|refseq:NP_083650.1|ensembl:ENSMUSG00000022542(gene)|ensembl:ENSMUST00000170323(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005819"(spindle)|go:"GO:0005940"(septin ring)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097227"(sperm annulus)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|go:"GO:0032153"(cell division site)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060090"(molecular adaptor activity) go:"GO:0097227"(sperm annulus) - - figure legend:7B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-sperm)|taxid:10090(Mouse sperm) - 2016/11/16 2016/12/20 rogid:WX2NvMiU/872dG/1oc229JqIUEY10090 rogid:RjvSWkr6mCXIYgW5fZw7X15oQxI10090 rigid:41hxYUWPx52vl4Q3nLxyb5zUBdw false - mutation disrupting interaction:195-195 - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:P42208 uniprotkb:Q9D451 intact:EBI-772099|uniprotkb:Q3U9Y5|uniprotkb:B2RRZ2|ensembl:ENSMUSP00000027495|ensembl:ENSMUSP00000132850|ensembl:ENSMUSP00000136366 intact:EBI-12688098|ensembl:ENSMUSP00000131062 psi-mi:sept2_mouse(display_long)|uniprotkb:Sept2(gene name synonym)|uniprotkb:Septin2(gene name)|psi-mi:Septin2(display_short)|uniprotkb:Nedd5(gene name synonym)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 5(gene name synonym) psi-mi:q9d451_mouse(display_long)|uniprotkb:Septin12(gene name)|psi-mi:Septin12(display_short)|uniprotkb:Sept12(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Kuo et al. (2015) pubmed:25588830|imex:IM-25619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-12688131|imex:IM-25619-31 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001153189.1|refseq:NP_001153190.1|refseq:NP_001153191.1|refseq:NP_035021.1|refseq:XP_006529304.1|refseq:XP_006529305.1|dip:DIP-32438N|ensembl:ENSMUSG00000026276(gene)|ensembl:ENSMUSG00000116048(gene)|ensembl:ENSMUST00000027495(transcript)|ensembl:ENSMUST00000168776(transcript)|ensembl:ENSMUST00000179353(transcript)|go:"GO:0000145"(exocyst)|go:"GO:0000776"(kinetochore)|go:"GO:0002036"(regulation of L-glutamate import across plasma membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005826"(actomyosin contractile ring)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005930"(axoneme)|go:"GO:0005938"(cell cortex)|go:"GO:0005940"(septin ring)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0009986"(cell surface)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0043209"(myelin sheath)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051258"(protein polymerization)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097227"(sperm annulus)|go:"GO:0097730"(non-motile cilium)|interpro:IPR008113(Septin 2)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:3FTQ|reactome:R-MMU-5620912|mint:P42208 refseq:NP_081945.1|refseq:NP_083650.1|ensembl:ENSMUSG00000022542(gene)|ensembl:ENSMUST00000170323(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005819"(spindle)|go:"GO:0005940"(septin ring)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097227"(sperm annulus)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|go:"GO:0032153"(cell division site)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060090"(molecular adaptor activity) go:"GO:0097227"(sperm annulus) - - figure legend:7B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-sperm)|taxid:10090(Mouse sperm) - 2016/11/16 2016/12/20 rogid:vk7UVRzpfbNxL4cxXJhd94mfQxc10090 rogid:RjvSWkr6mCXIYgW5fZw7X15oQxI10090 rigid:st064DSM5glGmRoudqNQXJBGsqE false - mutation disrupting interaction:195-195 - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining)