#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P49171	uniprotkb:Q5U8X5	intact:EBI-12576732|ensembl:ENSSSCP00070050954|uniprotkb:A1XQV1	intact:EBI-12557210	psi-mi:rs26_pig(display_long)|uniprotkb:RPS26(gene name)|psi-mi:RPS26(display_short)	psi-mi:q5u8x5_9flav(display_long)|uniprotkb:Capsid protein C(gene name synonym)|uniprotkb:Cysteine protease NS2(gene name synonym)|uniprotkb:"E(rns) glycoprotein"(gene name synonym)|uniprotkb:Envelope glycoprotein E1(gene name synonym)|uniprotkb:Envelope glycoprotein E2(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:N-terminal protease(gene name synonym)|uniprotkb:NS5B(gene name synonym)|uniprotkb:Non-structural protein 2(gene name synonym)|uniprotkb:Non-structural protein 2-3(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Non-structural protein 5A(gene name synonym)|uniprotkb:RNA-directed RNA polymerase(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:gp33(gene name synonym)|uniprotkb:gp44/48(gene name synonym)|uniprotkb:gp55(gene name synonym)|uniprotkb:Viroporin p7(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	He et al. (2014)	pubmed:24184320|imex:IM-25910	taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)")	taxid:11096(classical swine fever virus)|taxid:11096(Classical swine fever virus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-12576458|imex:IM-25910-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSSSCG00070029753(gene)|ensembl:ENSSSCT00070059806(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0098556"(cytoplasmic side of rough endoplasmic reticulum membrane)|interpro:IPR000892(Ribosomal protein S26e)|interpro:IPR038551|rcsb pdb:3J7P|rcsb pdb:3J7R|refseq:NP_001090950.1	go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033897"(ribonuclease T2 activity)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044228"(host cell surface)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0070008"(serine-type exopeptidase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR042311|interpro:IPR042309|interpro:IPR042310|interpro:IPR021824|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR022120|interpro:IPR030399|interpro:IPR027417|interpro:IPR008751(Peptidase C53, pestivirus Npro)|interpro:IPR032521|interpro:IPR000280(Peptidase S31, pestivurus polyprotein NS3/p80)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR033130|interpro:IPR042542|interpro:IPR036430|rcsb pdb:5WX1|rcsb pdb:5YF5|rcsb pdb:5YF6|rcsb pdb:5YF7|rcsb pdb:5YF8|rcsb pdb:6AE4|rcsb pdb:6AE5|rcsb pdb:6AE6|rcsb pdb:6AE7|interpro:IPR043502|interpro:IPR043128	-	-	-	figure legend:table s2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2016/08/24	2016/11/30	rogid:bo2ruYMNjjLCMo/kwAWzmlJrrjU9823	rogid:ztG+uovVXdRDsNER3V/Xz69PFsA11096	rigid:W2VdUjKsWtiw3RJM4LPbqLK2+ag	false	-	binding-associated region:691..691-1054..1054	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q6QAQ1	uniprotkb:Q5U8X5	intact:EBI-12513903|ensembl:ENSSSCP00000035521|ensembl:ENSSSCP00005020052|ensembl:ENSSSCP00005020098|ensembl:ENSSSCP00030001789|ensembl:ENSSSCP00035020643|ensembl:ENSSSCP00040028298|ensembl:ENSSSCP00045032503|ensembl:ENSSSCP00050037989|ensembl:ENSSSCP00055019840|ensembl:ENSSSCP00055019871|ensembl:ENSSSCP00055019955|ensembl:ENSSSCP00060010890|ensembl:ENSSSCP00065022539|ensembl:ENSSSCP00065022540|ensembl:ENSSSCP00065022543|ensembl:ENSSSCP00070018415|ensembl:ENSSSCP00070018418	intact:EBI-12557210	psi-mi:actb_pig(display_long)|uniprotkb:Beta-actin(gene name synonym)|uniprotkb:ACTB(gene name)|psi-mi:ACTB(display_short)	psi-mi:q5u8x5_9flav(display_long)|uniprotkb:Capsid protein C(gene name synonym)|uniprotkb:Cysteine protease NS2(gene name synonym)|uniprotkb:"E(rns) glycoprotein"(gene name synonym)|uniprotkb:Envelope glycoprotein E1(gene name synonym)|uniprotkb:Envelope glycoprotein E2(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:N-terminal protease(gene name synonym)|uniprotkb:NS5B(gene name synonym)|uniprotkb:Non-structural protein 2(gene name synonym)|uniprotkb:Non-structural protein 2-3(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Non-structural protein 5A(gene name synonym)|uniprotkb:RNA-directed RNA polymerase(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:gp33(gene name synonym)|uniprotkb:gp44/48(gene name synonym)|uniprotkb:gp55(gene name synonym)|uniprotkb:Viroporin p7(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	He et al. (2014)	pubmed:24184320|imex:IM-25910	taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)")	taxid:11096(classical swine fever virus)|taxid:11096(Classical swine fever virus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-12654285|imex:IM-25910-45	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSSSCG00000007585(gene)|ensembl:ENSSSCG00005020690(gene)|ensembl:ENSSSCG00030003451(gene)|ensembl:ENSSSCG00035038792(gene)|ensembl:ENSSSCG00040049462(gene)|ensembl:ENSSSCG00045027458(gene)|ensembl:ENSSSCG00050065025(gene)|ensembl:ENSSSCG00055012597(gene)|ensembl:ENSSSCG00060019124(gene)|ensembl:ENSSSCG00065037921(gene)|ensembl:ENSSSCG00070011353(gene)|ensembl:ENSSSCT00000042531(transcript)|ensembl:ENSSSCT00005032891(transcript)|ensembl:ENSSSCT00005032974(transcript)|ensembl:ENSSSCT00030004519(transcript)|ensembl:ENSSSCT00035051497(transcript)|ensembl:ENSSSCT00040066726(transcript)|ensembl:ENSSSCT00045046823(transcript)|ensembl:ENSSSCT00050088575(transcript)|ensembl:ENSSSCT00055024985(transcript)|ensembl:ENSSSCT00055025023(transcript)|ensembl:ENSSSCT00055025117(transcript)|ensembl:ENSSSCT00060025751(transcript)|ensembl:ENSSSCT00065051863(transcript)|ensembl:ENSSSCT00065051865(transcript)|ensembl:ENSSSCT00065051872(transcript)|ensembl:ENSSSCT00070022245(transcript)|ensembl:ENSSSCT00070022248(transcript)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007409"(axonogenesis)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022898"(regulation of transmembrane transporter activity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030424"(axon)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030957"(Tat protein binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045176"(apical protein localization)|go:"GO:0045202"(synapse)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048870"(cell motility)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051621"(regulation of norepinephrine uptake)|go:"GO:0070160"(tight junction)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0072749"(cellular response to cytochalasin B)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0150111"(regulation of transepithelial transport)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|rcsb pdb:5ADX|rcsb pdb:5AFU|rcsb pdb:6F1T|rcsb pdb:6F38|rcsb pdb:6F3A|rcsb pdb:6ZNL|rcsb pdb:6ZNM|rcsb pdb:6ZNN|rcsb pdb:6ZNO|rcsb pdb:6ZO4|reactome:R-SSC-190873|reactome:R-SSC-196025|reactome:R-SSC-2029482|reactome:R-SSC-4420097|reactome:R-SSC-446353|reactome:R-SSC-5250924|reactome:R-SSC-5626467|reactome:R-SSC-5663213|reactome:R-SSC-5663220|reactome:R-SSC-5674135|reactome:R-SSC-5689603|reactome:R-SSC-8856828|reactome:R-SSC-9035034|refseq:XP_003124328.1	go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033897"(ribonuclease T2 activity)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044228"(host cell surface)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0070008"(serine-type exopeptidase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR042311|interpro:IPR042309|interpro:IPR042310|interpro:IPR021824|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR022120|interpro:IPR030399|interpro:IPR027417|interpro:IPR008751(Peptidase C53, pestivirus Npro)|interpro:IPR032521|interpro:IPR000280(Peptidase S31, pestivurus polyprotein NS3/p80)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR033130|interpro:IPR042542|interpro:IPR036430|rcsb pdb:5WX1|rcsb pdb:5YF5|rcsb pdb:5YF6|rcsb pdb:5YF7|rcsb pdb:5YF8|rcsb pdb:6AE4|rcsb pdb:6AE5|rcsb pdb:6AE6|rcsb pdb:6AE7|interpro:IPR043502|interpro:IPR043128	-	-	-	figure legend:table s2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2016/08/24	2016/11/30	rogid:Hoge1B8Pn56kvbNTpkSLsQuHwRc9823	rogid:ztG+uovVXdRDsNER3V/Xz69PFsA11096	rigid:jizNxhYKdE2czkFcmYp1LLncMFA	false	-	binding-associated region:691..691-1054..1054	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:B6VAQ2	uniprotkb:Q5U8X5	intact:EBI-12576746	intact:EBI-12557210	psi-mi:b6vaq2_pig(display_long)|uniprotkb:PSMA6(gene name)|psi-mi:PSMA6(display_short)	psi-mi:q5u8x5_9flav(display_long)|uniprotkb:Capsid protein C(gene name synonym)|uniprotkb:Cysteine protease NS2(gene name synonym)|uniprotkb:"E(rns) glycoprotein"(gene name synonym)|uniprotkb:Envelope glycoprotein E1(gene name synonym)|uniprotkb:Envelope glycoprotein E2(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:N-terminal protease(gene name synonym)|uniprotkb:NS5B(gene name synonym)|uniprotkb:Non-structural protein 2(gene name synonym)|uniprotkb:Non-structural protein 2-3(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Non-structural protein 5A(gene name synonym)|uniprotkb:RNA-directed RNA polymerase(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:gp33(gene name synonym)|uniprotkb:gp44/48(gene name synonym)|uniprotkb:gp55(gene name synonym)|uniprotkb:Viroporin p7(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	He et al. (2014)	pubmed:24184320|imex:IM-25910	taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)")	taxid:11096(classical swine fever virus)|taxid:11096(Classical swine fever virus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-12654301|imex:IM-25910-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|refseq:NP_001132944.1|interpro:IPR029055|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR023332|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR034642	go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033897"(ribonuclease T2 activity)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044228"(host cell surface)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0070008"(serine-type exopeptidase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR042311|interpro:IPR042309|interpro:IPR042310|interpro:IPR021824|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR022120|interpro:IPR030399|interpro:IPR027417|interpro:IPR008751(Peptidase C53, pestivirus Npro)|interpro:IPR032521|interpro:IPR000280(Peptidase S31, pestivurus polyprotein NS3/p80)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR033130|interpro:IPR042542|interpro:IPR036430|rcsb pdb:5WX1|rcsb pdb:5YF5|rcsb pdb:5YF6|rcsb pdb:5YF7|rcsb pdb:5YF8|rcsb pdb:6AE4|rcsb pdb:6AE5|rcsb pdb:6AE6|rcsb pdb:6AE7|interpro:IPR043502|interpro:IPR043128	-	-	-	figure legend:table s2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2016/08/24	2016/11/30	rogid:aGPG87dLR3vAJieOc5Im2S4WlCk9823	rogid:ztG+uovVXdRDsNER3V/Xz69PFsA11096	rigid:A4p3UbIX7sWwGKvyAqS6rlJO58Q	false	-	binding-associated region:691..691-1054..1054	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:D7PRN1	uniprotkb:Q5U8X5	intact:EBI-12576543	intact:EBI-12557210	psi-mi:d7prn1_pig(display_long)|uniprotkb:IFI6(gene name)|psi-mi:IFI6(display_short)	psi-mi:q5u8x5_9flav(display_long)|uniprotkb:Capsid protein C(gene name synonym)|uniprotkb:Cysteine protease NS2(gene name synonym)|uniprotkb:"E(rns) glycoprotein"(gene name synonym)|uniprotkb:Envelope glycoprotein E1(gene name synonym)|uniprotkb:Envelope glycoprotein E2(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:N-terminal protease(gene name synonym)|uniprotkb:NS5B(gene name synonym)|uniprotkb:Non-structural protein 2(gene name synonym)|uniprotkb:Non-structural protein 2-3(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Non-structural protein 5A(gene name