#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P03950	uniprotkb:P07355	intact:EBI-525291|uniprotkb:Q8WXE7|uniprotkb:Q05CV1|uniprotkb:Q53X86|uniprotkb:Q6P5T2|ensembl:ENSP00000336762|ensembl:ENSP00000381077	intact:EBI-352622|uniprotkb:Q567R4|uniprotkb:Q96DD5|intact:EBI-2211824|uniprotkb:Q6N0B3|uniprotkb:Q8TBV2|uniprotkb:Q9UDH8|ensembl:ENSP00000379342|ensembl:ENSP00000387545|ensembl:ENSP00000411352|ensembl:ENSP00000452858|ensembl:ENSP00000452895|ensembl:ENSP00000452981|ensembl:ENSP00000453694|ensembl:ENSP00000453859|ensembl:ENSP00000503447|ensembl:ENSP00000503757|ensembl:ENSP00000503855|ensembl:ENSP00000504035|ensembl:ENSP00000504164	psi-mi:angi_human(display_long)|uniprotkb:Ribonuclease 5(gene name synonym)|uniprotkb:ANG(gene name)|psi-mi:ANG(display_short)|uniprotkb:RNASE5(gene name synonym)	psi-mi:anxa2_human(display_long)|uniprotkb:ANXA2(gene name)|psi-mi:ANXA2(display_short)|uniprotkb:ANX2(gene name synonym)|uniprotkb:ANX2L4(gene name synonym)|uniprotkb:CAL1H(gene name synonym)|uniprotkb:LPC2D(gene name synonym)|uniprotkb:Annexin-2(gene name synonym)|uniprotkb:Annexin II(gene name synonym)|uniprotkb:Lipocortin II(gene name synonym)|uniprotkb:Calpactin I heavy chain(gene name synonym)|uniprotkb:Chromobindin-8(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:Protein I(gene name synonym)|uniprotkb:Placental anticoagulant protein IV(gene name synonym)|uniprotkb:Calpactin-1 heavy chain(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Dutta et al. (2014)	imex:IM-25501|pubmed:24457100	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12512892|imex:IM-25501-21	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001091046.1|refseq:NP_001136.1|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0019732"(antifungal humoral response)|go:"GO:0019843"(rRNA binding)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030426"(growth cone)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0032311"(angiogenin-PRI complex)|go:"GO:0032431"(activation of phospholipase A2 activity)|go:"GO:0042277"(peptide binding)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042592"(homeostatic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045087"(innate immune response)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR001427(Pancreatic ribonuclease)|interpro:IPR023411|interpro:IPR023412|interpro:IPR036816|rcsb pdb:1A4Y|rcsb pdb:1ANG|go:"GO:0016078"(tRNA catabolic process)|go:"GO:0016477"(cell migration)|rcsb pdb:1AWZ|rcsb pdb:1B1E|rcsb pdb:1B1I|rcsb pdb:1B1J|rcsb pdb:1GV7|rcsb pdb:1H0D|rcsb pdb:1H52|rcsb pdb:1H53|rcsb pdb:1HBY|rcsb pdb:1K58|rcsb pdb:1K59|rcsb pdb:1K5A|rcsb pdb:1K5B|rcsb pdb:1UN3|rcsb pdb:1UN4|rcsb pdb:1UN5|rcsb pdb:2ANG|rcsb pdb:4AHD|rcsb pdb:4AHE|rcsb pdb:4AHF|rcsb pdb:4AHG|rcsb pdb:4AHH|rcsb pdb:4AHI|rcsb pdb:4AHJ|rcsb pdb:4AHK|rcsb pdb:4AHL|rcsb pdb:4AHM|rcsb pdb:4AHN|rcsb pdb:4AOH|rcsb pdb:4B36|rcsb pdb:5EOP|rcsb pdb:5EPZ|rcsb pdb:5EQO|rcsb pdb:5M9A|rcsb pdb:5M9C|rcsb pdb:5M9G|rcsb pdb:5M9J|rcsb pdb:5M9M|rcsb pdb:5M9P|rcsb pdb:5M9Q|rcsb pdb:5M9R|rcsb pdb:5M9S|rcsb pdb:5M9T|rcsb pdb:5M9V|reactome:R-HSA-418990|reactome:R-HSA-9708296|ensembl:ENSG00000214274(gene)|ensembl:ENST00000336811(transcript)|ensembl:ENST00000397990(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001878"(response to yeast)|go:"GO:0001890"(placenta development)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0003677"(DNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0004540"(ribonuclease activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005507"(copper ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006651"(diacylglycerol biosynthetic process)|go:"GO:0007154"(cell communication)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0008201"(heparin binding)|go:"GO:0009303"(rRNA transcription)|go:"GO:0009725"(response to hormone)|go:"GO:0015629"(actin cytoskeleton)	refseq:NP_001002857.1|refseq:NP_001002858.1|refseq:NP_001129487.1|refseq:NP_004030.1|refseq:XP_016877579.1|refseq:XP_016877580.1|ensembl:ENSG00000182718(gene)|ensembl:ENST00000396024(transcript)|ensembl:ENST00000421017(transcript)|ensembl:ENST00000451270(transcript)|ensembl:ENST00000557906(transcript)|ensembl:ENST00000558558(transcript)|ensembl:ENST00000559818(transcript)|ensembl:ENST00000559956(transcript)|ensembl:ENST00000560468(transcript)|ensembl:ENST00000677968(transcript)|ensembl:ENST00000678061(transcript)|ensembl:ENST00000678450(transcript)|ensembl:ENST00000678870(transcript)|ensembl:ENST00000679109(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001726"(ruffle)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005938"(cell cortex)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0007589"(body fluid secretion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019834"(phospholipase A2 inhibitor activity)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031340"(positive regulation of vesicle fusion)|go:"GO:0031902"(late endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032804"(negative regulation of low-density lipoprotein particle receptor catabolic process)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035749"(myelin sheath adaxonal region)|go:"GO:0036035"(osteoclast development)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0042730"(fibrinolysis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0044090"(positive regulation of vacuole organization)|go:"GO:0044354"(macropinosome)|go:"GO:0044548"(S100 protein binding)|go:"GO:0044730"(bone sialoprotein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046790"(virion binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0005509"(calcium ion binding)|rcsb pdb:2HYU|rcsb pdb:2HYV|rcsb pdb:2HYW|rcsb pdb:4DRW|rcsb pdb:4FTG|rcsb pdb:4HRH|rcsb pdb:5LPU|rcsb pdb:5LPX|rcsb pdb:5LQ0|rcsb pdb:5LQ2|rcsb pdb:5N7D|rcsb pdb:5N7F|rcsb pdb:5N7G|rcsb pdb:6TWQ|rcsb pdb:6TWU|rcsb pdb:6TWX|rcsb pdb:6TWY|reactome:R-HSA-445355|reactome:R-HSA-6798695|reactome:R-HSA-75205|reactome:R-HSA-8950505|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:1905581"(positive regulation of low-density lipoprotein particle clearance)|go:"GO:1905597"(positive regulation of low-density lipoprotein particle receptor binding)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|go:"GO:1905602"(positive regulation of receptor-mediated endocytosis involved in cholesterol transport)|go:"GO:1990665"(AnxA2-p11 complex)|go:"GO:1990667"(PCSK9-AnxA2 complex)|interpro:IPR001464(Annexin)|interpro:IPR002389(Annexin, type II)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P07355|rcsb pdb:1W7B|rcsb pdb:1XJL|go:"GO:0097066"(response to thyroid hormone)	-	-	-	figure legend:5C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-t47d-a18)|taxid:9606(ER- and PR-positive hormone-responsive clone of t47d)	-	2016/07/19	2016/08/24	rogid:CSOTublnrV3DIGJfeyCfT14p8m89606	rogid:jcB4Dt0LFv8YaBUnC2BSTCshveg9606	rigid:oOtMjSYR+6rpqn+rDLfskQBRRZs	false	biotin tag:?-?	biotin tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P03950	uniprotkb:P60903	intact:EBI-525291|uniprotkb:Q8WXE7|uniprotkb:Q05CV1|uniprotkb:Q53X86|uniprotkb:Q6P5T2|ensembl:ENSP00000336762|ensembl:ENSP00000381077	intact:EBI-717048|uniprotkb:P08206|uniprotkb:Q5T1C5|uniprotkb:A8K4V8|ensembl:ENSP00000357799|ensembl:ENSP00000357801	psi-mi:angi_human(display_long)|uniprotkb:Ribonuclease 5(gene name synonym)|uniprotkb:ANG(gene name)|psi-mi:ANG(display_short)|uniprotkb:RNASE5(gene name synonym)	psi-mi:s10aa_human(display_long)|uniprotkb:S100 calcium-binding protein A10(gene name synonym)|uniprotkb:Calpactin-1 light chain(gene name synonym)|uniprotkb:Calpactin I light chain(gene name synonym)|uniprotkb:p10 protein(gene name synonym)|uniprotkb:p11(gene name synonym)|uniprotkb:Cellular ligand of annexin II(gene name synonym)|uniprotkb:S100A10(gene name)|psi-mi:S100A10(display_short)|uniprotkb:ANX2LG(gene name synonym)|uniprotkb:CAL1L(gene name synonym)|uniprotkb:CLP11(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Dutta et al. (2014)	imex:IM-25501|pubmed:24457100	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12512892|imex:IM-25501-21	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001091046.1|refseq:NP_001136.1|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0019732"(antifungal humoral response)|go:"GO:0019843"(rRNA binding)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030426"(growth cone)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0032311"(angiogenin-PRI complex)|go:"GO:0032431"(activation of phospholipase A2 activity)|go:"GO:0042277"(peptide binding)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042592"(homeostatic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045087"(innate immune response)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR001427(Pancreatic ribonuclease)|interpro:IPR023411|interpro:IPR023412|interpro:IPR036816|rcsb pdb:1A4Y|rcsb pdb:1ANG|go:"GO:0016078"(tRNA catabolic process)|go:"GO:0016477"(cell migration)|rcsb pdb:1AWZ|rcsb pdb:1B1E|rcsb pdb:1B1I|rcsb pdb:1B1J|rcsb pdb:1GV7|rcsb pdb:1H0D|rcsb pdb:1H52|rcsb pdb:1H53|rcsb pdb:1HBY|rcsb pdb:1K58|rcsb pdb:1K59|rcsb pdb:1K5A|rcsb pdb:1K5B|rcsb pdb:1UN3|rcsb pdb:1UN4|rcsb pdb:1UN5|rcsb pdb:2ANG|rcsb pdb:4AHD|rcsb pdb:4AHE|rcsb pdb:4AHF|rcsb pdb:4AHG|rcsb pdb:4AHH|rcsb pdb:4AHI|rcsb pdb:4AHJ|rcsb pdb:4AHK|rcsb pdb:4AHL|rcsb pdb:4AHM|rcsb pdb:4AHN|rcsb pdb:4AOH|rcsb pdb:4B36|rcsb pdb:5EOP|rcsb pdb:5EPZ|rcsb pdb:5EQO|rcsb pdb:5M9A|rcsb pdb:5M9C|rcsb pdb:5M9G|rcsb pdb:5M9J|rcsb pdb:5M9M|rcsb pdb:5M9P|rcsb pdb:5M9Q|rcsb pdb:5M9R|rcsb pdb:5M9S|rcsb pdb:5M9T|rcsb pdb:5M9V|reactome:R-HSA-418990|reactome:R-HSA-9708296|ensembl:ENSG00000214274(gene)|ensembl:ENST00000336811(transcript)|ensembl:ENST00000397990(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001878"(response to yeast)|go:"GO:0001890"(placenta development)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0003677"(DNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0004540"(ribonuclease activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005507"(copper ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006651"(diacylglycerol biosynthetic process)|go:"GO:0007154"(cell communication)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0008201"(heparin binding)|go:"GO:0009303"(rRNA transcription)|go:"GO:0009725"(response to hormone)|go:"GO:0015629"(actin cytoskeleton)	refseq:NP_002957.1|ensembl:ENSG00000197747(gene)|ensembl:ENST00000368809(transcript)|ensembl:ENST00000368811(transcript)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0005576"(extracellular region)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0042493"|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1990665"(AnxA2-p11 complex)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR028476|rcsb pdb:1A4P|rcsb pdb:1BT6|rcsb pdb:4DRW|rcsb pdb:4FTG|rcsb pdb:4HRE|rcsb pdb:4HRG|rcsb pdb:4HRH|reactome:R-HSA-75205	-	-	-	figure legend:5C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-t47d-a18)|taxid:9606(ER- and PR-positive hormone-responsive clone of t47d)	-	2016/07/19	2016/08/24	rogid:CSOTublnrV3DIGJfeyCfT14p8m89606	rogid:WlxwW4qaHp6tcyEAYvQ2ut9SyRA9606	rigid:oOtMjSYR+6rpqn+rDLfskQBRRZs	false	biotin tag:?-?	biotin tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P03950	uniprotkb:Q03405	intact:EBI-525291|uniprotkb:Q8WXE7|uniprotkb:Q05CV1|uniprotkb:Q53X86|uniprotkb:Q6P5T2|ensembl:ENSP00000336762|ensembl:ENSP00000381077	intact:EBI-716505|uniprotkb:Q12876|uniprotkb:Q15845|uniprotkb:Q16887|uniprotkb:Q6IB52|uniprotkb:Q9BWT0|uniprotkb:Q9NYC8|uniprotkb:Q9UD69|uniprotkb:Q9UEA6|uniprotkb:Q9UM92|uniprotkb:Q9UMV0|uniprotkb:A8K409|ensembl:ENSP00000339328	psi-mi:angi_human(display_long)|uniprotkb:Ribonuclease 5(gene name synonym)|uniprotkb:ANG(gene name)|psi-mi:ANG(display_short)|uniprotkb:RNASE5(gene name synonym)	psi-mi:upar_human(display_long)|uniprotkb:Monocyte activation antigen Mo3(gene name synonym)|uniprotkb:PLAUR(gene name)|psi-mi:PLAUR(display_short)|uniprotkb:MO3(gene name synonym)|uniprotkb:UPAR(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Dutta et al. (2014)	imex:IM-25501|pubmed:24457100	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12512994|imex:IM-25501-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001091046.1|refseq:NP_001136.1|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0019732"(antifungal humoral response)|go:"GO:0019843"(rRNA binding)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030426"(growth cone)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0032311"(angiogenin-PRI complex)|go:"GO:0032431"(activation of phospholipase A2 activity)|go:"GO:0042277"(peptide binding)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042592"(homeostatic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045087"(innate immune response)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR001427(Pancreatic ribonuclease)|interpro:IPR023411|interpro:IPR023412|interpro:IPR036816|rcsb pdb:1A4Y|rcsb pdb:1ANG|go:"GO:0016078"(tRNA catabolic process)|go:"GO:0016477"(cell migration)|rcsb pdb:1AWZ|rcsb pdb:1B1E|rcsb pdb:1B1I|rcsb pdb:1B1J|rcsb pdb:1GV7|rcsb pdb:1H0D|rcsb pdb:1H52|rcsb pdb:1H53|rcsb pdb:1HBY|rcsb pdb:1K58|rcsb pdb:1K59|rcsb pdb:1K5A|rcsb pdb:1K5B|rcsb pdb:1UN3|rcsb pdb:1UN4|rcsb pdb:1UN5|rcsb pdb:2ANG|rcsb pdb:4AHD|rcsb pdb:4AHE|rcsb pdb:4AHF|rcsb pdb:4AHG|rcsb pdb:4AHH|rcsb pdb:4AHI|rcsb pdb:4AHJ|rcsb pdb:4AHK|rcsb pdb:4AHL|rcsb pdb:4AHM|rcsb pdb:4AHN|rcsb pdb:4AOH|rcsb pdb:4B36|rcsb pdb:5EOP|rcsb pdb:5EPZ|rcsb pdb:5EQO|rcsb pdb:5M9A|rcsb pdb:5M9C|rcsb pdb:5M9G|rcsb pdb:5M9J|rcsb pdb:5M9M|rcsb pdb:5M9P|rcsb pdb:5M9Q|rcsb pdb:5M9R|rcsb pdb:5M9S|rcsb pdb:5M9T|rcsb pdb:5M9V|reactome:R-HSA-418990|reactome:R-HSA-9708296|ensembl:ENSG00000214274(gene)|ensembl:ENST00000336811(transcript)|ensembl:ENST00000397990(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001878"(response to yeast)|go:"GO:0001890"(placenta development)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0003677"(DNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0004540"(ribonuclease activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005507"(copper ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006651"(diacylglycerol biosynthetic process)|go:"GO:0007154"(cell communication)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0008201"(heparin binding)|go:"GO:0009303"(rRNA transcription)|go:"GO:0009725"(response to hormone)|go:"GO:0015629"(actin cytoskeleton)	refseq:NP_001005376.1|refseq:NP_001005377.1|refseq:NP_002650.1|reactome:R-HSA-162791|reactome:R-HSA-6798695|reactome:R-HSA-75205|rcsb pdb:4QTI|ensembl:ENSG00000011422(gene)|ensembl:ENST00000340093(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006935"(chemotaxis)|go:"GO:0007165"(signal transduction)|go:"GO:0007596"(blood coagulation)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030162"(regulation of proteolysis)|go:"GO:0030377"(urokinase plasminogen activator receptor activity)|go:"GO:0034112"(positive regulation of homotypic cell-cell adhesion)|go:"GO:0035579"(specific granule membrane)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042995"(cell projection)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|go:"GO:0031225"(anchored component of membrane)|go:"GO:2001268"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|interpro:IPR018363|interpro:IPR033084|rcsb pdb:1YWH|rcsb pdb:2FD6|rcsb pdb:2I9B|rcsb pdb:3BT1|rcsb pdb:3BT2|rcsb pdb:3U73|rcsb pdb:3U74|rcsb pdb:4K24|refseq:NP_001287966.1|dip:DIP-137N	-	-	-	figure legend:6Ai|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-t47d-a18)|taxid:9606(ER- and PR-positive hormone-responsive clone of t47d)	-	2016/07/19	2016/08/24	rogid:CSOTublnrV3DIGJfeyCfT14p8m89606	rogid:faxxSUpKpPAaAlPpUpvg2NG4DOA9606	rigid:jUL/NxyXqMLsqRAoKDrPAvEw5ZQ	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P03950	uniprotkb:P07355	intact:EBI-525291|uniprotkb:Q8WXE7|uniprotkb:Q05CV1|uniprotkb:Q53X86|uniprotkb:Q6P5T2|ensembl:ENSP00000336762|ensembl:ENSP00000381077	intact:EBI-352622|uniprotkb:Q567R4|uniprotkb:Q96DD5|intact:EBI-2211824|uniprotkb:Q6N0B3|uniprotkb:Q8TBV2|uniprotkb:Q9UDH8|ensembl:ENSP00000379342|ensembl:ENSP00000387545|ensembl:ENSP00000411352|ensembl:ENSP00000452858|ensembl:ENSP00000452895|ensembl:ENSP00000452981|ensembl:ENSP00000453694|ensembl:ENSP00000453859|ensembl:ENSP00000503447|ensembl:ENSP00000503757|ensembl:ENSP00000503855|ensembl:ENSP00000504035|ensembl:ENSP00000504164	psi-mi:angi_human(display_long)|uniprotkb:Ribonuclease 5(gene name synonym)|uniprotkb:ANG(gene name)|psi-mi:ANG(display_short)|uniprotkb:RNASE5(gene name synonym)	psi-mi:anxa2_human(display_long)|uniprotkb:ANXA2(gene name)|psi-mi:ANXA2(display_short)|uniprotkb:ANX2(gene name synonym)|uniprotkb:ANX2L4(gene name synonym)|uniprotkb:CAL1H(gene name synonym)|uniprotkb:LPC2D(gene name synonym)|uniprotkb:Annexin-2(gene name synonym)|uniprotkb:Annexin II(gene name synonym)|uniprotkb:Lipocortin II(gene name synonym)|uniprotkb:Calpactin I heavy chain(gene name synonym)|uniprotkb:Chromobindin-8(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:Protein I(gene name synonym)|uniprotkb:Placental anticoagulant protein IV(gene name synonym)|uniprotkb:Calpactin-1 heavy chain(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Dutta et al. (2014)	imex:IM-25501|pubmed:24457100	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12512994|imex:IM-25501-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001091046.1|refseq:NP_001136.1|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0019732"(antifungal humoral response)|go:"GO:0019843"(rRNA binding)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030426"(growth cone)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0032311"(angiogenin-PRI complex)|go:"GO:0032431"(activation of phospholipase A2 activity)|go:"GO:0042277"(peptide binding)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042592"(homeostatic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045087"(innate immune response)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR001427(Pancreatic ribonuclease)|interpro:IPR023411|interpro:IPR023412|interpro:IPR036816|rcsb pdb:1A4Y|rcsb pdb:1ANG|go:"GO:0016078"(tRNA catabolic process)|go:"GO:0016477"(cell migration)|rcsb pdb:1AWZ|rcsb pdb:1B1E|rcsb pdb:1B1I|rcsb pdb:1B1J|rcsb pdb:1GV7|rcsb pdb:1H0D|rcsb pdb:1H52|rcsb pdb:1H53|rcsb pdb:1HBY|rcsb pdb:1K58|rcsb pdb:1K59|rcsb pdb:1K5A|rcsb pdb:1K5B|rcsb pdb:1UN3|rcsb pdb:1UN4|rcsb pdb:1UN5|rcsb pdb:2ANG|rcsb pdb:4AHD|rcsb pdb:4AHE|rcsb pdb:4AHF|rcsb pdb:4AHG|rcsb pdb:4AHH|rcsb pdb:4AHI|rcsb pdb:4AHJ|rcsb pdb:4AHK|rcsb pdb:4AHL|rcsb pdb:4AHM|rcsb pdb:4AHN|rcsb pdb:4AOH|rcsb pdb:4B36|rcsb pdb:5EOP|rcsb pdb:5EPZ|rcsb pdb:5EQO|rcsb pdb:5M9A|rcsb pdb:5M9C|rcsb pdb:5M9G|rcsb pdb:5M9J|rcsb pdb:5M9M|rcsb pdb:5M9P|rcsb pdb:5M9Q|rcsb pdb:5M9R|rcsb pdb:5M9S|rcsb pdb:5M9T|rcsb pdb:5M9V|reactome:R-HSA-418990|reactome:R-HSA-9708296|ensembl:ENSG00000214274(gene)|ensembl:ENST00000336811(transcript)|ensembl:ENST00000397990(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001878"(response to yeast)|go:"GO:0001890"(placenta development)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0003677"(DNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0004540"(ribonuclease activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005507"(copper ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006651"(diacylglycerol biosynthetic process)|go:"GO:0007154"(cell communication)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0008201"(heparin binding)|go:"GO:0009303"(rRNA transcription)|go:"GO:0009725"(response to hormone)|go:"GO:0015629"(actin cytoskeleton)	refseq:NP_001002857.1|refseq:NP_001002858.1|refseq:NP_001129487.1|refseq:NP_004030.1|refseq:XP_016877579.1|refseq:XP_016877580.1|ensembl:ENSG00000182718(gene)|ensembl:ENST00000396024(transcript)|ensembl:ENST00000421017(transcript)|ensembl:ENST00000451270(transcript)|ensembl:ENST00000557906(transcript)|ensembl:ENST00000558558(transcript)|ensembl:ENST00000559818(transcript)|ensembl:ENST00000559956(transcript)|ensembl:ENST00000560468(transcript)|ensembl:ENST00000677968(transcript)|ensembl:ENST00000678061(transcript)|ensembl:ENST00000678450(transcript)|ensembl:ENST00000678870(transcript)|ensembl:ENST00000679109(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001726"(ruffle)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005938"(cell cortex)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0007589"(body fluid secretion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019834"(phospholipase A2 inhibitor activity)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031340"(positive regulation of vesicle fusion)|go:"GO:0031902"(late endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032804"(negative regulation of low-density lipoprotein particle receptor catabolic process)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035749"(myelin sheath adaxonal region)|go:"GO:0036035"(osteoclast development)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0042730"(fibrinolysis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0044090"(positive regulation of vacuole organization)|go:"GO:0044354"(macropinosome)|go:"GO:0044548"(S100 protein binding)|go:"GO:0044730"(bone sialoprotein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046790"(virion binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0005509"(calcium ion binding)|rcsb pdb:2HYU|rcsb pdb:2HYV|rcsb pdb:2HYW|rcsb pdb:4DRW|rcsb pdb:4FTG|rcsb pdb:4HRH|rcsb pdb:5LPU|rcsb pdb:5LPX|rcsb pdb:5LQ0|rcsb pdb:5LQ2|rcsb pdb:5N7D|rcsb pdb:5N7F|rcsb pdb:5N7G|rcsb pdb:6TWQ|rcsb pdb:6TWU|rcsb pdb:6TWX|rcsb pdb:6TWY|reactome:R-HSA-445355|reactome:R-HSA-6798695|reactome:R-HSA-75205|reactome:R-HSA-8950505|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:1905581"(positive regulation of low-density lipoprotein particle clearance)|go:"GO:1905597"(positive regulation of low-density lipoprotein particle receptor binding)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|go:"GO:1905602"(positive regulation of receptor-mediated endocytosis involved in cholesterol transport)|go:"GO:1990665"(AnxA2-p11 complex)|go:"GO:1990667"(PCSK9-AnxA2 complex)|interpro:IPR001464(Annexin)|interpro:IPR002389(Annexin, type II)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P07355|rcsb pdb:1W7B|rcsb pdb:1XJL|go:"GO:0097066"(response to thyroid hormone)	-	-	-	figure legend:6Ai|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-t47d-a18)|taxid:9606(ER- and PR-positive hormone-responsive clone of t47d)	-	2016/07/19	2016/08/24	rogid:CSOTublnrV3DIGJfeyCfT14p8m89606	rogid:jcB4Dt0LFv8YaBUnC2BSTCshveg9606	rigid:jUL/NxyXqMLsqRAoKDrPAvEw5ZQ	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P03950	uniprotkb:P60903	intact:EBI-525291|uniprotkb:Q8WXE7|uniprotkb:Q05CV1|uniprotkb:Q53X86|uniprotkb:Q6P5T2|ensembl:ENSP00000336762|ensembl:ENSP00000381077	intact:EBI-717048|uniprotkb:P08206|uniprotkb:Q5T1C5|uniprotkb:A8K4V8|ensembl:ENSP00000357799|ensembl:ENSP00000357801	psi-mi:angi_human(display_long)|uniprotkb:Ribonuclease 5(gene name synonym)|uniprotkb:ANG(gene name)|psi-mi:ANG(display_short)|uniprotkb:RNASE5(gene name synonym)	psi-mi:s10aa_human(display_long)|uniprotkb:S100 calcium-binding protein A10(gene name synonym)|uniprotkb:Calpactin-1 light chain(gene name synonym)|uniprotkb:Calpactin I light chain(gene name synonym)|uniprotkb:p10 protein(gene name synonym)|uniprotkb:p11(gene name synonym)|uniprotkb:Cellular ligand of annexin II(gene name synonym)|uniprotkb:S100A10(gene name)|psi-mi:S100A10(display_short)|uniprotkb:ANX2LG(gene name synonym)|uniprotkb:CAL1L(gene name synonym)|uniprotkb:CLP11(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Dutta et al. (2014)	imex:IM-25501|pubmed:24457100	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12512994|imex:IM-25501-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001091046.1|refseq:NP_001136.1|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0019732"(antifungal humoral response)|go:"GO:0019843"(rRNA binding)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030426"(growth cone)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0032311"(angiogenin-PRI complex)|go:"GO:0032431"(activation of phospholipase A2 activity)|go:"GO:0042277"(peptide binding)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042592"(homeostatic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045087"(innate immune response)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR001427(Pancreatic ribonuclease)|interpro:IPR023411|interpro:IPR023412|interpro:IPR036816|rcsb pdb:1A4Y|rcsb pdb:1ANG|go:"GO:0016078"(tRNA catabolic process)|go:"GO:0016477"(cell migration)|rcsb pdb:1AWZ|rcsb pdb:1B1E|rcsb pdb:1B1I|rcsb pdb:1B1J|rcsb pdb:1GV7|rcsb pdb:1H0D|rcsb pdb:1H52|rcsb pdb:1H53|rcsb pdb:1HBY|rcsb pdb:1K58|rcsb pdb:1K59|rcsb pdb:1K5A|rcsb pdb:1K5B|rcsb pdb:1UN3|rcsb pdb:1UN4|rcsb pdb:1UN5|rcsb pdb:2ANG|rcsb pdb:4AHD|rcsb pdb:4AHE|rcsb pdb:4AHF|rcsb pdb:4AHG|rcsb pdb:4AHH|rcsb pdb:4AHI|rcsb pdb:4AHJ|rcsb pdb:4AHK|rcsb pdb:4AHL|rcsb pdb:4AHM|rcsb pdb:4AHN|rcsb pdb:4AOH|rcsb pdb:4B36|rcsb pdb:5EOP|rcsb pdb:5EPZ|rcsb pdb:5EQO|rcsb pdb:5M9A|rcsb pdb:5M9C|rcsb pdb:5M9G|rcsb pdb:5M9J|rcsb pdb:5M9M|rcsb pdb:5M9P|rcsb pdb:5M9Q|rcsb pdb:5M9R|rcsb pdb:5M9S|rcsb pdb:5M9T|rcsb pdb:5M9V|reactome:R-HSA-418990|reactome:R-HSA-9708296|ensembl:ENSG00000214274(gene)|ensembl:ENST00000336811(transcript)|ensembl:ENST00000397990(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001878"(response to yeast)|go:"GO:0001890"(placenta development)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0003677"(DNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0004540"(ribonuclease activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005507"(copper ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006651"(diacylglycerol biosynthetic process)|go:"GO:0007154"(cell communication)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0008201"(heparin binding)|go:"GO:0009303"(rRNA transcription)|go:"GO:0009725"(response to hormone)|go:"GO:0015629"(actin cytoskeleton)	refseq:NP_002957.1|ensembl:ENSG00000197747(gene)|ensembl:ENST00000368809(transcript)|ensembl:ENST00000368811(transcript)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0005576"(extracellular region)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0042493"|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1990665"(AnxA2-p11 complex)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR028476|rcsb pdb:1A4P|rcsb pdb:1BT6|rcsb pdb:4DRW|rcsb pdb:4FTG|rcsb pdb:4HRE|rcsb pdb:4HRG|rcsb pdb:4HRH|reactome:R-HSA-75205	-	-	-	figure legend:6Ai|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-t47d-a18)|taxid:9606(ER- and PR-positive hormone-responsive clone of t47d)	-	2016/07/19	2016/08/24	rogid:CSOTublnrV3DIGJfeyCfT14p8m89606	rogid:WlxwW4qaHp6tcyEAYvQ2ut9SyRA9606	rigid:jUL/NxyXqMLsqRAoKDrPAvEw5ZQ	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P60903	uniprotkb:P07355	intact:EBI-717048|uniprotkb:P08206|uniprotkb:Q5T1C5|uniprotkb:A8K4V8|ensembl:ENSP00000357799|ensembl:ENSP00000357801	intact:EBI-352622|uniprotkb:Q567R4|uniprotkb:Q96DD5|intact:EBI-2211824|uniprotkb:Q6N0B3|uniprotkb:Q8TBV2|uniprotkb:Q9UDH8|ensembl:ENSP00000379342|ensembl:ENSP00000387545|ensembl:ENSP00000411352|ensembl:ENSP00000452858|ensembl:ENSP00000452895|ensembl:ENSP00000452981|ensembl:ENSP00000453694|ensembl:ENSP00000453859|ensembl:ENSP00000503447|ensembl:ENSP00000503757|ensembl:ENSP00000503855|ensembl:ENSP00000504035|ensembl:ENSP00000504164	psi-mi:s10aa_human(display_long)|uniprotkb:S100 calcium-binding protein A10(gene name synonym)|uniprotkb:Calpactin-1 light chain(gene name synonym)|uniprotkb:Calpactin I light chain(gene name synonym)|uniprotkb:p10 protein(gene name synonym)|uniprotkb:p11(gene name synonym)|uniprotkb:Cellular ligand of annexin II(gene name synonym)|uniprotkb:S100A10(gene name)|psi-mi:S100A10(display_short)|uniprotkb:ANX2LG(gene name synonym)|uniprotkb:CAL1L(gene name synonym)|uniprotkb:CLP11(gene name synonym)	psi-mi:anxa2_human(display_long)|uniprotkb:ANXA2(gene name)|psi-mi:ANXA2(display_short)|uniprotkb:ANX2(gene name synonym)|uniprotkb:ANX2L4(gene name synonym)|uniprotkb:CAL1H(gene name synonym)|uniprotkb:LPC2D(gene name synonym)|uniprotkb:Annexin-2(gene name synonym)|uniprotkb:Annexin II(gene name synonym)|uniprotkb:Lipocortin II(gene name synonym)|uniprotkb:Calpactin I heavy chain(gene name synonym)|uniprotkb:Chromobindin-8(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:Protein I(gene name synonym)|uniprotkb:Placental anticoagulant protein IV(gene name synonym)|uniprotkb:Calpactin-1 heavy chain(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Dutta et al. (2014)	imex:IM-25501|pubmed:24457100	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12513019|imex:IM-25501-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002957.1|ensembl:ENSG00000197747(gene)|ensembl:ENST00000368809(transcript)|ensembl:ENST00000368811(transcript)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0005576"(extracellular region)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0042493"|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1990665"(AnxA2-p11 complex)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR028476|rcsb pdb:1A4P|rcsb pdb:1BT6|rcsb pdb:4DRW|rcsb pdb:4FTG|rcsb pdb:4HRE|rcsb pdb:4HRG|rcsb pdb:4HRH|reactome:R-HSA-75205	refseq:NP_001002857.1|refseq:NP_001002858.1|refseq:NP_001129487.1|refseq:NP_004030.1|refseq:XP_016877579.1|refseq:XP_016877580.1|ensembl:ENSG00000182718(gene)|ensembl:ENST00000396024(transcript)|ensembl:ENST00000421017(transcript)|ensembl:ENST00000451270(transcript)|ensembl:ENST00000557906(transcript)|ensembl:ENST00000558558(transcript)|ensembl:ENST00000559818(transcript)|ensembl:ENST00000559956(transcript)|ensembl:ENST00000560468(transcript)|ensembl:ENST00000677968(transcript)|ensembl:ENST00000678061(transcript)|ensembl:ENST00000678450(transcript)|ensembl:ENST00000678870(transcript)|ensembl:ENST00000679109(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001726"(ruffle)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005938"(cell cortex)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0007589"(body fluid secretion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019834"(phospholipase A2 inhibitor activity)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031340"(positive regulation of vesicle fusion)|go:"GO:0031902"(late endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032804"(negative regulation of low-density lipoprotein particle receptor catabolic process)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035749"(myelin sheath adaxonal region)|go:"GO:0036035"(osteoclast development)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0042730"(fibrinolysis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0044090"(positive regulation of vacuole organization)|go:"GO:0044354"(macropinosome)|go:"GO:0044548"(S100 protein binding)|go:"GO:0044730"(bone sialoprotein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046790"(virion binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0005509"(calcium ion binding)|rcsb pdb:2HYU|rcsb pdb:2HYV|rcsb pdb:2HYW|rcsb pdb:4DRW|rcsb pdb:4FTG|rcsb pdb:4HRH|rcsb pdb:5LPU|rcsb pdb:5LPX|rcsb pdb:5LQ0|rcsb pdb:5LQ2|rcsb pdb:5N7D|rcsb pdb:5N7F|rcsb pdb:5N7G|rcsb pdb:6TWQ|rcsb pdb:6TWU|rcsb pdb:6TWX|rcsb pdb:6TWY|reactome:R-HSA-445355|reactome:R-HSA-6798695|reactome:R-HSA-75205|reactome:R-HSA-8950505|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:1905581"(positive regulation of low-density lipoprotein particle clearance)|go:"GO:1905597"(positive regulation of low-density lipoprotein particle receptor binding)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|go:"GO:1905602"(positive regulation of receptor-mediated endocytosis involved in cholesterol transport)|go:"GO:1990665"(AnxA2-p11 complex)|go:"GO:1990667"(PCSK9-AnxA2 complex)|interpro:IPR001464(Annexin)|interpro:IPR002389(Annexin, type II)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P07355|rcsb pdb:1W7B|rcsb pdb:1XJL|go:"GO:0097066"(response to thyroid hormone)	-	-	-	figure legend:6Aii|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-t47d-a18)|taxid:9606(ER- and PR-positive hormone-responsive clone of t47d)	-	2016/07/19	2016/08/24	rogid:WlxwW4qaHp6tcyEAYvQ2ut9SyRA9606	rogid:jcB4Dt0LFv8YaBUnC2BSTCshveg9606	rigid:oOtMjSYR+6rpqn+rDLfskQBRRZs	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P60903	uniprotkb:P03950	intact:EBI-717048|uniprotkb:P08206|uniprotkb:Q5T1C5|uniprotkb:A8K4V8|ensembl:ENSP00000357799|ensembl:ENSP00000357801	intact:EBI-525291|uniprotkb:Q8WXE7|uniprotkb:Q05CV1|uniprotkb:Q53X86|uniprotkb:Q6P5T2|ensembl:ENSP00000336762|ensembl:ENSP00000381077	psi-mi:s10aa_human(display_long)|uniprotkb:S100 calcium-binding protein A10(gene name synonym)|uniprotkb:Calpactin-1 light chain(gene name synonym)|uniprotkb:Calpactin I light chain(gene name synonym)|uniprotkb:p10 protein(gene name synonym)|uniprotkb:p11(gene name synonym)|uniprotkb:Cellular ligand of annexin II(gene name synonym)|uniprotkb:S100A10(gene name)|psi-mi:S100A10(display_short)|uniprotkb:ANX2LG(gene name synonym)|uniprotkb:CAL1L(gene name synonym)|uniprotkb:CLP11(gene name synonym)	psi-mi:angi_human(display_long)|uniprotkb:Ribonuclease 5(gene name synonym)|uniprotkb:ANG(gene name)|psi-mi:ANG(display_short)|uniprotkb:RNASE5(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Dutta et al. (2014)	imex:IM-25501|pubmed:24457100	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12513019|imex:IM-25501-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002957.1|ensembl:ENSG00000197747(gene)|ensembl:ENST00000368809(transcript)|ensembl:ENST00000368811(transcript)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0005576"(extracellular region)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0042493"|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1990665"(AnxA2-p11 complex)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR028476|rcsb pdb:1A4P|rcsb pdb:1BT6|rcsb pdb:4DRW|rcsb pdb:4FTG|rcsb pdb:4HRE|rcsb pdb:4HRG|rcsb pdb:4HRH|reactome:R-HSA-75205	refseq:NP_001091046.1|refseq:NP_001136.1|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0019732"(antifungal humoral response)|go:"GO:0019843"(rRNA binding)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030426"(growth cone)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0032311"(angiogenin-PRI complex)|go:"GO:0032431"(activation of phospholipase A2 activity)|go:"GO:0042277"(peptide binding)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042592"(homeostatic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045087"(innate immune response)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR001427(Pancreatic ribonuclease)|interpro:IPR023411|interpro:IPR023412|interpro:IPR036816|rcsb pdb:1A4Y|rcsb pdb:1ANG|go:"GO:0016078"(tRNA catabolic process)|go:"GO:0016477"(cell migration)|rcsb pdb:1AWZ|rcsb pdb:1B1E|rcsb pdb:1B1I|rcsb pdb:1B1J|rcsb pdb:1GV7|rcsb pdb:1H0D|rcsb pdb:1H52|rcsb pdb:1H53|rcsb pdb:1HBY|rcsb pdb:1K58|rcsb pdb:1K59|rcsb pdb:1K5A|rcsb pdb:1K5B|rcsb pdb:1UN3|rcsb pdb:1UN4|rcsb pdb:1UN5|rcsb pdb:2ANG|rcsb pdb:4AHD|rcsb pdb:4AHE|rcsb pdb:4AHF|rcsb pdb:4AHG|rcsb pdb:4AHH|rcsb pdb:4AHI|rcsb pdb:4AHJ|rcsb pdb:4AHK|rcsb pdb:4AHL|rcsb pdb:4AHM|rcsb pdb:4AHN|rcsb pdb:4AOH|rcsb pdb:4B36|rcsb pdb:5EOP|rcsb pdb:5EPZ|rcsb pdb:5EQO|rcsb pdb:5M9A|rcsb pdb:5M9C|rcsb pdb:5M9G|rcsb pdb:5M9J|rcsb pdb:5M9M|rcsb pdb:5M9P|rcsb pdb:5M9Q|rcsb pdb:5M9R|rcsb pdb:5M9S|rcsb pdb:5M9T|rcsb pdb:5M9V|reactome:R-HSA-418990|reactome:R-HSA-9708296|ensembl:ENSG00000214274(gene)|ensembl:ENST00000336811(transcript)|ensembl:ENST00000397990(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001878"(response