#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q20937 uniprotkb:Q9U1P4 intact:EBI-12507059|intact:EBI-25615781|uniprotkb:A0A1D3PCL8|uniprotkb:A0A1D3PCL9|uniprotkb:A0A1D3PCM5|uniprotkb:S5ZDJ9|ensemblmetazoa:F57B9.2a.1 intact:EBI-12507045|ensemblmetazoa:ZC518.3b.1 psi-mi:cnot1_caeel(display_long)|uniprotkb:let-711(gene name)|psi-mi:let-711(display_short)|uniprotkb:ntl-1(gene name synonym)|uniprotkb:CCR4-associated factor let-711(gene name synonym)|uniprotkb:Lethal protein 711(gene name synonym)|uniprotkb:Negative regulator of transcription subunit 1 homolog(gene name synonym)|uniprotkb:spn-3(gene name synonym)|uniprotkb:F57B9.2(orf name) psi-mi:q9u1p4_caeel(display_long)|uniprotkb:ccr-4(gene name)|psi-mi:ccr-4(display_short)|uniprotkb:CELE_ZC518.3(orf name)|uniprotkb:ZC518.3(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Nousch et al. (2013) imex:IM-25489|pubmed:23843623 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12508979|imex:IM-25489-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:F57B9.2b|wormbase:F57B9.2c|wormbase:F57B9.2d|wormbase:F57B9.2e|ensemblmetazoa:F57B9.2a.1(transcript)|ensemblmetazoa:WBGene00002845(gene)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0002119"(nematode larval development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0048477"(oogenesis)|go:"GO:0060090"(molecular adaptor activity)|refseq:NP_498516.3|interpro:IPR007196(CCR4-Not complex component, Not1)|interpro:IPR024557|interpro:IPR032191|interpro:IPR032194|interpro:IPR032193|interpro:IPR016021(MIF4-like, type 1/2/3)|wormbase:F57B9.2a|interpro:IPR038535|interpro:IPR040398 ensemblmetazoa:WBGene00000376(gene)|ensemblmetazoa:ZC518.3b.1(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0046872"(metal ion binding)|refseq:NP_001023607.1|wormbase:ZC518.3b|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR032675|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR036691 - - - figure legend:Fig. 4A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) - 2016/08/18 2016/08/18 rogid:vCMGbp52aQW5m6YV1AyH19C3xgw6239 rogid:UryG47s16OG65a14oK2shcl+4sY6239 rigid:TRv1SV7hJP4PEo7nEUm2lTfVGck false lap tag:c-c - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q20937 uniprotkb:Q17345 intact:EBI-12507059|intact:EBI-25615781|uniprotkb:A0A1D3PCL8|uniprotkb:A0A1D3PCL9|uniprotkb:A0A1D3PCM5|uniprotkb:S5ZDJ9|ensemblmetazoa:F57B9.2a.1 intact:EBI-331358|ensemblmetazoa:Y56A3A.20.1 psi-mi:cnot1_caeel(display_long)|uniprotkb:let-711(gene name)|psi-mi:let-711(display_short)|uniprotkb:ntl-1(gene name synonym)|uniprotkb:CCR4-associated factor let-711(gene name synonym)|uniprotkb:Lethal protein 711(gene name synonym)|uniprotkb:Negative regulator of transcription subunit 1 homolog(gene name synonym)|uniprotkb:spn-3(gene name synonym)|uniprotkb:F57B9.2(orf name) psi-mi:cnot7_caeel(display_long)|uniprotkb:Y56A3A.20(orf name)|uniprotkb:ccf-1(gene name)|psi-mi:ccf-1(display_short)|uniprotkb:CCR4-associated factor 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Nousch et al. (2013) imex:IM-25489|pubmed:23843623 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12508979|imex:IM-25489-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:F57B9.2b|wormbase:F57B9.2c|wormbase:F57B9.2d|wormbase:F57B9.2e|ensemblmetazoa:F57B9.2a.1(transcript)|ensemblmetazoa:WBGene00002845(gene)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0002119"(nematode larval development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0048477"(oogenesis)|go:"GO:0060090"(molecular adaptor activity)|refseq:NP_498516.3|interpro:IPR007196(CCR4-Not complex component, Not1)|interpro:IPR024557|interpro:IPR032191|interpro:IPR032194|interpro:IPR032193|interpro:IPR016021(MIF4-like, type 1/2/3)|wormbase:F57B9.2a|interpro:IPR038535|interpro:IPR040398 refseq:NP_499553.1|wormbase:Y56A3A.20|dip:DIP-29083N|ensemblmetazoa:WBGene00000369(gene)|ensemblmetazoa:Y56A3A.20.1(transcript)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0043186"(P granule)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0046872"(metal ion binding)|go:"GO:0048477"(oogenesis)|interpro:IPR006941(Ribonuclease CAF1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036397|interpro:IPR039637|go:"GO:0030015"(CCR4-NOT core complex) - - - figure legend:Fig. 4A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) - 2016/08/18 2016/08/18 rogid:vCMGbp52aQW5m6YV1AyH19C3xgw6239 rogid:sAQ34vRYj8W+D4ifvJAcA+rBwH46239 rigid:TRv1SV7hJP4PEo7nEUm2lTfVGck false lap tag:c-c - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q17345 uniprotkb:Q9U1P4 intact:EBI-331358|ensemblmetazoa:Y56A3A.20.1 intact:EBI-12507045|ensemblmetazoa:ZC518.3b.1 psi-mi:cnot7_caeel(display_long)|uniprotkb:Y56A3A.20(orf name)|uniprotkb:ccf-1(gene name)|psi-mi:ccf-1(display_short)|uniprotkb:CCR4-associated factor 1(gene name synonym) psi-mi:q9u1p4_caeel(display_long)|uniprotkb:ccr-4(gene name)|psi-mi:ccr-4(display_short)|uniprotkb:CELE_ZC518.3(orf name)|uniprotkb:ZC518.3(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Nousch et al. (2013) imex:IM-25489|pubmed:23843623 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12509042|imex:IM-25489-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_499553.1|wormbase:Y56A3A.20|dip:DIP-29083N|ensemblmetazoa:WBGene00000369(gene)|ensemblmetazoa:Y56A3A.20.1(transcript)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0043186"(P granule)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0046872"(metal ion binding)|go:"GO:0048477"(oogenesis)|interpro:IPR006941(Ribonuclease CAF1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036397|interpro:IPR039637|go:"GO:0030015"(CCR4-NOT core complex) ensemblmetazoa:WBGene00000376(gene)|ensemblmetazoa:ZC518.3b.1(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0046872"(metal ion binding)|refseq:NP_001023607.1|wormbase:ZC518.3b|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR032675|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR036691 - - - figure legend:Fig. 4B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) - 2016/08/18 2016/08/18 rogid:sAQ34vRYj8W+D4ifvJAcA+rBwH46239 rogid:UryG47s16OG65a14oK2shcl+4sY6239 rigid:TRv1SV7hJP4PEo7nEUm2lTfVGck false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q17345 uniprotkb:Q20937 intact:EBI-331358|ensemblmetazoa:Y56A3A.20.1 intact:EBI-12507059|intact:EBI-25615781|uniprotkb:A0A1D3PCL8|uniprotkb:A0A1D3PCL9|uniprotkb:A0A1D3PCM5|uniprotkb:S5ZDJ9|ensemblmetazoa:F57B9.2a.1 psi-mi:cnot7_caeel(display_long)|uniprotkb:Y56A3A.20(orf name)|uniprotkb:ccf-1(gene name)|psi-mi:ccf-1(display_short)|uniprotkb:CCR4-associated factor 1(gene name synonym) psi-mi:cnot1_caeel(display_long)|uniprotkb:let-711(gene name)|psi-mi:let-711(display_short)|uniprotkb:ntl-1(gene name synonym)|uniprotkb:CCR4-associated factor let-711(gene name synonym)|uniprotkb:Lethal protein 711(gene name synonym)|uniprotkb:Negative regulator of transcription subunit 1 homolog(gene name synonym)|uniprotkb:spn-3(gene name synonym)|uniprotkb:F57B9.2(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Nousch et al. (2013) imex:IM-25489|pubmed:23843623 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12509042|imex:IM-25489-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_499553.1|wormbase:Y56A3A.20|dip:DIP-29083N|ensemblmetazoa:WBGene00000369(gene)|ensemblmetazoa:Y56A3A.20.1(transcript)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0043186"(P granule)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0046872"(metal ion binding)|go:"GO:0048477"(oogenesis)|interpro:IPR006941(Ribonuclease CAF1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036397|interpro:IPR039637|go:"GO:0030015"(CCR4-NOT core complex) wormbase:F57B9.2b|wormbase:F57B9.2c|wormbase:F57B9.2d|wormbase:F57B9.2e|ensemblmetazoa:F57B9.2a.1(transcript)|ensemblmetazoa:WBGene00002845(gene)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0002119"(nematode larval development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0048477"(oogenesis)|go:"GO:0060090"(molecular adaptor activity)|refseq:NP_498516.3|interpro:IPR007196(CCR4-Not complex component, Not1)|interpro:IPR024557|interpro:IPR032191|interpro:IPR032194|interpro:IPR032193|interpro:IPR016021(MIF4-like, type 1/2/3)|wormbase:F57B9.2a|interpro:IPR038535|interpro:IPR040398 - - - figure legend:Fig. 4B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) - 2016/08/18 2016/08/18 rogid:sAQ34vRYj8W+D4ifvJAcA+rBwH46239 rogid:vCMGbp52aQW5m6YV1AyH19C3xgw6239 rigid:TRv1SV7hJP4PEo7nEUm2lTfVGck false - lap tag:c-c - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)