#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9GMD3 uniprotkb:A7YWF3 intact:EBI-11784379 intact:EBI-11784441|ensembl:ENSBTAP00000010098 psi-mi:q9gmd3_bovin(display_long)|uniprotkb:RPGR(gene name)|psi-mi:RPGR(display_short) psi-mi:a7ywf3_bovin(display_long)|uniprotkb:NPHP1(gene name)|psi-mi:NPHP1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Murga-Zamalloa et al. (2009) imex:IM-25422|pubmed:20664800 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-11784438|imex:IM-25422-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005794"(Golgi apparatus)|go:"GO:0007601"(visual perception) refseq:NP_001098802.1|ensembl:ENSBTAG00000007675(gene)|ensembl:ENSBTAT00000010098(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005929"(cilium)|go:"GO:0031514"(motile cilium)|go:"GO:0090251"(protein localization involved in establishment of planar polarity)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR030642|interpro:IPR036028|interpro:IPR039687 - - - figure legend:1A and 2A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9913(bovin-retina)|taxid:9913(Bovine retina) - 2016/06/21 2019/04/15 rogid:53ux/NBpvTwMoOm8RRwgiqgRoqI9913 rogid:6Un2TN0XZEE20xRNW0VgSE88hoM9913 rigid:3ub3QB6ABqvXnC6UWJR+EKTBuGE false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9GMD3 uniprotkb:E1BJB5 intact:EBI-11784379 intact:EBI-11784354|ensembl:ENSBTAP00000042828|intact:EBI-12498969 psi-mi:q9gmd3_bovin(display_long)|uniprotkb:RPGR(gene name)|psi-mi:RPGR(display_short) psi-mi:e1bjb5_bovin(display_long)|uniprotkb:NPHP4(gene name)|psi-mi:NPHP4(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Murga-Zamalloa et al. (2009) imex:IM-25422|pubmed:20664800 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-11784438|imex:IM-25422-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005794"(Golgi apparatus)|go:"GO:0007601"(visual perception) ensembl:ENSBTAG00000008126(gene)|ensembl:ENSBTAT00000045440(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775 - - - figure legend:1A and 2A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9913(bovin-retina)|taxid:9913(Bovine retina) - 2016/06/21 2019/04/15 rogid:53ux/NBpvTwMoOm8RRwgiqgRoqI9913 rogid:8vqJ2Q28pTxpvFXtK52eEdAupNc9913 rigid:3ub3QB6ABqvXnC6UWJR+EKTBuGE false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:A7YWF3 uniprotkb:Q9GMD3 intact:EBI-11784441|ensembl:ENSBTAP00000010098 intact:EBI-11784379 psi-mi:a7ywf3_bovin(display_long)|uniprotkb:NPHP1(gene name)|psi-mi:NPHP1(display_short) psi-mi:q9gmd3_bovin(display_long)|uniprotkb:RPGR(gene name)|psi-mi:RPGR(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Murga-Zamalloa et al. (2009) imex:IM-25422|pubmed:20664800 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-11784455|imex:IM-25422-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001098802.1|ensembl:ENSBTAG00000007675(gene)|ensembl:ENSBTAT00000010098(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005929"(cilium)|go:"GO:0031514"(motile cilium)|go:"GO:0090251"(protein localization involved in establishment of planar polarity)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR030642|interpro:IPR036028|interpro:IPR039687 go:"GO:0005794"(Golgi apparatus)|go:"GO:0007601"(visual perception) - - - figure legend:2B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9913(bovin-retina)|taxid:9913(Bovine retina) - 2016/06/21 2016/06/21 rogid:6Un2TN0XZEE20xRNW0VgSE88hoM9913 rogid:53ux/NBpvTwMoOm8RRwgiqgRoqI9913 rigid:v5FHfWrczzo/0efxR9aWoprj9gA false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9GMD3 uniprotkb:Q29RS3 intact:EBI-11784379 intact:EBI-11784505|ensembl:ENSBTAP00000017379 psi-mi:q9gmd3_bovin(display_long)|uniprotkb:RPGR(gene name)|psi-mi:RPGR(display_short) psi-mi:q29rs3_bovin(display_long)|uniprotkb:IQCB1(gene name)|psi-mi:IQCB1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Murga-Zamalloa et al. (2009) imex:IM-25422|pubmed:20664800 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-11784487|imex:IM-25422-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005794"(Golgi apparatus)|go:"GO:0007601"(visual