#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q5U8X5	uniprotkb:F1SBL0	intact:EBI-12557210	intact:EBI-12596795|ensembl:ENSSSCP00000007521	psi-mi:q5u8x5_9flav(display_long)|uniprotkb:Capsid protein C(gene name synonym)|uniprotkb:Cysteine protease NS2(gene name synonym)|uniprotkb:"E(rns) glycoprotein"(gene name synonym)|uniprotkb:Envelope glycoprotein E1(gene name synonym)|uniprotkb:Envelope glycoprotein E2(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:N-terminal protease(gene name synonym)|uniprotkb:NS5B(gene name synonym)|uniprotkb:Non-structural protein 2(gene name synonym)|uniprotkb:Non-structural protein 2-3(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Non-structural protein 5A(gene name synonym)|uniprotkb:RNA-directed RNA polymerase(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:gp33(gene name synonym)|uniprotkb:gp44/48(gene name synonym)|uniprotkb:gp55(gene name synonym)|uniprotkb:Viroporin p7(gene name synonym)	psi-mi:f1sbl0_pig(display_long)|uniprotkb:PLCB4(gene name)|psi-mi:PLCB4(display_short)	psi-mi:"MI:0096"(pull down)	Li et al. (2013)	pubmed:23487454|imex:IM-26069	taxid:11096(classical swine fever virus)|taxid:11096(Classical swine fever virus)	taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-12557194|imex:IM-26069-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033897"(ribonuclease T2 activity)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044228"(host cell surface)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0070008"(serine-type exopeptidase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR042311|interpro:IPR042309|interpro:IPR042310|interpro:IPR021824|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR022120|interpro:IPR030399|interpro:IPR027417|interpro:IPR008751(Peptidase C53, pestivirus Npro)|interpro:IPR032521|interpro:IPR000280(Peptidase S31, pestivurus polyprotein NS3/p80)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR033130|interpro:IPR042542|interpro:IPR036430|rcsb pdb:5WX1|rcsb pdb:5YF5|rcsb pdb:5YF6|rcsb pdb:5YF7|rcsb pdb:5YF8|rcsb pdb:6AE4|rcsb pdb:6AE5|rcsb pdb:6AE6|rcsb pdb:6AE7|interpro:IPR043502|interpro:IPR043128	ensembl:ENSSSCG00000007058(gene)|ensembl:ENSSSCT00000007729(transcript)|go:"GO:0004435"(phosphatidylinositol phospholipase C activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0035556"(intracellular signal transduction)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000909(Phospholipase C, phosphatidylinositol-specific , X region)|interpro:IPR001192("Phospholipase C, phosphoinositol-specific, C-terminal (PLC)")|interpro:IPR001711(Phospholipase C, phosphatidylinositol-specific, Y domain)|interpro:IPR009535(Protein of unknown function DUF1154)|interpro:IPR011992(EF-Hand type)|interpro:IPR015359(Phospholipase C, phosphoinositol-specific, EF-hand-like)|interpro:IPR016280(Phosphatidylinositol-4, 5-bisphosphate phosphodiesterase beta)|interpro:IPR017946|interpro:IPR035892|interpro:IPR037862|interpro:IPR042531|refseq:XP_013840520.1	-	-	-	figure legend:1A and table 2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/10/07	2017/12/04	rogid:ztG+uovVXdRDsNER3V/Xz69PFsA11096	rogid:UVpzvCxyflbCXsMv/RcIQpLvz7Y9823	rigid:lTy9ZGFUu4uMV/GSUqdBaJSY/lM	false	binding-associated region:169..169-267..267|glutathione s tranferase tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q5U8X5	uniprotkb:P04246	intact:EBI-12557210	intact:EBI-12557196	psi-mi:q5u8x5_9flav(display_long)|uniprotkb:Capsid protein C(gene name synonym)|uniprotkb:Cysteine protease NS2(gene name synonym)|uniprotkb:"E(rns) glycoprotein"(gene name synonym)|uniprotkb:Envelope glycoprotein E1(gene name synonym)|uniprotkb:Envelope