synonym)|uniprotkb:RNA-directed RNA polymerase(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:gp33(gene name synonym)|uniprotkb:gp44/48(gene name synonym)|uniprotkb:gp55(gene name synonym)|uniprotkb:Viroporin p7(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	He et al. (2014)	pubmed:24184320|imex:IM-25910	taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)")	taxid:11096(classical swine fever virus)|taxid:11096(Classical swine fever virus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-12654324|imex:IM-25910-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	-	go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033897"(ribonuclease T2 activity)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044228"(host cell surface)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0070008"(serine-type exopeptidase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR042311|interpro:IPR042309|interpro:IPR042310|interpro:IPR021824|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR022120|interpro:IPR030399|interpro:IPR027417|interpro:IPR008751(Peptidase C53, pestivirus Npro)|interpro:IPR032521|interpro:IPR000280(Peptidase S31, pestivurus polyprotein NS3/p80)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR033130|interpro:IPR042542|interpro:IPR036430|rcsb pdb:5WX1|rcsb pdb:5YF5|rcsb pdb:5YF6|rcsb pdb:5YF7|rcsb pdb:5YF8|rcsb pdb:6AE4|rcsb pdb:6AE5|rcsb pdb:6AE6|rcsb pdb:6AE7|interpro:IPR043502|interpro:IPR043128	-	-	-	figure legend:table s2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2016/08/24	2016/12/01	rogid:E29N/xlWS9vhlda5WJtJj4wYNms9823	rogid:ztG+uovVXdRDsNER3V/Xz69PFsA11096	rigid:TjyM7eU2rYq2XbXHRyaUOL5cI0o	false	-	binding-associated region:691..691-1054..1054	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:F1RVY7	uniprotkb:Q5U8X5	intact:EBI-12576781|ensembl:ENSSSCP00000018226	intact:EBI-12557210	psi-mi:f1rvy7_pig(display_long)|uniprotkb:GALK1(gene name)|psi-mi:GALK1(display_short)	psi-mi:q5u8x5_9flav(display_long)|uniprotkb:Capsid protein C(gene name synonym)|uniprotkb:Cysteine protease NS2(gene name synonym)|uniprotkb:"E(rns) glycoprotein"(gene name synonym)|uniprotkb:Envelope glycoprotein E1(gene name synonym)|uniprotkb:Envelope glycoprotein E2(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:N-terminal protease(gene name synonym)|uniprotkb:NS5B(gene name synonym)|uniprotkb:Non-structural protein 2(gene name synonym)|uniprotkb:Non-structural protein 2-3(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Non-structural protein 5A(gene name synonym)|uniprotkb:RNA-directed RNA polymerase(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:gp33(gene name synonym)|uniprotkb:gp44/48(gene name synonym)|uniprotkb:gp55(gene name synonym)|uniprotkb:Viroporin p7(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	He et al. (2014)	pubmed:24184320|imex:IM-25910	taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)")	taxid:11096(classical swine fever virus)|taxid:11096(Classical swine fever virus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-12654343|imex:IM-25910-25	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSSSCG00000017203(gene)|ensembl:ENSSSCT00000018728(transcript)|go:"GO:0004335"(galactokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|interpro:IPR019539|go:"GO:0006012"(galactose metabolic process)|interpro:IPR019741|interpro:IPR020568|interpro:IPR036554|interpro:IPR000705(Galactokinase)|interpro:IPR006203(GHMP kinase, ATP-binding, conserved site)|interpro:IPR006204(GHMP kinase)|interpro:IPR006206(Mevalonate and galactokinase)|interpro:IPR013750(GHMP kinase, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|refseq:XP_003131241.1	go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033897"(ribonuclease T2 activity)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044228"(host cell surface)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0070008"(serine-type exopeptidase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR042311|interpro:IPR042309|interpro:IPR042310|interpro:IPR021824|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR022120|interpro:IPR030399|interpro:IPR027417|interpro:IPR008751(Peptidase C53, pestivirus Npro)|interpro:IPR032521|interpro:IPR000280(Peptidase S31, pestivurus polyprotein NS3/p80)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR033130|interpro:IPR042542|interpro:IPR036430|rcsb pdb:5WX1|rcsb pdb:5YF5|rcsb pdb:5YF6|rcsb pdb:5YF7|rcsb pdb:5YF8|rcsb pdb:6AE4|rcsb pdb:6AE5|rcsb pdb:6AE6|rcsb pdb:6AE7|interpro:IPR043502|interpro:IPR043128	-	-	-	figure legend:table s2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2016/08/24	2017/12/04	rogid:htkeCatbHFHjR+mN6z/0ugnVcQY9823	rogid:ztG+uovVXdRDsNER3V/Xz69PFsA11096	rigid:dSaD50CuRVOE93wxGVc9c0w4iV0	false	-	binding-associated region:691..691-1054..1054	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:F1S1A8	uniprotkb:Q5U8X5	intact:EBI-12576760|ensembl:ENSSSCP00000006777	intact:EBI-12557210	psi-mi:f1s1a8_pig(display_long)|uniprotkb:NDUFS2(gene name)|psi-mi:NDUFS2(display_short)|uniprotkb:NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase 49 kDa subunit(gene name synonym)	psi-mi:q5u8x5_9flav(display_long)|uniprotkb:Capsid protein C(gene name synonym)|uniprotkb:Cysteine protease NS2(gene name synonym)|uniprotkb:"E(rns) glycoprotein"(gene name synonym)|uniprotkb:Envelope glycoprotein E1(gene name synonym)|uniprotkb:Envelope glycoprotein E2(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:N-terminal protease(gene name synonym)|uniprotkb:NS5B(gene name synonym)|uniprotkb:Non-structural protein 2(gene name synonym)|uniprotkb:Non-structural protein 2-3(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Non-structural protein 5A(gene name synonym)|uniprotkb:RNA-directed RNA polymerase(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:gp33(gene name synonym)|uniprotkb:gp44/48(gene name synonym)|uniprotkb:gp55(gene name synonym)|uniprotkb:Viroporin p7(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	He et al. (2014)	pubmed:24184320|imex:IM-25910	taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)")	taxid:11096(classical swine fever virus)|taxid:11096(Classical swine fever virus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-12654359|imex:IM-25910-27	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSSSCG00000006358(gene)|ensembl:ENSSSCT00000006967(transcript)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0042063"(gliogenesis)|go:"GO:0048038"(quinone binding)|go:"GO:0051287"(NAD binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0061351"(neural precursor cell proliferation)|go:"GO:0071453"(cellular response to oxygen levels)|interpro:IPR001135(NADH-ubiquinone oxidoreductase, chain 49kDa)|interpro:IPR014029(NADH-ubiquinone oxidoreductase, chain 49kDa, conserved site)|interpro:IPR022885|interpro:IPR029014|rcsb pdb:5GPN|rcsb pdb:5GUP|reactome:R-SSC-611105|reactome:R-SSC-6799198	go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033897"(ribonuclease T2 activity)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044228"(host cell surface)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0070008"(serine-type exopeptidase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR042311|interpro:IPR042309|interpro:IPR042310|interpro:IPR021824|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR022120|interpro:IPR030399|interpro:IPR027417|interpro:IPR008751(Peptidase C53, pestivirus Npro)|interpro:IPR032521|interpro:IPR000280(Peptidase S31, pestivurus polyprotein NS3/p80)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR033130|interpro:IPR042542|interpro:IPR036430|rcsb pdb:5WX1|rcsb pdb:5YF5|rcsb pdb:5YF6|rcsb pdb:5YF7|rcsb pdb:5YF8|rcsb pdb:6AE4|rcsb pdb:6AE5|rcsb pdb:6AE6|rcsb pdb:6AE7|interpro:IPR043502|interpro:IPR043128	-	-	-	figure legend:table s2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2016/08/24	2017/12/04	rogid:w2DTaux89QU9Tmpsqe7J+uO51S89823	rogid:ztG+uovVXdRDsNER3V/Xz69PFsA11096	rigid:db5gMg59bey8xdnWERDShvH/7XM	false	-	binding-associated region:691..691-1054..1054	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P00355	uniprotkb:Q5U8X5	intact:EBI-12576807|ensembl:ENSSSCP00005037648|ensembl:ENSSSCP00015037932|ensembl:ENSSSCP00035048787|ensembl:ENSSSCP00035048801|ensembl:ENSSSCP00040038735|ensembl:ENSSSCP00045020842|ensembl:ENSSSCP00055048878|ensembl:ENSSSCP00060024997|ensembl:ENSSSCP00065047768|ensembl:ENSSSCP00070032633|ensembl:ENSSSCP00070032639|uniprotkb:O18816|uniprotkb:P79299|uniprotkb:P79317|uniprotkb:Q29546	intact:EBI-12557210	psi-mi:g3p_pig(display_long)|uniprotkb:GAPDH(gene name)|psi-mi:GAPDH(display_short)|uniprotkb:GAPD(gene name synonym)|uniprotkb:Peptidyl-cysteine S-nitrosylase GAPDH(gene name synonym)	psi-mi:q5u8x5_9flav(display_long)|uniprotkb:Capsid protein C(gene name synonym)|uniprotkb:Cysteine protease NS2(gene name synonym)|uniprotkb:"E(rns) glycoprotein"(gene name synonym)|uniprotkb:Envelope glycoprotein E1(gene name synonym)|uniprotkb:Envelope glycoprotein E2(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:N-terminal protease(gene name synonym)|uniprotkb:NS5B(gene name synonym)|uniprotkb:Non-structural protein 2(gene name synonym)|uniprotkb:Non-structural protein 2-3(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Non-structural protein 5A(gene name synonym)|uniprotkb:RNA-directed RNA polymerase(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:gp33(gene name synonym)|uniprotkb:gp44/48(gene name synonym)|uniprotkb:gp55(gene name synonym)|uniprotkb:Viroporin p7(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	He et al. (2014)	pubmed:24184320|imex:IM-25910	taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)")	taxid:11096(classical swine fever virus)|taxid:11096(Classical swine fever virus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-12654380|imex:IM-25910-29	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSSSCG00005037806(gene)|ensembl:ENSSSCG00015069184(gene)|ensembl:ENSSSCG00035081064(gene)|ensembl:ENSSSCG00040064450(gene)|ensembl:ENSSSCG00045017499(gene)|ensembl:ENSSSCG00055030580(gene)|ensembl:ENSSSCG00060043031(gene)|ensembl:ENSSSCG00065077443(gene)|ensembl:ENSSSCG00070019692(gene)|ensembl:ENSSSCT00005060912(transcript)|ensembl:ENSSSCT00015092759(transcript)|ensembl:ENSSSCT00035111381(transcript)|ensembl:ENSSSCT00035111396(transcript)|ensembl:ENSSSCT00040088131(transcript)|ensembl:ENSSSCT00045030090(transcript)|ensembl:ENSSSCT00055060969(transcript)|ensembl:ENSSSCT00060058387(transcript)|ensembl:ENSSSCT00065107183(transcript)|ensembl:ENSSSCT00070038969(transcript)|ensembl:ENSSSCT00070038975(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0004365"("glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0006417"(regulation of translation)|go:"GO:0008017"(microtubule binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0035605"(peptidyl-cysteine S-nitrosylase activity)|go:"GO:0035606"(peptidyl-cysteine S-trans-nitrosylation)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0050661"(NADP binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051287"(NAD binding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0097452"(GAIT complex)|interpro:IPR006424(Glyceraldehyde-3-phosphate dehydrogenase, type I)|interpro:IPR020828|interpro:IPR020829|interpro:IPR020830|interpro:IPR020831|interpro:IPR036291|rcsb pdb:5DDI|rcsb pdb:5TSO|reactome:R-SSC-70171|reactome:R-SSC-70263|refseq:NP_001193288.1	go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033897"(ribonuclease T2 activity)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044228"(host cell surface)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0070008"(serine-type exopeptidase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR042311|interpro:IPR042309|interpro:IPR042310|interpro:IPR021824|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR022120|interpro:IPR030399|interpro:IPR027417|interpro:IPR008751(Peptidase C53, pestivirus Npro)|interpro:IPR032521|interpro:IPR000280(Peptidase S31, pestivurus polyprotein NS3/p80)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR033130|interpro:IPR042542|interpro:IPR036430|rcsb pdb:5WX1|rcsb pdb:5YF5|rcsb pdb:5YF6|rcsb pdb:5YF7|rcsb pdb:5YF8|rcsb pdb:6AE4|rcsb pdb:6AE5|rcsb pdb:6AE6|rcsb pdb:6AE7|interpro:IPR043502|interpro:IPR043128	-	-	-	figure legend:table s2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2016/08/24	2016/11/30	rogid:lmOZKLi1oi0tFwdISLJD0mq5KrI9823	rogid:ztG+uovVXdRDsNER3V/Xz69PFsA11096	rigid:NjMmXeBCo1ddsrCAsQ8SXYDqmdA	false	-	binding-associated region:691..691-1054..1054	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8MJ14	uniprotkb:Q5U8X5	intact:EBI-12576511	intact:EBI-12557210	psi-mi:gpx1_pig(display_long)|uniprotkb:GPX1(gene name)|psi-mi:GPX1(display_short)|uniprotkb:Cellular glutathione peroxidase(gene name synonym)	psi-mi:q5u8x5_9flav(display_long)|uniprotkb:Capsid protein C(gene name synonym)|uniprotkb:Cysteine protease NS2(gene name synonym)|uniprotkb:"E(rns) glycoprotein"(gene name synonym)|uniprotkb:Envelope glycoprotein E1(gene name synonym)|uniprotkb:Envelope glycoprotein E2(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:N-terminal protease(gene name synonym)|uniprotkb:NS5B(gene name synonym)|uniprotkb:Non-structural protein 2(gene name synonym)|uniprotkb:Non-structural protein 2-3(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Non-structural protein 5A(gene name synonym)|uniprotkb:RNA-directed RNA polymerase(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:gp33(gene name synonym)|uniprotkb:gp44/48(gene name synonym)|uniprotkb:gp55(gene name synonym)|uniprotkb:Viroporin p7(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	He et al. (2014)	pubmed:24184320|imex:IM-25910	taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)")	taxid:11096(classical swine fever virus)|taxid:11096(Classical swine fever virus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-12654400|imex:IM-25910-31	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0004601"(peroxidase activity)|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0010269"(response to selenium ion)|go:"GO:0019372"(lipoxygenase pathway)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0047066"(phospholipid-hydroperoxide glutathione peroxidase activity)|go:"GO:0019369"(arachidonic acid metabolic process)|refseq:NP_999366.1|interpro:IPR000889(Glutathione peroxidase)|interpro:IPR029759|interpro:IPR029760|interpro:IPR036249	go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033897"(ribonuclease T2 activity)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044228"(host cell surface)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0070008"(serine-type exopeptidase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR042311|interpro:IPR042309|interpro:IPR042310|interpro:IPR021824|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR022120|interpro:IPR030399|interpro:IPR027417|interpro:IPR008751(Peptidase C53, pestivirus Npro)|interpro:IPR032521|interpro:IPR000280(Peptidase S31, pestivurus polyprotein NS3/p80)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR033130|interpro:IPR042542|interpro:IPR036430|rcsb pdb:5WX1|rcsb pdb:5YF5|rcsb pdb:5YF6|rcsb pdb:5YF7|rcsb pdb:5YF8|rcsb pdb:6AE4|rcsb pdb:6AE5|rcsb pdb:6AE6|rcsb pdb:6AE7|interpro:IPR043502|interpro:IPR043128	-	-	-	figure legend:table s2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2016/08/24	2016/11/30	rogid:sPQHn/oRIeOXpz2NTg8LiTmwu0w9823	rogid:ztG+uovVXdRDsNER3V/Xz69PFsA11096	rigid:tq4ea+kLYk7K69JTvigcOfDE5vQ	false	-	binding-associated region:691..691-1054..1054	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:I3L928	uniprotkb:Q5U8X5	intact:EBI-12576679|ensembl:ENSSSCP00000020539	intact:EBI-12557210	psi-mi:i3l928_pig(display_long)|uniprotkb:THOC6(gene name)|psi-mi:THOC6(display_short)	psi-mi:q5u8x5_9flav(display_long)|uniprotkb:Capsid protein C(gene name synonym)|uniprotkb:Cysteine protease NS2(gene name synonym)|uniprotkb:"E(rns) glycoprotein"(gene name synonym)|uniprotkb:Envelope glycoprotein E1(gene name synonym)|uniprotkb:Envelope glycoprotein E2(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:N-terminal protease(gene name synonym)|uniprotkb:NS5B(gene name synonym)|uniprotkb:Non-structural protein 2(gene name synonym)|uniprotkb:Non-structural protein 2-3(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Non-structural protein 5A(gene name synonym)|uniprotkb:RNA-directed RNA polymerase(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:gp33(gene name synonym)|uniprotkb:gp44/48(gene name synonym)|uniprotkb:gp55(gene name synonym)|uniprotkb:Viroporin p7(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	He et al. (2014)	pubmed:24184320|imex:IM-25910	taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)")	taxid:11096(classical swine fever virus)|taxid:11096(Classical swine fever virus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-12654418|imex:IM-25910-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSSSCG00000023315(gene)|ensembl:ENSSSCT00000026356(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0006397"(mRNA processing)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR042626	go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033897"(ribonuclease T2 activity)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044228"(host cell surface)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0070008"(serine-type exopeptidase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR042311|interpro:IPR042309|interpro:IPR042310|interpro:IPR021824|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR022120|interpro:IPR030399|interpro:IPR027417|interpro:IPR008751(Peptidase C53, pestivirus Npro)|interpro:IPR032521|interpro:IPR000280(Peptidase S31, pestivurus polyprotein NS3/p80)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR033130|interpro:IPR042542|interpro:IPR036430|rcsb pdb:5WX1|rcsb pdb:5YF5|rcsb pdb:5YF6|rcsb pdb:5YF7|rcsb pdb:5YF8|rcsb pdb:6AE4|rcsb pdb:6AE5|rcsb pdb:6AE6|rcsb pdb:6AE7|interpro:IPR043502|interpro:IPR043128	-	-	-	figure legend:table s2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2016/08/24	2017/12/04	rogid:mNl4s9izSMIpF9zRFnIOzLxq3A49823	rogid:ztG+uovVXdRDsNER3V/Xz69PFsA11096	rigid:GUF/e9F6r7/wzCMqsM7Amn3NVjc	false	-	binding-associated region:691..691-1054..1054	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:I3LE95	uniprotkb:Q5U8X5	intact:EBI-12576523|ensembl:ENSSSCP00000022381	intact:EBI-12557210	psi-mi:i3le95_pig(display_long)|uniprotkb:DCP1B(gene name)|psi-mi:DCP1B(display_short)	psi-mi:q5u8x5_9flav(display_long)|uniprotkb:Capsid protein C(gene name synonym)|uniprotkb:Cysteine protease NS2(gene name synonym)|uniprotkb:"E(rns) glycoprotein"(gene name synonym)|uniprotkb:Envelope glycoprotein E1(gene name synonym)|uniprotkb:Envelope glycoprotein E2(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:N-terminal protease(gene name synonym)|uniprotkb:NS5B(gene name synonym)|uniprotkb:Non-structural protein 2(gene name synonym)|uniprotkb:Non-structural protein 2-3(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Non-structural protein 5A(gene name synonym)|uniprotkb:RNA-directed RNA polymerase(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:gp33(gene name synonym)|uniprotkb:gp44/48(gene name synonym)|uniprotkb:gp55(gene name synonym)|uniprotkb:Viroporin p7(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	He et al. (2014)	pubmed:24184320|imex:IM-25910	taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)")	taxid:11096(classical swine fever virus)|taxid:11096(Classical swine fever virus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-12654424|imex:IM-25910-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSSSCG00000023976(gene)|ensembl:ENSSSCT00000028544(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR010334(Dcp1-like decapping)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR031953|reactome:R-SSC-430039	go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033897"(ribonuclease T2 activity)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044228"(host cell surface)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0070008"(serine-type exopeptidase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR042311|interpro:IPR042309|interpro:IPR042310|interpro:IPR021824|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR022120|interpro:IPR030399|interpro:IPR027417|interpro:IPR008751(Peptidase C53, pestivirus Npro)|interpro:IPR032521|interpro:IPR000280(Peptidase S31, pestivurus polyprotein NS3/p80)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR033130|interpro:IPR042542|interpro:IPR036430|rcsb pdb:5WX1|rcsb pdb:5YF5|rcsb pdb:5YF6|rcsb pdb:5YF7|rcsb pdb:5YF8|rcsb pdb:6AE4|rcsb pdb:6AE5|rcsb pdb:6AE6|rcsb pdb:6AE7|interpro:IPR043502|interpro:IPR043128	-	-	-	figure legend:table s2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2016/08/24	2017/12/04	rogid:CSGvgzKBMCJxhFC7j0DtKZlsws49823	rogid:ztG+uovVXdRDsNER3V/Xz69PFsA11096	rigid:3H4XCN6HTVRa2zwg6eYOu4mMxEk	false	-	binding-associated region:691..691-1054..1054	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:I3LII3	uniprotkb:Q5U8X5	intact:EBI-12576548|ensembl:ENSSSCP00000023888	intact:EBI-12557210	psi-mi:i3lii3_pig(display_long)|uniprotkb:EEF2(gene name)|psi-mi:EEF2(display_short)	psi-mi:q5u8x5_9flav(display_long)|uniprotkb:Capsid protein C(gene name synonym)|uniprotkb:Cysteine protease NS2(gene name synonym)|uniprotkb:"E(rns) glycoprotein"(gene name synonym)|uniprotkb:Envelope glycoprotein E1(gene name synonym)|uniprotkb:Envelope glycoprotein E2(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:N-terminal protease(gene name synonym)|uniprotkb:NS5B(gene name synonym)|uniprotkb:Non-structural protein 2(gene name synonym)|uniprotkb:Non-structural protein 2-3(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Non-structural protein 5A(gene name synonym)|uniprotkb:RNA-directed RNA polymerase(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:gp33(gene name synonym)|uniprotkb:gp44/48(gene name synonym)|uniprotkb:gp55(gene name synonym)|uniprotkb:Viroporin p7(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	He et al. (2014)	pubmed:24184320|imex:IM-25910	taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)")	taxid:11096(classical swine fever virus)|taxid:11096(Classical swine fever virus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-12654430|imex:IM-25910-33	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSSSCG00000025675(gene)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006414"(translational elongation)|go:"GO:0016235"(aggresome)|ensembl:ENSSSCT00000031794(transcript)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043022"(ribosome binding)|go:"GO:0045202"(synapse)|go:"GO:0045727"(positive regulation of translation)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR005517(Translation elongation factor EFG/EF2, domain IV)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR020568|interpro:IPR027417|interpro:IPR031157|interpro:IPR035647|interpro:IPR041095|reactome:R-SSC-156902|reactome:R-SSC-5358493|reactome:R-SSC-6798695|interpro:IPR005225(Small GTP-binding protein)	go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033897"(ribonuclease T2 activity)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044228"(host cell surface)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0070008"(serine-type exopeptidase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR042311|interpro:IPR042309|interpro:IPR042310|interpro:IPR021824|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR022120|interpro:IPR030399|interpro:IPR027417|interpro:IPR008751(Peptidase C53, pestivirus Npro)|interpro:IPR032521|interpro:IPR000280(Peptidase S31, pestivurus polyprotein NS3/p80)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR033130|interpro:IPR042542|interpro:IPR036430|rcsb pdb:5WX1|rcsb pdb:5YF5|rcsb pdb:5YF6|rcsb pdb:5YF7|rcsb pdb:5YF8|rcsb pdb:6AE4|rcsb pdb:6AE5|rcsb pdb:6AE6|rcsb pdb:6AE7|interpro:IPR043502|interpro:IPR043128	-	-	-	figure legend:table s2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2016/08/24	2020/01/08	rogid:p8pEHqXwSg5r9/ywbRwUAsdyEDM9823	rogid:ztG+uovVXdRDsNER3V/Xz69PFsA11096	rigid:XwmenREnlk2wSCqOIQn86b7BtUA	false	-	binding-associated region:691..691-1054..1054	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:I3LK59	uniprotkb:Q5U8X5	intact:EBI-12576701|ensembl:ENSSSCP00000024473	intact:EBI-12557210	psi-mi:i3lk59_pig(display_long)|uniprotkb:ENO1(gene name)|psi-mi:ENO1(display_short)	psi-mi:q5u8x5_9flav(display_long)|uniprotkb:Capsid protein C(gene name synonym)|uniprotkb:Cysteine protease NS2(gene name synonym)|uniprotkb:"E(rns) glycoprotein"(gene name synonym)|uniprotkb:Envelope glycoprotein E1(gene name synonym)|uniprotkb:Envelope glycoprotein E2(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:N-terminal protease(gene name synonym)|uniprotkb:NS5B(gene name synonym)|uniprotkb:Non-structural protein 2(gene name synonym)|uniprotkb:Non-structural protein 2-3(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Non-structural protein 5A(gene name synonym)|uniprotkb:RNA-directed RNA polymerase(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:gp33(gene name synonym)|uniprotkb:gp44/48(gene name synonym)|uniprotkb:gp55(gene name synonym)|uniprotkb:Viroporin p7(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	He et al. (2014)	pubmed:24184320|imex:IM-25910	taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)")	taxid:11096(classical swine fever virus)|taxid:11096(Classical swine fever virus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-12654436|imex:IM-25910-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSSSCG00000022343(gene)|ensembl:ENSSSCT00000026917(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0006096"(glycolytic process)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849	go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033897"(ribonuclease T2 activity)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044228"(host cell surface)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0070008"(serine-type exopeptidase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR042311|interpro:IPR042309|interpro:IPR042310|interpro:IPR021824|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR022120|interpro:IPR030399|interpro:IPR027417|interpro:IPR008751(Peptidase C53, pestivirus Npro)|interpro:IPR032521|interpro:IPR000280(Peptidase S31, pestivurus polyprotein NS3/p80)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR033130|interpro:IPR042542|interpro:IPR036430|rcsb pdb:5WX1|rcsb pdb:5YF5|rcsb pdb:5YF6|rcsb pdb:5YF7|rcsb pdb:5YF8|rcsb pdb:6AE4|rcsb pdb:6AE5|rcsb pdb:6AE6|rcsb pdb:6AE7|interpro:IPR043502|interpro:IPR043128	-	-	-	figure legend:table s2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2016/08/24	2020/01/08	rogid:GQA1ix6DmchQjnyUwcV5xLxP6gA9823	rogid:ztG+uovVXdRDsNER3V/Xz69PFsA11096	rigid:dtm9IL8eCEo6meLR0z2rqcqTVhY	false	-	binding-associated region:691..691-1054..1054	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
intact:EBI-9523431	uniprotkb:Q5U8X5	-	intact:EBI-12557210	psi-mi:i3lnl6_pig(display_short)|psi-mi:EBI-9523431(display_long)	psi-mi:q5u8x5_9flav(display_long)|uniprotkb:Capsid protein C(gene name synonym)|uniprotkb:Cysteine protease NS2(gene name synonym)|uniprotkb:"E(rns) glycoprotein"(gene name synonym)|uniprotkb:Envelope glycoprotein E1(gene name synonym)|uniprotkb:Envelope glycoprotein E2(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:N-terminal protease(gene name synonym)|uniprotkb:NS5B(gene name synonym)|uniprotkb:Non-structural protein 2(gene name synonym)|uniprotkb:Non-structural protein 2-3(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Non-structural protein 5A(gene name synonym)|uniprotkb:RNA-directed RNA polymerase(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:gp33(gene name synonym)|uniprotkb:gp44/48(gene name synonym)|uniprotkb:gp55(gene name synonym)|uniprotkb:Viroporin p7(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	He et al. (2014)	pubmed:24184320|imex:IM-25910	taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)")	taxid:11096(classical swine fever virus)|taxid:11096(Classical swine fever virus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-12654442|imex:IM-25910-35	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:I3LNL6(uniprot-removed-ac)	go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033897"(ribonuclease T2 activity)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044228"(host cell surface)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0070008"(serine-type exopeptidase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR042311|interpro:IPR042309|interpro:IPR042310|interpro:IPR021824|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR022120|interpro:IPR030399|interpro:IPR027417|interpro:IPR008751(Peptidase C53, pestivirus Npro)|interpro:IPR032521|interpro:IPR000280(Peptidase S31, pestivurus polyprotein NS3/p80)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR033130|interpro:IPR042542|interpro:IPR036430|rcsb pdb:5WX1|rcsb pdb:5YF5|rcsb pdb:5YF6|rcsb pdb:5YF7|rcsb pdb:5YF8|rcsb pdb:6AE4|rcsb pdb:6AE5|rcsb pdb:6AE6|rcsb pdb:6AE7|interpro:IPR043502|interpro:IPR043128	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	figure legend:table s2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2016/08/24	2016/11/30	rogid:r9YHhVPDWEMpeTt/kWuMi7Yd5ew9823	rogid:ztG+uovVXdRDsNER3V/Xz69PFsA11096	rigid:Iz6BYAcb6nhjDoFm5b98CkRzD/c	false	-	binding-associated region:691..691-1054..1054	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
intact:EBI-12576842	uniprotkb:Q5U8X5	-	intact:EBI-12557210	psi-mi:mp2k2_pig(display_short)|psi-mi:EBI-12576842(display_long)	psi-mi:q5u8x5_9flav(display_long)|uniprotkb:Capsid protein C(gene name synonym)|uniprotkb:Cysteine protease NS2(gene name synonym)|uniprotkb:"E(rns) glycoprotein"(gene name synonym)|uniprotkb:Envelope glycoprotein E1(gene name synonym)|uniprotkb:Envelope glycoprotein E2(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:N-terminal protease(gene name synonym)|uniprotkb:NS5B(gene name synonym)|uniprotkb:Non-structural protein 2(gene name synonym)|uniprotkb:Non-structural protein 2-3(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Non-structural protein 5A(gene name synonym)|uniprotkb:RNA-directed RNA polymerase(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:gp33(gene name synonym)|uniprotkb:gp44/48(gene name synonym)|uniprotkb:gp55(gene name synonym)|uniprotkb:Viroporin p7(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	He et al. (2014)	pubmed:24184320|imex:IM-25910	taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)")	taxid:11096(classical swine fever virus)|taxid:11096(Classical swine fever virus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-12654448|imex:IM-25910-15	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	-	go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033897"(ribonuclease T2 activity)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044228"(host cell surface)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0070008"(serine-type exopeptidase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR042311|interpro:IPR042309|interpro:IPR042310|interpro:IPR021824|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR022120|interpro:IPR030399|interpro:IPR027417|interpro:IPR008751(Peptidase C53, pestivirus Npro)|interpro:IPR032521|interpro:IPR000280(Peptidase S31, pestivurus polyprotein NS3/p80)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR033130|interpro:IPR042542|interpro:IPR036430|rcsb pdb:5WX1|rcsb pdb:5YF5|rcsb pdb:5YF6|rcsb pdb:5YF7|rcsb pdb:5YF8|rcsb pdb:6AE4|rcsb pdb:6AE5|rcsb pdb:6AE6|rcsb pdb:6AE7|interpro:IPR043502|interpro:IPR043128	-	-	-	figure legend:table s2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2016/08/24	2016/11/30	-	rogid:ztG+uovVXdRDsNER3V/Xz69PFsA11096	-	false	-	binding-associated region:691..691-1054..1054	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P62197	uniprotkb:Q5U8X5	intact:EBI-12576584|ensembl:ENSSSCP00005001507|ensembl:ENSSSCP00015027070|ensembl:ENSSSCP00035001339|ensembl:ENSSSCP00045032771|ensembl:ENSSSCP00060041515|ensembl:ENSSSCP00070008632|uniprotkb:O35051|uniprotkb:P47210|uniprotkb:P52915|uniprotkb:P52916	intact:EBI-12557210	psi-mi:prs8_pig(display_long)|uniprotkb:PSMC5(gene name)|psi-mi:PSMC5(display_short)|uniprotkb:26S proteasome AAA-ATPase subunit RPT6(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 5(gene name synonym)|uniprotkb:Proteasome subunit p45(gene name synonym)|uniprotkb:Tat-binding protein homolog 10(gene name synonym)|uniprotkb:p45/SUG(gene name synonym)	psi-mi:q5u8x5_9flav(display_long)|uniprotkb:Capsid protein C(gene name synonym)|uniprotkb:Cysteine protease NS2(gene name synonym)|uniprotkb:"E(rns) glycoprotein"(gene name synonym)|uniprotkb:Envelope glycoprotein E1(gene name synonym)|uniprotkb:Envelope glycoprotein E2(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:N-terminal protease(gene name synonym)|uniprotkb:NS5B(gene name synonym)|uniprotkb:Non-structural protein 2(gene name synonym)|uniprotkb:Non-structural protein 2-3(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Non-structural protein 5A(gene name synonym)|uniprotkb:RNA-directed RNA polymerase(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:gp33(gene name synonym)|uniprotkb:gp44/48(gene name synonym)|uniprotkb:gp55(gene name synonym)|uniprotkb:Viroporin p7(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	He et al. (2014)	pubmed:24184320|imex:IM-25910	taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)")	taxid:11096(classical swine fever virus)|taxid:11096(Classical swine fever virus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-12654454|imex:IM-25910-47	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSSSCG00005001713(gene)|ensembl:ENSSSCG00015050234(gene)|ensembl:ENSSSCG00035003144(gene)|ensembl:ENSSSCG00045027586(gene)|ensembl:ENSSSCG00060070251(gene)|ensembl:ENSSSCG00070005507(gene)|ensembl:ENSSSCT00005002597(transcript)|ensembl:ENSSSCT00015067608(transcript)|ensembl:ENSSSCT00035003982(transcript)|ensembl:ENSSSCT00060095990(transcript)|ensembl:ENSSSCT00070010510(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0031531"(thyrotropin-releasing hormone receptor binding)|go:"GO:0031595"(nuclear proteasome complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0098794"(postsynapse)|go:"GO:0140296"(general transcription initiation factor