#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O75717 uniprotkb:P51530 intact:EBI-3951691|ensembl:ENSP00000353793|uniprotkb:C9JW18|uniprotkb:F6W0U7 intact:EBI-6677369|ensembl:ENSP00000351185|uniprotkb:Q2NKM1|uniprotkb:Q5TC49|uniprotkb:Q5TC50|uniprotkb:Q6P455|uniprotkb:Q6PI80|uniprotkb:Q7Z6H9|uniprotkb:Q8N346 psi-mi:wdhd1_human(display_long)|uniprotkb:WDHD1(gene name)|psi-mi:WDHD1(display_short)|uniprotkb:AND1(gene name synonym)|uniprotkb:Acidic nucleoplasmic DNA-binding protein 1(gene name synonym) psi-mi:dna2_human(display_long)|uniprotkb:DNA2(gene name)|psi-mi:DNA2(display_short)|uniprotkb:DNA2L(gene name synonym)|uniprotkb:KIAA0083(gene name synonym)|uniprotkb:DNA replication ATP-dependent helicase-like homolog(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Duxin et al. (2012) imex:IM-25097|pubmed:22570476 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-11686285|imex:IM-25097-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000198554(gene)|ensembl:ENST00000360586(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0043596"(nuclear replication fork)|interpro:IPR001680(WD40 repeat)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR022100|interpro:IPR024977|interpro:IPR036322|interpro:IPR036910|rcsb pdb:2D7L|rcsb pdb:5GVA|rcsb pdb:5GVB|rcsb pdb:5OGS|rcsb pdb:6XTY|refseq:NP_001008397.1|refseq:NP_009017.1 ensembl:ENSG00000138346(gene)|ensembl:ENST00000358410(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0004518"(nuclease activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006260"(DNA replication)|go:"GO:0006264"(mitochondrial DNA replication)|go:"GO:0006284"(base-excision repair)|go:"GO:0016890"(site-specific endodeoxyribonuclease activity, specific for altered base)|go:"GO:0017108"(5'-flap endonuclease activity)|go:"GO:0017116"(single-stranded DNA helicase activity)|go:"GO:0032201"(telomere maintenance via semi-conservative replication)|go:"GO:0033567"(DNA replication, Okazaki fragment processing)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043137"(DNA replication, removal of RNA primer)|go:"GO:0043139"(5'-3' DNA helicase activity)|go:"GO:0043504"(mitochondrial DNA repair)|go:"GO:0044806"(G-quadruplex DNA unwinding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0071932"(replication fork reversal)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|go:"GO:0090656"(t-circle formation)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902990"(mitotic telomere maintenance via semi-conservative replication)|interpro:IPR014808(DNA replication factor Dna2)|interpro:IPR026851|interpro:IPR027417|interpro:IPR041677|interpro:IPR041679|rcsb pdb:5EAY|reactome:R-HSA-174437|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69166|reactome:R-HSA-69473|refseq:NP_001073918.2 - - - figure legend:3A|comment:The interaction is seen in asynchronous cells and synchronous cells at the G1/S border, but not in cells arrested in G0/G1.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2016/03/08 2016/04/11 rogid:SNbJutgOfo9kguAoOv5Hdhk5s+k9606 rogid:ftL7EgRB3WfppiSav6gChBIOMZs9606 rigid:sgTfFR2aedahOHE/BOVEeXmu664 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)