to yeast)|go:"GO:0001890"(placenta development)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0003677"(DNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0004540"(ribonuclease activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005507"(copper ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006651"(diacylglycerol biosynthetic process)|go:"GO:0007154"(cell communication)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0008201"(heparin binding)|go:"GO:0009303"(rRNA transcription)|go:"GO:0009725"(response to hormone)|go:"GO:0015629"(actin cytoskeleton)	-	-	-	figure legend:6Aii|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-t47d-a18)|taxid:9606(ER- and PR-positive hormone-responsive clone of t47d)	-	2016/07/19	2016/08/24	rogid:WlxwW4qaHp6tcyEAYvQ2ut9SyRA9606	rogid:CSOTublnrV3DIGJfeyCfT14p8m89606	rigid:oOtMjSYR+6rpqn+rDLfskQBRRZs	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P07355	uniprotkb:P60903	intact:EBI-352622|uniprotkb:Q567R4|uniprotkb:Q96DD5|intact:EBI-2211824|uniprotkb:Q6N0B3|uniprotkb:Q8TBV2|uniprotkb:Q9UDH8|ensembl:ENSP00000379342|ensembl:ENSP00000387545|ensembl:ENSP00000411352|ensembl:ENSP00000452858|ensembl:ENSP00000452895|ensembl:ENSP00000452981|ensembl:ENSP00000453694|ensembl:ENSP00000453859|ensembl:ENSP00000503447|ensembl:ENSP00000503757|ensembl:ENSP00000503855|ensembl:ENSP00000504035|ensembl:ENSP00000504164	intact:EBI-717048|uniprotkb:P08206|uniprotkb:Q5T1C5|uniprotkb:A8K4V8|ensembl:ENSP00000357799|ensembl:ENSP00000357801	psi-mi:anxa2_human(display_long)|uniprotkb:ANXA2(gene name)|psi-mi:ANXA2(display_short)|uniprotkb:ANX2(gene name synonym)|uniprotkb:ANX2L4(gene name synonym)|uniprotkb:CAL1H(gene name synonym)|uniprotkb:LPC2D(gene name synonym)|uniprotkb:Annexin-2(gene name synonym)|uniprotkb:Annexin II(gene name synonym)|uniprotkb:Lipocortin II(gene name synonym)|uniprotkb:Calpactin I heavy chain(gene name synonym)|uniprotkb:Chromobindin-8(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:Protein I(gene name synonym)|uniprotkb:Placental anticoagulant protein IV(gene name synonym)|uniprotkb:Calpactin-1 heavy chain(gene name synonym)	psi-mi:s10aa_human(display_long)|uniprotkb:S100 calcium-binding protein A10(gene name synonym)|uniprotkb:Calpactin-1 light chain(gene name synonym)|uniprotkb:Calpactin I light chain(gene name synonym)|uniprotkb:p10 protein(gene name synonym)|uniprotkb:p11(gene name synonym)|uniprotkb:Cellular ligand of annexin II(gene name synonym)|uniprotkb:S100A10(gene name)|psi-mi:S100A10(display_short)|uniprotkb:ANX2LG(gene name synonym)|uniprotkb:CAL1L(gene name synonym)|uniprotkb:CLP11(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Dutta et al. (2014)	imex:IM-25501|pubmed:24457100	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12513025|imex:IM-25501-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001002857.1|refseq:NP_001002858.1|refseq:NP_001129487.1|refseq:NP_004030.1|refseq:XP_016877579.1|refseq:XP_016877580.1|ensembl:ENSG00000182718(gene)|ensembl:ENST00000396024(transcript)|ensembl:ENST00000421017(transcript)|ensembl:ENST00000451270(transcript)|ensembl:ENST00000557906(transcript)|ensembl:ENST00000558558(transcript)|ensembl:ENST00000559818(transcript)|ensembl:ENST00000559956(transcript)|ensembl:ENST00000560468(transcript)|ensembl:ENST00000677968(transcript)|ensembl:ENST00000678061(transcript)|ensembl:ENST00000678450(transcript)|ensembl:ENST00000678870(transcript)|ensembl:ENST00000679109(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001726"(ruffle)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005938"(cell cortex)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0007589"(body fluid secretion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019834"(phospholipase A2 inhibitor activity)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031340"(positive regulation of vesicle fusion)|go:"GO:0031902"(late endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032804"(negative regulation of low-density lipoprotein particle receptor catabolic process)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035749"(myelin sheath adaxonal region)|go:"GO:0036035"(osteoclast development)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0042730"(fibrinolysis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0044090"(positive regulation of vacuole organization)|go:"GO:0044354"(macropinosome)|go:"GO:0044548"(S100 protein binding)|go:"GO:0044730"(bone sialoprotein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046790"(virion binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0005509"(calcium ion binding)|rcsb pdb:2HYU|rcsb pdb:2HYV|rcsb pdb:2HYW|rcsb pdb:4DRW|rcsb pdb:4FTG|rcsb pdb:4HRH|rcsb pdb:5LPU|rcsb pdb:5LPX|rcsb pdb:5LQ0|rcsb pdb:5LQ2|rcsb pdb:5N7D|rcsb pdb:5N7F|rcsb pdb:5N7G|rcsb pdb:6TWQ|rcsb pdb:6TWU|rcsb pdb:6TWX|rcsb pdb:6TWY|reactome:R-HSA-445355|reactome:R-HSA-6798695|reactome:R-HSA-75205|reactome:R-HSA-8950505|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:1905581"(positive regulation of low-density lipoprotein particle clearance)|go:"GO:1905597"(positive regulation of low-density lipoprotein particle receptor binding)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|go:"GO:1905602"(positive regulation of receptor-mediated endocytosis involved in cholesterol transport)|go:"GO:1990665"(AnxA2-p11 complex)|go:"GO:1990667"(PCSK9-AnxA2 complex)|interpro:IPR001464(Annexin)|interpro:IPR002389(Annexin, type II)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P07355|rcsb pdb:1W7B|rcsb pdb:1XJL|go:"GO:0097066"(response to thyroid hormone)	refseq:NP_002957.1|ensembl:ENSG00000197747(gene)|ensembl:ENST00000368809(transcript)|ensembl:ENST00000368811(transcript)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0005576"(extracellular region)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0042493"|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1990665"(AnxA2-p11 complex)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR028476|rcsb pdb:1A4P|rcsb pdb:1BT6|rcsb pdb:4DRW|rcsb pdb:4FTG|rcsb pdb:4HRE|rcsb pdb:4HRG|rcsb pdb:4HRH|reactome:R-HSA-75205	-	-	-	figure legend:6Aiii|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-t47d-a18)|taxid:9606(ER- and PR-positive hormone-responsive clone of t47d)	-	2016/07/19	2016/08/24	rogid:jcB4Dt0LFv8YaBUnC2BSTCshveg9606	rogid:WlxwW4qaHp6tcyEAYvQ2ut9SyRA9606	rigid:oOtMjSYR+6rpqn+rDLfskQBRRZs	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P07355	uniprotkb:P03950	intact:EBI-352622|uniprotkb:Q567R4|uniprotkb:Q96DD5|intact:EBI-2211824|uniprotkb:Q6N0B3|uniprotkb:Q8TBV2|uniprotkb:Q9UDH8|ensembl:ENSP00000379342|ensembl:ENSP00000387545|ensembl:ENSP00000411352|ensembl:ENSP00000452858|ensembl:ENSP00000452895|ensembl:ENSP00000452981|ensembl:ENSP00000453694|ensembl:ENSP00000453859|ensembl:ENSP00000503447|ensembl:ENSP00000503757|ensembl:ENSP00000503855|ensembl:ENSP00000504035|ensembl:ENSP00000504164	intact:EBI-525291|uniprotkb:Q8WXE7|uniprotkb:Q05CV1|uniprotkb:Q53X86|uniprotkb:Q6P5T2|ensembl:ENSP00000336762|ensembl:ENSP00000381077	psi-mi:anxa2_human(display_long)|uniprotkb:ANXA2(gene name)|psi-mi:ANXA2(display_short)|uniprotkb:ANX2(gene name synonym)|uniprotkb:ANX2L4(gene name synonym)|uniprotkb:CAL1H(gene name synonym)|uniprotkb:LPC2D(gene name synonym)|uniprotkb:Annexin-2(gene name synonym)|uniprotkb:Annexin II(gene name synonym)|uniprotkb:Lipocortin II(gene name synonym)|uniprotkb:Calpactin I heavy chain(gene name synonym)|uniprotkb:Chromobindin-8(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:Protein I(gene name synonym)|uniprotkb:Placental anticoagulant protein IV(gene name synonym)|uniprotkb:Calpactin-1 heavy chain(gene name synonym)	psi-mi:angi_human(display_long)|uniprotkb:Ribonuclease 5(gene name synonym)|uniprotkb:ANG(gene name)|psi-mi:ANG(display_short)|uniprotkb:RNASE5(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Dutta et al. (2014)	imex:IM-25501|pubmed:24457100	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12513025|imex:IM-25501-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001002857.1|refseq:NP_001002858.1|refseq:NP_001129487.1|refseq:NP_004030.1|refseq:XP_016877579.1|refseq:XP_016877580.1|ensembl:ENSG00000182718(gene)|ensembl:ENST00000396024(transcript)|ensembl:ENST00000421017(transcript)|ensembl:ENST00000451270(transcript)|ensembl:ENST00000557906(transcript)|ensembl:ENST00000558558(transcript)|ensembl:ENST00000559818(transcript)|ensembl:ENST00000559956(transcript)|ensembl:ENST00000560468(transcript)|ensembl:ENST00000677968(transcript)|ensembl:ENST00000678061(transcript)|ensembl:ENST00000678450(transcript)|ensembl:ENST00000678870(transcript)|ensembl:ENST00000679109(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001726"(ruffle)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005938"(cell cortex)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0007589"(body fluid secretion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019834"(phospholipase A2 inhibitor activity)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031340"(positive regulation of vesicle fusion)|go:"GO:0031902"(late endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032804"(negative regulation of low-density lipoprotein particle receptor catabolic process)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035749"(myelin sheath adaxonal region)|go:"GO:0036035"(osteoclast development)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0042730"(fibrinolysis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0044090"(positive regulation of vacuole organization)|go:"GO:0044354"(macropinosome)|go:"GO:0044548"(S100 protein binding)|go:"GO:0044730"(bone sialoprotein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046790"(virion binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0005509"(calcium ion binding)|rcsb pdb:2HYU|rcsb pdb:2HYV|rcsb pdb:2HYW|rcsb pdb:4DRW|rcsb pdb:4FTG|rcsb pdb:4HRH|rcsb pdb:5LPU|rcsb pdb:5LPX|rcsb pdb:5LQ0|rcsb pdb:5LQ2|rcsb pdb:5N7D|rcsb pdb:5N7F|rcsb pdb:5N7G|rcsb pdb:6TWQ|rcsb pdb:6TWU|rcsb pdb:6TWX|rcsb pdb:6TWY|reactome:R-HSA-445355|reactome:R-HSA-6798695|reactome:R-HSA-75205|reactome:R-HSA-8950505|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:1905581"(positive regulation of low-density lipoprotein particle clearance)|go:"GO:1905597"(positive regulation of low-density lipoprotein particle receptor binding)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|go:"GO:1905602"(positive regulation of receptor-mediated endocytosis involved in cholesterol transport)|go:"GO:1990665"(AnxA2-p11 complex)|go:"GO:1990667"(PCSK9-AnxA2 complex)|interpro:IPR001464(Annexin)|interpro:IPR002389(Annexin, type II)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P07355|rcsb pdb:1W7B|rcsb pdb:1XJL|go:"GO:0097066"(response to thyroid hormone)	refseq:NP_001091046.1|refseq:NP_001136.1|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0019732"(antifungal humoral response)|go:"GO:0019843"(rRNA binding)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030426"(growth cone)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0032311"(angiogenin-PRI complex)|go:"GO:0032431"(activation of phospholipase A2 activity)|go:"GO:0042277"(peptide binding)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042592"(homeostatic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045087"(innate immune response)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR001427(Pancreatic ribonuclease)|interpro:IPR023411|interpro:IPR023412|interpro:IPR036816|rcsb pdb:1A4Y|rcsb pdb:1ANG|go:"GO:0016078"(tRNA catabolic process)|go:"GO:0016477"(cell migration)|rcsb pdb:1AWZ|rcsb pdb:1B1E|rcsb pdb:1B1I|rcsb pdb:1B1J|rcsb pdb:1GV7|rcsb pdb:1H0D|rcsb pdb:1H52|rcsb pdb:1H53|rcsb pdb:1HBY|rcsb pdb:1K58|rcsb pdb:1K59|rcsb pdb:1K5A|rcsb pdb:1K5B|rcsb pdb:1UN3|rcsb pdb:1UN4|rcsb pdb:1UN5|rcsb pdb:2ANG|rcsb pdb:4AHD|rcsb pdb:4AHE|rcsb pdb:4AHF|rcsb pdb:4AHG|rcsb pdb:4AHH|rcsb pdb:4AHI|rcsb pdb:4AHJ|rcsb pdb:4AHK|rcsb pdb:4AHL|rcsb pdb:4AHM|rcsb pdb:4AHN|rcsb pdb:4AOH|rcsb pdb:4B36|rcsb pdb:5EOP|rcsb pdb:5EPZ|rcsb pdb:5EQO|rcsb pdb:5M9A|rcsb pdb:5M9C|rcsb pdb:5M9G|rcsb pdb:5M9J|rcsb pdb:5M9M|rcsb pdb:5M9P|rcsb pdb:5M9Q|rcsb pdb:5M9R|rcsb pdb:5M9S|rcsb pdb:5M9T|rcsb pdb:5M9V|reactome:R-HSA-418990|reactome:R-HSA-9708296|ensembl:ENSG00000214274(gene)|ensembl:ENST00000336811(transcript)|ensembl:ENST00000397990(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001878"(response to yeast)|go:"GO:0001890"(placenta development)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0003677"(DNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0004540"(ribonuclease activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005507"(copper ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006651"(diacylglycerol biosynthetic process)|go:"GO:0007154"(cell communication)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0008201"(heparin binding)|go:"GO:0009303"(rRNA transcription)|go:"GO:0009725"(response to hormone)|go:"GO:0015629"(actin cytoskeleton)	-	-	-	figure legend:6Aiii|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-t47d-a18)|taxid:9606(ER- and PR-positive hormone-responsive clone of t47d)	-	2016/07/19	2016/08/24	rogid:jcB4Dt0LFv8YaBUnC2BSTCshveg9606	rogid:CSOTublnrV3DIGJfeyCfT14p8m89606	rigid:oOtMjSYR+6rpqn+rDLfskQBRRZs	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q03405	uniprotkb:P03950	intact:EBI-716505|uniprotkb:Q12876|uniprotkb:Q15845|uniprotkb:Q16887|uniprotkb:Q6IB52|uniprotkb:Q9BWT0|uniprotkb:Q9NYC8|uniprotkb:Q9UD69|uniprotkb:Q9UEA6|uniprotkb:Q9UM92|uniprotkb:Q9UMV0|uniprotkb:A8K409|ensembl:ENSP00000339328	intact:EBI-525291|uniprotkb:Q8WXE7|uniprotkb:Q05CV1|uniprotkb:Q53X86|uniprotkb:Q6P5T2|ensembl:ENSP00000336762|ensembl:ENSP00000381077	psi-mi:upar_human(display_long)|uniprotkb:Monocyte activation antigen Mo3(gene name synonym)|uniprotkb:PLAUR(gene name)|psi-mi:PLAUR(display_short)|uniprotkb:MO3(gene name synonym)|uniprotkb:UPAR(gene name synonym)	psi-mi:angi_human(display_long)|uniprotkb:Ribonuclease 5(gene name synonym)|uniprotkb:ANG(gene name)|psi-mi:ANG(display_short)|uniprotkb:RNASE5(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Dutta et al. (2014)	imex:IM-25501|pubmed:24457100	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12513037|imex:IM-25501-23	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001005376.1|refseq:NP_001005377.1|refseq:NP_002650.1|reactome:R-HSA-162791|reactome:R-HSA-6798695|reactome:R-HSA-75205|rcsb pdb:4QTI|ensembl:ENSG00000011422(gene)|ensembl:ENST00000340093(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006935"(chemotaxis)|go:"GO:0007165"(signal transduction)|go:"GO:0007596"(blood coagulation)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030162"(regulation of proteolysis)|go:"GO:0030377"(urokinase plasminogen activator receptor activity)|go:"GO:0034112"(positive regulation of homotypic cell-cell adhesion)|go:"GO:0035579"(specific granule membrane)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042995"(cell projection)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|go:"GO:0031225"(anchored component of membrane)|go:"GO:2001268"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|interpro:IPR018363|interpro:IPR033084|rcsb pdb:1YWH|rcsb pdb:2FD6|rcsb pdb:2I9B|rcsb pdb:3BT1|rcsb pdb:3BT2|rcsb pdb:3U73|rcsb pdb:3U74|rcsb pdb:4K24|refseq:NP_001287966.1|dip:DIP-137N	refseq:NP_001091046.1|refseq:NP_001136.1|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0019732"(antifungal humoral response)|go:"GO:0019843"(rRNA binding)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030426"(growth cone)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0032311"(angiogenin-PRI complex)|go:"GO:0032431"(activation of phospholipase A2 activity)|go:"GO:0042277"(peptide binding)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042592"(homeostatic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045087"(innate immune response)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR001427(Pancreatic ribonuclease)|interpro:IPR023411|interpro:IPR023412|interpro:IPR036816|rcsb pdb:1A4Y|rcsb pdb:1ANG|go:"GO:0016078"(tRNA catabolic process)|go:"GO:0016477"(cell migration)|rcsb pdb:1AWZ|rcsb pdb:1B1E|rcsb pdb:1B1I|rcsb pdb:1B1J|rcsb pdb:1GV7|rcsb pdb:1H0D|rcsb pdb:1H52|rcsb pdb:1H53|rcsb pdb:1HBY|rcsb pdb:1K58|rcsb pdb:1K59|rcsb pdb:1K5A|rcsb pdb:1K5B|rcsb pdb:1UN3|rcsb pdb:1UN4|rcsb pdb:1UN5|rcsb pdb:2ANG|rcsb pdb:4AHD|rcsb pdb:4AHE|rcsb pdb:4AHF|rcsb pdb:4AHG|rcsb pdb:4AHH|rcsb pdb:4AHI|rcsb pdb:4AHJ|rcsb pdb:4AHK|rcsb pdb:4AHL|rcsb pdb:4AHM|rcsb pdb:4AHN|rcsb pdb:4AOH|rcsb pdb:4B36|rcsb pdb:5EOP|rcsb pdb:5EPZ|rcsb pdb:5EQO|rcsb pdb:5M9A|rcsb pdb:5M9C|rcsb pdb:5M9G|rcsb pdb:5M9J|rcsb pdb:5M9M|rcsb pdb:5M9P|rcsb pdb:5M9Q|rcsb pdb:5M9R|rcsb pdb:5M9S|rcsb pdb:5M9T|rcsb pdb:5M9V|reactome:R-HSA-418990|reactome:R-HSA-9708296|ensembl:ENSG00000214274(gene)|ensembl:ENST00000336811(transcript)|ensembl:ENST00000397990(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001878"(response to yeast)|go:"GO:0001890"(placenta development)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0003677"(DNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0004540"(ribonuclease activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005507"(copper ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006651"(diacylglycerol biosynthetic process)|go:"GO:0007154"(cell communication)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0008201"(heparin binding)|go:"GO:0009303"(rRNA transcription)|go:"GO:0009725"(response to hormone)|go:"GO:0015629"(actin cytoskeleton)	-	-	-	figure legend:6Aiv|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-t47d-a18)|taxid:9606(ER- and PR-positive hormone-responsive clone of t47d)	-	2016/07/19	2016/08/24	rogid:faxxSUpKpPAaAlPpUpvg2NG4DOA9606	rogid:CSOTublnrV3DIGJfeyCfT14p8m89606	rigid:MoQU+5+dO8o7aWpoudCs4v1TnPQ	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P00749	uniprotkb:P03950	intact:EBI-3905042|uniprotkb:Q15844|uniprotkb:B4DPZ2|uniprotkb:Q53XS3|uniprotkb:Q16618|uniprotkb:Q5SWW9|uniprotkb:Q969W6|ensembl:ENSP00000361850	intact:EBI-525291|uniprotkb:Q8WXE7|uniprotkb:Q05CV1|uniprotkb:Q53X86|uniprotkb:Q6P5T2|ensembl:ENSP00000336762|ensembl:ENSP00000381077	psi-mi:urok_human(display_long)|uniprotkb:PLAU(gene name)|psi-mi:PLAU(display_short)	psi-mi:angi_human(display_long)|uniprotkb:Ribonuclease 5(gene name synonym)|uniprotkb:ANG(gene name)|psi-mi:ANG(display_short)|uniprotkb:RNASE5(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Dutta et al. (2014)	imex:IM-25501|pubmed:24457100	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12513121|imex:IM-25501-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001138503.1|refseq:NP_002649.1|dip:DIP-46387N|refseq:NP_001306120.1|rcsb pdb:4MNX|rcsb pdb:4MNY|rcsb pdb:4OS1|rcsb pdb:4OS2|rcsb pdb:4OS4|rcsb pdb:4OS5|rcsb pdb:4OS6|rcsb pdb:4OS7|rcsb pdb:4X0W|rcsb pdb:4X1N|rcsb pdb:4X1P|rcsb pdb:4X1Q|rcsb pdb:4X1R|rcsb pdb:4X1S|rcsb pdb:4XSK|rcsb pdb:4ZHL|rcsb pdb:4ZHM|rcsb pdb:4ZKN|rcsb pdb:4ZKO|rcsb pdb:4ZKR|rcsb pdb:4ZKS|ensembl:ENSG00000122861(gene)|ensembl:ENST00000372764(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006508"(proteolysis)|go:"GO:0006935"(chemotaxis)|go:"GO:0007165"(signal transduction)|go:"GO:0007596"(blood coagulation)|go:"GO:0009986"(cell surface)|go:"GO:0010469"(regulation of signaling receptor activity)|go:"GO:0014909"(smooth muscle cell migration)|go:"GO:0014910"(regulation of smooth muscle cell migration)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031639"(plasminogen activation)|go:"GO:0033628"(regulation of cell adhesion mediated by integrin)|go:"GO:0035579"(specific granule membrane)|go:"GO:0042730"(fibrinolysis)|go:"GO:0061041"(regulation of wound healing)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:2000097"(regulation of smooth muscle cell-matrix adhesion)|interpro:IPR000001(Kringle)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR018114|interpro:IPR033116|interpro:IPR034814|interpro:IPR038178|interpro:IPR043504|rcsb pdb:1C5W|rcsb pdb:1C5X|rcsb pdb:1C5Y|rcsb pdb:1C5Z|rcsb pdb:1EJN|rcsb pdb:1F5K|go:"GO:0042127"(regulation of cell population proliferation)|rcsb pdb:1F5L|rcsb pdb:1F92|rcsb pdb:5ZAH|rcsb pdb:5ZAJ|rcsb pdb:5ZC5|rcsb pdb:6AG2|rcsb pdb:6AG3|rcsb pdb:6AG7|rcsb pdb:6AG9|rcsb pdb:6JYP|rcsb pdb:6JYQ|rcsb pdb:6L04|rcsb pdb:6L05|rcsb pdb:6NMB|rcsb pdb:6XVD|reactome:R-HSA-6798695|reactome:R-HSA-75205|rcsb pdb:5HGG|rcsb pdb:5WXF|rcsb pdb:5WXO|rcsb pdb:5WXP|rcsb pdb:5WXQ|rcsb pdb:5WXR|rcsb pdb:5WXS|rcsb pdb:5WXT|rcsb pdb:5XG4|rcsb pdb:5YC6|rcsb pdb:5YC7|rcsb pdb:5Z1C|rcsb pdb:5ZA7|rcsb pdb:5ZA8|rcsb pdb:5ZA9|rcsb pdb:5ZAE|rcsb pdb:5ZAF|rcsb pdb:5ZAG|rcsb pdb:1O5A|rcsb pdb:1O5B|rcsb pdb:1O5C|rcsb pdb:1OWD|rcsb pdb:1OWE|rcsb pdb:1OWH|rcsb pdb:1OWI|rcsb pdb:1OWJ|rcsb pdb:1OWK|rcsb pdb:1SC8|rcsb pdb:1SQA|rcsb pdb:1SQO|rcsb pdb:1SQT|rcsb pdb:1U6Q|rcsb pdb:1URK|rcsb pdb:1VJ9|rcsb pdb:1VJA|rcsb pdb:1W0Z|rcsb pdb:1W10|rcsb pdb:1W11|rcsb pdb:1W12|rcsb pdb:1W13|rcsb pdb:1W14|rcsb pdb:1FV9|rcsb pdb:1GI7|rcsb pdb:1GI8|rcsb pdb:1GI9|rcsb pdb:1GJ7|rcsb pdb:1GJ8|rcsb pdb:1GJ9|rcsb pdb:1GJA|rcsb pdb:1GJB|rcsb pdb:1GJC|rcsb pdb:1GJD|rcsb pdb:1KDU|rcsb pdb:1LMW|rcsb pdb:1O3P|rcsb pdb:2FD6|rcsb pdb:2I9A|rcsb pdb:2I9B|rcsb pdb:2NWN|rcsb pdb:2O8T|rcsb pdb:2O8U|rcsb pdb:2O8W|rcsb pdb:2R2W|rcsb pdb:2VIN|rcsb pdb:2VIO|rcsb pdb:2VIP|rcsb pdb:2VIQ|rcsb pdb:2VIV|rcsb pdb:2VIW|rcsb pdb:2VNT|rcsb pdb:3BT1|rcsb pdb:3BT2|rcsb pdb:3IG6|rcsb pdb:3KGP|rcsb pdb:3KHV|rcsb pdb:3KID|rcsb pdb:3M61|rcsb pdb:3MHW|rcsb pdb:3MWI|rcsb pdb:3OX7|rcsb pdb:3OY5|rcsb pdb:3OY6|rcsb pdb:3PB1|rcsb pdb:3QN7|rcsb pdb:3U73|rcsb pdb:4DVA|rcsb pdb:4DW2|rcsb pdb:4FU7|rcsb pdb:4FU8|rcsb pdb:4FU9|rcsb pdb:4FUB|rcsb pdb:4FUC|rcsb pdb:4FUD|rcsb pdb:4FUE|rcsb pdb:4FUF|rcsb pdb:4FUG|rcsb pdb:4FUH|rcsb pdb:4FUI|rcsb pdb:4FUJ|rcsb pdb:4GLY|rcsb pdb:4H42|rcsb pdb:4JK5|rcsb pdb:4JK6|rcsb pdb:4K24|rcsb pdb:4MNV|rcsb pdb:4MNW	refseq:NP_001091046.1|refseq:NP_001136.1|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0019732"(antifungal humoral response)|go:"GO:0019843"(rRNA binding)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030426"(growth cone)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0032311"(angiogenin-PRI complex)|go:"GO:0032431"(activation of phospholipase A2 activity)|go:"GO:0042277"(peptide binding)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042592"(homeostatic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045087"(innate immune response)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR001427(Pancreatic ribonuclease)|interpro:IPR023411|interpro:IPR023412|interpro:IPR036816|rcsb pdb:1A4Y|rcsb pdb:1ANG|go:"GO:0016078"(tRNA catabolic process)|go:"GO:0016477"(cell migration)|rcsb pdb:1AWZ|rcsb pdb:1B1E|rcsb pdb:1B1I|rcsb pdb:1B1J|rcsb pdb:1GV7|rcsb pdb:1H0D|rcsb pdb:1H52|rcsb pdb:1H53|rcsb pdb:1HBY|rcsb pdb:1K58|rcsb pdb:1K59|rcsb pdb:1K5A|rcsb pdb:1K5B|rcsb pdb:1UN3|rcsb pdb:1UN4|rcsb pdb:1UN5|rcsb pdb:2ANG|rcsb pdb:4AHD|rcsb pdb:4AHE|rcsb pdb:4AHF|rcsb pdb:4AHG|rcsb pdb:4AHH|rcsb pdb:4AHI|rcsb pdb:4AHJ|rcsb pdb:4AHK|rcsb pdb:4AHL|rcsb pdb:4AHM|rcsb pdb:4AHN|rcsb pdb:4AOH|rcsb pdb:4B36|rcsb pdb:5EOP|rcsb pdb:5EPZ|rcsb pdb:5EQO|rcsb pdb:5M9A|rcsb pdb:5M9C|rcsb pdb:5M9G|rcsb pdb:5M9J|rcsb pdb:5M9M|rcsb pdb:5M9P|rcsb pdb:5M9Q|rcsb pdb:5M9R|rcsb pdb:5M9S|rcsb pdb:5M9T|rcsb pdb:5M9V|reactome:R-HSA-418990|reactome:R-HSA-9708296|ensembl:ENSG00000214274(gene)|ensembl:ENST00000336811(transcript)|ensembl:ENST00000397990(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001878"(response to yeast)|go:"GO:0001890"(placenta development)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0003677"(DNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0004540"(ribonuclease activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005507"(copper ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006651"(diacylglycerol biosynthetic process)|go:"GO:0007154"(cell communication)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0008201"(heparin binding)|go:"GO:0009303"(rRNA transcription)|go:"GO:0009725"(response to hormone)|go:"GO:0015629"(actin cytoskeleton)	-	-	-	figure legend:11B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-t47d-a18)|taxid:9606(ER- and PR-positive hormone-responsive clone of t47d)	-	2016/07/19	2016/08/24	rogid:UgdiI+n26oe/Pa7q8Le493SlNE89606	rogid:CSOTublnrV3DIGJfeyCfT14p8m89606	rigid:Ko238EFc/mxw0OFQ6gM9BXpdGc0	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P00749	uniprotkb:Q03405	intact:EBI-3905042|uniprotkb:Q15844|uniprotkb:B4DPZ2|uniprotkb:Q53XS3|uniprotkb:Q16618|uniprotkb:Q5SWW9|uniprotkb:Q969W6|ensembl:ENSP00000361850	intact:EBI-716505|uniprotkb:Q12876|uniprotkb:Q15845|uniprotkb:Q16887|uniprotkb:Q6IB52|uniprotkb:Q9BWT0|uniprotkb:Q9NYC8|uniprotkb:Q9UD69|uniprotkb:Q9UEA6|uniprotkb:Q9UM92|uniprotkb:Q9UMV0|uniprotkb:A8K409|ensembl:ENSP00000339328	psi-mi:urok_human(display_long)|uniprotkb:PLAU(gene name)|psi-mi:PLAU(display_short)	psi-mi:upar_human(display_long)|uniprotkb:Monocyte activation antigen Mo3(gene name synonym)|uniprotkb:PLAUR(gene name)|psi-mi:PLAUR(display_short)|uniprotkb:MO3(gene name synonym)|uniprotkb:UPAR(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Dutta et al. (2014)	imex:IM-25501|pubmed:24457100	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12513121|imex:IM-25501-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001138503.1|refseq:NP_002649.1|dip:DIP-46387N|refseq:NP_001306120.1|rcsb pdb:4MNX|rcsb pdb:4MNY|rcsb pdb:4OS1|rcsb pdb:4OS2|rcsb pdb:4OS4|rcsb pdb:4OS5|rcsb pdb:4OS6|rcsb pdb:4OS7|rcsb pdb:4X0W|rcsb pdb:4X1N|rcsb pdb:4X1P|rcsb pdb:4X1Q|rcsb pdb:4X1R|rcsb pdb:4X1S|rcsb pdb:4XSK|rcsb pdb:4ZHL|rcsb pdb:4ZHM|rcsb pdb:4ZKN|rcsb pdb:4ZKO|rcsb pdb:4ZKR|rcsb pdb:4ZKS|ensembl:ENSG00000122861(gene)|ensembl:ENST00000372764(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006508"(proteolysis)|go:"GO:0006935"(chemotaxis)|go:"GO:0007165"(signal transduction)|go:"GO:0007596"(blood coagulation)|go:"GO:0009986"(cell surface)|go:"GO:0010469"(regulation of signaling receptor activity)|go:"GO:0014909"(smooth muscle cell migration)|go:"GO:0014910"(regulation of smooth muscle cell migration)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031639"(plasminogen activation)|go:"GO:0033628"(regulation of cell adhesion mediated by integrin)|go:"GO:0035579"(specific granule membrane)|go:"GO:0042730"(fibrinolysis)|go:"GO:0061041"(regulation of wound healing)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:2000097"(regulation of smooth muscle cell-matrix adhesion)|interpro:IPR000001(Kringle)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR018114|interpro:IPR033116|interpro:IPR034814|interpro:IPR038178|interpro:IPR043504|rcsb pdb:1C5W|rcsb pdb:1C5X|rcsb pdb:1C5Y|rcsb pdb:1C5Z|rcsb pdb:1EJN|rcsb pdb:1F5K|go:"GO:0042127"(regulation of cell population proliferation)|rcsb pdb:1F5L|rcsb pdb:1F92|rcsb pdb:5ZAH|rcsb pdb:5ZAJ|rcsb pdb:5ZC5|rcsb pdb:6AG2|rcsb pdb:6AG3|rcsb pdb:6AG7|rcsb pdb:6AG9|rcsb pdb:6JYP|rcsb pdb:6JYQ|rcsb pdb:6L04|rcsb pdb:6L05|rcsb pdb:6NMB|rcsb pdb:6XVD|reactome:R-HSA-6798695|reactome:R-HSA-75205|rcsb pdb:5HGG|rcsb pdb:5WXF|rcsb pdb:5WXO|rcsb pdb:5WXP|rcsb pdb:5WXQ|rcsb pdb:5WXR|rcsb pdb:5WXS|rcsb pdb:5WXT|rcsb pdb:5XG4|rcsb pdb:5YC6|rcsb pdb:5YC7|rcsb pdb:5Z1C|rcsb pdb:5ZA7|rcsb pdb:5ZA8|rcsb pdb:5ZA9|rcsb pdb:5ZAE|rcsb pdb:5ZAF|rcsb pdb:5ZAG|rcsb pdb:1O5A|rcsb pdb:1O5B|rcsb pdb:1O5C|rcsb pdb:1OWD|rcsb pdb:1OWE|rcsb pdb:1OWH|rcsb pdb:1OWI|rcsb pdb:1OWJ|rcsb pdb:1OWK|rcsb pdb:1SC8|rcsb pdb:1SQA|rcsb pdb:1SQO|rcsb pdb:1SQT|rcsb pdb:1U6Q|rcsb pdb:1URK|rcsb pdb:1VJ9|rcsb pdb:1VJA|rcsb pdb:1W0Z|rcsb pdb:1W10|rcsb pdb:1W11|rcsb pdb:1W12|rcsb pdb:1W13|rcsb pdb:1W14|rcsb pdb:1FV9|rcsb pdb:1GI7|rcsb pdb:1GI8|rcsb pdb:1GI9|rcsb pdb:1GJ7|rcsb pdb:1GJ8|rcsb pdb:1GJ9|rcsb pdb:1GJA|rcsb pdb:1GJB|rcsb pdb:1GJC|rcsb pdb:1GJD|rcsb pdb:1KDU|rcsb pdb:1LMW|rcsb pdb:1O3P|rcsb pdb:2FD6|rcsb pdb:2I9A|rcsb pdb:2I9B|rcsb pdb:2NWN|rcsb pdb:2O8T|rcsb pdb:2O8U|rcsb pdb:2O8W|rcsb pdb:2R2W|rcsb pdb:2VIN|rcsb pdb:2VIO|rcsb pdb:2VIP|rcsb pdb:2VIQ|rcsb pdb:2VIV|rcsb pdb:2VIW|rcsb pdb:2VNT|rcsb pdb:3BT1|rcsb pdb:3BT2|rcsb pdb:3IG6|rcsb pdb:3KGP|rcsb pdb:3KHV|rcsb pdb:3KID|rcsb pdb:3M61|rcsb pdb:3MHW|rcsb pdb:3MWI|rcsb pdb:3OX7|rcsb pdb:3OY5|rcsb pdb:3OY6|rcsb pdb:3PB1|rcsb pdb:3QN7|rcsb pdb:3U73|rcsb pdb:4DVA|rcsb pdb:4DW2|rcsb pdb:4FU7|rcsb pdb:4FU8|rcsb pdb:4FU9|rcsb pdb:4FUB|rcsb pdb:4FUC|rcsb pdb:4FUD|rcsb pdb:4FUE|rcsb pdb:4FUF|rcsb pdb:4FUG|rcsb pdb:4FUH|rcsb pdb:4FUI|rcsb pdb:4FUJ|rcsb pdb:4GLY|rcsb pdb:4H42|rcsb pdb:4JK5|rcsb pdb:4JK6|rcsb pdb:4K24|rcsb pdb:4MNV|rcsb pdb:4MNW	refseq:NP_001005376.1|refseq:NP_001005377.1|refseq:NP_002650.1|reactome:R-HSA-162791|reactome:R-HSA-6798695|reactome:R-HSA-75205|rcsb pdb:4QTI|ensembl:ENSG00000011422(gene)|ensembl:ENST00000340093(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006935"(chemotaxis)|go:"GO:0007165"(signal transduction)|go:"GO:0007596"(blood coagulation)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030162"(regulation of proteolysis)|go:"GO:0030377"(urokinase plasminogen activator receptor activity)|go:"GO:0034112"(positive regulation of homotypic cell-cell adhesion)|go:"GO:0035579"(specific granule membrane)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042995"(cell projection)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|go:"GO:0031225"(anchored component of membrane)|go:"GO:2001268"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|interpro:IPR018363|interpro:IPR033084|rcsb pdb:1YWH|rcsb pdb:2FD6|rcsb pdb:2I9B|rcsb pdb:3BT1|rcsb pdb:3BT2|rcsb pdb:3U73|rcsb pdb:3U74|rcsb pdb:4K24|refseq:NP_001287966.1|dip:DIP-137N	-	-	-	figure legend:11B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-t47d-a18)|taxid:9606(ER- and PR-positive hormone-responsive clone of t47d)	-	2016/07/19	2016/08/24	rogid:UgdiI+n26oe/Pa7q8Le493SlNE89606	rogid:faxxSUpKpPAaAlPpUpvg2NG4DOA9606	rigid:Ko238EFc/mxw0OFQ6gM9BXpdGc0	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P03950	uniprotkb:P60903	intact:EBI-525291|uniprotkb:Q8WXE7|uniprotkb:Q05CV1|uniprotkb:Q53X86|uniprotkb:Q6P5T2|ensembl:ENSP00000336762|ensembl:ENSP00000381077	intact:EBI-717048|uniprotkb:P08206|uniprotkb:Q5T1C5|uniprotkb:A8K4V8|ensembl:ENSP00000357799|ensembl:ENSP00000357801	psi-mi:angi_human(display_long)|uniprotkb:Ribonuclease 5(gene name synonym)|uniprotkb:ANG(gene name)|psi-mi:ANG(display_short)|uniprotkb:RNASE5(gene name synonym)	psi-mi:s10aa_human(display_long)|uniprotkb:S100 calcium-binding protein A10(gene name synonym)|uniprotkb:Calpactin-1 light chain(gene name synonym)|uniprotkb:Calpactin I light chain(gene name synonym)|uniprotkb:p10 protein(gene name synonym)|uniprotkb:p11(gene name synonym)|uniprotkb:Cellular ligand of annexin II(gene name synonym)|uniprotkb:S100A10(gene name)|psi-mi:S100A10(display_short)|uniprotkb:ANX2LG(gene name synonym)|uniprotkb:CAL1L(gene name synonym)|uniprotkb:CLP11(gene name synonym)	psi-mi:"MI:0813"(proximity ligation assay)	Dutta et al. (2014)	imex:IM-25501|pubmed:24457100	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12513069|imex:IM-25501-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001091046.1|refseq:NP_001136.1|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0019732"(antifungal humoral response)|go:"GO:0019843"(rRNA binding)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030426"(growth cone)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0032311"(angiogenin-PRI complex)|go:"GO:0032431"(activation of phospholipase A2 activity)|go:"GO:0042277"(peptide binding)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042592"(homeostatic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045087"(innate immune response)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR001427(Pancreatic ribonuclease)|interpro:IPR023411|interpro:IPR023412|interpro:IPR036816|rcsb pdb:1A4Y|rcsb pdb:1ANG|go:"GO:0016078"(tRNA catabolic process)|go:"GO:0016477"(cell migration)|rcsb pdb:1AWZ|rcsb pdb:1B1E|rcsb pdb:1B1I|rcsb pdb:1B1J|rcsb pdb:1GV7|rcsb pdb:1H0D|rcsb pdb:1H52|rcsb pdb:1H53|rcsb pdb:1HBY|rcsb pdb:1K58|rcsb pdb:1K59|rcsb pdb:1K5A|rcsb pdb:1K5B|rcsb pdb:1UN3|rcsb pdb:1UN4|rcsb pdb:1UN5|rcsb pdb:2ANG|rcsb pdb:4AHD|rcsb pdb:4AHE|rcsb pdb:4AHF|rcsb pdb:4AHG|rcsb pdb:4AHH|rcsb pdb:4AHI|rcsb pdb:4AHJ|rcsb pdb:4AHK|rcsb pdb:4AHL|rcsb pdb:4AHM|rcsb pdb:4AHN|rcsb pdb:4AOH|rcsb pdb:4B36|rcsb pdb:5EOP|rcsb pdb:5EPZ|rcsb pdb:5EQO|rcsb pdb:5M9A|rcsb pdb:5M9C|rcsb pdb:5M9G|rcsb pdb:5M9J|rcsb pdb:5M9M|rcsb pdb:5M9P|rcsb pdb:5M9Q|rcsb pdb:5M9R|rcsb pdb:5M9S|rcsb pdb:5M9T|rcsb pdb:5M9V|reactome:R-HSA-418990|reactome:R-HSA-9708296|ensembl:ENSG00000214274(gene)|ensembl:ENST00000336811(transcript)|ensembl:ENST00000397990(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001878"(response to yeast)|go:"GO:0001890"(placenta development)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0003677"(DNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0004540"(ribonuclease activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005507"(copper ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006651"(diacylglycerol biosynthetic process)|go:"GO:0007154"(cell communication)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0008201"(heparin binding)|go:"GO:0009303"(rRNA transcription)|go:"GO:0009725"(response to hormone)|go:"GO:0015629"(actin cytoskeleton)	refseq:NP_002957.1|ensembl:ENSG00000197747(gene)|ensembl:ENST00000368809(transcript)|ensembl:ENST00000368811(transcript)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0005576"(extracellular region)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0042493"|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1990665"(AnxA2-p11 complex)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR028476|rcsb pdb:1A4P|rcsb pdb:1BT6|rcsb pdb:4DRW|rcsb pdb:4FTG|rcsb pdb:4HRE|rcsb pdb:4HRG|rcsb pdb:4HRH|reactome:R-HSA-75205	-	-	-	figure legend:6C-2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-t47d-a18)|taxid:9606(ER- and PR-positive hormone-responsive clone of t47d)	-	2016/07/19	2016/08/24	rogid:CSOTublnrV3DIGJfeyCfT14p8m89606	rogid:WlxwW4qaHp6tcyEAYvQ2ut9SyRA9606	rigid:9Xf/xc8o3UvT8j61sO1tnaJwn84	false	-	-	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:P03950	uniprotkb:P60903	intact:EBI-525291|uniprotkb:Q8WXE7|uniprotkb:Q05CV1|uniprotkb:Q53X86|uniprotkb:Q6P5T2|ensembl:ENSP00000336762|ensembl:ENSP00000381077	intact:EBI-717048|uniprotkb:P08206|uniprotkb:Q5T1C5|uniprotkb:A8K4V8|ensembl:ENSP00000357799|ensembl:ENSP00000357801	psi-mi:angi_human(display_long)|uniprotkb:Ribonuclease 5(gene name synonym)|uniprotkb:ANG(gene name)|psi-mi:ANG(display_short)|uniprotkb:RNASE5(gene name synonym)	psi-mi:s10aa_human(display_long)|uniprotkb:S100 calcium-binding protein A10(gene name synonym)|uniprotkb:Calpactin-1 light chain(gene name synonym)|uniprotkb:Calpactin I light chain(gene name synonym)|uniprotkb:p10 protein(gene name synonym)|uniprotkb:p11(gene name synonym)|uniprotkb:Cellular ligand of annexin II(gene name synonym)|uniprotkb:S100A10(gene name)|psi-mi:S100A10(display_short)|uniprotkb:ANX2LG(gene name synonym)|uniprotkb:CAL1L(gene name synonym)|uniprotkb:CLP11(gene name synonym)	psi-mi:"MI:0813"(proximity ligation assay)	Dutta et al. (2014)	imex:IM-25501|pubmed:24457100	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12513063|imex:IM-25501-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001091046.1|refseq:NP_001136.1|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0019732"(antifungal humoral response)|go:"GO:0019843"(rRNA binding)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030426"(growth