perception) refseq:NP_001039846.1|refseq:XP_010799478.1|ensembl:ENSBTAG00000013069(gene)|ensembl:ENSBTAT00000017379(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0019899"(enzyme binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR027417|interpro:IPR028765 - - - figure legend:3C|comment:Detected in precipitate of NPHP4-depleted supernatant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9913(bovin-retina)|taxid:9913(Bovine retina) - 2016/06/21 2016/06/21 rogid:53ux/NBpvTwMoOm8RRwgiqgRoqI9913 rogid:40KWq2IIZyibymimA0aEKSnu9l89913 rigid:k1wWqc4YbAP4x97Nn25zfHlq4JA false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9GMD3 uniprotkb:A0JN59 intact:EBI-11784379 intact:EBI-11784492 psi-mi:q9gmd3_bovin(display_long)|uniprotkb:RPGR(gene name)|psi-mi:RPGR(display_short) psi-mi:a0jn59_bovin(display_long)|uniprotkb:INVS(gene name)|psi-mi:INVS(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Murga-Zamalloa et al. (2009) imex:IM-25422|pubmed:20664800 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-11784487|imex:IM-25422-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005794"(Golgi apparatus)|go:"GO:0007601"(visual perception) refseq:NP_001071451.1|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR036770 - - - figure legend:3C|comment:Detected in precipitate of NPHP4-depleted supernatant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9913(bovin-retina)|taxid:9913(Bovine retina) - 2016/06/21 2016/06/21 rogid:53ux/NBpvTwMoOm8RRwgiqgRoqI9913 rogid:tlZwVUFEP/AR7aNB87tTD6do+eU9913 rigid:k1wWqc4YbAP4x97Nn25zfHlq4JA false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9GMD3 uniprotkb:A7YWF3 intact:EBI-11784379 intact:EBI-11784441|ensembl:ENSBTAP00000010098 psi-mi:q9gmd3_bovin(display_long)|uniprotkb:RPGR(gene name)|psi-mi:RPGR(display_short) psi-mi:a7ywf3_bovin(display_long)|uniprotkb:NPHP1(gene name)|psi-mi:NPHP1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Murga-Zamalloa et al. (2009) imex:IM-25422|pubmed:20664800 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-11784487|imex:IM-25422-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005794"(Golgi apparatus)|go:"GO:0007601"(visual perception) refseq:NP_001098802.1|ensembl:ENSBTAG00000007675(gene)|ensembl:ENSBTAT00000010098(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005929"(cilium)|go:"GO:0031514"(motile cilium)|go:"GO:0090251"(protein localization involved in establishment of planar polarity)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR030642|interpro:IPR036028|interpro:IPR039687 - - - figure legend:3C|comment:Detected in precipitate of NPHP4-depleted supernatant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9913(bovin-retina)|taxid:9913(Bovine retina) - 2016/06/21 2016/06/21 rogid:53ux/NBpvTwMoOm8RRwgiqgRoqI9913 rogid:6Un2TN0XZEE20xRNW0VgSE88hoM9913 rigid:k1wWqc4YbAP4x97Nn25zfHlq4JA false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9GMD3 uniprotkb:E1BJB4 intact:EBI-11784379 intact:EBI-11784555|ensembl:ENSBTAP00000016585|ensembl:ENSBTAP00000062284 psi-mi:q9gmd3_bovin(display_long)|uniprotkb:RPGR(gene name)|psi-mi:RPGR(display_short) psi-mi:e1bjb4_bovin(display_long)|uniprotkb:RPGRIP1L(gene name)|psi-mi:RPGRIP1L(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Murga-Zamalloa et al. (2009) imex:IM-25422|pubmed:20664800 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-11784531|imex:IM-25422-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005794"(Golgi apparatus)|go:"GO:0007601"(visual perception) refseq:XP_002694827.3|refseq:XP_596855.6|ensembl:ENSBTAG00000012499(gene)|ensembl:ENSBTAT00000016585(transcript)|ensembl:ENSBTAT00000079027(transcript)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0060039"(pericardium development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|go:"GO:0001701"(in utero embryonic development) - - - figure legend:4B|comment:Detected in precipitate of NPHP1-depleted supernatant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9913(bovin-retina)|taxid:9913(Bovine retina) - 2016/06/21 2019/04/15 