glycoprotein E2(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:N-terminal protease(gene name synonym)|uniprotkb:NS5B(gene name synonym)|uniprotkb:Non-structural protein 2(gene name synonym)|uniprotkb:Non-structural protein 2-3(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Non-structural protein 5A(gene name synonym)|uniprotkb:RNA-directed RNA polymerase(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:gp33(gene name synonym)|uniprotkb:gp44/48(gene name synonym)|uniprotkb:gp55(gene name synonym)|uniprotkb:Viroporin p7(gene name synonym)	psi-mi:hbt_pig(display_long)|uniprotkb:Hemoglobin theta chain(gene name synonym)|uniprotkb:Theta-globin(gene name synonym)	psi-mi:"MI:0096"(pull down)	Li et al. (2013)	pubmed:23487454|imex:IM-26069	taxid:11096(classical swine fever virus)|taxid:11096(Classical swine fever virus)	taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-12557194|imex:IM-26069-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033897"(ribonuclease T2 activity)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044228"(host cell surface)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0070008"(serine-type exopeptidase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR042311|interpro:IPR042309|interpro:IPR042310|interpro:IPR021824|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR022120|interpro:IPR030399|interpro:IPR027417|interpro:IPR008751(Peptidase C53, pestivirus Npro)|interpro:IPR032521|interpro:IPR000280(Peptidase S31, pestivurus polyprotein NS3/p80)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR033130|interpro:IPR042542|interpro:IPR036430|rcsb pdb:5WX1|rcsb pdb:5YF5|rcsb pdb:5YF6|rcsb pdb:5YF7|rcsb pdb:5YF8|rcsb pdb:6AE4|rcsb pdb:6AE5|rcsb pdb:6AE6|rcsb pdb:6AE7|interpro:IPR043502|interpro:IPR043128	interpro:IPR012292(Globin)|go:"GO:0005344"(oxygen carrier activity)|go:"GO:0005833"(hemoglobin complex)|go:"GO:0019825"(oxygen binding)|go:"GO:0020037"(heme binding)|go:"GO:0031721"(hemoglobin alpha binding)|go:"GO:0031838"(haptoglobin-hemoglobin complex)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0043177"(organic acid binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0098869"(cellular oxidant detoxification)|interpro:IPR000971(Globin, subset)|interpro:IPR009050(Globin-like)|interpro:IPR002337(Haemoglobin, beta)	-	-	-	figure legend:1A and table 2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/10/07	2017/12/04	rogid:ztG+uovVXdRDsNER3V/Xz69PFsA11096	rogid:okN/Xbh6YPvrVjqtIMJeRi1Yrgo9823	rigid:lTy9ZGFUu4uMV/GSUqdBaJSY/lM	false	binding-associated region:169..169-267..267|glutathione s tranferase tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q5U8X5	uniprotkb:P02067	intact:EBI-12557210	intact:EBI-9014782|uniprotkb:Q29025	psi-mi:q5u8x5_9flav(display_long)|uniprotkb:Capsid protein C(gene name synonym)|uniprotkb:Cysteine protease NS2(gene name synonym)|uniprotkb:"E(rns) glycoprotein"(gene name synonym)|uniprotkb:Envelope glycoprotein E1(gene name synonym)|uniprotkb:Envelope glycoprotein E2(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:N-terminal protease(gene name synonym)|uniprotkb:NS5B(gene name synonym)|uniprotkb:Non-structural protein 2(gene name synonym)|uniprotkb:Non-structural protein 2-3(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Non-structural protein 5A(gene name synonym)|uniprotkb:RNA-directed RNA polymerase(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:gp33(gene name synonym)|uniprotkb:gp44/48(gene name synonym)|uniprotkb:gp55(gene name synonym)|uniprotkb:Viroporin p7(gene name synonym)	psi-mi:hbb_pig(display_long)|uniprotkb:HBB(gene name)|psi-mi:HBB(display_short)|uniprotkb:Beta-globin(gene name synonym)|uniprotkb:Hemoglobin beta chain(gene name synonym)	psi-mi:"MI:0096"(pull down)	Li et al. (2013)	pubmed:23487454|imex:IM-26069	taxid:11096(classical swine fever virus)|taxid:11096(Classical swine fever virus)	taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-12557194|imex:IM-26069-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033897"(ribonuclease T2 activity)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044228"(host cell surface)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0070008"(serine-type exopeptidase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR042311|interpro:IPR042309|interpro:IPR042310|interpro:IPR021824|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR022120|interpro:IPR030399|interpro:IPR027417|interpro:IPR008751(Peptidase C53, pestivirus Npro)|interpro:IPR032521|interpro:IPR000280(Peptidase S31, pestivurus polyprotein NS3/p80)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR033130|interpro:IPR042542|interpro:IPR036430|rcsb pdb:5WX1|rcsb pdb:5YF5|rcsb pdb:5YF6|rcsb pdb:5YF7|rcsb pdb:5YF8|rcsb pdb:6AE4|rcsb pdb:6AE5|rcsb pdb:6AE6|rcsb pdb:6AE7|interpro:IPR043502|interpro:IPR043128	rcsb pdb:4F4O|go:"GO:0005344"(oxygen carrier activity)|go:"GO:0005833"(hemoglobin complex)|go:"GO:0019825"(oxygen binding)|go:"GO:0020037"(heme binding)|go:"GO:0031721"(hemoglobin alpha binding)|go:"GO:0031838"(haptoglobin-hemoglobin complex)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0043177"(organic acid binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0098869"(cellular oxidant detoxification)|interpro:IPR000971(Globin, subset)|interpro:IPR002337(Haemoglobin, beta)|interpro:IPR009050(Globin-like)|interpro:IPR012292(Globin)|rcsb pdb:1QPW|rcsb pdb:2PGH|refseq:NP_001138313.1|dip:DIP-59910N	-	-	-	figure legend:1A and table 2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/10/07	2017/12/04	rogid:ztG+uovVXdRDsNER3V/Xz69PFsA11096	rogid:+WrDid52VQTowTAejke46OcI2I49823	rigid:lTy9ZGFUu4uMV/GSUqdBaJSY/lM	false	binding-associated region:169..169-267..267|glutathione s tranferase tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q5U8X5	uniprotkb:P02067	intact:EBI-12557210	intact:EBI-9014782|uniprotkb:Q29025	psi-mi:q5u8x5_9flav(display_long)|uniprotkb:Capsid protein C(gene name synonym)|uniprotkb:Cysteine protease NS2(gene name synonym)|uniprotkb:"E(rns) glycoprotein"(gene name synonym)|uniprotkb:Envelope glycoprotein E1(gene name synonym)|uniprotkb:Envelope glycoprotein E2(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:N-terminal protease(gene name synonym)|uniprotkb:NS5B(gene name synonym)|uniprotkb:Non-structural protein 2(gene name synonym)|uniprotkb:Non-structural protein 2-3(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Non-structural protein 5A(gene name synonym)|uniprotkb:RNA-directed RNA polymerase(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:gp33(gene name synonym)|uniprotkb:gp44/48(gene name synonym)|uniprotkb:gp55(gene name synonym)|uniprotkb:Viroporin p7(gene name synonym)	psi-mi:hbb_pig(display_long)|uniprotkb:HBB(gene name)|psi-mi:HBB(display_short)|uniprotkb:Beta-globin(gene name synonym)|uniprotkb:Hemoglobin beta chain(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Li et al. (2013)	pubmed:23487454|imex:IM-26069	taxid:11096(classical swine fever virus)|taxid:11096(Classical swine fever virus)	taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-12557272|imex:IM-26069-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033897"(ribonuclease T2 activity)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044228"(host cell surface)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0070008"(serine-type