cone)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0032311"(angiogenin-PRI complex)|go:"GO:0032431"(activation of phospholipase A2 activity)|go:"GO:0042277"(peptide binding)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042592"(homeostatic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045087"(innate immune response)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR001427(Pancreatic ribonuclease)|interpro:IPR023411|interpro:IPR023412|interpro:IPR036816|rcsb pdb:1A4Y|rcsb pdb:1ANG|go:"GO:0016078"(tRNA catabolic process)|go:"GO:0016477"(cell migration)|rcsb pdb:1AWZ|rcsb pdb:1B1E|rcsb pdb:1B1I|rcsb pdb:1B1J|rcsb pdb:1GV7|rcsb pdb:1H0D|rcsb pdb:1H52|rcsb pdb:1H53|rcsb pdb:1HBY|rcsb pdb:1K58|rcsb pdb:1K59|rcsb pdb:1K5A|rcsb pdb:1K5B|rcsb pdb:1UN3|rcsb pdb:1UN4|rcsb pdb:1UN5|rcsb pdb:2ANG|rcsb pdb:4AHD|rcsb pdb:4AHE|rcsb pdb:4AHF|rcsb pdb:4AHG|rcsb pdb:4AHH|rcsb pdb:4AHI|rcsb pdb:4AHJ|rcsb pdb:4AHK|rcsb pdb:4AHL|rcsb pdb:4AHM|rcsb pdb:4AHN|rcsb pdb:4AOH|rcsb pdb:4B36|rcsb pdb:5EOP|rcsb pdb:5EPZ|rcsb pdb:5EQO|rcsb pdb:5M9A|rcsb pdb:5M9C|rcsb pdb:5M9G|rcsb pdb:5M9J|rcsb pdb:5M9M|rcsb pdb:5M9P|rcsb pdb:5M9Q|rcsb pdb:5M9R|rcsb pdb:5M9S|rcsb pdb:5M9T|rcsb pdb:5M9V|reactome:R-HSA-418990|reactome:R-HSA-9708296|ensembl:ENSG00000214274(gene)|ensembl:ENST00000336811(transcript)|ensembl:ENST00000397990(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001878"(response to yeast)|go:"GO:0001890"(placenta development)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0003677"(DNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0004540"(ribonuclease activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005507"(copper ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006651"(diacylglycerol biosynthetic process)|go:"GO:0007154"(cell communication)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0008201"(heparin binding)|go:"GO:0009303"(rRNA transcription)|go:"GO:0009725"(response to hormone)|go:"GO:0015629"(actin cytoskeleton)	refseq:NP_002957.1|ensembl:ENSG00000197747(gene)|ensembl:ENST00000368809(transcript)|ensembl:ENST00000368811(transcript)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0005576"(extracellular region)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0042493"|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1990665"(AnxA2-p11 complex)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR028476|rcsb pdb:1A4P|rcsb pdb:1BT6|rcsb pdb:4DRW|rcsb pdb:4FTG|rcsb pdb:4HRE|rcsb pdb:4HRG|rcsb pdb:4HRH|reactome:R-HSA-75205	-	-	-	figure legend:6C-4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-t47d-a18)|taxid:9606(ER- and PR-positive hormone-responsive clone of t47d)	-	2016/07/19	2016/08/24	rogid:CSOTublnrV3DIGJfeyCfT14p8m89606	rogid:WlxwW4qaHp6tcyEAYvQ2ut9SyRA9606	rigid:9Xf/xc8o3UvT8j61sO1tnaJwn84	false	-	-	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:P07355	uniprotkb:P03950	intact:EBI-352622|uniprotkb:Q567R4|uniprotkb:Q96DD5|intact:EBI-2211824|uniprotkb:Q6N0B3|uniprotkb:Q8TBV2|uniprotkb:Q9UDH8|ensembl:ENSP00000379342|ensembl:ENSP00000387545|ensembl:ENSP00000411352|ensembl:ENSP00000452858|ensembl:ENSP00000452895|ensembl:ENSP00000452981|ensembl:ENSP00000453694|ensembl:ENSP00000453859|ensembl:ENSP00000503447|ensembl:ENSP00000503757|ensembl:ENSP00000503855|ensembl:ENSP00000504035|ensembl:ENSP00000504164	intact:EBI-525291|uniprotkb:Q8WXE7|uniprotkb:Q05CV1|uniprotkb:Q53X86|uniprotkb:Q6P5T2|ensembl:ENSP00000336762|ensembl:ENSP00000381077	psi-mi:anxa2_human(display_long)|uniprotkb:ANXA2(gene name)|psi-mi:ANXA2(display_short)|uniprotkb:ANX2(gene name synonym)|uniprotkb:ANX2L4(gene name synonym)|uniprotkb:CAL1H(gene name synonym)|uniprotkb:LPC2D(gene name synonym)|uniprotkb:Annexin-2(gene name synonym)|uniprotkb:Annexin II(gene name synonym)|uniprotkb:Lipocortin II(gene name synonym)|uniprotkb:Calpactin I heavy chain(gene name synonym)|uniprotkb:Chromobindin-8(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:Protein I(gene name synonym)|uniprotkb:Placental anticoagulant protein IV(gene name synonym)|uniprotkb:Calpactin-1 heavy chain(gene name synonym)	psi-mi:angi_human(display_long)|uniprotkb:Ribonuclease 5(gene name synonym)|uniprotkb:ANG(gene name)|psi-mi:ANG(display_short)|uniprotkb:RNASE5(gene name synonym)	psi-mi:"MI:0813"(proximity ligation assay)	Dutta et al. (2014)	imex:IM-25501|pubmed:24457100	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12513074|imex:IM-25501-25	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001002857.1|refseq:NP_001002858.1|refseq:NP_001129487.1|refseq:NP_004030.1|refseq:XP_016877579.1|refseq:XP_016877580.1|ensembl:ENSG00000182718(gene)|ensembl:ENST00000396024(transcript)|ensembl:ENST00000421017(transcript)|ensembl:ENST00000451270(transcript)|ensembl:ENST00000557906(transcript)|ensembl:ENST00000558558(transcript)|ensembl:ENST00000559818(transcript)|ensembl:ENST00000559956(transcript)|ensembl:ENST00000560468(transcript)|ensembl:ENST00000677968(transcript)|ensembl:ENST00000678061(transcript)|ensembl:ENST00000678450(transcript)|ensembl:ENST00000678870(transcript)|ensembl:ENST00000679109(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001726"(ruffle)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005938"(cell cortex)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0007589"(body fluid secretion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019834"(phospholipase A2 inhibitor activity)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031340"(positive regulation of vesicle fusion)|go:"GO:0031902"(late endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032804"(negative regulation of low-density lipoprotein particle receptor catabolic process)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035749"(myelin sheath adaxonal region)|go:"GO:0036035"(osteoclast development)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0042730"(fibrinolysis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0044090"(positive regulation of vacuole organization)|go:"GO:0044354"(macropinosome)|go:"GO:0044548"(S100 protein binding)|go:"GO:0044730"(bone sialoprotein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046790"(virion binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0005509"(calcium ion binding)|rcsb pdb:2HYU|rcsb pdb:2HYV|rcsb pdb:2HYW|rcsb pdb:4DRW|rcsb pdb:4FTG|rcsb pdb:4HRH|rcsb pdb:5LPU|rcsb pdb:5LPX|rcsb pdb:5LQ0|rcsb pdb:5LQ2|rcsb pdb:5N7D|rcsb pdb:5N7F|rcsb pdb:5N7G|rcsb pdb:6TWQ|rcsb pdb:6TWU|rcsb pdb:6TWX|rcsb pdb:6TWY|reactome:R-HSA-445355|reactome:R-HSA-6798695|reactome:R-HSA-75205|reactome:R-HSA-8950505|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:1905581"(positive regulation of low-density lipoprotein particle clearance)|go:"GO:1905597"(positive regulation of low-density lipoprotein particle receptor binding)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|go:"GO:1905602"(positive regulation of receptor-mediated endocytosis involved in cholesterol transport)|go:"GO:1990665"(AnxA2-p11 complex)|go:"GO:1990667"(PCSK9-AnxA2 complex)|interpro:IPR001464(Annexin)|interpro:IPR002389(Annexin, type II)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P07355|rcsb pdb:1W7B|rcsb pdb:1XJL|go:"GO:0097066"(response to thyroid hormone)	refseq:NP_001091046.1|refseq:NP_001136.1|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0019732"(antifungal humoral response)|go:"GO:0019843"(rRNA binding)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030426"(growth cone)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0032311"(angiogenin-PRI complex)|go:"GO:0032431"(activation of phospholipase A2 activity)|go:"GO:0042277"(peptide binding)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042592"(homeostatic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045087"(innate immune response)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR001427(Pancreatic ribonuclease)|interpro:IPR023411|interpro:IPR023412|interpro:IPR036816|rcsb pdb:1A4Y|rcsb pdb:1ANG|go:"GO:0016078"(tRNA catabolic process)|go:"GO:0016477"(cell migration)|rcsb pdb:1AWZ|rcsb pdb:1B1E|rcsb pdb:1B1I|rcsb pdb:1B1J|rcsb pdb:1GV7|rcsb pdb:1H0D|rcsb pdb:1H52|rcsb pdb:1H53|rcsb pdb:1HBY|rcsb pdb:1K58|rcsb pdb:1K59|rcsb pdb:1K5A|rcsb pdb:1K5B|rcsb pdb:1UN3|rcsb pdb:1UN4|rcsb pdb:1UN5|rcsb pdb:2ANG|rcsb pdb:4AHD|rcsb pdb:4AHE|rcsb pdb:4AHF|rcsb pdb:4AHG|rcsb pdb:4AHH|rcsb pdb:4AHI|rcsb pdb:4AHJ|rcsb pdb:4AHK|rcsb pdb:4AHL|rcsb pdb:4AHM|rcsb pdb:4AHN|rcsb pdb:4AOH|rcsb pdb:4B36|rcsb pdb:5EOP|rcsb pdb:5EPZ|rcsb pdb:5EQO|rcsb pdb:5M9A|rcsb pdb:5M9C|rcsb pdb:5M9G|rcsb pdb:5M9J|rcsb pdb:5M9M|rcsb pdb:5M9P|rcsb pdb:5M9Q|rcsb pdb:5M9R|rcsb pdb:5M9S|rcsb pdb:5M9T|rcsb pdb:5M9V|reactome:R-HSA-418990|reactome:R-HSA-9708296|ensembl:ENSG00000214274(gene)|ensembl:ENST00000336811(transcript)|ensembl:ENST00000397990(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001878"(response to yeast)|go:"GO:0001890"(placenta development)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0003677"(DNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0004540"(ribonuclease activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005507"(copper ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006651"(diacylglycerol biosynthetic process)|go:"GO:0007154"(cell communication)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0008201"(heparin binding)|go:"GO:0009303"(rRNA transcription)|go:"GO:0009725"(response to hormone)|go:"GO:0015629"(actin cytoskeleton)	-	-	-	figure legend:6C-3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-t47d-a18)|taxid:9606(ER- and PR-positive hormone-responsive clone of t47d)	-	2016/07/19	2016/08/24	rogid:jcB4Dt0LFv8YaBUnC2BSTCshveg9606	rogid:CSOTublnrV3DIGJfeyCfT14p8m89606	rigid:7O9WBu8P12ixsDwy0TJZNopjFOE	false	-	-	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:Q03405	uniprotkb:P03950	intact:EBI-716505|uniprotkb:Q12876|uniprotkb:Q15845|uniprotkb:Q16887|uniprotkb:Q6IB52|uniprotkb:Q9BWT0|uniprotkb:Q9NYC8|uniprotkb:Q9UD69|uniprotkb:Q9UEA6|uniprotkb:Q9UM92|uniprotkb:Q9UMV0|uniprotkb:A8K409|ensembl:ENSP00000339328	intact:EBI-525291|uniprotkb:Q8WXE7|uniprotkb:Q05CV1|uniprotkb:Q53X86|uniprotkb:Q6P5T2|ensembl:ENSP00000336762|ensembl:ENSP00000381077	psi-mi:upar_human(display_long)|uniprotkb:Monocyte activation antigen Mo3(gene name synonym)|uniprotkb:PLAUR(gene name)|psi-mi:PLAUR(display_short)|uniprotkb:MO3(gene name synonym)|uniprotkb:UPAR(gene name synonym)	psi-mi:angi_human(display_long)|uniprotkb:Ribonuclease 5(gene name synonym)|uniprotkb:ANG(gene name)|psi-mi:ANG(display_short)|uniprotkb:RNASE5(gene name synonym)	psi-mi:"MI:0813"(proximity ligation assay)	Dutta et al. (2014)	imex:IM-25501|pubmed:24457100	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12513079|imex:IM-25501-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001005376.1|refseq:NP_001005377.1|refseq:NP_002650.1|reactome:R-HSA-162791|reactome:R-HSA-6798695|reactome:R-HSA-75205|rcsb pdb:4QTI|ensembl:ENSG00000011422(gene)|ensembl:ENST00000340093(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006935"(chemotaxis)|go:"GO:0007165"(signal transduction)|go:"GO:0007596"(blood coagulation)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030162"(regulation of proteolysis)|go:"GO:0030377"(urokinase plasminogen activator receptor activity)|go:"GO:0034112"(positive regulation of homotypic cell-cell adhesion)|go:"GO:0035579"(specific granule membrane)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042995"(cell projection)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|go:"GO:0031225"(anchored component of membrane)|go:"GO:2001268"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|interpro:IPR018363|interpro:IPR033084|rcsb pdb:1YWH|rcsb pdb:2FD6|rcsb pdb:2I9B|rcsb pdb:3BT1|rcsb pdb:3BT2|rcsb pdb:3U73|rcsb pdb:3U74|rcsb pdb:4K24|refseq:NP_001287966.1|dip:DIP-137N	refseq:NP_001091046.1|refseq:NP_001136.1|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0019732"(antifungal humoral response)|go:"GO:0019843"(rRNA binding)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030426"(growth cone)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0032311"(angiogenin-PRI complex)|go:"GO:0032431"(activation of phospholipase A2 activity)|go:"GO:0042277"(peptide binding)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042592"(homeostatic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045087"(innate immune response)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR001427(Pancreatic ribonuclease)|interpro:IPR023411|interpro:IPR023412|interpro:IPR036816|rcsb pdb:1A4Y|rcsb pdb:1ANG|go:"GO:0016078"(tRNA catabolic process)|go:"GO:0016477"(cell migration)|rcsb pdb:1AWZ|rcsb pdb:1B1E|rcsb pdb:1B1I|rcsb pdb:1B1J|rcsb pdb:1GV7|rcsb pdb:1H0D|rcsb pdb:1H52|rcsb pdb:1H53|rcsb pdb:1HBY|rcsb pdb:1K58|rcsb pdb:1K59|rcsb pdb:1K5A|rcsb pdb:1K5B|rcsb pdb:1UN3|rcsb pdb:1UN4|rcsb pdb:1UN5|rcsb pdb:2ANG|rcsb pdb:4AHD|rcsb pdb:4AHE|rcsb pdb:4AHF|rcsb pdb:4AHG|rcsb pdb:4AHH|rcsb pdb:4AHI|rcsb pdb:4AHJ|rcsb pdb:4AHK|rcsb pdb:4AHL|rcsb pdb:4AHM|rcsb pdb:4AHN|rcsb pdb:4AOH|rcsb pdb:4B36|rcsb pdb:5EOP|rcsb pdb:5EPZ|rcsb pdb:5EQO|rcsb pdb:5M9A|rcsb pdb:5M9C|rcsb pdb:5M9G|rcsb pdb:5M9J|rcsb pdb:5M9M|rcsb pdb:5M9P|rcsb pdb:5M9Q|rcsb pdb:5M9R|rcsb pdb:5M9S|rcsb pdb:5M9T|rcsb pdb:5M9V|reactome:R-HSA-418990|reactome:R-HSA-9708296|ensembl:ENSG00000214274(gene)|ensembl:ENST00000336811(transcript)|ensembl:ENST00000397990(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001878"(response to yeast)|go:"GO:0001890"(placenta development)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0003677"(DNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0004540"(ribonuclease activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005507"(copper ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006651"(diacylglycerol biosynthetic process)|go:"GO:0007154"(cell communication)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0008201"(heparin binding)|go:"GO:0009303"(rRNA transcription)|go:"GO:0009725"(response to hormone)|go:"GO:0015629"(actin cytoskeleton)	-	-	-	figure legend:6C-1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-t47d-a18)|taxid:9606(ER- and PR-positive hormone-responsive clone of t47d)	-	2016/07/19	2016/08/24	rogid:faxxSUpKpPAaAlPpUpvg2NG4DOA9606	rogid:CSOTublnrV3DIGJfeyCfT14p8m89606	rigid:MoQU+5+dO8o7aWpoudCs4v1TnPQ	false	-	-	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:P00749	uniprotkb:P03950	intact:EBI-3905042|uniprotkb:Q15844|uniprotkb:B4DPZ2|uniprotkb:Q53XS3|uniprotkb:Q16618|uniprotkb:Q5SWW9|uniprotkb:Q969W6|ensembl:ENSP00000361850	intact:EBI-525291|uniprotkb:Q8WXE7|uniprotkb:Q05CV1|uniprotkb:Q53X86|uniprotkb:Q6P5T2|ensembl:ENSP00000336762|ensembl:ENSP00000381077	psi-mi:urok_human(display_long)|uniprotkb:PLAU(gene name)|psi-mi:PLAU(display_short)	psi-mi:angi_human(display_long)|uniprotkb:Ribonuclease 5(gene name synonym)|uniprotkb:ANG(gene name)|psi-mi:ANG(display_short)|uniprotkb:RNASE5(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Dutta et al. (2014)	imex:IM-25501|pubmed:24457100	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12513109|imex:IM-25501-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001138503.1|refseq:NP_002649.1|dip:DIP-46387N|refseq:NP_001306120.1|rcsb pdb:4MNX|rcsb pdb:4MNY|rcsb pdb:4OS1|rcsb pdb:4OS2|rcsb pdb:4OS4|rcsb pdb:4OS5|rcsb pdb:4OS6|rcsb pdb:4OS7|rcsb pdb:4X0W|rcsb pdb:4X1N|rcsb pdb:4X1P|rcsb pdb:4X1Q|rcsb pdb:4X1R|rcsb pdb:4X1S|rcsb pdb:4XSK|rcsb pdb:4ZHL|rcsb pdb:4ZHM|rcsb pdb:4ZKN|rcsb pdb:4ZKO|rcsb pdb:4ZKR|rcsb pdb:4ZKS|ensembl:ENSG00000122861(gene)|ensembl:ENST00000372764(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006508"(proteolysis)|go:"GO:0006935"(chemotaxis)|go:"GO:0007165"(signal transduction)|go:"GO:0007596"(blood coagulation)|go:"GO:0009986"(cell surface)|go:"GO:0010469"(regulation of signaling receptor activity)|go:"GO:0014909"(smooth muscle cell migration)|go:"GO:0014910"(regulation of smooth muscle cell migration)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031639"(plasminogen activation)|go:"GO:0033628"(regulation of cell adhesion mediated by integrin)|go:"GO:0035579"(specific granule membrane)|go:"GO:0042730"(fibrinolysis)|go:"GO:0061041"(regulation of wound healing)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:2000097"(regulation of smooth muscle cell-matrix adhesion)|interpro:IPR000001(Kringle)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR018114|interpro:IPR033116|interpro:IPR034814|interpro:IPR038178|interpro:IPR043504|rcsb pdb:1C5W|rcsb pdb:1C5X|rcsb pdb:1C5Y|rcsb pdb:1C5Z|rcsb pdb:1EJN|rcsb pdb:1F5K|go:"GO:0042127"(regulation of cell population proliferation)|rcsb pdb:1F5L|rcsb pdb:1F92|rcsb pdb:5ZAH|rcsb pdb:5ZAJ|rcsb pdb:5ZC5|rcsb pdb:6AG2|rcsb pdb:6AG3|rcsb pdb:6AG7|rcsb pdb:6AG9|rcsb pdb:6JYP|rcsb pdb:6JYQ|rcsb pdb:6L04|rcsb pdb:6L05|rcsb pdb:6NMB|rcsb pdb:6XVD|reactome:R-HSA-6798695|reactome:R-HSA-75205|rcsb pdb:5HGG|rcsb pdb:5WXF|rcsb pdb:5WXO|rcsb pdb:5WXP|rcsb pdb:5WXQ|rcsb pdb:5WXR|rcsb pdb:5WXS|rcsb pdb:5WXT|rcsb pdb:5XG4|rcsb pdb:5YC6|rcsb pdb:5YC7|rcsb pdb:5Z1C|rcsb pdb:5ZA7|rcsb pdb:5ZA8|rcsb pdb:5ZA9|rcsb pdb:5ZAE|rcsb pdb:5ZAF|rcsb pdb:5ZAG|rcsb pdb:1O5A|rcsb pdb:1O5B|rcsb pdb:1O5C|rcsb pdb:1OWD|rcsb pdb:1OWE|rcsb pdb:1OWH|rcsb pdb:1OWI|rcsb pdb:1OWJ|rcsb pdb:1OWK|rcsb pdb:1SC8|rcsb pdb:1SQA|rcsb pdb:1SQO|rcsb pdb:1SQT|rcsb pdb:1U6Q|rcsb pdb:1URK|rcsb pdb:1VJ9|rcsb pdb:1VJA|rcsb pdb:1W0Z|rcsb pdb:1W10|rcsb pdb:1W11|rcsb pdb:1W12|rcsb pdb:1W13|rcsb pdb:1W14|rcsb pdb:1FV9|rcsb pdb:1GI7|rcsb pdb:1GI8|rcsb pdb:1GI9|rcsb pdb:1GJ7|rcsb pdb:1GJ8|rcsb pdb:1GJ9|rcsb pdb:1GJA|rcsb pdb:1GJB|rcsb pdb:1GJC|rcsb pdb:1GJD|rcsb pdb:1KDU|rcsb pdb:1LMW|rcsb pdb:1O3P|rcsb pdb:2FD6|rcsb pdb:2I9A|rcsb pdb:2I9B|rcsb pdb:2NWN|rcsb pdb:2O8T|rcsb pdb:2O8U|rcsb pdb:2O8W|rcsb pdb:2R2W|rcsb pdb:2VIN|rcsb pdb:2VIO|rcsb pdb:2VIP|rcsb pdb:2VIQ|rcsb pdb:2VIV|rcsb pdb:2VIW|rcsb