#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:O76071	uniprotkb:Q8WXG1	intact:EBI-725145|uniprotkb:A0MNN9|uniprotkb:Q53FM5|ensembl:ENSP00000418287	intact:EBI-12736320|ensembl:ENSP00000371471|ensembl:ENSP00000506390|uniprotkb:Q8WVI4	psi-mi:ciao1_human(display_long)|uniprotkb:WD repeat-containing protein 39(gene name synonym)|uniprotkb:CIAO1(gene name)|psi-mi:CIAO1(display_short)|uniprotkb:WDR39(gene name synonym)|uniprotkb:CIA1(gene name synonym)	psi-mi:rsad2_human(display_long)|uniprotkb:RSAD2(gene name)|psi-mi:RSAD2(display_short)|uniprotkb:CIG5(gene name synonym)|uniprotkb:Cytomegalovirus-induced gene 5 protein(gene name synonym)|uniprotkb:Viperin(gene name synonym)|uniprotkb:Virus inhibitory protein, endoplasmic reticulum-associated, interferon-inducible(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Upadhyay et al. (2014)	pubmed:24245804|imex:IM-25633	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12736318|imex:IM-25633-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004795.1|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR028608|interpro:IPR036322|mint:O76071|rcsb pdb:3FM0|reactome:R-HSA-2564830|ensembl:ENSG00000144021(gene)|ensembl:ENST00000488633(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0071817"(MMXD complex)|go:"GO:0097361"(CIA complex)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)	ensembl:ENSG00000134321(gene)|ensembl:ENST00000382040(transcript)|ensembl:ENST00000680607(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005811"(lipid droplet)|go:"GO:0009615"(response to virus)|go:"GO:0016829"(lyase activity)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034165"(positive regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035710"(CD4-positive, alpha-beta T cell activation)|go:"GO:0043367"(CD4-positive, alpha-beta T cell differentiation)|go:"GO:0043621"(protein self-association)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0050709"(negative regulation of protein secretion)|go:"GO:0050778"(positive regulation of immune response)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0051607"(defense response to virus)|go:"GO:2000553"(positive regulation of T-helper 2 cell cytokine production)|interpro:IPR006638(Elongator protein 3/MiaB/NifB)|interpro:IPR007197(Radical SAM)|interpro:IPR013785(Aldolase-type TIM barrel)|reactome:R-HSA-909733|go:"GO:0005741"(mitochondrial outer membrane)|refseq:NP_542388.2|refseq:XP_011508716.1	-	-	-	figure legend:6A, 7A|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2016/12/19	2017/01/10	rogid:Lm4qlRM/4M+yz9miSayiAnBh5Dk9606	rogid:QnLTJeMdPIWXBGvLNOj12/BzJWw9606	rigid:VjRmXju8ZKyEgmSGMxmjEg2nPCE	false	-	mutation disrupting interaction strength:361-361|mutation disrupting interaction strength:361-361|flag tag:n-n|mutation with no effect:83-83,87-87,90-90|sufficient binding region:51-361	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O76071	uniprotkb:Q8WXG1	intact:EBI-725145|uniprotkb:A0MNN9|uniprotkb:Q53FM5|ensembl:ENSP00000418287	intact:EBI-12736320|ensembl:ENSP00000371471|ensembl:ENSP00000506390|uniprotkb:Q8WVI4	psi-mi:ciao1_human(display_long)|uniprotkb:WD repeat-containing protein 39(gene name synonym)|uniprotkb:CIAO1(gene name)|psi-mi:CIAO1(display_short)|uniprotkb:WDR39(gene name synonym)|uniprotkb:CIA1(gene name synonym)	psi-mi:rsad2_human(display_long)|uniprotkb:RSAD2(gene name)|psi-mi:RSAD2(display_short)|uniprotkb:CIG5(gene name synonym)|uniprotkb:Cytomegalovirus-induced gene 5 protein(gene name synonym)|uniprotkb:Viperin(gene name synonym)|uniprotkb:Virus inhibitory protein, endoplasmic reticulum-associated, interferon-inducible(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Upadhyay et al. (2014)	pubmed:24245804|imex:IM-25633	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12736362|imex:IM-25633-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004795.1|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR028608|interpro:IPR036322|mint:O76071|rcsb pdb:3FM0|reactome:R-HSA-2564830|ensembl:ENSG00000144021(gene)|ensembl:ENST00000488633(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0071817"(MMXD complex)|go:"GO:0097361"(CIA complex)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)	ensembl:ENSG00000134321(gene)|ensembl:ENST00000382040(transcript)|ensembl:ENST00000680607(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005811"(lipid droplet)|go:"GO:0009615"(response to virus)|go:"GO:0016829"(lyase activity)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034165"(positive regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035710"(CD4-positive, alpha-beta T cell activation)|go:"GO:0043367"(CD4-positive, alpha-beta T cell differentiation)|go:"GO:0043621"(protein self-association)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0050709"(negative regulation of protein secretion)|go:"GO:0050778"(positive regulation of immune response)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0051607"(defense response to virus)|go:"GO:2000553"(positive regulation of T-helper 2 cell cytokine production)|interpro:IPR006638(Elongator protein 3/MiaB/NifB)|interpro:IPR007197(Radical SAM)|interpro:IPR013785(Aldolase-type TIM barrel)|reactome:R-HSA-909733|go:"GO:0005741"(mitochondrial outer membrane)|refseq:NP_542388.2|refseq:XP_011508716.1	-	-	-	figure legend:6B|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2016/12/19	2017/01/10	rogid:Lm4qlRM/4M+yz9miSayiAnBh5Dk9606	rogid:QnLTJeMdPIWXBGvLNOj12/BzJWw9606	rigid:VjRmXju8ZKyEgmSGMxmjEg2nPCE	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
chebi:"CHEBI:18248"	uniprotkb:Q8WXG1	intact:EBI-1252632	intact:EBI-12736320|ensembl:ENSP00000371471|ensembl:ENSP00000506390|uniprotkb:Q8WVI4	psi-mi:iron(display_short)|psi-mi:"CHEBI:18248"(display_long)	psi-mi:rsad2_human(display_long)|uniprotkb:RSAD2(gene name)|psi-mi:RSAD2(display_short)|uniprotkb:CIG5(gene name synonym)|uniprotkb:Cytomegalovirus-induced gene 5 protein(gene name synonym)|uniprotkb:Viperin(gene name synonym)|uniprotkb:Virus inhibitory protein, endoplasmic reticulum-associated, interferon-inducible(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Upadhyay et al. (2014)	pubmed:24245804|imex:IM-25633	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-12736403|imex:IM-25633-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSG00000134321(gene)|ensembl:ENST00000382040(transcript)|ensembl:ENST00000680607(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005811"(lipid droplet)|go:"GO:0009615"(response to virus)|go:"GO:0016829"(lyase activity)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034165"(positive regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035710"(CD4-positive, alpha-beta T cell activation)|go:"GO:0043367"(CD4-positive, alpha-beta T cell differentiation)|go:"GO:0043621"(protein self-association)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0050709"(negative regulation of protein secretion)|go:"GO:0050778"(positive regulation of immune response)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0051607"(defense response to virus)|go:"GO:2000553"(positive regulation of T-helper 2 cell cytokine production)|interpro:IPR006638(Elongator protein 3/MiaB/NifB)|interpro:IPR007197(Radical SAM)|interpro:IPR013785(Aldolase-type TIM barrel)|reactome:R-HSA-909733|go:"GO:0005741"(mitochondrial outer membrane)|refseq:NP_542388.2|refseq:XP_011508716.1	-	-	-	figure legend:7D, 8D|antagonist:CIAO1  depletion|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2016/12/19	2017/01/10	-	rogid:QnLTJeMdPIWXBGvLNOj12/BzJWw9606	-	false	radiolabel:?-?	mutation disrupting interaction strength:361-361|flag tag:n-n|mutation disrupting interaction strength:83-83,87-87,90-90|necessary binding region:341-361	-	-	psi-mi:"MI:0866"(tag visualisation)	psi-mi:"MI:0866"(tag visualisation)