#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P25963	uniprotkb:P21530-PRO_0000038062	intact:EBI-307386|ensembl:ENSP00000216797|uniprotkb:B2R8L6	intact:EBI-12558622	psi-mi:ikba_human(display_long)|uniprotkb:NFKBIA(gene name)|psi-mi:NFKBIA(display_short)|uniprotkb:IKBA(gene name synonym)|uniprotkb:MAD3(gene name synonym)|uniprotkb:NFKBI(gene name synonym)|uniprotkb:I-kappa-B-alpha(gene name synonym)|uniprotkb:Major histocompatibility complex enhancer-binding protein MAD3(gene name synonym)	psi-mi:p21530-pro_0000038062(display_long)	psi-mi:"MI:0018"(two hybrid)	Doceul et al. (2008)	pubmed:18632959|imex:IM-26008	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:11098(csfvb)|taxid:11098("Classical swine fever virus (strain Brescia)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-12558620|imex:IM-26008-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000100906(gene)|ensembl:ENST00000216797(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006915"(apoptotic process)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007253"(cytoplasmic sequestering of NF-kappaB)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0010745"(negative regulation of macrophage derived foam cell differentiation)|refseq:NP_065390.1|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010888"(negative regulation of lipid storage)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0033256"(I-kappaB/NF-kappaB complex)|go:"GO:0034142"(toll-like receptor 4 signaling pathway)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0070417"(cellular response to cold)|go:"GO:0070427"(nucleotide-binding oligomerization domain containing 1 signaling pathway)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:1901222"(regulation of NIK/NF-kappaB signaling)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:P25963|rcsb pdb:1IKN|rcsb pdb:1NFI|rcsb pdb:6TTU|rcsb pdb:6Y1J|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-4755510|reactome:R-HSA-5603029|reactome:R-HSA-5607764|go:"GO:0019899"(enzyme binding)|reactome:R-HSA-5689880|reactome:R-HSA-9020702|reactome:R-HSA-933542|dip:DIP-139N	intact:EBI-9523036(chain-parent)	-	-	chain-seq-start:1|chain-seq-end:168	figure legend:results|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2016/10/11	2016/10/11	rogid:LXYgOHjWhEj5sPeyBEi9kV4ZBP89606	rogid:E8+isF/QCbF8O+au5LRoMKMQKKA11098	rigid:TJVSreUU87cYLMqCXqesBAEIR5U	false	sufficient binding region:213-317	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P25963	uniprotkb:P21530-PRO_0000038062	intact:EBI-307386|ensembl:ENSP00000216797|uniprotkb:B2R8L6	intact:EBI-12558622	psi-mi:ikba_human(display_long)|uniprotkb:NFKBIA(gene name)|psi-mi:NFKBIA(display_short)|uniprotkb:IKBA(gene name synonym)|uniprotkb:MAD3(gene name synonym)|uniprotkb:NFKBI(gene name synonym)|uniprotkb:I-kappa-B-alpha(gene name synonym)|uniprotkb:Major histocompatibility complex enhancer-binding protein MAD3(gene name synonym)	psi-mi:p21530-pro_0000038062(display_long)	psi-mi:"MI:0018"(two hybrid)	Doceul et al. (2008)	pubmed:18632959|imex:IM-26008	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:11098(csfvb)|taxid:11098("Classical swine fever virus (strain Brescia)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-12558646|imex:IM-26008-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000100906(gene)|ensembl:ENST00000216797(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006915"(apoptotic process)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007253"(cytoplasmic sequestering of NF-kappaB)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0010745"(negative regulation of macrophage derived foam cell differentiation)|refseq:NP_065390.1|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010888"(negative regulation of lipid storage)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0033256"(I-kappaB/NF-kappaB complex)|go:"GO:0034142"(toll-like receptor 4 signaling pathway)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0070417"(cellular response to cold)|go:"GO:0070427"(nucleotide-binding oligomerization domain containing 1 signaling pathway)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:1901222"(regulation of NIK/NF-kappaB signaling)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:P25963|rcsb pdb:1IKN|rcsb pdb:1NFI|rcsb pdb:6TTU|rcsb pdb:6Y1J|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-4755510|reactome:R-HSA-5603029|reactome:R-HSA-5607764|go:"GO:0019899"(enzyme binding)|reactome:R-HSA-5689880|reactome:R-HSA-9020702|reactome:R-HSA-933542|dip:DIP-139N	intact:EBI-9523036(chain-parent)	-	-	chain-seq-start:1|chain-seq-end:168	figure legend:1|comment:Full length hIkBa  was unable to interact with CSFV Npro.  .|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2016/10/11	2016/10/11	rogid:LXYgOHjWhEj5sPeyBEi9kV4ZBP89606	rogid:E8+isF/QCbF8O+au5LRoMKMQKKA11098	rigid:TJVSreUU87cYLMqCXqesBAEIR5U	false	sufficient binding region:213-317|sufficient binding region:121-317	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P25963	uniprotkb:P21530-PRO_0000038062	intact:EBI-307386|ensembl:ENSP00000216797|uniprotkb:B2R8L6	intact:EBI-12558622	psi-mi:ikba_human(display_long)|uniprotkb:NFKBIA(gene name)|psi-mi:NFKBIA(display_short)|uniprotkb:IKBA(gene name synonym)|uniprotkb:MAD3(gene name synonym)|uniprotkb:NFKBI(gene name synonym)|uniprotkb:I-kappa-B-alpha(gene name synonym)|uniprotkb:Major histocompatibility complex enhancer-binding protein MAD3(gene name synonym)	psi-mi:p21530-pro_0000038062(display_long)	psi-mi:"MI:0096"(pull down)	Doceul et al. (2008)	pubmed:18632959|imex:IM-26008	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:11098(csfvb)|taxid:11098("Classical swine fever virus (strain Brescia)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-12558670|imex:IM-26008-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000100906(gene)|ensembl:ENST00000216797(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006915"(apoptotic process)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007253"(cytoplasmic sequestering of NF-kappaB)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0010745"(negative regulation of macrophage derived foam cell differentiation)|refseq:NP_065390.1|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010888"(negative regulation of lipid storage)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0033256"(I-kappaB/NF-kappaB complex)|go:"GO:0034142"(toll-like receptor 4 signaling pathway)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0070417"(cellular response to cold)|go:"GO:0070427"(nucleotide-binding oligomerization domain containing 1 signaling pathway)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:1901222"(regulation of NIK/NF-kappaB signaling)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:P25963|rcsb pdb:1IKN|rcsb pdb:1NFI|rcsb pdb:6TTU|rcsb pdb:6Y1J|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-4755510|reactome:R-HSA-5603029|reactome:R-HSA-5607764|go:"GO:0019899"(enzyme binding)|reactome:R-HSA-5689880|reactome:R-HSA-9020702|reactome:R-HSA-933542|dip:DIP-139N	intact:EBI-9523036(chain-parent)	-	-	chain-seq-start:1|chain-seq-end:168	figure legend:2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/10/11	2016/10/11	rogid:LXYgOHjWhEj5sPeyBEi9kV4ZBP89606	rogid:E8+isF/QCbF8O+au5LRoMKMQKKA11098	rigid:TJVSreUU87cYLMqCXqesBAEIR5U	false	sufficient binding region:213-317|his tag:?-?	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q08353	uniprotkb:P21530-PRO_0000038062	intact:EBI-12558699|ensembl:ENSSSCP00000002133|ensembl:ENSSSCP00015015516|ensembl:ENSSSCP00025040620|ensembl:ENSSSCP00030037706|ensembl:ENSSSCP00035042295|ensembl:ENSSSCP00040023108|ensembl:ENSSSCP00045011831|ensembl:ENSSSCP00050003687|ensembl:ENSSSCP00055047145|ensembl:ENSSSCP00060038508|ensembl:ENSSSCP00065035456|ensembl:ENSSSCP00070011807|ensembl:ENSSSCP00070011804|uniprotkb:F2Q9A9	intact:EBI-12558622	psi-mi:ikba_pig(display_long)|uniprotkb:NFKBIA(gene name)|psi-mi:NFKBIA(display_short)|uniprotkb:IKBA(gene name synonym)|uniprotkb:ECI-6(gene name synonym)|uniprotkb:I-kappa-B-alpha(gene name synonym)	psi-mi:p21530-pro_0000038062(display_long)	psi-mi:"MI:0096"(pull down)	Doceul et al. (2008)	pubmed:18632959|imex:IM-26008	taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)")	taxid:11098(csfvb)|taxid:11098("Classical swine fever virus (strain Brescia)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-12558688|imex:IM-26008-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034142"(toll-like receptor 4 signaling pathway)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0070427"(nucleotide-binding oligomerization domain containing 1 signaling pathway)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|ensembl:ENSSSCG00000001952(gene)|ensembl:ENSSSCG00015029389(gene)|ensembl:ENSSSCG00025067390(gene)|ensembl:ENSSSCG00030058851(gene)|ensembl:ENSSSCG00035073638(gene)|ensembl:ENSSSCG00045010107(gene)|ensembl:ENSSSCG00050006268(gene)|ensembl:ENSSSCG00055029632(gene)|ensembl:ENSSSCG00060065186(gene)|ensembl:ENSSSCG00065059454(gene)|ensembl:ENSSSCG00070007418(gene)|ensembl:ENSSSCG00040041514(gene)|ensembl:ENSSSCT00000002184(transcript)|ensembl:ENSSSCT00015039015(transcript)|ensembl:ENSSSCT00025092560(transcript)|ensembl:ENSSSCT00030082138(transcript)|ensembl:ENSSSCT00035099812(transcript)|ensembl:ENSSSCT00040055590(transcript)|ensembl:ENSSSCT00045017158(transcript)|ensembl:ENSSSCT00050008579(transcript)|ensembl:ENSSSCT00055058871(transcript)|ensembl:ENSSSCT00060088999(transcript)|ensembl:ENSSSCT00065081421(transcript)|ensembl:ENSSSCT00070014299(transcript)|ensembl:ENSSSCT00070014305(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007253"(cytoplasmic sequestering of NF-kappaB)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0010745"(negative regulation of macrophage derived foam cell differentiation)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010888"(negative regulation of lipid storage)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|reactome:R-SSC-1810476|reactome:R-SSC-202424|reactome:R-SSC-209560|reactome:R-SSC-2871837|reactome:R-SSC-445989|reactome:R-SSC-5607764|reactome:R-SSC-5689880|reactome:R-SSC-9020702|reactome:R-SSC-933542|reactome:R-SSC-1169091|refseq:NP_001005150.1	intact:EBI-9523036(chain-parent)	-	-	chain-seq-start:1|chain-seq-end:168	figure legend:2 & 3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2016/10/11	2016/10/11	rogid:4WzpOxVa0CNXUWMqQsVRGsz7Mdg9823	rogid:E8+isF/QCbF8O+au5LRoMKMQKKA11098	rigid:kwMB8AyqfTLA5GBqstUanl21Kmo	false	his tag:?-?|necessary binding region:249-314	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P25963	uniprotkb:P21530-PRO_0000038062	intact:EBI-307386|ensembl:ENSP00000216797|uniprotkb:B2R8L6	intact:EBI-12558622	psi-mi:ikba_human(display_long)|uniprotkb:NFKBIA(gene name)|psi-mi:NFKBIA(display_short)|uniprotkb:IKBA(gene name synonym)|uniprotkb:MAD3(gene name synonym)|uniprotkb:NFKBI(gene name synonym)|uniprotkb:I-kappa-B-alpha(gene name synonym)|uniprotkb:Major histocompatibility complex enhancer-binding protein MAD3(gene name synonym)	psi-mi:p21530-pro_0000038062(display_long)	psi-mi:"MI:0096"(pull down)	Doceul et al. (2008)	pubmed:18632959|imex:IM-26008	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:11098(csfvb)|taxid:11098("Classical swine fever virus (strain Brescia)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-12558751|imex:IM-26008-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000100906(gene)|ensembl:ENST00000216797(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006915"(apoptotic process)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007253"(cytoplasmic sequestering of NF-kappaB)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0010745"(negative regulation of macrophage derived foam cell differentiation)|refseq:NP_065390.1|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010888"(negative regulation of lipid storage)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0033256"(I-kappaB/NF-kappaB complex)|go:"GO:0034142"(toll-like receptor 4 signaling pathway)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0070417"(cellular response to cold)|go:"GO:0070427"(nucleotide-binding oligomerization domain containing 1 signaling pathway)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:1901222"(regulation of NIK/NF-kappaB signaling)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:P25963|rcsb pdb:1IKN|rcsb pdb:1NFI|rcsb pdb:6TTU|rcsb pdb:6Y1J|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-4755510|reactome:R-HSA-5603029|reactome:R-HSA-5607764|go:"GO:0019899"(enzyme binding)|reactome:R-HSA-5689880|reactome:R-HSA-9020702|reactome:R-HSA-933542|dip:DIP-139N	intact:EBI-9523036(chain-parent)	-	-	chain-seq-start:1|chain-seq-end:168	figure legend:3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9823(pig-max)|taxid:9823(Max kidney cell line)	-	2016/10/11	2017/08/09	rogid:LXYgOHjWhEj5sPeyBEi9kV4ZBP89606	rogid:E8+isF/QCbF8O+au5LRoMKMQKKA11098	rigid:TJVSreUU87cYLMqCXqesBAEIR5U	false	sufficient binding region:213-317	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q08353	uniprotkb:P21530-PRO_0000038062	intact:EBI-12558699|ensembl:ENSSSCP00000002133|ensembl:ENSSSCP00015015516|ensembl:ENSSSCP00025040620|ensembl:ENSSSCP00030037706|ensembl:ENSSSCP00035042295|ensembl:ENSSSCP00040023108|ensembl:ENSSSCP00045011831|ensembl:ENSSSCP00050003687|ensembl:ENSSSCP00055047145|ensembl:ENSSSCP00060038508|ensembl:ENSSSCP00065035456|ensembl:ENSSSCP00070011807|ensembl:ENSSSCP00070011804|uniprotkb:F2Q9A9	intact:EBI-12558622	psi-mi:ikba_pig(display_long)|uniprotkb:NFKBIA(gene name)|psi-mi:NFKBIA(display_short)|uniprotkb:IKBA(gene name synonym)|uniprotkb:ECI-6(gene name synonym)|uniprotkb:I-kappa-B-alpha(gene name synonym)	psi-mi:p21530-pro_0000038062(display_long)	psi-mi:"MI:0096"(pull down)	Doceul et al. (2008)	pubmed:18632959|imex:IM-26008	taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)")	taxid:11098(csfvb)|taxid:11098("Classical swine fever virus (strain Brescia)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-12559374|imex:IM-26008-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034142"(toll-like receptor 4 signaling pathway)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0070427"(nucleotide-binding oligomerization domain containing 1 signaling pathway)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|ensembl:ENSSSCG00000001952(gene)|ensembl:ENSSSCG00015029389(gene)|ensembl:ENSSSCG00025067390(gene)|ensembl:ENSSSCG00030058851(gene)|ensembl:ENSSSCG00035073638(gene)|ensembl:ENSSSCG00045010107(gene)|ensembl:ENSSSCG00050006268(gene)|ensembl:ENSSSCG00055029632(gene)|ensembl:ENSSSCG00060065186(gene)|ensembl:ENSSSCG00065059454(gene)|ensembl:ENSSSCG00070007418(gene)|ensembl:ENSSSCG00040041514(gene)|ensembl:ENSSSCT00000002184(transcript)|ensembl:ENSSSCT00015039015(transcript)|ensembl:ENSSSCT00025092560(transcript)|ensembl:ENSSSCT00030082138(transcript)|ensembl:ENSSSCT00035099812(transcript)|ensembl:ENSSSCT00040055590(transcript)|ensembl:ENSSSCT00045017158(transcript)|ensembl:ENSSSCT00050008579(transcript)|ensembl:ENSSSCT00055058871(transcript)|ensembl:ENSSSCT00060088999(transcript)|ensembl:ENSSSCT00065081421(transcript)|ensembl:ENSSSCT00070014299(transcript)|ensembl:ENSSSCT00070014305(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007253"(cytoplasmic sequestering of NF-kappaB)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0010745"(negative regulation of macrophage derived foam cell differentiation)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010888"(negative regulation of lipid storage)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|reactome:R-SSC-1810476|reactome:R-SSC-202424|reactome:R-SSC-209560|reactome:R-SSC-2871837|reactome:R-SSC-445989|reactome:R-SSC-5607764|reactome:R-SSC-5689880|reactome:R-SSC-9020702|reactome:R-SSC-933542|reactome:R-SSC-1169091|refseq:NP_001005150.1	intact:EBI-9523036(chain-parent)	-	-	chain-seq-start:1|chain-seq-end:168	figure legend:3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9823(pig-max)|taxid:9823(Max kidney cell line)	-	2016/10/11	2017/08/09	rogid:4WzpOxVa0CNXUWMqQsVRGsz7Mdg9823	rogid:E8+isF/QCbF8O+au5LRoMKMQKKA11098	rigid:kwMB8AyqfTLA5GBqstUanl21Kmo	false	-	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q08353	uniprotkb:P21530-PRO_0000038062	intact:EBI-12558699|ensembl:ENSSSCP00000002133|ensembl:ENSSSCP00015015516|ensembl:ENSSSCP00025040620|ensembl:ENSSSCP00030037706|ensembl:ENSSSCP00035042295|ensembl:ENSSSCP00040023108|ensembl:ENSSSCP00045011831|ensembl:ENSSSCP00050003687|ensembl:ENSSSCP00055047145|ensembl:ENSSSCP00060038508|ensembl:ENSSSCP00065035456|ensembl:ENSSSCP00070011807|ensembl:ENSSSCP00070011804|uniprotkb:F2Q9A9	intact:EBI-12558622	psi-mi:ikba_pig(display_long)|uniprotkb:NFKBIA(gene name)|psi-mi:NFKBIA(display_short)|uniprotkb:IKBA(gene name synonym)|uniprotkb:ECI-6(gene name synonym)|uniprotkb:I-kappa-B-alpha(gene name synonym)	psi-mi:p21530-pro_0000038062(display_long)	psi-mi:"MI:0096"(pull down)	Doceul et al. (2008)	pubmed:18632959|imex:IM-26008	taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)")	taxid:11098(csfvb)|taxid:11098("Classical swine fever virus (strain Brescia)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-12559389|imex:IM-26008-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034142"(toll-like receptor 4 signaling pathway)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0070427"(nucleotide-binding oligomerization domain containing 1 signaling pathway)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|ensembl:ENSSSCG00000001952(gene)|ensembl:ENSSSCG00015029389(gene)|ensembl:ENSSSCG00025067390(gene)|ensembl:ENSSSCG00030058851(gene)|ensembl:ENSSSCG00035073638(gene)|ensembl:ENSSSCG00045010107(gene)|ensembl:ENSSSCG00050006268(gene)|ensembl:ENSSSCG00055029632(gene)|ensembl:ENSSSCG00060065186(gene)|ensembl:ENSSSCG00065059454(gene)|ensembl:ENSSSCG00070007418(gene)|ensembl:ENSSSCG00040041514(gene)|ensembl:ENSSSCT00000002184(transcript)|ensembl:ENSSSCT00015039015(transcript)|ensembl:ENSSSCT00025092560(transcript)|ensembl:ENSSSCT00030082138(transcript)|ensembl:ENSSSCT00035099812(transcript)|ensembl:ENSSSCT00040055590(transcript)|ensembl:ENSSSCT00045017158(transcript)|ensembl:ENSSSCT00050008579(transcript)|ensembl:ENSSSCT00055058871(transcript)|ensembl:ENSSSCT00060088999(transcript)|ensembl:ENSSSCT00065081421(transcript)|ensembl:ENSSSCT00070014299(transcript)|ensembl:ENSSSCT00070014305(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007253"(cytoplasmic sequestering of NF-kappaB)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0010745"(negative regulation of macrophage derived foam cell differentiation)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010888"(negative regulation of lipid storage)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|reactome:R-SSC-1810476|reactome:R-SSC-202424|reactome:R-SSC-209560|reactome:R-SSC-2871837|reactome:R-SSC-445989|reactome:R-SSC-5607764|reactome:R-SSC-5689880|reactome:R-SSC-9020702|reactome:R-SSC-933542|reactome:R-SSC-1169091|refseq:NP_001005150.1	intact:EBI-9523036(chain-parent)	-	-	chain-seq-start:1|chain-seq-end:168	figure legend:3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9823(pig-max)|taxid:9823(Max kidney cell line)	-	2016/10/11	2017/08/09	rogid:4WzpOxVa0CNXUWMqQsVRGsz7Mdg9823	rogid:E8+isF/QCbF8O+au5LRoMKMQKKA11098	rigid:kwMB8AyqfTLA5GBqstUanl21Kmo	false	v5 tag:?-?|his tag:?-?	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q08353	uniprotkb:P21530-PRO_0000038062	intact:EBI-12558699|ensembl:ENSSSCP00000002133|ensembl:ENSSSCP00015015516|ensembl:ENSSSCP00025040620|ensembl:ENSSSCP00030037706|ensembl:ENSSSCP00035042295|ensembl:ENSSSCP00040023108|ensembl:ENSSSCP00045011831|ensembl:ENSSSCP00050003687|ensembl:ENSSSCP00055047145|ensembl:ENSSSCP00060038508|ensembl:ENSSSCP00065035456|ensembl:ENSSSCP00070011807|ensembl:ENSSSCP00070011804|uniprotkb:F2Q9A9	intact:EBI-12558622	psi-mi:ikba_pig(display_long)|uniprotkb:NFKBIA(gene name)|psi-mi:NFKBIA(display_short)|uniprotkb:IKBA(gene name synonym)|uniprotkb:ECI-6(gene name synonym)|uniprotkb:I-kappa-B-alpha(gene name synonym)	psi-mi:p21530-pro_0000038062(display_long)	psi-mi:"MI:0096"(pull down)	Doceul et al. (2008)	pubmed:18632959|imex:IM-26008	taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)")	taxid:11098(csfvb)|taxid:11098("Classical swine fever virus (strain Brescia)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-12559403|imex:IM-26008-15	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034142"(toll-like receptor 4 signaling pathway)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0070427"(nucleotide-binding oligomerization domain containing 1 signaling pathway)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|ensembl:ENSSSCG00000001952(gene)|ensembl:ENSSSCG00015029389(gene)|ensembl:ENSSSCG00025067390(gene)|ensembl:ENSSSCG00030058851(gene)|ensembl:ENSSSCG00035073638(gene)|ensembl:ENSSSCG00045010107(gene)|ensembl:ENSSSCG00050006268(gene)|ensembl:ENSSSCG00055029632(gene)|ensembl:ENSSSCG00060065186(gene)|ensembl:ENSSSCG00065059454(gene)|ensembl:ENSSSCG00070007418(gene)|ensembl:ENSSSCG00040041514(gene)|ensembl:ENSSSCT00000002184(transcript)|ensembl:ENSSSCT00015039015(transcript)|ensembl:ENSSSCT00025092560(transcript)|ensembl:ENSSSCT00030082138(transcript)|ensembl:ENSSSCT00035099812(transcript)|ensembl:ENSSSCT00040055590(transcript)|ensembl:ENSSSCT00045017158(transcript)|ensembl:ENSSSCT00050008579(transcript)|ensembl:ENSSSCT00055058871(transcript)|ensembl:ENSSSCT00060088999(transcript)|ensembl:ENSSSCT00065081421(transcript)|ensembl:ENSSSCT00070014299(transcript)|ensembl:ENSSSCT00070014305(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007253"(cytoplasmic sequestering of NF-kappaB)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0010745"(negative regulation of macrophage derived foam cell differentiation)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010888"(negative regulation of lipid storage)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|reactome:R-SSC-1810476|reactome:R-SSC-202424|reactome:R-SSC-209560|reactome:R-SSC-2871837|reactome:R-SSC-445989|reactome:R-SSC-5607764|reactome:R-SSC-5689880|reactome:R-SSC-9020702|reactome:R-SSC-933542|reactome:R-SSC-1169091|refseq:NP_001005150.1	intact:EBI-9523036(chain-parent)	-	-	chain-seq-start:1|chain-seq-end:168	figure legend:3|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9823(pig-max)|taxid:9823(Max kidney cell line)	-	2016/10/11	2017/08/09	rogid:4WzpOxVa0CNXUWMqQsVRGsz7Mdg9823	rogid:E8+isF/QCbF8O+au5LRoMKMQKKA11098	rigid:kwMB8AyqfTLA5GBqstUanl21Kmo	false	glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)