binding)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|reactome:R-SSC-1169091|reactome:R-SSC-1234176|reactome:R-SSC-1236978|reactome:R-SSC-174084|reactome:R-SSC-174154|reactome:R-SSC-174178|reactome:R-SSC-174184|reactome:R-SSC-195253|reactome:R-SSC-202424|reactome:R-SSC-2467813|reactome:R-SSC-2871837|reactome:R-SSC-349425|reactome:R-SSC-350562|ensembl:ENSSSCT00045047189(transcript)|reactome:R-SSC-450408|reactome:R-SSC-4608870|reactome:R-SSC-4641257|reactome:R-SSC-4641258|reactome:R-SSC-5358346|reactome:R-SSC-5607761|reactome:R-SSC-5607764|reactome:R-SSC-5610780|reactome:R-SSC-5610785|reactome:R-SSC-5632684|reactome:R-SSC-5658442|reactome:R-SSC-5668541|reactome:R-SSC-5676590|reactome:R-SSC-5687128|reactome:R-SSC-5689603|reactome:R-SSC-5689880|reactome:R-SSC-68827|reactome:R-SSC-68949|reactome:R-SSC-69017|reactome:R-SSC-382556|reactome:R-SSC-69601|reactome:R-SSC-75815|reactome:R-SSC-8852276|reactome:R-SSC-8854050|reactome:R-SSC-8932339|reactome:R-SSC-8939236|reactome:R-SSC-8939902|reactome:R-SSC-8941858|reactome:R-SSC-8948751|reactome:R-SSC-8951664|reactome:R-SSC-9020702|reactome:R-SSC-983168|reactome:R-SSC-69481|refseq:NP_999148.1	go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033897"(ribonuclease T2 activity)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044228"(host cell surface)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0070008"(serine-type exopeptidase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR042311|interpro:IPR042309|interpro:IPR042310|interpro:IPR021824|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR022120|interpro:IPR030399|interpro:IPR027417|interpro:IPR008751(Peptidase C53, pestivirus Npro)|interpro:IPR032521|interpro:IPR000280(Peptidase S31, pestivurus polyprotein NS3/p80)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR033130|interpro:IPR042542|interpro:IPR036430|rcsb pdb:5WX1|rcsb pdb:5YF5|rcsb pdb:5YF6|rcsb pdb:5YF7|rcsb pdb:5YF8|rcsb pdb:6AE4|rcsb pdb:6AE5|rcsb pdb:6AE6|rcsb pdb:6AE7|interpro:IPR043502|interpro:IPR043128	-	-	-	figure legend:table s2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2016/08/24	2016/11/30	rogid:zgUTOX/O4m86U/Nf+pnT7u0m0gY9823	rogid:ztG+uovVXdRDsNER3V/Xz69PFsA11096	rigid:D62E7l90DVn3bKmNezgHRk6785I	false	-	binding-associated region:691..691-1054..1054	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q2YHQ3	uniprotkb:Q5U8X5	intact:EBI-779542	intact:EBI-12557210	psi-mi:q2yhq3_pig(display_long)|uniprotkb:FLNA(gene name)|psi-mi:FLNA(display_short)	psi-mi:q5u8x5_9flav(display_long)|uniprotkb:Capsid protein C(gene name synonym)|uniprotkb:Cysteine protease NS2(gene name synonym)|uniprotkb:"E(rns) glycoprotein"(gene name synonym)|uniprotkb:Envelope glycoprotein E1(gene name synonym)|uniprotkb:Envelope glycoprotein E2(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:N-terminal protease(gene name synonym)|uniprotkb:NS5B(gene name synonym)|uniprotkb:Non-structural protein 2(gene name synonym)|uniprotkb:Non-structural protein 2-3(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Non-structural protein 5A(gene name synonym)|uniprotkb:RNA-directed RNA polymerase(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:gp33(gene name synonym)|uniprotkb:gp44/48(gene name synonym)|uniprotkb:gp55(gene name synonym)|uniprotkb:Viroporin p7(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	He et al. (2014)	pubmed:24184320|imex:IM-25910	taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)")	taxid:11096(classical swine fever virus)|taxid:11096(Classical swine fever virus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-12654460|imex:IM-25910-37	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR017868|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0051015"(actin filament binding)|interpro:IPR044801	go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033897"(ribonuclease T2 activity)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044228"(host cell surface)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0070008"(serine-type exopeptidase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR042311|interpro:IPR042309|interpro:IPR042310|interpro:IPR021824|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR022120|interpro:IPR030399|interpro:IPR027417|interpro:IPR008751(Peptidase C53, pestivirus Npro)|interpro:IPR032521|interpro:IPR000280(Peptidase S31, pestivurus polyprotein NS3/p80)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR033130|interpro:IPR042542|interpro:IPR036430|rcsb pdb:5WX1|rcsb pdb:5YF5|rcsb pdb:5YF6|rcsb pdb:5YF7|rcsb pdb:5YF8|rcsb pdb:6AE4|rcsb pdb:6AE5|rcsb pdb:6AE6|rcsb pdb:6AE7|interpro:IPR043502|interpro:IPR043128	-	-	-	figure legend:table s2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2016/08/24	2016/11/30	rogid:DMEOGUmEtiVpMKbJIGKuvDe8DXc9823	rogid:ztG+uovVXdRDsNER3V/Xz69PFsA11096	rigid:osisaypnZ5Pom6zDdTRaShFBSZo	false	-	binding-associated region:691..691-1054..1054	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9TSW1	uniprotkb:Q5U8X5	intact:EBI-12576492	intact:EBI-12557210	psi-mi:q9tsw1_pig(display_long)|uniprotkb:SLA-2(gene name)|psi-mi:SLA-2(display_short)	psi-mi:q5u8x5_9flav(display_long)|uniprotkb:Capsid protein C(gene name synonym)|uniprotkb:Cysteine protease NS2(gene name synonym)|uniprotkb:"E(rns) glycoprotein"(gene name synonym)|uniprotkb:Envelope glycoprotein E1(gene name synonym)|uniprotkb:Envelope glycoprotein E2(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:N-terminal protease(gene name synonym)|uniprotkb:NS5B(gene name synonym)|uniprotkb:Non-structural protein 2(gene name synonym)|uniprotkb:Non-structural protein 2-3(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Non-structural protein 5A(gene name synonym)|uniprotkb:RNA-directed RNA polymerase(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:gp33(gene name synonym)|uniprotkb:gp44/48(gene name synonym)|uniprotkb:gp55(gene name synonym)|uniprotkb:Viroporin p7(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	He et al. (2014)	pubmed:24184320|imex:IM-25910	taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)")	taxid:11096(classical swine fever virus)|taxid:11096(Classical swine fever virus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-12654466|imex:IM-25910-39	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0006955"(immune response)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019882"(antigen processing and presentation)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR010579(MHC class I, alpha chain, C-terminal)|interpro:IPR036179|interpro:IPR037055	go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033897"(ribonuclease T2 activity)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044228"(host cell surface)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0070008"(serine-type exopeptidase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR042311|interpro:IPR042309|interpro:IPR042310|interpro:IPR021824|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR022120|interpro:IPR030399|interpro:IPR027417|interpro:IPR008751(Peptidase C53, pestivirus Npro)|interpro:IPR032521|interpro:IPR000280(Peptidase S31, pestivurus polyprotein NS3/p80)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR033130|interpro:IPR042542|interpro:IPR036430|rcsb pdb:5WX1|rcsb pdb:5YF5|rcsb pdb:5YF6|rcsb pdb:5YF7|rcsb pdb:5YF8|rcsb pdb:6AE4|rcsb pdb:6AE5|rcsb pdb:6AE6|rcsb pdb:6AE7|interpro:IPR043502|interpro:IPR043128	-	-	-	figure legend:table s2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2016/08/24	2016/11/30	rogid:tlOTKtXfum4rKpygTjN8kHAg5GE9823	rogid:ztG+uovVXdRDsNER3V/Xz69PFsA11096	rigid:6KghrtGfPg+Q5Rinm7BE2/6k8lI	false	-	binding-associated region:691..691-1054..1054	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P63246	uniprotkb:Q5U8X5	intact:EBI-12515485|ensembl:ENSSSCP00000023723|ensembl:ENSSSCP00005040753|ensembl:ENSSSCP00015037908|ensembl:ENSSSCP00025036753|ensembl:ENSSSCP00030020404|ensembl:ENSSSCP00035045285|ensembl:ENSSSCP00040026390|ensembl:ENSSSCP00045006795|ensembl:ENSSSCP00050041781|ensembl:ENSSSCP00055034861|ensembl:ENSSSCP00060002097|ensembl:ENSSSCP00070022091|ensembl:ENSSSCP00065036048|uniprotkb:P25388|uniprotkb:P99049	intact:EBI-12557210	psi-mi:rack1_pig(display_long)|uniprotkb:RACK1(gene name)|psi-mi:RACK1(display_short)|uniprotkb:GNB2L1(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein subunit beta-2-like 1(gene name synonym)|uniprotkb:Receptor for activated C kinase(gene name synonym)|uniprotkb:Receptor of activated protein kinase C 1(gene name synonym)	psi-mi:q5u8x5_9flav(display_long)|uniprotkb:Capsid protein C(gene name synonym)|uniprotkb:Cysteine protease NS2(gene name synonym)|uniprotkb:"E(rns) glycoprotein"(gene name synonym)|uniprotkb:Envelope glycoprotein E1(gene name synonym)|uniprotkb:Envelope glycoprotein E2(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:N-terminal protease(gene name synonym)|uniprotkb:NS5B(gene name synonym)|uniprotkb:Non-structural protein 2(gene name synonym)|uniprotkb:Non-structural protein 2-3(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Non-structural protein 5A(gene name synonym)|uniprotkb:RNA-directed RNA polymerase(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:gp33(gene name synonym)|uniprotkb:gp44/48(gene name synonym)|uniprotkb:gp55(gene name synonym)|uniprotkb:Viroporin p7(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	He et al. (2014)	pubmed:24184320|imex:IM-25910	taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)")	taxid:11096(classical swine fever virus)|taxid:11096(Classical swine fever virus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-12654472|imex:IM-25910-49	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSSSCG00000029724(gene)|ensembl:ENSSSCG00005041028(gene)|ensembl:ENSSSCG00015067931(gene)|ensembl:ENSSSCG00025061587(gene)|ensembl:ENSSSCG00030032752(gene)|ensembl:ENSSSCG00035076782(gene)|ensembl:ENSSSCG00040046413(gene)|ensembl:ENSSSCG00045005934(gene)|ensembl:ENSSSCG00050071078(gene)|ensembl:ENSSSCG00055022149(gene)|ensembl:ENSSSCG00060004937(gene)|ensembl:ENSSSCG00065060348(gene)|ensembl:ENSSSCG00070013602(gene)|ensembl:ENSSSCT00000022602(transcript)|ensembl:ENSSSCT00005065854(transcript)|ensembl:ENSSSCT00015092717(transcript)|ensembl:ENSSSCT00025084487(transcript)|ensembl:ENSSSCT00030045369(transcript)|ensembl:ENSSSCT00035105457(transcript)|ensembl:ENSSSCT00040062588(transcript)|ensembl:ENSSSCT00045009969(transcript)|ensembl:ENSSSCT00050096955(transcript)|ensembl:ENSSSCT00055043778(transcript)|ensembl:ENSSSCT00060006171(transcript)|ensembl:ENSSSCT00065082735(transcript)|ensembl:ENSSSCT00070026581(transcript)|go:"GO:0001891"(phagocytic cup)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0007049"(cell cycle)|go:"GO:0007369"(gastrulation)|go:"GO:0008656"(cysteine-type endopeptidase activator activity involved in apoptotic process)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030496"(midbody)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042998"(positive regulation of Golgi to plasma membrane protein transport)|go:"GO:0043022"(ribosome binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043204"(perikaryon)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048511"(rhythmic process)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0051302"(regulation of cell division)|go:"GO:0051343"(positive regulation of cyclic-nucleotide phosphodiesterase activity)|go:"GO:0051434"(BH3 domain binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0051901"(positive regulation of mitochondrial depolarization)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0030292"(protein tyrosine kinase inhibitor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030332"(cyclin binding)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030425"(dendrite)|go:"GO:0072344"(rescue of stalled ribosome)|go:"GO:1903208"(negative regulation of hydrogen peroxide-induced neuron death)|go:"GO:1990630"(IRE1-RACK1-PP2A complex)|go:"GO:2000114"(regulation of establishment of cell polarity)|go:"GO:2000543"(positive regulation of gastrulation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|rcsb pdb:3J7P|rcsb pdb:3J7R|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|refseq:NP_999497.1	