exopeptidase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR042311|interpro:IPR042309|interpro:IPR042310|interpro:IPR021824|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR022120|interpro:IPR030399|interpro:IPR027417|interpro:IPR008751(Peptidase C53, pestivirus Npro)|interpro:IPR032521|interpro:IPR000280(Peptidase S31, pestivurus polyprotein NS3/p80)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR033130|interpro:IPR042542|interpro:IPR036430|rcsb pdb:5WX1|rcsb pdb:5YF5|rcsb pdb:5YF6|rcsb pdb:5YF7|rcsb pdb:5YF8|rcsb pdb:6AE4|rcsb pdb:6AE5|rcsb pdb:6AE6|rcsb pdb:6AE7|interpro:IPR043502|interpro:IPR043128	rcsb pdb:4F4O|go:"GO:0005344"(oxygen carrier activity)|go:"GO:0005833"(hemoglobin complex)|go:"GO:0019825"(oxygen binding)|go:"GO:0020037"(heme binding)|go:"GO:0031721"(hemoglobin alpha binding)|go:"GO:0031838"(haptoglobin-hemoglobin complex)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0043177"(organic acid binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0098869"(cellular oxidant detoxification)|interpro:IPR000971(Globin, subset)|interpro:IPR002337(Haemoglobin, beta)|interpro:IPR009050(Globin-like)|interpro:IPR012292(Globin)|rcsb pdb:1QPW|rcsb pdb:2PGH|refseq:NP_001138313.1|dip:DIP-59910N	-	-	-	figure legend:2A and 3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2016/10/07	2016/10/26	rogid:ztG+uovVXdRDsNER3V/Xz69PFsA11096	rogid:+WrDid52VQTowTAejke46OcI2I49823	rigid:gWtoTdDIwR+crb16W0/JRrhNhWY	false	myc tag:?-?|binding-associated region:169..169-267..267	flag tag:n-n|necessary binding region:100-146	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9GLV6	uniprotkb:Q5U8X5	intact:EBI-12557374	intact:EBI-12557210	psi-mi:ddx58_pig(display_long)|uniprotkb:DDX58(gene name)|psi-mi:DDX58(display_short)|uniprotkb:DEAD box protein 58(gene name synonym)|uniprotkb:RHIV-1(gene name synonym)|uniprotkb:RIG-I-like receptor 1(gene name synonym)|uniprotkb:RNA helicase induced by virus(gene name synonym)|uniprotkb:Retinoic acid-inducible gene 1 protein(gene name synonym)|uniprotkb:Retinoic acid-inducible gene I protein(gene name synonym)|uniprotkb:Probable ATP-dependent RNA helicase DDX58(gene name synonym)	psi-mi:q5u8x5_9flav(display_long)|uniprotkb:Capsid protein C(gene name synonym)|uniprotkb:Cysteine protease NS2(gene name synonym)|uniprotkb:"E(rns) glycoprotein"(gene name synonym)|uniprotkb:Envelope glycoprotein E1(gene name synonym)|uniprotkb:Envelope glycoprotein E2(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:N-terminal protease(gene name synonym)|uniprotkb:NS5B(gene name synonym)|uniprotkb:Non-structural protein 2(gene name synonym)|uniprotkb:Non-structural protein 2-3(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Non-structural protein 5A(gene name synonym)|uniprotkb:RNA-directed RNA polymerase(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:gp33(gene name synonym)|uniprotkb:gp44/48(gene name synonym)|uniprotkb:gp55(gene name synonym)|uniprotkb:Viroporin p7(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Li et al. (2013)	pubmed:23487454|imex:IM-26069	taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)")	taxid:11096(classical swine fever virus)|taxid:11096(Classical swine fever virus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-12557362|imex:IM-26069-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR011029(DEATH-like)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0002735"(positive regulation of myeloid dendritic cell cytokine production)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009615"(response to virus)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0039529"(RIG-I signaling pathway)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0045087"(innate immune response)|go:"GO:0060760"(positive regulation of response to cytokine stimulus)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0140374"(antiviral innate immune response)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:0005524"(ATP binding)|interpro:IPR041204|interpro:IPR042145|interpro:IPR031964|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR027417|interpro:IPR021673|interpro:IPR038557	go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033897"(ribonuclease T2 activity)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044228"(host cell surface)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0070008"(serine-type exopeptidase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR042311|interpro:IPR042309|interpro:IPR042310|interpro:IPR021824|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR022120|interpro:IPR030399|interpro:IPR027417|interpro:IPR008751(Peptidase C53, pestivirus Npro)|interpro:IPR032521|interpro:IPR000280(Peptidase S31, pestivurus polyprotein NS3/p80)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR033130|interpro:IPR042542|interpro:IPR036430|rcsb pdb:5WX1|rcsb pdb:5YF5|rcsb pdb:5YF6|rcsb pdb:5YF7|rcsb pdb:5YF8|rcsb pdb:6AE4|rcsb pdb:6AE5|rcsb pdb:6AE6|rcsb pdb:6AE7|interpro:IPR043502|interpro:IPR043128	-	-	-	figure legend:8A|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2016/10/07	2016/10/26	rogid:n3+ZCQm85bpLi8XYOBHHdQWyUgk9823	rogid:ztG+uovVXdRDsNER3V/Xz69PFsA11096	rigid:1j5++XAQM3CELp1XwwlpJgZ+41A	false	myc tag:?-?	binding-associated region:169..169-267..267|flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q5U8X5	uniprotkb:P02067	intact:EBI-12557210	intact:EBI-9014782|uniprotkb:Q29025	psi-mi:q5u8x5_9flav(display_long)|uniprotkb:Capsid protein C(gene name synonym)|uniprotkb:Cysteine protease NS2(gene name synonym)|uniprotkb:"E(rns) glycoprotein"(gene name synonym)|uniprotkb:Envelope glycoprotein E1(gene name synonym)|uniprotkb:Envelope glycoprotein E2(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:N-terminal protease(gene name synonym)|uniprotkb:NS5B(gene name synonym)|uniprotkb:Non-structural protein 2(gene name synonym)|uniprotkb:Non-structural protein 2-3(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Non-structural protein 5A(gene name synonym)|uniprotkb:RNA-directed RNA polymerase(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:gp33(gene name synonym)|uniprotkb:gp44/48(gene name synonym)|uniprotkb:gp55(gene name synonym)|uniprotkb:Viroporin p7(gene name synonym)	psi-mi:hbb_pig(display_long)|uniprotkb:HBB(gene name)|psi-mi:HBB(display_short)|uniprotkb:Beta-globin(gene name synonym)|uniprotkb:Hemoglobin beta chain(gene name synonym)	psi-mi:"MI:0096"(pull down)	Li et al. (2013)	pubmed:23487454|imex:IM-26069	taxid:11096(classical swine fever virus)|taxid:11096(Classical swine fever virus)	taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-12557291|imex:IM-26069-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033897"(ribonuclease T2 activity)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044228"(host cell surface)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0070008"(serine-type exopeptidase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR042311|interpro:IPR042309|interpro:IPR042310|interpro:IPR021824|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR022120|interpro:IPR030399|interpro:IPR027417|interpro:IPR008751(Peptidase C53, pestivirus Npro)|interpro:IPR032521|interpro:IPR000280(Peptidase S31, pestivurus polyprotein NS3/p80)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR033130|interpro:IPR042542|interpro:IPR036430|rcsb pdb:5WX1|rcsb pdb:5YF5|rcsb pdb:5YF6|rcsb pdb:5YF7|rcsb pdb:5YF8|rcsb pdb:6AE4|rcsb pdb:6AE5|rcsb pdb:6AE6|rcsb pdb:6AE7|interpro:IPR043502|interpro:IPR043128	rcsb pdb:4F4O|go:"GO:0005344"(oxygen carrier activity)|go:"GO:0005833"(hemoglobin complex)|go:"GO:0019825"(oxygen binding)|go:"GO:0020037"(heme binding)|go:"GO:0031721"(hemoglobin alpha binding)|go:"GO:0031838"(haptoglobin-hemoglobin complex)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0043177"(organic acid binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0098869"(cellular oxidant detoxification)|interpro:IPR000971(Globin, subset)|interpro:IPR002337(Haemoglobin, beta)|interpro:IPR009050(Globin-like)|interpro:IPR012292(Globin)|rcsb pdb:1QPW|rcsb pdb:2PGH|refseq:NP_001138313.1|dip:DIP-59910N	-	-	-	figure legend:2B|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/10/07	2016/10/26	rogid:ztG+uovVXdRDsNER3V/Xz69PFsA11096	rogid:+WrDid52VQTowTAejke46OcI2I49823	rigid:gWtoTdDIwR+crb16W0/JRrhNhWY	false	glutathione s tranferase tag:n-n|binding-associated region:169..169-267..267	flag tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q5U8X5	uniprotkb:P02067	intact:EBI-12557210	intact:EBI-9014782|uniprotkb:Q29025	psi-mi:q5u8x5_9flav(display_long)|uniprotkb:Capsid protein C(gene name synonym)|uniprotkb:Cysteine protease NS2(gene name synonym)|uniprotkb:"E(rns) glycoprotein"(gene name synonym)|uniprotkb:Envelope glycoprotein E1(gene name synonym)|uniprotkb:Envelope glycoprotein E2(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:N-terminal protease(gene name synonym)|uniprotkb:NS5B(gene name synonym)|uniprotkb:Non-structural protein 2(gene name synonym)|uniprotkb:Non-structural protein 2-3(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Non-structural protein 5A(gene name synonym)|uniprotkb:RNA-directed RNA polymerase(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:gp33(gene name synonym)|uniprotkb:gp44/48(gene name synonym)|uniprotkb:gp55(gene name synonym)|uniprotkb:Viroporin p7(gene name synonym)	psi-mi:hbb_pig(display_long)|uniprotkb:HBB(gene name)|psi-mi:HBB(display_short)|uniprotkb:Beta-globin(gene name synonym)|uniprotkb:Hemoglobin beta chain(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Li et al. (2013)	pubmed:23487454|imex:IM-26069	taxid:11096(classical swine fever virus)|taxid:11096(Classical swine fever virus)	taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-12557311|imex:IM-26069-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033897"(ribonuclease T2 activity)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044228"(host cell surface)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0070008"(serine-type exopeptidase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR042311|interpro:IPR042309|interpro:IPR042310|interpro:IPR021824|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR022120|interpro:IPR030399|interpro:IPR027417|interpro:IPR008751(Peptidase C53, pestivirus Npro)|interpro:IPR032521|interpro:IPR000280(Peptidase S31, pestivurus polyprotein NS3/p80)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR033130|interpro:IPR042542|interpro:IPR036430|rcsb pdb:5WX1|rcsb pdb:5YF5|rcsb pdb:5YF6|rcsb pdb:5YF7|rcsb pdb:5YF8|rcsb pdb:6AE4|rcsb pdb:6AE5|rcsb pdb:6AE6|rcsb pdb:6AE7|interpro:IPR043502|interpro:IPR043128	rcsb pdb:4F4O|go:"GO:0005344"(oxygen carrier activity)|go:"GO:0005833"(hemoglobin complex)|go:"GO:0019825"(oxygen binding)|go:"GO:0020037"(heme binding)|go:"GO:0031721"(hemoglobin alpha binding)|go:"GO:0031838"(haptoglobin-hemoglobin complex)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0043177"(organic acid binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0098869"(cellular oxidant detoxification)|interpro:IPR000971(Globin, subset)|interpro:IPR002337(Haemoglobin, beta)|interpro:IPR009050(Globin-like)|interpro:IPR012292(Globin)|rcsb pdb:1QPW|rcsb pdb:2PGH|refseq:NP_001138313.1|dip:DIP-59910N	-	-	-	figure legend:2C|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9823(pig-pk15)|taxid:9823(pig pk15)	-	2016/10/07	2016/10/10	rogid:ztG+uovVXdRDsNER3V/Xz69PFsA11096	rogid:+WrDid52VQTowTAejke46OcI2I49823	rigid:gWtoTdDIwR+crb16W0/JRrhNhWY	false	binding-associated region:169..169-267..267	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q5U8X5	uniprotkb:P02067	intact:EBI-12557210	intact:EBI-9014782|uniprotkb:Q29025	psi-mi:q5u8x5_9flav(display_long)|uniprotkb:Capsid protein C(gene name synonym)|uniprotkb:Cysteine protease NS2(gene name synonym)|uniprotkb:"E(rns) glycoprotein"(gene name synonym)|uniprotkb:Envelope glycoprotein E1(gene name synonym)|uniprotkb:Envelope glycoprotein E2(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:N-terminal protease(gene name synonym)|uniprotkb:NS5B(gene name synonym)|uniprotkb:Non-structural protein 2(gene name synonym)|uniprotkb:Non-structural protein 2-3(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Non-structural protein 5A(gene name synonym)|uniprotkb:RNA-directed RNA polymerase(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:gp33(gene name synonym)|uniprotkb:gp44/48(gene name synonym)|uniprotkb:gp55(gene name synonym)|uniprotkb:Viroporin p7(gene name synonym)	psi-mi:hbb_pig(display_long)|uniprotkb:HBB(gene name)|psi-mi:HBB(display_short)|uniprotkb:Beta-globin(gene name synonym)|uniprotkb:Hemoglobin beta chain(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Li et al. (2013)	pubmed:23487454|imex:IM-26069	taxid:11096(classical swine fever virus)|taxid:11096(Classical swine fever virus)	taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)")	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-12557329|imex:IM-26069-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033897"(ribonuclease T2 activity)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044228"(host cell surface)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0070008"(serine-type exopeptidase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR042311|interpro:IPR042309|interpro:IPR042310|interpro:IPR021824|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR022120|interpro:IPR030399|interpro:IPR027417|interpro:IPR008751(Peptidase C53, pestivirus Npro)|interpro:IPR032521|interpro:IPR000280(Peptidase S31, pestivurus polyprotein NS3/p80)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR033130|interpro:IPR042542|interpro:IPR036430|rcsb pdb:5WX1|rcsb pdb:5YF5|rcsb pdb:5YF6|rcsb pdb:5YF7|rcsb pdb:5YF8|rcsb pdb:6AE4|rcsb pdb:6AE5|rcsb pdb:6AE6|rcsb pdb:6AE7|interpro:IPR043502|interpro:IPR043128	rcsb pdb:4F4O|go:"GO:0005344"(oxygen carrier activity)|go:"GO:0005833"(hemoglobin complex)|go:"GO:0019825"(oxygen binding)|go:"GO:0020037"(heme binding)|go:"GO:0031721"(hemoglobin alpha binding)|go:"GO:0031838"(haptoglobin-hemoglobin complex)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0043177"(organic acid binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0098869"(cellular oxidant detoxification)|interpro:IPR000971(Globin, subset)|interpro:IPR002337(Haemoglobin, beta)|interpro:IPR009050(Globin-like)|interpro:IPR012292(Globin)|rcsb pdb:1QPW|rcsb pdb:2PGH|refseq:NP_001138313.1|dip:DIP-59910N	go:"GO:0030430"(host cell cytoplasm)	-	-	figure legend:2D|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2016/10/07	2016/10/11	rogid:ztG+uovVXdRDsNER3V/Xz69PFsA11096	rogid:+WrDid52VQTowTAejke46OcI2I49823	rigid:gWtoTdDIwR+crb16W0/JRrhNhWY	false	myc tag:?-?|binding-associated region:169..169-267..267	flag tag:n-n	-	-	psi-mi:"MI:1200"(immunocytochemistry)	psi-mi:"MI:1200"(immunocytochemistry)
uniprotkb:Q5U8X5	uniprotkb:P02067	intact:EBI-12557210	intact:EBI-9014782|uniprotkb:Q29025	psi-mi:q5u8x5_9flav(display_long)|uniprotkb:Capsid protein C(gene name synonym)|uniprotkb:Cysteine protease NS2(gene name synonym)|uniprotkb:"E(rns) glycoprotein"(gene name synonym)|uniprotkb:Envelope glycoprotein E1(gene name synonym)|uniprotkb:Envelope glycoprotein E2(gene name synonym)|uniprotkb:Genome polyprotein(gene name synonym)|uniprotkb:N-terminal protease(gene name synonym)|uniprotkb:NS5B(gene name synonym)|uniprotkb:Non-structural protein 2(gene name synonym)|uniprotkb:Non-structural protein 2-3(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4A(gene name synonym)|uniprotkb:Non-structural protein 4B(gene name synonym)|uniprotkb:Non-structural protein 5A(gene name synonym)|uniprotkb:RNA-directed RNA polymerase(gene name synonym)|uniprotkb:Serine protease NS3(gene name synonym)|uniprotkb:gp33(gene name synonym)|uniprotkb:gp44/48(gene name synonym)|uniprotkb:gp55(gene name synonym)|uniprotkb:Viroporin p7(gene name synonym)	psi-mi:hbb_pig(display_long)|uniprotkb:HBB(gene name)|psi-mi:HBB(display_short)|uniprotkb:Beta-globin(gene name synonym)|uniprotkb:Hemoglobin beta chain(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Li et al. (2013)	pubmed:23487454|imex:IM-26069	taxid:11096(classical swine fever virus)|taxid:11096(Classical swine fever virus)	taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)")	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-12557350|imex:IM-26069-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019082"(viral protein processing)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033897"(ribonuclease T2 activity)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044228"(host cell surface)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0070008"(serine-type exopeptidase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR042311|interpro:IPR042309|interpro:IPR042310|interpro:IPR021824|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR022120|interpro:IPR030399|interpro:IPR027417|interpro:IPR008751(Peptidase C53, pestivirus Npro)|interpro:IPR032521|interpro:IPR000280(Peptidase S31, pestivurus polyprotein NS3/p80)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR033130|interpro:IPR042542|interpro:IPR036430|rcsb pdb:5WX1|rcsb pdb:5YF5|rcsb pdb:5YF6|rcsb pdb:5YF7|rcsb pdb:5YF8|rcsb pdb:6AE4|rcsb pdb:6AE5|rcsb pdb:6AE6|rcsb pdb:6AE7|interpro:IPR043502|interpro:IPR043128	rcsb pdb:4F4O|go:"GO:0005344"(oxygen carrier activity)|go:"GO:0005833"(hemoglobin complex)|go:"GO:0019825"(oxygen binding)|go:"GO:0020037"(heme binding)|go:"GO:0031721"(hemoglobin alpha binding)|go:"GO:0031838"(haptoglobin-hemoglobin complex)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0043177"(organic acid binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0098869"(cellular oxidant detoxification)|interpro:IPR000971(Globin, subset)|interpro:IPR002337(Haemoglobin, beta)|interpro:IPR009050(Globin-like)|interpro:IPR012292(Globin)|rcsb pdb:1QPW|rcsb pdb:2PGH|refseq:NP_001138313.1|dip:DIP-59910N	go:"GO:0030430"(host cell cytoplasm)	-	-	figure legend:2E|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9823(pig-pk15)|taxid:9823(pig pk15)	-	2016/10/07	2016/10/11	rogid:ztG+uovVXdRDsNER3V/Xz69PFsA11096	rogid:+WrDid52VQTowTAejke46OcI2I49823	rigid:gWtoTdDIwR+crb16W0/JRrhNhWY	false	binding-associated region:169..169-267..267	-	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)