#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q8IU80-4	uniprotkb:Q6ZVN8	intact:EBI-11686560	intact:EBI-10900704|uniprotkb:B1ALI7|uniprotkb:Q2PQ63|uniprotkb:Q6IMF6|uniprotkb:Q8NAH2|uniprotkb:Q8WVJ5|ensembl:ENSP00000337014	psi-mi:q8iu80-4(display_long)|uniprotkb:Matriptase-2(gene name synonym)|uniprotkb:UNQ354/PRO618(orf name)|uniprotkb:TMPRSS6(gene name)|psi-mi:TMPRSS6(display_short)	psi-mi:rgmc_human(display_long)|uniprotkb:HJV(gene name)|psi-mi:HJV(display_short)|uniprotkb:HFE2(gene name synonym)|uniprotkb:Hemochromatosis type 2 protein(gene name synonym)|uniprotkb:Hemojuvelin BMP coreceptor(gene name synonym)|uniprotkb:RGM domain family member C(gene name synonym)|uniprotkb:RGMC(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Silvestri et al. (2008)	imex:IM-25099|pubmed:18976966	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11686501|imex:IM-25099-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-11686504(isoform-parent)	refseq:NP_001303696.1|refseq:NP_660320.3|refseq:NP_973733.1|refseq:NP_998817.1|refseq:NP_998818.1|refseq:XP_005272989.1|ensembl:ENSG00000168509(gene)|ensembl:ENST00000336751(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0015026"(coreceptor activity)|go:"GO:0016540"(protein autoprocessing)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0032924"(activin receptor signaling pathway)|go:"GO:0036122"(BMP binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:0070724"(BMP receptor complex)|go:"GO:0071773"(cellular response to BMP stimulus)|go:"GO:0098797"(plasma membrane protein complex)|go:"GO:1990459"(transferrin receptor binding)|go:"GO:1990712"(HFE-transferrin receptor complex)|interpro:IPR009496(Repulsive guidance molecule, C-terminal)|interpro:IPR010536(Repulsive guidance molecule, N-terminal)|interpro:IPR033606|interpro:IPR040287|rcsb pdb:4UI1|rcsb pdb:6Z3L|reactome:R-HSA-373752|dip:DIP-61608N	-	-	-	figure legend:5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2016/03/08	2016/04/11	rogid:XVG3Nxb6mD2FtxZ+9YugTbLUNCo9606	rogid:/AJNZs236A0oBXK8DPnb6jpixgs9606	rigid:NMD5VTYxCr2gzWYZHp6xC2T7iiA	false	flag tag:c-c	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9DBI0-3	uniprotkb:Q6ZVN8	intact:EBI-11695773|ensembl:ENSMUSP00000155549	intact:EBI-10900704|uniprotkb:B1ALI7|uniprotkb:Q2PQ63|uniprotkb:Q6IMF6|uniprotkb:Q8NAH2|uniprotkb:Q8WVJ5|ensembl:ENSP00000337014	psi-mi:q9dbi0-3(display_long)|uniprotkb:Tmprss6(gene name)|psi-mi:Tmprss6(display_short)|uniprotkb:Matriptase-2(gene name synonym)	psi-mi:rgmc_human(display_long)|uniprotkb:HJV(gene name)|psi-mi:HJV(display_short)|uniprotkb:HFE2(gene name synonym)|uniprotkb:Hemochromatosis type 2 protein(gene name synonym)|uniprotkb:Hemojuvelin BMP coreceptor(gene name synonym)|uniprotkb:RGM domain family member C(gene name synonym)|uniprotkb:RGMC(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Silvestri et al. (2008)	imex:IM-25099|pubmed:18976966	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11686700|imex:IM-25099-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-11686706(isoform-parent)|ensembl:ENSMUSG00000016942(gene)|ensembl:ENSMUST00000230159(transcript)	refseq:NP_001303696.1|refseq:NP_660320.3|refseq:NP_973733.1|refseq:NP_998817.1|refseq:NP_998818.1|refseq:XP_005272989.1|ensembl:ENSG00000168509(gene)|ensembl:ENST00000336751(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0015026"(coreceptor activity)|go:"GO:0016540"(protein autoprocessing)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0032924"(activin receptor signaling pathway)|go:"GO:0036122"(BMP binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:0070724"(BMP receptor complex)|go:"GO:0071773"(cellular response to BMP stimulus)|go:"GO:0098797"(plasma membrane protein complex)|go:"GO:1990459"(transferrin receptor binding)|go:"GO:1990712"(HFE-transferrin receptor complex)|interpro:IPR009496(Repulsive guidance molecule, C-terminal)|interpro:IPR010536(Repulsive guidance molecule, N-terminal)|interpro:IPR033606|interpro:IPR040287|rcsb pdb:4UI1|rcsb pdb:6Z3L|reactome:R-HSA-373752|dip:DIP-61608N	-	isoform-comment:No experimental confirmation available.	-	figure legend:5B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2016/03/08	2016/05/10	rogid:2jaeyi/mmCwd6B2lgBqWMuwJUwg10090	rogid:/AJNZs236A0oBXK8DPnb6jpixgs9606	rigid:YRVc9kAZCeHsO118pJCWYf0/gBo	false	flag tag:c-c	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q8IU80-4	uniprotkb:Q6ZVN8	intact:EBI-11686560	intact:EBI-10900704|uniprotkb:B1ALI7|uniprotkb:Q2PQ63|uniprotkb:Q6IMF6|uniprotkb:Q8NAH2|uniprotkb:Q8WVJ5|ensembl:ENSP00000337014	psi-mi:q8iu80-4(display_long)|uniprotkb:Matriptase-2(gene name synonym)|uniprotkb:UNQ354/PRO618(orf name)|uniprotkb:TMPRSS6(gene name)|psi-mi:TMPRSS6(display_short)	psi-mi:rgmc_human(display_long)|uniprotkb:HJV(gene name)|psi-mi:HJV(display_short)|uniprotkb:HFE2(gene name synonym)|uniprotkb:Hemochromatosis type 2 protein(gene name synonym)|uniprotkb:Hemojuvelin BMP coreceptor(gene name synonym)|uniprotkb:RGM domain family member C(gene name synonym)|uniprotkb:RGMC(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Silvestri et al. (2008)	imex:IM-25099|pubmed:18976966	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11686569|imex:IM-25099-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-11686504(isoform-parent)	refseq:NP_001303696.1|refseq:NP_660320.3|refseq:NP_973733.1|refseq:NP_998817.1|refseq:NP_998818.1|refseq:XP_005272989.1|ensembl:ENSG00000168509(gene)|ensembl:ENST00000336751(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0015026"(coreceptor activity)|go:"GO:0016540"(protein autoprocessing)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0032924"(activin receptor signaling pathway)|go:"GO:0036122"(BMP binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:0070724"(BMP receptor complex)|go:"GO:0071773"(cellular response to BMP stimulus)|go:"GO:0098797"(plasma membrane protein complex)|go:"GO:1990459"(transferrin receptor binding)|go:"GO:1990712"(HFE-transferrin receptor complex)|interpro:IPR009496(Repulsive guidance molecule, C-terminal)|interpro:IPR010536(Repulsive guidance molecule, N-terminal)|interpro:IPR033606|interpro:IPR040287|rcsb pdb:4UI1|rcsb pdb:6Z3L|reactome:R-HSA-373752|dip:DIP-61608N	-	-	-	figure legend:5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2016/03/08	2016/04/11	rogid:XVG3Nxb6mD2FtxZ+9YugTbLUNCo9606	rogid:/AJNZs236A0oBXK8DPnb6jpixgs9606	rigid:NMD5VTYxCr2gzWYZHp6xC2T7iiA	false	flag tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)