go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033897"(ribonuclease T2 activity)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044228"(host cell surface)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0070008"(serine-type exopeptidase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR042311|interpro:IPR042309|interpro:IPR042310|interpro:IPR021824|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR022120|interpro:IPR030399|interpro:IPR027417|interpro:IPR008751(Peptidase C53, pestivirus Npro)|interpro:IPR032521|interpro:IPR000280(Peptidase S31, pestivurus polyprotein NS3/p80)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR033130|interpro:IPR042542|interpro:IPR036430|rcsb pdb:5WX1|rcsb pdb:5YF5|rcsb pdb:5YF6|rcsb pdb:5YF7|rcsb pdb:5YF8|rcsb pdb:6AE4|rcsb pdb:6AE5|rcsb pdb:6AE6|rcsb pdb:6AE7|interpro:IPR043502|interpro:IPR043128	-	-	-	figure legend:table s2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2016/08/24	2016/11/30	rogid:LXHlhPtxUzHJNncoPteGw2iXsFg9823	rogid:ztG+uovVXdRDsNER3V/Xz69PFsA11096	rigid:JSWBJarSRTv6G6X2B8i8UZz5Jzg	false	-	binding-associated region:691..691-1054..1054	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P62901	uniprotkb:Q5U8X5	intact:EBI-12576655|ensembl:ENSSSCP00000008721|ensembl:ENSSSCP00015035169|ensembl:ENSSSCP00040008472|ensembl:ENSSSCP00050003248|ensembl:ENSSSCP00055009096|ensembl:ENSSSCP00060009652|ensembl:ENSSSCP00065037487|ensembl:ENSSSCP00070048274|ensembl:ENSSSCP00070048278|ensembl:ENSSSCP00005010579|uniprotkb:P12947	intact:EBI-12557210	psi-mi:rl31_pig(display_long)|uniprotkb:RPL31(gene name)|psi-mi:RPL31(display_short)	psi-mi:q5u8x5_9flav(display_long)|uniprotkb:Capsid protein C(gene name synonym)|uniprotkb:Cysteine protease NS2(gene name synonym)|uniprotkb:"E(rns) glycoprotein"(gene name synonym)|uniprotkb:Envelope glycoprotein E1(gene name synonym)|uniprotkb:Envelope glycoprotein E2(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:N-terminal protease(gene name synonym)|uniprotkb:NS5B(gene name synonym)|uniprotkb:Non-structural protein 2(gene name synonym)|uniprotkb:Non-structural protein 2-3(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Non-structural protein 5A(gene name synonym)|uniprotkb:RNA-directed RNA polymerase(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:gp33(gene name synonym)|uniprotkb:gp44/48(gene name synonym)|uniprotkb:gp55(gene name synonym)|uniprotkb:Viroporin p7(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	He et al. (2014)	pubmed:24184320|imex:IM-25910	taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)")	taxid:11096(classical swine fever virus)|taxid:11096(Classical swine fever virus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-12654478|imex:IM-25910-17	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSSSCG00000008170(gene)|ensembl:ENSSSCG00005011322(gene)|ensembl:ENSSSCG00015064583(gene)|ensembl:ENSSSCG00040015050(gene)|ensembl:ENSSSCG00050005659(gene)|ensembl:ENSSSCG00055005900(gene)|ensembl:ENSSSCG00060017323(gene)|ensembl:ENSSSCG00065062508(gene)|ensembl:ENSSSCG00070028304(gene)|ensembl:ENSSSCT00000008947(transcript)|ensembl:ENSSSCT00005017698(transcript)|ensembl:ENSSSCT00015086465(transcript)|ensembl:ENSSSCT00040020244(transcript)|ensembl:ENSSSCT00050007682(transcript)|ensembl:ENSSSCT00055011499(transcript)|ensembl:ENSSSCT00060023161(transcript)|ensembl:ENSSSCT00065085759(transcript)|ensembl:ENSSSCT00070056817(transcript)|ensembl:ENSSSCT00070056821(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0015934"(large ribosomal subunit)|go:"GO:0022625"(cytosolic large ribosomal subunit)|interpro:IPR000054(Ribosomal protein L31e)|interpro:IPR020052|interpro:IPR023621|rcsb pdb:3J7O|rcsb pdb:3J7P|rcsb pdb:3J7Q|rcsb pdb:3J7R|reactome:R-SSC-156827|reactome:R-SSC-1799339|reactome:R-SSC-6791226|reactome:R-SSC-72706|reactome:R-SSC-975956|reactome:R-SSC-975957|go:"GO:0098556"(cytoplasmic side of rough endoplasmic reticulum membrane)|refseq:XP_005662419.1|refseq:XP_005674290.1	go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033897"(ribonuclease T2 activity)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044228"(host cell surface)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0070008"(serine-type exopeptidase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR042311|interpro:IPR042309|interpro:IPR042310|interpro:IPR021824|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR022120|interpro:IPR030399|interpro:IPR027417|interpro:IPR008751(Peptidase C53, pestivirus Npro)|interpro:IPR032521|interpro:IPR000280(Peptidase S31, pestivurus polyprotein NS3/p80)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR033130|interpro:IPR042542|interpro:IPR036430|rcsb pdb:5WX1|rcsb pdb:5YF5|rcsb pdb:5YF6|rcsb pdb:5YF7|rcsb pdb:5YF8|rcsb pdb:6AE4|rcsb pdb:6AE5|rcsb pdb:6AE6|rcsb pdb:6AE7|interpro:IPR043502|interpro:IPR043128	-	-	-	figure legend:table s2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2016/08/24	2016/11/30	rogid:77LFR7/2somk6blVogZf1XFdJLk9823	rogid:ztG+uovVXdRDsNER3V/Xz69PFsA11096	rigid:Fbcrpy0TOvS5VqePUp+c0NkdGzo	false	-	binding-associated region:691..691-1054..1054	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:F1SKJ2	uniprotkb:Q5U8X5	intact:EBI-12576467|ensembl:ENSSSCP00000000148	intact:EBI-12557210	psi-mi:f1skj2_pig(display_long)|uniprotkb:TXN2(gene name)|psi-mi:TXN2(display_short)	psi-mi:q5u8x5_9flav(display_long)|uniprotkb:Capsid protein C(gene name synonym)|uniprotkb:Cysteine protease NS2(gene name synonym)|uniprotkb:"E(rns) glycoprotein"(gene name synonym)|uniprotkb:Envelope glycoprotein E1(gene name synonym)|uniprotkb:Envelope glycoprotein E2(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:N-terminal protease(gene name synonym)|uniprotkb:NS5B(gene name synonym)|uniprotkb:Non-structural protein 2(gene name synonym)|uniprotkb:Non-structural protein 2-3(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Non-structural protein 5A(gene name synonym)|uniprotkb:RNA-directed RNA polymerase(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:gp33(gene name synonym)|uniprotkb:gp44/48(gene name synonym)|uniprotkb:gp55(gene name synonym)|uniprotkb:Viroporin p7(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	He et al. (2014)	pubmed:24184320|imex:IM-25910	taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)")	taxid:11096(classical swine fever virus)|taxid:11096(Classical swine fever virus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-12654506|imex:IM-25910-19	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSSSCG00000000144(gene)|ensembl:ENSSSCT00000000150(transcript)|go:"GO:0006662"(glycerol ether metabolic process)|go:"GO:0015035"(protein-disulfide reductase activity)|interpro:IPR005746(Thioredoxin)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249	go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033897"(ribonuclease T2 activity)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044228"(host cell surface)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0070008"(serine-type exopeptidase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR042311|interpro:IPR042309|interpro:IPR042310|interpro:IPR021824|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR022120|interpro:IPR030399|interpro:IPR027417|interpro:IPR008751(Peptidase C53, pestivirus Npro)|interpro:IPR032521|interpro:IPR000280(Peptidase S31, pestivurus polyprotein NS3/p80)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR033130|interpro:IPR042542|interpro:IPR036430|rcsb pdb:5WX1|rcsb pdb:5YF5|rcsb pdb:5YF6|rcsb pdb:5YF7|rcsb pdb:5YF8|rcsb pdb:6AE4|rcsb pdb:6AE5|rcsb pdb:6AE6|rcsb pdb:6AE7|interpro:IPR043502|interpro:IPR043128	-	-	-	figure legend:table s2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2016/08/24	2020/01/08	rogid:cQXQk1+IG238sMDhDj0BdZTwvDg9823	rogid:ztG+uovVXdRDsNER3V/Xz69PFsA11096	rigid:IRxth/Vc4XSGlCip1HDtSiLXaFg	false	-	binding-associated region:691..691-1054..1054	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q6QAQ1	uniprotkb:Q5U8X5	intact:EBI-12513903|ensembl:ENSSSCP00000035521|ensembl:ENSSSCP00005020052|ensembl:ENSSSCP00005020098|ensembl:ENSSSCP00030001789|ensembl:ENSSSCP00035020643|ensembl:ENSSSCP00040028298|ensembl:ENSSSCP00045032503|ensembl:ENSSSCP00050037989|ensembl:ENSSSCP00055019840|ensembl:ENSSSCP00055019871|ensembl:ENSSSCP00055019955|ensembl:ENSSSCP00060010890|ensembl:ENSSSCP00065022539|ensembl:ENSSSCP00065022540|ensembl:ENSSSCP00065022543|ensembl:ENSSSCP00070018415|ensembl:ENSSSCP00070018418	intact:EBI-12557210	psi-mi:actb_pig(display_long)|uniprotkb:Beta-actin(gene name synonym)|uniprotkb:ACTB(gene name)|psi-mi:ACTB(display_short)	psi-mi:q5u8x5_9flav(display_long)|uniprotkb:Capsid protein C(gene name synonym)|uniprotkb:Cysteine protease NS2(gene name synonym)|uniprotkb:"E(rns) glycoprotein"(gene name synonym)|uniprotkb:Envelope glycoprotein E1(gene name synonym)|uniprotkb:Envelope glycoprotein E2(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:N-terminal protease(gene name synonym)|uniprotkb:NS5B(gene name synonym)|uniprotkb:Non-structural protein 2(gene name synonym)|uniprotkb:Non-structural protein 2-3(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Non-structural protein 5A(gene name synonym)|uniprotkb:RNA-directed RNA polymerase(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:gp33(gene name synonym)|uniprotkb:gp44/48(gene name synonym)|uniprotkb:gp55(gene name synonym)|uniprotkb:Viroporin p7(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	He et al. (2014)	pubmed:24184320|imex:IM-25910	taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)")	taxid:11096(classical swine fever virus)|taxid:11096(Classical swine fever virus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-12513894|imex:IM-25910-41	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSSSCG00000007585(gene)|ensembl:ENSSSCG00005020690(gene)|ensembl:ENSSSCG00030003451(gene)|ensembl:ENSSSCG00035038792(gene)|ensembl:ENSSSCG00040049462(gene)|ensembl:ENSSSCG00045027458(gene)|ensembl:ENSSSCG00050065025(gene)|ensembl:ENSSSCG00055012597(gene)|ensembl:ENSSSCG00060019124(gene)|ensembl:ENSSSCG00065037921(gene)|ensembl:ENSSSCG00070011353(gene)|ensembl:ENSSSCT00000042531(transcript)|ensembl:ENSSSCT00005032891(transcript)|ensembl:ENSSSCT00005032974(transcript)|ensembl:ENSSSCT00030004519(transcript)|ensembl:ENSSSCT00035051497(transcript)|ensembl:ENSSSCT00040066726(transcript)|ensembl:ENSSSCT00045046823(transcript)|ensembl:ENSSSCT00050088575(transcript)|ensembl:ENSSSCT00055024985(transcript)|ensembl:ENSSSCT00055025023(transcript)|ensembl:ENSSSCT00055025117(transcript)|ensembl:ENSSSCT00060025751(transcript)|ensembl:ENSSSCT00065051863(transcript)|ensembl:ENSSSCT00065051865(transcript)|ensembl:ENSSSCT00065051872(transcript)|ensembl:ENSSSCT00070022245(transcript)|ensembl:ENSSSCT00070022248(transcript)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007409"(axonogenesis)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022898"(regulation of transmembrane transporter activity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030424"(axon)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030957"(Tat protein binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045176"(apical protein localization)|go:"GO:0045202"(synapse)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048870"(cell motility)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051621"(regulation of norepinephrine uptake)|go:"GO:0070160"(tight junction)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0072749"(cellular response to cytochalasin B)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0150111"(regulation of transepithelial