#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P62158 uniprotkb:O43303 intact:EBI-397435|uniprotkb:P02593|uniprotkb:P70667|uniprotkb:P99014|uniprotkb:Q13942|uniprotkb:Q53S29|uniprotkb:Q61379|uniprotkb:Q61380|uniprotkb:Q96HK3|uniprotkb:P0DP25|uniprotkb:P0DP24|uniprotkb:P0DP23 intact:EBI-1566217|uniprotkb:O43335|uniprotkb:Q68DV9|uniprotkb:Q8NE13|uniprotkb:B7WP23|ensembl:ENSP00000370803 psi-mi:calm_human(display_long)|uniprotkb:CALM1(gene name)|psi-mi:CALM1(display_short)|uniprotkb:CALM(gene name synonym)|uniprotkb:CAM(gene name synonym)|uniprotkb:CAM1(gene name synonym)|uniprotkb:CALM2(gene name)|psi-mi:CALM2(display_short)|uniprotkb:CAMB(gene name synonym)|uniprotkb:CALM3(gene name)|psi-mi:CALM3(display_short)|uniprotkb:CAM3(gene name synonym)|uniprotkb:CAMC(gene name synonym)|uniprotkb:CAMIII(gene name synonym)|uniprotkb:CAM2(gene name synonym)|uniprotkb:CALML2(gene name synonym) psi-mi:cp110_human(display_long)|uniprotkb:CP110(gene name synonym)|uniprotkb:CCP110(gene name)|psi-mi:CCP110(display_short)|uniprotkb:CEP110(gene name synonym)|uniprotkb:KIAA0419(gene name synonym)|uniprotkb:Centrosomal protein of 110 kDa(gene name synonym) psi-mi:"MI:0018"(two hybrid) Tsang et al. (2008) pubmed:18694559|imex:IM-25243 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-11692460|imex:IM-25243-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:3SUI|rcsb pdb:2LGF|rcsb pdb:2LQC|rcsb pdb:2LQP|rcsb pdb:2Y4V|rcsb pdb:4JQ0|rcsb pdb:4LZX|rcsb pdb:4M1L|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|rcsb pdb:3J41|rcsb pdb:2LL6|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0030017"(sarcomere)|go:"GO:0030801"(obsolete positive regulation of cyclic nucleotide metabolic process)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0051343"(positive regulation of cyclic-nucleotide phosphodiesterase activity)|go:"GO:0072542"(protein phosphatase activator activity)|go:"GO:1901844"(regulation of cell communication by electrical coupling involved in cardiac conduction)|rcsb pdb:2LV6|rcsb pdb:2N6A|refseq:NP_001734.1|refseq:NP_005175.2|refseq:NP_008819.1|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005876"(spindle microtubule)|go:"GO:0000922"(spindle pole)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005980"(glycogen catabolic process)|go:"GO:0006936"(muscle contraction)|go:"GO:0060315"(negative regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0002576"(platelet degranulation)|go:"GO:0060316"(positive regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0050999"(regulation of nitric-oxide synthase activity)|rcsb pdb:1AJI|rcsb pdb:1CDL|rcsb pdb:1CLL|rcsb pdb:1CTR|rcsb pdb:1IWQ|rcsb pdb:1J7O|rcsb pdb:1J7P|rcsb pdb:1K90|rcsb pdb:1K93|rcsb pdb:1L7Z|rcsb pdb:1LVC|rcsb pdb:1NKF|rcsb pdb:1PK0|rcsb pdb:1S26|rcsb pdb:1SK6|rcsb pdb:1SW8|rcsb pdb:1WRZ|rcsb pdb:1XFU|rcsb pdb:1XFV|rcsb pdb:1XFW|rcsb pdb:1XFX|rcsb pdb:1XFY|rcsb pdb:1XFZ|rcsb pdb:1Y6W|rcsb pdb:1YR5|rcsb pdb:1YRT|rcsb pdb:1YRU|rcsb pdb:1ZOT|rcsb pdb:1ZUZ|rcsb pdb:2BE6|rcsb pdb:2F3Y|rcsb pdb:2F3Z|rcsb pdb:2HF5|rcsb pdb:2I08|rcsb pdb:2JZI|rcsb pdb:2K0E|rcsb pdb:2K0F|rcsb pdb:2K0J|rcsb pdb:2K61|rcsb pdb:2KNE|rcsb pdb:2KUG|rcsb pdb:2KUH|rcsb pdb:2L53|rcsb pdb:2L7L|rcsb pdb:2R28|rcsb pdb:2V01|rcsb pdb:2V02|rcsb pdb:2VAY|rcsb pdb:2W73|rcsb pdb:2WEL|rcsb pdb:2X0G|rcsb pdb:3BYA|rcsb pdb:3DVE|rcsb pdb:3DVJ|rcsb pdb:3DVK|rcsb pdb:3DVM|rcsb pdb:3EWT|rcsb pdb:3EWV|rcsb pdb:3G43|rcsb pdb:3HR4|rcsb pdb:3O77|rcsb pdb:3O78|rcsb pdb:3OXQ|rcsb pdb:3UCT|rcsb pdb:3UCW|rcsb pdb:3UCY|rcsb pdb:4DCK|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0000165"(MAPK cascade)|rcsb pdb:2M0J|rcsb pdb:2M0K|rcsb pdb:4UMO|rcsb pdb:4V0C|go:"GO:0031982"(vesicle)|rcsb pdb:4Q5U|rcsb pdb:4UPU|reactome:R-HSA-2672351|reactome:R-HSA-418359|reactome:R-HSA-425561|reactome:R-HSA-5576892|reactome:R-HSA-5578775|reactome:R-HSA-936837|refseq:NP_001292555.1|rcsb pdb:4OVN|rcsb pdb:5COC|go:"GO:0021762"(substantia nigra development)|go:"GO:0070062"(extracellular exosome)|rcsb pdb:4BW7|rcsb pdb:4BW8|rcsb pdb:4L79|rcsb pdb:5DBR|rcsb pdb:4DJC|rcsb pdb:2M55|rcsb pdb:2LL7|go:"GO:0019855"(calcium channel inhibitor activity)|go:"GO:0001975"(response to amphetamine)|go:"GO:0007190"(activation of adenylate cyclase activity)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030426"(growth cone)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051412"(response to corticosterone)|go:"GO:1901841"(regulation of high voltage-gated calcium channel activity)|rcsb pdb:2N77|go:"GO:0032991"(protein-containing complex)|go:"GO:0006479"(protein methylation)|go:"GO:0014069"(postsynaptic density)|rcsb pdb:5DSU|reactome:R-HSA-8876725|rcsb pdb:4GOW|rcsb pdb:4Q57|go:"GO:0043647"(inositol phosphate metabolic process)|go:"GO:0022400"(regulation of rhodopsin mediated signaling pathway)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031432"(titin binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0031997"(N-terminal myristoylation domain binding)|go:"GO:0043274"(phospholipase binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055117"(regulation of cardiac muscle contraction)|rcsb pdb:2MG5|go:"GO:0005088"|go:"GO:0007223"(Wnt signaling pathway, calcium modulating pathway)|go:"GO:0008440"(inositol-1,4,5-trisphosphate 3-kinase activity)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0005634"(nucleus)|rcsb pdb:4JPZ|ensembl:ENST00000272298|ensembl:ENST00000291295|ensembl:ENST00000356978|ensembl:ENST00000596362|refseq:NP_001292553.1|refseq:NP_001292554.1|rcsb pdb:4BYF|reactome:R-HSA-111932|reactome:R-HSA-111933|reactome:R-HSA-111957|reactome:R-HSA-111997|reactome:R-HSA-114608|reactome:R-HSA-1445148|reactome:R-HSA-1474151|reactome:R-HSA-180024|reactome:R-HSA-1855204|reactome:R-HSA-203615|reactome:R-HSA-2514859|reactome:R-HSA-2871809|reactome:R-HSA-4086398|reactome:R-HSA-442717|reactome:R-HSA-442729|reactome:R-HSA-442745|reactome:R-HSA-442982|reactome:R-HSA-445355|reactome:R-HSA-451308|reactome:R-HSA-5218920|reactome:R-HSA-5218921|reactome:R-HSA-5607763|reactome:R-HSA-5626467|reactome:R-HSA-5627123|reactome:R-HSA-5673001|reactome:R-HSA-70221|reactome:R-HSA-983695|ensembl:ENSG00000143933|ensembl:ENSG00000160014|ensembl:ENSG00000198668|ensembl:ENSP00000272298|ensembl:ENSP00000291295|ensembl:ENSP00000349467|ensembl:ENSP00000472141|rcsb pdb:5NIN|rcsb pdb:5VMS|rcsb pdb:5WSU|rcsb pdb:5WSV|rcsb pdb:6U39|rcsb pdb:6U3A|rcsb pdb:6U3B|rcsb pdb:6U3D|rcsb pdb:2N8J|rcsb pdb:5GGM|rcsb pdb:5J8H|reactome:R-HSA-163615|reactome:R-HSA-5210891|refseq:NP_001316851.1|refseq:NP_001316852.1|refseq:NP_001316853.1|refseq:NP_001316854.1|refseq:NP_001316855.1|rcsb pdb:2N27|rcsb pdb:5DOW|rcsb pdb:5I0I|rcsb pdb:5J03|rcsb pdb:5K7L|rcsb pdb:5K8Q|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0043388"(positive regulation of DNA binding)|dip:DIP-31794N|rcsb pdb:1UP5|rcsb pdb:5JQA|rcsb pdb:5JTH|rcsb pdb:5OEO|rcsb pdb:5TP5|rcsb pdb:5TP6|rcsb pdb:5V02|rcsb pdb:5V03|rcsb pdb:5V7X|rcsb pdb:5WBX|rcsb pdb:5WC5|rcsb pdb:6B8L|rcsb pdb:6B8M|rcsb pdb:6B8N|rcsb pdb:6B8P|rcsb pdb:6B8Q|rcsb pdb:6C1D|rcsb pdb:6C1G|rcsb pdb:6C1H|rcsb pdb:6CNM|rcsb pdb:6CNN|rcsb pdb:6CNO|rcsb pdb:6FEG|rcsb pdb:6FEH|reactome:R-HSA-2025928|reactome:R-HSA-2151201|go:"GO:0034704"(calcium channel complex)|go:"GO:0010856"(adenylate cyclase activator activity)|go:"GO:0051186"(obsolete cofactor metabolic process)|go:"GO:0075206"(obsolete positive regulation by host of symbiont cAMP-mediated signal transduction)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|interpro:IPR039030|go:"GO:1902494"(catalytic complex)|go:"GO:0043234"|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0030819"(obsolete positive regulation of cAMP biosynthetic process)|rcsb pdb:6BUT|rcsb pdb:6DAD|rcsb pdb:6DAE|rcsb pdb:6DAF|rcsb pdb:6DAH|rcsb pdb:6E2F|rcsb pdb:6E2G|rcsb pdb:6EEB|rcsb pdb:6GDK|rcsb pdb:6GDL|rcsb pdb:6HCS|rcsb pdb:6JI8|rcsb pdb:6JII|rcsb pdb:6JIU|rcsb pdb:6JIY|rcsb pdb:6JRS|rcsb pdb:6JV2|rcsb pdb:6K4K|rcsb pdb:6K4L|rcsb pdb:6K4R|rcsb pdb:6MUD|rcsb pdb:6MUE|rcsb pdb:6N5W|rcsb pdb:6O5G|reactome:R-HSA-438066|reactome:R-HSA-442720|reactome:R-HSA-5673000|reactome:R-HSA-6802946|reactome:R-HSA-6802949|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9009391|reactome:R-HSA-9022535|reactome:R-HSA-9022692|reactome:R-HSA-9617324|reactome:R-HSA-9619229|reactome:R-HSA-9619483|reactome:R-HSA-9620244|go:"GO:0019722"(calcium-mediated signaling)|rcsb pdb:6PBX|rcsb pdb:6PBY|reactome:R-HSA-9649948|go:"GO:0005623"(obsolete cell)|rcsb pdb:6HR1|rcsb pdb:6OS4|rcsb pdb:6Y4P|rcsb pdb:6Y94|rcsb pdb:6Y95|reactome:R-HSA-9664323|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0016032"(viral process)|rcsb pdb:6M7H|rcsb pdb:6UZZ|rcsb pdb:6V00|rcsb pdb:6V01|rcsb pdb:6PLM|rcsb pdb:6S5T|rcsb pdb:6SZ5|rcsb pdb:6XXF|rcsb pdb:6Y4O refseq:NP_001310498.1|refseq:NP_001185951.2|refseq:NP_001310499.1|refseq:NP_001310500.1|refseq:NP_001310501.1|refseq:NP_055526.4|refseq:XP_011544293.1|refseq:XP_011544294.1|refseq:XP_016879397.1|dip:DIP-39892N|ensembl:ENSG00000103540(gene)|ensembl:ENST00000381396(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007099"(centriole replication)|go:"GO:0032053"(ciliary basal body organization)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0051298"(centrosome duplication)|go:"GO:1902018"(negative regulation of cilium assembly)|go:"GO:1903723"(negative regulation of centriole elongation)|interpro:IPR033207|mint:O43303|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5689880|reactome:R-HSA-8854518|reactome:R-HSA-9013424 - - - figure legend:1A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2016/05/03 2016/05/03 rogid:tTYcOd9bOh211njZVz7cYVybAMQ9606 rogid:Gvda4RoDRcY+G50iRW5T+haubps9606 rigid:v8uBE/eskrl3wVfY/JoqUvi/6B8 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O15078 uniprotkb:O43303 intact:EBI-1811944|uniprotkb:Q1PSK5|uniprotkb:Q66GS8|uniprotkb:Q9H2G6|uniprotkb:Q9H6Q7|uniprotkb:Q9H8I0|ensembl:ENSP00000448012 intact:EBI-1566217|uniprotkb:O43335|uniprotkb:Q68DV9|uniprotkb:Q8NE13|uniprotkb:B7WP23|ensembl:ENSP00000370803 psi-mi:ce290_human(display_long)|uniprotkb:CEP290(gene name)|psi-mi:CEP290(display_short)|uniprotkb:KIAA0373(gene name synonym)|uniprotkb:NPHP6(gene name synonym)|uniprotkb:Nephrocystin-6(gene name synonym)|uniprotkb:Tumor antigen se2-2(gene name synonym)|uniprotkb:Cancer/testis antigen 87(gene name synonym)|uniprotkb:BBS14(gene name synonym)|uniprotkb:Bardet-Biedl syndrome 14 protein(gene name synonym) psi-mi:cp110_human(display_long)|uniprotkb:CP110(gene name synonym)|uniprotkb:CCP110(gene name)|psi-mi:CCP110(display_short)|uniprotkb:CEP110(gene name synonym)|uniprotkb:KIAA0419(gene name synonym)|uniprotkb:Centrosomal protein of 110 kDa(gene name synonym) psi-mi:"MI:0018"(two hybrid) Tsang et al. (2008) pubmed:18694559|imex:IM-25243 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-11692465|imex:IM-25243-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079390.3|dip:DIP-46541N|ensembl:ENSG00000198707(gene)|ensembl:ENST00000552810(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0030902"(hindbrain development)|go:"GO:0030916"(otic vesicle formation)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035580"(specific granule lumen)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048793"(pronephros development)|go:"GO:0060271"(cilium assembly)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0097711"(ciliary basal body-plasma membrane docking)|go:"GO:1905349"(ciliary transition zone assembly)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR026201|interpro:IPR032321|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-6798695|reactome:R-HSA-8854518 refseq:NP_001310498.1|refseq:NP_001185951.2|refseq:NP_001310499.1|refseq:NP_001310500.1|refseq:NP_001310501.1|refseq:NP_055526.4|refseq:XP_011544293.1|refseq:XP_011544294.1|refseq:XP_016879397.1|dip:DIP-39892N|ensembl:ENSG00000103540(gene)|ensembl:ENST00000381396(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007099"(centriole replication)|go:"GO:0032053"(ciliary basal body organization)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0051298"(centrosome duplication)|go:"GO:1902018"(negative regulation of cilium assembly)|go:"GO:1903723"(negative regulation of centriole elongation)|interpro:IPR033207|mint:O43303|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5689880|reactome:R-HSA-8854518|reactome:R-HSA-9013424 - - - figure legend:1A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2016/05/03 2016/05/03 rogid:89HbDVs4UVmzftFFLO/pHklTiUQ9606 rogid:Gvda4RoDRcY+G50iRW5T+haubps9606 rigid:Mt5EJbMSbMebEHqzvQUMv9X5pjc false sufficient binding region:237-526 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P11137 uniprotkb:O43303 intact:EBI-2682460|uniprotkb:Q17S04|uniprotkb:Q99975|uniprotkb:Q99976|uniprotkb:Q8IUX2|ensembl:ENSP00000353508|ensembl:ENSP00000507035 intact:EBI-1566217|uniprotkb:O43335|uniprotkb:Q68DV9|uniprotkb:Q8NE13|uniprotkb:B7WP23|ensembl:ENSP00000370803 psi-mi:mtap2_human(display_long)|uniprotkb:MAP2(gene name)|psi-mi:MAP2(display_short) psi-mi:cp110_human(display_long)|uniprotkb:CP110(gene name synonym)|uniprotkb:CCP110(gene name)|psi-mi:CCP110(display_short)|uniprotkb:CEP110(gene name synonym)|uniprotkb:KIAA0419(gene name synonym)|uniprotkb:Centrosomal protein of 110 kDa(gene name synonym) psi-mi:"MI:0018"(two hybrid) Tsang et al. (2008) pubmed:18694559|imex:IM-25243 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-11692480|imex:IM-25243-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002365.3|refseq:NP_114033.2|refseq:NP_114035.2|refseq:NP_001034627.1|go:"GO:1902513"(regulation of organelle transport along microtubule)|go:"GO:1902737"(dendritic filopodium)|go:"GO:1903744"(positive regulation of anterograde synaptic vesicle transport)|go:"GO:1903827"|go:"GO:1904527"(negative regulation of microtubule binding)|go:"GO:1990635"(proximal dendrite)|go:"GO:1990769"(proximal neuron projection)|go:"GO:2000575"(obsolete negative regulation of microtubule motor activity)|interpro:IPR001084(Tubulin-binding Tau protein)|interpro:IPR013588(MAP2/Tau projection)|interpro:IPR030797|mint:P11137|ensembl:ENSG00000078018(gene)|ensembl:ENST00000360351(transcript)|ensembl:ENST00000682079(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0008017"(microtubule binding)|go:"GO:0016358"(dendrite development)|go:"GO:0021954"(central nervous system neuron development)|go:"GO:0030425"(dendrite)|go:"GO:0030517"(negative regulation of axon extension)|go:"GO:0031113"(regulation of microtubule polymerization)|go:"GO:0031115"(negative regulation of microtubule polymerization)|go:"GO:0031175"(neuron projection development)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043194"(axon initial segment)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043203"(axon hillock)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044307"(dendritic branch)|go:"GO:0048156"(tau protein binding)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0097441"(basal dendrite)|go:"GO:0150001"(primary dendrite)|go:"GO:0150002"(distal dendrite)|go:"GO:0150014"(apical distal dendrite)|go:"GO:1901953"(positive regulation of anterograde dense core granule transport)|refseq:XP_016859607.1|refseq:XP_016859612.1|refseq:XP_016859613.1|refseq:XP_016859627.1|refseq:XP_016859628.1|dip:DIP-577N|refseq:XP_016859629.1 refseq:NP_001310498.1|refseq:NP_001185951.2|refseq:NP_001310499.1|refseq:NP_001310500.1|refseq:NP_001310501.1|refseq:NP_055526.4|refseq:XP_011544293.1|refseq:XP_011544294.1|refseq:XP_016879397.1|dip:DIP-39892N|ensembl:ENSG00000103540(gene)|ensembl:ENST00000381396(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007099"(centriole replication)|go:"GO:0032053"(ciliary basal body organization)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0051298"(centrosome duplication)|go:"GO:1902018"(negative regulation of cilium assembly)|go:"GO:1903723"(negative regulation of centriole elongation)|interpro:IPR033207|mint:O43303|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5689880|reactome:R-HSA-8854518|reactome:R-HSA-9013424 - - - figure legend:1A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2016/05/03 2016/05/03 rogid:IfbwC7748mUgLEmuxR5Zd2TEQ/09606 rogid:Gvda4RoDRcY+G50iRW5T+haubps9606 rigid:a2JOxwJSUCNbBwO6YKRG2KE18ew false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q5QP82 uniprotkb:O43303 intact:EBI-723230|uniprotkb:A4VCJ5|uniprotkb:Q32NE2|uniprotkb:Q96ET5|uniprotkb:Q9BTQ5|uniprotkb:Q9H5P6|uniprotkb:Q8N2Q5|ensembl:ENSP00000366953|intact:EBI-2559068 intact:EBI-1566217|uniprotkb:O43335|uniprotkb:Q68DV9|uniprotkb:Q8NE13|uniprotkb:B7WP23|ensembl:ENSP00000370803 psi-mi:dca10_human(display_long)|uniprotkb:DCAF10(gene name)|psi-mi:DCAF10(display_short)|uniprotkb:WDR32(gene name synonym)|uniprotkb:WD repeat-containing protein 32(gene name synonym) psi-mi:cp110_human(display_long)|uniprotkb:CP110(gene name synonym)|uniprotkb:CCP110(gene name)|psi-mi:CCP110(display_short)|uniprotkb:CEP110(gene name synonym)|uniprotkb:KIAA0419(gene name synonym)|uniprotkb:Centrosomal protein of 110 kDa(gene name synonym) psi-mi:"MI:0018"(two hybrid) Tsang et al. (2008) pubmed:18694559|imex:IM-25243 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-11692484|imex:IM-25243-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_077321.3|ensembl:ENSG00000122741(gene)|ensembl:ENST00000377724(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|interpro:IPR039085|mint:Q5QP82|reactome:R-HSA-8951664|interpro:IPR001680(WD40 repeat)|refseq:NP_001273739.1|refseq:XP_005251634.1 refseq:NP_001310498.1|refseq:NP_001185951.2|refseq:NP_001310499.1|refseq:NP_001310500.1|refseq:NP_001310501.1|refseq:NP_055526.4|refseq:XP_011544293.1|refseq:XP_011544294.1|refseq:XP_016879397.1|dip:DIP-39892N|ensembl:ENSG00000103540(gene)|ensembl:ENST00000381396(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007099"(centriole replication)|go:"GO:0032053"(ciliary basal body organization)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0051298"(centrosome duplication)|go:"GO:1902018"(negative regulation of cilium assembly)|go:"GO:1903723"(negative regulation of centriole elongation)|interpro:IPR033207|mint:O43303|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5689880|reactome:R-HSA-8854518|reactome:R-HSA-9013424 - - - figure legend:1A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2016/05/03 2016/05/03 rogid:0mrMrjLK7HAJLVaAg/spKCEKOAo9606 rogid:Gvda4RoDRcY+G50iRW5T+haubps9606 rigid:PpiNJX3zLOfyUKgrUnZhFaxUwlY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O43719 uniprotkb:O43303 intact:EBI-720468|uniprotkb:Q59G06|uniprotkb:Q99730|uniprotkb:D3DWG9|intact:EBI-28971035|ensembl:ENSP00000218364|ensembl:ENSP00000442699 intact:EBI-1566217|uniprotkb:O43335|uniprotkb:Q68DV9|uniprotkb:Q8NE13|uniprotkb:B7WP23|ensembl:ENSP00000370803 psi-mi:htsf1_human(display_long)|uniprotkb:HTATSF1(gene name)|psi-mi:HTATSF1(display_short) psi-mi:cp110_human(display_long)|uniprotkb:CP110(gene name synonym)|uniprotkb:CCP110(gene name)|psi-mi:CCP110(display_short)|uniprotkb:CEP110(gene name synonym)|uniprotkb:KIAA0419(gene name synonym)|uniprotkb:Centrosomal protein of 110 kDa(gene name synonym) psi-mi:"MI:0018"(two hybrid) Tsang et al. (2008) pubmed:18694559|imex:IM-25243 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-11692488|imex:IM-25243-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000218364|ensembl:ENSP00000442699|refseq:NP_001156752.1|refseq:NP_055315.2|refseq:XP_005262461.1|dip:DIP-42095N|ensembl:ENSG00000102241(gene)|ensembl:ENST00000218364(transcript)|ensembl:ENST00000535601(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005684"(U2-type spliceosomal complex)|go:"GO:0005686"(U2 snRNP)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0019079"(viral genome replication)|go:"GO:0032784"(regulation of DNA-templated transcription, elongation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034392|interpro:IPR034393|interpro:IPR035979|mint:O43719|rcsb pdb:2DIT|rcsb pdb:6N3D|rcsb pdb:6N3E|rcsb pdb:6N3F|rcsb pdb:6NSX|rcsb pdb:6Y50|rcsb pdb:6Y53|rcsb pdb:6Y5Q refseq:NP_001310498.1|refseq:NP_001185951.2|refseq:NP_001310499.1|refseq:NP_001310500.1|refseq:NP_001310501.1|refseq:NP_055526.4|refseq:XP_011544293.1|refseq:XP_011544294.1|refseq:XP_016879397.1|dip:DIP-39892N|ensembl:ENSG00000103540(gene)|ensembl:ENST00000381396(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007099"(centriole replication)|go:"GO:0032053"(ciliary basal body organization)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0051298"(centrosome duplication)|go:"GO:1902018"(negative regulation of cilium assembly)|go:"GO:1903723"(negative regulation of centriole elongation)|interpro:IPR033207|mint:O43303|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5689880|reactome:R-HSA-8854518|reactome:R-HSA-9013424 - - - figure legend:1A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2016/05/03 2016/05/03 rogid:PttL+7D+505QAmcHRGNsc40haPY9606 rogid:Gvda4RoDRcY+G50iRW5T+haubps9606 rigid:qG9C7virAfFGrXhmM/gp7MvZEbM false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O95861 uniprotkb:O43303 intact:EBI-1055095|uniprotkb:Q8WVL5|uniprotkb:Q9UGJ3|uniprotkb:A8K7C8|uniprotkb:D3DTA9|uniprotkb:B4DPS5|uniprotkb:B4DUS9|ensembl:ENSP00000318852|ensembl:ENSP00000446828 intact:EBI-1566217|uniprotkb:O43335|uniprotkb:Q68DV9|uniprotkb:Q8NE13|uniprotkb:B7WP23|ensembl:ENSP00000370803 psi-mi:bpnt1_human(display_long)|uniprotkb:Bisphosphate 3'-nucleotidase 1(gene name synonym)|uniprotkb:BPNT1(gene name)|psi-mi:BPNT1(display_short)|uniprotkb:PAP-inositol 1,4-phosphatase(gene name synonym) psi-mi:cp110_human(display_long)|uniprotkb:CP110(gene name synonym)|uniprotkb:CCP110(gene name)|psi-mi:CCP110(display_short)|uniprotkb:CEP110(gene name synonym)|uniprotkb:KIAA0419(gene name synonym)|uniprotkb:Centrosomal protein of 110 kDa(gene name synonym) psi-mi:"MI:0018"(two hybrid) Tsang et al. (2008) pubmed:18694559|imex:IM-25243 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-11692492|imex:IM-25243-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006076.4|refseq:NP_001273078.1|refseq:NP_001273079.1|refseq:XP_005273057.1|refseq:NP_001273080.1|ensembl:ENSG00000162813(gene)|ensembl:ENST00000322067(transcript)|ensembl:ENST00000469520(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0007399"(nervous system development)|go:"GO:0008441"("3'(2'),5'-bisphosphate nucleotidase activity")|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0046855"(inositol phosphate dephosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050427"(3'-phosphoadenosine 5'-phosphosulfate metabolic process)|interpro:IPR000760(Inositol monophosphatase)|interpro:IPR020550|interpro:IPR020583|rcsb pdb:2WEF|reactome:R-HSA-156584|refseq:XP_016855532.1 refseq:NP_001310498.1|refseq:NP_001185951.2|refseq:NP_001310499.1|refseq:NP_001310500.1|refseq:NP_001310501.1|refseq:NP_055526.4|refseq:XP_011544293.1|refseq:XP_011544294.1|refseq:XP_016879397.1|dip:DIP-39892N|ensembl:ENSG00000103540(gene)|ensembl:ENST00000381396(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007099"(centriole replication)|go:"GO:0032053"(ciliary basal body organization)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0051298"(centrosome duplication)|go:"GO:1902018"(negative regulation of cilium assembly)|go:"GO:1903723"(negative regulation of centriole elongation)|interpro:IPR033207|mint:O43303|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5689880|reactome:R-HSA-8854518|reactome:R-HSA-9013424 - - - figure legend:1A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2016/05/03 2016/05/03 rogid:sMaU5Z6Qy2J2O7bTcoR3gRyHNik9606 rogid:Gvda4RoDRcY+G50iRW5T+haubps9606 rigid:vVgVnnW7WWPZnM6NiTtd9tfW+UQ false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q12792 uniprotkb:O43303 intact:EBI-1056675|uniprotkb:Q6NUK9|uniprotkb:A8K5A8|uniprotkb:Q59G07|uniprotkb:Q5U0B1|uniprotkb:Q6FHJ1|uniprotkb:Q6FHL6|uniprotkb:Q86XL6|uniprotkb:Q8TCD3|ensembl:ENSP00000378886|uniprotkb:B3KXS6|uniprotkb:B4DLX9 intact:EBI-1566217|uniprotkb:O43335|uniprotkb:Q68DV9|uniprotkb:Q8NE13|uniprotkb:B7WP23|ensembl:ENSP00000370803 psi-mi:twf1_human(display_long)|uniprotkb:TWF1(gene name)|psi-mi:TWF1(display_short)|uniprotkb:PTK9(gene name synonym)|uniprotkb:Protein A6(gene name synonym)|uniprotkb:Protein tyrosine kinase 9(gene name synonym) psi-mi:cp110_human(display_long)|uniprotkb:CP110(gene name synonym)|uniprotkb:CCP110(gene name)|psi-mi:CCP110(display_short)|uniprotkb:CEP110(gene name synonym)|uniprotkb:KIAA0419(gene name synonym)|uniprotkb:Centrosomal protein of 110 kDa(gene name synonym) psi-mi:"MI:0018"(two hybrid) Tsang et al. (2008) pubmed:18694559|imex:IM-25243 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-11692496|imex:IM-25243-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000151239(gene)|ensembl:ENST00000395510(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0010591"(regulation of lamellipodium assembly)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0030016"(myofibril)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030175"(filopodium)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0032587"(ruffle membrane)|go:"GO:0042989"(sequestering of actin monomers)|go:"GO:0043538"(regulation of actin phosphorylation)|go:"GO:0045296"(cadherin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|interpro:IPR002108(Actin-binding, cofilin/tropomyosin type)|interpro:IPR028458|interpro:IPR029006|mint:Q12792|refseq:NP_001229326.1|refseq:NP_002813.3|rcsb pdb:7CCC|reactome:R-HSA-9013418|reactome:R-HSA-9662360|reactome:R-HSA-9662361 refseq:NP_001310498.1|refseq:NP_001185951.2|refseq:NP_001310499.1|refseq:NP_001310500.1|refseq:NP_001310501.1|refseq:NP_055526.4|refseq:XP_011544293.1|refseq:XP_011544294.1|refseq:XP_016879397.1|dip:DIP-39892N|ensembl:ENSG00000103540(gene)|ensembl:ENST00000381396(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007099"(centriole replication)|go:"GO:0032053"(ciliary basal body organization)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0051298"(centrosome duplication)|go:"GO:1902018"(negative regulation of cilium assembly)|go:"GO:1903723"(negative regulation of centriole elongation)|interpro:IPR033207|mint:O43303|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5689880|reactome:R-HSA-8854518|reactome:R-HSA-9013424 - - - figure legend:1A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2016/05/03 2016/05/03 rogid:5yv7DC8rsBmxmXtzv40wJ/U154c9606 rogid:Gvda4RoDRcY+G50iRW5T+haubps9606 rigid:az5/h6pK7mAoAtitR9/0tqcCFJ8 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O15078 uniprotkb:O43303 intact:EBI-1811944|uniprotkb:Q1PSK5|uniprotkb:Q66GS8|uniprotkb:Q9H2G6|uniprotkb:Q9H6Q7|uniprotkb:Q9H8I0|ensembl:ENSP00000448012 intact:EBI-1566217|uniprotkb:O43335|uniprotkb:Q68DV9|uniprotkb:Q8NE13|uniprotkb:B7WP23|ensembl:ENSP00000370803 psi-mi:ce290_human(display_long)|uniprotkb:CEP290(gene name)|psi-mi:CEP290(display_short)|uniprotkb:KIAA0373(gene name synonym)|uniprotkb:NPHP6(gene name synonym)|uniprotkb:Nephrocystin-6(gene name synonym)|uniprotkb:Tumor antigen se2-2(gene name synonym)|uniprotkb:Cancer/testis antigen 87(gene name synonym)|uniprotkb:BBS14(gene name synonym)|uniprotkb:Bardet-Biedl syndrome 14 protein(gene name synonym) psi-mi:cp110_human(display_long)|uniprotkb:CP110(gene name synonym)|uniprotkb:CCP110(gene name)|psi-mi:CCP110(display_short)|uniprotkb:CEP110(gene name synonym)|uniprotkb:KIAA0419(gene name synonym)|uniprotkb:Centrosomal protein of 110 kDa(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Tsang et al. (2008) pubmed:18694559|imex:IM-25243 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-11692509|imex:IM-25243-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079390.3|dip:DIP-46541N|ensembl:ENSG00000198707(gene)|ensembl:ENST00000552810(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0030902"(hindbrain development)|go:"GO:0030916"(otic vesicle formation)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035580"(specific granule lumen)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048793"(pronephros development)|go:"GO:0060271"(cilium assembly)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0097711"(ciliary basal body-plasma membrane docking)|go:"GO:1905349"(ciliary transition zone assembly)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR026201|interpro:IPR032321|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-6798695|reactome:R-HSA-8854518 refseq:NP_001310498.1|refseq:NP_001185951.2|refseq:NP_001310499.1|refseq:NP_001310500.1|refseq:NP_001310501.1|refseq:NP_055526.4|refseq:XP_011544293.1|refseq:XP_011544294.1|refseq:XP_016879397.1|dip:DIP-39892N|ensembl:ENSG00000103540(gene)|ensembl:ENST00000381396(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007099"(centriole replication)|go:"GO:0032053"(ciliary basal body organization)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0051298"(centrosome duplication)|go:"GO:1902018"(negative regulation of cilium assembly)|go:"GO:1903723"(negative regulation of centriole elongation)|interpro:IPR033207|mint:O43303|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5689880|reactome:R-HSA-8854518|reactome:R-HSA-9013424 - - - figure legend:1B and C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/05/03 2016/05/03 rogid:89HbDVs4UVmzftFFLO/pHklTiUQ9606 rogid:Gvda4RoDRcY+G50iRW5T+haubps9606 rigid:Mt5EJbMSbMebEHqzvQUMv9X5pjc false flag tag:?-?|sufficient binding region:221-366|sufficient binding region:362-822 - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O15078 uniprotkb:O43303 intact:EBI-1811944|uniprotkb:Q1PSK5|uniprotkb:Q66GS8|uniprotkb:Q9H2G6|uniprotkb:Q9H6Q7|uniprotkb:Q9H8I0|ensembl:ENSP00000448012 intact:EBI-1566217|uniprotkb:O43335|uniprotkb:Q68DV9|uniprotkb:Q8NE13|uniprotkb:B7WP23|ensembl:ENSP00000370803 psi-mi:ce290_human(display_long)|uniprotkb:CEP290(gene name)|psi-mi:CEP290(display_short)|uniprotkb:KIAA0373(gene name synonym)|uniprotkb:NPHP6(gene name synonym)|uniprotkb:Nephrocystin-6(gene name synonym)|uniprotkb:Tumor antigen se2-2(gene name synonym)|uniprotkb:Cancer/testis antigen 87(gene name synonym)|uniprotkb:BBS14(gene name synonym)|uniprotkb:Bardet-Biedl syndrome 14 protein(gene name synonym) psi-mi:cp110_human(display_long)|uniprotkb:CP110(gene name synonym)|uniprotkb:CCP110(gene name)|psi-mi:CCP110(display_short)|uniprotkb:CEP110(gene name synonym)|uniprotkb:KIAA0419(gene name synonym)|uniprotkb:Centrosomal protein of 110 kDa(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Tsang et al. (2008) pubmed:18694559|imex:IM-25243 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-11692605|imex:IM-25243-16 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079390.3|dip:DIP-46541N|ensembl:ENSG00000198707(gene)|ensembl:ENST00000552810(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0030902"(hindbrain development)|go:"GO:0030916"(otic vesicle formation)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035580"(specific granule lumen)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048793"(pronephros development)|go:"GO:0060271"(cilium assembly)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0097711"(ciliary basal body-plasma membrane docking)|go:"GO:1905349"(ciliary transition zone assembly)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR026201|interpro:IPR032321|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-6798695|reactome:R-HSA-8854518 refseq:NP_001310498.1|refseq:NP_001185951.2|refseq:NP_001310499.1|refseq:NP_001310500.1|refseq:NP_001310501.1|refseq:NP_055526.4|refseq:XP_011544293.1|refseq:XP_011544294.1|refseq:XP_016879397.1|dip:DIP-39892N|ensembl:ENSG00000103540(gene)|ensembl:ENST00000381396(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007099"(centriole replication)|go:"GO:0032053"(ciliary basal body organization)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0051298"(centrosome duplication)|go:"GO:1902018"(negative regulation of cilium assembly)|go:"GO:1903723"(negative regulation of centriole elongation)|interpro:IPR033207|mint:O43303|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5689880|reactome:R-HSA-8854518|reactome:R-HSA-9013424 - - - figure legend:3A, B and C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/05/03 2016/05/03 rogid:89HbDVs4UVmzftFFLO/pHklTiUQ9606 rogid:Gvda4RoDRcY+G50iRW5T+haubps9606 rigid:Mt5EJbMSbMebEHqzvQUMv9X5pjc false - flag tag:?-?|sufficient binding region:1-223|necessary binding region:67-82 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O43303 uniprotkb:O15078 intact:EBI-1566217|uniprotkb:O43335|uniprotkb:Q68DV9|uniprotkb:Q8NE13|uniprotkb:B7WP23|ensembl:ENSP00000370803 intact:EBI-1811944|uniprotkb:Q1PSK5|uniprotkb:Q66GS8|uniprotkb:Q9H2G6|uniprotkb:Q9H6Q7|uniprotkb:Q9H8I0|ensembl:ENSP00000448012 psi-mi:cp110_human(display_long)|uniprotkb:CP110(gene name synonym)|uniprotkb:CCP110(gene name)|psi-mi:CCP110(display_short)|uniprotkb:CEP110(gene name synonym)|uniprotkb:KIAA0419(gene name synonym)|uniprotkb:Centrosomal protein of 110 kDa(gene name synonym) psi-mi:ce290_human(display_long)|uniprotkb:CEP290(gene name)|psi-mi:CEP290(display_short)|uniprotkb:KIAA0373(gene name synonym)|uniprotkb:NPHP6(gene name synonym)|uniprotkb:Nephrocystin-6(gene name synonym)|uniprotkb:Tumor antigen se2-2(gene name synonym)|uniprotkb:Cancer/testis antigen 87(gene name synonym)|uniprotkb:BBS14(gene name synonym)|uniprotkb:Bardet-Biedl syndrome 14 protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Tsang et al. (2008) pubmed:18694559|imex:IM-25243 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-11692630|imex:IM-25243-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001310498.1|refseq:NP_001185951.2|refseq:NP_001310499.1|refseq:NP_001310500.1|refseq:NP_001310501.1|refseq:NP_055526.4|refseq:XP_011544293.1|refseq:XP_011544294.1|refseq:XP_016879397.1|dip:DIP-39892N|ensembl:ENSG00000103540(gene)|ensembl:ENST00000381396(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007099"(centriole replication)|go:"GO:0032053"(ciliary basal body organization)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0051298"(centrosome duplication)|go:"GO:1902018"(negative regulation of cilium assembly)|go:"GO:1903723"(negative regulation of centriole elongation)|interpro:IPR033207|mint:O43303|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5689880|reactome:R-HSA-8854518|reactome:R-HSA-9013424 refseq:NP_079390.3|dip:DIP-46541N|ensembl:ENSG00000198707(gene)|ensembl:ENST00000552810(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0030902"(hindbrain development)|go:"GO:0030916"(otic vesicle formation)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035580"(specific granule lumen)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048793"(pronephros development)|go:"GO:0060271"(cilium assembly)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0097711"(ciliary basal body-plasma membrane docking)|go:"GO:1905349"(ciliary transition zone assembly)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR026201|interpro:IPR032321|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-6798695|reactome:R-HSA-8854518 - - - figure legend:3B|comment:CCP110 deletion construct missing aa 67-82 loses association with CEP290 but retains association with CEP97 and calmodulin|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/05/03 2016/05/03 rogid:Gvda4RoDRcY+G50iRW5T+haubps9606 rogid:89HbDVs4UVmzftFFLO/pHklTiUQ9606 rigid:vMNL2x5YtPyXhjS6zsEcFKrsf4Y false flag tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O43303 uniprotkb:P62158 intact:EBI-1566217|uniprotkb:O43335|uniprotkb:Q68DV9|uniprotkb:Q8NE13|uniprotkb:B7WP23|ensembl:ENSP00000370803 intact:EBI-397435|uniprotkb:P02593|uniprotkb:P70667|uniprotkb:P99014|uniprotkb:Q13942|uniprotkb:Q53S29|uniprotkb:Q61379|uniprotkb:Q61380|uniprotkb:Q96HK3|uniprotkb:P0DP25|uniprotkb:P0DP24|uniprotkb:P0DP23 psi-mi:cp110_human(display_long)|uniprotkb:CP110(gene name synonym)|uniprotkb:CCP110(gene name)|psi-mi:CCP110(display_short)|uniprotkb:CEP110(gene name synonym)|uniprotkb:KIAA0419(gene name synonym)|uniprotkb:Centrosomal protein of 110 kDa(gene name synonym) psi-mi:calm_human(display_long)|uniprotkb:CALM1(gene name)|psi-mi:CALM1(display_short)|uniprotkb:CALM(gene name synonym)|uniprotkb:CAM(gene name synonym)|uniprotkb:CAM1(gene name synonym)|uniprotkb:CALM2(gene name)|psi-mi:CALM2(display_short)|uniprotkb:CAMB(gene name synonym)|uniprotkb:CALM3(gene name)|psi-mi:CALM3(display_short)|uniprotkb:CAM3(gene name synonym)|uniprotkb:CAMC(gene name synonym)|uniprotkb:CAMIII(gene name synonym)|uniprotkb:CAM2(gene name synonym)|uniprotkb:CALML2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Tsang et al. (2008) pubmed:18694559|imex:IM-25243 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-11692630|imex:IM-25243-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001310498.1|refseq:NP_001185951.2|refseq:NP_001310499.1|refseq:NP_001310500.1|refseq:NP_001310501.1|refseq:NP_055526.4|refseq:XP_011544293.1|refseq:XP_011544294.1|refseq:XP_016879397.1|dip:DIP-39892N|ensembl:ENSG00000103540(gene)|ensembl:ENST00000381396(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007099"(centriole replication)|go:"GO:0032053"(ciliary basal body organization)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0051298"(centrosome duplication)|go:"GO:1902018"(negative regulation of cilium assembly)|go:"GO:1903723"(negative regulation of centriole elongation)|interpro:IPR033207|mint:O43303|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5689880|reactome:R-HSA-8854518|reactome:R-HSA-9013424 rcsb pdb:3SUI|rcsb pdb:2LGF|rcsb pdb:2LQC|rcsb pdb:2LQP|rcsb pdb:2Y4V|rcsb pdb:4JQ0|rcsb pdb:4LZX|rcsb pdb:4M1L|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|rcsb pdb:3J41|rcsb pdb:2LL6|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0030017"(sarcomere)|go:"GO:0030801"(obsolete positive regulation of cyclic nucleotide metabolic process)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0051343"(positive regulation of cyclic-nucleotide phosphodiesterase activity)|go:"GO:0072542"(protein phosphatase activator activity)|go:"GO:1901844"(regulation of cell communication by electrical coupling involved in cardiac conduction)|rcsb pdb:2LV6|rcsb pdb:2N6A|refseq:NP_001734.1|refseq:NP_005175.2|refseq:NP_008819.1|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005876"(spindle microtubule)|go:"GO:0000922"(spindle pole)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005980"(glycogen catabolic process)|go:"GO:0006936"(muscle contraction)|go:"GO:0060315"(negative regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0002576"(platelet degranulation)|go:"GO:0060316"(positive regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0050999"(regulation of nitric-oxide synthase activity)|rcsb pdb:1AJI|rcsb pdb:1CDL|rcsb pdb:1CLL|rcsb pdb:1CTR|rcsb pdb:1IWQ|rcsb pdb:1J7O|rcsb pdb:1J7P|rcsb pdb:1K90|rcsb pdb:1K93|rcsb pdb:1L7Z|rcsb pdb:1LVC|rcsb pdb:1NKF|rcsb pdb:1PK0|rcsb pdb:1S26|rcsb pdb:1SK6|rcsb pdb:1SW8|rcsb pdb:1WRZ|rcsb pdb:1XFU|rcsb pdb:1XFV|rcsb pdb:1XFW|rcsb pdb:1XFX|rcsb pdb:1XFY|rcsb pdb:1XFZ|rcsb pdb:1Y6W|rcsb pdb:1YR5|rcsb pdb:1YRT|rcsb pdb:1YRU|rcsb pdb:1ZOT|rcsb pdb:1ZUZ|rcsb pdb:2BE6|rcsb pdb:2F3Y|rcsb pdb:2F3Z|rcsb pdb:2HF5|rcsb pdb:2I08|rcsb pdb:2JZI|rcsb pdb:2K0E|rcsb pdb:2K0F|rcsb pdb:2K0J|rcsb pdb:2K61|rcsb pdb:2KNE|rcsb pdb:2KUG|rcsb pdb:2KUH|rcsb pdb:2L53|rcsb pdb:2L7L|rcsb pdb:2R28|rcsb pdb:2V01|rcsb pdb:2V02|rcsb pdb:2VAY|rcsb pdb:2W73|rcsb pdb:2WEL|rcsb pdb:2X0G|rcsb pdb:3BYA|rcsb pdb:3DVE|rcsb pdb:3DVJ|rcsb pdb:3DVK|rcsb pdb:3DVM|rcsb pdb:3EWT|rcsb pdb:3EWV|rcsb pdb:3G43|rcsb pdb:3HR4|rcsb pdb:3O77|rcsb pdb:3O78|rcsb pdb:3OXQ|rcsb pdb:3UCT|rcsb pdb:3UCW|rcsb pdb:3UCY|rcsb pdb:4DCK|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0000165"(MAPK cascade)|rcsb pdb:2M0J|rcsb pdb:2M0K|rcsb pdb:4UMO|rcsb pdb:4V0C|go:"GO:0031982"(vesicle)|rcsb pdb:4Q5U|rcsb pdb:4UPU|reactome:R-HSA-2672351|reactome:R-HSA-418359|reactome:R-HSA-425561|reactome:R-HSA-5576892|reactome:R-HSA-5578775|reactome:R-HSA-936837|refseq:NP_001292555.1|rcsb pdb:4OVN|rcsb pdb:5COC|go:"GO:0021762"(substantia nigra development)|go:"GO:0070062"(extracellular exosome)|rcsb pdb:4BW7|rcsb pdb:4BW8|rcsb pdb:4L79|rcsb pdb:5DBR|rcsb pdb:4DJC|rcsb pdb:2M55|rcsb pdb:2LL7|go:"GO:0019855"(calcium channel inhibitor activity)|go:"GO:0001975"(response to amphetamine)|go:"GO:0007190"(activation of adenylate cyclase activity)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030426"(growth cone)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051412"(response to corticosterone)|go:"GO:1901841"(regulation of high voltage-gated calcium channel activity)|rcsb pdb:2N77|go:"GO:0032991"(protein-containing complex)|go:"GO:0006479"(protein methylation)|go:"GO:0014069"(postsynaptic density)|rcsb pdb:5DSU|reactome:R-HSA-8876725|rcsb pdb:4GOW|rcsb pdb:4Q57|go:"GO:0043647"(inositol phosphate metabolic process)|go:"GO:0022400"(regulation of rhodopsin mediated signaling pathway)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031432"(titin binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0031997"(N-terminal myristoylation domain binding)|go:"GO:0043274"(phospholipase binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055117"(regulation of cardiac muscle contraction)|rcsb pdb:2MG5|go:"GO:0005088"|go:"GO:0007223"(Wnt signaling pathway, calcium modulating pathway)|go:"GO:0008440"(inositol-1,4,5-trisphosphate 3-kinase activity)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0005634"(nucleus)|rcsb pdb:4JPZ|ensembl:ENST00000272298|ensembl:ENST00000291295|ensembl:ENST00000356978|ensembl:ENST00000596362|refseq:NP_001292553.1|refseq:NP_001292554.1|rcsb pdb:4BYF|reactome:R-HSA-111932|reactome:R-HSA-111933|reactome:R-HSA-111957|reactome:R-HSA-111997|reactome:R-HSA-114608|reactome:R-HSA-1445148|reactome:R-HSA-1474151|reactome:R-HSA-180024|reactome:R-HSA-1855204|reactome:R-HSA-203615|reactome:R-HSA-2514859|reactome:R-HSA-2871809|reactome:R-HSA-4086398|reactome:R-HSA-442717|reactome:R-HSA-442729|reactome:R-HSA-442745|reactome:R-HSA-442982|reactome:R-HSA-445355|reactome:R-HSA-451308|reactome:R-HSA-5218920|reactome:R-HSA-5218921|reactome:R-HSA-5607763|reactome:R-HSA-5626467|reactome:R-HSA-5627123|reactome:R-HSA-5673001|reactome:R-HSA-70221|reactome:R-HSA-983695|ensembl:ENSG00000143933|ensembl:ENSG00000160014|ensembl:ENSG00000198668|ensembl:ENSP00000272298|ensembl:ENSP00000291295|ensembl:ENSP00000349467|ensembl:ENSP00000472141|rcsb pdb:5NIN|rcsb pdb:5VMS|rcsb pdb:5WSU|rcsb pdb:5WSV|rcsb pdb:6U39|rcsb pdb:6U3A|rcsb pdb:6U3B|rcsb pdb:6U3D|rcsb pdb:2N8J|rcsb pdb:5GGM|rcsb pdb:5J8H|reactome:R-HSA-163615|reactome:R-HSA-5210891|refseq:NP_001316851.1|refseq:NP_001316852.1|refseq:NP_001316853.1|refseq:NP_001316854.1|refseq:NP_001316855.1|rcsb pdb:2N27|rcsb pdb:5DOW|rcsb pdb:5I0I|rcsb pdb:5J03|rcsb pdb:5K7L|rcsb pdb:5K8Q|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0043388"(positive regulation of DNA binding)|dip:DIP-31794N|rcsb pdb:1UP5|rcsb pdb:5JQA|rcsb pdb:5JTH|rcsb pdb:5OEO|rcsb pdb:5TP5|rcsb pdb:5TP6|rcsb pdb:5V02|rcsb pdb:5V03|rcsb pdb:5V7X|rcsb pdb:5WBX|rcsb pdb:5WC5|rcsb pdb:6B8L|rcsb pdb:6B8M|rcsb pdb:6B8N|rcsb pdb:6B8P|rcsb pdb:6B8Q|rcsb pdb:6C1D|rcsb pdb:6C1G|rcsb pdb:6C1H|rcsb pdb:6CNM|rcsb pdb:6CNN|rcsb pdb:6CNO|rcsb pdb:6FEG|rcsb pdb:6FEH|reactome:R-HSA-2025928|reactome:R-HSA-2151201|go:"GO:0034704"(calcium channel complex)|go:"GO:0010856"(adenylate cyclase activator activity)|go:"GO:0051186"(obsolete cofactor metabolic process)|go:"GO:0075206"(obsolete positive regulation by host of symbiont cAMP-mediated signal transduction)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|interpro:IPR039030|go:"GO:1902494"(catalytic complex)|go:"GO:0043234"|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0030819"(obsolete positive regulation of cAMP biosynthetic process)|rcsb pdb:6BUT|rcsb pdb:6DAD|rcsb pdb:6DAE|rcsb pdb:6DAF|rcsb pdb:6DAH|rcsb pdb:6E2F|rcsb pdb:6E2G|rcsb pdb:6EEB|rcsb pdb:6GDK|rcsb pdb:6GDL|rcsb pdb:6HCS|rcsb pdb:6JI8|rcsb pdb:6JII|rcsb pdb:6JIU|rcsb pdb:6JIY|rcsb pdb:6JRS|rcsb pdb:6JV2|rcsb pdb:6K4K|rcsb pdb:6K4L|rcsb pdb:6K4R|rcsb pdb:6MUD|rcsb pdb:6MUE|rcsb pdb:6N5W|rcsb pdb:6O5G|reactome:R-HSA-438066|reactome:R-HSA-442720|reactome:R-HSA-5673000|reactome:R-HSA-6802946|reactome:R-HSA-6802949|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9009391|reactome:R-HSA-9022535|reactome:R-HSA-9022692|reactome:R-HSA-9617324|reactome:R-HSA-9619229|reactome:R-HSA-9619483|reactome:R-HSA-9620244|go:"GO:0019722"(calcium-mediated signaling)|rcsb pdb:6PBX|rcsb pdb:6PBY|reactome:R-HSA-9649948|go:"GO:0005623"(obsolete cell)|rcsb pdb:6HR1|rcsb pdb:6OS4|rcsb pdb:6Y4P|rcsb pdb:6Y94|rcsb pdb:6Y95|reactome:R-HSA-9664323|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0016032"(viral process)|rcsb pdb:6M7H|rcsb pdb:6UZZ|rcsb pdb:6V00|rcsb pdb:6V01|rcsb pdb:6PLM|rcsb pdb:6S5T|rcsb pdb:6SZ5|rcsb pdb:6XXF|rcsb pdb:6Y4O - - - figure legend:3B|comment:CCP110 deletion construct missing aa 67-82 loses association with CEP290 but retains association with CEP97 and calmodulin|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/05/03 2016/05/03 rogid:Gvda4RoDRcY+G50iRW5T+haubps9606 rogid:tTYcOd9bOh211njZVz7cYVybAMQ9606 rigid:vMNL2x5YtPyXhjS6zsEcFKrsf4Y false flag tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O43303 uniprotkb:Q8IW35 intact:EBI-1566217|uniprotkb:O43335|uniprotkb:Q68DV9|uniprotkb:Q8NE13|uniprotkb:B7WP23|ensembl:ENSP00000370803 intact:EBI-1566210|uniprotkb:Q8NA71|uniprotkb:Q9H5T9|uniprotkb:B5MDY8|intact:EBI-2560935|ensembl:ENSP00000342510 psi-mi:cp110_human(display_long)|uniprotkb:CP110(gene name synonym)|uniprotkb:CCP110(gene name)|psi-mi:CCP110(display_short)|uniprotkb:CEP110(gene name synonym)|uniprotkb:KIAA0419(gene name synonym)|uniprotkb:Centrosomal protein of 110 kDa(gene name synonym) psi-mi:cep97_human(display_long)|uniprotkb:LRRIQ2(gene name synonym)|uniprotkb:Leucine-rich repeat and IQ domain-containing protein 2(gene name synonym)|uniprotkb:CEP97(gene name)|psi-mi:CEP97(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Tsang et al. (2008) pubmed:18694559|imex:IM-25243 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-11692630|imex:IM-25243-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001310498.1|refseq:NP_001185951.2|refseq:NP_001310499.1|refseq:NP_001310500.1|refseq:NP_001310501.1|refseq:NP_055526.4|refseq:XP_011544293.1|refseq:XP_011544294.1|refseq:XP_016879397.1|dip:DIP-39892N|ensembl:ENSG00000103540(gene)|ensembl:ENST00000381396(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007099"(centriole replication)|go:"GO:0032053"(ciliary basal body organization)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0051298"(centrosome duplication)|go:"GO:1902018"(negative regulation of cilium assembly)|go:"GO:1903723"(negative regulation of centriole elongation)|interpro:IPR033207|mint:O43303|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5689880|reactome:R-HSA-8854518|reactome:R-HSA-9013424 refseq:NP_078824.2|refseq:NP_001290330.1|ensembl:ENSG00000182504(gene)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0030030"(cell projection organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:1901673"(regulation of mitotic spindle assembly)|go:"GO:1902018"(negative regulation of cilium assembly)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR032675|mint:Q8IW35|reactome:R-HSA-5620912|reactome:R-HSA-9013424|ensembl:ENST00000341893(transcript) - - - figure legend:3B|comment:CCP110 deletion construct missing aa 67-82 loses association with CEP290 but retains association with CEP97 and calmodulin|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/05/03 2016/05/03 rogid:Gvda4RoDRcY+G50iRW5T+haubps9606 rogid:Gz4rQbzgNiEg1X01O7YWz4TmfQA9606 rigid:vMNL2x5YtPyXhjS6zsEcFKrsf4Y false flag tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O15078 uniprotkb:P61006 intact:EBI-1811944|uniprotkb:Q1PSK5|uniprotkb:Q66GS8|uniprotkb:Q9H2G6|uniprotkb:Q9H6Q7|uniprotkb:Q9H8I0|ensembl:ENSP00000448012 intact:EBI-722293|intact:EBI-1054454|uniprotkb:P24407|intact:EBI-2798283|uniprotkb:Q6FHV5|uniprotkb:B4DEK7|ensembl:ENSP00000300935 psi-mi:ce290_human(display_long)|uniprotkb:CEP290(gene name)|psi-mi:CEP290(display_short)|uniprotkb:KIAA0373(gene name synonym)|uniprotkb:NPHP6(gene name synonym)|uniprotkb:Nephrocystin-6(gene name synonym)|uniprotkb:Tumor antigen se2-2(gene name synonym)|uniprotkb:Cancer/testis antigen 87(gene name synonym)|uniprotkb:BBS14(gene name synonym)|uniprotkb:Bardet-Biedl syndrome 14 protein(gene name synonym) psi-mi:rab8a_human(display_long)|uniprotkb:Oncogene c-mel(gene name synonym)|uniprotkb:RAB8A(gene name)|psi-mi:RAB8A(display_short)|uniprotkb:MEL(gene name synonym)|uniprotkb:RAB8(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Tsang et al. (2008) pubmed:18694559|imex:IM-25243 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-11692790|imex:IM-25243-21 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079390.3|dip:DIP-46541N|ensembl:ENSG00000198707(gene)|ensembl:ENST00000552810(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0030902"(hindbrain development)|go:"GO:0030916"(otic vesicle formation)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035580"(specific granule lumen)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048793"(pronephros development)|go:"GO:0060271"(cilium assembly)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0097711"(ciliary basal body-plasma membrane docking)|go:"GO:1905349"(ciliary transition zone assembly)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR026201|interpro:IPR032321|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-6798695|reactome:R-HSA-8854518 refseq:NP_005361.2|dip:DIP-43703N|ensembl:ENSG00000167461(gene)|ensembl:ENST00000300935(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0007409"(axonogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0009306"(protein secretion)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0019003"(GDP binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0030496"(midbody)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031489"(myosin V binding)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0048210"(Golgi vesicle fusion to target membrane)|go:"GO:0051223"(regulation of protein transport)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097730"(non-motile cilium)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098969"(neurotransmitter receptor transport to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099003"(vesicle-mediated transport in synapse)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P61006|rcsb pdb:3QBT|rcsb pdb:3TNF|rcsb pdb:4LHV|rcsb pdb:4LHW|rcsb pdb:4LHX|rcsb pdb:4LHY|go:"GO:0014069"(postsynaptic density)|go:"GO:0017157"(regulation of exocytosis)|rcsb pdb:4LHZ|rcsb pdb:4LI0|rcsb pdb:5SZI|rcsb pdb:6RIR|rcsb pdb:6SQ2|rcsb pdb:6STF|rcsb pdb:6STG|rcsb pdb:6WHE|rcsb pdb:6ZSI|rcsb pdb:6ZSJ|rcsb pdb:7BWT|rcsb pdb:7LWB|reactome:R-HSA-1445148|reactome:R-HSA-2565942|reactome:R-HSA-5620912|reactome:R-HSA-5620916|reactome:R-HSA-8854214|reactome:R-HSA-8873719|reactome:R-HSA-8876198 - - - figure legend:6A and B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/05/03 2016/05/04 rogid:89HbDVs4UVmzftFFLO/pHklTiUQ9606 rogid:ucWVK9e1z44F2XnAJatPYm8IRlk9606 rigid:SFYzOlIU4TA6g6EktmTR0GCusFI false flag tag:?-?|sufficient binding region:580-1695 - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q12798 uniprotkb:O43303 intact:EBI-2512818|ensembl:ENSP00000319052|uniprotkb:B2R536 intact:EBI-1566217|uniprotkb:O43335|uniprotkb:Q68DV9|uniprotkb:Q8NE13|uniprotkb:B7WP23|ensembl:ENSP00000370803 psi-mi:cetn1_human(display_long)|uniprotkb:CETN1(gene name)|psi-mi:CETN1(display_short)|uniprotkb:CEN1(gene name synonym)|uniprotkb:CETN(gene name synonym)|uniprotkb:Caltractin isoform 2(gene name synonym) psi-mi:cp110_human(display_long)|uniprotkb:CP110(gene name synonym)|uniprotkb:CCP110(gene name)|psi-mi:CCP110(display_short)|uniprotkb:CEP110(gene name synonym)|uniprotkb:KIAA0419(gene name synonym)|uniprotkb:Centrosomal protein of 110 kDa(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Tsang et al. (2008) pubmed:18694559|imex:IM-25243 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-11692538|imex:IM-25243-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000177143(gene)|ensembl:ENST00000327228(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0007099"(centriole replication)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0051301"(cell division)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR029527|reactome:R-HSA-9613829|reactome:R-HSA-9615710|reactome:R-HSA-9646399|refseq:NP_004057.1 refseq:NP_001310498.1|refseq:NP_001185951.2|refseq:NP_001310499.1|refseq:NP_001310500.1|refseq:NP_001310501.1|refseq:NP_055526.4|refseq:XP_011544293.1|refseq:XP_011544294.1|refseq:XP_016879397.1|dip:DIP-39892N|ensembl:ENSG00000103540(gene)|ensembl:ENST00000381396(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007099"(centriole replication)|go:"GO:0032053"(ciliary basal body organization)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0051298"(centrosome duplication)|go:"GO:1902018"(negative regulation of cilium assembly)|go:"GO:1903723"(negative regulation of centriole elongation)|interpro:IPR033207|mint:O43303|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5689880|reactome:R-HSA-8854518|reactome:R-HSA-9013424 - - - figure legend:1D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/05/03 2016/05/03 rogid:uZs9mMo7OXGTDDaadTQGyV/v0iM9606 rogid:Gvda4RoDRcY+G50iRW5T+haubps9606 rigid:ivabodUf6FWmia0CXL9p2THXV6w false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q12798 uniprotkb:P62158 intact:EBI-2512818|ensembl:ENSP00000319052|uniprotkb:B2R536 intact:EBI-397435|uniprotkb:P02593|uniprotkb:P70667|uniprotkb:P99014|uniprotkb:Q13942|uniprotkb:Q53S29|uniprotkb:Q61379|uniprotkb:Q61380|uniprotkb:Q96HK3|uniprotkb:P0DP25|uniprotkb:P0DP24|uniprotkb:P0DP23 psi-mi:cetn1_human(display_long)|uniprotkb:CETN1(gene name)|psi-mi:CETN1(display_short)|uniprotkb:CEN1(gene name synonym)|uniprotkb:CETN(gene name synonym)|uniprotkb:Caltractin isoform 2(gene name synonym) psi-mi:calm_human(display_long)|uniprotkb:CALM1(gene name)|psi-mi:CALM1(display_short)|uniprotkb:CALM(gene name synonym)|uniprotkb:CAM(gene name synonym)|uniprotkb:CAM1(gene name synonym)|uniprotkb:CALM2(gene name)|psi-mi:CALM2(display_short)|uniprotkb:CAMB(gene name synonym)|uniprotkb:CALM3(gene name)|psi-mi:CALM3(display_short)|uniprotkb:CAM3(gene name synonym)|uniprotkb:CAMC(gene name synonym)|uniprotkb:CAMIII(gene name synonym)|uniprotkb:CAM2(gene name synonym)|uniprotkb:CALML2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Tsang et al. (2008) pubmed:18694559|imex:IM-25243 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-11692538|imex:IM-25243-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000177143(gene)|ensembl:ENST00000327228(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0007099"(centriole replication)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0051301"(cell division)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR029527|reactome:R-HSA-9613829|reactome:R-HSA-9615710|reactome:R-HSA-9646399|refseq:NP_004057.1 rcsb pdb:3SUI|rcsb pdb:2LGF|rcsb pdb:2LQC|rcsb pdb:2LQP|rcsb pdb:2Y4V|rcsb pdb:4JQ0|rcsb pdb:4LZX|rcsb pdb:4M1L|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|rcsb pdb:3J41|rcsb pdb:2LL6|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0030017"(sarcomere)|go:"GO:0030801"(obsolete positive regulation of cyclic nucleotide metabolic process)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0051343"(positive regulation of cyclic-nucleotide phosphodiesterase activity)|go:"GO:0072542"(protein phosphatase activator activity)|go:"GO:1901844"(regulation of cell communication by electrical coupling involved in cardiac conduction)|rcsb pdb:2LV6|rcsb pdb:2N6A|refseq:NP_001734.1|refseq:NP_005175.2|refseq:NP_008819.1|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005876"(spindle microtubule)|go:"GO:0000922"(spindle pole)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005980"(glycogen catabolic process)|go:"GO:0006936"(muscle contraction)|go:"GO:0060315"(negative regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0002576"(platelet degranulation)|go:"GO:0060316"(positive regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0050999"(regulation of nitric-oxide synthase activity)|rcsb pdb:1AJI|rcsb pdb:1CDL|rcsb pdb:1CLL|rcsb pdb:1CTR|rcsb pdb:1IWQ|rcsb pdb:1J7O|rcsb pdb:1J7P|rcsb pdb:1K90|rcsb pdb:1K93|rcsb pdb:1L7Z|rcsb pdb:1LVC|rcsb pdb:1NKF|rcsb pdb:1PK0|rcsb pdb:1S26|rcsb pdb:1SK6|rcsb pdb:1SW8|rcsb pdb:1WRZ|rcsb pdb:1XFU|rcsb pdb:1XFV|rcsb pdb:1XFW|rcsb pdb:1XFX|rcsb pdb:1XFY|rcsb pdb:1XFZ|rcsb pdb:1Y6W|rcsb pdb:1YR5|rcsb pdb:1YRT|rcsb pdb:1YRU|rcsb pdb:1ZOT|rcsb pdb:1ZUZ|rcsb pdb:2BE6|rcsb pdb:2F3Y|rcsb pdb:2F3Z|rcsb pdb:2HF5|rcsb pdb:2I08|rcsb pdb:2JZI|rcsb pdb:2K0E|rcsb pdb:2K0F|rcsb pdb:2K0J|rcsb pdb:2K61|rcsb pdb:2KNE|rcsb pdb:2KUG|rcsb pdb:2KUH|rcsb pdb:2L53|rcsb pdb:2L7L|rcsb pdb:2R28|rcsb pdb:2V01|rcsb pdb:2V02|rcsb pdb:2VAY|rcsb pdb:2W73|rcsb pdb:2WEL|rcsb pdb:2X0G|rcsb pdb:3BYA|rcsb pdb:3DVE|rcsb pdb:3DVJ|rcsb pdb:3DVK|rcsb pdb:3DVM|rcsb pdb:3EWT|rcsb pdb:3EWV|rcsb pdb:3G43|rcsb pdb:3HR4|rcsb pdb:3O77|rcsb pdb:3O78|rcsb pdb:3OXQ|rcsb pdb:3UCT|rcsb pdb:3UCW|rcsb pdb:3UCY|rcsb pdb:4DCK|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0000165"(MAPK cascade)|rcsb pdb:2M0J|rcsb pdb:2M0K|rcsb pdb:4UMO|rcsb pdb:4V0C|go:"GO:0031982"(vesicle)|rcsb pdb:4Q5U|rcsb pdb:4UPU|reactome:R-HSA-2672351|reactome:R-HSA-418359|reactome:R-HSA-425561|reactome:R-HSA-5576892|reactome:R-HSA-5578775|reactome:R-HSA-936837|refseq:NP_001292555.1|rcsb pdb:4OVN|rcsb pdb:5COC|go:"GO:0021762"(substantia nigra development)|go:"GO:0070062"(extracellular exosome)|rcsb pdb:4BW7|rcsb pdb:4BW8|rcsb pdb:4L79|rcsb pdb:5DBR|rcsb pdb:4DJC|rcsb pdb:2M55|rcsb pdb:2LL7|go:"GO:0019855"(calcium channel inhibitor activity)|go:"GO:0001975"(response to amphetamine)|go:"GO:0007190"(activation of adenylate cyclase activity)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030426"(growth cone)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051412"(response to corticosterone)|go:"GO:1901841"(regulation of high voltage-gated calcium channel activity)|rcsb pdb:2N77|go:"GO:0032991"(protein-containing complex)|go:"GO:0006479"(protein methylation)|go:"GO:0014069"(postsynaptic density)|rcsb pdb:5DSU|reactome:R-HSA-8876725|rcsb pdb:4GOW|rcsb pdb:4Q57|go:"GO:0043647"(inositol phosphate metabolic process)|go:"GO:0022400"(regulation of rhodopsin mediated signaling pathway)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031432"(titin binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0031997"(N-terminal myristoylation domain binding)|go:"GO:0043274"(phospholipase binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055117"(regulation of cardiac muscle contraction)|rcsb pdb:2MG5|go:"GO:0005088"|go:"GO:0007223"(Wnt signaling pathway, calcium modulating pathway)|go:"GO:0008440"(inositol-1,4,5-trisphosphate 3-kinase activity)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0005634"(nucleus)|rcsb pdb:4JPZ|ensembl:ENST00000272298|ensembl:ENST00000291295|ensembl:ENST00000356978|ensembl:ENST00000596362|refseq:NP_001292553.1|refseq:NP_001292554.1|rcsb pdb:4BYF|reactome:R-HSA-111932|reactome:R-HSA-111933|reactome:R-HSA-111957|reactome:R-HSA-111997|reactome:R-HSA-114608|reactome:R-HSA-1445148|reactome:R-HSA-1474151|reactome:R-HSA-180024|reactome:R-HSA-1855204|reactome:R-HSA-203615|reactome:R-HSA-2514859|reactome:R-HSA-2871809|reactome:R-HSA-4086398|reactome:R-HSA-442717|reactome:R-HSA-442729|reactome:R-HSA-442745|reactome:R-HSA-442982|reactome:R-HSA-445355|reactome:R-HSA-451308|reactome:R-HSA-5218920|reactome:R-HSA-5218921|reactome:R-HSA-5607763|reactome:R-HSA-5626467|reactome:R-HSA-5627123|reactome:R-HSA-5673001|reactome:R-HSA-70221|reactome:R-HSA-983695|ensembl:ENSG00000143933|ensembl:ENSG00000160014|ensembl:ENSG00000198668|ensembl:ENSP00000272298|ensembl:ENSP00000291295|ensembl:ENSP00000349467|ensembl:ENSP00000472141|rcsb pdb:5NIN|rcsb pdb:5VMS|rcsb pdb:5WSU|rcsb pdb:5WSV|rcsb pdb:6U39|rcsb pdb:6U3A|rcsb pdb:6U3B|rcsb pdb:6U3D|rcsb pdb:2N8J|rcsb pdb:5GGM|rcsb pdb:5J8H|reactome:R-HSA-163615|reactome:R-HSA-5210891|refseq:NP_001316851.1|refseq:NP_001316852.1|refseq:NP_001316853.1|refseq:NP_001316854.1|refseq:NP_001316855.1|rcsb pdb:2N27|rcsb pdb:5DOW|rcsb pdb:5I0I|rcsb pdb:5J03|rcsb pdb:5K7L|rcsb pdb:5K8Q|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0043388"(positive regulation of DNA binding)|dip:DIP-31794N|rcsb pdb:1UP5|rcsb pdb:5JQA|rcsb pdb:5JTH|rcsb pdb:5OEO|rcsb pdb:5TP5|rcsb pdb:5TP6|rcsb pdb:5V02|rcsb pdb:5V03|rcsb pdb:5V7X|rcsb pdb:5WBX|rcsb pdb:5WC5|rcsb pdb:6B8L|rcsb pdb:6B8M|rcsb pdb:6B8N|rcsb pdb:6B8P|rcsb pdb:6B8Q|rcsb pdb:6C1D|rcsb pdb:6C1G|rcsb pdb:6C1H|rcsb pdb:6CNM|rcsb pdb:6CNN|rcsb pdb:6CNO|rcsb pdb:6FEG|rcsb pdb:6FEH|reactome:R-HSA-2025928|reactome:R-HSA-2151201|go:"GO:0034704"(calcium channel complex)|go:"GO:0010856"(adenylate cyclase activator activity)|go:"GO:0051186"(obsolete cofactor metabolic process)|go:"GO:0075206"(obsolete positive regulation by host of symbiont cAMP-mediated signal transduction)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|interpro:IPR039030|go:"GO:1902494"(catalytic complex)|go:"GO:0043234"|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0030819"(obsolete positive regulation of cAMP biosynthetic process)|rcsb pdb:6BUT|rcsb pdb:6DAD|rcsb pdb:6DAE|rcsb pdb:6DAF|rcsb pdb:6DAH|rcsb pdb:6E2F|rcsb pdb:6E2G|rcsb pdb:6EEB|rcsb pdb:6GDK|rcsb pdb:6GDL|rcsb pdb:6HCS|rcsb pdb:6JI8|rcsb pdb:6JII|rcsb pdb:6JIU|rcsb pdb:6JIY|rcsb pdb:6JRS|rcsb pdb:6JV2|rcsb pdb:6K4K|rcsb pdb:6K4L|rcsb pdb:6K4R|rcsb pdb:6MUD|rcsb pdb:6MUE|rcsb pdb:6N5W|rcsb pdb:6O5G|reactome:R-HSA-438066|reactome:R-HSA-442720|reactome:R-HSA-5673000|reactome:R-HSA-6802946|reactome:R-HSA-6802949|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9009391|reactome:R-HSA-9022535|reactome:R-HSA-9022692|reactome:R-HSA-9617324|reactome:R-HSA-9619229|reactome:R-HSA-9619483|reactome:R-HSA-9620244|go:"GO:0019722"(calcium-mediated signaling)|rcsb pdb:6PBX|rcsb pdb:6PBY|reactome:R-HSA-9649948|go:"GO:0005623"(obsolete cell)|rcsb pdb:6HR1|rcsb pdb:6OS4|rcsb pdb:6Y4P|rcsb pdb:6Y94|rcsb pdb:6Y95|reactome:R-HSA-9664323|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0016032"(viral process)|rcsb pdb:6M7H|rcsb pdb:6UZZ|rcsb pdb:6V00|rcsb pdb:6V01|rcsb pdb:6PLM|rcsb pdb:6S5T|rcsb pdb:6SZ5|rcsb pdb:6XXF|rcsb pdb:6Y4O - - - figure legend:1D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/05/03 2016/05/03 rogid:uZs9mMo7OXGTDDaadTQGyV/v0iM9606 rogid:tTYcOd9bOh211njZVz7cYVybAMQ9606 rigid:ivabodUf6FWmia0CXL9p2THXV6w false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8IW35 uniprotkb:O43303 intact:EBI-1566210|uniprotkb:Q8NA71|uniprotkb:Q9H5T9|uniprotkb:B5MDY8|intact:EBI-2560935|ensembl:ENSP00000342510 intact:EBI-1566217|uniprotkb:O43335|uniprotkb:Q68DV9|uniprotkb:Q8NE13|uniprotkb:B7WP23|ensembl:ENSP00000370803 psi-mi:cep97_human(display_long)|uniprotkb:LRRIQ2(gene name synonym)|uniprotkb:Leucine-rich repeat and IQ domain-containing protein 2(gene name synonym)|uniprotkb:CEP97(gene name)|psi-mi:CEP97(display_short) psi-mi:cp110_human(display_long)|uniprotkb:CP110(gene name synonym)|uniprotkb:CCP110(gene name)|psi-mi:CCP110(display_short)|uniprotkb:CEP110(gene name synonym)|uniprotkb:KIAA0419(gene name synonym)|uniprotkb:Centrosomal protein of 110 kDa(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Tsang et al. (2008) pubmed:18694559|imex:IM-25243 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-11692543|imex:IM-25243-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_078824.2|refseq:NP_001290330.1|ensembl:ENSG00000182504(gene)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0030030"(cell projection organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:1901673"(regulation of mitotic spindle assembly)|go:"GO:1902018"(negative regulation of cilium assembly)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR032675|mint:Q8IW35|reactome:R-HSA-5620912|reactome:R-HSA-9013424|ensembl:ENST00000341893(transcript) refseq:NP_001310498.1|refseq:NP_001185951.2|refseq:NP_001310499.1|refseq:NP_001310500.1|refseq:NP_001310501.1|refseq:NP_055526.4|refseq:XP_011544293.1|refseq:XP_011544294.1|refseq:XP_016879397.1|dip:DIP-39892N|ensembl:ENSG00000103540(gene)|ensembl:ENST00000381396(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007099"(centriole replication)|go:"GO:0032053"(ciliary basal body organization)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0051298"(centrosome duplication)|go:"GO:1902018"(negative regulation of cilium assembly)|go:"GO:1903723"(negative regulation of centriole elongation)|interpro:IPR033207|mint:O43303|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5689880|reactome:R-HSA-8854518|reactome:R-HSA-9013424 - - - figure legend:1D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/05/03 2016/05/03 rogid:Gz4rQbzgNiEg1X01O7YWz4TmfQA9606 rogid:Gvda4RoDRcY+G50iRW5T+haubps9606 rigid:ekoxyVMDm9vR+aM9/XU2I3BYa+U false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8IW35 uniprotkb:P62158 intact:EBI-1566210|uniprotkb:Q8NA71|uniprotkb:Q9H5T9|uniprotkb:B5MDY8|intact:EBI-2560935|ensembl:ENSP00000342510 intact:EBI-397435|uniprotkb:P02593|uniprotkb:P70667|uniprotkb:P99014|uniprotkb:Q13942|uniprotkb:Q53S29|uniprotkb:Q61379|uniprotkb:Q61380|uniprotkb:Q96HK3|uniprotkb:P0DP25|uniprotkb:P0DP24|uniprotkb:P0DP23 psi-mi:cep97_human(display_long)|uniprotkb:LRRIQ2(gene name synonym)|uniprotkb:Leucine-rich repeat and IQ domain-containing protein 2(gene name synonym)|uniprotkb:CEP97(gene name)|psi-mi:CEP97(display_short) psi-mi:calm_human(display_long)|uniprotkb:CALM1(gene name)|psi-mi:CALM1(display_short)|uniprotkb:CALM(gene name synonym)|uniprotkb:CAM(gene name synonym)|uniprotkb:CAM1(gene name synonym)|uniprotkb:CALM2(gene name)|psi-mi:CALM2(display_short)|uniprotkb:CAMB(gene name synonym)|uniprotkb:CALM3(gene name)|psi-mi:CALM3(display_short)|uniprotkb:CAM3(gene name synonym)|uniprotkb:CAMC(gene name synonym)|uniprotkb:CAMIII(gene name synonym)|uniprotkb:CAM2(gene name synonym)|uniprotkb:CALML2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Tsang et al. (2008) pubmed:18694559|imex:IM-25243 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-11692543|imex:IM-25243-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_078824.2|refseq:NP_001290330.1|ensembl:ENSG00000182504(gene)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0030030"(cell projection organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:1901673"(regulation of mitotic spindle assembly)|go:"GO:1902018"(negative regulation of cilium assembly)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR032675|mint:Q8IW35|reactome:R-HSA-5620912|reactome:R-HSA-9013424|ensembl:ENST00000341893(transcript) rcsb pdb:3SUI|rcsb pdb:2LGF|rcsb pdb:2LQC|rcsb pdb:2LQP|rcsb pdb:2Y4V|rcsb pdb:4JQ0|rcsb pdb:4LZX|rcsb pdb:4M1L|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|rcsb pdb:3J41|rcsb pdb:2LL6|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0030017"(sarcomere)|go:"GO:0030801"(obsolete positive regulation of cyclic nucleotide metabolic process)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0051343"(positive regulation of cyclic-nucleotide phosphodiesterase activity)|go:"GO:0072542"(protein phosphatase activator activity)|go:"GO:1901844"(regulation of cell communication by electrical coupling involved in cardiac conduction)|rcsb pdb:2LV6|rcsb pdb:2N6A|refseq:NP_001734.1|refseq:NP_005175.2|refseq:NP_008819.1|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005876"(spindle microtubule)|go:"GO:0000922"(spindle pole)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005980"(glycogen catabolic process)|go:"GO:0006936"(muscle contraction)|go:"GO:0060315"(negative regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0002576"(platelet degranulation)|go:"GO:0060316"(positive regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0050999"(regulation of nitric-oxide synthase activity)|rcsb pdb:1AJI|rcsb pdb:1CDL|rcsb pdb:1CLL|rcsb pdb:1CTR|rcsb pdb:1IWQ|rcsb pdb:1J7O|rcsb pdb:1J7P|rcsb pdb:1K90|rcsb pdb:1K93|rcsb pdb:1L7Z|rcsb pdb:1LVC|rcsb pdb:1NKF|rcsb pdb:1PK0|rcsb pdb:1S26|rcsb pdb:1SK6|rcsb pdb:1SW8|rcsb pdb:1WRZ|rcsb pdb:1XFU|rcsb pdb:1XFV|rcsb pdb:1XFW|rcsb pdb:1XFX|rcsb pdb:1XFY|rcsb pdb:1XFZ|rcsb pdb:1Y6W|rcsb pdb:1YR5|rcsb pdb:1YRT|rcsb pdb:1YRU|rcsb pdb:1ZOT|rcsb pdb:1ZUZ|rcsb pdb:2BE6|rcsb pdb:2F3Y|rcsb pdb:2F3Z|rcsb pdb:2HF5|rcsb pdb:2I08|rcsb pdb:2JZI|rcsb pdb:2K0E|rcsb pdb:2K0F|rcsb pdb:2K0J|rcsb pdb:2K61|rcsb pdb:2KNE|rcsb pdb:2KUG|rcsb pdb:2KUH|rcsb pdb:2L53|rcsb pdb:2L7L|rcsb pdb:2R28|rcsb pdb:2V01|rcsb pdb:2V02|rcsb pdb:2VAY|rcsb pdb:2W73|rcsb pdb:2WEL|rcsb pdb:2X0G|rcsb pdb:3BYA|rcsb pdb:3DVE|rcsb pdb:3DVJ|rcsb pdb:3DVK|rcsb pdb:3DVM|rcsb pdb:3EWT|rcsb pdb:3EWV|rcsb pdb:3G43|rcsb pdb:3HR4|rcsb pdb:3O77|rcsb pdb:3O78|rcsb pdb:3OXQ|rcsb pdb:3UCT|rcsb pdb:3UCW|rcsb pdb:3UCY|rcsb pdb:4DCK|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0000165"(MAPK cascade)|rcsb pdb:2M0J|rcsb pdb:2M0K|rcsb pdb:4UMO|rcsb pdb:4V0C|go:"GO:0031982"(vesicle)|rcsb pdb:4Q5U|rcsb pdb:4UPU|reactome:R-HSA-2672351|reactome:R-HSA-418359|reactome:R-HSA-425561|reactome:R-HSA-5576892|reactome:R-HSA-5578775|reactome:R-HSA-936837|refseq:NP_001292555.1|rcsb pdb:4OVN|rcsb pdb:5COC|go:"GO:0021762"(substantia nigra development)|go:"GO:0070062"(extracellular exosome)|rcsb pdb:4BW7|rcsb pdb:4BW8|rcsb pdb:4L79|rcsb pdb:5DBR|rcsb pdb:4DJC|rcsb pdb:2M55|rcsb pdb:2LL7|go:"GO:0019855"(calcium channel inhibitor activity)|go:"GO:0001975"(response to amphetamine)|go:"GO:0007190"(activation of adenylate cyclase activity)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030426"(growth cone)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051412"(response to corticosterone)|go:"GO:1901841"(regulation of high voltage-gated calcium channel activity)|rcsb pdb:2N77|go:"GO:0032991"(protein-containing complex)|go:"GO:0006479"(protein methylation)|go:"GO:0014069"(postsynaptic density)|rcsb pdb:5DSU|reactome:R-HSA-8876725|rcsb pdb:4GOW|rcsb pdb:4Q57|go:"GO:0043647"(inositol phosphate metabolic process)|go:"GO:0022400"(regulation of rhodopsin mediated signaling pathway)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031432"(titin binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0031997"(N-terminal myristoylation domain binding)|go:"GO:0043274"(phospholipase binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055117"(regulation of cardiac muscle contraction)|rcsb pdb:2MG5|go:"GO:0005088"|go:"GO:0007223"(Wnt signaling pathway, calcium modulating pathway)|go:"GO:0008440"(inositol-1,4,5-trisphosphate 3-kinase activity)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0005634"(nucleus)|rcsb pdb:4JPZ|ensembl:ENST00000272298|ensembl:ENST00000291295|ensembl:ENST00000356978|ensembl:ENST00000596362|refseq:NP_001292553.1|refseq:NP_001292554.1|rcsb pdb:4BYF|reactome:R-HSA-111932|reactome:R-HSA-111933|reactome:R-HSA-111957|reactome:R-HSA-111997|reactome:R-HSA-114608|reactome:R-HSA-1445148|reactome:R-HSA-1474151|reactome:R-HSA-180024|reactome:R-HSA-1855204|reactome:R-HSA-203615|reactome:R-HSA-2514859|reactome:R-HSA-2871809|reactome:R-HSA-4086398|reactome:R-HSA-442717|reactome:R-HSA-442729|reactome:R-HSA-442745|reactome:R-HSA-442982|reactome:R-HSA-445355|reactome:R-HSA-451308|reactome:R-HSA-5218920|reactome:R-HSA-5218921|reactome:R-HSA-5607763|reactome:R-HSA-5626467|reactome:R-HSA-5627123|reactome:R-HSA-5673001|reactome:R-HSA-70221|reactome:R-HSA-983695|ensembl:ENSG00000143933|ensembl:ENSG00000160014|ensembl:ENSG00000198668|ensembl:ENSP00000272298|ensembl:ENSP00000291295|ensembl:ENSP00000349467|ensembl:ENSP00000472141|rcsb pdb:5NIN|rcsb pdb:5VMS|rcsb pdb:5WSU|rcsb pdb:5WSV|rcsb pdb:6U39|rcsb pdb:6U3A|rcsb pdb:6U3B|rcsb pdb:6U3D|rcsb pdb:2N8J|rcsb pdb:5GGM|rcsb pdb:5J8H|reactome:R-HSA-163615|reactome:R-HSA-5210891|refseq:NP_001316851.1|refseq:NP_001316852.1|refseq:NP_001316853.1|refseq:NP_001316854.1|refseq:NP_001316855.1|rcsb pdb:2N27|rcsb pdb:5DOW|rcsb pdb:5I0I|rcsb pdb:5J03|rcsb pdb:5K7L|rcsb pdb:5K8Q|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0043388"(positive regulation of DNA binding)|dip:DIP-31794N|rcsb pdb:1UP5|rcsb pdb:5JQA|rcsb pdb:5JTH|rcsb pdb:5OEO|rcsb pdb:5TP5|rcsb pdb:5TP6|rcsb pdb:5V02|rcsb pdb:5V03|rcsb pdb:5V7X|rcsb pdb:5WBX|rcsb pdb:5WC5|rcsb pdb:6B8L|rcsb pdb:6B8M|rcsb pdb:6B8N|rcsb pdb:6B8P|rcsb pdb:6B8Q|rcsb pdb:6C1D|rcsb pdb:6C1G|rcsb pdb:6C1H|rcsb pdb:6CNM|rcsb pdb:6CNN|rcsb pdb:6CNO|rcsb pdb:6FEG|rcsb pdb:6FEH|reactome:R-HSA-2025928|reactome:R-HSA-2151201|go:"GO:0034704"(calcium channel complex)|go:"GO:0010856"(adenylate cyclase activator activity)|go:"GO:0051186"(obsolete cofactor metabolic process)|go:"GO:0075206"(obsolete positive regulation by host of symbiont cAMP-mediated signal transduction)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|interpro:IPR039030|go:"GO:1902494"(catalytic complex)|go:"GO:0043234"|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0030819"(obsolete positive regulation of cAMP biosynthetic process)|rcsb pdb:6BUT|rcsb pdb:6DAD|rcsb pdb:6DAE|rcsb pdb:6DAF|rcsb pdb:6DAH|rcsb pdb:6E2F|rcsb pdb:6E2G|rcsb pdb:6EEB|rcsb pdb:6GDK|rcsb pdb:6GDL|rcsb pdb:6HCS|rcsb pdb:6JI8|rcsb pdb:6JII|rcsb pdb:6JIU|rcsb pdb:6JIY|rcsb pdb:6JRS|rcsb pdb:6JV2|rcsb pdb:6K4K|rcsb pdb:6K4L|rcsb pdb:6K4R|rcsb pdb:6MUD|rcsb pdb:6MUE|rcsb pdb:6N5W|rcsb pdb:6O5G|reactome:R-HSA-438066|reactome:R-HSA-442720|reactome:R-HSA-5673000|reactome:R-HSA-6802946|reactome:R-HSA-6802949|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9009391|reactome:R-HSA-9022535|reactome:R-HSA-9022692|reactome:R-HSA-9617324|reactome:R-HSA-9619229|reactome:R-HSA-9619483|reactome:R-HSA-9620244|go:"GO:0019722"(calcium-mediated signaling)|rcsb pdb:6PBX|rcsb pdb:6PBY|reactome:R-HSA-9649948|go:"GO:0005623"(obsolete cell)|rcsb pdb:6HR1|rcsb pdb:6OS4|rcsb pdb:6Y4P|rcsb pdb:6Y94|rcsb pdb:6Y95|reactome:R-HSA-9664323|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0016032"(viral process)|rcsb pdb:6M7H|rcsb pdb:6UZZ|rcsb pdb:6V00|rcsb pdb:6V01|rcsb pdb:6PLM|rcsb pdb:6S5T|rcsb pdb:6SZ5|rcsb pdb:6XXF|rcsb pdb:6Y4O - - - figure legend:1D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/05/03 2016/05/03 rogid:Gz4rQbzgNiEg1X01O7YWz4TmfQA9606 rogid:tTYcOd9bOh211njZVz7cYVybAMQ9606 rigid:ekoxyVMDm9vR+aM9/XU2I3BYa+U false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O43303 uniprotkb:O15078 intact:EBI-1566217|uniprotkb:O43335|uniprotkb:Q68DV9|uniprotkb:Q8NE13|uniprotkb:B7WP23|ensembl:ENSP00000370803 intact:EBI-1811944|uniprotkb:Q1PSK5|uniprotkb:Q66GS8|uniprotkb:Q9H2G6|uniprotkb:Q9H6Q7|uniprotkb:Q9H8I0|ensembl:ENSP00000448012 psi-mi:cp110_human(display_long)|uniprotkb:CP110(gene name synonym)|uniprotkb:CCP110(gene name)|psi-mi:CCP110(display_short)|uniprotkb:CEP110(gene name synonym)|uniprotkb:KIAA0419(gene name synonym)|uniprotkb:Centrosomal protein of 110 kDa(gene name synonym) psi-mi:ce290_human(display_long)|uniprotkb:CEP290(gene name)|psi-mi:CEP290(display_short)|uniprotkb:KIAA0373(gene name synonym)|uniprotkb:NPHP6(gene name synonym)|uniprotkb:Nephrocystin-6(gene name synonym)|uniprotkb:Tumor antigen se2-2(gene name synonym)|uniprotkb:Cancer/testis antigen 87(gene name synonym)|uniprotkb:BBS14(gene name synonym)|uniprotkb:Bardet-Biedl syndrome 14 protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Tsang et al. (2008) pubmed:18694559|imex:IM-25243 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-11692553|imex:IM-25243-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001310498.1|refseq:NP_001185951.2|refseq:NP_001310499.1|refseq:NP_001310500.1|refseq:NP_001310501.1|refseq:NP_055526.4|refseq:XP_011544293.1|refseq:XP_011544294.1|refseq:XP_016879397.1|dip:DIP-39892N|ensembl:ENSG00000103540(gene)|ensembl:ENST00000381396(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007099"(centriole replication)|go:"GO:0032053"(ciliary basal body organization)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0051298"(centrosome duplication)|go:"GO:1902018"(negative regulation of cilium assembly)|go:"GO:1903723"(negative regulation of centriole elongation)|interpro:IPR033207|mint:O43303|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5689880|reactome:R-HSA-8854518|reactome:R-HSA-9013424 refseq:NP_079390.3|dip:DIP-46541N|ensembl:ENSG00000198707(gene)|ensembl:ENST00000552810(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0030902"(hindbrain development)|go:"GO:0030916"(otic vesicle formation)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035580"(specific granule lumen)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048793"(pronephros development)|go:"GO:0060271"(cilium assembly)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0097711"(ciliary basal body-plasma membrane docking)|go:"GO:1905349"(ciliary transition zone assembly)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR026201|interpro:IPR032321|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-6798695|reactome:R-HSA-8854518 - - - figure legend:1D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/05/03 2016/05/03 rogid:Gvda4RoDRcY+G50iRW5T+haubps9606 rogid:89HbDVs4UVmzftFFLO/pHklTiUQ9606 rigid:vMNL2x5YtPyXhjS6zsEcFKrsf4Y false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O43303 uniprotkb:Q8IW35 intact:EBI-1566217|uniprotkb:O43335|uniprotkb:Q68DV9|uniprotkb:Q8NE13|uniprotkb:B7WP23|ensembl:ENSP00000370803 intact:EBI-1566210|uniprotkb:Q8NA71|uniprotkb:Q9H5T9|uniprotkb:B5MDY8|intact:EBI-2560935|ensembl:ENSP00000342510 psi-mi:cp110_human(display_long)|uniprotkb:CP110(gene name synonym)|uniprotkb:CCP110(gene name)|psi-mi:CCP110(display_short)|uniprotkb:CEP110(gene name synonym)|uniprotkb:KIAA0419(gene name synonym)|uniprotkb:Centrosomal protein of 110 kDa(gene name synonym) psi-mi:cep97_human(display_long)|uniprotkb:LRRIQ2(gene name synonym)|uniprotkb:Leucine-rich repeat and IQ domain-containing protein 2(gene name synonym)|uniprotkb:CEP97(gene name)|psi-mi:CEP97(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Tsang et al. (2008) pubmed:18694559|imex:IM-25243 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-11692553|imex:IM-25243-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001310498.1|refseq:NP_001185951.2|refseq:NP_001310499.1|refseq:NP_001310500.1|refseq:NP_001310501.1|refseq:NP_055526.4|refseq:XP_011544293.1|refseq:XP_011544294.1|refseq:XP_016879397.1|dip:DIP-39892N|ensembl:ENSG00000103540(gene)|ensembl:ENST00000381396(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007099"(centriole replication)|go:"GO:0032053"(ciliary basal body organization)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0051298"(centrosome duplication)|go:"GO:1902018"(negative regulation of cilium assembly)|go:"GO:1903723"(negative regulation of centriole elongation)|interpro:IPR033207|mint:O43303|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5689880|reactome:R-HSA-8854518|reactome:R-HSA-9013424 refseq:NP_078824.2|refseq:NP_001290330.1|ensembl:ENSG00000182504(gene)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0030030"(cell projection organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:1901673"(regulation of mitotic spindle assembly)|go:"GO:1902018"(negative regulation of cilium assembly)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR032675|mint:Q8IW35|reactome:R-HSA-5620912|reactome:R-HSA-9013424|ensembl:ENST00000341893(transcript) - - - figure legend:1D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/05/03 2016/05/03 rogid:Gvda4RoDRcY+G50iRW5T+haubps9606 rogid:Gz4rQbzgNiEg1X01O7YWz4TmfQA9606 rigid:vMNL2x5YtPyXhjS6zsEcFKrsf4Y false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O43303 uniprotkb:P62158 intact:EBI-1566217|uniprotkb:O43335|uniprotkb:Q68DV9|uniprotkb:Q8NE13|uniprotkb:B7WP23|ensembl:ENSP00000370803 intact:EBI-397435|uniprotkb:P02593|uniprotkb:P70667|uniprotkb:P99014|uniprotkb:Q13942|uniprotkb:Q53S29|uniprotkb:Q61379|uniprotkb:Q61380|uniprotkb:Q96HK3|uniprotkb:P0DP25|uniprotkb:P0DP24|uniprotkb:P0DP23 psi-mi:cp110_human(display_long)|uniprotkb:CP110(gene name synonym)|uniprotkb:CCP110(gene name)|psi-mi:CCP110(display_short)|uniprotkb:CEP110(gene name synonym)|uniprotkb:KIAA0419(gene name synonym)|uniprotkb:Centrosomal protein of 110 kDa(gene name synonym) psi-mi:calm_human(display_long)|uniprotkb:CALM1(gene name)|psi-mi:CALM1(display_short)|uniprotkb:CALM(gene name synonym)|uniprotkb:CAM(gene name synonym)|uniprotkb:CAM1(gene name synonym)|uniprotkb:CALM2(gene name)|psi-mi:CALM2(display_short)|uniprotkb:CAMB(gene name synonym)|uniprotkb:CALM3(gene name)|psi-mi:CALM3(display_short)|uniprotkb:CAM3(gene name synonym)|uniprotkb:CAMC(gene name synonym)|uniprotkb:CAMIII(gene name synonym)|uniprotkb:CAM2(gene name synonym)|uniprotkb:CALML2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Tsang et al. (2008) pubmed:18694559|imex:IM-25243 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-11692553|imex:IM-25243-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001310498.1|refseq:NP_001185951.2|refseq:NP_001310499.1|refseq:NP_001310500.1|refseq:NP_001310501.1|refseq:NP_055526.4|refseq:XP_011544293.1|refseq:XP_011544294.1|refseq:XP_016879397.1|dip:DIP-39892N|ensembl:ENSG00000103540(gene)|ensembl:ENST00000381396(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007099"(centriole replication)|go:"GO:0032053"(ciliary basal body organization)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0051298"(centrosome duplication)|go:"GO:1902018"(negative regulation of cilium assembly)|go:"GO:1903723"(negative regulation of centriole elongation)|interpro:IPR033207|mint:O43303|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5689880|reactome:R-HSA-8854518|reactome:R-HSA-9013424 rcsb pdb:3SUI|rcsb pdb:2LGF|rcsb pdb:2LQC|rcsb pdb:2LQP|rcsb pdb:2Y4V|rcsb pdb:4JQ0|rcsb pdb:4LZX|rcsb pdb:4M1L|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|rcsb pdb:3J41|rcsb pdb:2LL6|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0030017"(sarcomere)|go:"GO:0030801"(obsolete positive regulation of cyclic nucleotide metabolic process)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0051343"(positive regulation of cyclic-nucleotide phosphodiesterase activity)|go:"GO:0072542"(protein phosphatase activator activity)|go:"GO:1901844"(regulation of cell communication by electrical coupling involved in cardiac conduction)|rcsb pdb:2LV6|rcsb pdb:2N6A|refseq:NP_001734.1|refseq:NP_005175.2|refseq:NP_008819.1|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005876"(spindle microtubule)|go:"GO:0000922"(spindle pole)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005980"(glycogen catabolic process)|go:"GO:0006936"(muscle contraction)|go:"GO:0060315"(negative regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0002576"(platelet degranulation)|go:"GO:0060316"(positive regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0050999"(regulation of nitric-oxide synthase activity)|rcsb pdb:1AJI|rcsb pdb:1CDL|rcsb pdb:1CLL|rcsb pdb:1CTR|rcsb pdb:1IWQ|rcsb pdb:1J7O|rcsb pdb:1J7P|rcsb pdb:1K90|rcsb pdb:1K93|rcsb pdb:1L7Z|rcsb pdb:1LVC|rcsb pdb:1NKF|rcsb pdb:1PK0|rcsb pdb:1S26|rcsb pdb:1SK6|rcsb pdb:1SW8|rcsb pdb:1WRZ|rcsb pdb:1XFU|rcsb pdb:1XFV|rcsb pdb:1XFW|rcsb pdb:1XFX|rcsb pdb:1XFY|rcsb pdb:1XFZ|rcsb pdb:1Y6W|rcsb pdb:1YR5|rcsb pdb:1YRT|rcsb pdb:1YRU|rcsb pdb:1ZOT|rcsb pdb:1ZUZ|rcsb pdb:2BE6|rcsb pdb:2F3Y|rcsb pdb:2F3Z|rcsb pdb:2HF5|rcsb pdb:2I08|rcsb pdb:2JZI|rcsb pdb:2K0E|rcsb pdb:2K0F|rcsb pdb:2K0J|rcsb pdb:2K61|rcsb pdb:2KNE|rcsb pdb:2KUG|rcsb pdb:2KUH|rcsb pdb:2L53|rcsb pdb:2L7L|rcsb pdb:2R28|rcsb pdb:2V01|rcsb pdb:2V02|rcsb pdb:2VAY|rcsb pdb:2W73|rcsb pdb:2WEL|rcsb pdb:2X0G|rcsb pdb:3BYA|rcsb pdb:3DVE|rcsb pdb:3DVJ|rcsb pdb:3DVK|rcsb pdb:3DVM|rcsb pdb:3EWT|rcsb pdb:3EWV|rcsb pdb:3G43|rcsb pdb:3HR4|rcsb pdb:3O77|rcsb pdb:3O78|rcsb pdb:3OXQ|rcsb pdb:3UCT|rcsb pdb:3UCW|rcsb pdb:3UCY|rcsb pdb:4DCK|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0000165"(MAPK cascade)|rcsb pdb:2M0J|rcsb pdb:2M0K|rcsb pdb:4UMO|rcsb pdb:4V0C|go:"GO:0031982"(vesicle)|rcsb pdb:4Q5U|rcsb pdb:4UPU|reactome:R-HSA-2672351|reactome:R-HSA-418359|reactome:R-HSA-425561|reactome:R-HSA-5576892|reactome:R-HSA-5578775|reactome:R-HSA-936837|refseq:NP_001292555.1|rcsb pdb:4OVN|rcsb pdb:5COC|go:"GO:0021762"(substantia nigra development)|go:"GO:0070062"(extracellular exosome)|rcsb pdb:4BW7|rcsb pdb:4BW8|rcsb pdb:4L79|rcsb pdb:5DBR|rcsb pdb:4DJC|rcsb pdb:2M55|rcsb pdb:2LL7|go:"GO:0019855"(calcium channel inhibitor activity)|go:"GO:0001975"(response to amphetamine)|go:"GO:0007190"(activation of adenylate cyclase activity)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030426"(growth cone)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051412"(response to corticosterone)|go:"GO:1901841"(regulation of high voltage-gated calcium channel activity)|rcsb pdb:2N77|go:"GO:0032991"(protein-containing complex)|go:"GO:0006479"(protein methylation)|go:"GO:0014069"(postsynaptic density)|rcsb pdb:5DSU|reactome:R-HSA-8876725|rcsb pdb:4GOW|rcsb pdb:4Q57|go:"GO:0043647"(inositol phosphate metabolic process)|go:"GO:0022400"(regulation of rhodopsin mediated signaling pathway)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031432"(titin binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0031997"(N-terminal myristoylation domain binding)|go:"GO:0043274"(phospholipase binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055117"(regulation of cardiac muscle contraction)|rcsb pdb:2MG5|go:"GO:0005088"|go:"GO:0007223"(Wnt signaling pathway, calcium modulating pathway)|go:"GO:0008440"(inositol-1,4,5-trisphosphate 3-kinase activity)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0005634"(nucleus)|rcsb pdb:4JPZ|ensembl:ENST00000272298|ensembl:ENST00000291295|ensembl:ENST00000356978|ensembl:ENST00000596362|refseq:NP_001292553.1|refseq:NP_001292554.1|rcsb pdb:4BYF|reactome:R-HSA-111932|reactome:R-HSA-111933|reactome:R-HSA-111957|reactome:R-HSA-111997|reactome:R-HSA-114608|reactome:R-HSA-1445148|reactome:R-HSA-1474151|reactome:R-HSA-180024|reactome:R-HSA-1855204|reactome:R-HSA-203615|reactome:R-HSA-2514859|reactome:R-HSA-2871809|reactome:R-HSA-4086398|reactome:R-HSA-442717|reactome:R-HSA-442729|reactome:R-HSA-442745|reactome:R-HSA-442982|reactome:R-HSA-445355|reactome:R-HSA-451308|reactome:R-HSA-5218920|reactome:R-HSA-5218921|reactome:R-HSA-5607763|reactome:R-HSA-5626467|reactome:R-HSA-5627123|reactome:R-HSA-5673001|reactome:R-HSA-70221|reactome:R-HSA-983695|ensembl:ENSG00000143933|ensembl:ENSG00000160014|ensembl:ENSG00000198668|ensembl:ENSP00000272298|ensembl:ENSP00000291295|ensembl:ENSP00000349467|ensembl:ENSP00000472141|rcsb pdb:5NIN|rcsb pdb:5VMS|rcsb pdb:5WSU|rcsb pdb:5WSV|rcsb pdb:6U39|rcsb pdb:6U3A|rcsb pdb:6U3B|rcsb pdb:6U3D|rcsb pdb:2N8J|rcsb pdb:5GGM|rcsb pdb:5J8H|reactome:R-HSA-163615|reactome:R-HSA-5210891|refseq:NP_001316851.1|refseq:NP_001316852.1|refseq:NP_001316853.1|refseq:NP_001316854.1|refseq:NP_001316855.1|rcsb pdb:2N27|rcsb pdb:5DOW|rcsb pdb:5I0I|rcsb pdb:5J03|rcsb pdb:5K7L|rcsb pdb:5K8Q|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0043388"(positive regulation of DNA binding)|dip:DIP-31794N|rcsb pdb:1UP5|rcsb pdb:5JQA|rcsb pdb:5JTH|rcsb pdb:5OEO|rcsb pdb:5TP5|rcsb pdb:5TP6|rcsb pdb:5V02|rcsb pdb:5V03|rcsb pdb:5V7X|rcsb pdb:5WBX|rcsb pdb:5WC5|rcsb pdb:6B8L|rcsb pdb:6B8M|rcsb pdb:6B8N|rcsb pdb:6B8P|rcsb pdb:6B8Q|rcsb pdb:6C1D|rcsb pdb:6C1G|rcsb pdb:6C1H|rcsb pdb:6CNM|rcsb pdb:6CNN|rcsb pdb:6CNO|rcsb pdb:6FEG|rcsb pdb:6FEH|reactome:R-HSA-2025928|reactome:R-HSA-2151201|go:"GO:0034704"(calcium channel complex)|go:"GO:0010856"(adenylate cyclase activator activity)|go:"GO:0051186"(obsolete cofactor metabolic process)|go:"GO:0075206"(obsolete positive regulation by host of symbiont cAMP-mediated signal transduction)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|interpro:IPR039030|go:"GO:1902494"(catalytic complex)|go:"GO:0043234"|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0030819"(obsolete positive regulation of cAMP biosynthetic process)|rcsb pdb:6BUT|rcsb pdb:6DAD|rcsb pdb:6DAE|rcsb pdb:6DAF|rcsb pdb:6DAH|rcsb pdb:6E2F|rcsb pdb:6E2G|rcsb pdb:6EEB|rcsb pdb:6GDK|rcsb pdb:6GDL|rcsb pdb:6HCS|rcsb pdb:6JI8|rcsb pdb:6JII|rcsb pdb:6JIU|rcsb pdb:6JIY|rcsb pdb:6JRS|rcsb pdb:6JV2|rcsb pdb:6K4K|rcsb pdb:6K4L|rcsb pdb:6K4R|rcsb pdb:6MUD|rcsb pdb:6MUE|rcsb pdb:6N5W|rcsb pdb:6O5G|reactome:R-HSA-438066|reactome:R-HSA-442720|reactome:R-HSA-5673000|reactome:R-HSA-6802946|reactome:R-HSA-6802949|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9009391|reactome:R-HSA-9022535|reactome:R-HSA-9022692|reactome:R-HSA-9617324|reactome:R-HSA-9619229|reactome:R-HSA-9619483|reactome:R-HSA-9620244|go:"GO:0019722"(calcium-mediated signaling)|rcsb pdb:6PBX|rcsb pdb:6PBY|reactome:R-HSA-9649948|go:"GO:0005623"(obsolete cell)|rcsb pdb:6HR1|rcsb pdb:6OS4|rcsb pdb:6Y4P|rcsb pdb:6Y94|rcsb pdb:6Y95|reactome:R-HSA-9664323|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0016032"(viral process)|rcsb pdb:6M7H|rcsb pdb:6UZZ|rcsb pdb:6V00|rcsb pdb:6V01|rcsb pdb:6PLM|rcsb pdb:6S5T|rcsb pdb:6SZ5|rcsb pdb:6XXF|rcsb pdb:6Y4O - - - figure legend:1D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/05/03 2016/05/03 rogid:Gvda4RoDRcY+G50iRW5T+haubps9606 rogid:tTYcOd9bOh211njZVz7cYVybAMQ9606 rigid:vMNL2x5YtPyXhjS6zsEcFKrsf4Y false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O15078 uniprotkb:O43303 intact:EBI-1811944|uniprotkb:Q1PSK5|uniprotkb:Q66GS8|uniprotkb:Q9H2G6|uniprotkb:Q9H6Q7|uniprotkb:Q9H8I0|ensembl:ENSP00000448012 intact:EBI-1566217|uniprotkb:O43335|uniprotkb:Q68DV9|uniprotkb:Q8NE13|uniprotkb:B7WP23|ensembl:ENSP00000370803 psi-mi:ce290_human(display_long)|uniprotkb:CEP290(gene name)|psi-mi:CEP290(display_short)|uniprotkb:KIAA0373(gene name synonym)|uniprotkb:NPHP6(gene name synonym)|uniprotkb:Nephrocystin-6(gene name synonym)|uniprotkb:Tumor antigen se2-2(gene name synonym)|uniprotkb:Cancer/testis antigen 87(gene name synonym)|uniprotkb:BBS14(gene name synonym)|uniprotkb:Bardet-Biedl syndrome 14 protein(gene name synonym) psi-mi:cp110_human(display_long)|uniprotkb:CP110(gene name synonym)|uniprotkb:CCP110(gene name)|psi-mi:CCP110(display_short)|uniprotkb:CEP110(gene name synonym)|uniprotkb:KIAA0419(gene name synonym)|uniprotkb:Centrosomal protein of 110 kDa(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Tsang et al. (2008) pubmed:18694559|imex:IM-25243 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-11692567|imex:IM-25243-12 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079390.3|dip:DIP-46541N|ensembl:ENSG00000198707(gene)|ensembl:ENST00000552810(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0030902"(hindbrain development)|go:"GO:0030916"(otic vesicle formation)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035580"(specific granule lumen)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048793"(pronephros development)|go:"GO:0060271"(cilium assembly)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0097711"(ciliary basal body-plasma membrane docking)|go:"GO:1905349"(ciliary transition zone assembly)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR026201|interpro:IPR032321|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-6798695|reactome:R-HSA-8854518 refseq:NP_001310498.1|refseq:NP_001185951.2|refseq:NP_001310499.1|refseq:NP_001310500.1|refseq:NP_001310501.1|refseq:NP_055526.4|refseq:XP_011544293.1|refseq:XP_011544294.1|refseq:XP_016879397.1|dip:DIP-39892N|ensembl:ENSG00000103540(gene)|ensembl:ENST00000381396(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007099"(centriole replication)|go:"GO:0032053"(ciliary basal body organization)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0051298"(centrosome duplication)|go:"GO:1902018"(negative regulation of cilium assembly)|go:"GO:1903723"(negative regulation of centriole elongation)|interpro:IPR033207|mint:O43303|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5689880|reactome:R-HSA-8854518|reactome:R-HSA-9013424 - - - figure legend:1D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/05/03 2016/05/03 rogid:89HbDVs4UVmzftFFLO/pHklTiUQ9606 rogid:Gvda4RoDRcY+G50iRW5T+haubps9606 rigid:Mt5EJbMSbMebEHqzvQUMv9X5pjc false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O15078 uniprotkb:O43303 intact:EBI-1811944|uniprotkb:Q1PSK5|uniprotkb:Q66GS8|uniprotkb:Q9H2G6|uniprotkb:Q9H6Q7|uniprotkb:Q9H8I0|ensembl:ENSP00000448012 intact:EBI-1566217|uniprotkb:O43335|uniprotkb:Q68DV9|uniprotkb:Q8NE13|uniprotkb:B7WP23|ensembl:ENSP00000370803 psi-mi:ce290_human(display_long)|uniprotkb:CEP290(gene name)|psi-mi:CEP290(display_short)|uniprotkb:KIAA0373(gene name synonym)|uniprotkb:NPHP6(gene name synonym)|uniprotkb:Nephrocystin-6(gene name synonym)|uniprotkb:Tumor antigen se2-2(gene name synonym)|uniprotkb:Cancer/testis antigen 87(gene name synonym)|uniprotkb:BBS14(gene name synonym)|uniprotkb:Bardet-Biedl syndrome 14 protein(gene name synonym) psi-mi:cp110_human(display_long)|uniprotkb:CP110(gene name synonym)|uniprotkb:CCP110(gene name)|psi-mi:CCP110(display_short)|uniprotkb:CEP110(gene name synonym)|uniprotkb:KIAA0419(gene name synonym)|uniprotkb:Centrosomal protein of 110 kDa(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Tsang et al. (2008) pubmed:18694559|imex:IM-25243 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-11692580|imex:IM-25243-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079390.3|dip:DIP-46541N|ensembl:ENSG00000198707(gene)|ensembl:ENST00000552810(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0030902"(hindbrain development)|go:"GO:0030916"(otic vesicle formation)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035580"(specific granule lumen)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048793"(pronephros development)|go:"GO:0060271"(cilium assembly)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0097711"(ciliary basal body-plasma membrane docking)|go:"GO:1905349"(ciliary transition zone assembly)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR026201|interpro:IPR032321|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-6798695|reactome:R-HSA-8854518 refseq:NP_001310498.1|refseq:NP_001185951.2|refseq:NP_001310499.1|refseq:NP_001310500.1|refseq:NP_001310501.1|refseq:NP_055526.4|refseq:XP_011544293.1|refseq:XP_011544294.1|refseq:XP_016879397.1|dip:DIP-39892N|ensembl:ENSG00000103540(gene)|ensembl:ENST00000381396(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007099"(centriole replication)|go:"GO:0032053"(ciliary basal body organization)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0051298"(centrosome duplication)|go:"GO:1902018"(negative regulation of cilium assembly)|go:"GO:1903723"(negative regulation of centriole elongation)|interpro:IPR033207|mint:O43303|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5689880|reactome:R-HSA-8854518|reactome:R-HSA-9013424 - - - figure legend:1E|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/05/03 2016/05/03 rogid:89HbDVs4UVmzftFFLO/pHklTiUQ9606 rogid:Gvda4RoDRcY+G50iRW5T+haubps9606 rigid:Mt5EJbMSbMebEHqzvQUMv9X5pjc false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O15078 uniprotkb:O43303 intact:EBI-1811944|uniprotkb:Q1PSK5|uniprotkb:Q66GS8|uniprotkb:Q9H2G6|uniprotkb:Q9H6Q7|uniprotkb:Q9H8I0|ensembl:ENSP00000448012 intact:EBI-1566217|uniprotkb:O43335|uniprotkb:Q68DV9|uniprotkb:Q8NE13|uniprotkb:B7WP23|ensembl:ENSP00000370803 psi-mi:ce290_human(display_long)|uniprotkb:CEP290(gene name)|psi-mi:CEP290(display_short)|uniprotkb:KIAA0373(gene name synonym)|uniprotkb:NPHP6(gene name synonym)|uniprotkb:Nephrocystin-6(gene name synonym)|uniprotkb:Tumor antigen se2-2(gene name synonym)|uniprotkb:Cancer/testis antigen 87(gene name synonym)|uniprotkb:BBS14(gene name synonym)|uniprotkb:Bardet-Biedl syndrome 14 protein(gene name synonym) psi-mi:cp110_human(display_long)|uniprotkb:CP110(gene name synonym)|uniprotkb:CCP110(gene name)|psi-mi:CCP110(display_short)|uniprotkb:CEP110(gene name synonym)|uniprotkb:KIAA0419(gene name synonym)|uniprotkb:Centrosomal protein of 110 kDa(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Tsang et al. (2008) pubmed:18694559|imex:IM-25243 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-11692584|imex:IM-25243-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079390.3|dip:DIP-46541N|ensembl:ENSG00000198707(gene)|ensembl:ENST00000552810(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0030902"(hindbrain development)|go:"GO:0030916"(otic vesicle formation)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035580"(specific granule lumen)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048793"(pronephros development)|go:"GO:0060271"(cilium assembly)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0097711"(ciliary basal body-plasma membrane docking)|go:"GO:1905349"(ciliary transition zone assembly)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR026201|interpro:IPR032321|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-6798695|reactome:R-HSA-8854518 refseq:NP_001310498.1|refseq:NP_001185951.2|refseq:NP_001310499.1|refseq:NP_001310500.1|refseq:NP_001310501.1|refseq:NP_055526.4|refseq:XP_011544293.1|refseq:XP_011544294.1|refseq:XP_016879397.1|dip:DIP-39892N|ensembl:ENSG00000103540(gene)|ensembl:ENST00000381396(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007099"(centriole replication)|go:"GO:0032053"(ciliary basal body organization)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0051298"(centrosome duplication)|go:"GO:1902018"(negative regulation of cilium assembly)|go:"GO:1903723"(negative regulation of centriole elongation)|interpro:IPR033207|mint:O43303|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5689880|reactome:R-HSA-8854518|reactome:R-HSA-9013424 - - - figure legend:1E|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/05/03 2016/05/03 rogid:89HbDVs4UVmzftFFLO/pHklTiUQ9606 rogid:Gvda4RoDRcY+G50iRW5T+haubps9606 rigid:Oif/zf5ls3FP6O7pQ8Raq3C+Cw0 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O15078 uniprotkb:O95613 intact:EBI-1811944|uniprotkb:Q1PSK5|uniprotkb:Q66GS8|uniprotkb:Q9H2G6|uniprotkb:Q9H6Q7|uniprotkb:Q9H8I0|ensembl:ENSP00000448012 intact:EBI-530012|uniprotkb:O43152|uniprotkb:Q7Z7C9|intact:EBI-28971202|ensembl:ENSP00000352572 psi-mi:ce290_human(display_long)|uniprotkb:CEP290(gene name)|psi-mi:CEP290(display_short)|uniprotkb:KIAA0373(gene name synonym)|uniprotkb:NPHP6(gene name synonym)|uniprotkb:Nephrocystin-6(gene name synonym)|uniprotkb:Tumor antigen se2-2(gene name synonym)|uniprotkb:Cancer/testis antigen 87(gene name synonym)|uniprotkb:BBS14(gene name synonym)|uniprotkb:Bardet-Biedl syndrome 14 protein(gene name synonym) psi-mi:pcnt_human(display_long)|uniprotkb:Pericentrin-B(gene name synonym)|uniprotkb:Kendrin(gene name synonym)|uniprotkb:PCNT(gene name)|psi-mi:PCNT(display_short)|uniprotkb:KIAA0402(gene name synonym)|uniprotkb:PCNT2(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Tsang et al. (2008) pubmed:18694559|imex:IM-25243 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-11692584|imex:IM-25243-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079390.3|dip:DIP-46541N|ensembl:ENSG00000198707(gene)|ensembl:ENST00000552810(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0030902"(hindbrain development)|go:"GO:0030916"(otic vesicle formation)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035580"(specific granule lumen)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048793"(pronephros development)|go:"GO:0060271"(cilium assembly)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0097711"(ciliary basal body-plasma membrane docking)|go:"GO:1905349"(ciliary transition zone assembly)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR026201|interpro:IPR032321|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-6798695|reactome:R-HSA-8854518 ensembl:ENSP00000352572|refseq:NP_006022.3|refseq:NP_001302458.1|ensembl:ENSG00000160299(gene)|ensembl:ENST00000359568(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0034451"(centriolar satellite)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0090316"(positive regulation of intracellular protein transport)|interpro:IPR019528|interpro:IPR028745|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|reactome:R-HSA-9613829|reactome:R-HSA-9615710|reactome:R-HSA-9646399|dip:DIP-33829N - - - figure legend:1E|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/05/03 2016/05/03 rogid:89HbDVs4UVmzftFFLO/pHklTiUQ9606 rogid:8YHnOQE3b77ocsel2oAdsqvE+js9606 rigid:Oif/zf5ls3FP6O7pQ8Raq3C+Cw0 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P62158 uniprotkb:O15078 intact:EBI-397435|uniprotkb:P02593|uniprotkb:P70667|uniprotkb:P99014|uniprotkb:Q13942|uniprotkb:Q53S29|uniprotkb:Q61379|uniprotkb:Q61380|uniprotkb:Q96HK3|uniprotkb:P0DP25|uniprotkb:P0DP24|uniprotkb:P0DP23 intact:EBI-1811944|uniprotkb:Q1PSK5|uniprotkb:Q66GS8|uniprotkb:Q9H2G6|uniprotkb:Q9H6Q7|uniprotkb:Q9H8I0|ensembl:ENSP00000448012 psi-mi:calm_human(display_long)|uniprotkb:CALM1(gene name)|psi-mi:CALM1(display_short)|uniprotkb:CALM(gene name synonym)|uniprotkb:CAM(gene name synonym)|uniprotkb:CAM1(gene name synonym)|uniprotkb:CALM2(gene name)|psi-mi:CALM2(display_short)|uniprotkb:CAMB(gene name synonym)|uniprotkb:CALM3(gene name)|psi-mi:CALM3(display_short)|uniprotkb:CAM3(gene name synonym)|uniprotkb:CAMC(gene name synonym)|uniprotkb:CAMIII(gene name synonym)|uniprotkb:CAM2(gene name synonym)|uniprotkb:CALML2(gene name synonym) psi-mi:ce290_human(display_long)|uniprotkb:CEP290(gene name)|psi-mi:CEP290(display_short)|uniprotkb:KIAA0373(gene name synonym)|uniprotkb:NPHP6(gene name synonym)|uniprotkb:Nephrocystin-6(gene name synonym)|uniprotkb:Tumor antigen se2-2(gene name synonym)|uniprotkb:Cancer/testis antigen 87(gene name synonym)|uniprotkb:BBS14(gene name synonym)|uniprotkb:Bardet-Biedl syndrome 14 protein(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Tsang et al. (2008) pubmed:18694559|imex:IM-25243 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-11692589|imex:IM-25243-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:3SUI|rcsb pdb:2LGF|rcsb pdb:2LQC|rcsb pdb:2LQP|rcsb pdb:2Y4V|rcsb pdb:4JQ0|rcsb pdb:4LZX|rcsb pdb:4M1L|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|rcsb pdb:3J41|rcsb pdb:2LL6|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0030017"(sarcomere)|go:"GO:0030801"(obsolete positive regulation of cyclic nucleotide metabolic process)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0051343"(positive regulation of cyclic-nucleotide phosphodiesterase activity)|go:"GO:0072542"(protein phosphatase activator activity)|go:"GO:1901844"(regulation of cell communication by electrical coupling involved in cardiac conduction)|rcsb pdb:2LV6|rcsb pdb:2N6A|refseq:NP_001734.1|refseq:NP_005175.2|refseq:NP_008819.1|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005876"(spindle microtubule)|go:"GO:0000922"(spindle pole)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005980"(glycogen catabolic process)|go:"GO:0006936"(muscle contraction)|go:"GO:0060315"(negative regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0002576"(platelet degranulation)|go:"GO:0060316"(positive regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0050999"(regulation of nitric-oxide synthase activity)|rcsb pdb:1AJI|rcsb pdb:1CDL|rcsb pdb:1CLL|rcsb pdb:1CTR|rcsb pdb:1IWQ|rcsb pdb:1J7O|rcsb pdb:1J7P|rcsb pdb:1K90|rcsb pdb:1K93|rcsb pdb:1L7Z|rcsb pdb:1LVC|rcsb pdb:1NKF|rcsb pdb:1PK0|rcsb pdb:1S26|rcsb pdb:1SK6|rcsb pdb:1SW8|rcsb pdb:1WRZ|rcsb pdb:1XFU|rcsb pdb:1XFV|rcsb pdb:1XFW|rcsb pdb:1XFX|rcsb pdb:1XFY|rcsb pdb:1XFZ|rcsb pdb:1Y6W|rcsb pdb:1YR5|rcsb pdb:1YRT|rcsb pdb:1YRU|rcsb pdb:1ZOT|rcsb pdb:1ZUZ|rcsb pdb:2BE6|rcsb pdb:2F3Y|rcsb pdb:2F3Z|rcsb pdb:2HF5|rcsb pdb:2I08|rcsb pdb:2JZI|rcsb pdb:2K0E|rcsb pdb:2K0F|rcsb pdb:2K0J|rcsb pdb:2K61|rcsb pdb:2KNE|rcsb pdb:2KUG|rcsb pdb:2KUH|rcsb pdb:2L53|rcsb pdb:2L7L|rcsb pdb:2R28|rcsb pdb:2V01|rcsb pdb:2V02|rcsb pdb:2VAY|rcsb pdb:2W73|rcsb pdb:2WEL|rcsb pdb:2X0G|rcsb pdb:3BYA|rcsb pdb:3DVE|rcsb pdb:3DVJ|rcsb pdb:3DVK|rcsb pdb:3DVM|rcsb pdb:3EWT|rcsb pdb:3EWV|rcsb pdb:3G43|rcsb pdb:3HR4|rcsb pdb:3O77|rcsb pdb:3O78|rcsb pdb:3OXQ|rcsb pdb:3UCT|rcsb pdb:3UCW|rcsb pdb:3UCY|rcsb pdb:4DCK|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0000165"(MAPK cascade)|rcsb pdb:2M0J|rcsb pdb:2M0K|rcsb pdb:4UMO|rcsb pdb:4V0C|go:"GO:0031982"(vesicle)|rcsb pdb:4Q5U|rcsb pdb:4UPU|reactome:R-HSA-2672351|reactome:R-HSA-418359|reactome:R-HSA-425561|reactome:R-HSA-5576892|reactome:R-HSA-5578775|reactome:R-HSA-936837|refseq:NP_001292555.1|rcsb pdb:4OVN|rcsb pdb:5COC|go:"GO:0021762"(substantia nigra development)|go:"GO:0070062"(extracellular exosome)|rcsb pdb:4BW7|rcsb pdb:4BW8|rcsb pdb:4L79|rcsb pdb:5DBR|rcsb pdb:4DJC|rcsb pdb:2M55|rcsb pdb:2LL7|go:"GO:0019855"(calcium channel inhibitor activity)|go:"GO:0001975"(response to amphetamine)|go:"GO:0007190"(activation of adenylate cyclase activity)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030426"(growth cone)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051412"(response to corticosterone)|go:"GO:1901841"(regulation of high voltage-gated calcium channel activity)|rcsb pdb:2N77|go:"GO:0032991"(protein-containing complex)|go:"GO:0006479"(protein methylation)|go:"GO:0014069"(postsynaptic density)|rcsb pdb:5DSU|reactome:R-HSA-8876725|rcsb pdb:4GOW|rcsb pdb:4Q57|go:"GO:0043647"(inositol phosphate metabolic process)|go:"GO:0022400"(regulation of rhodopsin mediated signaling pathway)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031432"(titin binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0031997"(N-terminal myristoylation domain binding)|go:"GO:0043274"(phospholipase binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055117"(regulation of cardiac muscle contraction)|rcsb pdb:2MG5|go:"GO:0005088"|go:"GO:0007223"(Wnt signaling pathway, calcium modulating pathway)|go:"GO:0008440"(inositol-1,4,5-trisphosphate 3-kinase activity)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0005634"(nucleus)|rcsb pdb:4JPZ|ensembl:ENST00000272298|ensembl:ENST00000291295|ensembl:ENST00000356978|ensembl:ENST00000596362|refseq:NP_001292553.1|refseq:NP_001292554.1|rcsb pdb:4BYF|reactome:R-HSA-111932|reactome:R-HSA-111933|reactome:R-HSA-111957|reactome:R-HSA-111997|reactome:R-HSA-114608|reactome:R-HSA-1445148|reactome:R-HSA-1474151|reactome:R-HSA-180024|reactome:R-HSA-1855204|reactome:R-HSA-203615|reactome:R-HSA-2514859|reactome:R-HSA-2871809|reactome:R-HSA-4086398|reactome:R-HSA-442717|reactome:R-HSA-442729|reactome:R-HSA-442745|reactome:R-HSA-442982|reactome:R-HSA-445355|reactome:R-HSA-451308|reactome:R-HSA-5218920|reactome:R-HSA-5218921|reactome:R-HSA-5607763|reactome:R-HSA-5626467|reactome:R-HSA-5627123|reactome:R-HSA-5673001|reactome:R-HSA-70221|reactome:R-HSA-983695|ensembl:ENSG00000143933|ensembl:ENSG00000160014|ensembl:ENSG00000198668|ensembl:ENSP00000272298|ensembl:ENSP00000291295|ensembl:ENSP00000349467|ensembl:ENSP00000472141|rcsb pdb:5NIN|rcsb pdb:5VMS|rcsb pdb:5WSU|rcsb pdb:5WSV|rcsb pdb:6U39|rcsb pdb:6U3A|rcsb pdb:6U3B|rcsb pdb:6U3D|rcsb pdb:2N8J|rcsb pdb:5GGM|rcsb pdb:5J8H|reactome:R-HSA-163615|reactome:R-HSA-5210891|refseq:NP_001316851.1|refseq:NP_001316852.1|refseq:NP_001316853.1|refseq:NP_001316854.1|refseq:NP_001316855.1|rcsb pdb:2N27|rcsb pdb:5DOW|rcsb pdb:5I0I|rcsb pdb:5J03|rcsb pdb:5K7L|rcsb pdb:5K8Q|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0043388"(positive regulation of DNA binding)|dip:DIP-31794N|rcsb pdb:1UP5|rcsb pdb:5JQA|rcsb pdb:5JTH|rcsb pdb:5OEO|rcsb pdb:5TP5|rcsb pdb:5TP6|rcsb pdb:5V02|rcsb pdb:5V03|rcsb pdb:5V7X|rcsb pdb:5WBX|rcsb pdb:5WC5|rcsb pdb:6B8L|rcsb pdb:6B8M|rcsb pdb:6B8N|rcsb pdb:6B8P|rcsb pdb:6B8Q|rcsb pdb:6C1D|rcsb pdb:6C1G|rcsb pdb:6C1H|rcsb pdb:6CNM|rcsb pdb:6CNN|rcsb pdb:6CNO|rcsb pdb:6FEG|rcsb pdb:6FEH|reactome:R-HSA-2025928|reactome:R-HSA-2151201|go:"GO:0034704"(calcium channel complex)|go:"GO:0010856"(adenylate cyclase activator activity)|go:"GO:0051186"(obsolete cofactor metabolic process)|go:"GO:0075206"(obsolete positive regulation by host of symbiont cAMP-mediated signal transduction)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|interpro:IPR039030|go:"GO:1902494"(catalytic complex)|go:"GO:0043234"|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0030819"(obsolete positive regulation of cAMP biosynthetic process)|rcsb pdb:6BUT|rcsb pdb:6DAD|rcsb pdb:6DAE|rcsb pdb:6DAF|rcsb pdb:6DAH|rcsb pdb:6E2F|rcsb pdb:6E2G|rcsb pdb:6EEB|rcsb pdb:6GDK|rcsb pdb:6GDL|rcsb pdb:6HCS|rcsb pdb:6JI8|rcsb pdb:6JII|rcsb pdb:6JIU|rcsb pdb:6JIY|rcsb pdb:6JRS|rcsb pdb:6JV2|rcsb pdb:6K4K|rcsb pdb:6K4L|rcsb pdb:6K4R|rcsb pdb:6MUD|rcsb pdb:6MUE|rcsb pdb:6N5W|rcsb pdb:6O5G|reactome:R-HSA-438066|reactome:R-HSA-442720|reactome:R-HSA-5673000|reactome:R-HSA-6802946|reactome:R-HSA-6802949|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9009391|reactome:R-HSA-9022535|reactome:R-HSA-9022692|reactome:R-HSA-9617324|reactome:R-HSA-9619229|reactome:R-HSA-9619483|reactome:R-HSA-9620244|go:"GO:0019722"(calcium-mediated signaling)|rcsb pdb:6PBX|rcsb pdb:6PBY|reactome:R-HSA-9649948|go:"GO:0005623"(obsolete cell)|rcsb pdb:6HR1|rcsb pdb:6OS4|rcsb pdb:6Y4P|rcsb pdb:6Y94|rcsb pdb:6Y95|reactome:R-HSA-9664323|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0016032"(viral process)|rcsb pdb:6M7H|rcsb pdb:6UZZ|rcsb pdb:6V00|rcsb pdb:6V01|rcsb pdb:6PLM|rcsb pdb:6S5T|rcsb pdb:6SZ5|rcsb pdb:6XXF|rcsb pdb:6Y4O refseq:NP_079390.3|dip:DIP-46541N|ensembl:ENSG00000198707(gene)|ensembl:ENST00000552810(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0030902"(hindbrain development)|go:"GO:0030916"(otic vesicle formation)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035580"(specific granule lumen)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048793"(pronephros development)|go:"GO:0060271"(cilium assembly)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0097711"(ciliary basal body-plasma membrane docking)|go:"GO:1905349"(ciliary transition zone assembly)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR026201|interpro:IPR032321|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-6798695|reactome:R-HSA-8854518 - - - figure legend:1E|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/05/03 2016/05/03 rogid:tTYcOd9bOh211njZVz7cYVybAMQ9606 rogid:89HbDVs4UVmzftFFLO/pHklTiUQ9606 rigid:DHoJY9Z7HUKDG6HeuAMOYLkKooU false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P62158 uniprotkb:O43303 intact:EBI-397435|uniprotkb:P02593|uniprotkb:P70667|uniprotkb:P99014|uniprotkb:Q13942|uniprotkb:Q53S29|uniprotkb:Q61379|uniprotkb:Q61380|uniprotkb:Q96HK3|uniprotkb:P0DP25|uniprotkb:P0DP24|uniprotkb:P0DP23 intact:EBI-1566217|uniprotkb:O43335|uniprotkb:Q68DV9|uniprotkb:Q8NE13|uniprotkb:B7WP23|ensembl:ENSP00000370803 psi-mi:calm_human(display_long)|uniprotkb:CALM1(gene name)|psi-mi:CALM1(display_short)|uniprotkb:CALM(gene name synonym)|uniprotkb:CAM(gene name synonym)|uniprotkb:CAM1(gene name synonym)|uniprotkb:CALM2(gene name)|psi-mi:CALM2(display_short)|uniprotkb:CAMB(gene name synonym)|uniprotkb:CALM3(gene name)|psi-mi:CALM3(display_short)|uniprotkb:CAM3(gene name synonym)|uniprotkb:CAMC(gene name synonym)|uniprotkb:CAMIII(gene name synonym)|uniprotkb:CAM2(gene name synonym)|uniprotkb:CALML2(gene name synonym) psi-mi:cp110_human(display_long)|uniprotkb:CP110(gene name synonym)|uniprotkb:CCP110(gene name)|psi-mi:CCP110(display_short)|uniprotkb:CEP110(gene name synonym)|uniprotkb:KIAA0419(gene name synonym)|uniprotkb:Centrosomal protein of 110 kDa(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Tsang et al. (2008) pubmed:18694559|imex:IM-25243 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-11692589|imex:IM-25243-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:3SUI|rcsb pdb:2LGF|rcsb pdb:2LQC|rcsb pdb:2LQP|rcsb pdb:2Y4V|rcsb pdb:4JQ0|rcsb pdb:4LZX|rcsb pdb:4M1L|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|rcsb pdb:3J41|rcsb pdb:2LL6|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0030017"(sarcomere)|go:"GO:0030801"(obsolete positive regulation of cyclic nucleotide metabolic process)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0051343"(positive regulation of cyclic-nucleotide phosphodiesterase activity)|go:"GO:0072542"(protein phosphatase activator activity)|go:"GO:1901844"(regulation of cell communication by electrical coupling involved in cardiac conduction)|rcsb pdb:2LV6|rcsb pdb:2N6A|refseq:NP_001734.1|refseq:NP_005175.2|refseq:NP_008819.1|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005876"(spindle microtubule)|go:"GO:0000922"(spindle pole)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005980"(glycogen catabolic process)|go:"GO:0006936"(muscle contraction)|go:"GO:0060315"(negative regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0002576"(platelet degranulation)|go:"GO:0060316"(positive regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0050999"(regulation of nitric-oxide synthase activity)|rcsb pdb:1AJI|rcsb pdb:1CDL|rcsb pdb:1CLL|rcsb pdb:1CTR|rcsb pdb:1IWQ|rcsb pdb:1J7O|rcsb pdb:1J7P|rcsb pdb:1K90|rcsb pdb:1K93|rcsb pdb:1L7Z|rcsb pdb:1LVC|rcsb pdb:1NKF|rcsb pdb:1PK0|rcsb pdb:1S26|rcsb pdb:1SK6|rcsb pdb:1SW8|rcsb pdb:1WRZ|rcsb pdb:1XFU|rcsb pdb:1XFV|rcsb pdb:1XFW|rcsb pdb:1XFX|rcsb pdb:1XFY|rcsb pdb:1XFZ|rcsb pdb:1Y6W|rcsb pdb:1YR5|rcsb pdb:1YRT|rcsb pdb:1YRU|rcsb pdb:1ZOT|rcsb pdb:1ZUZ|rcsb pdb:2BE6|rcsb pdb:2F3Y|rcsb pdb:2F3Z|rcsb pdb:2HF5|rcsb pdb:2I08|rcsb pdb:2JZI|rcsb pdb:2K0E|rcsb pdb:2K0F|rcsb pdb:2K0J|rcsb pdb:2K61|rcsb pdb:2KNE|rcsb pdb:2KUG|rcsb pdb:2KUH|rcsb pdb:2L53|rcsb pdb:2L7L|rcsb pdb:2R28|rcsb pdb:2V01|rcsb pdb:2V02|rcsb pdb:2VAY|rcsb pdb:2W73|rcsb pdb:2WEL|rcsb pdb:2X0G|rcsb pdb:3BYA|rcsb pdb:3DVE|rcsb pdb:3DVJ|rcsb pdb:3DVK|rcsb pdb:3DVM|rcsb pdb:3EWT|rcsb pdb:3EWV|rcsb pdb:3G43|rcsb pdb:3HR4|rcsb pdb:3O77|rcsb pdb:3O78|rcsb pdb:3OXQ|rcsb pdb:3UCT|rcsb pdb:3UCW|rcsb pdb:3UCY|rcsb pdb:4DCK|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0000165"(MAPK cascade)|rcsb pdb:2M0J|rcsb pdb:2M0K|rcsb pdb:4UMO|rcsb pdb:4V0C|go:"GO:0031982"(vesicle)|rcsb pdb:4Q5U|rcsb pdb:4UPU|reactome:R-HSA-2672351|reactome:R-HSA-418359|reactome:R-HSA-425561|reactome:R-HSA-5576892|reactome:R-HSA-5578775|reactome:R-HSA-936837|refseq:NP_001292555.1|rcsb pdb:4OVN|rcsb pdb:5COC|go:"GO:0021762"(substantia nigra development)|go:"GO:0070062"(extracellular exosome)|rcsb pdb:4BW7|rcsb pdb:4BW8|rcsb pdb:4L79|rcsb pdb:5DBR|rcsb pdb:4DJC|rcsb pdb:2M55|rcsb pdb:2LL7|go:"GO:0019855"(calcium channel inhibitor activity)|go:"GO:0001975"(response to amphetamine)|go:"GO:0007190"(activation of adenylate cyclase activity)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030426"(growth cone)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051412"(response to corticosterone)|go:"GO:1901841"(regulation of high voltage-gated calcium channel activity)|rcsb pdb:2N77|go:"GO:0032991"(protein-containing complex)|go:"GO:0006479"(protein methylation)|go:"GO:0014069"(postsynaptic density)|rcsb pdb:5DSU|reactome:R-HSA-8876725|rcsb pdb:4GOW|rcsb pdb:4Q57|go:"GO:0043647"(inositol phosphate metabolic process)|go:"GO:0022400"(regulation of rhodopsin mediated signaling pathway)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031432"(titin binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0031997"(N-terminal myristoylation domain binding)|go:"GO:0043274"(phospholipase binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055117"(regulation of cardiac muscle contraction)|rcsb pdb:2MG5|go:"GO:0005088"|go:"GO:0007223"(Wnt signaling pathway, calcium modulating pathway)|go:"GO:0008440"(inositol-1,4,5-trisphosphate 3-kinase activity)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0005634"(nucleus)|rcsb pdb:4JPZ|ensembl:ENST00000272298|ensembl:ENST00000291295|ensembl:ENST00000356978|ensembl:ENST00000596362|refseq:NP_001292553.1|refseq:NP_001292554.1|rcsb pdb:4BYF|reactome:R-HSA-111932|reactome:R-HSA-111933|reactome:R-HSA-111957|reactome:R-HSA-111997|reactome:R-HSA-114608|reactome:R-HSA-1445148|reactome:R-HSA-1474151|reactome:R-HSA-180024|reactome:R-HSA-1855204|reactome:R-HSA-203615|reactome:R-HSA-2514859|reactome:R-HSA-2871809|reactome:R-HSA-4086398|reactome:R-HSA-442717|reactome:R-HSA-442729|reactome:R-HSA-442745|reactome:R-HSA-442982|reactome:R-HSA-445355|reactome:R-HSA-451308|reactome:R-HSA-5218920|reactome:R-HSA-5218921|reactome:R-HSA-5607763|reactome:R-HSA-5626467|reactome:R-HSA-5627123|reactome:R-HSA-5673001|reactome:R-HSA-70221|reactome:R-HSA-983695|ensembl:ENSG00000143933|ensembl:ENSG00000160014|ensembl:ENSG00000198668|ensembl:ENSP00000272298|ensembl:ENSP00000291295|ensembl:ENSP00000349467|ensembl:ENSP00000472141|rcsb pdb:5NIN|rcsb pdb:5VMS|rcsb pdb:5WSU|rcsb pdb:5WSV|rcsb pdb:6U39|rcsb pdb:6U3A|rcsb pdb:6U3B|rcsb pdb:6U3D|rcsb pdb:2N8J|rcsb pdb:5GGM|rcsb pdb:5J8H|reactome:R-HSA-163615|reactome:R-HSA-5210891|refseq:NP_001316851.1|refseq:NP_001316852.1|refseq:NP_001316853.1|refseq:NP_001316854.1|refseq:NP_001316855.1|rcsb pdb:2N27|rcsb pdb:5DOW|rcsb pdb:5I0I|rcsb pdb:5J03|rcsb pdb:5K7L|rcsb pdb:5K8Q|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0043388"(positive regulation of DNA binding)|dip:DIP-31794N|rcsb pdb:1UP5|rcsb pdb:5JQA|rcsb pdb:5JTH|rcsb pdb:5OEO|rcsb pdb:5TP5|rcsb pdb:5TP6|rcsb pdb:5V02|rcsb pdb:5V03|rcsb pdb:5V7X|rcsb pdb:5WBX|rcsb pdb:5WC5|rcsb pdb:6B8L|rcsb pdb:6B8M|rcsb pdb:6B8N|rcsb pdb:6B8P|rcsb pdb:6B8Q|rcsb pdb:6C1D|rcsb pdb:6C1G|rcsb pdb:6C1H|rcsb pdb:6CNM|rcsb pdb:6CNN|rcsb pdb:6CNO|rcsb pdb:6FEG|rcsb pdb:6FEH|reactome:R-HSA-2025928|reactome:R-HSA-2151201|go:"GO:0034704"(calcium channel complex)|go:"GO:0010856"(adenylate cyclase activator activity)|go:"GO:0051186"(obsolete cofactor metabolic process)|go:"GO:0075206"(obsolete positive regulation by host of symbiont cAMP-mediated signal transduction)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|interpro:IPR039030|go:"GO:1902494"(catalytic complex)|go:"GO:0043234"|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0030819"(obsolete positive regulation of cAMP biosynthetic process)|rcsb pdb:6BUT|rcsb pdb:6DAD|rcsb pdb:6DAE|rcsb pdb:6DAF|rcsb pdb:6DAH|rcsb pdb:6E2F|rcsb pdb:6E2G|rcsb pdb:6EEB|rcsb pdb:6GDK|rcsb pdb:6GDL|rcsb pdb:6HCS|rcsb pdb:6JI8|rcsb pdb:6JII|rcsb pdb:6JIU|rcsb pdb:6JIY|rcsb pdb:6JRS|rcsb pdb:6JV2|rcsb pdb:6K4K|rcsb pdb:6K4L|rcsb pdb:6K4R|rcsb pdb:6MUD|rcsb pdb:6MUE|rcsb pdb:6N5W|rcsb pdb:6O5G|reactome:R-HSA-438066|reactome:R-HSA-442720|reactome:R-HSA-5673000|reactome:R-HSA-6802946|reactome:R-HSA-6802949|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9009391|reactome:R-HSA-9022535|reactome:R-HSA-9022692|reactome:R-HSA-9617324|reactome:R-HSA-9619229|reactome:R-HSA-9619483|reactome:R-HSA-9620244|go:"GO:0019722"(calcium-mediated signaling)|rcsb pdb:6PBX|rcsb pdb:6PBY|reactome:R-HSA-9649948|go:"GO:0005623"(obsolete cell)|rcsb pdb:6HR1|rcsb pdb:6OS4|rcsb pdb:6Y4P|rcsb pdb:6Y94|rcsb pdb:6Y95|reactome:R-HSA-9664323|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0016032"(viral process)|rcsb pdb:6M7H|rcsb pdb:6UZZ|rcsb pdb:6V00|rcsb pdb:6V01|rcsb pdb:6PLM|rcsb pdb:6S5T|rcsb pdb:6SZ5|rcsb pdb:6XXF|rcsb pdb:6Y4O refseq:NP_001310498.1|refseq:NP_001185951.2|refseq:NP_001310499.1|refseq:NP_001310500.1|refseq:NP_001310501.1|refseq:NP_055526.4|refseq:XP_011544293.1|refseq:XP_011544294.1|refseq:XP_016879397.1|dip:DIP-39892N|ensembl:ENSG00000103540(gene)|ensembl:ENST00000381396(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007099"(centriole replication)|go:"GO:0032053"(ciliary basal body organization)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0051298"(centrosome duplication)|go:"GO:1902018"(negative regulation of cilium assembly)|go:"GO:1903723"(negative regulation of centriole elongation)|interpro:IPR033207|mint:O43303|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5689880|reactome:R-HSA-8854518|reactome:R-HSA-9013424 - - - figure legend:1E|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/05/03 2016/05/03 rogid:tTYcOd9bOh211njZVz7cYVybAMQ9606 rogid:Gvda4RoDRcY+G50iRW5T+haubps9606 rigid:DHoJY9Z7HUKDG6HeuAMOYLkKooU false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P62158 uniprotkb:O95613 intact:EBI-397435|uniprotkb:P02593|uniprotkb:P70667|uniprotkb:P99014|uniprotkb:Q13942|uniprotkb:Q53S29|uniprotkb:Q61379|uniprotkb:Q61380|uniprotkb:Q96HK3|uniprotkb:P0DP25|uniprotkb:P0DP24|uniprotkb:P0DP23 intact:EBI-530012|uniprotkb:O43152|uniprotkb:Q7Z7C9|intact:EBI-28971202|ensembl:ENSP00000352572 psi-mi:calm_human(display_long)|uniprotkb:CALM1(gene name)|psi-mi:CALM1(display_short)|uniprotkb:CALM(gene name synonym)|uniprotkb:CAM(gene name synonym)|uniprotkb:CAM1(gene name synonym)|uniprotkb:CALM2(gene name)|psi-mi:CALM2(display_short)|uniprotkb:CAMB(gene name synonym)|uniprotkb:CALM3(gene name)|psi-mi:CALM3(display_short)|uniprotkb:CAM3(gene name synonym)|uniprotkb:CAMC(gene name synonym)|uniprotkb:CAMIII(gene name synonym)|uniprotkb:CAM2(gene name synonym)|uniprotkb:CALML2(gene name synonym) psi-mi:pcnt_human(display_long)|uniprotkb:Pericentrin-B(gene name synonym)|uniprotkb:Kendrin(gene name synonym)|uniprotkb:PCNT(gene name)|psi-mi:PCNT(display_short)|uniprotkb:KIAA0402(gene name synonym)|uniprotkb:PCNT2(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Tsang et al. (2008) pubmed:18694559|imex:IM-25243 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-11692589|imex:IM-25243-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:3SUI|rcsb pdb:2LGF|rcsb pdb:2LQC|rcsb pdb:2LQP|rcsb pdb:2Y4V|rcsb pdb:4JQ0|rcsb pdb:4LZX|rcsb pdb:4M1L|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|rcsb pdb:3J41|rcsb pdb:2LL6|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0030017"(sarcomere)|go:"GO:0030801"(obsolete positive regulation of cyclic nucleotide metabolic process)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0051343"(positive regulation of cyclic-nucleotide phosphodiesterase activity)|go:"GO:0072542"(protein phosphatase activator activity)|go:"GO:1901844"(regulation of cell communication by electrical coupling involved in cardiac conduction)|rcsb pdb:2LV6|rcsb pdb:2N6A|refseq:NP_001734.1|refseq:NP_005175.2|refseq:NP_008819.1|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005876"(spindle microtubule)|go:"GO:0000922"(spindle pole)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005980"(glycogen catabolic process)|go:"GO:0006936"(muscle contraction)|go:"GO:0060315"(negative regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0002576"(platelet degranulation)|go:"GO:0060316"(positive regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0050999"(regulation of nitric-oxide synthase activity)|rcsb pdb:1AJI|rcsb pdb:1CDL|rcsb pdb:1CLL|rcsb pdb:1CTR|rcsb pdb:1IWQ|rcsb pdb:1J7O|rcsb pdb:1J7P|rcsb pdb:1K90|rcsb pdb:1K93|rcsb pdb:1L7Z|rcsb pdb:1LVC|rcsb pdb:1NKF|rcsb pdb:1PK0|rcsb pdb:1S26|rcsb pdb:1SK6|rcsb pdb:1SW8|rcsb pdb:1WRZ|rcsb pdb:1XFU|rcsb pdb:1XFV|rcsb pdb:1XFW|rcsb pdb:1XFX|rcsb pdb:1XFY|rcsb pdb:1XFZ|rcsb pdb:1Y6W|rcsb pdb:1YR5|rcsb pdb:1YRT|rcsb pdb:1YRU|rcsb pdb:1ZOT|rcsb pdb:1ZUZ|rcsb pdb:2BE6|rcsb pdb:2F3Y|rcsb pdb:2F3Z|rcsb pdb:2HF5|rcsb pdb:2I08|rcsb pdb:2JZI|rcsb pdb:2K0E|rcsb pdb:2K0F|rcsb pdb:2K0J|rcsb pdb:2K61|rcsb pdb:2KNE|rcsb pdb:2KUG|rcsb pdb:2KUH|rcsb pdb:2L53|rcsb pdb:2L7L|rcsb pdb:2R28|rcsb pdb:2V01|rcsb pdb:2V02|rcsb pdb:2VAY|rcsb pdb:2W73|rcsb pdb:2WEL|rcsb pdb:2X0G|rcsb pdb:3BYA|rcsb pdb:3DVE|rcsb pdb:3DVJ|rcsb pdb:3DVK|rcsb pdb:3DVM|rcsb pdb:3EWT|rcsb pdb:3EWV|rcsb pdb:3G43|rcsb pdb:3HR4|rcsb pdb:3O77|rcsb pdb:3O78|rcsb pdb:3OXQ|rcsb pdb:3UCT|rcsb pdb:3UCW|rcsb pdb:3UCY|rcsb pdb:4DCK|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0000165"(MAPK cascade)|rcsb pdb:2M0J|rcsb pdb:2M0K|rcsb pdb:4UMO|rcsb pdb:4V0C|go:"GO:0031982"(vesicle)|rcsb pdb:4Q5U|rcsb pdb:4UPU|reactome:R-HSA-2672351|reactome:R-HSA-418359|reactome:R-HSA-425561|reactome:R-HSA-5576892|reactome:R-HSA-5578775|reactome:R-HSA-936837|refseq:NP_001292555.1|rcsb pdb:4OVN|rcsb pdb:5COC|go:"GO:0021762"(substantia nigra development)|go:"GO:0070062"(extracellular exosome)|rcsb pdb:4BW7|rcsb pdb:4BW8|rcsb pdb:4L79|rcsb pdb:5DBR|rcsb pdb:4DJC|rcsb pdb:2M55|rcsb pdb:2LL7|go:"GO:0019855"(calcium channel inhibitor activity)|go:"GO:0001975"(response to amphetamine)|go:"GO:0007190"(activation of adenylate cyclase activity)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030426"(growth cone)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051412"(response to corticosterone)|go:"GO:1901841"(regulation of high voltage-gated calcium channel activity)|rcsb pdb:2N77|go:"GO:0032991"(protein-containing complex)|go:"GO:0006479"(protein methylation)|go:"GO:0014069"(postsynaptic density)|rcsb pdb:5DSU|reactome:R-HSA-8876725|rcsb pdb:4GOW|rcsb pdb:4Q57|go:"GO:0043647"(inositol phosphate metabolic process)|go:"GO:0022400"(regulation of rhodopsin mediated signaling pathway)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031432"(titin binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0031997"(N-terminal myristoylation domain binding)|go:"GO:0043274"(phospholipase binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055117"(regulation of cardiac muscle contraction)|rcsb pdb:2MG5|go:"GO:0005088"|go:"GO:0007223"(Wnt signaling pathway, calcium modulating pathway)|go:"GO:0008440"(inositol-1,4,5-trisphosphate 3-kinase activity)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0005634"(nucleus)|rcsb pdb:4JPZ|ensembl:ENST00000272298|ensembl:ENST00000291295|ensembl:ENST00000356978|ensembl:ENST00000596362|refseq:NP_001292553.1|refseq:NP_001292554.1|rcsb pdb:4BYF|reactome:R-HSA-111932|reactome:R-HSA-111933|reactome:R-HSA-111957|reactome:R-HSA-111997|reactome:R-HSA-114608|reactome:R-HSA-1445148|reactome:R-HSA-1474151|reactome:R-HSA-180024|reactome:R-HSA-1855204|reactome:R-HSA-203615|reactome:R-HSA-2514859|reactome:R-HSA-2871809|reactome:R-HSA-4086398|reactome:R-HSA-442717|reactome:R-HSA-442729|reactome:R-HSA-442745|reactome:R-HSA-442982|reactome:R-HSA-445355|reactome:R-HSA-451308|reactome:R-HSA-5218920|reactome:R-HSA-5218921|reactome:R-HSA-5607763|reactome:R-HSA-5626467|reactome:R-HSA-5627123|reactome:R-HSA-5673001|reactome:R-HSA-70221|reactome:R-HSA-983695|ensembl:ENSG00000143933|ensembl:ENSG00000160014|ensembl:ENSG00000198668|ensembl:ENSP00000272298|ensembl:ENSP00000291295|ensembl:ENSP00000349467|ensembl:ENSP00000472141|rcsb pdb:5NIN|rcsb pdb:5VMS|rcsb pdb:5WSU|rcsb pdb:5WSV|rcsb pdb:6U39|rcsb pdb:6U3A|rcsb pdb:6U3B|rcsb pdb:6U3D|rcsb pdb:2N8J|rcsb pdb:5GGM|rcsb pdb:5J8H|reactome:R-HSA-163615|reactome:R-HSA-5210891|refseq:NP_001316851.1|refseq:NP_001316852.1|refseq:NP_001316853.1|refseq:NP_001316854.1|refseq:NP_001316855.1|rcsb pdb:2N27|rcsb pdb:5DOW|rcsb pdb:5I0I|rcsb pdb:5J03|rcsb pdb:5K7L|rcsb pdb:5K8Q|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0043388"(positive regulation of DNA binding)|dip:DIP-31794N|rcsb pdb:1UP5|rcsb pdb:5JQA|rcsb pdb:5JTH|rcsb pdb:5OEO|rcsb pdb:5TP5|rcsb pdb:5TP6|rcsb pdb:5V02|rcsb pdb:5V03|rcsb pdb:5V7X|rcsb pdb:5WBX|rcsb pdb:5WC5|rcsb pdb:6B8L|rcsb pdb:6B8M|rcsb pdb:6B8N|rcsb pdb:6B8P|rcsb pdb:6B8Q|rcsb pdb:6C1D|rcsb pdb:6C1G|rcsb pdb:6C1H|rcsb pdb:6CNM|rcsb pdb:6CNN|rcsb pdb:6CNO|rcsb pdb:6FEG|rcsb pdb:6FEH|reactome:R-HSA-2025928|reactome:R-HSA-2151201|go:"GO:0034704"(calcium channel complex)|go:"GO:0010856"(adenylate cyclase activator activity)|go:"GO:0051186"(obsolete cofactor metabolic process)|go:"GO:0075206"(obsolete positive regulation by host of symbiont cAMP-mediated signal transduction)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|interpro:IPR039030|go:"GO:1902494"(catalytic complex)|go:"GO:0043234"|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0030819"(obsolete positive regulation of cAMP biosynthetic process)|rcsb pdb:6BUT|rcsb pdb:6DAD|rcsb pdb:6DAE|rcsb pdb:6DAF|rcsb pdb:6DAH|rcsb pdb:6E2F|rcsb pdb:6E2G|rcsb pdb:6EEB|rcsb pdb:6GDK|rcsb pdb:6GDL|rcsb pdb:6HCS|rcsb pdb:6JI8|rcsb pdb:6JII|rcsb pdb:6JIU|rcsb pdb:6JIY|rcsb pdb:6JRS|rcsb pdb:6JV2|rcsb pdb:6K4K|rcsb pdb:6K4L|rcsb pdb:6K4R|rcsb pdb:6MUD|rcsb pdb:6MUE|rcsb pdb:6N5W|rcsb pdb:6O5G|reactome:R-HSA-438066|reactome:R-HSA-442720|reactome:R-HSA-5673000|reactome:R-HSA-6802946|reactome:R-HSA-6802949|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9009391|reactome:R-HSA-9022535|reactome:R-HSA-9022692|reactome:R-HSA-9617324|reactome:R-HSA-9619229|reactome:R-HSA-9619483|reactome:R-HSA-9620244|go:"GO:0019722"(calcium-mediated signaling)|rcsb pdb:6PBX|rcsb pdb:6PBY|reactome:R-HSA-9649948|go:"GO:0005623"(obsolete cell)|rcsb pdb:6HR1|rcsb pdb:6OS4|rcsb pdb:6Y4P|rcsb pdb:6Y94|rcsb pdb:6Y95|reactome:R-HSA-9664323|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0016032"(viral process)|rcsb pdb:6M7H|rcsb pdb:6UZZ|rcsb pdb:6V00|rcsb pdb:6V01|rcsb pdb:6PLM|rcsb pdb:6S5T|rcsb pdb:6SZ5|rcsb pdb:6XXF|rcsb pdb:6Y4O ensembl:ENSP00000352572|refseq:NP_006022.3|refseq:NP_001302458.1|ensembl:ENSG00000160299(gene)|ensembl:ENST00000359568(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0034451"(centriolar satellite)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0090316"(positive regulation of intracellular protein transport)|interpro:IPR019528|interpro:IPR028745|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|reactome:R-HSA-9613829|reactome:R-HSA-9615710|reactome:R-HSA-9646399|dip:DIP-33829N - - - figure legend:1E|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2016/05/03 2016/05/03 rogid:tTYcOd9bOh211njZVz7cYVybAMQ9606 rogid:8YHnOQE3b77ocsel2oAdsqvE+js9606 rigid:DHoJY9Z7HUKDG6HeuAMOYLkKooU false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q6A078 uniprotkb:P55258 intact:EBI-1811999|uniprotkb:Q8BIB8|ensembl:ENSMUSP00000151712 intact:EBI-398411|uniprotkb:Q8VCF6|ensembl:ENSMUSP00000003121 psi-mi:ce290_mouse(display_long)|uniprotkb:Cep290(gene name)|psi-mi:Cep290(display_short)|uniprotkb:Kiaa0373(gene name synonym)|uniprotkb:Nphp6(gene name synonym)|uniprotkb:Nephrocystin-6(gene name synonym)|uniprotkb:Bardet-Biedl syndrome 14 protein homolog(gene name synonym) psi-mi:rab8a_mouse(display_long)|uniprotkb:Rab8a(gene name)|psi-mi:Rab8a(display_short)|uniprotkb:Mel(gene name synonym)|uniprotkb:Rab8(gene name synonym)|uniprotkb:Oncogene c-mel(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Tsang et al. (2008) pubmed:18694559|imex:IM-25243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-11692772|imex:IM-25243-18 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006513591.1|refseq:NP_666121.2|dip:DIP-46317N|ensembl:ENSMUSG00000019971(gene)|ensembl:ENSMUST00000219765(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001822"(kidney development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007507"(heart development)|go:"GO:0015031"(protein transport)|go:"GO:0030902"(hindbrain development)|go:"GO:0030916"(otic vesicle formation)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048793"(pronephros development)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060271"(cilium assembly)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0097711"(ciliary basal body-plasma membrane docking)|go:"GO:0120200"(rod photoreceptor outer segment)|go:"GO:0120205"(photoreceptor proximal connecting cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1905349"(ciliary transition zone assembly)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR026201|interpro:IPR032321|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-6798695|reactome:R-MMU-8854518 refseq:NP_075615.2|dip:DIP-31053N|ensembl:ENSMUSG00000003037(gene)|ensembl:ENSMUST00000003121(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0007409"(axonogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0009306"(protein secretion)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0014069"(postsynaptic density)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019003"(GDP binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0030425"(dendrite)|go:"GO:0030496"(midbody)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031489"(myosin V binding)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0045202"(synapse)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0048210"(Golgi vesicle fusion to target membrane)|go:"GO:0051223"(regulation of protein transport)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098969"(neurotransmitter receptor transport to postsynaptic membrane)|go:"GO:0099003"(vesicle-mediated transport in synapse)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P55258|rcsb pdb:2FU5|reactome:R-MMU-2565942|reactome:R-MMU-5620912|reactome:R-MMU-5620916|reactome:R-MMU-8854214|reactome:R-MMU-8873719|reactome:R-MMU-8876198|go:"GO:0098978"(glutamatergic synapse) - - - figure legend:5D|antagonist:cell quiescence. Less CPP110 associated in quiescent compared to growing cells.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-nih_3t3)|taxid:10090(Mus musculus Swiss NIH 3t3 embryo fibroblast cells) - 2016/05/03 2016/05/04 rogid:6XYc7XLCqfq0g5xaB5l4amJnFT410090 rogid:SE+1h+U6C8cAN2UTBIDapsUt4zA10090 rigid:zOkbKmZ/q2EfS9tiYkSMcf1tvWQ false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q6A078 uniprotkb:Q7TSH4 intact:EBI-1811999|uniprotkb:Q8BIB8|ensembl:ENSMUSP00000151712 intact:EBI-646843|uniprotkb:Q6A072|ensembl:ENSMUSP00000038881|ensembl:ENSMUSP00000102167 psi-mi:ce290_mouse(display_long)|uniprotkb:Cep290(gene name)|psi-mi:Cep290(display_short)|uniprotkb:Kiaa0373(gene name synonym)|uniprotkb:Nphp6(gene name synonym)|uniprotkb:Nephrocystin-6(gene name synonym)|uniprotkb:Bardet-Biedl syndrome 14 protein homolog(gene name synonym) psi-mi:cp110_mouse(display_long)|uniprotkb:Cep110(gene name synonym)|uniprotkb:Ccp110(gene name)|psi-mi:Ccp110(display_short)|uniprotkb:Kiaa0419(gene name synonym)|uniprotkb:Cp110(gene name synonym)|uniprotkb:Centrosomal protein of 110 kDa(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Tsang et al. (2008) pubmed:18694559|imex:IM-25243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-11692772|imex:IM-25243-18 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006513591.1|refseq:NP_666121.2|dip:DIP-46317N|ensembl:ENSMUSG00000019971(gene)|ensembl:ENSMUST00000219765(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001822"(kidney development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007507"(heart development)|go:"GO:0015031"(protein transport)|go:"GO:0030902"(hindbrain development)|go:"GO:0030916"(otic vesicle formation)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048793"(pronephros development)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060271"(cilium assembly)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0097711"(ciliary basal body-plasma membrane docking)|go:"GO:0120200"(rod photoreceptor outer segment)|go:"GO:0120205"(photoreceptor proximal connecting cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1905349"(ciliary transition zone assembly)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR026201|interpro:IPR032321|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-6798695|reactome:R-MMU-8854518 refseq:NP_892040.1|ensembl:ENSMUSG00000033904(gene)|ensembl:ENSMUST00000038650(transcript)|ensembl:ENSMUST00000106557(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005929"(cilium)|go:"GO:0007099"(centriole replication)|go:"GO:0032053"(ciliary basal body organization)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0051298"(centrosome duplication)|go:"GO:1902018"(negative regulation of cilium assembly)|go:"GO:1903723"(negative regulation of centriole elongation)|interpro:IPR033207|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-5689880|reactome:R-MMU-8854518|reactome:R-MMU-9013424 - - - figure legend:5D|antagonist:cell quiescence. Less CPP110 associated in quiescent compared to growing cells.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-nih_3t3)|taxid:10090(Mus musculus Swiss NIH 3t3 embryo fibroblast cells) - 2016/05/03 2016/05/04 rogid:6XYc7XLCqfq0g5xaB5l4amJnFT410090 rogid:Ma+OC215nDGgK9D4XMR9h7X4EV410090 rigid:zOkbKmZ/q2EfS9tiYkSMcf1tvWQ false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P55258 uniprotkb:Q6A078 intact:EBI-398411|uniprotkb:Q8VCF6|ensembl:ENSMUSP00000003121 intact:EBI-1811999|uniprotkb:Q8BIB8|ensembl:ENSMUSP00000151712 psi-mi:rab8a_mouse(display_long)|uniprotkb:Rab8a(gene name)|psi-mi:Rab8a(display_short)|uniprotkb:Mel(gene name synonym)|uniprotkb:Rab8(gene name synonym)|uniprotkb:Oncogene c-mel(gene name synonym) psi-mi:ce290_mouse(display_long)|uniprotkb:Cep290(gene name)|psi-mi:Cep290(display_short)|uniprotkb:Kiaa0373(gene name synonym)|uniprotkb:Nphp6(gene name synonym)|uniprotkb:Nephrocystin-6(gene name synonym)|uniprotkb:Bardet-Biedl syndrome 14 protein homolog(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Tsang et al. (2008) pubmed:18694559|imex:IM-25243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-11692778|imex:IM-25243-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_075615.2|dip:DIP-31053N|ensembl:ENSMUSG00000003037(gene)|ensembl:ENSMUST00000003121(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0007409"(axonogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0009306"(protein secretion)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0014069"(postsynaptic density)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019003"(GDP binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0030425"(dendrite)|go:"GO:0030496"(midbody)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031489"(myosin V binding)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0045202"(synapse)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0048210"(Golgi vesicle fusion to target membrane)|go:"GO:0051223"(regulation of protein transport)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098969"(neurotransmitter receptor transport to postsynaptic membrane)|go:"GO:0099003"(vesicle-mediated transport in synapse)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P55258|rcsb pdb:2FU5|reactome:R-MMU-2565942|reactome:R-MMU-5620912|reactome:R-MMU-5620916|reactome:R-MMU-8854214|reactome:R-MMU-8873719|reactome:R-MMU-8876198|go:"GO:0098978"(glutamatergic synapse) refseq:XP_006513591.1|refseq:NP_666121.2|dip:DIP-46317N|ensembl:ENSMUSG00000019971(gene)|ensembl:ENSMUST00000219765(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001822"(kidney development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007507"(heart development)|go:"GO:0015031"(protein transport)|go:"GO:0030902"(hindbrain development)|go:"GO:0030916"(otic vesicle formation)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048793"(pronephros development)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060271"(cilium assembly)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0097711"(ciliary basal body-plasma membrane docking)|go:"GO:0120200"(rod photoreceptor outer segment)|go:"GO:0120205"(photoreceptor proximal connecting cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1905349"(ciliary transition zone assembly)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR026201|interpro:IPR032321|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-6798695|reactome:R-MMU-8854518 - - - figure legend:5D|antagonist:cell quiescence. No CPP110 associated in quiescent compared to growing cells.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-nih_3t3)|taxid:10090(Mus musculus Swiss NIH 3t3 embryo fibroblast cells) - 2016/05/03 2016/05/04 rogid:SE+1h+U6C8cAN2UTBIDapsUt4zA10090 rogid:6XYc7XLCqfq0g5xaB5l4amJnFT410090 rigid:zOkbKmZ/q2EfS9tiYkSMcf1tvWQ false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P55258 uniprotkb:Q7TSH4 intact:EBI-398411|uniprotkb:Q8VCF6|ensembl:ENSMUSP00000003121 intact:EBI-646843|uniprotkb:Q6A072|ensembl:ENSMUSP00000038881|ensembl:ENSMUSP00000102167 psi-mi:rab8a_mouse(display_long)|uniprotkb:Rab8a(gene name)|psi-mi:Rab8a(display_short)|uniprotkb:Mel(gene name synonym)|uniprotkb:Rab8(gene name synonym)|uniprotkb:Oncogene c-mel(gene name synonym) psi-mi:cp110_mouse(display_long)|uniprotkb:Cep110(gene name synonym)|uniprotkb:Ccp110(gene name)|psi-mi:Ccp110(display_short)|uniprotkb:Kiaa0419(gene name synonym)|uniprotkb:Cp110(gene name synonym)|uniprotkb:Centrosomal protein of 110 kDa(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Tsang et al. (2008) pubmed:18694559|imex:IM-25243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-11692778|imex:IM-25243-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_075615.2|dip:DIP-31053N|ensembl:ENSMUSG00000003037(gene)|ensembl:ENSMUST00000003121(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0007409"(axonogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0009306"(protein secretion)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0014069"(postsynaptic density)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019003"(GDP binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0030425"(dendrite)|go:"GO:0030496"(midbody)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031489"(myosin V binding)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0045202"(synapse)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0048210"(Golgi vesicle fusion to target membrane)|go:"GO:0051223"(regulation of protein transport)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098969"(neurotransmitter receptor transport to postsynaptic membrane)|go:"GO:0099003"(vesicle-mediated transport in synapse)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P55258|rcsb pdb:2FU5|reactome:R-MMU-2565942|reactome:R-MMU-5620912|reactome:R-MMU-5620916|reactome:R-MMU-8854214|reactome:R-MMU-8873719|reactome:R-MMU-8876198|go:"GO:0098978"(glutamatergic synapse) refseq:NP_892040.1|ensembl:ENSMUSG00000033904(gene)|ensembl:ENSMUST00000038650(transcript)|ensembl:ENSMUST00000106557(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005929"(cilium)|go:"GO:0007099"(centriole replication)|go:"GO:0032053"(ciliary basal body organization)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0051298"(centrosome duplication)|go:"GO:1902018"(negative regulation of cilium assembly)|go:"GO:1903723"(negative regulation of centriole elongation)|interpro:IPR033207|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-5689880|reactome:R-MMU-8854518|reactome:R-MMU-9013424 - - - figure legend:5D|antagonist:cell quiescence. No CPP110 associated in quiescent compared to growing cells.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-nih_3t3)|taxid:10090(Mus musculus Swiss NIH 3t3 embryo fibroblast cells) - 2016/05/03 2016/05/04 rogid:SE+1h+U6C8cAN2UTBIDapsUt4zA10090 rogid:Ma+OC215nDGgK9D4XMR9h7X4EV410090 rigid:zOkbKmZ/q2EfS9tiYkSMcf1tvWQ false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q6A078 uniprotkb:Q7TSH4 intact:EBI-1811999|uniprotkb:Q8BIB8|ensembl:ENSMUSP00000151712 intact:EBI-646843|uniprotkb:Q6A072|ensembl:ENSMUSP00000038881|ensembl:ENSMUSP00000102167 psi-mi:ce290_mouse(display_long)|uniprotkb:Cep290(gene name)|psi-mi:Cep290(display_short)|uniprotkb:Kiaa0373(gene name synonym)|uniprotkb:Nphp6(gene name synonym)|uniprotkb:Nephrocystin-6(gene name synonym)|uniprotkb:Bardet-Biedl syndrome 14 protein homolog(gene name synonym) psi-mi:cp110_mouse(display_long)|uniprotkb:Cep110(gene name synonym)|uniprotkb:Ccp110(gene name)|psi-mi:Ccp110(display_short)|uniprotkb:Kiaa0419(gene name synonym)|uniprotkb:Cp110(gene name synonym)|uniprotkb:Centrosomal protein of 110 kDa(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Tsang et al. (2008) pubmed:18694559|imex:IM-25243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-11692784|imex:IM-25243-20 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006513591.1|refseq:NP_666121.2|dip:DIP-46317N|ensembl:ENSMUSG00000019971(gene)|ensembl:ENSMUST00000219765(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001822"(kidney development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007507"(heart development)|go:"GO:0015031"(protein transport)|go:"GO:0030902"(hindbrain development)|go:"GO:0030916"(otic vesicle formation)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048793"(pronephros development)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060271"(cilium assembly)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0097711"(ciliary basal body-plasma membrane docking)|go:"GO:0120200"(rod photoreceptor outer segment)|go:"GO:0120205"(photoreceptor proximal connecting cilium)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1905349"(ciliary transition zone assembly)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR026201|interpro:IPR032321|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-6798695|reactome:R-MMU-8854518 refseq:NP_892040.1|ensembl:ENSMUSG00000033904(gene)|ensembl:ENSMUST00000038650(transcript)|ensembl:ENSMUST00000106557(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005929"(cilium)|go:"GO:0007099"(centriole replication)|go:"GO:0032053"(ciliary basal body organization)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0051298"(centrosome duplication)|go:"GO:1902018"(negative regulation of cilium assembly)|go:"GO:1903723"(negative regulation of centriole elongation)|interpro:IPR033207|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-5689880|reactome:R-MMU-8854518|reactome:R-MMU-9013424 - - - figure legend:5D|comment:in growing cells|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-nih_3t3)|taxid:10090(Mus musculus Swiss NIH 3t3 embryo fibroblast cells) - 2016/05/03 2016/05/12 rogid:6XYc7XLCqfq0g5xaB5l4amJnFT410090 rogid:Ma+OC215nDGgK9D4XMR9h7X4EV410090 rigid:Axa+k+IwBYnoIHo3QJRWxB7jt9M false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O15078 uniprotkb:Q12798 intact:EBI-1811944|uniprotkb:Q1PSK5|uniprotkb:Q66GS8|uniprotkb:Q9H2G6|uniprotkb:Q9H6Q7|uniprotkb:Q9H8I0|ensembl:ENSP00000448012 intact:EBI-2512818|ensembl:ENSP00000319052|uniprotkb:B2R536 psi-mi:ce290_human(display_long)|uniprotkb:CEP290(gene name)|psi-mi:CEP290(display_short)|uniprotkb:KIAA0373(gene name synonym)|uniprotkb:NPHP6(gene name synonym)|uniprotkb:Nephrocystin-6(gene name synonym)|uniprotkb:Tumor antigen se2-2(gene name synonym)|uniprotkb:Cancer/testis antigen 87(gene name synonym)|uniprotkb:BBS14(gene name synonym)|uniprotkb:Bardet-Biedl syndrome 14 protein(gene name synonym) psi-mi:cetn1_human(display_long)|uniprotkb:CETN1(gene name)|psi-mi:CETN1(display_short)|uniprotkb:CEN1(gene name synonym)|uniprotkb:CETN(gene name synonym)|uniprotkb:Caltractin isoform 2(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Tsang et al. (2008) pubmed:18694559|imex:IM-25243 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-11692817|imex:IM-25243-22 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079390.3|dip:DIP-46541N|ensembl:ENSG00000198707(gene)|ensembl:ENST00000552810(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0030902"(hindbrain development)|go:"GO:0030916"(otic vesicle formation)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035580"(specific granule lumen)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048793"(pronephros development)|go:"GO:0060271"(cilium assembly)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0097711"(ciliary basal body-plasma membrane docking)|go:"GO:1905349"(ciliary transition zone assembly)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR026201|interpro:IPR032321|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-6798695|reactome:R-HSA-8854518 ensembl:ENSG00000177143(gene)|ensembl:ENST00000327228(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0007099"(centriole replication)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0051301"(cell division)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR029527|reactome:R-HSA-9613829|reactome:R-HSA-9615710|reactome:R-HSA-9646399|refseq:NP_004057.1 go:"GO:0005814"(centriole) - - figure legend:supplemental S1C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2016/05/03 2016/05/04 rogid:89HbDVs4UVmzftFFLO/pHklTiUQ9606 rogid:uZs9mMo7OXGTDDaadTQGyV/v0iM9606 rigid:rQjWXsuc/WCjJHO+twJhQttpuzk false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:O15078 uniprotkb:O43303 intact:EBI-1811944|uniprotkb:Q1PSK5|uniprotkb:Q66GS8|uniprotkb:Q9H2G6|uniprotkb:Q9H6Q7|uniprotkb:Q9H8I0|ensembl:ENSP00000448012 intact:EBI-1566217|uniprotkb:O43335|uniprotkb:Q68DV9|uniprotkb:Q8NE13|uniprotkb:B7WP23|ensembl:ENSP00000370803 psi-mi:ce290_human(display_long)|uniprotkb:CEP290(gene name)|psi-mi:CEP290(display_short)|uniprotkb:KIAA0373(gene name synonym)|uniprotkb:NPHP6(gene name synonym)|uniprotkb:Nephrocystin-6(gene name synonym)|uniprotkb:Tumor antigen se2-2(gene name synonym)|uniprotkb:Cancer/testis antigen 87(gene name synonym)|uniprotkb:BBS14(gene name synonym)|uniprotkb:Bardet-Biedl syndrome 14 protein(gene name synonym) psi-mi:cp110_human(display_long)|uniprotkb:CP110(gene name synonym)|uniprotkb:CCP110(gene name)|psi-mi:CCP110(display_short)|uniprotkb:CEP110(gene name synonym)|uniprotkb:KIAA0419(gene name synonym)|uniprotkb:Centrosomal protein of 110 kDa(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Tsang et al. (2008) pubmed:18694559|imex:IM-25243 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-11692822|imex:IM-25243-23 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079390.3|dip:DIP-46541N|ensembl:ENSG00000198707(gene)|ensembl:ENST00000552810(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0030902"(hindbrain development)|go:"GO:0030916"(otic vesicle formation)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035580"(specific granule lumen)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048793"(pronephros development)|go:"GO:0060271"(cilium assembly)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0097711"(ciliary basal body-plasma membrane docking)|go:"GO:1905349"(ciliary transition zone assembly)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR026201|interpro:IPR032321|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-6798695|reactome:R-HSA-8854518 refseq:NP_001310498.1|refseq:NP_001185951.2|refseq:NP_001310499.1|refseq:NP_001310500.1|refseq:NP_001310501.1|refseq:NP_055526.4|refseq:XP_011544293.1|refseq:XP_011544294.1|refseq:XP_016879397.1|dip:DIP-39892N|ensembl:ENSG00000103540(gene)|ensembl:ENST00000381396(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007099"(centriole replication)|go:"GO:0032053"(ciliary basal body organization)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0051298"(centrosome duplication)|go:"GO:1902018"(negative regulation of cilium assembly)|go:"GO:1903723"(negative regulation of centriole elongation)|interpro:IPR033207|mint:O43303|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5689880|reactome:R-HSA-8854518|reactome:R-HSA-9013424 go:"GO:0005814"(centriole) - - figure legend:supplemental S1D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2016/05/03 2016/05/04 rogid:89HbDVs4UVmzftFFLO/pHklTiUQ9606 rogid:Gvda4RoDRcY+G50iRW5T+haubps9606 rigid:Mt5EJbMSbMebEHqzvQUMv9X5pjc false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining)