#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9UHP7-1	uniprotkb:Q12918	intact:EBI-13640978|ensembl:ENSP00000290855	intact:EBI-2805465|uniprotkb:Q24K24|ensembl:ENSP00000229402	psi-mi:q9uhp7-1(display_long)|uniprotkb:CLEC2D(gene name)|psi-mi:CLEC2D(display_short)|uniprotkb:CLAX(gene name synonym)|uniprotkb:LLT1(gene name synonym)|uniprotkb:OCIL(gene name synonym)|uniprotkb:Lectin-like NK cell receptor(gene name synonym)|uniprotkb:Lectin-like transcript 1(gene name synonym)|uniprotkb:Osteoclast inhibitory lectin(gene name synonym)	psi-mi:klrb1_human(display_long)|uniprotkb:CLEC5B(gene name synonym)|uniprotkb:NKRP1A(gene name synonym)|uniprotkb:C-type lectin domain family 5 member B(gene name synonym)|uniprotkb:HNKR-P1a(gene name synonym)|uniprotkb:Natural killer cell surface protein P1A(gene name synonym)|uniprotkb:KLRB1(gene name)|psi-mi:KLRB1(display_short)	psi-mi:"MI:0107"(surface plasmon resonance)	Kamishikiryo et al. (2011)	pubmed:21572041|imex:IM-25657	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13640974|imex:IM-25657-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000069493(gene)|ensembl:ENST00000290855(transcript)|intact:EBI-16578656(isoform-parent)	ensembl:ENSG00000111796(gene)|ensembl:ENST00000229402(transcript)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030246"(carbohydrate binding)|interpro:IPR001304(C-type lectin)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR033992|rcsb pdb:5MGR|rcsb pdb:5MGS|rcsb pdb:5MGT|reactome:R-HSA-198933|refseq:NP_002249.1	-	-	-	figure legend:1B-D, 3B, Supp fig 2.|comment:"Thermodynamic Parameter for H176C mutant:  Delta G (Free energy) =   -6kcal/mol"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:53.0x10^-6(molar)	2016/12/20	2017/02/20	rogid:NLmVR/7HyMEburgQrcREMmTUPUc9606	rogid:x6/pmu6Ty9fgVeNWFgk8bBYjvxc9606	rigid:2LFaFiSom1xxrta4Oy1ZQLLokK0	false	mutation:176-176|sufficient binding region:71-191|mutation:163-163|mutation disrupting interaction strength:169-169|mutation disrupting interaction strength:175-175|mutation disrupting interaction strength:180-180|mutation disrupting interaction strength:181-181|mutation decreasing interaction strength:165-165|mutation decreasing interaction strength:167-167	biotin tag:?-?|mutation decreasing interaction strength:185-185|mutation decreasing interaction strength:186-186|mutation disrupting interaction strength:198-198|mutation with no effect:200-200|mutation disrupting interaction strength:200-200|mutation disrupting interaction strength:201-201|mutation decreasing interaction strength:205-205|sufficient binding region:90-225|mutation decreasing interaction strength:162-162|mutation with no effect:179-179|mutation decreasing interaction strength:179-179|mutation decreasing interaction strength:181-181|mutation decreasing interaction strength:183-183|mutation with no effect:185-185	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q12918	uniprotkb:Q9UHP7-1	intact:EBI-2805465|uniprotkb:Q24K24|ensembl:ENSP00000229402	intact:EBI-13640978|ensembl:ENSP00000290855	psi-mi:klrb1_human(display_long)|uniprotkb:CLEC5B(gene name synonym)|uniprotkb:NKRP1A(gene name synonym)|uniprotkb:C-type lectin domain family 5 member B(gene name synonym)|uniprotkb:HNKR-P1a(gene name synonym)|uniprotkb:Natural killer cell surface protein P1A(gene name synonym)|uniprotkb:KLRB1(gene name)|psi-mi:KLRB1(display_short)	psi-mi:q9uhp7-1(display_long)|uniprotkb:CLEC2D(gene name)|psi-mi:CLEC2D(display_short)|uniprotkb:CLAX(gene name synonym)|uniprotkb:LLT1(gene name synonym)|uniprotkb:OCIL(gene name synonym)|uniprotkb:Lectin-like NK cell receptor(gene name synonym)|uniprotkb:Lectin-like transcript 1(gene name synonym)|uniprotkb:Osteoclast inhibitory lectin(gene name synonym)	psi-mi:"MI:0107"(surface plasmon resonance)	Kamishikiryo et al. (2011)	pubmed:21572041|imex:IM-25657	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13641072|imex:IM-25657-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000111796(gene)|ensembl:ENST00000229402(transcript)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030246"(carbohydrate binding)|interpro:IPR001304(C-type lectin)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR033992|rcsb pdb:5MGR|rcsb pdb:5MGS|rcsb pdb:5MGT|reactome:R-HSA-198933|refseq:NP_002249.1	ensembl:ENSG00000069493(gene)|ensembl:ENST00000290855(transcript)|intact:EBI-16578656(isoform-parent)	-	-	-	figure legend:Figure 4A,  Table 2|comment:Almost all of the LLT1 mutants were unable to bind to the CD161 mutants.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:26.0x10^-6(molar)	2016/12/20	2017/02/20	rogid:x6/pmu6Ty9fgVeNWFgk8bBYjvxc9606	rogid:NLmVR/7HyMEburgQrcREMmTUPUc9606	rigid:2LFaFiSom1xxrta4Oy1ZQLLokK0	false	sufficient binding region:90-225|biotin tag:?-?|mutation increasing interaction strength:205-205	sufficient binding region:71-191|mutation increasing interaction strength:169-169	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)