transport)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|rcsb pdb:5ADX|rcsb pdb:5AFU|rcsb pdb:6F1T|rcsb pdb:6F38|rcsb pdb:6F3A|rcsb pdb:6ZNL|rcsb pdb:6ZNM|rcsb pdb:6ZNN|rcsb pdb:6ZNO|rcsb pdb:6ZO4|reactome:R-SSC-190873|reactome:R-SSC-196025|reactome:R-SSC-2029482|reactome:R-SSC-4420097|reactome:R-SSC-446353|reactome:R-SSC-5250924|reactome:R-SSC-5626467|reactome:R-SSC-5663213|reactome:R-SSC-5663220|reactome:R-SSC-5674135|reactome:R-SSC-5689603|reactome:R-SSC-8856828|reactome:R-SSC-9035034|refseq:XP_003124328.1	go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033897"(ribonuclease T2 activity)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044228"(host cell surface)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0070008"(serine-type exopeptidase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR042311|interpro:IPR042309|interpro:IPR042310|interpro:IPR021824|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR022120|interpro:IPR030399|interpro:IPR027417|interpro:IPR008751(Peptidase C53, pestivirus Npro)|interpro:IPR032521|interpro:IPR000280(Peptidase S31, pestivurus polyprotein NS3/p80)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR033130|interpro:IPR042542|interpro:IPR036430|rcsb pdb:5WX1|rcsb pdb:5YF5|rcsb pdb:5YF6|rcsb pdb:5YF7|rcsb pdb:5YF8|rcsb pdb:6AE4|rcsb pdb:6AE5|rcsb pdb:6AE6|rcsb pdb:6AE7|interpro:IPR043502|interpro:IPR043128	-	-	-	figure legend:2A|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2016/08/24	2016/10/26	rogid:Hoge1B8Pn56kvbNTpkSLsQuHwRc9823	rogid:ztG+uovVXdRDsNER3V/Xz69PFsA11096	rigid:jizNxhYKdE2czkFcmYp1LLncMFA	false	myc tag:n-n	flag tag:n-n|binding-associated region:691..691-1054..1054	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q6QAQ1	uniprotkb:Q5U8X5	intact:EBI-12513903|ensembl:ENSSSCP00000035521|ensembl:ENSSSCP00005020052|ensembl:ENSSSCP00005020098|ensembl:ENSSSCP00030001789|ensembl:ENSSSCP00035020643|ensembl:ENSSSCP00040028298|ensembl:ENSSSCP00045032503|ensembl:ENSSSCP00050037989|ensembl:ENSSSCP00055019840|ensembl:ENSSSCP00055019871|ensembl:ENSSSCP00055019955|ensembl:ENSSSCP00060010890|ensembl:ENSSSCP00065022539|ensembl:ENSSSCP00065022540|ensembl:ENSSSCP00065022543|ensembl:ENSSSCP00070018415|ensembl:ENSSSCP00070018418	intact:EBI-12557210	psi-mi:actb_pig(display_long)|uniprotkb:Beta-actin(gene name synonym)|uniprotkb:ACTB(gene name)|psi-mi:ACTB(display_short)	psi-mi:q5u8x5_9flav(display_long)|uniprotkb:Capsid protein C(gene name synonym)|uniprotkb:Cysteine protease NS2(gene name synonym)|uniprotkb:"E(rns) glycoprotein"(gene name synonym)|uniprotkb:Envelope glycoprotein E1(gene name synonym)|uniprotkb:Envelope glycoprotein E2(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:N-terminal protease(gene name synonym)|uniprotkb:NS5B(gene name synonym)|uniprotkb:Non-structural protein 2(gene name synonym)|uniprotkb:Non-structural protein 2-3(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Non-structural protein 5A(gene name synonym)|uniprotkb:RNA-directed RNA polymerase(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:gp33(gene name synonym)|uniprotkb:gp44/48(gene name synonym)|uniprotkb:gp55(gene name synonym)|uniprotkb:Viroporin p7(gene name synonym)	psi-mi:"MI:0096"(pull down)	He et al. (2014)	pubmed:24184320|imex:IM-25910	taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)")	taxid:11096(classical swine fever virus)|taxid:11096(Classical swine fever virus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-12576926|imex:IM-25910-43	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSSSCG00000007585(gene)|ensembl:ENSSSCG00005020690(gene)|ensembl:ENSSSCG00030003451(gene)|ensembl:ENSSSCG00035038792(gene)|ensembl:ENSSSCG00040049462(gene)|ensembl:ENSSSCG00045027458(gene)|ensembl:ENSSSCG00050065025(gene)|ensembl:ENSSSCG00055012597(gene)|ensembl:ENSSSCG00060019124(gene)|ensembl:ENSSSCG00065037921(gene)|ensembl:ENSSSCG00070011353(gene)|ensembl:ENSSSCT00000042531(transcript)|ensembl:ENSSSCT00005032891(transcript)|ensembl:ENSSSCT00005032974(transcript)|ensembl:ENSSSCT00030004519(transcript)|ensembl:ENSSSCT00035051497(transcript)|ensembl:ENSSSCT00040066726(transcript)|ensembl:ENSSSCT00045046823(transcript)|ensembl:ENSSSCT00050088575(transcript)|ensembl:ENSSSCT00055024985(transcript)|ensembl:ENSSSCT00055025023(transcript)|ensembl:ENSSSCT00055025117(transcript)|ensembl:ENSSSCT00060025751(transcript)|ensembl:ENSSSCT00065051863(transcript)|ensembl:ENSSSCT00065051865(transcript)|ensembl:ENSSSCT00065051872(transcript)|ensembl:ENSSSCT00070022245(transcript)|ensembl:ENSSSCT00070022248(transcript)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007409"(axonogenesis)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022898"(regulation of transmembrane transporter activity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030424"(axon)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030957"(Tat protein binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045176"(apical protein localization)|go:"GO:0045202"(synapse)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048870"(cell motility)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051621"(regulation of norepinephrine uptake)|go:"GO:0070160"(tight junction)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0072749"(cellular response to cytochalasin B)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0150111"(regulation of transepithelial transport)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|rcsb pdb:5ADX|rcsb pdb:5AFU|rcsb pdb:6F1T|rcsb pdb:6F38|rcsb pdb:6F3A|rcsb pdb:6ZNL|rcsb pdb:6ZNM|rcsb pdb:6ZNN|rcsb pdb:6ZNO|rcsb pdb:6ZO4|reactome:R-SSC-190873|reactome:R-SSC-196025|reactome:R-SSC-2029482|reactome:R-SSC-4420097|reactome:R-SSC-446353|reactome:R-SSC-5250924|reactome:R-SSC-5626467|reactome:R-SSC-5663213|reactome:R-SSC-5663220|reactome:R-SSC-5674135|reactome:R-SSC-5689603|reactome:R-SSC-8856828|reactome:R-SSC-9035034|refseq:XP_003124328.1	go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033897"(ribonuclease T2 activity)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044228"(host cell surface)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0070008"(serine-type exopeptidase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR042311|interpro:IPR042309|interpro:IPR042310|interpro:IPR021824|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR022120|interpro:IPR030399|interpro:IPR027417|interpro:IPR008751(Peptidase C53, pestivirus Npro)|interpro:IPR032521|interpro:IPR000280(Peptidase S31, pestivurus polyprotein NS3/p80)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR033130|interpro:IPR042542|interpro:IPR036430|rcsb pdb:5WX1|rcsb pdb:5YF5|rcsb pdb:5YF6|rcsb pdb:5YF7|rcsb pdb:5YF8|rcsb pdb:6AE4|rcsb pdb:6AE5|rcsb pdb:6AE6|rcsb pdb:6AE7|interpro:IPR043502|interpro:IPR043128	-	-	-	figure legend:2B & S1|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/08/24	2016/10/26	rogid:Hoge1B8Pn56kvbNTpkSLsQuHwRc9823	rogid:ztG+uovVXdRDsNER3V/Xz69PFsA11096	rigid:jizNxhYKdE2czkFcmYp1LLncMFA	false	myc tag:n-n|sufficient binding region:95-188	glutathione s tranferase tag:c-c|sufficient binding region:691..691-1054..1054	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q6QAQ1	uniprotkb:Q5U8X5	intact:EBI-12513903|ensembl:ENSSSCP00000035521|ensembl:ENSSSCP00005020052|ensembl:ENSSSCP00005020098|ensembl:ENSSSCP00030001789|ensembl:ENSSSCP00035020643|ensembl:ENSSSCP00040028298|ensembl:ENSSSCP00045032503|ensembl:ENSSSCP00050037989|ensembl:ENSSSCP00055019840|ensembl:ENSSSCP00055019871|ensembl:ENSSSCP00055019955|ensembl:ENSSSCP00060010890|ensembl:ENSSSCP00065022539|ensembl:ENSSSCP00065022540|ensembl:ENSSSCP00065022543|ensembl:ENSSSCP00070018415|ensembl:ENSSSCP00070018418	intact:EBI-12557210	psi-mi:actb_pig(display_long)|uniprotkb:Beta-actin(gene name synonym)|uniprotkb:ACTB(gene name)|psi-mi:ACTB(display_short)	psi-mi:q5u8x5_9flav(display_long)|uniprotkb:Capsid protein C(gene name synonym)|uniprotkb:Cysteine protease NS2(gene name synonym)|uniprotkb:"E(rns) glycoprotein"(gene name synonym)|uniprotkb:Envelope glycoprotein E1(gene name synonym)|uniprotkb:Envelope glycoprotein E2(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:N-terminal protease(gene name synonym)|uniprotkb:NS5B(gene name synonym)|uniprotkb:Non-structural protein 2(gene name synonym)|uniprotkb:Non-structural protein 2-3(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Non-structural protein 5A(gene name synonym)|uniprotkb:RNA-directed RNA polymerase(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:gp33(gene name synonym)|uniprotkb:gp44/48(gene name synonym)|uniprotkb:gp55(gene name synonym)|uniprotkb:Viroporin p7(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	He et al. (2014)	pubmed:24184320|imex:IM-25910	taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)")	taxid:11096(classical swine fever virus)|taxid:11096(Classical swine fever virus)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-12513963|imex:IM-25910-21	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSSSCG00000007585(gene)|ensembl:ENSSSCG00005020690(gene)|ensembl:ENSSSCG00030003451(gene)|ensembl:ENSSSCG00035038792(gene)|ensembl:ENSSSCG00040049462(gene)|ensembl:ENSSSCG00045027458(gene)|ensembl:ENSSSCG00050065025(gene)|ensembl:ENSSSCG00055012597(gene)|ensembl:ENSSSCG00060019124(gene)|ensembl:ENSSSCG00065037921(gene)|ensembl:ENSSSCG00070011353(gene)|ensembl:ENSSSCT00000042531(transcript)|ensembl:ENSSSCT00005032891(transcript)|ensembl:ENSSSCT00005032974(transcript)|ensembl:ENSSSCT00030004519(transcript)|ensembl:ENSSSCT00035051497(transcript)|ensembl:ENSSSCT00040066726(transcript)|ensembl:ENSSSCT00045046823(transcript)|ensembl:ENSSSCT00050088575(transcript)|ensembl:ENSSSCT00055024985(transcript)|ensembl:ENSSSCT00055025023(transcript)|ensembl:ENSSSCT00055025117(transcript)|ensembl:ENSSSCT00060025751(transcript)|ensembl:ENSSSCT00065051863(transcript)|ensembl:ENSSSCT00065051865(transcript)|ensembl:ENSSSCT00065051872(transcript)|ensembl:ENSSSCT00070022245(transcript)|ensembl:ENSSSCT00070022248(transcript)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007409"(axonogenesis)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022898"(regulation of transmembrane transporter activity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030424"(axon)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030957"(Tat protein binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045176"(apical protein localization)|go:"GO:0045202"(synapse)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048870"(cell motility)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051621"(regulation of norepinephrine uptake)|go:"GO:0070160"(tight junction)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0072749"(cellular response to cytochalasin B)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0150111"(regulation of transepithelial transport)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|rcsb pdb:5ADX|rcsb pdb:5AFU|rcsb pdb:6F1T|rcsb pdb:6F38|rcsb pdb:6F3A|rcsb pdb:6ZNL|rcsb pdb:6ZNM|rcsb pdb:6ZNN|rcsb pdb:6ZNO|rcsb pdb:6ZO4|reactome:R-SSC-190873|reactome:R-SSC-196025|reactome:R-SSC-2029482|reactome:R-SSC-4420097|reactome:R-SSC-446353|reactome:R-SSC-5250924|reactome:R-SSC-5626467|reactome:R-SSC-5663213|reactome:R-SSC-5663220|reactome:R-SSC-5674135|reactome:R-SSC-5689603|reactome:R-SSC-8856828|reactome:R-SSC-9035034|refseq:XP_003124328.1	go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033897"(ribonuclease T2 activity)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044228"(host cell surface)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0070008"(serine-type exopeptidase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR042311|interpro:IPR042309|interpro:IPR042310|interpro:IPR021824|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR022120|interpro:IPR030399|interpro:IPR027417|interpro:IPR008751(Peptidase C53, pestivirus Npro)|interpro:IPR032521|interpro:IPR000280(Peptidase S31, pestivurus polyprotein NS3/p80)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR033130|interpro:IPR042542|interpro:IPR036430|rcsb pdb:5WX1|rcsb pdb:5YF5|rcsb pdb:5YF6|rcsb pdb:5YF7|rcsb pdb:5YF8|rcsb pdb:6AE4|rcsb pdb:6AE5|rcsb pdb:6AE6|rcsb pdb:6AE7|interpro:IPR043502|interpro:IPR043128	go:"GO:0030430"(host cell cytoplasm)	-	-	figure legend:2C|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2016/08/24	2016/10/26	rogid:Hoge1B8Pn56kvbNTpkSLsQuHwRc9823	rogid:ztG+uovVXdRDsNER3V/Xz69PFsA11096	rigid:jizNxhYKdE2czkFcmYp1LLncMFA	false	myc tag:n-n	flag tag:n-n|binding-associated region:691..691-1054..1054	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:Q6QAQ1	uniprotkb:Q5U8X5	intact:EBI-12513903|ensembl:ENSSSCP00000035521|ensembl:ENSSSCP00005020052|ensembl:ENSSSCP00005020098|ensembl:ENSSSCP00030001789|ensembl:ENSSSCP00035020643|ensembl:ENSSSCP00040028298|ensembl:ENSSSCP00045032503|ensembl:ENSSSCP00050037989|ensembl:ENSSSCP00055019840|ensembl:ENSSSCP00055019871|ensembl:ENSSSCP00055019955|ensembl:ENSSSCP00060010890|ensembl:ENSSSCP00065022539|ensembl:ENSSSCP00065022540|ensembl:ENSSSCP00065022543|ensembl:ENSSSCP00070018415|ensembl:ENSSSCP00070018418	intact:EBI-12557210	psi-mi:actb_pig(display_long)|uniprotkb:Beta-actin(gene name synonym)|uniprotkb:ACTB(gene name)|psi-mi:ACTB(display_short)	psi-mi:q5u8x5_9flav(display_long)|uniprotkb:Capsid protein C(gene name synonym)|uniprotkb:Cysteine protease NS2(gene name synonym)|uniprotkb:"E(rns) glycoprotein"(gene name synonym)|uniprotkb:Envelope glycoprotein E1(gene name synonym)|uniprotkb:Envelope glycoprotein E2(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:N-terminal protease(gene name synonym)|uniprotkb:NS5B(gene name synonym)|uniprotkb:Non-structural protein 2(gene name synonym)|uniprotkb:Non-structural protein 2-3(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Non-structural protein 5A(gene name synonym)|uniprotkb:RNA-directed RNA polymerase(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:gp33(gene name synonym)|uniprotkb:gp44/48(gene name synonym)|uniprotkb:gp55(gene name synonym)|uniprotkb:Viroporin p7(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	He et al. (2014)	pubmed:24184320|imex:IM-25910	taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)")	taxid:11096(classical swine fever virus)|taxid:11096(Classical swine fever virus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-12576890|imex:IM-25910-23	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSSSCG00000007585(gene)|ensembl:ENSSSCG00005020690(gene)|ensembl:ENSSSCG00030003451(gene)|ensembl:ENSSSCG00035038792(gene)|ensembl:ENSSSCG00040049462(gene)|ensembl:ENSSSCG00045027458(gene)|ensembl:ENSSSCG00050065025(gene)|ensembl:ENSSSCG00055012597(gene)|ensembl:ENSSSCG00060019124(gene)|ensembl:ENSSSCG00065037921(gene)|ensembl:ENSSSCG00070011353(gene)|ensembl:ENSSSCT00000042531(transcript)|ensembl:ENSSSCT00005032891(transcript)|ensembl:ENSSSCT00005032974(transcript)|ensembl:ENSSSCT00030004519(transcript)|ensembl:ENSSSCT00035051497(transcript)|ensembl:ENSSSCT00040066726(transcript)|ensembl:ENSSSCT00045046823(transcript)|ensembl:ENSSSCT00050088575(transcript)|ensembl:ENSSSCT00055024985(transcript)|ensembl:ENSSSCT00055025023(transcript)|ensembl:ENSSSCT00055025117(transcript)|ensembl:ENSSSCT00060025751(transcript)|ensembl:ENSSSCT00065051863(transcript)|ensembl:ENSSSCT00065051865(transcript)|ensembl:ENSSSCT00065051872(transcript)|ensembl:ENSSSCT00070022245(transcript)|ensembl:ENSSSCT00070022248(transcript)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007409"(axonogenesis)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022898"(regulation of transmembrane transporter activity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030424"(axon)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030957"(Tat protein binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045176"(apical protein localization)|go:"GO:0045202"(synapse)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048870"(cell motility)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051621"(regulation of norepinephrine uptake)|go:"GO:0070160"(tight junction)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0072749"(cellular response to cytochalasin B)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0150111"(regulation of transepithelial transport)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|rcsb pdb:5ADX|rcsb pdb:5AFU|rcsb pdb:6F1T|rcsb pdb:6F38|rcsb pdb:6F3A|rcsb pdb:6ZNL|rcsb pdb:6ZNM|rcsb pdb:6ZNN|rcsb pdb:6ZNO|rcsb pdb:6ZO4|reactome:R-SSC-190873|reactome:R-SSC-196025|reactome:R-SSC-2029482|reactome:R-SSC-4420097|reactome:R-SSC-446353|reactome:R-SSC-5250924|reactome:R-SSC-5626467|reactome:R-SSC-5663213|reactome:R-SSC-5663220|reactome:R-SSC-5674135|reactome:R-SSC-5689603|reactome:R-SSC-8856828|reactome:R-SSC-9035034|refseq:XP_003124328.1	go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033897"(ribonuclease T2 activity)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044228"(host cell surface)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0070008"(serine-type exopeptidase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR042311|interpro:IPR042309|interpro:IPR042310|interpro:IPR021824|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR022120|interpro:IPR030399|interpro:IPR027417|interpro:IPR008751(Peptidase C53, pestivirus Npro)|interpro:IPR032521|interpro:IPR000280(Peptidase S31, pestivurus polyprotein NS3/p80)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR033130|interpro:IPR042542|interpro:IPR036430|rcsb pdb:5WX1|rcsb pdb:5YF5|rcsb pdb:5YF6|rcsb pdb:5YF7|rcsb pdb:5YF8|rcsb pdb:6AE4|rcsb pdb:6AE5|rcsb pdb:6AE6|rcsb pdb:6AE7|interpro:IPR043502|interpro:IPR043128	-	-	-	figure legend:1, 3B & 3D|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2016/08/24	2016/10/26	rogid:Hoge1B8Pn56kvbNTpkSLsQuHwRc9823	rogid:ztG+uovVXdRDsNER3V/Xz69PFsA11096	rigid:jizNxhYKdE2czkFcmYp1LLncMFA	false	sufficient binding region:95-188	sufficient binding region:691..691-1054..1054	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q6QAQ1	uniprotkb:Q5U8X5	intact:EBI-12513903|ensembl:ENSSSCP00000035521|ensembl:ENSSSCP00005020052|ensembl:ENSSSCP00005020098|ensembl:ENSSSCP00030001789|ensembl:ENSSSCP00035020643|ensembl:ENSSSCP00040028298|ensembl:ENSSSCP00045032503|ensembl:ENSSSCP00050037989|ensembl:ENSSSCP00055019840|ensembl:ENSSSCP00055019871|ensembl:ENSSSCP00055019955|ensembl:ENSSSCP00060010890|ensembl:ENSSSCP00065022539|ensembl:ENSSSCP00065022540|ensembl:ENSSSCP00065022543|ensembl:ENSSSCP00070018415|ensembl:ENSSSCP00070018418	intact:EBI-12557210	psi-mi:actb_pig(display_long)|uniprotkb:Beta-actin(gene name synonym)|uniprotkb:ACTB(gene name)|psi-mi:ACTB(display_short)	psi-mi:q5u8x5_9flav(display_long)|uniprotkb:Capsid protein C(gene name synonym)|uniprotkb:Cysteine protease NS2(gene name synonym)|uniprotkb:"E(rns) glycoprotein"(gene name synonym)|uniprotkb:Envelope glycoprotein E1(gene name synonym)|uniprotkb:Envelope glycoprotein E2(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:N-terminal protease(gene name synonym)|uniprotkb:NS5B(gene name synonym)|uniprotkb:Non-structural protein 2(gene name synonym)|uniprotkb:Non-structural protein 2-3(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Non-structural protein 5A(gene name synonym)|uniprotkb:RNA-directed RNA polymerase(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:gp33(gene name synonym)|uniprotkb:gp44/48(gene name synonym)|uniprotkb:gp55(gene name synonym)|uniprotkb:Viroporin p7(gene name synonym)	psi-mi:"MI:0809"(bimolecular fluorescence complementation)	He et al. (2014)	pubmed:24184320|imex:IM-25910	taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)")	taxid:11096(classical swine fever virus)|taxid:11096(Classical swine fever virus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-12576870|imex:IM-25910-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSSSCG00000007585(gene)|ensembl:ENSSSCG00005020690(gene)|ensembl:ENSSSCG00030003451(gene)|ensembl:ENSSSCG00035038792(gene)|ensembl:ENSSSCG00040049462(gene)|ensembl:ENSSSCG00045027458(gene)|ensembl:ENSSSCG00050065025(gene)|ensembl:ENSSSCG00055012597(gene)|ensembl:ENSSSCG00060019124(gene)|ensembl:ENSSSCG00065037921(gene)|ensembl:ENSSSCG00070011353(gene)|ensembl:ENSSSCT00000042531(transcript)|ensembl:ENSSSCT00005032891(transcript)|ensembl:ENSSSCT00005032974(transcript)|ensembl:ENSSSCT00030004519(transcript)|ensembl:ENSSSCT00035051497(transcript)|ensembl:ENSSSCT00040066726(transcript)|ensembl:ENSSSCT00045046823(transcript)|ensembl:ENSSSCT00050088575(transcript)|ensembl:ENSSSCT00055024985(transcript)|ensembl:ENSSSCT00055025023(transcript)|ensembl:ENSSSCT00055025117(transcript)|ensembl:ENSSSCT00060025751(transcript)|ensembl:ENSSSCT00065051863(transcript)|ensembl:ENSSSCT00065051865(transcript)|ensembl:ENSSSCT00065051872(transcript)|ensembl:ENSSSCT00070022245(transcript)|ensembl:ENSSSCT00070022248(transcript)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007409"(axonogenesis)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022898"(regulation of transmembrane transporter activity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030424"(axon)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030957"(Tat protein binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045176"(apical protein localization)|go:"GO:0045202"(synapse)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048870"(cell motility)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051621"(regulation of norepinephrine uptake)|go:"GO:0070160"(tight junction)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0072749"(cellular response to cytochalasin B)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0150111"(regulation of transepithelial transport)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|rcsb pdb:5ADX|rcsb pdb:5AFU|rcsb pdb:6F1T|rcsb pdb:6F38|rcsb pdb:6F3A|rcsb pdb:6ZNL|rcsb pdb:6ZNM|rcsb pdb:6ZNN|rcsb pdb:6ZNO|rcsb pdb:6ZO4|reactome:R-SSC-190873|reactome:R-SSC-196025|reactome:R-SSC-2029482|reactome:R-SSC-4420097|reactome:R-SSC-446353|reactome:R-SSC-5250924|reactome:R-SSC-5626467|reactome:R-SSC-5663213|reactome:R-SSC-5663220|reactome:R-SSC-5674135|reactome:R-SSC-5689603|reactome:R-SSC-8856828|reactome:R-SSC-9035034|refseq:XP_003124328.1	go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033897"(ribonuclease T2 activity)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044228"(host cell surface)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0070008"(serine-type exopeptidase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR042311|interpro:IPR042309|interpro:IPR042310|interpro:IPR021824|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR022120|interpro:IPR030399|interpro:IPR027417|interpro:IPR008751(Peptidase C53, pestivirus Npro)|interpro:IPR032521|interpro:IPR000280(Peptidase S31, pestivurus polyprotein NS3/p80)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR033130|interpro:IPR042542|interpro:IPR036430|rcsb pdb:5WX1|rcsb pdb:5YF5|rcsb pdb:5YF6|rcsb pdb:5YF7|rcsb pdb:5YF8|rcsb pdb:6AE4|rcsb pdb:6AE5|rcsb pdb:6AE6|rcsb pdb:6AE7|interpro:IPR043502|interpro:IPR043128	-	-	-	figure legend:2D|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2016/08/24	2016/10/26	rogid:Hoge1B8Pn56kvbNTpkSLsQuHwRc9823	rogid:ztG+uovVXdRDsNER3V/Xz69PFsA11096	rigid:jizNxhYKdE2czkFcmYp1LLncMFA	false	ceYFP:?-?	neYFP:?-?	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)