pdb:2VNT|rcsb pdb:3BT1|rcsb pdb:3BT2|rcsb pdb:3IG6|rcsb pdb:3KGP|rcsb pdb:3KHV|rcsb pdb:3KID|rcsb pdb:3M61|rcsb pdb:3MHW|rcsb pdb:3MWI|rcsb pdb:3OX7|rcsb pdb:3OY5|rcsb pdb:3OY6|rcsb pdb:3PB1|rcsb pdb:3QN7|rcsb pdb:3U73|rcsb pdb:4DVA|rcsb pdb:4DW2|rcsb pdb:4FU7|rcsb pdb:4FU8|rcsb pdb:4FU9|rcsb pdb:4FUB|rcsb pdb:4FUC|rcsb pdb:4FUD|rcsb pdb:4FUE|rcsb pdb:4FUF|rcsb pdb:4FUG|rcsb pdb:4FUH|rcsb pdb:4FUI|rcsb pdb:4FUJ|rcsb pdb:4GLY|rcsb pdb:4H42|rcsb pdb:4JK5|rcsb pdb:4JK6|rcsb pdb:4K24|rcsb pdb:4MNV|rcsb pdb:4MNW	refseq:NP_001091046.1|refseq:NP_001136.1|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0019732"(antifungal humoral response)|go:"GO:0019843"(rRNA binding)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030426"(growth cone)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0032311"(angiogenin-PRI complex)|go:"GO:0032431"(activation of phospholipase A2 activity)|go:"GO:0042277"(peptide binding)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042592"(homeostatic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045087"(innate immune response)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR001427(Pancreatic ribonuclease)|interpro:IPR023411|interpro:IPR023412|interpro:IPR036816|rcsb pdb:1A4Y|rcsb pdb:1ANG|go:"GO:0016078"(tRNA catabolic process)|go:"GO:0016477"(cell migration)|rcsb pdb:1AWZ|rcsb pdb:1B1E|rcsb pdb:1B1I|rcsb pdb:1B1J|rcsb pdb:1GV7|rcsb pdb:1H0D|rcsb pdb:1H52|rcsb pdb:1H53|rcsb pdb:1HBY|rcsb pdb:1K58|rcsb pdb:1K59|rcsb pdb:1K5A|rcsb pdb:1K5B|rcsb pdb:1UN3|rcsb pdb:1UN4|rcsb pdb:1UN5|rcsb pdb:2ANG|rcsb pdb:4AHD|rcsb pdb:4AHE|rcsb pdb:4AHF|rcsb pdb:4AHG|rcsb pdb:4AHH|rcsb pdb:4AHI|rcsb pdb:4AHJ|rcsb pdb:4AHK|rcsb pdb:4AHL|rcsb pdb:4AHM|rcsb pdb:4AHN|rcsb pdb:4AOH|rcsb pdb:4B36|rcsb pdb:5EOP|rcsb pdb:5EPZ|rcsb pdb:5EQO|rcsb pdb:5M9A|rcsb pdb:5M9C|rcsb pdb:5M9G|rcsb pdb:5M9J|rcsb pdb:5M9M|rcsb pdb:5M9P|rcsb pdb:5M9Q|rcsb pdb:5M9R|rcsb pdb:5M9S|rcsb pdb:5M9T|rcsb pdb:5M9V|reactome:R-HSA-418990|reactome:R-HSA-9708296|ensembl:ENSG00000214274(gene)|ensembl:ENST00000336811(transcript)|ensembl:ENST00000397990(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001878"(response to yeast)|go:"GO:0001890"(placenta development)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0003677"(DNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0004540"(ribonuclease activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005507"(copper ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006651"(diacylglycerol biosynthetic process)|go:"GO:0007154"(cell communication)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0008201"(heparin binding)|go:"GO:0009303"(rRNA transcription)|go:"GO:0009725"(response to hormone)|go:"GO:0015629"(actin cytoskeleton)	-	-	-	figure legend:11A, 13D|comment:The addition of recombinant ANG restores the interaction lost in ANG-/- cells.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-mda_mb_231)|taxid:9606(Homo sapiens Caucasian breast adenocarcinoma)	-	2016/07/19	2016/08/24	rogid:UgdiI+n26oe/Pa7q8Le493SlNE89606	rogid:CSOTublnrV3DIGJfeyCfT14p8m89606	rigid:Ko238EFc/mxw0OFQ6gM9BXpdGc0	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P00749	uniprotkb:Q03405	intact:EBI-3905042|uniprotkb:Q15844|uniprotkb:B4DPZ2|uniprotkb:Q53XS3|uniprotkb:Q16618|uniprotkb:Q5SWW9|uniprotkb:Q969W6|ensembl:ENSP00000361850	intact:EBI-716505|uniprotkb:Q12876|uniprotkb:Q15845|uniprotkb:Q16887|uniprotkb:Q6IB52|uniprotkb:Q9BWT0|uniprotkb:Q9NYC8|uniprotkb:Q9UD69|uniprotkb:Q9UEA6|uniprotkb:Q9UM92|uniprotkb:Q9UMV0|uniprotkb:A8K409|ensembl:ENSP00000339328	psi-mi:urok_human(display_long)|uniprotkb:PLAU(gene name)|psi-mi:PLAU(display_short)	psi-mi:upar_human(display_long)|uniprotkb:Monocyte activation antigen Mo3(gene name synonym)|uniprotkb:PLAUR(gene name)|psi-mi:PLAUR(display_short)|uniprotkb:MO3(gene name synonym)|uniprotkb:UPAR(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Dutta et al. (2014)	imex:IM-25501|pubmed:24457100	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12513109|imex:IM-25501-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001138503.1|refseq:NP_002649.1|dip:DIP-46387N|refseq:NP_001306120.1|rcsb pdb:4MNX|rcsb pdb:4MNY|rcsb pdb:4OS1|rcsb pdb:4OS2|rcsb pdb:4OS4|rcsb pdb:4OS5|rcsb pdb:4OS6|rcsb pdb:4OS7|rcsb pdb:4X0W|rcsb pdb:4X1N|rcsb pdb:4X1P|rcsb pdb:4X1Q|rcsb pdb:4X1R|rcsb pdb:4X1S|rcsb pdb:4XSK|rcsb pdb:4ZHL|rcsb pdb:4ZHM|rcsb pdb:4ZKN|rcsb pdb:4ZKO|rcsb pdb:4ZKR|rcsb pdb:4ZKS|ensembl:ENSG00000122861(gene)|ensembl:ENST00000372764(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006508"(proteolysis)|go:"GO:0006935"(chemotaxis)|go:"GO:0007165"(signal transduction)|go:"GO:0007596"(blood coagulation)|go:"GO:0009986"(cell surface)|go:"GO:0010469"(regulation of signaling receptor activity)|go:"GO:0014909"(smooth muscle cell migration)|go:"GO:0014910"(regulation of smooth muscle cell migration)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031639"(plasminogen activation)|go:"GO:0033628"(regulation of cell adhesion mediated by integrin)|go:"GO:0035579"(specific granule membrane)|go:"GO:0042730"(fibrinolysis)|go:"GO:0061041"(regulation of wound healing)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:2000097"(regulation of smooth muscle cell-matrix adhesion)|interpro:IPR000001(Kringle)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR018114|interpro:IPR033116|interpro:IPR034814|interpro:IPR038178|interpro:IPR043504|rcsb pdb:1C5W|rcsb pdb:1C5X|rcsb pdb:1C5Y|rcsb pdb:1C5Z|rcsb pdb:1EJN|rcsb pdb:1F5K|go:"GO:0042127"(regulation of cell population proliferation)|rcsb pdb:1F5L|rcsb pdb:1F92|rcsb pdb:5ZAH|rcsb pdb:5ZAJ|rcsb pdb:5ZC5|rcsb pdb:6AG2|rcsb pdb:6AG3|rcsb pdb:6AG7|rcsb pdb:6AG9|rcsb pdb:6JYP|rcsb pdb:6JYQ|rcsb pdb:6L04|rcsb pdb:6L05|rcsb pdb:6NMB|rcsb pdb:6XVD|reactome:R-HSA-6798695|reactome:R-HSA-75205|rcsb pdb:5HGG|rcsb pdb:5WXF|rcsb pdb:5WXO|rcsb pdb:5WXP|rcsb pdb:5WXQ|rcsb pdb:5WXR|rcsb pdb:5WXS|rcsb pdb:5WXT|rcsb pdb:5XG4|rcsb pdb:5YC6|rcsb pdb:5YC7|rcsb pdb:5Z1C|rcsb pdb:5ZA7|rcsb pdb:5ZA8|rcsb pdb:5ZA9|rcsb pdb:5ZAE|rcsb pdb:5ZAF|rcsb pdb:5ZAG|rcsb pdb:1O5A|rcsb pdb:1O5B|rcsb pdb:1O5C|rcsb pdb:1OWD|rcsb pdb:1OWE|rcsb pdb:1OWH|rcsb pdb:1OWI|rcsb pdb:1OWJ|rcsb pdb:1OWK|rcsb pdb:1SC8|rcsb pdb:1SQA|rcsb pdb:1SQO|rcsb pdb:1SQT|rcsb pdb:1U6Q|rcsb pdb:1URK|rcsb pdb:1VJ9|rcsb pdb:1VJA|rcsb pdb:1W0Z|rcsb pdb:1W10|rcsb pdb:1W11|rcsb pdb:1W12|rcsb pdb:1W13|rcsb pdb:1W14|rcsb pdb:1FV9|rcsb pdb:1GI7|rcsb pdb:1GI8|rcsb pdb:1GI9|rcsb pdb:1GJ7|rcsb pdb:1GJ8|rcsb pdb:1GJ9|rcsb pdb:1GJA|rcsb pdb:1GJB|rcsb pdb:1GJC|rcsb pdb:1GJD|rcsb pdb:1KDU|rcsb pdb:1LMW|rcsb pdb:1O3P|rcsb pdb:2FD6|rcsb pdb:2I9A|rcsb pdb:2I9B|rcsb pdb:2NWN|rcsb pdb:2O8T|rcsb pdb:2O8U|rcsb pdb:2O8W|rcsb pdb:2R2W|rcsb pdb:2VIN|rcsb pdb:2VIO|rcsb pdb:2VIP|rcsb pdb:2VIQ|rcsb pdb:2VIV|rcsb pdb:2VIW|rcsb pdb:2VNT|rcsb pdb:3BT1|rcsb pdb:3BT2|rcsb pdb:3IG6|rcsb pdb:3KGP|rcsb pdb:3KHV|rcsb pdb:3KID|rcsb pdb:3M61|rcsb pdb:3MHW|rcsb pdb:3MWI|rcsb pdb:3OX7|rcsb pdb:3OY5|rcsb pdb:3OY6|rcsb pdb:3PB1|rcsb pdb:3QN7|rcsb pdb:3U73|rcsb pdb:4DVA|rcsb pdb:4DW2|rcsb pdb:4FU7|rcsb pdb:4FU8|rcsb pdb:4FU9|rcsb pdb:4FUB|rcsb pdb:4FUC|rcsb pdb:4FUD|rcsb pdb:4FUE|rcsb pdb:4FUF|rcsb pdb:4FUG|rcsb pdb:4FUH|rcsb pdb:4FUI|rcsb pdb:4FUJ|rcsb pdb:4GLY|rcsb pdb:4H42|rcsb pdb:4JK5|rcsb pdb:4JK6|rcsb pdb:4K24|rcsb pdb:4MNV|rcsb pdb:4MNW	refseq:NP_001005376.1|refseq:NP_001005377.1|refseq:NP_002650.1|reactome:R-HSA-162791|reactome:R-HSA-6798695|reactome:R-HSA-75205|rcsb pdb:4QTI|ensembl:ENSG00000011422(gene)|ensembl:ENST00000340093(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006935"(chemotaxis)|go:"GO:0007165"(signal transduction)|go:"GO:0007596"(blood coagulation)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030162"(regulation of proteolysis)|go:"GO:0030377"(urokinase plasminogen activator receptor activity)|go:"GO:0034112"(positive regulation of homotypic cell-cell adhesion)|go:"GO:0035579"(specific granule membrane)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042995"(cell projection)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|go:"GO:0031225"(anchored component of membrane)|go:"GO:2001268"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|interpro:IPR018363|interpro:IPR033084|rcsb pdb:1YWH|rcsb pdb:2FD6|rcsb pdb:2I9B|rcsb pdb:3BT1|rcsb pdb:3BT2|rcsb pdb:3U73|rcsb pdb:3U74|rcsb pdb:4K24|refseq:NP_001287966.1|dip:DIP-137N	-	-	-	figure legend:11A, 13D|comment:The addition of recombinant ANG restores the interaction lost in ANG-/- cells.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-mda_mb_231)|taxid:9606(Homo sapiens Caucasian breast adenocarcinoma)	-	2016/07/19	2016/08/24	rogid:UgdiI+n26oe/Pa7q8Le493SlNE89606	rogid:faxxSUpKpPAaAlPpUpvg2NG4DOA9606	rigid:Ko238EFc/mxw0OFQ6gM9BXpdGc0	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P60903	uniprotkb:P03950	intact:EBI-717048|uniprotkb:P08206|uniprotkb:Q5T1C5|uniprotkb:A8K4V8|ensembl:ENSP00000357799|ensembl:ENSP00000357801	intact:EBI-525291|uniprotkb:Q8WXE7|uniprotkb:Q05CV1|uniprotkb:Q53X86|uniprotkb:Q6P5T2|ensembl:ENSP00000336762|ensembl:ENSP00000381077	psi-mi:s10aa_human(display_long)|uniprotkb:S100 calcium-binding protein A10(gene name synonym)|uniprotkb:Calpactin-1 light chain(gene name synonym)|uniprotkb:Calpactin I light chain(gene name synonym)|uniprotkb:p10 protein(gene name synonym)|uniprotkb:p11(gene name synonym)|uniprotkb:Cellular ligand of annexin II(gene name synonym)|uniprotkb:S100A10(gene name)|psi-mi:S100A10(display_short)|uniprotkb:ANX2LG(gene name synonym)|uniprotkb:CAL1L(gene name synonym)|uniprotkb:CLP11(gene name synonym)	psi-mi:angi_human(display_long)|uniprotkb:Ribonuclease 5(gene name synonym)|uniprotkb:ANG(gene name)|psi-mi:ANG(display_short)|uniprotkb:RNASE5(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Dutta et al. (2014)	imex:IM-25501|pubmed:24457100	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12513152|imex:IM-25501-27	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002957.1|ensembl:ENSG00000197747(gene)|ensembl:ENST00000368809(transcript)|ensembl:ENST00000368811(transcript)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0005576"(extracellular region)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0042493"|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1990665"(AnxA2-p11 complex)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR028476|rcsb pdb:1A4P|rcsb pdb:1BT6|rcsb pdb:4DRW|rcsb pdb:4FTG|rcsb pdb:4HRE|rcsb pdb:4HRG|rcsb pdb:4HRH|reactome:R-HSA-75205	refseq:NP_001091046.1|refseq:NP_001136.1|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0019732"(antifungal humoral response)|go:"GO:0019843"(rRNA binding)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030426"(growth cone)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0032311"(angiogenin-PRI complex)|go:"GO:0032431"(activation of phospholipase A2 activity)|go:"GO:0042277"(peptide binding)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042592"(homeostatic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045087"(innate immune response)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR001427(Pancreatic ribonuclease)|interpro:IPR023411|interpro:IPR023412|interpro:IPR036816|rcsb pdb:1A4Y|rcsb pdb:1ANG|go:"GO:0016078"(tRNA catabolic process)|go:"GO:0016477"(cell migration)|rcsb pdb:1AWZ|rcsb pdb:1B1E|rcsb pdb:1B1I|rcsb pdb:1B1J|rcsb pdb:1GV7|rcsb pdb:1H0D|rcsb pdb:1H52|rcsb pdb:1H53|rcsb pdb:1HBY|rcsb pdb:1K58|rcsb pdb:1K59|rcsb pdb:1K5A|rcsb pdb:1K5B|rcsb pdb:1UN3|rcsb pdb:1UN4|rcsb pdb:1UN5|rcsb pdb:2ANG|rcsb pdb:4AHD|rcsb pdb:4AHE|rcsb pdb:4AHF|rcsb pdb:4AHG|rcsb pdb:4AHH|rcsb pdb:4AHI|rcsb pdb:4AHJ|rcsb pdb:4AHK|rcsb pdb:4AHL|rcsb pdb:4AHM|rcsb pdb:4AHN|rcsb pdb:4AOH|rcsb pdb:4B36|rcsb pdb:5EOP|rcsb pdb:5EPZ|rcsb pdb:5EQO|rcsb pdb:5M9A|rcsb pdb:5M9C|rcsb pdb:5M9G|rcsb pdb:5M9J|rcsb pdb:5M9M|rcsb pdb:5M9P|rcsb pdb:5M9Q|rcsb pdb:5M9R|rcsb pdb:5M9S|rcsb pdb:5M9T|rcsb pdb:5M9V|reactome:R-HSA-418990|reactome:R-HSA-9708296|ensembl:ENSG00000214274(gene)|ensembl:ENST00000336811(transcript)|ensembl:ENST00000397990(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001878"(response to yeast)|go:"GO:0001890"(placenta development)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0003677"(DNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0004540"(ribonuclease activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005507"(copper ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006651"(diacylglycerol biosynthetic process)|go:"GO:0007154"(cell communication)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0008201"(heparin binding)|go:"GO:0009303"(rRNA transcription)|go:"GO:0009725"(response to hormone)|go:"GO:0015629"(actin cytoskeleton)	-	-	-	figure legend:3B,4B, 4C.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-t47d-a18)|taxid:9606(ER- and PR-positive hormone-responsive clone of t47d)	-	2016/07/19	2016/08/24	rogid:WlxwW4qaHp6tcyEAYvQ2ut9SyRA9606	rogid:CSOTublnrV3DIGJfeyCfT14p8m89606	rigid:9Xf/xc8o3UvT8j61sO1tnaJwn84	false	-	-	-	-	psi-mi:"MI:1200"(immunocytochemistry)	psi-mi:"MI:1200"(immunocytochemistry)
uniprotkb:P03950	uniprotkb:P07355	intact:EBI-525291|uniprotkb:Q8WXE7|uniprotkb:Q05CV1|uniprotkb:Q53X86|uniprotkb:Q6P5T2|ensembl:ENSP00000336762|ensembl:ENSP00000381077	intact:EBI-352622|uniprotkb:Q567R4|uniprotkb:Q96DD5|intact:EBI-2211824|uniprotkb:Q6N0B3|uniprotkb:Q8TBV2|uniprotkb:Q9UDH8|ensembl:ENSP00000379342|ensembl:ENSP00000387545|ensembl:ENSP00000411352|ensembl:ENSP00000452858|ensembl:ENSP00000452895|ensembl:ENSP00000452981|ensembl:ENSP00000453694|ensembl:ENSP00000453859|ensembl:ENSP00000503447|ensembl:ENSP00000503757|ensembl:ENSP00000503855|ensembl:ENSP00000504035|ensembl:ENSP00000504164	psi-mi:angi_human(display_long)|uniprotkb:Ribonuclease 5(gene name synonym)|uniprotkb:ANG(gene name)|psi-mi:ANG(display_short)|uniprotkb:RNASE5(gene name synonym)	psi-mi:anxa2_human(display_long)|uniprotkb:ANXA2(gene name)|psi-mi:ANXA2(display_short)|uniprotkb:ANX2(gene name synonym)|uniprotkb:ANX2L4(gene name synonym)|uniprotkb:CAL1H(gene name synonym)|uniprotkb:LPC2D(gene name synonym)|uniprotkb:Annexin-2(gene name synonym)|uniprotkb:Annexin II(gene name synonym)|uniprotkb:Lipocortin II(gene name synonym)|uniprotkb:Calpactin I heavy chain(gene name synonym)|uniprotkb:Chromobindin-8(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:Protein I(gene name synonym)|uniprotkb:Placental anticoagulant protein IV(gene name synonym)|uniprotkb:Calpactin-1 heavy chain(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Dutta et al. (2014)	imex:IM-25501|pubmed:24457100	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12513164|imex:IM-25501-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001091046.1|refseq:NP_001136.1|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0019732"(antifungal humoral response)|go:"GO:0019843"(rRNA binding)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030426"(growth cone)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0032311"(angiogenin-PRI complex)|go:"GO:0032431"(activation of phospholipase A2 activity)|go:"GO:0042277"(peptide binding)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042592"(homeostatic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045087"(innate immune response)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR001427(Pancreatic ribonuclease)|interpro:IPR023411|interpro:IPR023412|interpro:IPR036816|rcsb pdb:1A4Y|rcsb pdb:1ANG|go:"GO:0016078"(tRNA catabolic process)|go:"GO:0016477"(cell migration)|rcsb pdb:1AWZ|rcsb pdb:1B1E|rcsb pdb:1B1I|rcsb pdb:1B1J|rcsb pdb:1GV7|rcsb pdb:1H0D|rcsb pdb:1H52|rcsb pdb:1H53|rcsb pdb:1HBY|rcsb pdb:1K58|rcsb pdb:1K59|rcsb pdb:1K5A|rcsb pdb:1K5B|rcsb pdb:1UN3|rcsb pdb:1UN4|rcsb pdb:1UN5|rcsb pdb:2ANG|rcsb pdb:4AHD|rcsb pdb:4AHE|rcsb pdb:4AHF|rcsb pdb:4AHG|rcsb pdb:4AHH|rcsb pdb:4AHI|rcsb pdb:4AHJ|rcsb pdb:4AHK|rcsb pdb:4AHL|rcsb pdb:4AHM|rcsb pdb:4AHN|rcsb pdb:4AOH|rcsb pdb:4B36|rcsb pdb:5EOP|rcsb pdb:5EPZ|rcsb pdb:5EQO|rcsb pdb:5M9A|rcsb pdb:5M9C|rcsb pdb:5M9G|rcsb pdb:5M9J|rcsb pdb:5M9M|rcsb pdb:5M9P|rcsb pdb:5M9Q|rcsb pdb:5M9R|rcsb pdb:5M9S|rcsb pdb:5M9T|rcsb pdb:5M9V|reactome:R-HSA-418990|reactome:R-HSA-9708296|ensembl:ENSG00000214274(gene)|ensembl:ENST00000336811(transcript)|ensembl:ENST00000397990(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001878"(response to yeast)|go:"GO:0001890"(placenta development)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0003677"(DNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0004540"(ribonuclease activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005507"(copper ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006651"(diacylglycerol biosynthetic process)|go:"GO:0007154"(cell communication)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0008201"(heparin binding)|go:"GO:0009303"(rRNA transcription)|go:"GO:0009725"(response to hormone)|go:"GO:0015629"(actin cytoskeleton)	refseq:NP_001002857.1|refseq:NP_001002858.1|refseq:NP_001129487.1|refseq:NP_004030.1|refseq:XP_016877579.1|refseq:XP_016877580.1|ensembl:ENSG00000182718(gene)|ensembl:ENST00000396024(transcript)|ensembl:ENST00000421017(transcript)|ensembl:ENST00000451270(transcript)|ensembl:ENST00000557906(transcript)|ensembl:ENST00000558558(transcript)|ensembl:ENST00000559818(transcript)|ensembl:ENST00000559956(transcript)|ensembl:ENST00000560468(transcript)|ensembl:ENST00000677968(transcript)|ensembl:ENST00000678061(transcript)|ensembl:ENST00000678450(transcript)|ensembl:ENST00000678870(transcript)|ensembl:ENST00000679109(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001726"(ruffle)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005938"(cell cortex)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0007589"(body fluid secretion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019834"(phospholipase A2 inhibitor activity)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031340"(positive regulation of vesicle fusion)|go:"GO:0031902"(late endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032804"(negative regulation of low-density lipoprotein particle receptor catabolic process)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035749"(myelin sheath adaxonal region)|go:"GO:0036035"(osteoclast development)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0042730"(fibrinolysis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0044090"(positive regulation of vacuole organization)|go:"GO:0044354"(macropinosome)|go:"GO:0044548"(S100 protein binding)|go:"GO:0044730"(bone sialoprotein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046790"(virion binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0005509"(calcium ion binding)|rcsb pdb:2HYU|rcsb pdb:2HYV|rcsb pdb:2HYW|rcsb pdb:4DRW|rcsb pdb:4FTG|rcsb pdb:4HRH|rcsb pdb:5LPU|rcsb pdb:5LPX|rcsb pdb:5LQ0|rcsb pdb:5LQ2|rcsb pdb:5N7D|rcsb pdb:5N7F|rcsb pdb:5N7G|rcsb pdb:6TWQ|rcsb pdb:6TWU|rcsb pdb:6TWX|rcsb pdb:6TWY|reactome:R-HSA-445355|reactome:R-HSA-6798695|reactome:R-HSA-75205|reactome:R-HSA-8950505|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:1905581"(positive regulation of low-density lipoprotein particle clearance)|go:"GO:1905597"(positive regulation of low-density lipoprotein particle receptor binding)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|go:"GO:1905602"(positive regulation of receptor-mediated endocytosis involved in cholesterol transport)|go:"GO:1990665"(AnxA2-p11 complex)|go:"GO:1990667"(PCSK9-AnxA2 complex)|interpro:IPR001464(Annexin)|interpro:IPR002389(Annexin, type II)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P07355|rcsb pdb:1W7B|rcsb pdb:1XJL|go:"GO:0097066"(response to thyroid hormone)	-	-	-	figure legend:4B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-t47d-a18)|taxid:9606(ER- and PR-positive hormone-responsive clone of t47d)	-	2016/07/19	2016/08/24	rogid:CSOTublnrV3DIGJfeyCfT14p8m89606	rogid:jcB4Dt0LFv8YaBUnC2BSTCshveg9606	rigid:oOtMjSYR+6rpqn+rDLfskQBRRZs	false	-	-	-	-	psi-mi:"MI:1200"(immunocytochemistry)	psi-mi:"MI:1200"(immunocytochemistry)
uniprotkb:P03950	uniprotkb:P60903	intact:EBI-525291|uniprotkb:Q8WXE7|uniprotkb:Q05CV1|uniprotkb:Q53X86|uniprotkb:Q6P5T2|ensembl:ENSP00000336762|ensembl:ENSP00000381077	intact:EBI-717048|uniprotkb:P08206|uniprotkb:Q5T1C5|uniprotkb:A8K4V8|ensembl:ENSP00000357799|ensembl:ENSP00000357801	psi-mi:angi_human(display_long)|uniprotkb:Ribonuclease 5(gene name synonym)|uniprotkb:ANG(gene name)|psi-mi:ANG(display_short)|uniprotkb:RNASE5(gene name synonym)	psi-mi:s10aa_human(display_long)|uniprotkb:S100 calcium-binding protein A10(gene name synonym)|uniprotkb:Calpactin-1 light chain(gene name synonym)|uniprotkb:Calpactin I light chain(gene name synonym)|uniprotkb:p10 protein(gene name synonym)|uniprotkb:p11(gene name synonym)|uniprotkb:Cellular ligand of annexin II(gene name synonym)|uniprotkb:S100A10(gene name)|psi-mi:S100A10(display_short)|uniprotkb:ANX2LG(gene name synonym)|uniprotkb:CAL1L(gene name synonym)|uniprotkb:CLP11(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Dutta et al. (2014)	imex:IM-25501|pubmed:24457100	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12513164|imex:IM-25501-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001091046.1|refseq:NP_001136.1|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0019732"(antifungal humoral response)|go:"GO:0019843"(rRNA binding)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030426"(growth cone)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0032311"(angiogenin-PRI complex)|go:"GO:0032431"(activation of phospholipase A2 activity)|go:"GO:0042277"(peptide binding)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042592"(homeostatic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045087"(innate immune response)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR001427(Pancreatic ribonuclease)|interpro:IPR023411|interpro:IPR023412|interpro:IPR036816|rcsb pdb:1A4Y|rcsb pdb:1ANG|go:"GO:0016078"(tRNA catabolic process)|go:"GO:0016477"(cell migration)|rcsb pdb:1AWZ|rcsb pdb:1B1E|rcsb pdb:1B1I|rcsb pdb:1B1J|rcsb pdb:1GV7|rcsb pdb:1H0D|rcsb pdb:1H52|rcsb pdb:1H53|rcsb pdb:1HBY|rcsb pdb:1K58|rcsb pdb:1K59|rcsb pdb:1K5A|rcsb pdb:1K5B|rcsb pdb:1UN3|rcsb pdb:1UN4|rcsb pdb:1UN5|rcsb pdb:2ANG|rcsb pdb:4AHD|rcsb pdb:4AHE|rcsb pdb:4AHF|rcsb pdb:4AHG|rcsb pdb:4AHH|rcsb pdb:4AHI|rcsb pdb:4AHJ|rcsb pdb:4AHK|rcsb pdb:4AHL|rcsb pdb:4AHM|rcsb pdb:4AHN|rcsb pdb:4AOH|rcsb pdb:4B36|rcsb pdb:5EOP|rcsb pdb:5EPZ|rcsb pdb:5EQO|rcsb pdb:5M9A|rcsb pdb:5M9C|rcsb pdb:5M9G|rcsb pdb:5M9J|rcsb pdb:5M9M|rcsb pdb:5M9P|rcsb pdb:5M9Q|rcsb pdb:5M9R|rcsb pdb:5M9S|rcsb pdb:5M9T|rcsb pdb:5M9V|reactome:R-HSA-418990|reactome:R-HSA-9708296|ensembl:ENSG00000214274(gene)|ensembl:ENST00000336811(transcript)|ensembl:ENST00000397990(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001878"(response to yeast)|go:"GO:0001890"(placenta development)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0003677"(DNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0004540"(ribonuclease activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005507"(copper ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006651"(diacylglycerol biosynthetic process)|go:"GO:0007154"(cell communication)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0008201"(heparin binding)|go:"GO:0009303"(rRNA transcription)|go:"GO:0009725"(response to hormone)|go:"GO:0015629"(actin cytoskeleton)	refseq:NP_002957.1|ensembl:ENSG00000197747(gene)|ensembl:ENST00000368809(transcript)|ensembl:ENST00000368811(transcript)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0005576"(extracellular region)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0042493"|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1990665"(AnxA2-p11 complex)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR028476|rcsb pdb:1A4P|rcsb pdb:1BT6|rcsb pdb:4DRW|rcsb pdb:4FTG|rcsb pdb:4HRE|rcsb pdb:4HRG|rcsb pdb:4HRH|reactome:R-HSA-75205	-	-	-	figure legend:4B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-t47d-a18)|taxid:9606(ER- and PR-positive hormone-responsive clone of t47d)	-	2016/07/19	2016/08/24	rogid:CSOTublnrV3DIGJfeyCfT14p8m89606	rogid:WlxwW4qaHp6tcyEAYvQ2ut9SyRA9606	rigid:oOtMjSYR+6rpqn+rDLfskQBRRZs	false	-	-	-	-	psi-mi:"MI:1200"(immunocytochemistry)	psi-mi:"MI:1200"(immunocytochemistry)
uniprotkb:P07355	uniprotkb:P03950	intact:EBI-352622|uniprotkb:Q567R4|uniprotkb:Q96DD5|intact:EBI-2211824|uniprotkb:Q6N0B3|uniprotkb:Q8TBV2|uniprotkb:Q9UDH8|ensembl:ENSP00000379342|ensembl:ENSP00000387545|ensembl:ENSP00000411352|ensembl:ENSP00000452858|ensembl:ENSP00000452895|ensembl:ENSP00000452981|ensembl:ENSP00000453694|ensembl:ENSP00000453859|ensembl:ENSP00000503447|ensembl:ENSP00000503757|ensembl:ENSP00000503855|ensembl:ENSP00000504035|ensembl:ENSP00000504164	intact:EBI-525291|uniprotkb:Q8WXE7|uniprotkb:Q05CV1|uniprotkb:Q53X86|uniprotkb:Q6P5T2|ensembl:ENSP00000336762|ensembl:ENSP00000381077	psi-mi:anxa2_human(display_long)|uniprotkb:ANXA2(gene name)|psi-mi:ANXA2(display_short)|uniprotkb:ANX2(gene name synonym)|uniprotkb:ANX2L4(gene name synonym)|uniprotkb:CAL1H(gene name synonym)|uniprotkb:LPC2D(gene name synonym)|uniprotkb:Annexin-2(gene name synonym)|uniprotkb:Annexin II(gene name synonym)|uniprotkb:Lipocortin II(gene name synonym)|uniprotkb:Calpactin I heavy chain(gene name synonym)|uniprotkb:Chromobindin-8(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:Protein I(gene name synonym)|uniprotkb:Placental anticoagulant protein IV(gene name synonym)|uniprotkb:Calpactin-1 heavy chain(gene name synonym)	psi-mi:angi_human(display_long)|uniprotkb:Ribonuclease 5(gene name synonym)|uniprotkb:ANG(gene name)|psi-mi:ANG(display_short)|uniprotkb:RNASE5(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Dutta et al. (2014)	imex:IM-25501|pubmed:24457100	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12513171|imex:IM-25501-31	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001002857.1|refseq:NP_001002858.1|refseq:NP_001129487.1|refseq:NP_004030.1|refseq:XP_016877579.1|refseq:XP_016877580.1|ensembl:ENSG00000182718(gene)|ensembl:ENST00000396024(transcript)|ensembl:ENST00000421017(transcript)|ensembl:ENST00000451270(transcript)|ensembl:ENST00000557906(transcript)|ensembl:ENST00000558558(transcript)|ensembl:ENST00000559818(transcript)|ensembl:ENST00000559956(transcript)|ensembl:ENST00000560468(transcript)|ensembl:ENST00000677968(transcript)|ensembl:ENST00000678061(transcript)|ensembl:ENST00000678450(transcript)|ensembl:ENST00000678870(transcript)|ensembl:ENST00000679109(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001726"(ruffle)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005938"(cell cortex)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0007589"(body fluid secretion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019834"(phospholipase A2 inhibitor activity)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031340"(positive regulation of vesicle fusion)|go:"GO:0031902"(late endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032804"(negative regulation of low-density lipoprotein particle receptor catabolic process)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035749"(myelin sheath adaxonal region)|go:"GO:0036035"(osteoclast development)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0042730"(fibrinolysis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0044090"(positive regulation of vacuole organization)|go:"GO:0044354"(macropinosome)|go:"GO:0044548"(S100 protein binding)|go:"GO:0044730"(bone sialoprotein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046790"(virion binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0005509"(calcium ion binding)|rcsb pdb:2HYU|rcsb pdb:2HYV|rcsb pdb:2HYW|rcsb pdb:4DRW|rcsb pdb:4FTG|rcsb pdb:4HRH|rcsb pdb:5LPU|rcsb pdb:5LPX|rcsb pdb:5LQ0|rcsb pdb:5LQ2|rcsb pdb:5N7D|rcsb pdb:5N7F|rcsb pdb:5N7G|rcsb pdb:6TWQ|rcsb pdb:6TWU|rcsb pdb:6TWX|rcsb pdb:6TWY|reactome:R-HSA-445355|reactome:R-HSA-6798695|reactome:R-HSA-75205|reactome:R-HSA-8950505|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:1905581"(positive regulation of low-density lipoprotein particle clearance)|go:"GO:1905597"(positive regulation of low-density lipoprotein particle receptor binding)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|go:"GO:1905602"(positive regulation of receptor-mediated endocytosis involved in cholesterol transport)|go:"GO:1990665"(AnxA2-p11 complex)|go:"GO:1990667"(PCSK9-AnxA2 complex)|interpro:IPR001464(Annexin)|interpro:IPR002389(Annexin, type II)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P07355|rcsb pdb:1W7B|rcsb pdb:1XJL|go:"GO:0097066"(response to thyroid hormone)	refseq:NP_001091046.1|refseq:NP_001136.1|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0019732"(antifungal humoral response)|go:"GO:0019843"(rRNA binding)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030426"(growth cone)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0032311"(angiogenin-PRI complex)|go:"GO:0032431"(activation of phospholipase A2 activity)|go:"GO:0042277"(peptide binding)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042592"(homeostatic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045087"(innate immune response)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR001427(Pancreatic ribonuclease)|interpro:IPR023411|interpro:IPR023412|interpro:IPR036816|rcsb pdb:1A4Y|rcsb pdb:1ANG|go:"GO:0016078"(tRNA catabolic process)|go:"GO:0016477"(cell migration)|rcsb pdb:1AWZ|rcsb pdb:1B1E|rcsb pdb:1B1I|rcsb pdb:1B1J|rcsb pdb:1GV7|rcsb pdb:1H0D|rcsb pdb:1H52|rcsb pdb:1H53|rcsb pdb:1HBY|rcsb pdb:1K58|rcsb pdb:1K59|rcsb pdb:1K5A|rcsb pdb:1K5B|rcsb pdb:1UN3|rcsb pdb:1UN4|rcsb pdb:1UN5|rcsb pdb:2ANG|rcsb pdb:4AHD|rcsb pdb:4AHE|rcsb pdb:4AHF|rcsb pdb:4AHG|rcsb pdb:4AHH|rcsb pdb:4AHI|rcsb pdb:4AHJ|rcsb pdb:4AHK|rcsb pdb:4AHL|rcsb pdb:4AHM|rcsb pdb:4AHN|rcsb pdb:4AOH|rcsb pdb:4B36|rcsb pdb:5EOP|rcsb pdb:5EPZ|rcsb pdb:5EQO|rcsb pdb:5M9A|rcsb pdb:5M9C|rcsb pdb:5M9G|rcsb pdb:5M9J|rcsb pdb:5M9M|rcsb pdb:5M9P|rcsb pdb:5M9Q|rcsb pdb:5M9R|rcsb pdb:5M9S|rcsb pdb:5M9T|rcsb pdb:5M9V|reactome:R-HSA-418990|reactome:R-HSA-9708296|ensembl:ENSG00000214274(gene)|ensembl:ENST00000336811(transcript)|ensembl:ENST00000397990(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001878"(response to yeast)|go:"GO:0001890"(placenta development)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0003677"(DNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0004540"(ribonuclease activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005507"(copper ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006651"(diacylglycerol biosynthetic process)|go:"GO:0007154"(cell communication)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0008201"(heparin binding)|go:"GO:0009303"(rRNA transcription)|go:"GO:0009725"(response to hormone)|go:"GO:0015629"(actin cytoskeleton)	-	-	-	figure legend:4Bi|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-t47d-a18)|taxid:9606(ER- and PR-positive hormone-responsive clone of t47d)	-	2016/07/19	2016/08/24	rogid:jcB4Dt0LFv8YaBUnC2BSTCshveg9606	rogid:CSOTublnrV3DIGJfeyCfT14p8m89606	rigid:7O9WBu8P12ixsDwy0TJZNopjFOE	false	-	-	-	-	psi-mi:"MI:1200"(immunocytochemistry)	psi-mi:"MI:1200"(immunocytochemistry)
uniprotkb:P07355	uniprotkb:P60903	intact:EBI-352622|uniprotkb:Q567R4|uniprotkb:Q96DD5|intact:EBI-2211824|uniprotkb:Q6N0B3|uniprotkb:Q8TBV2|uniprotkb:Q9UDH8|ensembl:ENSP00000379342|ensembl:ENSP00000387545|ensembl:ENSP00000411352|ensembl:ENSP00000452858|ensembl:ENSP00000452895|ensembl:ENSP00000452981|ensembl:ENSP00000453694|ensembl:ENSP00000453859|ensembl:ENSP00000503447|ensembl:ENSP00000503757|ensembl:ENSP00000503855|ensembl:ENSP00000504035|ensembl:ENSP00000504164	intact:EBI-717048|uniprotkb:P08206|uniprotkb:Q5T1C5|uniprotkb:A8K4V8|ensembl:ENSP00000357799|ensembl:ENSP00000357801	psi-mi:anxa2_human(display_long)|uniprotkb:ANXA2(gene name)|psi-mi:ANXA2(display_short)|uniprotkb:ANX2(gene name synonym)|uniprotkb:ANX2L4(gene name synonym)|uniprotkb:CAL1H(gene name synonym)|uniprotkb:LPC2D(gene name synonym)|uniprotkb:Annexin-2(gene name synonym)|uniprotkb:Annexin II(gene name synonym)|uniprotkb:Lipocortin II(gene name synonym)|uniprotkb:Calpactin I heavy chain(gene name synonym)|uniprotkb:Chromobindin-8(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:Protein I(gene name synonym)|uniprotkb:Placental anticoagulant protein IV(gene name synonym)|uniprotkb:Calpactin-1 heavy chain(gene name synonym)	psi-mi:s10aa_human(display_long)|uniprotkb:S100 calcium-binding protein A10(gene name synonym)|uniprotkb:Calpactin-1 light chain(gene name synonym)|uniprotkb:Calpactin I light chain(gene name synonym)|uniprotkb:p10 protein(gene name synonym)|uniprotkb:p11(gene name synonym)|uniprotkb:Cellular ligand of annexin II(gene name synonym)|uniprotkb:S100A10(gene name)|psi-mi:S100A10(display_short)|uniprotkb:ANX2LG(gene name synonym)|uniprotkb:CAL1L(gene name synonym)|uniprotkb:CLP11(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Dutta et al. (2014)	imex:IM-25501|pubmed:24457100	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12513176|imex:IM-25501-17	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001002857.1|refseq:NP_001002858.1|refseq:NP_001129487.1|refseq:NP_004030.1|refseq:XP_016877579.1|refseq:XP_016877580.1|ensembl:ENSG00000182718(gene)|ensembl:ENST00000396024(transcript)|ensembl:ENST00000421017(transcript)|ensembl:ENST00000451270(transcript)|ensembl:ENST00000557906(transcript)|ensembl:ENST00000558558(transcript)|ensembl:ENST00000559818(transcript)|ensembl:ENST00000559956(transcript)|ensembl:ENST00000560468(transcript)|ensembl:ENST00000677968(transcript)|ensembl:ENST00000678061(transcript)|ensembl:ENST00000678450(transcript)|ensembl:ENST00000678870(transcript)|ensembl:ENST00000679109(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001726"(ruffle)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005938"(cell cortex)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0007589"(body fluid secretion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019834"(phospholipase A2 inhibitor activity)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031340"(positive regulation of vesicle fusion)|go:"GO:0031902"(late endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032804"(negative regulation of low-density lipoprotein particle receptor catabolic process)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035749"(myelin sheath adaxonal region)|go:"GO:0036035"(osteoclast development)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0042730"(fibrinolysis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0044090"(positive regulation of vacuole organization)|go:"GO:0044354"(macropinosome)|go:"GO:0044548"(S100 protein binding)|go:"GO:0044730"(bone sialoprotein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046790"(virion binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0005509"(calcium ion binding)|rcsb pdb:2HYU|rcsb pdb:2HYV|rcsb pdb:2HYW|rcsb pdb:4DRW|rcsb pdb:4FTG|rcsb pdb:4HRH|rcsb pdb:5LPU|rcsb pdb:5LPX|rcsb pdb:5LQ0|rcsb pdb:5LQ2|rcsb pdb:5N7D|rcsb pdb:5N7F|rcsb pdb:5N7G|rcsb pdb:6TWQ|rcsb pdb:6TWU|rcsb pdb:6TWX|rcsb pdb:6TWY|reactome:R-HSA-445355|reactome:R-HSA-6798695|reactome:R-HSA-75205|reactome:R-HSA-8950505|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:1905581"(positive regulation of low-density lipoprotein particle clearance)|go:"GO:1905597"(positive regulation of low-density lipoprotein particle receptor binding)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|go:"GO:1905602"(positive regulation of receptor-mediated endocytosis involved in cholesterol transport)|go:"GO:1990665"(AnxA2-p11 complex)|go:"GO:1990667"(PCSK9-AnxA2 complex)|interpro:IPR001464(Annexin)|interpro:IPR002389(Annexin, type II)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P07355|rcsb pdb:1W7B|rcsb pdb:1XJL|go:"GO:0097066"(response to thyroid hormone)	refseq:NP_002957.1|ensembl:ENSG00000197747(gene)|ensembl:ENST00000368809(transcript)|ensembl:ENST00000368811(transcript)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0005576"(extracellular region)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0042493"|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1990665"(AnxA2-p11 complex)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR028476|rcsb pdb:1A4P|rcsb pdb:1BT6|rcsb pdb:4DRW|rcsb pdb:4FTG|rcsb pdb:4HRE|rcsb pdb:4HRG|rcsb pdb:4HRH|reactome:R-HSA-75205	-	-	-	figure legend:4Bii|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-t47d-a18)|taxid:9606(ER- and PR-positive hormone-responsive clone of t47d)	-	2016/07/19	2016/08/24	rogid:jcB4Dt0LFv8YaBUnC2BSTCshveg9606	rogid:WlxwW4qaHp6tcyEAYvQ2ut9SyRA9606	rigid:eErnhjOKfUMyJ95HMLaTcX1A4M4	false	-	-	-	-	psi-mi:"MI:1200"(immunocytochemistry)	psi-mi:"MI:1200"(immunocytochemistry)
uniprotkb:P03950	uniprotkb:P60903	intact:EBI-525291|uniprotkb:Q8WXE7|uniprotkb:Q05CV1|uniprotkb:Q53X86|uniprotkb:Q6P5T2|ensembl:ENSP00000336762|ensembl:ENSP00000381077	intact:EBI-717048|uniprotkb:P08206|uniprotkb:Q5T1C5|uniprotkb:A8K4V8|ensembl:ENSP00000357799|ensembl:ENSP00000357801	psi-mi:angi_human(display_long)|uniprotkb:Ribonuclease 5(gene name synonym)|uniprotkb:ANG(gene name)|psi-mi:ANG(display_short)|uniprotkb:RNASE5(gene name synonym)	psi-mi:s10aa_human(display_long)|uniprotkb:S100 calcium-binding protein A10(gene name synonym)|uniprotkb:Calpactin-1 light chain(gene name synonym)|uniprotkb:Calpactin I light chain(gene name synonym)|uniprotkb:p10 protein(gene name synonym)|uniprotkb:p11(gene name synonym)|uniprotkb:Cellular ligand of annexin II(gene name synonym)|uniprotkb:S100A10(gene name)|psi-mi:S100A10(display_short)|uniprotkb:ANX2LG(gene name synonym)|uniprotkb:CAL1L(gene name synonym)|uniprotkb:CLP11(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Dutta et al. (2014)	imex:IM-25501|pubmed:24457100	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12513181|imex:IM-25501-19	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001091046.1|refseq:NP_001136.1|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0019732"(antifungal humoral response)|go:"GO:0019843"(rRNA binding)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030426"(growth cone)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0032311"(angiogenin-PRI complex)|go:"GO:0032431"(activation of phospholipase A2 activity)|go:"GO:0042277"(peptide binding)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042592"(homeostatic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045087"(innate immune response)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR001427(Pancreatic ribonuclease)|interpro:IPR023411|interpro:IPR023412|interpro:IPR036816|rcsb pdb:1A4Y|rcsb pdb:1ANG|go:"GO:0016078"(tRNA catabolic process)|go:"GO:0016477"(cell migration)|rcsb pdb:1AWZ|rcsb pdb:1B1E|rcsb pdb:1B1I|rcsb pdb:1B1J|rcsb pdb:1GV7|rcsb pdb:1H0D|rcsb pdb:1H52|rcsb pdb:1H53|rcsb pdb:1HBY|rcsb pdb:1K58|rcsb pdb:1K59|rcsb pdb:1K5A|rcsb pdb:1K5B|rcsb pdb:1UN3|rcsb pdb:1UN4|rcsb pdb:1UN5|rcsb pdb:2ANG|rcsb pdb:4AHD|rcsb pdb:4AHE|rcsb pdb:4AHF|rcsb pdb:4AHG|rcsb pdb:4AHH|rcsb pdb:4AHI|rcsb pdb:4AHJ|rcsb pdb:4AHK|rcsb pdb:4AHL|rcsb pdb:4AHM|rcsb pdb:4AHN|rcsb pdb:4AOH|rcsb pdb:4B36|rcsb pdb:5EOP|rcsb pdb:5EPZ|rcsb pdb:5EQO|rcsb pdb:5M9A|rcsb pdb:5M9C|rcsb pdb:5M9G|rcsb pdb:5M9J|rcsb pdb:5M9M|rcsb pdb:5M9P|rcsb pdb:5M9Q|rcsb pdb:5M9R|rcsb pdb:5M9S|rcsb pdb:5M9T|rcsb pdb:5M9V|reactome:R-HSA-418990|reactome:R-HSA-9708296|ensembl:ENSG00000214274(gene)|ensembl:ENST00000336811(transcript)|ensembl:ENST00000397990(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001878"(response to yeast)|go:"GO:0001890"(placenta development)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0003677"(DNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0004540"(ribonuclease activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005507"(copper ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006651"(diacylglycerol biosynthetic process)|go:"GO:0007154"(cell communication)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0008201"(heparin binding)|go:"GO:0009303"(rRNA transcription)|go:"GO:0009725"(response to hormone)|go:"GO:0015629"(actin cytoskeleton)	refseq:NP_002957.1|ensembl:ENSG00000197747(gene)|ensembl:ENST00000368809(transcript)|ensembl:ENST00000368811(transcript)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0005576"(extracellular region)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0042493"|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1990665"(AnxA2-p11 complex)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR028476|rcsb pdb:1A4P|rcsb pdb:1BT6|rcsb pdb:4DRW|rcsb pdb:4FTG|rcsb pdb:4HRE|rcsb pdb:4HRG|rcsb pdb:4HRH|reactome:R-HSA-75205	-	-	-	figure legend:4C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-t47d-a18)|taxid:9606(ER- and PR-positive hormone-responsive clone of t47d)	-	2016/07/19	2016/08/24	rogid:CSOTublnrV3DIGJfeyCfT14p8m89606	rogid:WlxwW4qaHp6tcyEAYvQ2ut9SyRA9606	rigid:Hk3H0FRfE8uCLp+oPlOpgxBFKb4	false	-	-	-	-	psi-mi:"MI:1200"(immunocytochemistry)	psi-mi:"MI:1200"(immunocytochemistry)
uniprotkb:P03950	uniprotkb:Q03405	intact:EBI-525291|uniprotkb:Q8WXE7|uniprotkb:Q05CV1|uniprotkb:Q53X86|uniprotkb:Q6P5T2|ensembl:ENSP00000336762|ensembl:ENSP00000381077	intact:EBI-716505|uniprotkb:Q12876|uniprotkb:Q15845|uniprotkb:Q16887|uniprotkb:Q6IB52|uniprotkb:Q9BWT0|uniprotkb:Q9NYC8|uniprotkb:Q9UD69|uniprotkb:Q9UEA6|uniprotkb:Q9UM92|uniprotkb:Q9UMV0|uniprotkb:A8K409|ensembl:ENSP00000339328	psi-mi:angi_human(display_long)|uniprotkb:Ribonuclease 5(gene name synonym)|uniprotkb:ANG(gene name)|psi-mi:ANG(display_short)|uniprotkb:RNASE5(gene name synonym)	psi-mi:upar_human(display_long)|uniprotkb:Monocyte activation antigen Mo3(gene name synonym)|uniprotkb:PLAUR(gene name)|psi-mi:PLAUR(display_short)|uniprotkb:MO3(gene name synonym)|uniprotkb:UPAR(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Dutta et al. (2014)	imex:IM-25501|pubmed:24457100	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12513181|imex:IM-25501-19	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001091046.1|refseq:NP_001136.1|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0019732"(antifungal humoral response)|go:"GO:0019843"(rRNA binding)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030426"(growth cone)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0032311"(angiogenin-PRI complex)|go:"GO:0032431"(activation of phospholipase A2 activity)|go:"GO:0042277"(peptide binding)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042592"(homeostatic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045087"(innate immune response)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR001427(Pancreatic ribonuclease)|interpro:IPR023411|interpro:IPR023412|interpro:IPR036816|rcsb pdb:1A4Y|rcsb pdb:1ANG|go:"GO:0016078"(tRNA catabolic process)|go:"GO:0016477"(cell migration)|rcsb pdb:1AWZ|rcsb pdb:1B1E|rcsb pdb:1B1I|rcsb pdb:1B1J|rcsb pdb:1GV7|rcsb pdb:1H0D|rcsb pdb:1H52|rcsb pdb:1H53|rcsb pdb:1HBY|rcsb pdb:1K58|rcsb pdb:1K59|rcsb pdb:1K5A|rcsb pdb:1K5B|rcsb pdb:1UN3|rcsb pdb:1UN4|rcsb pdb:1UN5|rcsb pdb:2ANG|rcsb pdb:4AHD|rcsb pdb:4AHE|rcsb pdb:4AHF|rcsb pdb:4AHG|rcsb pdb:4AHH|rcsb pdb:4AHI|rcsb pdb:4AHJ|rcsb pdb:4AHK|rcsb pdb:4AHL|rcsb pdb:4AHM|rcsb pdb:4AHN|rcsb pdb:4AOH|rcsb pdb:4B36|rcsb pdb:5EOP|rcsb pdb:5EPZ|rcsb pdb:5EQO|rcsb pdb:5M9A|rcsb pdb:5M9C|rcsb pdb:5M9G|rcsb pdb:5M9J|rcsb pdb:5M9M|rcsb pdb:5M9P|rcsb pdb:5M9Q|rcsb pdb:5M9R|rcsb pdb:5M9S|rcsb pdb:5M9T|rcsb pdb:5M9V|reactome:R-HSA-418990|reactome:R-HSA-9708296|ensembl:ENSG00000214274(gene)|ensembl:ENST00000336811(transcript)|ensembl:ENST00000397990(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001878"(response to yeast)|go:"GO:0001890"(placenta development)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0003677"(DNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0004540"(ribonuclease activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005507"(copper ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006651"(diacylglycerol biosynthetic process)|go:"GO:0007154"(cell communication)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0008201"(heparin binding)|go:"GO:0009303"(rRNA transcription)|go:"GO:0009725"(response to hormone)|go:"GO:0015629"(actin cytoskeleton)	refseq:NP_001005376.1|refseq:NP_001005377.1|refseq:NP_002650.1|reactome:R-HSA-162791|reactome:R-HSA-6798695|reactome:R-HSA-75205|rcsb pdb:4QTI|ensembl:ENSG00000011422(gene)|ensembl:ENST00000340093(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006935"(chemotaxis)|go:"GO:0007165"(signal transduction)|go:"GO:0007596"(blood coagulation)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030162"(regulation of proteolysis)|go:"GO:0030377"(urokinase plasminogen activator receptor activity)|go:"GO:0034112"(positive regulation of homotypic cell-cell adhesion)|go:"GO:0035579"(specific granule membrane)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042995"(cell projection)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|go:"GO:0031225"(anchored component of membrane)|go:"GO:2001268"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|interpro:IPR018363|interpro:IPR033084|rcsb pdb:1YWH|rcsb pdb:2FD6|rcsb pdb:2I9B|rcsb pdb:3BT1|rcsb pdb:3BT2|rcsb pdb:3U73|rcsb pdb:3U74|rcsb pdb:4K24|refseq:NP_001287966.1|dip:DIP-137N	-	-	-	figure legend:4C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-t47d-a18)|taxid:9606(ER- and PR-positive hormone-responsive clone of t47d)	-	2016/07/19	2016/08/24	rogid:CSOTublnrV3DIGJfeyCfT14p8m89606	rogid:faxxSUpKpPAaAlPpUpvg2NG4DOA9606	rigid:Hk3H0FRfE8uCLp+oPlOpgxBFKb4	false	-	-	-	-	psi-mi:"MI:1200"(immunocytochemistry)	psi-mi:"MI:1200"(immunocytochemistry)
uniprotkb:Q03405	uniprotkb:P03950	intact:EBI-716505|uniprotkb:Q12876|uniprotkb:Q15845|uniprotkb:Q16887|uniprotkb:Q6IB52|uniprotkb:Q9BWT0|uniprotkb:Q9NYC8|uniprotkb:Q9UD69|uniprotkb:Q9UEA6|uniprotkb:Q9UM92|uniprotkb:Q9UMV0|uniprotkb:A8K409|ensembl:ENSP00000339328	intact:EBI-525291|uniprotkb:Q8WXE7|uniprotkb:Q05CV1|uniprotkb:Q53X86|uniprotkb:Q6P5T2|ensembl:ENSP00000336762|ensembl:ENSP00000381077	psi-mi:upar_human(display_long)|uniprotkb:Monocyte activation antigen Mo3(gene name synonym)|uniprotkb:PLAUR(gene name)|psi-mi:PLAUR(display_short)|uniprotkb:MO3(gene name synonym)|uniprotkb:UPAR(gene name synonym)	psi-mi:angi_human(display_long)|uniprotkb:Ribonuclease 5(gene name synonym)|uniprotkb:ANG(gene name)|psi-mi:ANG(display_short)|uniprotkb:RNASE5(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Dutta et al. (2014)	imex:IM-25501|pubmed:24457100	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12513191|imex:IM-25501-33	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001005376.1|refseq:NP_001005377.1|refseq:NP_002650.1|reactome:R-HSA-162791|reactome:R-HSA-6798695|reactome:R-HSA-75205|rcsb pdb:4QTI|ensembl:ENSG00000011422(gene)|ensembl:ENST00000340093(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006935"(chemotaxis)|go:"GO:0007165"(signal transduction)|go:"GO:0007596"(blood coagulation)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030162"(regulation of proteolysis)|go:"GO:0030377"(urokinase plasminogen activator receptor activity)|go:"GO:0034112"(positive regulation of homotypic cell-cell adhesion)|go:"GO:0035579"(specific granule membrane)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042995"(cell projection)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|go:"GO:0031225"(anchored component of membrane)|go:"GO:2001268"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|interpro:IPR018363|interpro:IPR033084|rcsb pdb:1YWH|rcsb pdb:2FD6|rcsb pdb:2I9B|rcsb pdb:3BT1|rcsb pdb:3BT2|rcsb pdb:3U73|rcsb pdb:3U74|rcsb pdb:4K24|refseq:NP_001287966.1|dip:DIP-137N	refseq:NP_001091046.1|refseq:NP_001136.1|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0019732"(antifungal humoral response)|go:"GO:0019843"(rRNA binding)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030426"(growth cone)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0032311"(angiogenin-PRI complex)|go:"GO:0032431"(activation of phospholipase A2 activity)|go:"GO:0042277"(peptide binding)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042592"(homeostatic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045087"(innate immune response)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR001427(Pancreatic ribonuclease)|interpro:IPR023411|interpro:IPR023412|interpro:IPR036816|rcsb pdb:1A4Y|rcsb pdb:1ANG|go:"GO:0016078"(tRNA catabolic process)|go:"GO:0016477"(cell migration)|rcsb pdb:1AWZ|rcsb pdb:1B1E|rcsb pdb:1B1I|rcsb pdb:1B1J|rcsb pdb:1GV7|rcsb pdb:1H0D|rcsb pdb:1H52|rcsb pdb:1H53|rcsb pdb:1HBY|rcsb pdb:1K58|rcsb pdb:1K59|rcsb pdb:1K5A|rcsb pdb:1K5B|rcsb pdb:1UN3|rcsb pdb:1UN4|rcsb pdb:1UN5|rcsb pdb:2ANG|rcsb pdb:4AHD|rcsb pdb:4AHE|rcsb pdb:4AHF|rcsb pdb:4AHG|rcsb pdb:4AHH|rcsb pdb:4AHI|rcsb pdb:4AHJ|rcsb pdb:4AHK|rcsb pdb:4AHL|rcsb pdb:4AHM|rcsb pdb:4AHN|rcsb pdb:4AOH|rcsb pdb:4B36|rcsb pdb:5EOP|rcsb pdb:5EPZ|rcsb pdb:5EQO|rcsb pdb:5M9A|rcsb pdb:5M9C|rcsb pdb:5M9G|rcsb pdb:5M9J|rcsb pdb:5M9M|rcsb pdb:5M9P|rcsb pdb:5M9Q|rcsb pdb:5M9R|rcsb pdb:5M9S|rcsb pdb:5M9T|rcsb pdb:5M9V|reactome:R-HSA-418990|reactome:R-HSA-9708296|ensembl:ENSG00000214274(gene)|ensembl:ENST00000336811(transcript)|ensembl:ENST00000397990(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001878"(response to yeast)|go:"GO:0001890"(placenta development)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0003677"(DNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0004540"(ribonuclease activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005507"(copper ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006651"(diacylglycerol biosynthetic process)|go:"GO:0007154"(cell communication)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0008201"(heparin binding)|go:"GO:0009303"(rRNA transcription)|go:"GO:0009725"(response to hormone)|go:"GO:0015629"(actin cytoskeleton)	-	-	-	figure legend:4Ci|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-t47d-a18)|taxid:9606(ER- and PR-positive hormone-responsive clone of t47d)	-	2016/07/19	2016/08/24	rogid:faxxSUpKpPAaAlPpUpvg2NG4DOA9606	rogid:CSOTublnrV3DIGJfeyCfT14p8m89606	rigid:MoQU+5+dO8o7aWpoudCs4v1TnPQ	false	-	-	-	-	psi-mi:"MI:1200"(immunocytochemistry)	psi-mi:"MI:1200"(immunocytochemistry)
uniprotkb:Q03405	uniprotkb:P60903	intact:EBI-716505|uniprotkb:Q12876|uniprotkb:Q15845|uniprotkb:Q16887|uniprotkb:Q6IB52|uniprotkb:Q9BWT0|uniprotkb:Q9NYC8|uniprotkb:Q9UD69|uniprotkb:Q9UEA6|uniprotkb:Q9UM92|uniprotkb:Q9UMV0|uniprotkb:A8K409|ensembl:ENSP00000339328	intact:EBI-717048|uniprotkb:P08206|uniprotkb:Q5T1C5|uniprotkb:A8K4V8|ensembl:ENSP00000357799|ensembl:ENSP00000357801	psi-mi:upar_human(display_long)|uniprotkb:Monocyte activation antigen Mo3(gene name synonym)|uniprotkb:PLAUR(gene name)|psi-mi:PLAUR(display_short)|uniprotkb:MO3(gene name synonym)|uniprotkb:UPAR(gene name synonym)	psi-mi:s10aa_human(display_long)|uniprotkb:S100 calcium-binding protein A10(gene name synonym)|uniprotkb:Calpactin-1 light chain(gene name synonym)|uniprotkb:Calpactin I light chain(gene name synonym)|uniprotkb:p10 protein(gene name synonym)|uniprotkb:p11(gene name synonym)|uniprotkb:Cellular ligand of annexin II(gene name synonym)|uniprotkb:S100A10(gene name)|psi-mi:S100A10(display_short)|uniprotkb:ANX2LG(gene name synonym)|uniprotkb:CAL1L(gene name synonym)|uniprotkb:CLP11(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Dutta et al. (2014)	imex:IM-25501|pubmed:24457100	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12513196|imex:IM-25501-35	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001005376.1|refseq:NP_001005377.1|refseq:NP_002650.1|reactome:R-HSA-162791|reactome:R-HSA-6798695|reactome:R-HSA-75205|rcsb pdb:4QTI|ensembl:ENSG00000011422(gene)|ensembl:ENST00000340093(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006935"(chemotaxis)|go:"GO:0007165"(signal transduction)|go:"GO:0007596"(blood coagulation)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030162"(regulation of proteolysis)|go:"GO:0030377"(urokinase plasminogen activator receptor activity)|go:"GO:0034112"(positive regulation of homotypic cell-cell adhesion)|go:"GO:0035579"(specific granule membrane)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042995"(cell projection)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|go:"GO:0031225"(anchored component of membrane)|go:"GO:2001268"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|interpro:IPR018363|interpro:IPR033084|rcsb pdb:1YWH|rcsb pdb:2FD6|rcsb pdb:2I9B|rcsb pdb:3BT1|rcsb pdb:3BT2|rcsb pdb:3U73|rcsb pdb:3U74|rcsb pdb:4K24|refseq:NP_001287966.1|dip:DIP-137N	refseq:NP_002957.1|ensembl:ENSG00000197747(gene)|ensembl:ENST00000368809(transcript)|ensembl:ENST00000368811(transcript)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0005576"(extracellular region)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0042493"|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1990665"(AnxA2-p11 complex)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR028476|rcsb pdb:1A4P|rcsb pdb:1BT6|rcsb pdb:4DRW|rcsb pdb:4FTG|rcsb pdb:4HRE|rcsb pdb:4HRG|rcsb pdb:4HRH|reactome:R-HSA-75205	-	-	-	figure legend:4Cii|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-t47d-a18)|taxid:9606(ER- and PR-positive hormone-responsive clone of t47d)	-	2016/07/19	2016/08/24	rogid:faxxSUpKpPAaAlPpUpvg2NG4DOA9606	rogid:WlxwW4qaHp6tcyEAYvQ2ut9SyRA9606	rigid:UhWcLW8gaRSi/GIQsrTAGyq4nnY	false	-	-	-	-	psi-mi:"MI:1200"(immunocytochemistry)	psi-mi:"MI:1200"(immunocytochemistry)