rogid:53ux/NBpvTwMoOm8RRwgiqgRoqI9913 rogid:2RsTyFlz5bdZlsigUgV/eUG3geY9913 rigid:YGQpFq2FyZ9N/Na2xD8SG4MmGIo false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9GMD3 uniprotkb:Q9TU23 intact:EBI-11784379 intact:EBI-11784535|uniprotkb:Q0P567 psi-mi:q9gmd3_bovin(display_long)|uniprotkb:RPGR(gene name)|psi-mi:RPGR(display_short) psi-mi:ce290_bovin(display_long)|uniprotkb:CEP290(gene name)|psi-mi:CEP290(display_short)|uniprotkb:NPHP6(gene name synonym)|uniprotkb:Nephrocystin-6(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Murga-Zamalloa et al. (2009) imex:IM-25422|pubmed:20664800 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-11784531|imex:IM-25422-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005794"(Golgi apparatus)|go:"GO:0007601"(visual perception) refseq:NP_777147.1|interpro:IPR032321|interpro:IPR026201|go:"GO:0001822"(kidney development)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0015031"(protein transport)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036038"(MKS complex)|go:"GO:0043010"(camera-type eye development)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0097711"(ciliary basal body-plasma membrane docking)|go:"GO:1905349"(ciliary transition zone assembly)|go:"GO:1905515"(non-motile cilium assembly) - - - figure legend:4B|comment:Detected in precipitate of NPHP1-depleted supernatant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9913(bovin-retina)|taxid:9913(Bovine retina) - 2016/06/21 2019/04/15 rogid:53ux/NBpvTwMoOm8RRwgiqgRoqI9913 rogid:ZLqclAW07oqiJv1MLNsjx3n9+Mc9913 rigid:YGQpFq2FyZ9N/Na2xD8SG4MmGIo false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9GMD3 uniprotkb:E1BJB5 intact:EBI-11784379 intact:EBI-11784354|ensembl:ENSBTAP00000042828|intact:EBI-12498969 psi-mi:q9gmd3_bovin(display_long)|uniprotkb:RPGR(gene name)|psi-mi:RPGR(display_short) psi-mi:e1bjb5_bovin(display_long)|uniprotkb:NPHP4(gene name)|psi-mi:NPHP4(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Murga-Zamalloa et al. (2009) imex:IM-25422|pubmed:20664800 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-11784531|imex:IM-25422-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005794"(Golgi apparatus)|go:"GO:0007601"(visual perception) ensembl:ENSBTAG00000008126(gene)|ensembl:ENSBTAT00000045440(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775 - - - figure legend:4B|comment:Detected in precipitate of NPHP1-depleted supernatant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9913(bovin-retina)|taxid:9913(Bovine retina) - 2016/06/21 2019/04/15 rogid:53ux/NBpvTwMoOm8RRwgiqgRoqI9913 rogid:8vqJ2Q28pTxpvFXtK52eEdAupNc9913 rigid:YGQpFq2FyZ9N/Na2xD8SG4MmGIo false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:A7YWF3 uniprotkb:E1BJB5 intact:EBI-11784441|ensembl:ENSBTAP00000010098 intact:EBI-11784354|ensembl:ENSBTAP00000042828|intact:EBI-12498969 psi-mi:a7ywf3_bovin(display_long)|uniprotkb:NPHP1(gene name)|psi-mi:NPHP1(display_short) psi-mi:e1bjb5_bovin(display_long)|uniprotkb:NPHP4(gene name)|psi-mi:NPHP4(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Murga-Zamalloa et al. (2009) imex:IM-25422|pubmed:20664800 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-11784599|imex:IM-25422-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001098802.1|ensembl:ENSBTAG00000007675(gene)|ensembl:ENSBTAT00000010098(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005929"(cilium)|go:"GO:0031514"(motile cilium)|go:"GO:0090251"(protein localization involved in establishment of planar polarity)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR030642|interpro:IPR036028|interpro:IPR039687 ensembl:ENSBTAG00000008126(gene)|ensembl:ENSBTAT00000045440(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775 - - comment:Detected in precipitate of RPGR-depleted supernatant figure legend:5B|comment:Detected in precipitate of RPGR-depleted supernatant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9913(bovin-retina)|taxid:9913(Bovine retina) - 2016/06/21 2019/04/15 rogid:6Un2TN0XZEE20xRNW0VgSE88hoM9913 rogid:8vqJ2Q28pTxpvFXtK52eEdAupNc9913 rigid:YR46BORdIE4DLclBMznQQdEMcfs false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:A7YWF3 uniprotkb:E1BJB5 intact:EBI-11784441|ensembl:ENSBTAP00000010098 intact:EBI-11784354|ensembl:ENSBTAP00000042828|intact:EBI-12498969 psi-mi:a7ywf3_bovin(display_long)|uniprotkb:NPHP1(gene name)|psi-mi:NPHP1(display_short) psi-mi:e1bjb5_bovin(display_long)|uniprotkb:NPHP4(gene name)|psi-mi:NPHP4(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Murga-Zamalloa et al. (2009) imex:IM-25422|pubmed:20664800 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-11784612|imex:IM-25422-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001098802.1|ensembl:ENSBTAG00000007675(gene)|ensembl:ENSBTAT00000010098(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005929"(cilium)|go:"GO:0031514"(motile cilium)|go:"GO:0090251"(protein localization involved in establishment of planar polarity)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR030642|interpro:IPR036028|interpro:IPR039687 ensembl:ENSBTAG00000008126(gene)|ensembl:ENSBTAT00000045440(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775 - - comment:Detected in precipitate of RPGR-depleted supernatant figure legend:5C|comment:Detected in precipitate of RPGR-depleted supernatant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9913(bovin-retina)|taxid:9913(Bovine retina) - 2016/06/21 2019/04/15 rogid:6Un2TN0XZEE20xRNW0VgSE88hoM9913 rogid:8vqJ2Q28pTxpvFXtK52eEdAupNc9913 rigid:YR46BORdIE4DLclBMznQQdEMcfs false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P59240 uniprotkb:Q9R0X5 intact:EBI-4281265|intact:EBI-4283197|uniprotkb:B1AS30|ensembl:ENSMUSP00000049920|ensembl:ENSMUSP00000080128 intact:EBI-6915619|uniprotkb:A2ADP3|uniprotkb:G9BBQ2|uniprotkb:O88408|uniprotkb:Q9CU92 psi-mi:nphp4_mouse(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:rpgr_mouse(display_long)|uniprotkb:Rpgr(gene name)|psi-mi:Rpgr(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Murga-Zamalloa et al. (2009) imex:IM-25422|pubmed:20664800 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-11784393|imex:IM-25422-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039577(gene)|ensembl:ENSMUST00000056567(transcript)|ensembl:ENSMUST00000081393(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-MMU-2028269|reactome:R-MMU-5620912|refseq:NP_700473.2|refseq:XP_006538935.1|refseq:XP_006538936.1 go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0007601"(visual perception)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0036064"(ciliary basal body)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042073"(intraciliary transport)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0042995"(cell projection)|go:"GO:0060042"(retina morphogenesis in camera-type eye)|go:"GO:0060271"(cilium assembly)|go:"GO:0071482"(cellular response to light stimulus)|go:"GO:0120206"(photoreceptor distal connecting cilium)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|refseq:NP_035415.1|dip:DIP-46319N - - - figure legend:1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-retina)|taxid:10090(Mus musculus retina) - 2016/06/21 2016/06/21 rogid:JEd4JSV1Vqj9kwIbk+tXwUSeg3g10090 rogid:d4RHxOTB6/KXJR/KJ8z32NJljsA10090 rigid:YOPDQEuqKEUT7TML94VEhLCeCP4 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O75161 uniprotkb:Q92834 intact:EBI-4281852|ensembl:ENSP00000367398|uniprotkb:Q8IWC0 intact:EBI-6558417|ensembl:ENSP00000343671|uniprotkb:B1ARN3|uniprotkb:E9PE28|uniprotkb:O00702|uniprotkb:O00737|uniprotkb:Q3KN84|uniprotkb:Q8N5T6|uniprotkb:Q93039|uniprotkb:Q9HD29|uniprotkb:Q9UMR1|intact:EBI-12703128|intact:EBI-16431503 psi-mi:nphp4_human(display_long)|uniprotkb:NPHP4(gene name)|psi-mi:NPHP4(display_short)|uniprotkb:KIAA0673(gene name synonym)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:rpgr_human(display_long)|uniprotkb:RPGR(gene name)|psi-mi:RPGR(display_short)|uniprotkb:RP3(gene name synonym)|uniprotkb:XLRP3(gene name synonym) psi-mi:"MI:0096"(pull down) Murga-Zamalloa et al. (2009) imex:IM-25422|pubmed:20664800 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-11784411|imex:IM-25422-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001278522.1|refseq:NP_001278523.1|refseq:XP_011539518.1|refseq:XP_011539519.1|refseq:XP_011539520.1|ensembl:ENSG00000131697(gene)|ensembl:ENST00000378156(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007165"(signal transduction)|go:"GO:0007632"(visual behavior)|go:"GO:0016604"(nuclear body)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-HSA-2028269|reactome:R-HSA-5620912|go:"GO:0097730"(non-motile cilium)|refseq:NP_055917.1|refseq:XP_006710626.1|refseq:XP_016856486.1 refseq:XP_016885199.1|ensembl:ENSG00000156313(gene)|ensembl:ENST00000339363(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0003723"(RNA binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007601"(visual perception)|go:"GO:0036064"(ciliary basal body)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042073"(intraciliary transport)|go:"GO:0050896"(response to stimulus)|go:"GO:0060271"(cilium assembly)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|rcsb pdb:4JHN|rcsb pdb:4JHP|rcsb pdb:4QAM|refseq:NP_000319.1|refseq:NP_001030025.1 - - - figure legend:1D and E|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/06/21 2016/06/27 rogid:oQi0NY0QgJtrAUUHvnob6BEKcIs9606 rogid:yG3e/pDbkwML2e7J8BMMXY/EVPM9606 rigid:p+fXpE+2G+x4hDRpy0BYyVzL9Sk false 35s radiolabel:?-?|sufficient binding region:1-316 glutathione s tranferase tag:?-?|sufficient binding region:33-392 - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:O15259 uniprotkb:Q92834 intact:EBI-953828|uniprotkb:O14837|ensembl:ENSP00000376953 intact:EBI-6558417|ensembl:ENSP00000343671|uniprotkb:B1ARN3|uniprotkb:E9PE28|uniprotkb:O00702|uniprotkb:O00737|uniprotkb:Q3KN84|uniprotkb:Q8N5T6|uniprotkb:Q93039|uniprotkb:Q9HD29|uniprotkb:Q9UMR1|intact:EBI-12703128|intact:EBI-16431503 psi-mi:nphp1_human(display_long)|uniprotkb:Juvenile nephronophthisis 1 protein(gene name synonym)|uniprotkb:NPHP1(gene name)|psi-mi:NPHP1(display_short)|uniprotkb:NPH1(gene name synonym) psi-mi:rpgr_human(display_long)|uniprotkb:RPGR(gene name)|psi-mi:RPGR(display_short)|uniprotkb:RP3(gene name synonym)|uniprotkb:XLRP3(gene name synonym) psi-mi:"MI:0096"(pull down) Murga-Zamalloa et al. (2009) imex:IM-25422|pubmed:20664800 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-11784459|imex:IM-25422-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000263.2|refseq:NP_001121650.1|refseq:NP_001121651.1|refseq:NP_997064.2|ensembl:ENSG00000144061(gene)|ensembl:ENST00000393272(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0007165"(signal transduction)|go:"GO:0007588"(excretion)|go:"GO:0007632"(visual behavior)|go:"GO:0016020"(membrane)|go:"GO:0030030"(cell projection organization)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031514"(motile cilium)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090251"(protein localization involved in establishment of planar polarity)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR030642|interpro:IPR036028|interpro:IPR039687|mint:O15259|rcsb pdb:1S1N|rcsb pdb:6O1Q|reactome:R-HSA-5620912 refseq:XP_016885199.1|ensembl:ENSG00000156313(gene)|ensembl:ENST00000339363(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0003723"(RNA binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007601"(visual perception)|go:"GO:0036064"(ciliary basal body)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042073"(intraciliary transport)|go:"GO:0050896"(response to stimulus)|go:"GO:0060271"(cilium assembly)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|rcsb pdb:4JHN|rcsb pdb:4JHP|rcsb pdb:4QAM|refseq:NP_000319.1|refseq:NP_001030025.1 - - - figure legend:2D and E|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2016/06/21 2016/06/27 rogid:OPdzsagqWWni+dWU+VLoygacfcg9606 rogid:yG3e/pDbkwML2e7J8BMMXY/EVPM9606 rigid:y7TH0/Jj0MMVBSuDPrCy+z1bXss false 35s radiolabel:?-?|sufficient binding region:243-586 sufficient binding region:33-392|glutathione s tranferase tag:?-? - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography)