#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P20459 uniprotkb:P09064 intact:EBI-8915|uniprotkb:E9P8T6|ensemblfungi:YJR007W|uniprotkb:D6VWI2 intact:EBI-8920|ensemblfungi:YPL237W|uniprotkb:Q6B200|uniprotkb:D6W3D3 psi-mi:if2a_yeast(display_long)|uniprotkb:SUI2(gene name)|psi-mi:SUI2(display_short)|uniprotkb:TIF211(gene name synonym)|uniprotkb:YJR007W(locus name)|uniprotkb:J1429(orf name) psi-mi:if2b_yeast(display_long)|uniprotkb:YPL237W(locus name)|uniprotkb:SUI3(gene name)|psi-mi:SUI3(display_short)|uniprotkb:TIF212(gene name synonym) psi-mi:"MI:0069"(mass spectrometry studies of complexes) Gordiyenko et al. (2013) pubmed:24852487|imex:IM-25313 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11711185|imex:IM-25313-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR022967|interpro:IPR024054|interpro:IPR024055|interpro:IPR044126|rcsb pdb:1Q46|rcsb pdb:2A19|rcsb pdb:2A1A|rcsb pdb:3J81|rcsb pdb:3JAP|rcsb pdb:3JAQ|rcsb pdb:6FYX|rcsb pdb:6FYY|rcsb pdb:6GSM|rcsb pdb:6GSN|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6JLY|rcsb pdb:6JLZ|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-156827|reactome:R-SCE-381042|reactome:R-SCE-72649|reactome:R-SCE-72695|reactome:R-SCE-72702|reactome:R-SCE-72731|ensemblfungi:YJR007W(gene)|ensemblfungi:YJR007W_mRNA(transcript)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005850"(eukaryotic translation initiation factor 2 complex)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0043022"(ribosome binding)|go:"GO:0043614"(multi-eIF complex)|interpro:IPR003029(S1, RNA binding)|interpro:IPR011488(Eukaryotic translation initiation factor 2, alpha subunit)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|refseq:NP_012540.3|sgd:S000003767|mint:P20459|dip:DIP-2327N ensemblfungi:YPL237W(gene)|ensemblfungi:YPL237W_mRNA(transcript)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005850"(eukaryotic translation initiation factor 2 complex)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0043614"(multi-eIF complex)|go:"GO:0046872"(metal ion binding)|interpro:IPR002735(Translation initiation factor IF2/IF5)|interpro:IPR016189(Translation initiation factor IF2/IF5, N-terminal)|interpro:IPR016190(Translation initiation factor IF2/IF5, zinc-binding)|rcsb pdb:3J81|rcsb pdb:3JAP|rcsb pdb:3JAQ|rcsb pdb:6FYX|rcsb pdb:6FYY|rcsb pdb:6GSM|rcsb pdb:6GSN|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72649|refseq:NP_015087.1|sgd:S000006158|reactome:R-SCE-156827|reactome:R-SCE-72695|reactome:R-SCE-72702|reactome:R-SCE-72731|dip:DIP-2310N|reactome:R-SCE-381042 - crc64:AF4F1C80303A4E98 crc64:34DE9323876CEE95 figure legend:Fig. 1A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2016/06/01 2016/06/14 rogid:9/iGImP9/c8HSYwgmItME27z7lE559292 rogid:64fjjpMNrNM6gZW2BzacUQWRC1I559292 rigid:qTPyHktlj1ToFFmcNf8R0+DycuI false - - 1 1 psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P20459 uniprotkb:P32481 intact:EBI-8915|uniprotkb:E9P8T6|ensemblfungi:YJR007W|uniprotkb:D6VWI2 intact:EBI-8924|ensemblfungi:YER025W|uniprotkb:D3DLS4 psi-mi:if2a_yeast(display_long)|uniprotkb:SUI2(gene name)|psi-mi:SUI2(display_short)|uniprotkb:TIF211(gene name synonym)|uniprotkb:YJR007W(locus name)|uniprotkb:J1429(orf name) psi-mi:if2g_yeast(display_long)|uniprotkb:YER025W(locus name)|uniprotkb:GCD11(gene name)|psi-mi:GCD11(display_short)|uniprotkb:TIF213(gene name synonym)|uniprotkb:SUI4(gene name synonym) psi-mi:"MI:0069"(mass spectrometry studies of complexes) Gordiyenko et al. (2013) pubmed:24852487|imex:IM-25313 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11711185|imex:IM-25313-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR022967|interpro:IPR024054|interpro:IPR024055|interpro:IPR044126|rcsb pdb:1Q46|rcsb pdb:2A19|rcsb pdb:2A1A|rcsb pdb:3J81|rcsb pdb:3JAP|rcsb pdb:3JAQ|rcsb pdb:6FYX|rcsb pdb:6FYY|rcsb pdb:6GSM|rcsb pdb:6GSN|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6JLY|rcsb pdb:6JLZ|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-156827|reactome:R-SCE-381042|reactome:R-SCE-72649|reactome:R-SCE-72695|reactome:R-SCE-72702|reactome:R-SCE-72731|ensemblfungi:YJR007W(gene)|ensemblfungi:YJR007W_mRNA(transcript)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005850"(eukaryotic translation initiation factor 2 complex)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0043022"(ribosome binding)|go:"GO:0043614"(multi-eIF complex)|interpro:IPR003029(S1, RNA binding)|interpro:IPR011488(Eukaryotic translation initiation factor 2, alpha subunit)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|refseq:NP_012540.3|sgd:S000003767|mint:P20459|dip:DIP-2327N rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-156827|reactome:R-SCE-381042|reactome:R-SCE-72649|reactome:R-SCE-72695|reactome:R-SCE-72702|reactome:R-SCE-72731|ensemblfungi:YER025W(gene)|ensemblfungi:YER025W_mRNA(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005850"(eukaryotic translation initiation factor 2 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0043614"(multi-eIF complex)|go:"GO:0045903"(positive regulation of translational fidelity)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR015256(Initiation factor eIF2 gamma, C terminal)|interpro:IPR027417|interpro:IPR044127|interpro:IPR044128|rcsb pdb:3J81|rcsb pdb:3JAP|rcsb pdb:3JAQ|rcsb pdb:4ZGN|rcsb pdb:4ZGQ|rcsb pdb:6FYX|rcsb pdb:6FYY|rcsb pdb:6GSM|rcsb pdb:6GSN|refseq:NP_010942.1|sgd:S000000827|mint:P32481|dip:DIP-2561N - crc64:AF4F1C80303A4E98 crc64:D498AE62BC3E81CD figure legend:Fig. 1A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2016/06/01 2016/06/14 rogid:9/iGImP9/c8HSYwgmItME27z7lE559292 rogid:KLaBewFsp1tygK0+hirsBIaMPEI559292 rigid:qTPyHktlj1ToFFmcNf8R0+DycuI false - his tag:c-c 1 1 psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P20459 uniprotkb:P32481 intact:EBI-8915|uniprotkb:E9P8T6|ensemblfungi:YJR007W|uniprotkb:D6VWI2 intact:EBI-8924|ensemblfungi:YER025W|uniprotkb:D3DLS4 psi-mi:if2a_yeast(display_long)|uniprotkb:SUI2(gene name)|psi-mi:SUI2(display_short)|uniprotkb:TIF211(gene name synonym)|uniprotkb:YJR007W(locus name)|uniprotkb:J1429(orf name) psi-mi:if2g_yeast(display_long)|uniprotkb:YER025W(locus name)|uniprotkb:GCD11(gene name)|psi-mi:GCD11(display_short)|uniprotkb:TIF213(gene name synonym)|uniprotkb:SUI4(gene name synonym) psi-mi:"MI:0069"(mass spectrometry studies of complexes) Gordiyenko et al. (2013) pubmed:24852487|imex:IM-25313 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11711192|imex:IM-25313-21 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR022967|interpro:IPR024054|interpro:IPR024055|interpro:IPR044126|rcsb pdb:1Q46|rcsb pdb:2A19|rcsb pdb:2A1A|rcsb pdb:3J81|rcsb pdb:3JAP|rcsb pdb:3JAQ|rcsb pdb:6FYX|rcsb pdb:6FYY|rcsb pdb:6GSM|rcsb pdb:6GSN|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6JLY|rcsb pdb:6JLZ|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-156827|reactome:R-SCE-381042|reactome:R-SCE-72649|reactome:R-SCE-72695|reactome:R-SCE-72702|reactome:R-SCE-72731|ensemblfungi:YJR007W(gene)|ensemblfungi:YJR007W_mRNA(transcript)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005850"(eukaryotic translation initiation factor 2 complex)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0043022"(ribosome binding)|go:"GO:0043614"(multi-eIF complex)|interpro:IPR003029(S1, RNA binding)|interpro:IPR011488(Eukaryotic translation initiation factor 2, alpha subunit)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|refseq:NP_012540.3|sgd:S000003767|mint:P20459|dip:DIP-2327N rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-156827|reactome:R-SCE-381042|reactome:R-SCE-72649|reactome:R-SCE-72695|reactome:R-SCE-72702|reactome:R-SCE-72731|ensemblfungi:YER025W(gene)|ensemblfungi:YER025W_mRNA(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005850"(eukaryotic translation initiation factor 2 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0043614"(multi-eIF complex)|go:"GO:0045903"(positive regulation of translational fidelity)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR015256(Initiation factor eIF2 gamma, C terminal)|interpro:IPR027417|interpro:IPR044127|interpro:IPR044128|rcsb pdb:3J81|rcsb pdb:3JAP|rcsb pdb:3JAQ|rcsb pdb:4ZGN|rcsb pdb:4ZGQ|rcsb pdb:6FYX|rcsb pdb:6FYY|rcsb pdb:6GSM|rcsb pdb:6GSN|refseq:NP_010942.1|sgd:S000000827|mint:P32481|dip:DIP-2561N - crc64:AF4F1C80303A4E98 crc64:D498AE62BC3E81CD figure legend:Fig. 1A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2016/06/01 2016/06/02 rogid:9/iGImP9/c8HSYwgmItME27z7lE559292 rogid:KLaBewFsp1tygK0+hirsBIaMPEI559292 rigid:0MSWuuRq1JwOXqX7MFNIobbhrX4 false - his tag:c-c 1 1 psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P14741 uniprotkb:P32502 intact:EBI-6253|uniprotkb:D6VX91|ensemblfungi:YKR026C intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C psi-mi:ei2ba_yeast(display_long)|uniprotkb:GCN3(gene name)|psi-mi:GCN3(display_short)|uniprotkb:AAS2(gene name synonym)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit alpha(gene name synonym)|uniprotkb:GCD complex subunit GCN3(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCN3(gene name synonym)|uniprotkb:TIF221(gene name synonym)|uniprotkb:YKR026C(locus name)|uniprotkb:Translational activator GCN3(gene name synonym) psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name) psi-mi:"MI:0069"(mass spectrometry studies of complexes) Gordiyenko et al. (2013) pubmed:24852487|imex:IM-25313 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11711204|imex:IM-25313-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012951.1|sgd:S000001734|dip:DIP-1328N|mint:P14741|ensemblfungi:YKR026C(gene)|ensemblfungi:YKR026C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|go:"GO:1903833"(positive regulation of cellular response to amino acid starvation)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR037171|interpro:IPR042528|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731 refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731 - crc64:8E9A928D6D56E12B crc64:A5409FAF1594854C figure legend:Fig. 1B, Supp. Fig. 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2016/06/01 2016/06/02 rogid:Nm+Ahop9EG8SQNZbo6+usIB9SAY559292 rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292 rigid:HjskxmufgC71B3axXvUyCtDNCGc false - - 2 2 psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P14741 uniprotkb:P12754 intact:EBI-6253|uniprotkb:D6VX91|ensemblfungi:YKR026C intact:EBI-6265|uniprotkb:D6VUL5|ensemblfungi:YGR083C psi-mi:ei2ba_yeast(display_long)|uniprotkb:GCN3(gene name)|psi-mi:GCN3(display_short)|uniprotkb:AAS2(gene name synonym)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit alpha(gene name synonym)|uniprotkb:GCD complex subunit GCN3(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCN3(gene name synonym)|uniprotkb:TIF221(gene name synonym)|uniprotkb:YKR026C(locus name)|uniprotkb:Translational activator GCN3(gene name synonym) psi-mi:ei2bd_yeast(display_long)|uniprotkb:GCD2(gene name)|psi-mi:GCD2(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit delta(gene name synonym)|uniprotkb:GCD complex subunit GCD2(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD2(gene name synonym)|uniprotkb:TIF224(gene name synonym)|uniprotkb:YGR083C(locus name) psi-mi:"MI:0069"(mass spectrometry studies of complexes) Gordiyenko et al. (2013) pubmed:24852487|imex:IM-25313 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11711204|imex:IM-25313-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012951.1|sgd:S000001734|dip:DIP-1328N|mint:P14741|ensemblfungi:YKR026C(gene)|ensemblfungi:YKR026C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|go:"GO:1903833"(positive regulation of cellular response to amino acid starvation)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR037171|interpro:IPR042528|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731 refseq:NP_011597.1|sgd:S000003315|dip:DIP-2343N|mint:P12754|ensemblfungi:YGR083C(gene)|ensemblfungi:YGR083C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR037171|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731 - crc64:8E9A928D6D56E12B crc64:B188457543CE1AAE figure legend:Fig. 1B, Supp. Fig. 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2016/06/01 2016/06/02 rogid:Nm+Ahop9EG8SQNZbo6+usIB9SAY559292 rogid:q04UNg7w1BfegEmJy01O+BDTJno559292 rigid:HjskxmufgC71B3axXvUyCtDNCGc false - - 2 2 psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P14741 uniprotkb:P32501 intact:EBI-6253|uniprotkb:D6VX91|ensemblfungi:YKR026C intact:EBI-6270|uniprotkb:D6VSJ5|ensemblfungi:YDR211W psi-mi:ei2ba_yeast(display_long)|uniprotkb:GCN3(gene name)|psi-mi:GCN3(display_short)|uniprotkb:AAS2(gene name synonym)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit alpha(gene name synonym)|uniprotkb:GCD complex subunit GCN3(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCN3(gene name synonym)|uniprotkb:TIF221(gene name synonym)|uniprotkb:YKR026C(locus name)|uniprotkb:Translational activator GCN3(gene name synonym) psi-mi:ei2be_yeast(display_long)|uniprotkb:GCD6(gene name)|psi-mi:GCD6(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit epsilon(gene name synonym)|uniprotkb:GCD complex subunit GCD6(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD6(gene name synonym)|uniprotkb:TIF225(gene name synonym)|uniprotkb:YD8142.12(orf name)|uniprotkb:YD8142B.03(orf name)|uniprotkb:YDR211W(locus name) psi-mi:"MI:0069"(mass spectrometry studies of complexes) Gordiyenko et al. (2013) pubmed:24852487|imex:IM-25313 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11711204|imex:IM-25313-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012951.1|sgd:S000001734|dip:DIP-1328N|mint:P14741|ensemblfungi:YKR026C(gene)|ensemblfungi:YKR026C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|go:"GO:1903833"(positive regulation of cellular response to amino acid starvation)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR037171|interpro:IPR042528|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731 sgd:S000002619|refseq:NP_010497.3|dip:DIP-2328N|mint:P32501|ensemblfungi:YDR211W(gene)|ensemblfungi:YDR211W_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR001451(Bacterial transferase hexapeptide repeat)|interpro:IPR003307(eIF4-gamma/eIF5/eIF2-epsilon)|interpro:IPR005835(Nucleotidyl transferase)|interpro:IPR011004(Trimeric LpxA-like)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR029044|interpro:IPR035543|interpro:IPR044123|rcsb pdb:1PAQ|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731 - crc64:8E9A928D6D56E12B crc64:EFE87F6AE2941619 figure legend:Fig. 1B, Supp. Fig. 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2016/06/01 2016/06/02 rogid:Nm+Ahop9EG8SQNZbo6+usIB9SAY559292 rogid:v70J4JmFrVbw38N8WqOg66aR634559292 rigid:HjskxmufgC71B3axXvUyCtDNCGc false - - 2 2 psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P14741 uniprotkb:P09032 intact:EBI-6253|uniprotkb:D6VX91|ensemblfungi:YKR026C intact:EBI-6275|uniprotkb:Q08721|uniprotkb:D6W2W1|ensemblfungi:YOR260W psi-mi:ei2ba_yeast(display_long)|uniprotkb:GCN3(gene name)|psi-mi:GCN3(display_short)|uniprotkb:AAS2(gene name synonym)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit alpha(gene name synonym)|uniprotkb:GCD complex subunit GCN3(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCN3(gene name synonym)|uniprotkb:TIF221(gene name synonym)|uniprotkb:YKR026C(locus name)|uniprotkb:Translational activator GCN3(gene name synonym) psi-mi:ei2bg_yeast(display_long)|uniprotkb:GCD1(gene name)|psi-mi:GCD1(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit gamma(gene name synonym)|uniprotkb:GCD complex subunit GCD1(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD1(gene name synonym)|uniprotkb:TIF223(gene name synonym)|uniprotkb:TRA3(gene name synonym)|uniprotkb:YOR260W(locus name) psi-mi:"MI:0069"(mass spectrometry studies of complexes) Gordiyenko et al. (2013) pubmed:24852487|imex:IM-25313 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11711204|imex:IM-25313-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012951.1|sgd:S000001734|dip:DIP-1328N|mint:P14741|ensemblfungi:YKR026C(gene)|ensemblfungi:YKR026C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|go:"GO:1903833"(positive regulation of cellular response to amino acid starvation)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR037171|interpro:IPR042528|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731 refseq:NP_014903.1|sgd:S000005786|dip:DIP-1327N|mint:P09032|ensemblfungi:YOR260W(gene)|ensemblfungi:YOR260W_mRNA(transcript)|go:"GO:0002183"(cytoplasmic translational initiation)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:1903574"(negative regulation of cellular response to amino acid starvation)|interpro:IPR011004(Trimeric LpxA-like)|interpro:IPR029044|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731 - crc64:8E9A928D6D56E12B crc64:EC25BAE00F4D1E94 figure legend:Fig. 1B, Supp. Fig. 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2016/06/01 2016/06/02 rogid:Nm+Ahop9EG8SQNZbo6+usIB9SAY559292 rogid:f7BMhuKpbYjQKxE4EmfcVgm6Zv4559292 rigid:HjskxmufgC71B3axXvUyCtDNCGc false - flag tag:c-c|his tag:c-c 2 2 psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P14741 uniprotkb:P32502 intact:EBI-6253|uniprotkb:D6VX91|ensemblfungi:YKR026C intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C psi-mi:ei2ba_yeast(display_long)|uniprotkb:GCN3(gene name)|psi-mi:GCN3(display_short)|uniprotkb:AAS2(gene name synonym)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit alpha(gene name synonym)|uniprotkb:GCD complex subunit GCN3(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCN3(gene name synonym)|uniprotkb:TIF221(gene name synonym)|uniprotkb:YKR026C(locus name)|uniprotkb:Translational activator GCN3(gene name synonym) psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name) psi-mi:"MI:0069"(mass spectrometry studies of complexes) Gordiyenko et al. (2013) pubmed:24852487|imex:IM-25313 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11711240|imex:IM-25313-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012951.1|sgd:S000001734|dip:DIP-1328N|mint:P14741|ensemblfungi:YKR026C(gene)|ensemblfungi:YKR026C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|go:"GO:1903833"(positive regulation of cellular response to amino acid starvation)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR037171|interpro:IPR042528|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731 refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731 - crc64:8E9A928D6D56E12B crc64:A5409FAF1594854C figure legend:Fig. 1B, Supp. Fig. 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2016/06/01 2016/06/02 rogid:Nm+Ahop9EG8SQNZbo6+usIB9SAY559292 rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292 rigid:HjskxmufgC71B3axXvUyCtDNCGc false - - 1 2 psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P14741 uniprotkb:P12754 intact:EBI-6253|uniprotkb:D6VX91|ensemblfungi:YKR026C intact:EBI-6265|uniprotkb:D6VUL5|ensemblfungi:YGR083C psi-mi:ei2ba_yeast(display_long)|uniprotkb:GCN3(gene name)|psi-mi:GCN3(display_short)|uniprotkb:AAS2(gene name synonym)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit alpha(gene name synonym)|uniprotkb:GCD complex subunit GCN3(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCN3(gene name synonym)|uniprotkb:TIF221(gene name synonym)|uniprotkb:YKR026C(locus name)|uniprotkb:Translational activator GCN3(gene name synonym) psi-mi:ei2bd_yeast(display_long)|uniprotkb:GCD2(gene name)|psi-mi:GCD2(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit delta(gene name synonym)|uniprotkb:GCD complex subunit GCD2(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD2(gene name synonym)|uniprotkb:TIF224(gene name synonym)|uniprotkb:YGR083C(locus name) psi-mi:"MI:0069"(mass spectrometry studies of complexes) Gordiyenko et al. (2013) pubmed:24852487|imex:IM-25313 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11711240|imex:IM-25313-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012951.1|sgd:S000001734|dip:DIP-1328N|mint:P14741|ensemblfungi:YKR026C(gene)|ensemblfungi:YKR026C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|go:"GO:1903833"(positive regulation of cellular response to amino acid starvation)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR037171|interpro:IPR042528|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731 refseq:NP_011597.1|sgd:S000003315|dip:DIP-2343N|mint:P12754|ensemblfungi:YGR083C(gene)|ensemblfungi:YGR083C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR037171|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731 - crc64:8E9A928D6D56E12B crc64:B188457543CE1AAE figure legend:Fig. 1B, Supp. Fig. 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2016/06/01 2016/06/02 rogid:Nm+Ahop9EG8SQNZbo6+usIB9SAY559292 rogid:q04UNg7w1BfegEmJy01O+BDTJno559292 rigid:HjskxmufgC71B3axXvUyCtDNCGc false - - 1 2 psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P14741 uniprotkb:P32501 intact:EBI-6253|uniprotkb:D6VX91|ensemblfungi:YKR026C intact:EBI-6270|uniprotkb:D6VSJ5|ensemblfungi:YDR211W psi-mi:ei2ba_yeast(display_long)|uniprotkb:GCN3(gene name)|psi-mi:GCN3(display_short)|uniprotkb:AAS2(gene name synonym)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit alpha(gene name synonym)|uniprotkb:GCD complex subunit GCN3(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCN3(gene name synonym)|uniprotkb:TIF221(gene name synonym)|uniprotkb:YKR026C(locus name)|uniprotkb:Translational activator GCN3(gene name synonym) psi-mi:ei2be_yeast(display_long)|uniprotkb:GCD6(gene name)|psi-mi:GCD6(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit epsilon(gene name synonym)|uniprotkb:GCD complex subunit GCD6(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD6(gene name synonym)|uniprotkb:TIF225(gene name synonym)|uniprotkb:YD8142.12(orf name)|uniprotkb:YD8142B.03(orf name)|uniprotkb:YDR211W(locus name) psi-mi:"MI:0069"(mass spectrometry studies of complexes) Gordiyenko et al. (2013) pubmed:24852487|imex:IM-25313 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11711240|imex:IM-25313-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012951.1|sgd:S000001734|dip:DIP-1328N|mint:P14741|ensemblfungi:YKR026C(gene)|ensemblfungi:YKR026C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|go:"GO:1903833"(positive regulation of cellular response to amino acid starvation)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR037171|interpro:IPR042528|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731 sgd:S000002619|refseq:NP_010497.3|dip:DIP-2328N|mint:P32501|ensemblfungi:YDR211W(gene)|ensemblfungi:YDR211W_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR001451(Bacterial transferase hexapeptide repeat)|interpro:IPR003307(eIF4-gamma/eIF5/eIF2-epsilon)|interpro:IPR005835(Nucleotidyl transferase)|interpro:IPR011004(Trimeric LpxA-like)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR029044|interpro:IPR035543|interpro:IPR044123|rcsb pdb:1PAQ|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731 - crc64:8E9A928D6D56E12B crc64:EFE87F6AE2941619 figure legend:Fig. 1B, Supp. Fig. 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2016/06/01 2016/06/02 rogid:Nm+Ahop9EG8SQNZbo6+usIB9SAY559292 rogid:v70J4JmFrVbw38N8WqOg66aR634559292 rigid:HjskxmufgC71B3axXvUyCtDNCGc false - - 1 2 psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P14741 uniprotkb:P09032 intact:EBI-6253|uniprotkb:D6VX91|ensemblfungi:YKR026C intact:EBI-6275|uniprotkb:Q08721|uniprotkb:D6W2W1|ensemblfungi:YOR260W psi-mi:ei2ba_yeast(display_long)|uniprotkb:GCN3(gene name)|psi-mi:GCN3(display_short)|uniprotkb:AAS2(gene name synonym)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit alpha(gene name synonym)|uniprotkb:GCD complex subunit GCN3(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCN3(gene name synonym)|uniprotkb:TIF221(gene name synonym)|uniprotkb:YKR026C(locus name)|uniprotkb:Translational activator GCN3(gene name synonym) psi-mi:ei2bg_yeast(display_long)|uniprotkb:GCD1(gene name)|psi-mi:GCD1(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit gamma(gene name synonym)|uniprotkb:GCD complex subunit GCD1(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD1(gene name synonym)|uniprotkb:TIF223(gene name synonym)|uniprotkb:TRA3(gene name synonym)|uniprotkb:YOR260W(locus name) psi-mi:"MI:0069"(mass spectrometry studies of complexes) Gordiyenko et al. (2013) pubmed:24852487|imex:IM-25313 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11711240|imex:IM-25313-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012951.1|sgd:S000001734|dip:DIP-1328N|mint:P14741|ensemblfungi:YKR026C(gene)|ensemblfungi:YKR026C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|go:"GO:1903833"(positive regulation of cellular response to amino acid starvation)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR037171|interpro:IPR042528|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731 refseq:NP_014903.1|sgd:S000005786|dip:DIP-1327N|mint:P09032|ensemblfungi:YOR260W(gene)|ensemblfungi:YOR260W_mRNA(transcript)|go:"GO:0002183"(cytoplasmic translational initiation)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:1903574"(negative regulation of cellular response to amino acid starvation)|interpro:IPR011004(Trimeric LpxA-like)|interpro:IPR029044|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731 - crc64:8E9A928D6D56E12B crc64:EC25BAE00F4D1E94 figure legend:Fig. 1B, Supp. Fig. 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2016/06/01 2016/06/02 rogid:Nm+Ahop9EG8SQNZbo6+usIB9SAY559292 rogid:f7BMhuKpbYjQKxE4EmfcVgm6Zv4559292 rigid:HjskxmufgC71B3axXvUyCtDNCGc false - flag tag:c-c|his tag:c-c 1 2 psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P32502 uniprotkb:P12754 intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C intact:EBI-6265|uniprotkb:D6VUL5|ensemblfungi:YGR083C psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name) psi-mi:ei2bd_yeast(display_long)|uniprotkb:GCD2(gene name)|psi-mi:GCD2(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit delta(gene name synonym)|uniprotkb:GCD complex subunit GCD2(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD2(gene name synonym)|uniprotkb:TIF224(gene name synonym)|uniprotkb:YGR083C(locus name) psi-mi:"MI:0069"(mass spectrometry studies of complexes) Gordiyenko et al. (2013) pubmed:24852487|imex:IM-25313 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11711251|imex:IM-25313-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731 refseq:NP_011597.1|sgd:S000003315|dip:DIP-2343N|mint:P12754|ensemblfungi:YGR083C(gene)|ensemblfungi:YGR083C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR037171|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731 - crc64:A5409FAF1594854C crc64:B188457543CE1AAE figure legend:Fig. 2A, 2B, Supp. Figs. 1 and 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2016/06/01 2016/06/02 rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292 rogid:q04UNg7w1BfegEmJy01O+BDTJno559292 rigid:u4htHhjsOBBGXifxTd1y+ZAR+PA false - - 2 2 psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P32502 uniprotkb:P32501 intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C intact:EBI-6270|uniprotkb:D6VSJ5|ensemblfungi:YDR211W psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name) psi-mi:ei2be_yeast(display_long)|uniprotkb:GCD6(gene name)|psi-mi:GCD6(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit epsilon(gene name synonym)|uniprotkb:GCD complex subunit GCD6(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD6(gene name synonym)|uniprotkb:TIF225(gene name synonym)|uniprotkb:YD8142.12(orf name)|uniprotkb:YD8142B.03(orf name)|uniprotkb:YDR211W(locus name) psi-mi:"MI:0069"(mass spectrometry studies of complexes) Gordiyenko et al. (2013) pubmed:24852487|imex:IM-25313 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11711251|imex:IM-25313-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731 sgd:S000002619|refseq:NP_010497.3|dip:DIP-2328N|mint:P32501|ensemblfungi:YDR211W(gene)|ensemblfungi:YDR211W_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR001451(Bacterial transferase hexapeptide repeat)|interpro:IPR003307(eIF4-gamma/eIF5/eIF2-epsilon)|interpro:IPR005835(Nucleotidyl transferase)|interpro:IPR011004(Trimeric LpxA-like)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR029044|interpro:IPR035543|interpro:IPR044123|rcsb pdb:1PAQ|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731 - crc64:A5409FAF1594854C crc64:EFE87F6AE2941619 figure legend:Fig. 2A, 2B, Supp. Figs. 1 and 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2016/06/01 2016/06/02 rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292 rogid:v70J4JmFrVbw38N8WqOg66aR634559292 rigid:u4htHhjsOBBGXifxTd1y+ZAR+PA false - - 2 2 psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P32502 uniprotkb:P09032 intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C intact:EBI-6275|uniprotkb:Q08721|uniprotkb:D6W2W1|ensemblfungi:YOR260W psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name) psi-mi:ei2bg_yeast(display_long)|uniprotkb:GCD1(gene name)|psi-mi:GCD1(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit gamma(gene name synonym)|uniprotkb:GCD complex subunit GCD1(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD1(gene name synonym)|uniprotkb:TIF223(gene name synonym)|uniprotkb:TRA3(gene name synonym)|uniprotkb:YOR260W(locus name) psi-mi:"MI:0069"(mass spectrometry studies of complexes) Gordiyenko et al. (2013) pubmed:24852487|imex:IM-25313 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11711251|imex:IM-25313-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731 refseq:NP_014903.1|sgd:S000005786|dip:DIP-1327N|mint:P09032|ensemblfungi:YOR260W(gene)|ensemblfungi:YOR260W_mRNA(transcript)|go:"GO:0002183"(cytoplasmic translational initiation)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:1903574"(negative regulation of cellular response to amino acid starvation)|interpro:IPR011004(Trimeric LpxA-like)|interpro:IPR029044|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731 - crc64:A5409FAF1594854C crc64:EC25BAE00F4D1E94 figure legend:Fig. 2A, 2B, Supp. Figs. 1 and 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2016/06/01 2016/06/02 rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292 rogid:f7BMhuKpbYjQKxE4EmfcVgm6Zv4559292 rigid:u4htHhjsOBBGXifxTd1y+ZAR+PA false - flag tag:c-c|his tag:c-c 2 2 psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P09032 uniprotkb:P32501 intact:EBI-6275|uniprotkb:Q08721|uniprotkb:D6W2W1|ensemblfungi:YOR260W intact:EBI-6270|uniprotkb:D6VSJ5|ensemblfungi:YDR211W psi-mi:ei2bg_yeast(display_long)|uniprotkb:GCD1(gene name)|psi-mi:GCD1(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit gamma(gene name synonym)|uniprotkb:GCD complex subunit GCD1(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD1(gene name synonym)|uniprotkb:TIF223(gene name synonym)|uniprotkb:TRA3(gene name synonym)|uniprotkb:YOR260W(locus name) psi-mi:ei2be_yeast(display_long)|uniprotkb:GCD6(gene name)|psi-mi:GCD6(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit epsilon(gene name synonym)|uniprotkb:GCD complex subunit GCD6(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD6(gene name synonym)|uniprotkb:TIF225(gene name synonym)|uniprotkb:YD8142.12(orf name)|uniprotkb:YD8142B.03(orf name)|uniprotkb:YDR211W(locus name) psi-mi:"MI:0069"(mass spectrometry studies of complexes) Gordiyenko et al. (2013) pubmed:24852487|imex:IM-25313 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11711261|imex:IM-25313-32 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014903.1|sgd:S000005786|dip:DIP-1327N|mint:P09032|ensemblfungi:YOR260W(gene)|ensemblfungi:YOR260W_mRNA(transcript)|go:"GO:0002183"(cytoplasmic translational initiation)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:1903574"(negative regulation of cellular response to amino acid starvation)|interpro:IPR011004(Trimeric LpxA-like)|interpro:IPR029044|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731 sgd:S000002619|refseq:NP_010497.3|dip:DIP-2328N|mint:P32501|ensemblfungi:YDR211W(gene)|ensemblfungi:YDR211W_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR001451(Bacterial transferase hexapeptide repeat)|interpro:IPR003307(eIF4-gamma/eIF5/eIF2-epsilon)|interpro:IPR005835(Nucleotidyl transferase)|interpro:IPR011004(Trimeric LpxA-like)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR029044|interpro:IPR035543|interpro:IPR044123|rcsb pdb:1PAQ|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731 - crc64:EC25BAE00F4D1E94 crc64:EFE87F6AE2941619 figure legend:Fig. 2 B/C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2016/06/01 2016/06/02 rogid:f7BMhuKpbYjQKxE4EmfcVgm6Zv4559292 rogid:v70J4JmFrVbw38N8WqOg66aR634559292 rigid:vJAgzcRddGZnbttTHaR/vUM/JGk false flag tag:c-c|his tag:c-c - 2 2 psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P32502 uniprotkb:P12754 intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C intact:EBI-6265|uniprotkb:D6VUL5|ensemblfungi:YGR083C psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name) psi-mi:ei2bd_yeast(display_long)|uniprotkb:GCD2(gene name)|psi-mi:GCD2(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit delta(gene name synonym)|uniprotkb:GCD complex subunit GCD2(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD2(gene name synonym)|uniprotkb:TIF224(gene name synonym)|uniprotkb:YGR083C(locus name) psi-mi:"MI:0069"(mass spectrometry studies of complexes) Gordiyenko et al. (2013) pubmed:24852487|imex:IM-25313 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11711270|imex:IM-25313-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731 refseq:NP_011597.1|sgd:S000003315|dip:DIP-2343N|mint:P12754|ensemblfungi:YGR083C(gene)|ensemblfungi:YGR083C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR037171|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731 - crc64:A5409FAF1594854C crc64:B188457543CE1AAE figure legend:Supp. Fig 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2016/06/01 2016/06/02 rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292 rogid:q04UNg7w1BfegEmJy01O+BDTJno559292 rigid:u4htHhjsOBBGXifxTd1y+ZAR+PA false - - 1 2 psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P32502 uniprotkb:P32501 intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C intact:EBI-6270|uniprotkb:D6VSJ5|ensemblfungi:YDR211W psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name) psi-mi:ei2be_yeast(display_long)|uniprotkb:GCD6(gene name)|psi-mi:GCD6(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit epsilon(gene name synonym)|uniprotkb:GCD complex subunit GCD6(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD6(gene name synonym)|uniprotkb:TIF225(gene name synonym)|uniprotkb:YD8142.12(orf name)|uniprotkb:YD8142B.03(orf name)|uniprotkb:YDR211W(locus name) psi-mi:"MI:0069"(mass spectrometry studies of complexes) Gordiyenko et al. (2013) pubmed:24852487|imex:IM-25313 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11711270|imex:IM-25313-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731 sgd:S000002619|refseq:NP_010497.3|dip:DIP-2328N|mint:P32501|ensemblfungi:YDR211W(gene)|ensemblfungi:YDR211W_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR001451(Bacterial transferase hexapeptide repeat)|interpro:IPR003307(eIF4-gamma/eIF5/eIF2-epsilon)|interpro:IPR005835(Nucleotidyl transferase)|interpro:IPR011004(Trimeric LpxA-like)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR029044|interpro:IPR035543|interpro:IPR044123|rcsb pdb:1PAQ|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731 - crc64:A5409FAF1594854C crc64:EFE87F6AE2941619 figure legend:Supp. Fig 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2016/06/01 2016/06/02 rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292 rogid:v70J4JmFrVbw38N8WqOg66aR634559292 rigid:u4htHhjsOBBGXifxTd1y+ZAR+PA false - - 1 2 psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P32502 uniprotkb:P09032 intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C intact:EBI-6275|uniprotkb:Q08721|uniprotkb:D6W2W1|ensemblfungi:YOR260W psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name) psi-mi:ei2bg_yeast(display_long)|uniprotkb:GCD1(gene name)|psi-mi:GCD1(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit gamma(gene name synonym)|uniprotkb:GCD complex subunit GCD1(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD1(gene name synonym)|uniprotkb:TIF223(gene name synonym)|uniprotkb:TRA3(gene name synonym)|uniprotkb:YOR260W(locus name) psi-mi:"MI:0069"(mass spectrometry studies of complexes) Gordiyenko et al. (2013) pubmed:24852487|imex:IM-25313 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11711270|imex:IM-25313-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731 refseq:NP_014903.1|sgd:S000005786|dip:DIP-1327N|mint:P09032|ensemblfungi:YOR260W(gene)|ensemblfungi:YOR260W_mRNA(transcript)|go:"GO:0002183"(cytoplasmic translational initiation)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:1903574"(negative regulation of cellular response to amino acid starvation)|interpro:IPR011004(Trimeric LpxA-like)|interpro:IPR029044|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731 - crc64:A5409FAF1594854C crc64:EC25BAE00F4D1E94 figure legend:Supp. Fig 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2016/06/01 2016/06/02 rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292 rogid:f7BMhuKpbYjQKxE4EmfcVgm6Zv4559292 rigid:u4htHhjsOBBGXifxTd1y+ZAR+PA false - flag tag:c-c|his tag:c-c 1 2 psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P32502 uniprotkb:P12754 intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C intact:EBI-6265|uniprotkb:D6VUL5|ensemblfungi:YGR083C psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name) psi-mi:ei2bd_yeast(display_long)|uniprotkb:GCD2(gene name)|psi-mi:GCD2(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit delta(gene name synonym)|uniprotkb:GCD complex subunit GCD2(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD2(gene name synonym)|uniprotkb:TIF224(gene name synonym)|uniprotkb:YGR083C(locus name) psi-mi:"MI:0069"(mass spectrometry studies of complexes) Gordiyenko et al. (2013) pubmed:24852487|imex:IM-25313 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-11711279|imex:IM-25313-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731 refseq:NP_011597.1|sgd:S000003315|dip:DIP-2343N|mint:P12754|ensemblfungi:YGR083C(gene)|ensemblfungi:YGR083C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR037171|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731 - crc64:A5409FAF1594854C crc64:B188457543CE1AAE figure legend:Supp. Fig. 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2016/06/01 2016/06/02 rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292 rogid:q04UNg7w1BfegEmJy01O+BDTJno559292 rigid:u4htHhjsOBBGXifxTd1y+ZAR+PA false - - 2 2 psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P32502 uniprotkb:P32501 intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C intact:EBI-6270|uniprotkb:D6VSJ5|ensemblfungi:YDR211W psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name) psi-mi:ei2be_yeast(display_long)|uniprotkb:GCD6(gene name)|psi-mi:GCD6(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit epsilon(gene name synonym)|uniprotkb:GCD complex subunit GCD6(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD6(gene name synonym)|uniprotkb:TIF225(gene name synonym)|uniprotkb:YD8142.12(orf name)|uniprotkb:YD8142B.03(orf name)|uniprotkb:YDR211W(locus name) psi-mi:"MI:0069"(mass spectrometry studies of complexes) Gordiyenko et al. (2013) pubmed:24852487|imex:IM-25313 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-11711279|imex:IM-25313-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731 sgd:S000002619|refseq:NP_010497.3|dip:DIP-2328N|mint:P32501|ensemblfungi:YDR211W(gene)|ensemblfungi:YDR211W_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR001451(Bacterial transferase hexapeptide repeat)|interpro:IPR003307(eIF4-gamma/eIF5/eIF2-epsilon)|interpro:IPR005835(Nucleotidyl transferase)|interpro:IPR011004(Trimeric LpxA-like)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR029044|interpro:IPR035543|interpro:IPR044123|rcsb pdb:1PAQ|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731 - crc64:A5409FAF1594854C crc64:EFE87F6AE2941619 figure legend:Supp. Fig. 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2016/06/01 2016/06/02 rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292 rogid:v70J4JmFrVbw38N8WqOg66aR634559292 rigid:u4htHhjsOBBGXifxTd1y+ZAR+PA false - - 2 1 psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P32502 uniprotkb:P09032 intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C intact:EBI-6275|uniprotkb:Q08721|uniprotkb:D6W2W1|ensemblfungi:YOR260W psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name) psi-mi:ei2bg_yeast(display_long)|uniprotkb:GCD1(gene name)|psi-mi:GCD1(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit gamma(gene name synonym)|uniprotkb:GCD complex subunit GCD1(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD1(gene name synonym)|uniprotkb:TIF223(gene name synonym)|uniprotkb:TRA3(gene name synonym)|uniprotkb:YOR260W(locus name) psi-mi:"MI:0069"(mass spectrometry studies of complexes) Gordiyenko et al. (2013) pubmed:24852487|imex:IM-25313 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-11711279|imex:IM-25313-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731 refseq:NP_014903.1|sgd:S000005786|dip:DIP-1327N|mint:P09032|ensemblfungi:YOR260W(gene)|ensemblfungi:YOR260W_mRNA(transcript)|go:"GO:0002183"(cytoplasmic translational initiation)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:1903574"(negative regulation of cellular response to amino acid starvation)|interpro:IPR011004(Trimeric LpxA-like)|interpro:IPR029044|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731 - crc64:A5409FAF1594854C crc64:EC25BAE00F4D1E94 figure legend:Supp. Fig. 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2016/06/01 2016/06/02 rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292 rogid:f7BMhuKpbYjQKxE4EmfcVgm6Zv4559292 rigid:u4htHhjsOBBGXifxTd1y+ZAR+PA false - flag tag:c-c|his tag:c-c 2 2 psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P32502 uniprotkb:P12754 intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C intact:EBI-6265|uniprotkb:D6VUL5|ensemblfungi:YGR083C psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name) psi-mi:ei2bd_yeast(display_long)|uniprotkb:GCD2(gene name)|psi-mi:GCD2(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit delta(gene name synonym)|uniprotkb:GCD complex subunit GCD2(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD2(gene name synonym)|uniprotkb:TIF224(gene name synonym)|uniprotkb:YGR083C(locus name) psi-mi:"MI:0069"(mass spectrometry studies of complexes) Gordiyenko et al. (2013) pubmed:24852487|imex:IM-25313 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-11711292|imex:IM-25313-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731 refseq:NP_011597.1|sgd:S000003315|dip:DIP-2343N|mint:P12754|ensemblfungi:YGR083C(gene)|ensemblfungi:YGR083C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR037171|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731 - crc64:A5409FAF1594854C crc64:B188457543CE1AAE figure legend:Supp. Fig. 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2016/06/01 2016/06/02 rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292 rogid:q04UNg7w1BfegEmJy01O+BDTJno559292 rigid:u4htHhjsOBBGXifxTd1y+ZAR+PA false - - 2 1 psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P32502 uniprotkb:P32501 intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C intact:EBI-6270|uniprotkb:D6VSJ5|ensemblfungi:YDR211W psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name) psi-mi:ei2be_yeast(display_long)|uniprotkb:GCD6(gene name)|psi-mi:GCD6(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit epsilon(gene name synonym)|uniprotkb:GCD complex subunit GCD6(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD6(gene name synonym)|uniprotkb:TIF225(gene name synonym)|uniprotkb:YD8142.12(orf name)|uniprotkb:YD8142B.03(orf name)|uniprotkb:YDR211W(locus name) psi-mi:"MI:0069"(mass spectrometry studies of complexes) Gordiyenko et al. (2013) pubmed:24852487|imex:IM-25313 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-11711292|imex:IM-25313-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731 sgd:S000002619|refseq:NP_010497.3|dip:DIP-2328N|mint:P32501|ensemblfungi:YDR211W(gene)|ensemblfungi:YDR211W_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR001451(Bacterial transferase hexapeptide repeat)|interpro:IPR003307(eIF4-gamma/eIF5/eIF2-epsilon)|interpro:IPR005835(Nucleotidyl transferase)|interpro:IPR011004(Trimeric LpxA-like)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR029044|interpro:IPR035543|interpro:IPR044123|rcsb pdb:1PAQ|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731 - crc64:A5409FAF1594854C crc64:EFE87F6AE2941619 figure legend:Supp. Fig. 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2016/06/01 2016/06/02 rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292 rogid:v70J4JmFrVbw38N8WqOg66aR634559292 rigid:u4htHhjsOBBGXifxTd1y+ZAR+PA false - - 2 2 psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P32502 uniprotkb:P09032 intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C intact:EBI-6275|uniprotkb:Q08721|uniprotkb:D6W2W1|ensemblfungi:YOR260W psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name) psi-mi:ei2bg_yeast(display_long)|uniprotkb:GCD1(gene name)|psi-mi:GCD1(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit gamma(gene name synonym)|uniprotkb:GCD complex subunit GCD1(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD1(gene name synonym)|uniprotkb:TIF223(gene name synonym)|uniprotkb:TRA3(gene name synonym)|uniprotkb:YOR260W(locus name) psi-mi:"MI:0069"(mass spectrometry studies of complexes) Gordiyenko et al. (2013) pubmed:24852487|imex:IM-25313 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-11711292|imex:IM-25313-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731 refseq:NP_014903.1|sgd:S000005786|dip:DIP-1327N|mint:P09032|ensemblfungi:YOR260W(gene)|ensemblfungi:YOR260W_mRNA(transcript)|go:"GO:0002183"(cytoplasmic translational initiation)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:1903574"(negative regulation of cellular response to amino acid starvation)|interpro:IPR011004(Trimeric LpxA-like)|interpro:IPR029044|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731 - crc64:A5409FAF1594854C crc64:EC25BAE00F4D1E94 figure legend:Supp. Fig. 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2016/06/01 2016/06/02 rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292 rogid:f7BMhuKpbYjQKxE4EmfcVgm6Zv4559292 rigid:u4htHhjsOBBGXifxTd1y+ZAR+PA false - flag tag:c-c|his tag:c-c 2 2 psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P09032 uniprotkb:P32501 intact:EBI-6275|uniprotkb:Q08721|uniprotkb:D6W2W1|ensemblfungi:YOR260W intact:EBI-6270|uniprotkb:D6VSJ5|ensemblfungi:YDR211W psi-mi:ei2bg_yeast(display_long)|uniprotkb:GCD1(gene name)|psi-mi:GCD1(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit gamma(gene name synonym)|uniprotkb:GCD complex subunit GCD1(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD1(gene name synonym)|uniprotkb:TIF223(gene name synonym)|uniprotkb:TRA3(gene name synonym)|uniprotkb:YOR260W(locus name) psi-mi:ei2be_yeast(display_long)|uniprotkb:GCD6(gene name)|psi-mi:GCD6(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit epsilon(gene name synonym)|uniprotkb:GCD complex subunit GCD6(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD6(gene name synonym)|uniprotkb:TIF225(gene name synonym)|uniprotkb:YD8142.12(orf name)|uniprotkb:YD8142B.03(orf name)|uniprotkb:YDR211W(locus name) psi-mi:"MI:0069"(mass spectrometry studies of complexes) Gordiyenko et al. (2013) pubmed:24852487|imex:IM-25313 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-12501208|imex:IM-25313-36 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014903.1|sgd:S000005786|dip:DIP-1327N|mint:P09032|ensemblfungi:YOR260W(gene)|ensemblfungi:YOR260W_mRNA(transcript)|go:"GO:0002183"(cytoplasmic translational initiation)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:1903574"(negative regulation of cellular response to amino acid starvation)|interpro:IPR011004(Trimeric LpxA-like)|interpro:IPR029044|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731 sgd:S000002619|refseq:NP_010497.3|dip:DIP-2328N|mint:P32501|ensemblfungi:YDR211W(gene)|ensemblfungi:YDR211W_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR001451(Bacterial transferase hexapeptide repeat)|interpro:IPR003307(eIF4-gamma/eIF5/eIF2-epsilon)|interpro:IPR005835(Nucleotidyl transferase)|interpro:IPR011004(Trimeric LpxA-like)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR029044|interpro:IPR035543|interpro:IPR044123|rcsb pdb:1PAQ|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731 - crc64:EC25BAE00F4D1E94 crc64:EFE87F6AE2941619 figure legend:Fig. 2A, 2B, 2C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2016/06/01 2016/08/09 rogid:f7BMhuKpbYjQKxE4EmfcVgm6Zv4559292 rogid:v70J4JmFrVbw38N8WqOg66aR634559292 rigid:vJAgzcRddGZnbttTHaR/vUM/JGk false flag tag:c-c|his tag:c-c - 1 1 psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P32481 uniprotkb:P09064 intact:EBI-8924|ensemblfungi:YER025W|uniprotkb:D3DLS4 intact:EBI-8920|ensemblfungi:YPL237W|uniprotkb:Q6B200|uniprotkb:D6W3D3 psi-mi:if2g_yeast(display_long)|uniprotkb:YER025W(locus name)|uniprotkb:GCD11(gene name)|psi-mi:GCD11(display_short)|uniprotkb:TIF213(gene name synonym)|uniprotkb:SUI4(gene name synonym) psi-mi:if2b_yeast(display_long)|uniprotkb:YPL237W(locus name)|uniprotkb:SUI3(gene name)|psi-mi:SUI3(display_short)|uniprotkb:TIF212(gene name synonym) psi-mi:"MI:0096"(pull down) Gordiyenko et al. (2013) pubmed:24852487|imex:IM-25313 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-11711222|imex:IM-25313-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-156827|reactome:R-SCE-381042|reactome:R-SCE-72649|reactome:R-SCE-72695|reactome:R-SCE-72702|reactome:R-SCE-72731|ensemblfungi:YER025W(gene)|ensemblfungi:YER025W_mRNA(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005850"(eukaryotic translation initiation factor 2 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0043614"(multi-eIF complex)|go:"GO:0045903"(positive regulation of translational fidelity)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR015256(Initiation factor eIF2 gamma, C terminal)|interpro:IPR027417|interpro:IPR044127|interpro:IPR044128|rcsb pdb:3J81|rcsb pdb:3JAP|rcsb pdb:3JAQ|rcsb pdb:4ZGN|rcsb pdb:4ZGQ|rcsb pdb:6FYX|rcsb pdb:6FYY|rcsb pdb:6GSM|rcsb pdb:6GSN|refseq:NP_010942.1|sgd:S000000827|mint:P32481|dip:DIP-2561N ensemblfungi:YPL237W(gene)|ensemblfungi:YPL237W_mRNA(transcript)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005850"(eukaryotic translation initiation factor 2 complex)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0043614"(multi-eIF complex)|go:"GO:0046872"(metal ion binding)|interpro:IPR002735(Translation initiation factor IF2/IF5)|interpro:IPR016189(Translation initiation factor IF2/IF5, N-terminal)|interpro:IPR016190(Translation initiation factor IF2/IF5, zinc-binding)|rcsb pdb:3J81|rcsb pdb:3JAP|rcsb pdb:3JAQ|rcsb pdb:6FYX|rcsb pdb:6FYY|rcsb pdb:6GSM|rcsb pdb:6GSN|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72649|refseq:NP_015087.1|sgd:S000006158|reactome:R-SCE-156827|reactome:R-SCE-72695|reactome:R-SCE-72702|reactome:R-SCE-72731|dip:DIP-2310N|reactome:R-SCE-381042 - crc64:D498AE62BC3E81CD crc64:34DE9323876CEE95 figure legend:Fig. 1A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2016/06/01 2016/06/02 rogid:KLaBewFsp1tygK0+hirsBIaMPEI559292 rogid:64fjjpMNrNM6gZW2BzacUQWRC1I559292 rigid:qTPyHktlj1ToFFmcNf8R0+DycuI false his tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P32481 uniprotkb:P20459 intact:EBI-8924|ensemblfungi:YER025W|uniprotkb:D3DLS4 intact:EBI-8915|uniprotkb:E9P8T6|ensemblfungi:YJR007W|uniprotkb:D6VWI2 psi-mi:if2g_yeast(display_long)|uniprotkb:YER025W(locus name)|uniprotkb:GCD11(gene name)|psi-mi:GCD11(display_short)|uniprotkb:TIF213(gene name synonym)|uniprotkb:SUI4(gene name synonym) psi-mi:if2a_yeast(display_long)|uniprotkb:SUI2(gene name)|psi-mi:SUI2(display_short)|uniprotkb:TIF211(gene name synonym)|uniprotkb:YJR007W(locus name)|uniprotkb:J1429(orf name) psi-mi:"MI:0096"(pull down) Gordiyenko et al. (2013) pubmed:24852487|imex:IM-25313 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-11711222|imex:IM-25313-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-156827|reactome:R-SCE-381042|reactome:R-SCE-72649|reactome:R-SCE-72695|reactome:R-SCE-72702|reactome:R-SCE-72731|ensemblfungi:YER025W(gene)|ensemblfungi:YER025W_mRNA(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005850"(eukaryotic translation initiation factor 2 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0043614"(multi-eIF complex)|go:"GO:0045903"(positive regulation of translational fidelity)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR015256(Initiation factor eIF2 gamma, C terminal)|interpro:IPR027417|interpro:IPR044127|interpro:IPR044128|rcsb pdb:3J81|rcsb pdb:3JAP|rcsb pdb:3JAQ|rcsb pdb:4ZGN|rcsb pdb:4ZGQ|rcsb pdb:6FYX|rcsb pdb:6FYY|rcsb pdb:6GSM|rcsb pdb:6GSN|refseq:NP_010942.1|sgd:S000000827|mint:P32481|dip:DIP-2561N interpro:IPR022967|interpro:IPR024054|interpro:IPR024055|interpro:IPR044126|rcsb pdb:1Q46|rcsb pdb:2A19|rcsb pdb:2A1A|rcsb pdb:3J81|rcsb pdb:3JAP|rcsb pdb:3JAQ|rcsb pdb:6FYX|rcsb pdb:6FYY|rcsb pdb:6GSM|rcsb pdb:6GSN|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6JLY|rcsb pdb:6JLZ|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-156827|reactome:R-SCE-381042|reactome:R-SCE-72649|reactome:R-SCE-72695|reactome:R-SCE-72702|reactome:R-SCE-72731|ensemblfungi:YJR007W(gene)|ensemblfungi:YJR007W_mRNA(transcript)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005850"(eukaryotic translation initiation factor 2 complex)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0043022"(ribosome binding)|go:"GO:0043614"(multi-eIF complex)|interpro:IPR003029(S1, RNA binding)|interpro:IPR011488(Eukaryotic translation initiation factor 2, alpha subunit)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|refseq:NP_012540.3|sgd:S000003767|mint:P20459|dip:DIP-2327N - crc64:D498AE62BC3E81CD crc64:AF4F1C80303A4E98 figure legend:Fig. 1A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2016/06/01 2016/06/02 rogid:KLaBewFsp1tygK0+hirsBIaMPEI559292 rogid:9/iGImP9/c8HSYwgmItME27z7lE559292 rigid:qTPyHktlj1ToFFmcNf8R0+DycuI false his tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P09032 uniprotkb:P32502 intact:EBI-6275|uniprotkb:Q08721|uniprotkb:D6W2W1|ensemblfungi:YOR260W intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C psi-mi:ei2bg_yeast(display_long)|uniprotkb:GCD1(gene name)|psi-mi:GCD1(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit gamma(gene name synonym)|uniprotkb:GCD complex subunit GCD1(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD1(gene name synonym)|uniprotkb:TIF223(gene name synonym)|uniprotkb:TRA3(gene name synonym)|uniprotkb:YOR260W(locus name) psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Gordiyenko et al. (2013) pubmed:24852487|imex:IM-25313 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-11711229|imex:IM-25313-30 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014903.1|sgd:S000005786|dip:DIP-1327N|mint:P09032|ensemblfungi:YOR260W(gene)|ensemblfungi:YOR260W_mRNA(transcript)|go:"GO:0002183"(cytoplasmic translational initiation)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:1903574"(negative regulation of cellular response to amino acid starvation)|interpro:IPR011004(Trimeric LpxA-like)|interpro:IPR029044|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731 refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731 - crc64:EC25BAE00F4D1E94 crc64:A5409FAF1594854C figure legend:Fig. 1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2016/06/01 2016/06/02 rogid:f7BMhuKpbYjQKxE4EmfcVgm6Zv4559292 rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292 rigid:HjskxmufgC71B3axXvUyCtDNCGc false his tag:c-c|flag tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P09032 uniprotkb:P12754 intact:EBI-6275|uniprotkb:Q08721|uniprotkb:D6W2W1|ensemblfungi:YOR260W intact:EBI-6265|uniprotkb:D6VUL5|ensemblfungi:YGR083C psi-mi:ei2bg_yeast(display_long)|uniprotkb:GCD1(gene name)|psi-mi:GCD1(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit gamma(gene name synonym)|uniprotkb:GCD complex subunit GCD1(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD1(gene name synonym)|uniprotkb:TIF223(gene name synonym)|uniprotkb:TRA3(gene name synonym)|uniprotkb:YOR260W(locus name) psi-mi:ei2bd_yeast(display_long)|uniprotkb:GCD2(gene name)|psi-mi:GCD2(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit delta(gene name synonym)|uniprotkb:GCD complex subunit GCD2(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD2(gene name synonym)|uniprotkb:TIF224(gene name synonym)|uniprotkb:YGR083C(locus name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Gordiyenko et al. (2013) pubmed:24852487|imex:IM-25313 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-11711229|imex:IM-25313-30 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014903.1|sgd:S000005786|dip:DIP-1327N|mint:P09032|ensemblfungi:YOR260W(gene)|ensemblfungi:YOR260W_mRNA(transcript)|go:"GO:0002183"(cytoplasmic translational initiation)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:1903574"(negative regulation of cellular response to amino acid starvation)|interpro:IPR011004(Trimeric LpxA-like)|interpro:IPR029044|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731 refseq:NP_011597.1|sgd:S000003315|dip:DIP-2343N|mint:P12754|ensemblfungi:YGR083C(gene)|ensemblfungi:YGR083C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR037171|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731 - crc64:EC25BAE00F4D1E94 crc64:B188457543CE1AAE figure legend:Fig. 1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2016/06/01 2016/06/02 rogid:f7BMhuKpbYjQKxE4EmfcVgm6Zv4559292 rogid:q04UNg7w1BfegEmJy01O+BDTJno559292 rigid:HjskxmufgC71B3axXvUyCtDNCGc false his tag:c-c|flag tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P09032 uniprotkb:P32501 intact:EBI-6275|uniprotkb:Q08721|uniprotkb:D6W2W1|ensemblfungi:YOR260W intact:EBI-6270|uniprotkb:D6VSJ5|ensemblfungi:YDR211W psi-mi:ei2bg_yeast(display_long)|uniprotkb:GCD1(gene name)|psi-mi:GCD1(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit gamma(gene name synonym)|uniprotkb:GCD complex subunit GCD1(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD1(gene name synonym)|uniprotkb:TIF223(gene name synonym)|uniprotkb:TRA3(gene name synonym)|uniprotkb:YOR260W(locus name) psi-mi:ei2be_yeast(display_long)|uniprotkb:GCD6(gene name)|psi-mi:GCD6(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit epsilon(gene name synonym)|uniprotkb:GCD complex subunit GCD6(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD6(gene name synonym)|uniprotkb:TIF225(gene name synonym)|uniprotkb:YD8142.12(orf name)|uniprotkb:YD8142B.03(orf name)|uniprotkb:YDR211W(locus name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Gordiyenko et al. (2013) pubmed:24852487|imex:IM-25313 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-11711229|imex:IM-25313-30 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014903.1|sgd:S000005786|dip:DIP-1327N|mint:P09032|ensemblfungi:YOR260W(gene)|ensemblfungi:YOR260W_mRNA(transcript)|go:"GO:0002183"(cytoplasmic translational initiation)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:1903574"(negative regulation of cellular response to amino acid starvation)|interpro:IPR011004(Trimeric LpxA-like)|interpro:IPR029044|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731 sgd:S000002619|refseq:NP_010497.3|dip:DIP-2328N|mint:P32501|ensemblfungi:YDR211W(gene)|ensemblfungi:YDR211W_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR001451(Bacterial transferase hexapeptide repeat)|interpro:IPR003307(eIF4-gamma/eIF5/eIF2-epsilon)|interpro:IPR005835(Nucleotidyl transferase)|interpro:IPR011004(Trimeric LpxA-like)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR029044|interpro:IPR035543|interpro:IPR044123|rcsb pdb:1PAQ|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731 - crc64:EC25BAE00F4D1E94 crc64:EFE87F6AE2941619 figure legend:Fig. 1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2016/06/01 2016/06/02 rogid:f7BMhuKpbYjQKxE4EmfcVgm6Zv4559292 rogid:v70J4JmFrVbw38N8WqOg66aR634559292 rigid:HjskxmufgC71B3axXvUyCtDNCGc false his tag:c-c|flag tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P09032 uniprotkb:P14741 intact:EBI-6275|uniprotkb:Q08721|uniprotkb:D6W2W1|ensemblfungi:YOR260W intact:EBI-6253|uniprotkb:D6VX91|ensemblfungi:YKR026C psi-mi:ei2bg_yeast(display_long)|uniprotkb:GCD1(gene name)|psi-mi:GCD1(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit gamma(gene name synonym)|uniprotkb:GCD complex subunit GCD1(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD1(gene name synonym)|uniprotkb:TIF223(gene name synonym)|uniprotkb:TRA3(gene name synonym)|uniprotkb:YOR260W(locus name) psi-mi:ei2ba_yeast(display_long)|uniprotkb:GCN3(gene name)|psi-mi:GCN3(display_short)|uniprotkb:AAS2(gene name synonym)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit alpha(gene name synonym)|uniprotkb:GCD complex subunit GCN3(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCN3(gene name synonym)|uniprotkb:TIF221(gene name synonym)|uniprotkb:YKR026C(locus name)|uniprotkb:Translational activator GCN3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Gordiyenko et al. (2013) pubmed:24852487|imex:IM-25313 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-11711229|imex:IM-25313-30 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014903.1|sgd:S000005786|dip:DIP-1327N|mint:P09032|ensemblfungi:YOR260W(gene)|ensemblfungi:YOR260W_mRNA(transcript)|go:"GO:0002183"(cytoplasmic translational initiation)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:1903574"(negative regulation of cellular response to amino acid starvation)|interpro:IPR011004(Trimeric LpxA-like)|interpro:IPR029044|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731 refseq:NP_012951.1|sgd:S000001734|dip:DIP-1328N|mint:P14741|ensemblfungi:YKR026C(gene)|ensemblfungi:YKR026C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|go:"GO:1903833"(positive regulation of cellular response to amino acid starvation)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR037171|interpro:IPR042528|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731 - crc64:EC25BAE00F4D1E94 crc64:8E9A928D6D56E12B figure legend:Fig. 1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2016/06/01 2016/06/02 rogid:f7BMhuKpbYjQKxE4EmfcVgm6Zv4559292 rogid:Nm+Ahop9EG8SQNZbo6+usIB9SAY559292 rigid:HjskxmufgC71B3axXvUyCtDNCGc false his tag:c-c|flag tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P09032 uniprotkb:P20459 intact:EBI-6275|uniprotkb:Q08721|uniprotkb:D6W2W1|ensemblfungi:YOR260W intact:EBI-8915|uniprotkb:E9P8T6|ensemblfungi:YJR007W|uniprotkb:D6VWI2 psi-mi:ei2bg_yeast(display_long)|uniprotkb:GCD1(gene name)|psi-mi:GCD1(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit gamma(gene name synonym)|uniprotkb:GCD complex subunit GCD1(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD1(gene name synonym)|uniprotkb:TIF223(gene name synonym)|uniprotkb:TRA3(gene name synonym)|uniprotkb:YOR260W(locus name) psi-mi:if2a_yeast(display_long)|uniprotkb:SUI2(gene name)|psi-mi:SUI2(display_short)|uniprotkb:TIF211(gene name synonym)|uniprotkb:YJR007W(locus name)|uniprotkb:J1429(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Gordiyenko et al. (2013) pubmed:24852487|imex:IM-25313 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-11711309|imex:IM-25313-25 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014903.1|sgd:S000005786|dip:DIP-1327N|mint:P09032|ensemblfungi:YOR260W(gene)|ensemblfungi:YOR260W_mRNA(transcript)|go:"GO:0002183"(cytoplasmic translational initiation)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:1903574"(negative regulation of cellular response to amino acid starvation)|interpro:IPR011004(Trimeric LpxA-like)|interpro:IPR029044|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731 interpro:IPR022967|interpro:IPR024054|interpro:IPR024055|interpro:IPR044126|rcsb pdb:1Q46|rcsb pdb:2A19|rcsb pdb:2A1A|rcsb pdb:3J81|rcsb pdb:3JAP|rcsb pdb:3JAQ|rcsb pdb:6FYX|rcsb pdb:6FYY|rcsb pdb:6GSM|rcsb pdb:6GSN|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6JLY|rcsb pdb:6JLZ|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-156827|reactome:R-SCE-381042|reactome:R-SCE-72649|reactome:R-SCE-72695|reactome:R-SCE-72702|reactome:R-SCE-72731|ensemblfungi:YJR007W(gene)|ensemblfungi:YJR007W_mRNA(transcript)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005850"(eukaryotic translation initiation factor 2 complex)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0043022"(ribosome binding)|go:"GO:0043614"(multi-eIF complex)|interpro:IPR003029(S1, RNA binding)|interpro:IPR011488(Eukaryotic translation initiation factor 2, alpha subunit)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|refseq:NP_012540.3|sgd:S000003767|mint:P20459|dip:DIP-2327N - crc64:EC25BAE00F4D1E94 crc64:AF4F1C80303A4E98 figure legend:Supp. Fig. 3A, 3B|comment:The eIF2 and eIF2B interact weakly.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2016/06/01 2016/06/06 rogid:f7BMhuKpbYjQKxE4EmfcVgm6Zv4559292 rogid:9/iGImP9/c8HSYwgmItME27z7lE559292 rigid:InOyJpbjEalkyN/RgBBBhVRbwbE false his tag:c-c|flag tag:c-c O-phospho-L-serine:52-52 - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P09032 uniprotkb:P32481 intact:EBI-6275|uniprotkb:Q08721|uniprotkb:D6W2W1|ensemblfungi:YOR260W intact:EBI-8924|ensemblfungi:YER025W|uniprotkb:D3DLS4 psi-mi:ei2bg_yeast(display_long)|uniprotkb:GCD1(gene name)|psi-mi:GCD1(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit gamma(gene name synonym)|uniprotkb:GCD complex subunit GCD1(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD1(gene name synonym)|uniprotkb:TIF223(gene name synonym)|uniprotkb:TRA3(gene name synonym)|uniprotkb:YOR260W(locus name) psi-mi:if2g_yeast(display_long)|uniprotkb:YER025W(locus name)|uniprotkb:GCD11(gene name)|psi-mi:GCD11(display_short)|uniprotkb:TIF213(gene name synonym)|uniprotkb:SUI4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Gordiyenko et al. (2013) pubmed:24852487|imex:IM-25313 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-11711309|imex:IM-25313-25 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014903.1|sgd:S000005786|dip:DIP-1327N|mint:P09032|ensemblfungi:YOR260W(gene)|ensemblfungi:YOR260W_mRNA(transcript)|go:"GO:0002183"(cytoplasmic translational initiation)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:1903574"(negative regulation of cellular response to amino acid starvation)|interpro:IPR011004(Trimeric LpxA-like)|interpro:IPR029044|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731 rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-156827|reactome:R-SCE-381042|reactome:R-SCE-72649|reactome:R-SCE-72695|reactome:R-SCE-72702|reactome:R-SCE-72731|ensemblfungi:YER025W(gene)|ensemblfungi:YER025W_mRNA(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005850"(eukaryotic translation initiation factor 2 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0043614"(multi-eIF complex)|go:"GO:0045903"(positive regulation of translational fidelity)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR015256(Initiation factor eIF2 gamma, C terminal)|interpro:IPR027417|interpro:IPR044127|interpro:IPR044128|rcsb pdb:3J81|rcsb pdb:3JAP|rcsb pdb:3JAQ|rcsb pdb:4ZGN|rcsb pdb:4ZGQ|rcsb pdb:6FYX|rcsb pdb:6FYY|rcsb pdb:6GSM|rcsb pdb:6GSN|refseq:NP_010942.1|sgd:S000000827|mint:P32481|dip:DIP-2561N - crc64:EC25BAE00F4D1E94 crc64:D498AE62BC3E81CD figure legend:Supp. Fig. 3A, 3B|comment:The eIF2 and eIF2B interact weakly.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2016/06/01 2016/06/06 rogid:f7BMhuKpbYjQKxE4EmfcVgm6Zv4559292 rogid:KLaBewFsp1tygK0+hirsBIaMPEI559292 rigid:InOyJpbjEalkyN/RgBBBhVRbwbE false his tag:c-c|flag tag:c-c his tag:c-c - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P09032 uniprotkb:P09064 intact:EBI-6275|uniprotkb:Q08721|uniprotkb:D6W2W1|ensemblfungi:YOR260W intact:EBI-8920|ensemblfungi:YPL237W|uniprotkb:Q6B200|uniprotkb:D6W3D3 psi-mi:ei2bg_yeast(display_long)|uniprotkb:GCD1(gene name)|psi-mi:GCD1(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit gamma(gene name synonym)|uniprotkb:GCD complex subunit GCD1(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD1(gene name synonym)|uniprotkb:TIF223(gene name synonym)|uniprotkb:TRA3(gene name synonym)|uniprotkb:YOR260W(locus name) psi-mi:if2b_yeast(display_long)|uniprotkb:YPL237W(locus name)|uniprotkb:SUI3(gene name)|psi-mi:SUI3(display_short)|uniprotkb:TIF212(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Gordiyenko et al. (2013) pubmed:24852487|imex:IM-25313 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-11711309|imex:IM-25313-25 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014903.1|sgd:S000005786|dip:DIP-1327N|mint:P09032|ensemblfungi:YOR260W(gene)|ensemblfungi:YOR260W_mRNA(transcript)|go:"GO:0002183"(cytoplasmic translational initiation)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:1903574"(negative regulation of cellular response to amino acid starvation)|interpro:IPR011004(Trimeric LpxA-like)|interpro:IPR029044|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731 ensemblfungi:YPL237W(gene)|ensemblfungi:YPL237W_mRNA(transcript)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005850"(eukaryotic translation initiation factor 2 complex)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0043614"(multi-eIF complex)|go:"GO:0046872"(metal ion binding)|interpro:IPR002735(Translation initiation factor IF2/IF5)|interpro:IPR016189(Translation initiation factor IF2/IF5, N-terminal)|interpro:IPR016190(Translation initiation factor IF2/IF5, zinc-binding)|rcsb pdb:3J81|rcsb pdb:3JAP|rcsb pdb:3JAQ|rcsb pdb:6FYX|rcsb pdb:6FYY|rcsb pdb:6GSM|rcsb pdb:6GSN|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72649|refseq:NP_015087.1|sgd:S000006158|reactome:R-SCE-156827|reactome:R-SCE-72695|reactome:R-SCE-72702|reactome:R-SCE-72731|dip:DIP-2310N|reactome:R-SCE-381042 - crc64:EC25BAE00F4D1E94 crc64:34DE9323876CEE95 figure legend:Supp. Fig. 3A, 3B|comment:The eIF2 and eIF2B interact weakly.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2016/06/01 2016/06/06 rogid:f7BMhuKpbYjQKxE4EmfcVgm6Zv4559292 rogid:64fjjpMNrNM6gZW2BzacUQWRC1I559292 rigid:InOyJpbjEalkyN/RgBBBhVRbwbE false his tag:c-c|flag tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P09032 uniprotkb:P32502 intact:EBI-6275|uniprotkb:Q08721|uniprotkb:D6W2W1|ensemblfungi:YOR260W intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C psi-mi:ei2bg_yeast(display_long)|uniprotkb:GCD1(gene name)|psi-mi:GCD1(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit gamma(gene name synonym)|uniprotkb:GCD complex subunit GCD1(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD1(gene name synonym)|uniprotkb:TIF223(gene name synonym)|uniprotkb:TRA3(gene name synonym)|uniprotkb:YOR260W(locus name) psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Gordiyenko et al. (2013) pubmed:24852487|imex:IM-25313 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-11711309|imex:IM-25313-25 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014903.1|sgd:S000005786|dip:DIP-1327N|mint:P09032|ensemblfungi:YOR260W(gene)|ensemblfungi:YOR260W_mRNA(transcript)|go:"GO:0002183"(cytoplasmic translational initiation)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:1903574"(negative regulation of cellular response to amino acid starvation)|interpro:IPR011004(Trimeric LpxA-like)|interpro:IPR029044|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731 refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731 - crc64:EC25BAE00F4D1E94 crc64:A5409FAF1594854C figure legend:Supp. Fig. 3A, 3B|comment:The eIF2 and eIF2B interact weakly.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2016/06/01 2016/06/06 rogid:f7BMhuKpbYjQKxE4EmfcVgm6Zv4559292 rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292 rigid:InOyJpbjEalkyN/RgBBBhVRbwbE false his tag:c-c|flag tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P09032 uniprotkb:P12754 intact:EBI-6275|uniprotkb:Q08721|uniprotkb:D6W2W1|ensemblfungi:YOR260W intact:EBI-6265|uniprotkb:D6VUL5|ensemblfungi:YGR083C psi-mi:ei2bg_yeast(display_long)|uniprotkb:GCD1(gene name)|psi-mi:GCD1(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit gamma(gene name synonym)|uniprotkb:GCD complex subunit GCD1(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD1(gene name synonym)|uniprotkb:TIF223(gene name synonym)|uniprotkb:TRA3(gene name synonym)|uniprotkb:YOR260W(locus name) psi-mi:ei2bd_yeast(display_long)|uniprotkb:GCD2(gene name)|psi-mi:GCD2(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit delta(gene name synonym)|uniprotkb:GCD complex subunit GCD2(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD2(gene name synonym)|uniprotkb:TIF224(gene name synonym)|uniprotkb:YGR083C(locus name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Gordiyenko et al. (2013) pubmed:24852487|imex:IM-25313 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-11711309|imex:IM-25313-25 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014903.1|sgd:S000005786|dip:DIP-1327N|mint:P09032|ensemblfungi:YOR260W(gene)|ensemblfungi:YOR260W_mRNA(transcript)|go:"GO:0002183"(cytoplasmic translational initiation)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:1903574"(negative regulation of cellular response to amino acid starvation)|interpro:IPR011004(Trimeric LpxA-like)|interpro:IPR029044|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731 refseq:NP_011597.1|sgd:S000003315|dip:DIP-2343N|mint:P12754|ensemblfungi:YGR083C(gene)|ensemblfungi:YGR083C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR037171|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731 - crc64:EC25BAE00F4D1E94 crc64:B188457543CE1AAE figure legend:Supp. Fig. 3A, 3B|comment:The eIF2 and eIF2B interact weakly.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2016/06/01 2016/06/06 rogid:f7BMhuKpbYjQKxE4EmfcVgm6Zv4559292 rogid:q04UNg7w1BfegEmJy01O+BDTJno559292 rigid:InOyJpbjEalkyN/RgBBBhVRbwbE false his tag:c-c|flag tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P09032 uniprotkb:P32501 intact:EBI-6275|uniprotkb:Q08721|uniprotkb:D6W2W1|ensemblfungi:YOR260W intact:EBI-6270|uniprotkb:D6VSJ5|ensemblfungi:YDR211W psi-mi:ei2bg_yeast(display_long)|uniprotkb:GCD1(gene name)|psi-mi:GCD1(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit gamma(gene name synonym)|uniprotkb:GCD complex subunit GCD1(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD1(gene name synonym)|uniprotkb:TIF223(gene name synonym)|uniprotkb:TRA3(gene name synonym)|uniprotkb:YOR260W(locus name) psi-mi:ei2be_yeast(display_long)|uniprotkb:GCD6(gene name)|psi-mi:GCD6(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit epsilon(gene name synonym)|uniprotkb:GCD complex subunit GCD6(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD6(gene name synonym)|uniprotkb:TIF225(gene name synonym)|uniprotkb:YD8142.12(orf name)|uniprotkb:YD8142B.03(orf name)|uniprotkb:YDR211W(locus name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Gordiyenko et al. (2013) pubmed:24852487|imex:IM-25313 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-11711309|imex:IM-25313-25 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014903.1|sgd:S000005786|dip:DIP-1327N|mint:P09032|ensemblfungi:YOR260W(gene)|ensemblfungi:YOR260W_mRNA(transcript)|go:"GO:0002183"(cytoplasmic translational initiation)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:1903574"(negative regulation of cellular response to amino acid starvation)|interpro:IPR011004(Trimeric LpxA-like)|interpro:IPR029044|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731 sgd:S000002619|refseq:NP_010497.3|dip:DIP-2328N|mint:P32501|ensemblfungi:YDR211W(gene)|ensemblfungi:YDR211W_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR001451(Bacterial transferase hexapeptide repeat)|interpro:IPR003307(eIF4-gamma/eIF5/eIF2-epsilon)|interpro:IPR005835(Nucleotidyl transferase)|interpro:IPR011004(Trimeric LpxA-like)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR029044|interpro:IPR035543|interpro:IPR044123|rcsb pdb:1PAQ|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731 - crc64:EC25BAE00F4D1E94 crc64:EFE87F6AE2941619 figure legend:Supp. Fig. 3A, 3B|comment:The eIF2 and eIF2B interact weakly.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2016/06/01 2016/06/06 rogid:f7BMhuKpbYjQKxE4EmfcVgm6Zv4559292 rogid:v70J4JmFrVbw38N8WqOg66aR634559292 rigid:InOyJpbjEalkyN/RgBBBhVRbwbE false his tag:c-c|flag tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P09032 uniprotkb:P14741 intact:EBI-6275|uniprotkb:Q08721|uniprotkb:D6W2W1|ensemblfungi:YOR260W intact:EBI-6253|uniprotkb:D6VX91|ensemblfungi:YKR026C psi-mi:ei2bg_yeast(display_long)|uniprotkb:GCD1(gene name)|psi-mi:GCD1(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit gamma(gene name synonym)|uniprotkb:GCD complex subunit GCD1(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD1(gene name synonym)|uniprotkb:TIF223(gene name synonym)|uniprotkb:TRA3(gene name synonym)|uniprotkb:YOR260W(locus name) psi-mi:ei2ba_yeast(display_long)|uniprotkb:GCN3(gene name)|psi-mi:GCN3(display_short)|uniprotkb:AAS2(gene name synonym)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit alpha(gene name synonym)|uniprotkb:GCD complex subunit GCN3(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCN3(gene name synonym)|uniprotkb:TIF221(gene name synonym)|uniprotkb:YKR026C(locus name)|uniprotkb:Translational activator GCN3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Gordiyenko et al. (2013) pubmed:24852487|imex:IM-25313 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-11711309|imex:IM-25313-25 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014903.1|sgd:S000005786|dip:DIP-1327N|mint:P09032|ensemblfungi:YOR260W(gene)|ensemblfungi:YOR260W_mRNA(transcript)|go:"GO:0002183"(cytoplasmic translational initiation)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:1903574"(negative regulation of cellular response to amino acid starvation)|interpro:IPR011004(Trimeric LpxA-like)|interpro:IPR029044|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731 refseq:NP_012951.1|sgd:S000001734|dip:DIP-1328N|mint:P14741|ensemblfungi:YKR026C(gene)|ensemblfungi:YKR026C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|go:"GO:1903833"(positive regulation of cellular response to amino acid starvation)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR037171|interpro:IPR042528|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731 - crc64:EC25BAE00F4D1E94 crc64:8E9A928D6D56E12B figure legend:Supp. Fig. 3A, 3B|comment:The eIF2 and eIF2B interact weakly.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2016/06/01 2016/06/06 rogid:f7BMhuKpbYjQKxE4EmfcVgm6Zv4559292 rogid:Nm+Ahop9EG8SQNZbo6+usIB9SAY559292 rigid:InOyJpbjEalkyN/RgBBBhVRbwbE false his tag:c-c|flag tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P09032 uniprotkb:P32502 intact:EBI-6275|uniprotkb:Q08721|uniprotkb:D6W2W1|ensemblfungi:YOR260W intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C psi-mi:ei2bg_yeast(display_long)|uniprotkb:GCD1(gene name)|psi-mi:GCD1(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit gamma(gene name synonym)|uniprotkb:GCD complex subunit GCD1(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD1(gene name synonym)|uniprotkb:TIF223(gene name synonym)|uniprotkb:TRA3(gene name synonym)|uniprotkb:YOR260W(locus name) psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Gordiyenko et al. (2013) pubmed:24852487|imex:IM-25313 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-11892145|imex:IM-25313-34 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014903.1|sgd:S000005786|dip:DIP-1327N|mint:P09032|ensemblfungi:YOR260W(gene)|ensemblfungi:YOR260W_mRNA(transcript)|go:"GO:0002183"(cytoplasmic translational initiation)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:1903574"(negative regulation of cellular response to amino acid starvation)|interpro:IPR011004(Trimeric LpxA-like)|interpro:IPR029044|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731 refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731 - crc64:EC25BAE00F4D1E94 crc64:A5409FAF1594854C figure legend:Fig. 2A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2016/06/01 2016/07/18 rogid:f7BMhuKpbYjQKxE4EmfcVgm6Zv4559292 rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292 rigid:u4htHhjsOBBGXifxTd1y+ZAR+PA false his tag:c-c|flag tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P09032 uniprotkb:P12754 intact:EBI-6275|uniprotkb:Q08721|uniprotkb:D6W2W1|ensemblfungi:YOR260W intact:EBI-6265|uniprotkb:D6VUL5|ensemblfungi:YGR083C psi-mi:ei2bg_yeast(display_long)|uniprotkb:GCD1(gene name)|psi-mi:GCD1(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit gamma(gene name synonym)|uniprotkb:GCD complex subunit GCD1(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD1(gene name synonym)|uniprotkb:TIF223(gene name synonym)|uniprotkb:TRA3(gene name synonym)|uniprotkb:YOR260W(locus name) psi-mi:ei2bd_yeast(display_long)|uniprotkb:GCD2(gene name)|psi-mi:GCD2(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit delta(gene name synonym)|uniprotkb:GCD complex subunit GCD2(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD2(gene name synonym)|uniprotkb:TIF224(gene name synonym)|uniprotkb:YGR083C(locus name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Gordiyenko et al. (2013) pubmed:24852487|imex:IM-25313 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-11892145|imex:IM-25313-34 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014903.1|sgd:S000005786|dip:DIP-1327N|mint:P09032|ensemblfungi:YOR260W(gene)|ensemblfungi:YOR260W_mRNA(transcript)|go:"GO:0002183"(cytoplasmic translational initiation)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:1903574"(negative regulation of cellular response to amino acid starvation)|interpro:IPR011004(Trimeric LpxA-like)|interpro:IPR029044|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731 refseq:NP_011597.1|sgd:S000003315|dip:DIP-2343N|mint:P12754|ensemblfungi:YGR083C(gene)|ensemblfungi:YGR083C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR037171|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731 - crc64:EC25BAE00F4D1E94 crc64:B188457543CE1AAE figure legend:Fig. 2A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2016/06/01 2016/07/18 rogid:f7BMhuKpbYjQKxE4EmfcVgm6Zv4559292 rogid:q04UNg7w1BfegEmJy01O+BDTJno559292 rigid:u4htHhjsOBBGXifxTd1y+ZAR+PA false his tag:c-c|flag tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P09032 uniprotkb:P32501 intact:EBI-6275|uniprotkb:Q08721|uniprotkb:D6W2W1|ensemblfungi:YOR260W intact:EBI-6270|uniprotkb:D6VSJ5|ensemblfungi:YDR211W psi-mi:ei2bg_yeast(display_long)|uniprotkb:GCD1(gene name)|psi-mi:GCD1(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit gamma(gene name synonym)|uniprotkb:GCD complex subunit GCD1(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD1(gene name synonym)|uniprotkb:TIF223(gene name synonym)|uniprotkb:TRA3(gene name synonym)|uniprotkb:YOR260W(locus name) psi-mi:ei2be_yeast(display_long)|uniprotkb:GCD6(gene name)|psi-mi:GCD6(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit epsilon(gene name synonym)|uniprotkb:GCD complex subunit GCD6(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD6(gene name synonym)|uniprotkb:TIF225(gene name synonym)|uniprotkb:YD8142.12(orf name)|uniprotkb:YD8142B.03(orf name)|uniprotkb:YDR211W(locus name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Gordiyenko et al. (2013) pubmed:24852487|imex:IM-25313 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-11892145|imex:IM-25313-34 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014903.1|sgd:S000005786|dip:DIP-1327N|mint:P09032|ensemblfungi:YOR260W(gene)|ensemblfungi:YOR260W_mRNA(transcript)|go:"GO:0002183"(cytoplasmic translational initiation)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:1903574"(negative regulation of cellular response to amino acid starvation)|interpro:IPR011004(Trimeric LpxA-like)|interpro:IPR029044|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731 sgd:S000002619|refseq:NP_010497.3|dip:DIP-2328N|mint:P32501|ensemblfungi:YDR211W(gene)|ensemblfungi:YDR211W_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR001451(Bacterial transferase hexapeptide repeat)|interpro:IPR003307(eIF4-gamma/eIF5/eIF2-epsilon)|interpro:IPR005835(Nucleotidyl transferase)|interpro:IPR011004(Trimeric LpxA-like)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR029044|interpro:IPR035543|interpro:IPR044123|rcsb pdb:1PAQ|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731 - crc64:EC25BAE00F4D1E94 crc64:EFE87F6AE2941619 figure legend:Fig. 2A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2016/06/01 2016/07/18 rogid:f7BMhuKpbYjQKxE4EmfcVgm6Zv4559292 rogid:v70J4JmFrVbw38N8WqOg66aR634559292 rigid:u4htHhjsOBBGXifxTd1y+ZAR+PA false his tag:c-c|flag tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P14741 uniprotkb:P32502 intact:EBI-6253|uniprotkb:D6VX91|ensemblfungi:YKR026C intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C psi-mi:ei2ba_yeast(display_long)|uniprotkb:GCN3(gene name)|psi-mi:GCN3(display_short)|uniprotkb:AAS2(gene name synonym)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit alpha(gene name synonym)|uniprotkb:GCD complex subunit GCN3(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCN3(gene name synonym)|uniprotkb:TIF221(gene name synonym)|uniprotkb:YKR026C(locus name)|uniprotkb:Translational activator GCN3(gene name synonym) psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name) psi-mi:"MI:0030"(cross-linking study) Gordiyenko et al. (2013) pubmed:24852487|imex:IM-25313 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11711330|imex:IM-25313-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012951.1|sgd:S000001734|dip:DIP-1328N|mint:P14741|ensemblfungi:YKR026C(gene)|ensemblfungi:YKR026C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|go:"GO:1903833"(positive regulation of cellular response to amino acid starvation)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR037171|interpro:IPR042528|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731 refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731 - crc64:8E9A928D6D56E12B crc64:A5409FAF1594854C figure legend:Supp. Table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2016/06/01 2016/06/02 rogid:Nm+Ahop9EG8SQNZbo6+usIB9SAY559292 rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292 rigid:HjskxmufgC71B3axXvUyCtDNCGc false cross linker:107-107 cross linker:136-136|cross linker:380-380|cross linker:380-380|cross linker:329-329|cross linker:380-380 2 2 psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P14741 uniprotkb:P12754 intact:EBI-6253|uniprotkb:D6VX91|ensemblfungi:YKR026C intact:EBI-6265|uniprotkb:D6VUL5|ensemblfungi:YGR083C psi-mi:ei2ba_yeast(display_long)|uniprotkb:GCN3(gene name)|psi-mi:GCN3(display_short)|uniprotkb:AAS2(gene name synonym)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit alpha(gene name synonym)|uniprotkb:GCD complex subunit GCN3(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCN3(gene name synonym)|uniprotkb:TIF221(gene name synonym)|uniprotkb:YKR026C(locus name)|uniprotkb:Translational activator GCN3(gene name synonym) psi-mi:ei2bd_yeast(display_long)|uniprotkb:GCD2(gene name)|psi-mi:GCD2(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit delta(gene name synonym)|uniprotkb:GCD complex subunit GCD2(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD2(gene name synonym)|uniprotkb:TIF224(gene name synonym)|uniprotkb:YGR083C(locus name) psi-mi:"MI:0030"(cross-linking study) Gordiyenko et al. (2013) pubmed:24852487|imex:IM-25313 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11711330|imex:IM-25313-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012951.1|sgd:S000001734|dip:DIP-1328N|mint:P14741|ensemblfungi:YKR026C(gene)|ensemblfungi:YKR026C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|go:"GO:1903833"(positive regulation of cellular response to amino acid starvation)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR037171|interpro:IPR042528|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731 refseq:NP_011597.1|sgd:S000003315|dip:DIP-2343N|mint:P12754|ensemblfungi:YGR083C(gene)|ensemblfungi:YGR083C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR037171|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731 - crc64:8E9A928D6D56E12B crc64:B188457543CE1AAE figure legend:Supp. Table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2016/06/01 2016/06/02 rogid:Nm+Ahop9EG8SQNZbo6+usIB9SAY559292 rogid:q04UNg7w1BfegEmJy01O+BDTJno559292 rigid:HjskxmufgC71B3axXvUyCtDNCGc false cross linker:107-107 cross linker:648-648|cross linker:95-95|cross linker:570-570|cross linker:76-76|cross linker:422-422|cross linker:562-562|cross linker:570-570|cross linker:575-575|cross linker:579-579|cross linker:580-580|cross linker:564-564|cross linker:421-421|cross linker:133-133|cross linker:556-556|cross linker:559-559 2 2 psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P14741 uniprotkb:P32501 intact:EBI-6253|uniprotkb:D6VX91|ensemblfungi:YKR026C intact:EBI-6270|uniprotkb:D6VSJ5|ensemblfungi:YDR211W psi-mi:ei2ba_yeast(display_long)|uniprotkb:GCN3(gene name)|psi-mi:GCN3(display_short)|uniprotkb:AAS2(gene name synonym)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit alpha(gene name synonym)|uniprotkb:GCD complex subunit GCN3(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCN3(gene name synonym)|uniprotkb:TIF221(gene name synonym)|uniprotkb:YKR026C(locus name)|uniprotkb:Translational activator GCN3(gene name synonym) psi-mi:ei2be_yeast(display_long)|uniprotkb:GCD6(gene name)|psi-mi:GCD6(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit epsilon(gene name synonym)|uniprotkb:GCD complex subunit GCD6(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD6(gene name synonym)|uniprotkb:TIF225(gene name synonym)|uniprotkb:YD8142.12(orf name)|uniprotkb:YD8142B.03(orf name)|uniprotkb:YDR211W(locus name) psi-mi:"MI:0030"(cross-linking study) Gordiyenko et al. (2013) pubmed:24852487|imex:IM-25313 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11711330|imex:IM-25313-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012951.1|sgd:S000001734|dip:DIP-1328N|mint:P14741|ensemblfungi:YKR026C(gene)|ensemblfungi:YKR026C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|go:"GO:1903833"(positive regulation of cellular response to amino acid starvation)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR037171|interpro:IPR042528|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731 sgd:S000002619|refseq:NP_010497.3|dip:DIP-2328N|mint:P32501|ensemblfungi:YDR211W(gene)|ensemblfungi:YDR211W_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR001451(Bacterial transferase hexapeptide repeat)|interpro:IPR003307(eIF4-gamma/eIF5/eIF2-epsilon)|interpro:IPR005835(Nucleotidyl transferase)|interpro:IPR011004(Trimeric LpxA-like)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR029044|interpro:IPR035543|interpro:IPR044123|rcsb pdb:1PAQ|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731 - crc64:8E9A928D6D56E12B crc64:EFE87F6AE2941619 figure legend:Supp. Table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2016/06/01 2016/06/02 rogid:Nm+Ahop9EG8SQNZbo6+usIB9SAY559292 rogid:v70J4JmFrVbw38N8WqOg66aR634559292 rigid:HjskxmufgC71B3axXvUyCtDNCGc false cross linker:107-107 cross linker:9-9|cross linker:4-4|cross linker:356-356|cross linker:176-176|cross linker:176-176|cross linker:517-517|cross linker:519-519|cross linker:4-4 2 2 psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P14741 uniprotkb:P09032 intact:EBI-6253|uniprotkb:D6VX91|ensemblfungi:YKR026C intact:EBI-6275|uniprotkb:Q08721|uniprotkb:D6W2W1|ensemblfungi:YOR260W psi-mi:ei2ba_yeast(display_long)|uniprotkb:GCN3(gene name)|psi-mi:GCN3(display_short)|uniprotkb:AAS2(gene name synonym)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit alpha(gene name synonym)|uniprotkb:GCD complex subunit GCN3(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCN3(gene name synonym)|uniprotkb:TIF221(gene name synonym)|uniprotkb:YKR026C(locus name)|uniprotkb:Translational activator GCN3(gene name synonym) psi-mi:ei2bg_yeast(display_long)|uniprotkb:GCD1(gene name)|psi-mi:GCD1(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit gamma(gene name synonym)|uniprotkb:GCD complex subunit GCD1(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD1(gene name synonym)|uniprotkb:TIF223(gene name synonym)|uniprotkb:TRA3(gene name synonym)|uniprotkb:YOR260W(locus name) psi-mi:"MI:0030"(cross-linking study) Gordiyenko et al. (2013) pubmed:24852487|imex:IM-25313 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11711330|imex:IM-25313-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012951.1|sgd:S000001734|dip:DIP-1328N|mint:P14741|ensemblfungi:YKR026C(gene)|ensemblfungi:YKR026C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|go:"GO:1903833"(positive regulation of cellular response to amino acid starvation)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR037171|interpro:IPR042528|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731 refseq:NP_014903.1|sgd:S000005786|dip:DIP-1327N|mint:P09032|ensemblfungi:YOR260W(gene)|ensemblfungi:YOR260W_mRNA(transcript)|go:"GO:0002183"(cytoplasmic translational initiation)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:1903574"(negative regulation of cellular response to amino acid starvation)|interpro:IPR011004(Trimeric LpxA-like)|interpro:IPR029044|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731 - crc64:8E9A928D6D56E12B crc64:EC25BAE00F4D1E94 figure legend:Supp. Table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2016/06/01 2016/06/02 rogid:Nm+Ahop9EG8SQNZbo6+usIB9SAY559292 rogid:f7BMhuKpbYjQKxE4EmfcVgm6Zv4559292 rigid:HjskxmufgC71B3axXvUyCtDNCGc false cross linker:107-107 cross linker:412-412|cross linker:494-494|cross linker:410-410|cross linker:410-410|cross linker:410-410|cross linker:410-410|cross linker:410-410|cross linker:410-410|cross linker:249-249|cross linker:412-412|cross linker:376-376|cross linker:249-249|cross linker:249-249|cross linker:249-249|cross linker:410-410|flag tag:c-c|his tag:c-c 2 2 psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P20459 uniprotkb:P09064 intact:EBI-8915|uniprotkb:E9P8T6|ensemblfungi:YJR007W|uniprotkb:D6VWI2 intact:EBI-8920|ensemblfungi:YPL237W|uniprotkb:Q6B200|uniprotkb:D6W3D3 psi-mi:if2a_yeast(display_long)|uniprotkb:SUI2(gene name)|psi-mi:SUI2(display_short)|uniprotkb:TIF211(gene name synonym)|uniprotkb:YJR007W(locus name)|uniprotkb:J1429(orf name) psi-mi:if2b_yeast(display_long)|uniprotkb:YPL237W(locus name)|uniprotkb:SUI3(gene name)|psi-mi:SUI3(display_short)|uniprotkb:TIF212(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Gordiyenko et al. (2013) pubmed:24852487|imex:IM-25313 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11712083|imex:IM-25313-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR022967|interpro:IPR024054|interpro:IPR024055|interpro:IPR044126|rcsb pdb:1Q46|rcsb pdb:2A19|rcsb pdb:2A1A|rcsb pdb:3J81|rcsb pdb:3JAP|rcsb pdb:3JAQ|rcsb pdb:6FYX|rcsb pdb:6FYY|rcsb pdb:6GSM|rcsb pdb:6GSN|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6JLY|rcsb pdb:6JLZ|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-156827|reactome:R-SCE-381042|reactome:R-SCE-72649|reactome:R-SCE-72695|reactome:R-SCE-72702|reactome:R-SCE-72731|ensemblfungi:YJR007W(gene)|ensemblfungi:YJR007W_mRNA(transcript)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005850"(eukaryotic translation initiation factor 2 complex)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0043022"(ribosome binding)|go:"GO:0043614"(multi-eIF complex)|interpro:IPR003029(S1, RNA binding)|interpro:IPR011488(Eukaryotic translation initiation factor 2, alpha subunit)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|refseq:NP_012540.3|sgd:S000003767|mint:P20459|dip:DIP-2327N ensemblfungi:YPL237W(gene)|ensemblfungi:YPL237W_mRNA(transcript)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005850"(eukaryotic translation initiation factor 2 complex)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0043614"(multi-eIF complex)|go:"GO:0046872"(metal ion binding)|interpro:IPR002735(Translation initiation factor IF2/IF5)|interpro:IPR016189(Translation initiation factor IF2/IF5, N-terminal)|interpro:IPR016190(Translation initiation factor IF2/IF5, zinc-binding)|rcsb pdb:3J81|rcsb pdb:3JAP|rcsb pdb:3JAQ|rcsb pdb:6FYX|rcsb pdb:6FYY|rcsb pdb:6GSM|rcsb pdb:6GSN|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72649|refseq:NP_015087.1|sgd:S000006158|reactome:R-SCE-156827|reactome:R-SCE-72695|reactome:R-SCE-72702|reactome:R-SCE-72731|dip:DIP-2310N|reactome:R-SCE-381042 - crc64:AF4F1C80303A4E98 crc64:34DE9323876CEE95 figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2016/06/01 2016/06/03 rogid:9/iGImP9/c8HSYwgmItME27z7lE559292 rogid:64fjjpMNrNM6gZW2BzacUQWRC1I559292 rigid:qTPyHktlj1ToFFmcNf8R0+DycuI false cross linker:61-61|cross linker:61-61|cross linker:61-61|cross linker:61-61|cross linker:61-61|cross linker:61-61|cross linker:61-61|cross linker:183-183|cross linker:80-80 cross linker:170-170|cross linker:214-214|cross linker:272-272|cross linker:281-281|cross linker:260-260|cross linker:89-89|cross linker:102-102|cross linker:157-157|cross linker:54-54 - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P20459 uniprotkb:P32481 intact:EBI-8915|uniprotkb:E9P8T6|ensemblfungi:YJR007W|uniprotkb:D6VWI2 intact:EBI-8924|ensemblfungi:YER025W|uniprotkb:D3DLS4 psi-mi:if2a_yeast(display_long)|uniprotkb:SUI2(gene name)|psi-mi:SUI2(display_short)|uniprotkb:TIF211(gene name synonym)|uniprotkb:YJR007W(locus name)|uniprotkb:J1429(orf name) psi-mi:if2g_yeast(display_long)|uniprotkb:YER025W(locus name)|uniprotkb:GCD11(gene name)|psi-mi:GCD11(display_short)|uniprotkb:TIF213(gene name synonym)|uniprotkb:SUI4(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Gordiyenko et al. (2013) pubmed:24852487|imex:IM-25313 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11712083|imex:IM-25313-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR022967|interpro:IPR024054|interpro:IPR024055|interpro:IPR044126|rcsb pdb:1Q46|rcsb pdb:2A19|rcsb pdb:2A1A|rcsb pdb:3J81|rcsb pdb:3JAP|rcsb pdb:3JAQ|rcsb pdb:6FYX|rcsb pdb:6FYY|rcsb pdb:6GSM|rcsb pdb:6GSN|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6JLY|rcsb pdb:6JLZ|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-156827|reactome:R-SCE-381042|reactome:R-SCE-72649|reactome:R-SCE-72695|reactome:R-SCE-72702|reactome:R-SCE-72731|ensemblfungi:YJR007W(gene)|ensemblfungi:YJR007W_mRNA(transcript)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005850"(eukaryotic translation initiation factor 2 complex)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0043022"(ribosome binding)|go:"GO:0043614"(multi-eIF complex)|interpro:IPR003029(S1, RNA binding)|interpro:IPR011488(Eukaryotic translation initiation factor 2, alpha subunit)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|refseq:NP_012540.3|sgd:S000003767|mint:P20459|dip:DIP-2327N rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-156827|reactome:R-SCE-381042|reactome:R-SCE-72649|reactome:R-SCE-72695|reactome:R-SCE-72702|reactome:R-SCE-72731|ensemblfungi:YER025W(gene)|ensemblfungi:YER025W_mRNA(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005850"(eukaryotic translation initiation factor 2 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0043614"(multi-eIF complex)|go:"GO:0045903"(positive regulation of translational fidelity)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR015256(Initiation factor eIF2 gamma, C terminal)|interpro:IPR027417|interpro:IPR044127|interpro:IPR044128|rcsb pdb:3J81|rcsb pdb:3JAP|rcsb pdb:3JAQ|rcsb pdb:4ZGN|rcsb pdb:4ZGQ|rcsb pdb:6FYX|rcsb pdb:6FYY|rcsb pdb:6GSM|rcsb pdb:6GSN|refseq:NP_010942.1|sgd:S000000827|mint:P32481|dip:DIP-2561N - crc64:AF4F1C80303A4E98 crc64:D498AE62BC3E81CD figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2016/06/01 2016/06/03 rogid:9/iGImP9/c8HSYwgmItME27z7lE559292 rogid:KLaBewFsp1tygK0+hirsBIaMPEI559292 rigid:qTPyHktlj1ToFFmcNf8R0+DycuI false cross linker:61-61|cross linker:61-61|cross linker:61-61|cross linker:61-61|cross linker:61-61|cross linker:61-61|cross linker:61-61|cross linker:183-183|cross linker:80-80 his tag:c-c|cross linker:325-325|cross linker:129-129|cross linker:165-165|cross linker:268-268|cross linker:449-449|cross linker:452-452|cross linker:401-401|cross linker:268-268|cross linker:129-129|cross linker:165-165 - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P09032 uniprotkb:P20459 intact:EBI-6275|uniprotkb:Q08721|uniprotkb:D6W2W1|ensemblfungi:YOR260W intact:EBI-8915|uniprotkb:E9P8T6|ensemblfungi:YJR007W|uniprotkb:D6VWI2 psi-mi:ei2bg_yeast(display_long)|uniprotkb:GCD1(gene name)|psi-mi:GCD1(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit gamma(gene name synonym)|uniprotkb:GCD complex subunit GCD1(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD1(gene name synonym)|uniprotkb:TIF223(gene name synonym)|uniprotkb:TRA3(gene name synonym)|uniprotkb:YOR260W(locus name) psi-mi:if2a_yeast(display_long)|uniprotkb:SUI2(gene name)|psi-mi:SUI2(display_short)|uniprotkb:TIF211(gene name synonym)|uniprotkb:YJR007W(locus name)|uniprotkb:J1429(orf name) psi-mi:"MI:0030"(cross-linking study) Gordiyenko et al. (2013) pubmed:24852487|imex:IM-25313 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11712766|imex:IM-25313-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014903.1|sgd:S000005786|dip:DIP-1327N|mint:P09032|ensemblfungi:YOR260W(gene)|ensemblfungi:YOR260W_mRNA(transcript)|go:"GO:0002183"(cytoplasmic translational initiation)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:1903574"(negative regulation of cellular response to amino acid starvation)|interpro:IPR011004(Trimeric LpxA-like)|interpro:IPR029044|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731 interpro:IPR022967|interpro:IPR024054|interpro:IPR024055|interpro:IPR044126|rcsb pdb:1Q46|rcsb pdb:2A19|rcsb pdb:2A1A|rcsb pdb:3J81|rcsb pdb:3JAP|rcsb pdb:3JAQ|rcsb pdb:6FYX|rcsb pdb:6FYY|rcsb pdb:6GSM|rcsb pdb:6GSN|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6JLY|rcsb pdb:6JLZ|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-156827|reactome:R-SCE-381042|reactome:R-SCE-72649|reactome:R-SCE-72695|reactome:R-SCE-72702|reactome:R-SCE-72731|ensemblfungi:YJR007W(gene)|ensemblfungi:YJR007W_mRNA(transcript)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005850"(eukaryotic translation initiation factor 2 complex)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0043022"(ribosome binding)|go:"GO:0043614"(multi-eIF complex)|interpro:IPR003029(S1, RNA binding)|interpro:IPR011488(Eukaryotic translation initiation factor 2, alpha subunit)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|refseq:NP_012540.3|sgd:S000003767|mint:P20459|dip:DIP-2327N - crc64:EC25BAE00F4D1E94 crc64:AF4F1C80303A4E98 figure legend:Supp. Table 5|comment:Amino acid 53 is not a lysine in GCD11 so this crosslink has not been included|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2016/06/01 2016/06/06 rogid:f7BMhuKpbYjQKxE4EmfcVgm6Zv4559292 rogid:9/iGImP9/c8HSYwgmItME27z7lE559292 rigid:InOyJpbjEalkyN/RgBBBhVRbwbE false his tag:c-c|flag tag:c-c|cross linker:249-249|cross linker:249-249|cross linker:249-249|cross linker:249-249 cross linker:67-67|cross linker:175-175 - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P09032 uniprotkb:P32481 intact:EBI-6275|uniprotkb:Q08721|uniprotkb:D6W2W1|ensemblfungi:YOR260W intact:EBI-8924|ensemblfungi:YER025W|uniprotkb:D3DLS4 psi-mi:ei2bg_yeast(display_long)|uniprotkb:GCD1(gene name)|psi-mi:GCD1(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit gamma(gene name synonym)|uniprotkb:GCD complex subunit GCD1(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD1(gene name synonym)|uniprotkb:TIF223(gene name synonym)|uniprotkb:TRA3(gene name synonym)|uniprotkb:YOR260W(locus name) psi-mi:if2g_yeast(display_long)|uniprotkb:YER025W(locus name)|uniprotkb:GCD11(gene name)|psi-mi:GCD11(display_short)|uniprotkb:TIF213(gene name synonym)|uniprotkb:SUI4(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Gordiyenko et al. (2013) pubmed:24852487|imex:IM-25313 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11712766|imex:IM-25313-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014903.1|sgd:S000005786|dip:DIP-1327N|mint:P09032|ensemblfungi:YOR260W(gene)|ensemblfungi:YOR260W_mRNA(transcript)|go:"GO:0002183"(cytoplasmic translational initiation)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:1903574"(negative regulation of cellular response to amino acid starvation)|interpro:IPR011004(Trimeric LpxA-like)|interpro:IPR029044|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731 rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-156827|reactome:R-SCE-381042|reactome:R-SCE-72649|reactome:R-SCE-72695|reactome:R-SCE-72702|reactome:R-SCE-72731|ensemblfungi:YER025W(gene)|ensemblfungi:YER025W_mRNA(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005850"(eukaryotic translation initiation factor 2 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0043614"(multi-eIF complex)|go:"GO:0045903"(positive regulation of translational fidelity)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR015256(Initiation factor eIF2 gamma, C terminal)|interpro:IPR027417|interpro:IPR044127|interpro:IPR044128|rcsb pdb:3J81|rcsb pdb:3JAP|rcsb pdb:3JAQ|rcsb pdb:4ZGN|rcsb pdb:4ZGQ|rcsb pdb:6FYX|rcsb pdb:6FYY|rcsb pdb:6GSM|rcsb pdb:6GSN|refseq:NP_010942.1|sgd:S000000827|mint:P32481|dip:DIP-2561N - crc64:EC25BAE00F4D1E94 crc64:D498AE62BC3E81CD figure legend:Supp. Table 5|comment:Amino acid 53 is not a lysine in GCD11 so this crosslink has not been included|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2016/06/01 2016/06/06 rogid:f7BMhuKpbYjQKxE4EmfcVgm6Zv4559292 rogid:KLaBewFsp1tygK0+hirsBIaMPEI559292 rigid:InOyJpbjEalkyN/RgBBBhVRbwbE false his tag:c-c|flag tag:c-c|cross linker:249-249|cross linker:249-249|cross linker:249-249|cross linker:249-249 cross linker:66-66|cross linker:113-113|cross linker:518-518 - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P09032 uniprotkb:P09064 intact:EBI-6275|uniprotkb:Q08721|uniprotkb:D6W2W1|ensemblfungi:YOR260W intact:EBI-8920|ensemblfungi:YPL237W|uniprotkb:Q6B200|uniprotkb:D6W3D3 psi-mi:ei2bg_yeast(display_long)|uniprotkb:GCD1(gene name)|psi-mi:GCD1(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit gamma(gene name synonym)|uniprotkb:GCD complex subunit GCD1(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD1(gene name synonym)|uniprotkb:TIF223(gene name synonym)|uniprotkb:TRA3(gene name synonym)|uniprotkb:YOR260W(locus name) psi-mi:if2b_yeast(display_long)|uniprotkb:YPL237W(locus name)|uniprotkb:SUI3(gene name)|psi-mi:SUI3(display_short)|uniprotkb:TIF212(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Gordiyenko et al. (2013) pubmed:24852487|imex:IM-25313 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11712766|imex:IM-25313-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014903.1|sgd:S000005786|dip:DIP-1327N|mint:P09032|ensemblfungi:YOR260W(gene)|ensemblfungi:YOR260W_mRNA(transcript)|go:"GO:0002183"(cytoplasmic translational initiation)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:1903574"(negative regulation of cellular response to amino acid starvation)|interpro:IPR011004(Trimeric LpxA-like)|interpro:IPR029044|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731 ensemblfungi:YPL237W(gene)|ensemblfungi:YPL237W_mRNA(transcript)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005850"(eukaryotic translation initiation factor 2 complex)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0043614"(multi-eIF complex)|go:"GO:0046872"(metal ion binding)|interpro:IPR002735(Translation initiation factor IF2/IF5)|interpro:IPR016189(Translation initiation factor IF2/IF5, N-terminal)|interpro:IPR016190(Translation initiation factor IF2/IF5, zinc-binding)|rcsb pdb:3J81|rcsb pdb:3JAP|rcsb pdb:3JAQ|rcsb pdb:6FYX|rcsb pdb:6FYY|rcsb pdb:6GSM|rcsb pdb:6GSN|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72649|refseq:NP_015087.1|sgd:S000006158|reactome:R-SCE-156827|reactome:R-SCE-72695|reactome:R-SCE-72702|reactome:R-SCE-72731|dip:DIP-2310N|reactome:R-SCE-381042 - crc64:EC25BAE00F4D1E94 crc64:34DE9323876CEE95 figure legend:Supp. Table 5|comment:Amino acid 53 is not a lysine in GCD11 so this crosslink has not been included|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2016/06/01 2016/06/06 rogid:f7BMhuKpbYjQKxE4EmfcVgm6Zv4559292 rogid:64fjjpMNrNM6gZW2BzacUQWRC1I559292 rigid:InOyJpbjEalkyN/RgBBBhVRbwbE false his tag:c-c|flag tag:c-c|cross linker:249-249|cross linker:249-249|cross linker:249-249|cross linker:249-249 cross linker:170-170|cross linker:240-240|cross linker:247-247|cross linker:183-183|cross linker:260-260|cross linker:247-247 - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P09032 uniprotkb:P32502 intact:EBI-6275|uniprotkb:Q08721|uniprotkb:D6W2W1|ensemblfungi:YOR260W intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C psi-mi:ei2bg_yeast(display_long)|uniprotkb:GCD1(gene name)|psi-mi:GCD1(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit gamma(gene name synonym)|uniprotkb:GCD complex subunit GCD1(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD1(gene name synonym)|uniprotkb:TIF223(gene name synonym)|uniprotkb:TRA3(gene name synonym)|uniprotkb:YOR260W(locus name) psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name) psi-mi:"MI:0030"(cross-linking study) Gordiyenko et al. (2013) pubmed:24852487|imex:IM-25313 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11712766|imex:IM-25313-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014903.1|sgd:S000005786|dip:DIP-1327N|mint:P09032|ensemblfungi:YOR260W(gene)|ensemblfungi:YOR260W_mRNA(transcript)|go:"GO:0002183"(cytoplasmic translational initiation)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:1903574"(negative regulation of cellular response to amino acid starvation)|interpro:IPR011004(Trimeric LpxA-like)|interpro:IPR029044|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731 refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731 - crc64:EC25BAE00F4D1E94 crc64:A5409FAF1594854C figure legend:Supp. Table 5|comment:Amino acid 53 is not a lysine in GCD11 so this crosslink has not been included|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2016/06/01 2016/06/06 rogid:f7BMhuKpbYjQKxE4EmfcVgm6Zv4559292 rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292 rigid:InOyJpbjEalkyN/RgBBBhVRbwbE false his tag:c-c|flag tag:c-c|cross linker:249-249|cross linker:249-249|cross linker:249-249|cross linker:249-249 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P09032 uniprotkb:P12754 intact:EBI-6275|uniprotkb:Q08721|uniprotkb:D6W2W1|ensemblfungi:YOR260W intact:EBI-6265|uniprotkb:D6VUL5|ensemblfungi:YGR083C psi-mi:ei2bg_yeast(display_long)|uniprotkb:GCD1(gene name)|psi-mi:GCD1(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit gamma(gene name synonym)|uniprotkb:GCD complex subunit GCD1(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD1(gene name synonym)|uniprotkb:TIF223(gene name synonym)|uniprotkb:TRA3(gene name synonym)|uniprotkb:YOR260W(locus name) psi-mi:ei2bd_yeast(display_long)|uniprotkb:GCD2(gene name)|psi-mi:GCD2(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit delta(gene name synonym)|uniprotkb:GCD complex subunit GCD2(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD2(gene name synonym)|uniprotkb:TIF224(gene name synonym)|uniprotkb:YGR083C(locus name) psi-mi:"MI:0030"(cross-linking study) Gordiyenko et al. (2013) pubmed:24852487|imex:IM-25313 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11712766|imex:IM-25313-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014903.1|sgd:S000005786|dip:DIP-1327N|mint:P09032|ensemblfungi:YOR260W(gene)|ensemblfungi:YOR260W_mRNA(transcript)|go:"GO:0002183"(cytoplasmic translational initiation)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:1903574"(negative regulation of cellular response to amino acid starvation)|interpro:IPR011004(Trimeric LpxA-like)|interpro:IPR029044|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731 refseq:NP_011597.1|sgd:S000003315|dip:DIP-2343N|mint:P12754|ensemblfungi:YGR083C(gene)|ensemblfungi:YGR083C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR037171|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731 - crc64:EC25BAE00F4D1E94 crc64:B188457543CE1AAE figure legend:Supp. Table 5|comment:Amino acid 53 is not a lysine in GCD11 so this crosslink has not been included|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2016/06/01 2016/06/06 rogid:f7BMhuKpbYjQKxE4EmfcVgm6Zv4559292 rogid:q04UNg7w1BfegEmJy01O+BDTJno559292 rigid:InOyJpbjEalkyN/RgBBBhVRbwbE false his tag:c-c|flag tag:c-c|cross linker:249-249|cross linker:249-249|cross linker:249-249|cross linker:249-249 cross linker:365-365|cross linker:422-422|cross linker:89-89 - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P09032 uniprotkb:P32501 intact:EBI-6275|uniprotkb:Q08721|uniprotkb:D6W2W1|ensemblfungi:YOR260W intact:EBI-6270|uniprotkb:D6VSJ5|ensemblfungi:YDR211W psi-mi:ei2bg_yeast(display_long)|uniprotkb:GCD1(gene name)|psi-mi:GCD1(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit gamma(gene name synonym)|uniprotkb:GCD complex subunit GCD1(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD1(gene name synonym)|uniprotkb:TIF223(gene name synonym)|uniprotkb:TRA3(gene name synonym)|uniprotkb:YOR260W(locus name) psi-mi:ei2be_yeast(display_long)|uniprotkb:GCD6(gene name)|psi-mi:GCD6(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit epsilon(gene name synonym)|uniprotkb:GCD complex subunit GCD6(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD6(gene name synonym)|uniprotkb:TIF225(gene name synonym)|uniprotkb:YD8142.12(orf name)|uniprotkb:YD8142B.03(orf name)|uniprotkb:YDR211W(locus name) psi-mi:"MI:0030"(cross-linking study) Gordiyenko et al. (2013) pubmed:24852487|imex:IM-25313 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11712766|imex:IM-25313-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014903.1|sgd:S000005786|dip:DIP-1327N|mint:P09032|ensemblfungi:YOR260W(gene)|ensemblfungi:YOR260W_mRNA(transcript)|go:"GO:0002183"(cytoplasmic translational initiation)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:1903574"(negative regulation of cellular response to amino acid starvation)|interpro:IPR011004(Trimeric LpxA-like)|interpro:IPR029044|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731 sgd:S000002619|refseq:NP_010497.3|dip:DIP-2328N|mint:P32501|ensemblfungi:YDR211W(gene)|ensemblfungi:YDR211W_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR001451(Bacterial transferase hexapeptide repeat)|interpro:IPR003307(eIF4-gamma/eIF5/eIF2-epsilon)|interpro:IPR005835(Nucleotidyl transferase)|interpro:IPR011004(Trimeric LpxA-like)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR029044|interpro:IPR035543|interpro:IPR044123|rcsb pdb:1PAQ|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731 - crc64:EC25BAE00F4D1E94 crc64:EFE87F6AE2941619 figure legend:Supp. Table 5|comment:Amino acid 53 is not a lysine in GCD11 so this crosslink has not been included|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2016/06/01 2016/06/06 rogid:f7BMhuKpbYjQKxE4EmfcVgm6Zv4559292 rogid:v70J4JmFrVbw38N8WqOg66aR634559292 rigid:InOyJpbjEalkyN/RgBBBhVRbwbE false his tag:c-c|flag tag:c-c|cross linker:249-249|cross linker:249-249|cross linker:249-249|cross linker:249-249 cross linker:691-691|cross linker:17-17|cross linker:154-154 - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P09032 uniprotkb:P14741 intact:EBI-6275|uniprotkb:Q08721|uniprotkb:D6W2W1|ensemblfungi:YOR260W intact:EBI-6253|uniprotkb:D6VX91|ensemblfungi:YKR026C psi-mi:ei2bg_yeast(display_long)|uniprotkb:GCD1(gene name)|psi-mi:GCD1(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit gamma(gene name synonym)|uniprotkb:GCD complex subunit GCD1(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD1(gene name synonym)|uniprotkb:TIF223(gene name synonym)|uniprotkb:TRA3(gene name synonym)|uniprotkb:YOR260W(locus name) psi-mi:ei2ba_yeast(display_long)|uniprotkb:GCN3(gene name)|psi-mi:GCN3(display_short)|uniprotkb:AAS2(gene name synonym)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit alpha(gene name synonym)|uniprotkb:GCD complex subunit GCN3(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCN3(gene name synonym)|uniprotkb:TIF221(gene name synonym)|uniprotkb:YKR026C(locus name)|uniprotkb:Translational activator GCN3(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Gordiyenko et al. (2013) pubmed:24852487|imex:IM-25313 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11712766|imex:IM-25313-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014903.1|sgd:S000005786|dip:DIP-1327N|mint:P09032|ensemblfungi:YOR260W(gene)|ensemblfungi:YOR260W_mRNA(transcript)|go:"GO:0002183"(cytoplasmic translational initiation)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:1903574"(negative regulation of cellular response to amino acid starvation)|interpro:IPR011004(Trimeric LpxA-like)|interpro:IPR029044|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731 refseq:NP_012951.1|sgd:S000001734|dip:DIP-1328N|mint:P14741|ensemblfungi:YKR026C(gene)|ensemblfungi:YKR026C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|go:"GO:1903833"(positive regulation of cellular response to amino acid starvation)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR037171|interpro:IPR042528|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731 - crc64:EC25BAE00F4D1E94 crc64:8E9A928D6D56E12B figure legend:Supp. Table 5|comment:Amino acid 53 is not a lysine in GCD11 so this crosslink has not been included|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2016/06/01 2016/06/06 rogid:f7BMhuKpbYjQKxE4EmfcVgm6Zv4559292 rogid:Nm+Ahop9EG8SQNZbo6+usIB9SAY559292 rigid:InOyJpbjEalkyN/RgBBBhVRbwbE false his tag:c-c|flag tag:c-c|cross linker:249-249|cross linker:249-249|cross linker:249-249|cross linker:249-249 cross linker:145-145 - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification)